CN106994149A - It is a kind of to treat pharmaceutical composition of hypertension and preparation method thereof, preparation and application - Google Patents
It is a kind of to treat pharmaceutical composition of hypertension and preparation method thereof, preparation and application Download PDFInfo
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- CN106994149A CN106994149A CN201710290751.5A CN201710290751A CN106994149A CN 106994149 A CN106994149 A CN 106994149A CN 201710290751 A CN201710290751 A CN 201710290751A CN 106994149 A CN106994149 A CN 106994149A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/51—Gentianaceae (Gentian family)
- A61K36/515—Gentiana
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/24—Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
- A61K36/296—Epimedium
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/536—Prunella or Brunella (selfheal)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/744—Gardenia
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/754—Evodia
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- A—HUMAN NECESSITIES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
Abstract
The invention discloses a kind of pharmaceutical composition for treating hypertension and preparation method thereof, preparation and application.The pharmaceutical composition of described treatment hypertension includes 10 ~ 30 parts of the scorpio of parts by weight of raw materials, 8 ~ 20 parts of centipede, 60 ~ 100 parts of dendrobium candidum, raw 10 ~ 20 parts of pangolin, 5 ~ 15 parts of stiff silkworm, raw 3 ~ 8 parts of army, 10 ~ 20 parts of radix bupleuri, 5 ~ 15 parts of the root of herbaceous peony, 3 ~ 8 parts of the banksia rose, 3 ~ 8 parts of frankincense, 3 ~ 8 parts of mountain Cape jasmine, 5 ~ 10 parts of rascal, 10 ~ 15 parts of dried orange peel, 15 ~ 30 parts of the capsule of weeping forsythia, 8 ~ 15 parts of Exocarpium Citri Rubrum, 2 ~ 10 parts of bulbus fritillariae cirrhosae, 5 ~ 10 parts of the radix paeoniae rubrathe, 3 ~ 7 parts of the root bark of tree peony, 20 ~ 50 parts of dandelion, 2 ~ 8 parts of honeysuckle flower, 3 ~ 8 parts of 2 ~ 5 parts of cordyceps sinensis and licorice.Preparation is adds tablet, powder, capsule, granule and the pill of the preparation of pharmaceutically acceptable auxiliary material in the pharmaceutical composition of described treatment hypertension.Using application of the pharmaceutical composition for described treatment hypertension in treatment hypertension drug is prepared.The all medicine joints of the present invention, synergy cures mainly hypertension.
Description
Technical field
The invention belongs to pharmaceutical technology field, and in particular to a kind of pharmaceutical composition for treating hypertension and its preparation side
Method, preparation and application.
Background technology
Hypertension（hypertension）Refer to systemic arterial blood pressure（Systolic pressure and/or diastolic pressure）Increase to be main
Feature（The millimetres of mercury of systolic pressure >=140, the millimetres of mercury of diastolic pressure >=90）, can with the organs such as the heart, brain, kidney function or device matter
Property infringement clinical syndrome.Hypertension is most common chronic disease, is also the topmost hazards of cardiovascular and cerebrovascular diseases.Normally
The blood pressure of people is fluctuated within the specific limits with internal and external environment change.In overall crowd, blood pressure level gradually rises with the age, to receive
Contractive pressure is become apparent, but downward trend is presented in diastolic pressure after 50 years old, and pulse pressure is also increased therewith.In recent years, people are to cardiovascular disease
The effect of multiple risk factors and the heart, brain, the understanding of kidney target-organ protection deepen continuously, and the diagnostic criteria of hypertension is not yet
Break and adjust, it is now recognized that the danger that cardiovascular disease occurs for the patient of same blood pressure level is different, therefore have the general of blood pressure layering
Read, that is, occur the different patient of cardiovascular disease risk factor, suitable blood pressure level there should be difference.Pressure value and hazard factor assessment are
Diagnosis and the Main Basiss for formulating hypertension therapeutic scheme, the target of different patient's hypertension management are different, and doctor faces patient
When on the basis of normative reference, the most suitable blood pressure range of the patient is judged according to its concrete condition, using targetedly controlling
Treatment measure.On the basis of the mode of making the life better, it is recommended to use 24 hours long-acting antihypertensive drugs control blood pressures.Except assessment clinic blood
Pressure is outer, and patient should also be noted that the monitoring and management of family's Morning Blood Pressure, to control blood pressure, reduces the generation of cardiocerebrovasculaevents events
Rate.The types of drugs for the treatment of hypertension is various at present, but side effect is larger, and individual selects the more difficult control of medicine suitability, dressing wind
It is dangerous very big, therefore, develop it is a kind of can solve above-mentioned problem, the medicine that meets Therapy of Patients with Hypertension demand is very must
Want.
