CN103550593B - Medicament for treating chilblain - Google Patents
Medicament for treating chilblain Download PDFInfo
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- CN103550593B CN103550593B CN201310561361.9A CN201310561361A CN103550593B CN 103550593 B CN103550593 B CN 103550593B CN 201310561361 A CN201310561361 A CN 201310561361A CN 103550593 B CN103550593 B CN 103550593B
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- herba
- medicament
- chilblain
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- 239000003814 drug Substances 0.000 title claims abstract description 24
- 208000010445 Chilblains Diseases 0.000 title claims abstract description 17
- 241001349804 Juncus alpinoarticulatus Species 0.000 claims abstract description 5
- 240000008022 Rauvolfia verticillata Species 0.000 claims abstract description 5
- 244000042295 Vigna mungo Species 0.000 claims abstract description 5
- 235000010716 Vigna mungo Nutrition 0.000 claims abstract description 5
- 235000011453 Vigna umbellata Nutrition 0.000 claims abstract description 5
- 239000000463 material Substances 0.000 claims abstract description 4
- 241000628997 Flos Species 0.000 claims description 8
- 210000000582 semen Anatomy 0.000 claims description 8
- 244000025254 Cannabis sativa Species 0.000 claims description 4
- 241000533849 Gleditsia Species 0.000 claims description 4
- 240000002853 Nelumbo nucifera Species 0.000 claims description 4
- 235000006508 Nelumbo nucifera Nutrition 0.000 claims description 4
- 235000006510 Nelumbo pentapetala Nutrition 0.000 claims description 4
- 244000175269 Smilax herbacea Species 0.000 claims description 4
- 244000269722 Thea sinensis Species 0.000 claims description 4
- 230000000694 effects Effects 0.000 abstract description 4
- 241000234282 Allium Species 0.000 abstract 1
- 241000330736 Bauhinia championii Species 0.000 abstract 1
- 240000002791 Brassica napus Species 0.000 abstract 1
- 235000011293 Brassica napus Nutrition 0.000 abstract 1
- 235000000540 Brassica rapa subsp rapa Nutrition 0.000 abstract 1
- 235000010520 Canavalia ensiformis Nutrition 0.000 abstract 1
- 235000010518 Canavalia gladiata Nutrition 0.000 abstract 1
- 241000084370 Catalpa bungei Species 0.000 abstract 1
- 241000688694 Cheilanthes argentea Species 0.000 abstract 1
- 244000022372 Diospyros lotus Species 0.000 abstract 1
- 235000003333 Diospyros lotus Nutrition 0.000 abstract 1
- 240000001723 Entada phaseoloides Species 0.000 abstract 1
- 240000001771 Euonymus fortunei Species 0.000 abstract 1
- 241000931143 Gleditsia sinensis Species 0.000 abstract 1
- 240000007860 Heteropogon contortus Species 0.000 abstract 1
- 244000048199 Hibiscus mutabilis Species 0.000 abstract 1
- 235000003973 Hibiscus mutabilis Nutrition 0.000 abstract 1
- 241001571736 Lysimachia foenum-graecum Species 0.000 abstract 1
- 241001139545 Mallotus apelta Species 0.000 abstract 1
- 235000010804 Maranta arundinacea Nutrition 0.000 abstract 1
- 244000100135 Melanthera biflora Species 0.000 abstract 1
- 244000062730 Melissa officinalis Species 0.000 abstract 1
- 235000010654 Melissa officinalis Nutrition 0.000 abstract 1
- 241000672236 Petrocosmea duclouxii Species 0.000 abstract 1
- 241000725605 Pilea notata Species 0.000 abstract 1
- 240000000103 Potentilla erecta Species 0.000 abstract 1
- 235000016551 Potentilla erecta Nutrition 0.000 abstract 1
- 241000220317 Rosa Species 0.000 abstract 1
- 244000207852 Salomonia cantoniensis Species 0.000 abstract 1
- 240000006694 Stellaria media Species 0.000 abstract 1
- 241000145969 Streptolirion volubile Species 0.000 abstract 1
- 241001247808 Stylophorum lasiocarpum Species 0.000 abstract 1
- 241001232424 Symphyotrichum subulatum Species 0.000 abstract 1
- 244000145580 Thalia geniculata Species 0.000 abstract 1
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- 239000004615 ingredient Substances 0.000 abstract 1
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- 238000011282 treatment Methods 0.000 description 7
- 229940079593 drug Drugs 0.000 description 4
