CN102940736B - A Chinese medicinal composition for preventing and treating cervical spondylosis, and its preparation method - Google Patents
A Chinese medicinal composition for preventing and treating cervical spondylosis, and its preparation method Download PDFInfo
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Abstract
本发明属于中药领域,公开了一种预防和治疗颈椎病的中药组合物。本发明所述中药组合物由桂枝、细辛、白芷、川芎、红花、丹参、白芍、透骨草、伸筋草、当归、蔓荆子、制川乌、制草乌、埔姜籽、合欢皮为原料制备而成,具有活血化瘀,舒筋通络,祛风止痛、软化血管之功效,对颈椎病、动脉硬化均有和很好的疗效,应用中医内病外治的原理,使病人不打针,不吃药,不按摩,不理疗,不去医院,不影响工作和学习而达到治病的目的。同时本发明所用药材均无毒,长期使用药物依赖性小,且价格低廉,适合短期及长期使用,具有广阔的市场前景。The invention belongs to the field of Chinese medicine, and discloses a Chinese medicine composition for preventing and treating cervical spondylosis. The Chinese medicine composition of the present invention is prepared by cassia twig, asarum, angelica dahurica, chuanxiong, safflower, salvia miltiorrhiza, white peony root, scutellaria baicalensis, schizonepeta tenuifolia, angelica sinensis, vitex rotundus, processed chuanwu, processed kusnezoffii, pujiang seeds, and julibrissin bark as raw materials, and has the effects of promoting blood circulation and removing blood stasis, relaxing muscles and tendons, dredge collaterals, dispelling wind and relieving pain, and softening blood vessels, and has good curative effect on cervical spondylosis and arteriosclerosis, and applies the principle of external treatment of internal diseases of traditional Chinese medicine, so that patients do not need injections, do not take medicine, do not massage, do not have physical therapy, do not go to the hospital, do not affect work and study and achieve the purpose of curing the disease. At the same time, the medicinal materials used in the present invention are all non-toxic, and the long-term use of drug dependence is small, and the price is low, suitable for short-term and long-term use, and has a broad market prospect.
Description
技术领域technical field
本发明属于中药领域,具体涉及一种预防和治疗颈椎病的中药组合物及其制备方法。The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for preventing and treating cervical spondylosis and a preparation method thereof.
背景技术Background technique
颈椎病又称颈椎综合症,是一种以退行性病理改变为基础的疾患。随着人均寿命的提高,发病率也逐渐增加。目前此病发病年龄最小的在32岁左右,年龄50岁以上的的,发病率超过50%,70岁以上,几乎不同程度都有此病,尤其是近几年来,发病率又有不同程度的提高。可见颈椎病己成为中老年人的常见病和多发病。现代医学研究证实,引起人体死亡率较高的脑血管疾病也与颈椎病有密切关系,因此治疗和预防颈椎病显得尤为重要。Cervical spondylosis, also known as cervical syndrome, is a disease based on degenerative pathological changes. With the improvement of life expectancy, the incidence rate is gradually increasing. At present, the youngest age of onset of this disease is about 32 years old, and the incidence rate exceeds 50% for those over 50 years old, and almost all have this disease to varying degrees over the age of 70, especially in recent years, the incidence rate has increased to varying degrees improve. It can be seen that cervical spondylosis has become a common and frequently-occurring disease in middle-aged and elderly people. Modern medical research has confirmed that cerebrovascular diseases that cause higher human mortality are also closely related to cervical spondylosis, so it is particularly important to treat and prevent cervical spondylosis.
人体长期从事伏案或头颈部经常向一侧弯曲的工作以及睡眠枕头高度不当等都会导致人的颈椎和颈后肌群及韧带组织慢性劳损,引起椎间盘变性,髓核弹力减小,向四周隆凸,甚至突出或脱出,椎间松动、失稳,椎间隙变窄,椎体边缘骨刺形成并压迫神经根、椎动脉和脊髓,引起脊神经根出现水肿、肿胀、渗出等反应性炎症,逐渐形成纤维环变性,小关节紊乱、韧带增厚钙化等一系列退行性病理改变,最后导致颈椎病的发生,在临床上出现颈部疼痛,手臂麻木,头晕,头痛,有的伴有恶心呕吐,胸部不适,严重者出现下肢无力,跛行,痉挛性瘫痪,大小便失禁,吞咽困难,也有部分患者出现血压偏高,心绞痛,心率失常,视野缩小,听力下降等症状。The human body has been engaged in desk work for a long time or the head and neck often bend to one side, and the height of the sleeping pillow is not suitable, which will lead to chronic strain of the cervical spine and back of the neck muscles and ligaments, resulting in degeneration of the intervertebral disc, decreased elasticity of the nucleus pulposus, and bulging around. Convexity, even protrusion or prolapse, intervertebral loosening, instability, narrowing of the intervertebral space, formation of bony spurs on the edge of the vertebral body and compression of the nerve roots, vertebral arteries and spinal cord, causing reactive inflammation such as edema, swelling, and exudation of the spinal nerve roots, and gradually A series of degenerative pathological changes such as annular degeneration of fibrosus, facet joint disorder, thickening and calcification of ligaments, etc., finally lead to the occurrence of cervical spondylosis. Clinically, neck pain, arm numbness, dizziness, headache, sometimes accompanied by nausea and vomiting, Chest discomfort. In severe cases, lower limb weakness, lameness, spastic paralysis, incontinence, dysphagia, and some patients have symptoms such as high blood pressure, angina pectoris, arrhythmia, narrowed vision, and hearing loss.