The content of the invention
The first object of the present invention is to provide a kind of pharmaceutical composition for treating hypertension；Second purpose is to provide institute
The preparation method of the pharmaceutical composition for the treatment hypertension stated；3rd purpose is the medicine group of the treatment hypertension described in offer
The preparation of compound；4th purpose is the application of the pharmaceutical composition of the treatment hypertension described in offer.
The first object of the present invention is achieved in that the pharmaceutical composition of described treatment hypertension includes raw material weight
30 ~ 70 parts of the felwort of part, 30 ~ 70 parts of radix scutellariae, 20 ~ 50 parts of cape jasmine, 5 ~ 15 parts of paenoiae alba, 3 ~ 8 parts of Radix Rehmanniae, radix bupleuri 15 ~ 30
Part, 15 ~ 30 parts of cassia seed, raw 5 ~ 15 parts of sophora flower, 20 ~ 70 parts of the root of kudzu vine, 15 ~ 30 parts of yncaria stem with hooks, 8 ~ 15 parts of selfheal, chrysanthemum 8 ~ 15
Part, 8 ~ 20 parts of hawthorn, 8 ~ 15 parts of barrenwort, 8 ~ 30 parts of bluish dogbane, 8 ~ 30 parts of earthworm, 5 ~ 15 parts of evodia rutaecarpa.
The second object of the present invention, which is achieved in that, pulverizes and sieves each bulk drug, well mixed by formulation ratio
Obtain the pharmaceutical composition that object treats hypertension.
The third object of the present invention is achieved in that in the pharmaceutical composition of described treatment hypertension and added pharmaceutically
Tablet, powder, capsule, granule and pill prepared by acceptable auxiliary material.
The fourth object of the present invention is achieved in that the pharmaceutical composition of described treatment hypertension is preparing treatment height
Application in blood pressure medication.
The pharmaceutical composition for the treatment of hypertension of the present invention is using bluish dogbane and earthworm as monarch drug in a prescription, and bluish dogbane is sweet, property
It is cool, enter Liver Channel, soothing the liver is calmed the nerves, clearing away heat and promoting diuresis；Earthworm is cold in nature, and taste is salty, enters Liver Channel, The flat liver of heat-clearing, relieving convulsion and spasm, relieving asthma, diuresis,
Dredging collateral eliminating impediment；It is ministerial drug with same felwort, radix scutellariae and evodia rutaecarpa, while compatibility cape jasmine, paenoiae alba, Radix Rehmanniae, radix bupleuri, Cassia
Son, raw sophora flower, the root of kudzu vine, yncaria stem with hooks, selfheal, chrysanthemum, hawthorn and barrenwort, all medicine joints, synergy cure mainly hypertension.This hair
The pharmaceutical composition determined curative effect of bright described treatment hypertension, safely controllable, patient is easy to receiving, it is easy to promote the use of etc. excellent
Point, its primary crude drug is all autonomic drug, and safety non-toxic, clinic further genralrlization is used.
Embodiment
With reference to embodiment, the present invention is further illustrated, but the present invention is not any limitation as in any way,
Based on present invention teach that any conversion or replacement made, belong to protection scope of the present invention.
The pharmaceutical composition for the treatment of hypertension of the present invention includes 30 ~ 70 parts of the felwort of parts by weight of raw materials, radix scutellariae
30 ~ 70 parts, 20 ~ 50 parts of cape jasmine, 5 ~ 15 parts of paenoiae alba, 3 ~ 8 parts of Radix Rehmanniae, 15 ~ 30 parts of radix bupleuri, 15 ~ 30 parts of cassia seed, raw sophora flower
5 ~ 15 parts, 20 ~ 70 parts of the root of kudzu vine, 15 ~ 30 parts of yncaria stem with hooks, 8 ~ 15 parts of selfheal, 8 ~ 15 parts of chrysanthemum, 8 ~ 20 parts of hawthorn, barrenwort 8 ~ 15
Part, 8 ~ 30 parts of bluish dogbane, 8 ~ 30 parts of earthworm, 5 ~ 15 parts of evodia rutaecarpa.
