CN106998749A - 避免抗微生物剂抗性的抗腹泻制剂 - Google Patents

避免抗微生物剂抗性的抗腹泻制剂 Download PDF

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Publication number
CN106998749A
CN106998749A CN201580045389.4A CN201580045389A CN106998749A CN 106998749 A CN106998749 A CN 106998749A CN 201580045389 A CN201580045389 A CN 201580045389A CN 106998749 A CN106998749 A CN 106998749A
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CN
China
Prior art keywords
formulation
bromelain
animal
piglets
disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201580045389.4A
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English (en)
Chinese (zh)
Inventor
特蕾西·L·迈诺特
约翰·沃尔什
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Anatara Lifesciences Ltd
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Anatara Lifesciences Ltd
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Priority to CN202111584816.XA priority Critical patent/CN114711336A/zh
Publication of CN106998749A publication Critical patent/CN106998749A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4873—Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/189—Enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/60—Feeding-stuffs specially adapted for particular animals for weanlings
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/80—Feeding-stuffs specially adapted for particular animals for aquatic animals, e.g. fish, crustaceans or molluscs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/22—Cysteine endopeptidases (3.4.22)
    • C12Y304/22032—Stem bromelain (3.4.22.32)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/22—Cysteine endopeptidases (3.4.22)
    • C12Y304/22033—Fruit bromelain (3.4.22.33), i.e. juice bromelain
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/30—Foods, ingredients or supplements having a functional effect on health
    • A23V2200/32—Foods, ingredients or supplements having a functional effect on health having an effect on the health of the digestive tract
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Organic Chemistry (AREA)
  • Birds (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Insects & Arthropods (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physiology (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Fodder In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201580045389.4A 2014-08-25 2015-08-24 避免抗微生物剂抗性的抗腹泻制剂 Pending CN106998749A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202111584816.XA CN114711336A (zh) 2014-08-25 2015-08-24 避免抗微生物剂抗性的抗腹泻制剂

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462041175P 2014-08-25 2014-08-25
US62/041,175 2014-08-25
PCT/US2015/046509 WO2016032944A1 (en) 2014-08-25 2015-08-24 Anti-diarrhea formulation which avoids antimicrobial resistance

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202111584816.XA Division CN114711336A (zh) 2014-08-25 2015-08-24 避免抗微生物剂抗性的抗腹泻制剂

Publications (1)

Publication Number Publication Date
CN106998749A true CN106998749A (zh) 2017-08-01

Family

ID=55400400

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CN201580045389.4A Pending CN106998749A (zh) 2014-08-25 2015-08-24 避免抗微生物剂抗性的抗腹泻制剂
CN202111584816.XA Pending CN114711336A (zh) 2014-08-25 2015-08-24 避免抗微生物剂抗性的抗腹泻制剂

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Country Link
US (1) US20170239334A1 (enExample)
EP (1) EP3193629B1 (enExample)
JP (1) JP6920199B2 (enExample)
KR (1) KR102382930B1 (enExample)
CN (2) CN106998749A (enExample)
AU (2) AU2015306904A1 (enExample)
CA (1) CA2959361A1 (enExample)
DK (1) DK3193629T3 (enExample)
ES (1) ES2938347T3 (enExample)
PH (1) PH12017500338B1 (enExample)
WO (1) WO2016032944A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114585380A (zh) * 2019-10-11 2022-06-03 安纳塔拉生命科学有限公司 胃肠健康组合物
EP4117646A1 (en) * 2020-03-12 2023-01-18 Abbott Laboratories Methods of treating diarrhea or inflammatory conditions of the gut
CN112618579B (zh) * 2020-12-24 2022-02-15 南京农业大学 一种防治仔猪腹泻复合益生菌制剂和制备方法及应用
US20240122953A1 (en) * 2021-02-16 2024-04-18 Dsm Ip Assets B.V. Methods for reducing pathogenic e coli by selective feed additive intervention
PL246387B1 (pl) * 2022-08-16 2025-01-20 Nutropharma Spolka Z Ograniczona Odpowiedzialnoscia Kompozycja doustna i jej zastosowanie
KR102592953B1 (ko) * 2023-01-30 2023-10-20 박예성 휴지기 없이 급여 가능한 반려동물용 영양제 제조공법
CN116889261B (zh) * 2023-07-22 2025-07-04 广东加大实业有限公司 一种防治腹泻乳猪饲料及其制备方法

Citations (2)

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CN1548154A (zh) * 2003-05-22 2004-11-24 维奥（四川）生物技术有限公司 用于治疗哺乳动物腹泻的菠萝蛋白酶微胶囊化药物组合物
US20060052438A1 (en) * 2004-04-30 2006-03-09 Chi-Tang Ho Bioactive compounds and methods of uses thereof

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ATE106242T1 (de) * 1986-08-28 1994-06-15 Enzacor Pty Ltd Mikrogranuläre zubereitung zur verabreichung biologisch aktiver stoffe in den eingeweideregionen von tieren.
WO1993001800A1 (en) * 1991-07-24 1993-02-04 Thomas Sai Ying Ko Therapeutic compositions and methods
US6054261A (en) * 1998-05-20 2000-04-25 Q-Pharma, Inc. Coenzyme Q10 compositions for organ protection during perfusion
US6080403A (en) * 1998-06-18 2000-06-27 Star-Kist Foods, Inc. Protease containing hairball remedy and use thereof
WO2003068008A1 (en) * 2002-02-14 2003-08-21 Dsm Ip Assets B.V. Water-dispersible coenzyme q10 dry powders
WO2008049437A1 (en) * 2006-10-26 2008-05-02 Biofiber-Damino A/S Composition comprising lignin and antidi arrheal component
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AT506095A1 (de) * 2007-12-03 2009-06-15 Volopharm Gmbh Verwendung von proteasen
CA3050530A1 (en) * 2009-01-06 2010-07-15 Galenagen, Llc Compositions and methods for the treatment or prevention of staphylococcus aureus infections and for the eradication or reduction of staphylococcus aureus on surfaces

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
CN1548154A (zh) * 2003-05-22 2004-11-24 维奥（四川）生物技术有限公司 用于治疗哺乳动物腹泻的菠萝蛋白酶微胶囊化药物组合物
US20060052438A1 (en) * 2004-04-30 2006-03-09 Chi-Tang Ho Bioactive compounds and methods of uses thereof

Non-Patent Citations (1)

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赵力超等: "多糖和添加剂对菠萝茎蛋白酶活力的影响", 《食品科学》 *

Also Published As

Publication number Publication date
JP2017532369A (ja) 2017-11-02
AU2015306904A1 (en) 2017-04-06
KR20170082149A (ko) 2017-07-13
US20170239334A1 (en) 2017-08-24
WO2016032944A4 (en) 2016-04-28
DK3193629T3 (da) 2023-03-13
PH12017500338A1 (en) 2017-07-17
CN114711336A (zh) 2022-07-08
CA2959361A1 (en) 2016-03-03
WO2016032944A1 (en) 2016-03-03
EP3193629A1 (en) 2017-07-26
ES2938347T3 (es) 2023-04-10
KR102382930B1 (ko) 2022-04-04
EP3193629B1 (en) 2023-01-25
AU2019204496A1 (en) 2019-07-18
AU2019204496B2 (en) 2020-12-24
PH12017500338B1 (en) 2023-01-13
JP6920199B2 (ja) 2021-08-18
EP3193629A4 (en) 2018-07-11

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