针对上述颈椎病,目前有许多治疗方法,主要有手术和非手术之分。非手术疗法大部分颈椎病患者经非手术治疗效果优良,仅一小部分患者经非手术治疗无效或病情严重而需要手术治疗。For the above-mentioned cervical spondylosis, there are many treatment methods at present, mainly including operation and non-operation. Non-surgical treatment Most patients with cervical spondylosis have excellent curative effect after non-surgical treatment, but only a small number of patients are ineffective or seriously ill and need surgical treatment.
目前报道90~95%的颈椎病患者经过非手术治疗获得痊愈或缓解。非手术治疗目前主要是采用中医、西医、中西医结合以及康复治疗等综合疗法,中医药治疗手段结合西药消炎镇痛、扩张血管、利尿脱水、营养神经等类药物,但是药效不易集中到达患部,疗效不够明显,且长期服用,对人体有毒副作用。It is currently reported that 90-95% of patients with cervical spondylosis are cured or relieved after non-surgical treatment. Non-surgical treatment currently mainly adopts comprehensive therapies such as traditional Chinese medicine, western medicine, combination of traditional Chinese and western medicine, and rehabilitation treatment. Traditional Chinese medicine treatment methods are combined with western medicine for anti-inflammatory and analgesic, dilating blood vessels, diuretic dehydration, and nutritional nerves. However, the efficacy of the medicine is not easy to reach the affected area. , curative effect is not obvious enough, and take for a long time, have toxic side effect to human body.
因此,提供一种疗效肯定而且药源充足能够有效治疗颈椎病的中药组合物具有现实意义。Therefore, it is of practical significance to provide a traditional Chinese medicine composition with a certain curative effect and sufficient drug sources to effectively treat cervical spondylosis.
发明内容Contents of the invention
有鉴于此,本发明的目的在于提供一种疗效肯定、药源充足、效果显著的治疗颈椎病的中药组合物。In view of this, the object of the present invention is to provide a traditional Chinese medicine composition for treating cervical spondylosis with certain curative effect, sufficient drug source and remarkable effect.
为实现本发明的目的,本发明采用如下技术方案:For realizing the purpose of the present invention, the present invention adopts following technical scheme:
一种治疗颈椎病的中药组合物,由如下重量份的原料药制成:A Chinese medicinal composition for the treatment of cervical spondylosis, made of the following raw materials by weight:
桂枝55~65份 细辛65~85份 伸筋草140~160份Guizhi 55~65 parts Asarum 65~85 parts Shenjincao 140~160 parts
川芎65~85份 红花45~55份 丹参140~160份Chuanxiong 65~85 parts Saffron 45~55 parts Salvia 140~160 parts
白芍140~160份 透骨草140~160份 白芷65~85份140~160 parts of Radix Paeoniae Alba, 140~160 parts of Sperantosporum, 65~85 parts of Angelica dahurica
当归45~55份 蔓荆子290~310份 制川乌75~85份Angelica 45~55 parts, Vitex 290~310 parts, Chuanwu 75~85 parts
制草乌75~85份 埔姜籽290~310份 合欢皮140~160份。Make 75~85 parts of Aconitum, 290~310 parts of Pujiang Seed, 140~160 parts of Albizia Juanpi.
中医学关于颈椎病的论述,散见于“眩晕”、“痹证”、“痉证”、“痿证”、“头痛”、“项强”、“颈筋急”、“颈肩痛”等条目,其病机为肝脾肾渐虚、气血不足、营卫失和、血行瘀滞、筋骨失养,加之积劳伤筋,或感受风寒湿邪,致风、痰、瘀互结,脉络瘀滞,经气不利而变生诸症,其肝肾不足为本,风痰瘀为标。本发明所述中药组合物针对患者形成颈椎病的肝脾肾渐虚、气血不足、营卫失和、血行瘀滞、筋骨失养等主要病机选用桂枝、细辛、白芷、川芎、红花、丹参、白芍、透骨草、伸筋草、当归、蔓荆子、制川乌、制草乌、埔姜籽、合欢皮等十五味中药材制成。Discussions on cervical spondylosis in traditional Chinese medicine are scattered in "vertigo", "bi syndrome", "spasmodic syndrome", "atrophy syndrome", "headache", "neck strength", "neck tendon emergency", "neck and shoulder pain", etc. The pathogenesis of liver, spleen and kidney is gradual deficiency, deficiency of qi and blood, disharmony between nutrition and defense, blood stasis, loss of nourishment of muscles and bones, combined with overwork and injury of tendons, or feeling of wind, cold and damp evil, resulting in wind, phlegm, and blood stasis intertwined. Stasis, unfavorable meridian qi and various diseases, its liver and kidney deficiency is the basis, and wind, phlegm and blood stasis are the signs. The traditional Chinese medicine composition of the present invention selects cassia twig, asarum, angelica dahurica, chuanxiong, Made of 15 Chinese herbal medicines including safflower, salvia, white peony root, osmanthus, sinensis, angelica, vitex, sichuan aconitum, zhicaowu, pujiang seed, and acacia bark.
其中桂枝,为樟科常绿乔木植物肉桂的干燥嫩枝,春、夏季剪下嫩枝,晒干或阴干,切成薄片或小段用。桂枝性温,味辛、甘,归心、肺、膀胱经,具有发汗解肌、温通经脉、助阳化气、平冲降气等功效,主要用于风寒感冒、脘腹冷痛、血寒经闭、关节痹痛、痰饮、水肿、心悸、奔豚等症。Among them, Guizhi is the dry twig of cinnamon, an evergreen tree plant of Lauraceae, which is cut off in spring and summer, dried in the sun or in the shade, and cut into thin slices or small sections for use. Guizhi is warm in nature, pungent and sweet in taste, and is directed to the heart, lung and bladder meridian. Amenorrhea due to cold, arthralgia, phlegm retention, edema, heart palpitations, embolism.