The pharmaceutical composition of described treatment hypertension includes 40 ~ 50 parts of the felwort of parts by weight of raw materials, radix scutellariae 40 ~ 50
Part, 30 ~ 40 parts of cape jasmine, 8 ~ 12 parts of paenoiae alba, 4 ~ 6 parts of Radix Rehmanniae, 20 ~ 25 parts of radix bupleuri, 20 ~ 25 parts of cassia seed, raw sophora flower 8 ~ 12
Part, 40 ~ 60 parts of the root of kudzu vine, 15 ~ 20 parts of yncaria stem with hooks, 10 ~ 12 parts of selfheal, 10 ~ 15 parts of chrysanthemum, 15 ~ 20 parts of hawthorn, barrenwort 8 ~ 11
Part, 20 ~ 30 parts of bluish dogbane, 10 ~ 20 parts of earthworm, 10 ~ 15 parts of evodia rutaecarpa.
The pharmaceutical composition of described treatment hypertension includes 50 parts of felwort, 50 parts of radix scutellariae, the cape jasmine of parts by weight of raw materials
35 parts, 10 parts of paenoiae alba, 5 parts of Radix Rehmanniae, 20 parts of radix bupleuri, 20 parts of cassia seed, raw 10 parts of sophora flower, 50 parts of the root of kudzu vine, 20 parts of yncaria stem with hooks, the summer
10 parts of withered grass, 10 parts of chrysanthemum, 10 parts of hawthorn, 10 parts of barrenwort, 20 parts of bluish dogbane, 20 parts of earthworm, 10 parts of evodia rutaecarpa.
The pharmaceutical composition of described treatment hypertension includes 40 parts of felwort, 50 parts of radix scutellariae, the cape jasmine of parts by weight of raw materials
40 parts, 12 parts of paenoiae alba, 6 parts of Radix Rehmanniae, 22 parts of radix bupleuri, 22 parts of cassia seed, raw 11 parts of sophora flower, 50 parts of the root of kudzu vine, 18 parts of yncaria stem with hooks, the summer
11 parts of withered grass, 12 parts of chrysanthemum, 18 parts of hawthorn, 9 parts of barrenwort, 30 parts of bluish dogbane, 20 parts of earthworm, 15 parts of evodia rutaecarpa.
The preparation method of the pharmaceutical composition for the treatment of hypertension of the present invention, is that each bulk drug pulverizes and sieves, presses
Formulation ratio is well mixed to obtain the pharmaceutical composition that object treats hypertension.
Described pulverizing and sieving is to crush 100 mesh sieves.
The preparation of the pharmaceutical composition for the treatment of hypertension of the present invention is the drug regimen of described treatment hypertension
Tablet, powder, capsule, granule and pill prepared by pharmaceutically acceptable auxiliary material are added in thing.
The application of the pharmaceutical composition for the treatment of hypertension of the present invention is the drug regimen of described treatment hypertension
Application of the thing in treatment hypertension drug is prepared.
So that case is embodied, the present invention will be further described below：
Embodiment 1
Take raw material felwort 30g, radix scutellariae 30g, cape jasmine 20g, paenoiae alba 5g, Radix Rehmanniae 3g, radix bupleuri 15g, cassia seed 15g, raw Chinese scholartree
Flower 5g, the g of the root of kudzu vine 20, yncaria stem with hooks 15g, selfheal 8g, chrysanthemum 8g, the g of hawthorn 8, the g of barrenwort 8, the g of bluish dogbane 8, earthworm 8g and Wu
Fruit of medicinal cornel 5g, crushed 100 mesh sieves respectively, well mixed to obtain the pharmaceutical composition that object treats hypertension.
Embodiment 2
Take the g of raw material felwort 70, the g of radix scutellariae 70, the g of cape jasmine 50, the g of paenoiae alba 15, the g of Radix Rehmanniae 8, the g of radix bupleuri 30, cassia seed 30
G, the raw g of sophora flower 15, the g of the root of kudzu vine 70, the g of yncaria stem with hooks 30, the g of selfheal 15, the g of chrysanthemum 15, the g of hawthorn 20, the g of barrenwort 15, bluish dogbane
30 g, the g of earthworm 30 and the g of evodia rutaecarpa 15, crushed 100 mesh sieves respectively, well mixed to obtain the medicine that object treats hypertension
Compositions.