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- 230000036772 blood pressure Effects 0.000 description 3
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- 208000003251 Pruritus Diseases 0.000 description 2
- 206010047700 Vomiting Diseases 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
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- 208000002173 dizziness Diseases 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 230000019612 pigmentation Effects 0.000 description 2
- 206010040882 skin lesion Diseases 0.000 description 2
- 231100000444 skin lesion Toxicity 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
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- 239000002671 adjuvant Substances 0.000 description 1
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- 230000003203 everyday effect Effects 0.000 description 1
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- 230000003902 lesion Effects 0.000 description 1
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a medicament for treating chilblain. The medicament for treating the chilblain is prepared from the following raw materials in parts by weight: allium caelureum, sword bean, arrowroot, rose, Chinese alpine rush, all-grass of annual saltmarsh aster, lysimachia foenum-graecum, bauhinia championii, manchurian catalpa bark, stylophorum lasiocarpum, cinquefoil, parietaria root, axillary balm herb, assorted Chinese herbal tea, rauvolfia verticillata, petrocosmea duclouxii, mallotus apelta, heteropogon contortus, streptolirion volubile, hibiscus mutabilis, turnip, aleuritopteris argentea fee, dindygulen peperoni herb, wintercreeper, prostrate wedelia, salomonia cantoniensis lour, Chinese honey locust, rice bean, pilea notata and diospyros lotus. All the ingredients of the medicament for treating the chilblain are natural materials, the safety is high, and the curative effect is clear and definite, so that the medicament for treating the chilblain is applicable to large-scale clinical popularization.
Description
Technical field
The present invention relates to department of dermatologry field, relate in particular to a kind of medicament for the treatment of chilblain.
Background technology
Chilblain is the limitation Inflammatory Lesions because cold causes.Chilblain is the commonly encountered diseases in winter, and according to relevant statistics, China has 200,000,000 people to be subject to the puzzlement of chilblain every year, wherein mainly child, women and old people.Chilblain, once occur, normal more difficult rapid healing in cold season, just can heal after day cyclostrophic be waited warm gradually.
Summary of the invention
The object of this invention is to provide a kind of medicament for the treatment of chilblain.
In order to realize object of the present invention, the invention provides a kind of medicament for the treatment of chilblain, it is made up of the material of following weight proportioning: blue Jacob's ladder 8 parts, Semen Canavaliae 9 parts, Rhizoma Marantae arundinaceae 9 parts, the Flos rosae multiflorae 5 parts, Chinese alpine rush 8 parts, auspicious even grass 9 parts, Herba Lysimachiae foenum-graeci 3 parts, Caulis Bauhihiae Championii 5 parts, Cortex catalpae bungei 3 parts, Herba Stylophori Lasiocapi 5 parts, 6 parts, cliff lotus, Radix parietariae micranthae 3 parts, Herba melissae axillaris 3 parts, assorted Chinese medicine tea 2 parts, Rauvolfia verticillata 5 parts, Herba Hylotelephii Mingjiniani 2 parts, Folium Malloti Apeltae 5 parts, Radix seu herba Heteropogonis Contorti 8 parts, Folium Bambusae 7 parts, Flos Hibisci Mutabilis 8 parts, Radix Brassicae rapae 9 parts, Radix et Rhizoma Iridis Sanguineae 3 parts, Semen Sojae Preparatum 72 parts, Caulis Seu Folium Euonymi Fortunei 5 parts, Herba Wedeliae Prostratae 6 parts, Herba Salomoniae Cantoniensis 3 parts, 7 parts, Fructus Gleditsia, rice bean 8 parts, Rhizoma Belamcandae 3 parts and Fructus Dispyroris Loti 6 parts.
More preferably, described medicament can be tablet, dispersible tablet, capsule or decoction.