细辛,又名华细辛、细参、烟袋锅花,属马兜铃科多年生草本植物,为常用中药,因其根细、味辛,故得名。细辛性温,味辛,归肺、肾、心、肝、胆、脾经,具有温经散寒、化饮、祛风止痛等功效,主治风寒头痛、痰饮咳喘、风湿痹痛、牙痛、鼻渊等症。Asarum, also known as Asarum chinensis, Asarum chinensis, and Yandai pot flower, belongs to the perennial herb of Aristolochiaceae. It is a commonly used traditional Chinese medicine. It is named for its thin roots and pungent taste. Asarum is warm in nature and pungent in taste, and belongs to the lung, kidney, heart, liver, gallbladder, and spleen meridian. Syndrome etc.
白芷,又名薛、芷、芳香、苻蓠,为伞形科植物禹白芷、兴安白芷、川白芷、杭白芷或云南牛防风的根。白芷性温,味辛,归肺、胃经。具有解表散寒,祛风止痛,通鼻窍,燥湿止带,消肿排脓等功效。主要用于头痛,眉棱骨痛,齿痛,鼻渊,寒湿腹痛,肠风痔漏,赤白带下,痈疽疮疡,皮肤燥痒,疥癣等病症。Baizhi, also known as Xue, Zhi, Fangfang, Fujiao, is the root of Umbelliferae Yubaizhi, Xing'an Baizhi, Chuanbaizhi, Hangbaizhi or Yunnan Niufangfeng. Angelica dahurica is warm in nature, pungent in taste, and belongs to the lung and stomach meridians. It has the effects of relieving the exterior and dispelling cold, expelling wind and relieving pain, clearing the nasal orifice, drying dampness and stopping belt, reducing swelling and evacuating pus. Mainly used for headache, brow bone pain, toothache, nasal sinusitis, cold-damp abdominal pain, intestinal wind and hemorrhoids, red and white vaginal discharge, carbuncle sores, dry itchy skin, scabies and other diseases.
川芎,原名芎藭,为伞形科植物川芎的根茎。白芷味辛,性温,归肝、胆、心包经。具有活血行气,祛风止痛等功效。主要用于胸胁疼痛,风湿痹痛,症瘕结块,疮疡肿痛,跌扑伤痛,月经不调,经闭痛经,产后瘀痛,感冒头痛,偏正头痛等病症。Chuanxiong, formerly known as Xiongxue, is the rhizome of the Umbelliferae plant Chuanxiong. Angelica dahurica is pungent in taste, warm in nature, and returns to the liver, gallbladder, and pericardium meridians. It has the effects of promoting blood circulation and promoting qi, expelling wind and relieving pain. It is mainly used for chest and hypochondriac pain, rheumatism arthralgia, lumps in lumps, swelling and pain in sores, tumbling pain, irregular menstruation, amenorrhea dysmenorrhea, postpartum stasis, cold headache, migraine headache and other diseases.
红花,又称草红花,为菊科双子叶植物的干燥的管状花。红花具特异香气,性温,味辛,归心、肝经,具有活血通径、散瘀止痛等功效,主要用于经闭、痛经、恶露不行、症瘕痞块、跌打损伤等症。Safflower, also known as grass safflower, is a dry tubular flower of a dicotyledonous plant in the family Asteraceae. Safflower has a specific aroma, warm in nature, pungent in taste, heart-guiding, liver meridian, has the effects of promoting blood circulation, dispelling blood stasis, and relieving pain.
丹参,又名赤参,紫丹参,红根等,为双子叶植物唇形科,干燥根及根茎。丹参味苦,性微寒,归心、肝经。具有祛瘀止痛,活血通经,清心除烦,扩张血管等功效。主要用于月经不调,经闭痛经,癥瘕积聚,产后恶露,胸腹刺痛,肠鸣腹痛,热痹疼痛,疮疡肿痛,心烦不眠;肝脾肿大,心绞痛等病症。Salvia miltiorrhiza, also known as red ginseng, purple salvia miltiorrhiza, red root, etc., is a dicotyledonous plant Lamiaceae, dry root and rhizome. Salvia miltiorrhiza is bitter in taste, slightly cold in nature, and has the heart and liver meridians. It has the effects of dispelling blood stasis and relieving pain, promoting blood circulation and promoting menstrual flow, clearing heart-fire and eliminating troubles, and dilating blood vessels. Mainly used for irregular menstruation, amenorrhea dysmenorrhea, accumulation of lumps in the abdomen, postpartum lochia, chest and abdomen tingling, borborygmi and abdominal pain, heat arthralgia pain, sore swelling and pain, upset and insomnia; hepatosplenomegaly, angina pectoris and other diseases.
白芍,又名白花芍药,金芍药,为双子叶植物药毛茛科植物芍药(栽培种)的根。白芍性凉,味苦酸,归肝、脾经。具有养血柔肝,缓中止痛,敛阴收汗等功效。主要用于治胸腹胁肋疼痛,泻痢腹痛,自汗盗汗,阴虚发热,月经不调,崩漏,带下等病症。Radix Paeoniae Alba, also known as Radix Paeoniae Alba, Radix Paeoniae Alba, is the root of Radix Paeoniae Alba (cultivated species) of dicotyledonous herb Ranunculaceae. Radix Paeoniae Alba is cool in nature, bitter and sour in taste, and returns to the Liver and Spleen Channels. It has the effects of nourishing blood and softening the liver, relieving pain in the middle, astringing yin and sweating. It is mainly used to treat pain in the chest and abdomen, hypochondriac pain, diarrhea and abdominal pain, spontaneous sweating and night sweats, fever due to yin deficiency, irregular menstruation, uterine bleeding, leukorrhea and other diseases.