Embodiment 3
Take raw material felwort 30g, the g of radix scutellariae 50, the g of cape jasmine 50, the g of paenoiae alba 5, the g of Radix Rehmanniae 5, the g of radix bupleuri 20, cassia seed 20
G, the raw g of sophora flower 10, the g of the root of kudzu vine 70, the g of yncaria stem with hooks 30, the g of selfheal 15, the g of chrysanthemum 15, the g of hawthorn 8, the g of barrenwort 8, bluish dogbane 8
G, the g of earthworm 8 and the g of evodia rutaecarpa 11, crushed 100 mesh sieves respectively, well mixed to obtain the medicine group that object treats hypertension
Compound.
Embodiment 4
Take the g of raw material felwort 50, the g of radix scutellariae 50, the g of cape jasmine 35, the g of paenoiae alba 10, the g of Radix Rehmanniae 5, the g of radix bupleuri 20, cassia seed 20
G, the raw g of sophora flower 10, the g of the root of kudzu vine 50, the g of yncaria stem with hooks 20, the g of selfheal 10, the g of chrysanthemum 10, the g of hawthorn 10, the g of barrenwort 10, bluish dogbane
20 g, the g of earthworm 20 and the g of evodia rutaecarpa 10, crushed 100 mesh sieves respectively, well mixed to obtain the medicine that object treats hypertension
Compositions.
Embodiment 5
Take the g of raw material felwort 40, the g of radix scutellariae 50, the g of cape jasmine 40, the g of paenoiae alba 12, the g of Radix Rehmanniae 6, the g of radix bupleuri 22, cassia seed 22
G, the raw g of sophora flower 11, the g of the root of kudzu vine 50, the g of yncaria stem with hooks 18, the g of selfheal 11, the g of chrysanthemum 12, the g of hawthorn 18, the g of barrenwort 9, bluish dogbane
30 g, the g of earthworm 20 and the g of evodia rutaecarpa 15, crushed 100 mesh sieves respectively, well mixed to obtain the medicine that object treats hypertension
Compositions.
Embodiment 6
Take raw material felwort 40g, the g of radix scutellariae 40, cape jasmine 30g, paenoiae alba 8g, Radix Rehmanniae 4g, radix bupleuri 20g, cassia seed 20g, raw Chinese scholartree
Flower 8g, root of kudzu vine 40g, the g of yncaria stem with hooks 15, selfheal 10g, chrysanthemum 10g, the g of hawthorn 15, the g of barrenwort 8, bluish dogbane 20g, earthworm 10g
With evodia rutaecarpa 10g, 100 mesh sieves were crushed respectively, it is well mixed to obtain the pharmaceutical composition that object treats hypertension.
Embodiment 7
Take the g of raw material felwort 50, the g of radix scutellariae 50, cape jasmine 40g, paenoiae alba 12g, the g of Radix Rehmanniae 6, the g of radix bupleuri 25, cassia seed 25g,
Raw sophora flower 12g, root of kudzu vine 60g, the g of yncaria stem with hooks 20, the g of selfheal 12, the g of chrysanthemum 15, the g of hawthorn 20, the g of barrenwort 11, bluish dogbane 30
G, the g of earthworm 20 and the g of evodia rutaecarpa 15, crushed 100 mesh sieves respectively, well mixed to obtain the medicine group that object treats hypertension
Compound.
Embodiment 8
Take the g of raw material felwort 45, the g of radix scutellariae 45, cape jasmine 35g, paenoiae alba 10g, Radix Rehmanniae 5g, the g of radix bupleuri 22, cassia seed 22g,
Raw sophora flower 10g, root of kudzu vine 50g, yncaria stem with hooks 18g, the g of selfheal 11, the g of chrysanthemum 12, hawthorn 18g, barrenwort 10g, bluish dogbane 25g,
15 g of the dragon and g of evodia rutaecarpa 12, crushed 100 mesh sieves respectively, well mixed to obtain the drug regimen that object treats hypertension
Thing.
Embodiment 9
Pharmaceutically acceptable auxiliary material is added in the pharmaceutical composition of the treatment hypertension prepared with embodiment 2 to prepare in flakes
Agent.
Embodiment 10
Pharmaceutically acceptable auxiliary material is added in the pharmaceutical composition of the treatment hypertension prepared with embodiment 3 and prepares plastic
Wafer.
Embodiment 11
Pharmaceutically acceptable auxiliary material is added in the pharmaceutical composition of the treatment hypertension prepared with embodiment 4 to be prepared into
Granula.
Embodiment 12
Pharmaceutically acceptable auxiliary material is added in the pharmaceutical composition of the treatment hypertension prepared with embodiment 6 and prepares pelletization
Agent.