透骨草又名山野豌豆,落豆秧,山黑豆,为豆科植物山野豌豆的嫩茎叶。透骨草性温,味甘苦,具祛风湿,活血,舒筋,止痛等功效。主要用于治风湿痛,闪挫伤,无名肿毒,阴囊湿疹等病症。Speranium has another name called wild pea, falling bean seedling, and black bean, which are the tender stems and leaves of the leguminous plant wild pea. Herba Speranciae is warm in nature, sweet and bitter in taste, and has the effects of expelling rheumatism, promoting blood circulation, relaxing tendons, and relieving pain. It is mainly used to treat rheumatism, flash contusion, unknown swelling and poison, scrotum eczema and other diseases.
当归,又名秦归,云归,西当归,岷当归,为伞形科植物当归Angelicasinensis(Oliv.)Diels的根。当归性温,味甘、辛,归肝、心、脾经。具补血活血,调经止痛,润肠通便等功效。主要用于血虚萎黄、眩晕心悸、月经不调、经闭痛经、虚寒腹痛、肠燥便秘、风湿痹痛、跌扑损伤、痈疽疮疡等病症。Angelica, also known as Qingui, Yungui, West Angelica, Min Angelica, is the root of Umbelliferae Angelica sinensis (Oliv.) Diels. Angelica is warm in nature, sweet in taste, pungent, and returns to the Liver, Heart, and Spleen Meridians. It has the effects of nourishing blood and promoting blood circulation, regulating menstruation and relieving pain, moistening intestines and laxative. It is mainly used for blood deficiency and yellow complexion, dizziness and palpitations, irregular menstruation, amenorrhea dysmenorrhea, abdominal pain due to deficiency and cold, dryness of the intestine and constipation, rheumatic arthralgia, injury from falls, carbuncle sores and other diseases.
蔓荆子,又名白背木耳、白背杨、水捻子、白布荆,为马鞭草科植物单叶蔓荆的果实。蔓荆子性微寒,味辛、苦,归膀胱、肝、胃经。具疏散风热,清利头目等功效。主要用于风热感冒头痛、齿龈肿痛、目赤多泪、目暗不明、头晕目眩等病症。Vitex, also known as white-backed fungus, white-backed poplar, water twig, and white cloth vitex, is the fruit of Verbenaceae plant Vitex simplex. Vitex is slightly cold in nature, pungent and bitter in the mouth, and returns to the bladder, liver, and stomach meridians. It has the effects of evacuating wind-heat and clearing the head. It is mainly used for symptoms such as wind-heat cold, headache, swollen gums, red eyes and tears, dark eyes, dizziness and so on.
制川乌属川乌的炮制加工品,又名制鹅儿花、制铁花、制五毒。制川乌性热,味辛、苦,有大毒,归心、肝、肾、脾经。具有祛风除湿,温经止痛。用于风寒湿痹、关节疼痛、心腹冷痛、寒疝作痛等功效。主要用于治疗风寒湿痹、关节疼痛等病症。Zhichuanwu is a processed product of Chuanwu, also known as making goose flower, making iron flower, and making five poisons. Aconitum aconitum is hot in nature, pungent in taste, bitter, and highly poisonous, and is directed to the heart, liver, kidney, and spleen meridians. There is expelling wind and removing dampness, warming meridian and relieving pain. For anemofrigid-damp arthralgia, joint pain, confidant cold pain, cold colic pain and other effects. It is mainly used to treat diseases such as anemofrigid-damp arthralgia and joint pain.
制草乌属草乌的炮制加工品,又名制药羊蒿、制鸡头草、制百步草。制草乌性辛,味苦,归心、肝、肾、脾经。具祛风除湿,温经止痛等功效。主要用于风寒湿痹,关节疼痛,心腹冷痛,寒疝作痛,麻醉止痛等病症。Aconitum aconitum is a processed product of Aconitum aconitum, also known as Artemisia annua, Chicken head grass and Centipeda. Aconitum aconitum is pungent in nature, bitter in the mouth, GUIXIN, liver, kidney, spleen meridian. Tool expelling wind and dehumidification, warming meridians and relieving pain. It is mainly used for anemofrigid-damp arthralgia, arthralgia, confidant cold pain, cold colic pain, anesthesia and pain relief and other diseases.
埔姜籽,又名布惊籽、黄荆子、黄金子、布荆子、不惊籽,为马鞭草科植物黄荆Vitex negundo L.的果实。埔姜籽性温,味辛、苦,归肺、胃、肝经。具祛风解表,止咳平喘;理气消食止痛等功效。主伤风感冒、咳嗽、哮喘、胃痛吞酸、消化不良、食积泻痢、胆囊炎,胆结石、疝气等病症。用埔姜籽做枕芯的枕头具有舒筋活血、祛风除湿、清热解暑、防高血压、月日头风、颈椎增生、肩周炎、抗疲劳、改善睡眠等功效。它通风透气,散热快,且绝不会发霉,能使睡眠者凉爽舒适、消除烦燥。药籽的流动能按摩头、颈部,激活头、颈神筋,对颈椎病、一般性头晕头痛、类风湿性头晕头痛、产后头晕头痛等能起到辅助治疗的作用。Pujiangzi, also known as Bujingzi, Huangjingzi, Huangjinzi, Bujingzi, Bujingzi, is the fruit of Verbenaceae Vitex negundo L. Pu Jiangzi is warm in nature, pungent and bitter in taste, and returns to the lung, stomach and liver meridian. It has the effects of expelling wind and relieving exterior syndrome, relieving cough and relieving asthma, regulating qi, eliminating food and relieving pain. It is mainly used for colds, coughs, asthma, stomach pain, acid regurgitation, indigestion, dyspepsia, cholecystitis, gallstones, hernia and other diseases. Pillows made of ginger seeds have the functions of relaxing tendons and activating blood circulation, expelling wind and dampness, clearing heat and relieving heat, preventing high blood pressure, monthly head wind, cervical hyperplasia, frozen shoulder, anti-fatigue, and improving sleep. It is ventilated, heats up quickly, and will never be moldy, which can make the sleeper cool and comfortable, and eliminate irritability. The flow of the medicine seeds can massage the head and neck, activate the tendons of the head and neck, and play an auxiliary therapeutic role in cervical spondylosis, general dizziness and headache, rheumatoid dizziness and headache, and postpartum dizziness and headache.
合欢皮,又名合昏皮、夜台皮、合欢木皮,为豆科(Legumin0sae)植物合欢的干燥树皮。合欢皮味甘,平,归心、肝经。具安神解郁,活血消痈等功效。主要用于心神不安,忧郁失眠,肺痈疮肿,跌扑伤痛等病症。Albizia bark, also known as Albizia bark, Yetai bark, and Albizia bark, is the dry bark of Albizia julibrissin of the leguminous family (Legumin0sae). The bark of Albizia Julibrissin is sweet in taste, flat, GUIXIN, Liver Meridian. It has the effects of calming the nerves and relieving depression, promoting blood circulation and eliminating carbuncle. Mainly used for restlessness, depression, insomnia, lung abscess, sores, pain from falls and other diseases.
本发明中所述的桂枝、细辛、白芷、川芎、红花、丹参、白芍、透骨草、伸筋草、当归、蔓荆子、制川乌、制草乌、埔姜籽、合欢皮是本领域技术人员公知的,可以通过商业途径从医药商店购买得到或通过现有技术中公开的方法栽培、采收得到,其规格符合国家或行业标准即可。同时所用药材均无毒,长期服用药物依赖性小,且价格低廉,适合普通消费者使用。Guizhi, Asarum, Angelica dahurica, Rhizoma Chuanxiong, Safflower, Salvia, Paeoniae Alba, Sperantosporum, Radix Sinensis, Angelica, Vitex, Aconitum Aconitum, Aconitum Aconitum, Ginger Seed, The bark of Albizia juliensis is well known to those skilled in the art, and can be purchased commercially from medical stores or cultivated and harvested by methods disclosed in the prior art, and its specifications can meet national or industry standards. At the same time, the medicinal materials used are non-toxic, the drug dependence is small after long-term use, and the price is low, which is suitable for ordinary consumers.
作为优选,本发明所述中药组合物,由如下重量份原料制成:As a preference, the traditional Chinese medicine composition of the present invention is made of the following raw materials in parts by weight:
桂枝60份 细辛80份 白芷60份 川芎80份Guizhi 60 parts Asarum 80 parts Angelica dahurica 60 parts Chuanxiong 80 parts
红花50份 丹参150份 白芍150份 透骨草150份50 parts of safflower 150 parts of salvia miltiorrhiza 150 parts of white peony
伸筋草150份 当归50份 蔓荆子300份 制川乌80份150 parts of Shenjincao, 50 parts of Angelica, 300 parts of Vitex, 80 parts of Sichuan Aconitum
制草乌80份 埔姜籽300份 合欢皮150份。Make 80 parts of Aconitum, 300 parts of Pujiang Seed, and 150 parts of Albizia Juan.
本发明还提供了所述中药组合物的制备方法。The invention also provides a preparation method of the traditional Chinese medicine composition.
一种预防和治疗颈椎病的中药组合物的制备方法,为取55~65重量份桂枝,65~85重量份细辛,140~160重量份伸筋草,65~85重量份川芎,45~55重量份红花,140~160重量份丹参,140~160重量份白芍,140~160重量份透骨草,65~85重量份白芷,45~55重量份当归,290~310重量份蔓荆子,75~85重量份制川乌,75~85重量份制草乌,290~310重量份埔姜籽和140~160重量份合欢皮捣烂,过50~100目筛即得。A preparation method of a traditional Chinese medicine composition for preventing and treating cervical spondylosis. ~55 parts by weight of safflower, 140~160 parts by weight of Salvia miltiorrhiza, 140~160 parts by weight of Radix Paeoniae Alba, 140~160 parts by weight of Sperantosporum, 65~85 parts by weight of Angelica dahurica, 45~55 parts by weight of angelica, 290~310 parts by weight Vitex, 75-85 parts by weight to make Aconitum aconitum, 75-85 parts by weight to make Aconitum aconitum, 290-310 parts by weight to make ginger seed and 140-160 parts by weight to mash acacia bark, and pass through a 50-100-mesh sieve.
本发明还提供了所述中药组合物的临床制剂。本领域技术人员可以根据不同患者的需求将本发明所述中药组合物加入制备不同剂型是所需的各种药学上常规的辅料,如崩解剂、润滑剂、乳化剂、粘合剂等,以常规中药制剂方法,经常规加工直接或间接的加入药学上的可接受的辅料制成常用制剂。The invention also provides the clinical preparation of the traditional Chinese medicine composition. Those skilled in the art can add the traditional Chinese medicine composition of the present invention according to the needs of different patients and prepare various pharmaceutical conventional adjuvants required for different dosage forms, such as disintegrants, lubricants, emulsifiers, binders, etc. With conventional traditional Chinese medicine preparation methods, conventional processing is directly or indirectly added with pharmaceutically acceptable excipients to make common preparations.