Embodiment 13
The pharmaceutical composition prepared respectively with 1 ~ embodiment of embodiment 8 carries out clinical test, total effective rate 99.9%.Below
It is described further with part real case：
Patient Zhang, man 61 years old, has difficulty in breathing 5 years after graduated activity, hence it is evident that aggravate with edema of lower extremity one month, 2011
Year, prominent sense palpitaition during because of mountain-climbing, shortness of breath, uncomfortable in chest, rest is slightly alleviated for about 1 hour.Feel that muscle power increasingly declines, and somewhat lives later
It is dynamic i.e. sense shortness of breath, uncomfortable in chest, awake, no precordial pain is suppressed during night.Once " cardiac arrhythmia " was diagnosed as in locality, medication curative effect is not
It is good；The pharmaceutical composition that the embodiment of the present invention 4 is prepared is taken afterwards, once a day, 4 ~ 6 grams every time, warm water takes, treatment one
Nian Houjing checks that blood pressure recovers normal.
Patient sinus, female, 60 years old, often there is head in sitting motor tumble injury hand (soft tissue bruise) before 2013 afterwards in patient
It is dizzy, palpitaition often can spontaneous remission, unstable blood pressure is fixed, is fluctuated between 120--180/70-110 and takes captopril, nitre benzene
Flat sustained release tablets etc. also control undesirable, and this time premorbid patient is in and cooked, and feels dizzy suddenly, and palpitaition is perspired, tinnitus, from
Buccal nifedipine is invalid, after take the pharmaceutical composition that the embodiment of the present invention 5 is prepared, once a day, 4 ~ 6 grams every time,
Warm water takes, through checking that blood pressure recovers normal after treatment half a year.
42 years old, there is headache and dizzy in 2015, headache portion continues positioned at overhead without obvious inducement in patient Ouyang, female
Property distending pain based on, it is dizzy to ignore thing rotation without tinnitus without vomiting, have when having a headache obvious and blush measuring blood pressure rise at that time and be up to
200/140mmHg, gives the treatment of oral blood pressure lowering medicine in local clinic, to no effect, after take the embodiment of the present invention 6 and prepare
Pharmaceutical composition, once a day, 4 ~ 6 grams every time, warm water takes, and treatment checks that blood pressure recovers normal, headache and dizzy after 4 months
Symptom disappears.
Patient Mr. Wang, male 54 years old, hypertension history 5 years, takes indapamide tablets always, after due to effect it is not good clothes change
Treated with Captopril tablets, to no effect, after take the pharmaceutical composition that the embodiment of the present invention 1 is prepared, once a day, every time
5 ~ 8g, warm water takes, and checks that blood pressure recovers normal after treatment a year and a half, related symptoms disappear.
Claims (8)
1. a kind of pharmaceutical composition for treating hypertension, it is characterised in that the pharmaceutical composition of described treatment hypertension includes original
30 ~ 70 parts of the felwort of material parts by weight, 30 ~ 70 parts of radix scutellariae, 20 ~ 50 parts of cape jasmine, 5 ~ 15 parts of paenoiae alba, 3 ~ 8 parts of Radix Rehmanniae, radix bupleuri
15 ~ 30 parts, 15 ~ 30 parts of cassia seed, raw 5 ~ 15 parts of sophora flower, 20 ~ 70 parts of the root of kudzu vine, 15 ~ 30 parts of yncaria stem with hooks, 8 ~ 15 parts of selfheal, chrysanthemum 8
~ 15 parts, 8 ~ 20 parts of hawthorn, 8 ~ 15 parts of barrenwort, 8 ~ 30 parts of bluish dogbane, 8 ~ 30 parts of earthworm, 5 ~ 15 parts of evodia rutaecarpa.
2. the pharmaceutical composition for the treatment of hypertension according to claim 1, it is characterised in that described treatment hypertension
40 ~ 50 parts of the felwort of pharmaceutical composition including parts by weight of raw materials, 40 ~ 50 parts of radix scutellariae, 30 ~ 40 parts of cape jasmine, 8 ~ 12 parts of paenoiae alba,
4 ~ 6 parts of Radix Rehmanniae, 20 ~ 25 parts of radix bupleuri, 20 ~ 25 parts of cassia seed, raw 8 ~ 12 parts of sophora flower, 40 ~ 60 parts of the root of kudzu vine, 15 ~ 20 parts of yncaria stem with hooks, summer
10 ~ 12 parts of withered grass, 10 ~ 15 parts of chrysanthemum, 15 ~ 20 parts of hawthorn, 8 ~ 11 parts of barrenwort, 20 ~ 30 parts of bluish dogbane, 10 ~ 20 parts of earthworm, Wu
10 ~ 15 parts of the fruit of medicinal cornel.