优选的,本发明所述中药组合物的临床制剂为膏药,易于使用,针对性强,疗效明显。Preferably, the clinical preparation of the traditional Chinese medicine composition of the present invention is plaster, which is easy to use, highly targeted and has obvious curative effect.
本发明的药物组合物的使用剂量和使用方法取决于诸多因素,包括患者的年龄、体重、性别、自然健康状况、营养状况、化合物的活性强度、使用时间、代谢速率、病程严重程度以及诊治医师的主观判断。本领域的技术人员根据上述因素可以容易地决定药物组合物的使用剂量和使用方法。The dose and method of use of the pharmaceutical composition of the present invention depend on many factors, including the patient's age, body weight, sex, natural health status, nutritional status, activity intensity of the compound, use time, metabolic rate, severity of the course of the disease, and the treating physician subjective judgment. Those skilled in the art can easily determine the dosage and method of use of the pharmaceutical composition according to the above factors.
本发明还提供了包含本发明所述中药组合物的保健品。The invention also provides health care products comprising the traditional Chinese medicine composition of the invention.
优选的,本发明所述中药组合物的保健品为保健枕。Preferably, the health product of the traditional Chinese medicine composition of the present invention is a health pillow.
本发明还提供了所述保健枕的制备方法。The invention also provides a preparation method of the health-care pillow.
一种治疗预防和治疗颈椎病的保健枕的制备方法,将本发明所述中药组合物装入制好的布袋中封口,固定于枕芯表面即得。A preparation method of a health-care pillow for treating, preventing and curing cervical spondylosis. The traditional Chinese medicine composition of the present invention is packed into a prepared cloth bag, sealed, and fixed on the surface of the pillow.
其中,所述枕芯可以为本领域目前常见的不同材料的填充物,如荞麦壳、谷糠、棉等。Wherein, the pillow core can be filled with different materials commonly used in this field, such as buckwheat husk, rice bran, cotton and the like.
本发明经临床疗效观察,用本发明所述中药组合物治疗,治疗一个疗程症状明显减轻,两个疗程后症状全部消失,表明本发明所述中药组合物疗效显著。在231例颈椎病患者中,用本发明所述中药组合物保健枕治疗,治疗显效率为85.2%,有效率为97.0%,表明本发明所述治疗颈椎病的中药组合物保健枕疗效显著。在所治疗的患者中没有一例出现不良反应,表明本发明所述中药组合物对人体安全无毒。According to the clinical curative effect observation of the present invention, the symptoms are obviously alleviated after one course of treatment, and all symptoms disappear after two courses of treatment, which shows that the traditional Chinese medicine composition of the present invention has remarkable curative effect. Among 231 patients with cervical spondylosis, the curative effect was 85.2% and the effective rate was 97.0% with the Chinese medicine composition health-care pillow of the present invention, showing that the Chinese medicine composition health-care pillow for the treatment of cervical spondylosis of the present invention has a significant curative effect. No adverse reaction occurs in the treated patients, indicating that the traditional Chinese medicine composition of the present invention is safe and nontoxic to human body.
本发明提供了一种预防和治疗颈椎病的中药组合物。本发明所述中药组合物由桂枝、细辛、白芷、川芎、红花、丹参、白芍、透骨草、伸筋草、当归、蔓荆子、制川乌、制草乌、埔姜籽、合欢皮为原料制备而成,具有活血化瘀,舒筋通络,祛风止痛、软化血管之功效,对颈椎病、动脉硬化均有和很好的疗效,应用中医内病外治的原理,使病人不打针,不吃药,不按摩,不理疗,不去医院,不影响工作和学习而达到治病的目的。同时本发明所用药材均无毒,长期使用药物依赖性小,且价格低廉,适合短期及长期使用,具有广阔的市场前景。The invention provides a traditional Chinese medicine composition for preventing and treating cervical spondylosis. The traditional Chinese medicine composition of the present invention is composed of Guizhi, Asarum, Angelica dahurica, Chuanxiong, Safflower, Salvia, Radix Paeoniae Alba, Sperantosporum, Shenjincao, Angelica, Vitex, Zhichuanwu, Zhicaowu, Pujiang It has the functions of promoting blood circulation and removing blood stasis, relaxing tendons and collaterals, dispelling wind and relieving pain, and softening blood vessels. It has good curative effects on cervical spondylosis and arteriosclerosis. The principle is to prevent patients from taking injections, taking medicine, massage, physical therapy, going to the hospital, and without affecting work and study, so as to achieve the purpose of curing diseases. Simultaneously, the medicinal materials used in the invention are non-toxic, have little drug dependence for long-term use, are cheap, are suitable for short-term and long-term use, and have broad market prospects.
具体实施方式Detailed ways
本发明实施例公开了一种预防和治疗颈椎病的中药组合物及其制备方法。本领域技术人员可以借鉴本文内容,适当改进工艺参数实现。特别需要指出的是,所有类似的替换和改动对本领域技术人员来说是显而易见的,它们都被视为包括在本发明。本发明的方法已经通过较佳实施例进行了描述,相关人员明显能在不脱离本发明内容、精神和范围内对本文所述的方法进行改动或适当变更与组合,来实现和应用本发明技术。The embodiment of the invention discloses a traditional Chinese medicine composition for preventing and treating cervical spondylosis and a preparation method thereof. Those skilled in the art can refer to the content of this article to appropriately improve the process parameters to achieve. In particular, it should be pointed out that all similar replacements and modifications are obvious to those skilled in the art, and they are all considered to be included in the present invention. The method of the present invention has been described through preferred embodiments, and relevant personnel can obviously make changes or appropriate changes and combinations to the method described herein without departing from the content, spirit and scope of the present invention to realize and apply the technology of the present invention .