3. the pharmaceutical composition for the treatment of hypertension according to claim 1, it is characterised in that described treatment hypertension
50 parts of the felwort of pharmaceutical composition including parts by weight of raw materials, 50 parts of radix scutellariae, 35 parts of cape jasmine, 10 parts of paenoiae alba, 5 parts of Radix Rehmanniae,
20 parts of radix bupleuri, 20 parts of cassia seed, raw 10 parts of sophora flower, 50 parts of the root of kudzu vine, 20 parts of yncaria stem with hooks, 10 parts of selfheal, 10 parts of chrysanthemum, hawthorn 10
Part, 10 parts of barrenwort, 20 parts of bluish dogbane, 20 parts of earthworm, 10 parts of evodia rutaecarpa.
4. the pharmaceutical composition for the treatment of hypertension according to claim 1, it is characterised in that described treatment hypertension
40 parts of the felwort of pharmaceutical composition including parts by weight of raw materials, 50 parts of radix scutellariae, 40 parts of cape jasmine, 12 parts of paenoiae alba, 6 parts of Radix Rehmanniae,
22 parts of radix bupleuri, 22 parts of cassia seed, raw 11 parts of sophora flower, 50 parts of the root of kudzu vine, 18 parts of yncaria stem with hooks, 11 parts of selfheal, 12 parts of chrysanthemum, hawthorn 18
Part, 9 parts of barrenwort, 30 parts of bluish dogbane, 20 parts of earthworm, 15 parts of evodia rutaecarpa.
5. the preparation method of the pharmaceutical composition of any described treatment hypertension of a kind of claim 1 ~ 4, it is characterised in that be
Each bulk drug is pulverized and sieved, the pharmaceutical composition that object treats hypertension is obtained by formulation ratio is well mixed.
6. the preparation method of the pharmaceutical composition for the treatment of hypertension according to claim 5, it is characterised in that described powder
Broken sieving is to crush 100 mesh sieves.
7. the preparation of the pharmaceutical composition of any described treatment hypertension of a kind of claim 1 ~ 4, it is characterised in that described
Added in the pharmaceutical composition for treating hypertension tablet, powder, capsule, granule prepared by pharmaceutically acceptable auxiliary material and
Pill.
8. the application of the pharmaceutical composition of any described treatment hypertension of a kind of claim 1 ~ 4, it is characterised in that described
Treat application of the pharmaceutical composition of hypertension in treatment hypertension drug is prepared.
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| CN201710290751.5A CN106994149A (en) | 2017-04-28 | 2017-04-28 | It is a kind of to treat pharmaceutical composition of hypertension and preparation method thereof, preparation and application |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111870675A (en) * | 2020-07-06 | 2020-11-03 | 于毳 | Traditional Chinese medicine fumigation liquid and preparation method and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101559182A (en) * | 2009-05-13 | 2009-10-21 | 武兴战 | Traditional Chinese medicine for treating hyperpiesis and preparation method |
| CN101732473A (en) * | 2008-11-22 | 2010-06-16 | 陈恒树 | Chinese medicinal pills for treating hypertension |
| CN104840776A (en) * | 2015-06-03 | 2015-08-19 | 广西大学 | Traditional Chinese medicine for reducing blood pressure |
-
2017
- 2017-04-28 CN CN201710290751.5A patent/CN106994149A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101732473A (en) * | 2008-11-22 | 2010-06-16 | 陈恒树 | Chinese medicinal pills for treating hypertension |
| CN101559182A (en) * | 2009-05-13 | 2009-10-21 | 武兴战 | Traditional Chinese medicine for treating hyperpiesis and preparation method |
| CN104840776A (en) * | 2015-06-03 | 2015-08-19 | 广西大学 | Traditional Chinese medicine for reducing blood pressure |
Non-Patent Citations (2)
| Title |
|---|
| 刘志兰: "辨证治疗高血压 60 例临床观察", 《光明中医》 * |
| 杜立峰等: "平肝降压胶囊对原发性高血压患者血浆内皮素和血管紧张素II的影响", 《中国临床康复》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111870675A (en) * | 2020-07-06 | 2020-11-03 | 于毳 | Traditional Chinese medicine fumigation liquid and preparation method and application thereof |
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Application publication date: 20170801 |