为了进一步理解本发明,下面结合实施例对本发明提供进行详细说明。In order to further understand the present invention, the present invention will be described in detail below in conjunction with the examples.
实施例1:本发明所述治疗颈椎病的中药组合物Embodiment 1: the Chinese medicine composition for the treatment of cervical spondylosis according to the present invention
所述中药组合物是由如下原料药制成:桂枝55g,细辛85g,伸筋草140g,川芎85g,红花45g,丹参160g,白芍140g,透骨草160g,白芷65g,当归55g,蔓荆子290g,制川乌85,制草乌75g,埔姜籽310g,合欢皮140g。The traditional Chinese medicine composition is made from the following raw materials: 55g of cassia twigs, 85g of asarum, 140g of radix chinensis, 85g of chuanxiong, 45g of safflower, 160g of salvia miltiorrhiza, 140g of white peony root, 160g of Speranthema, 65g of angelica, 55g of angelica , Vitex 290g, Zhichuan Aconitum 85, Zhicaowu 75g, Pu Jiangzi 310g, Albizia bark 140g.
制备方法为取上述药物在常温下按重量配比筛选混合后粉碎,过50~100目筛即得。The preparation method is that the above-mentioned drugs are screened and mixed according to the weight ratio at normal temperature, and then pulverized, and passed through a 50-100 mesh sieve to obtain the product.
实施例2:本发明所述治疗颈椎病的中药组合物Embodiment 2: the Chinese medicine composition for the treatment of cervical spondylosis according to the present invention
所述中药组合物是由如下原料药制成:桂枝65g,细辛65g,伸筋草160g,川芎65g,红花55g,丹参140g,白芍160g,透骨草140g,白芷85g,当归45g,蔓荆子310g,制川乌75,制草乌85g,埔姜籽290g,合欢皮160g。The traditional Chinese medicine composition is made from the following raw materials: 65g of cassia twigs, 65g of asarum, 160g of herba chinensis, 65g of chuanxiong, 55g of safflower, 140g of salvia miltiorrhiza, 160g of white peony root, 140g of Speranthema radix, 85g of angelica, 45g of angelica , Vitex 310g, Zhichuan Aconitum 75g, Zhicaowu 85g, Pujiang Seed 290g, Albizia Bark 160g.
制备方法为取上述药物在常温下按重量配比筛选混合后粉碎,过50~100目筛即得。The preparation method is that the above-mentioned drugs are screened and mixed according to the weight ratio at normal temperature, and then pulverized, and passed through a 50-100 mesh sieve to obtain the product.
实施例3:本发明所述治疗颈椎病的中药组合物Embodiment 3: the Chinese medicinal composition for the treatment of cervical spondylosis according to the present invention
所述中药组合物是由如下原料药制成:桂枝60g,细辛80g,白芷60g,川芎80g,红花50g,丹参150g,白芍150g,透骨草150g,伸筋草150g,当归50g,蔓荆子300g,制川乌80g,制草乌80g,埔姜籽300g,合欢皮150g。The traditional Chinese medicine composition is made from the following raw materials: 60g of cassia twig, 80g of Asarum, 60g of Angelica dahurica, 80g of Rhizoma Chuanxiong, 50g of safflower, 150g of salvia miltiorrhiza, 150g of white peony, 150g of Speranthema, 150g of Shenjincao, 50g of angelica , Vitex 300g, Aconitum 80g, Aconitum 80g, Ginger seeds 300g, Albizia bark 150g.
制备方法为上述药物在常温下按重量配比筛选混合后粉碎,过50~100目筛即得。The preparation method is that the above-mentioned drugs are screened and mixed according to the weight ratio at normal temperature, and then pulverized, and passed through a 50-100 mesh sieve to obtain the product.
实施例4:本发明所述治疗颈椎病的膏药Embodiment 4: the plaster for the treatment of cervical spondylosis according to the present invention
取实施例3所得的中药组合物用香油炸枯,再与成膏调料混合调制即得本发明所述治疗颈椎病的膏药。Get the Chinese medicinal composition gained in Example 3 and fry it dry with sesame oil, then mix it with the plaster seasoning to obtain the plaster for treating cervical spondylosis according to the present invention.
实施例5:本发明所述治疗颈椎病的保健枕Embodiment 5: the health-care pillow for treating cervical spondylosis according to the present invention
取实施例3所得的中药组合物装入制好的布袋中封口,固定在七孔棉枕芯表面即得。每个布袋长50cm、宽30cm,每个布袋装药末200g。Get the Chinese medicine composition gained in Example 3 and pack into the prepared cloth bag and seal it, and fix it on the surface of the seven-hole cotton pillow core to get final product. Each cloth bag is 50cm long and 30cm wide, and each cloth bag is filled with 200g of powdered medicine.
实施例6:本发明所述膏药治疗颈椎病临床试验报告Embodiment 6: plaster treatment cervical spondylosis clinical trial report of the present invention
病例1、王XX,编织工人,患有颈椎综合症,经常头晕,肩背酸涨,严重时,上肢及手部麻木,耳鸣眼花。到过多家医院就诊,有口服药,也有外用的膏药,效果均不明显。后来贴用本发明膏药,一个疗程症状明显减轻,两个疗程后症状全部消失。Case 1. Wang XX, a weaving worker, suffered from cervical spondylosis, often dizzy, sore shoulders and back, and in severe cases, numb upper limbs and hands, tinnitus and vertigo. I have gone to many hospitals to see a doctor, and there are oral medicines and plasters for external use, but the effect is not obvious. Paste plaster of the present invention afterwards, and a course of treatment symptom obviously alleviates, and after two courses of treatment, symptom all disappears.
病例2、帅XX,男,36岁,患有颈椎综合症、腰椎增生等。多方寻求治疗方法,但效果欠佳。贴用本发明膏药一个疗程后,症状明显减轻,两个疗程后症状全部消失。Case 2, handsome XX, male, 36 years old, suffering from cervical syndrome, lumbar hyperplasia, etc. Various methods of treatment have been sought, but the effect is not satisfactory. After sticking the plaster of the present invention for one course of treatment, the symptoms obviously alleviated, and after two courses of treatment, the symptoms all disappeared.
实施例7:本发明所述保健枕治疗颈椎病临床试验报告。Embodiment 7: Clinical trial report on the treatment of cervical spondylosis by the health-care pillow of the present invention.
选择门诊或病房的病例231例,男121例,女110例,年龄界于29~78岁,病程最短14天,最长26年。其中颈型18例,占7.8%;神经根型80例,占34.6%;颈动脉型63例,占27.3%;交感神经型20例,占8.7%,脊髓型21例,占9%;混合型29例,占12.6%。231 cases were selected from outpatient clinic or ward, including 121 males and 110 females, aged from 29 to 78 years old, with the shortest duration of 14 days and the longest duration of 26 years. Among them, there were 18 cases of cervical type, accounting for 7.8%; 80 cases of nerve root type, accounting for 34.6%; 63 cases of carotid type, accounting for 27.3%; 20 cases of sympathetic type, accounting for 8.7%, 21 cases of spinal cord type, accounting for 9%; Type 29 cases, accounting for 12.6%.
治疗前X线表现:所有患者常规摄颈椎四位片,必要时加开口位、过屈侧位,均有不同程度的骨关节病理改变。X-ray manifestations before treatment: All patients routinely took four-view cervical spine films, and if necessary, added mouth and hyperflexed lateral views. All patients had pathological changes in bone and joints to varying degrees.
治疗方法:使用本发明实施例5所述中药组合物保健枕,连续使用2个月,期间停止使用其他中西药及保健品。Therapeutic method: use the traditional Chinese medicine composition health-care pillow described in the embodiment of the present invention 5, use continuously for 2 months, stop using other Chinese and western medicines and health products during this period.
治疗结果:治愈197例,占85.2%;有效27例,占11.7%;无效7例,占3.0%。Treatment results: 197 cases were cured, accounting for 85.2%; 27 cases were effective, accounting for 11.7%; 7 cases were ineffective, accounting for 3.0%.
以上实施例的说明只是用于帮助理解本发明的方法及其核心思想。应当指出,对于本技术领域的普通技术人员来说,在不脱离本发明原理的前提下,还可以对本发明进行若干改进和修饰,这些改进和修饰也落入本发明权利要求的保护范围内。The descriptions of the above embodiments are only used to help understand the method and core idea of the present invention. It should be pointed out that for those skilled in the art, without departing from the principle of the present invention, some improvements and modifications can be made to the present invention, and these improvements and modifications also fall within the protection scope of the claims of the present invention.
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| CN1146343A (en) * | 1995-09-25 | 1997-04-02 | 石建民 | External compress paste for discopathy |
| CN101061975A (en) * | 2007-06-01 | 2007-10-31 | 王珉 | Medicine mat for preventing and treating cervical vertebrae diseases |
| CN102125672A (en) * | 2010-01-12 | 2011-07-20 | 姚玉健 | Traditional Chinese medicine for treating cervical and lumbar spinal diseases and preparation method thereof |
| CN102462747A (en) * | 2010-11-15 | 2012-05-23 | 乔宁祖 | External application bag for lumbar diseases |
-
2012
- 2012-10-25 CN CN201210411805.6A patent/CN102940736B/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1146343A (en) * | 1995-09-25 | 1997-04-02 | 石建民 | External compress paste for discopathy |
| CN101061975A (en) * | 2007-06-01 | 2007-10-31 | 王珉 | Medicine mat for preventing and treating cervical vertebrae diseases |
| CN102125672A (en) * | 2010-01-12 | 2011-07-20 | 姚玉健 | Traditional Chinese medicine for treating cervical and lumbar spinal diseases and preparation method thereof |
| CN102462747A (en) * | 2010-11-15 | 2012-05-23 | 乔宁祖 | External application bag for lumbar diseases |
Non-Patent Citations (4)
| Title |
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| 刘绍慧.药枕治颈椎病.《农村百事通》.2007,(第14期),全文. |
| 药枕治颈椎病;刘绍慧;《农村百事通》;20070710(第14期);全文 * |
| 颈椎病;黄佳仁;《健康生活》;20070401(第04期);全文 * |
| 黄佳仁.颈椎病.《健康生活》.2007,(第04期),全文. |
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| CN102940736A (en) | 2013-02-27 |
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Address after: 523000 Guangdong City, Fenggang Town, Tong Tong Village, Phoenix Industrial Zone, No. 7 plant Patentee after: DONGGUAN YALU SMART HOME CO., LTD. Address before: 523000 Guangdong Province, Dongguan city Fenggang town youganpu South Industrial Zone Patentee before: Dongguan City Yaroo Home Textile Product Co., Ltd. |
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