In order to understand the present invention better, with reference to " Chinese medicine voluminous dictionary " second edition, being described as follows of some crude drug used in the present invention:
In the present compositions, blue Jacob's ladder, Semen Canavaliae, Rhizoma Marantae arundinaceae, the Flos rosae multiflorae, Chinese alpine rush are monarch drug; Auspicious even grass, Herba Lysimachiae foenum-graeci, Caulis Bauhihiae Championii, Cortex catalpae bungei, Herba Stylophori Lasiocapi, cliff lotus, Radix parietariae micranthae, Herba melissae axillaris are ministerial drug; Assorted Chinese medicine tea, Rauvolfia verticillata, Herba Hylotelephii Mingjiniani, Folium Malloti Apeltae, Radix seu herba Heteropogonis Contorti, Folium Bambusae, Flos Hibisci Mutabilis, Radix Brassicae rapae, Radix et Rhizoma Iridis Sanguineae, Semen Sojae Preparatum seven, Caulis Seu Folium Euonymi Fortunei are adjuvant drug; Herba Wedeliae Prostratae, Herba Salomoniae Cantoniensis, Fructus Gleditsia, rice bean, Rhizoma Belamcandae and Fructus Dispyroris Loti are for making medicine; Compositions of the present invention plays drug effect best by monarch synergism.
Whole compositions of the medicament for the treatment of chilblain of the present invention are all natural materials, and safety is better, and clear curative effect, is suitable for large-scale promotion clinically.
Detailed description of the invention
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are for illustration of the present invention instead of limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.Unless otherwise stated, the percent in the present invention is percetage by weight.
Embodiment decoction of the present invention
Take blue Jacob's ladder 8 grams, Semen Canavaliae 9 grams, Rhizoma Marantae arundinaceae 9 grams, the Flos rosae multiflorae 5 grams, Chinese alpine rush 8 grams, auspicious even grass 9 grams, Herba Lysimachiae foenum-graeci 3 grams, Caulis Bauhihiae Championii 5 grams, Cortex catalpae bungei 3 grams, Herba Stylophori Lasiocapi 5 grams, 6 grams, cliff lotus, Radix parietariae micranthae 3 grams, Herba melissae axillaris 3 grams, assorted Chinese medicine tea 2 grams, Rauvolfia verticillata 5 grams, Herba Hylotelephii Mingjiniani 2 grams, Folium Malloti Apeltae 5 grams, Radix seu herba Heteropogonis Contorti 8 grams, Folium Bambusae 7 grams, Flos Hibisci Mutabilis 8 grams, Radix Brassicae rapae 9 grams, Radix et Rhizoma Iridis Sanguineae 3 grams, Semen Sojae Preparatum 72 grams, Caulis Seu Folium Euonymi Fortunei 5 grams, Herba Wedeliae Prostratae 6 grams, Herba Salomoniae Cantoniensis 3 grams, 7 grams, Fructus Gleditsia, rice bean 8 grams, Rhizoma Belamcandae 3 grams and Fructus Dispyroris Loti 6 grams, add 6000 milliliters, water, heat 5 hours at 90 DEG C in the flask that condensing tube is housed, filter, filtrate is decoction of the present invention.
Experimental example
Patient data
In 60 routine patients, man 30 example, female 30 example; 17 years old-34 years old age.According to " combination of Chinese and Western medicine dermatological " [M]. the 2nd edition (Bian Tianyu, Tianjin science tech publishing house, 1996.313-314) judges chilblain.In 60 routine patients, chilblain occupies the majority from the beginning of the swollen pain person that itches, and the person of festering occupies the minority; Send out in hands, face person majority, middle toe and heel portion person minority.Fall ill the shortest 5 days.The longest 20 days.
Therapeutic Method
The decoction of preparation in embodiment 1 is used to treat.Every day 1 time, oral 100 milliliters at every turn, treatment 7 days continuously.
Efficacy assessment standard
Cure: skin recovers normal or has pigmentation; Effective: skin lesion place major part disappears to tie and is crazy about, and pruritus due to heat sense alleviates gradually; Effective: all diseases have to be taken a turn for the better in various degree; Invalid: skin lesion is without any change.
Result
Treat and find after 7 days, the skin of 60 routine patients recovers normal or has pigmentation, therefore all meets the efficacy assessment standard of healing.
Untoward reaction and toxic and side effects monitoring
By detect patient blood pressure, pulse, whether there is Nausea and vomiting, dizzy clinical symptoms judges untoward reaction.Setting human normal systolic pressure is between 90-140mmHg, diastolic pressure is between 60-90mmHg, human normal pulse is 60-100 beat/min, blood pressure, the pulse of patient is measured at treatments period, find that the blood pressure and pulse recorded is all within normal range, the phenomenon not exceeding normal interval occurs, and does not occur Nausea and vomiting, dizzy clinical symptoms.This illustrates that pharmaceutical composition of the present invention does not have obvious untoward reaction, and then proves that this medicine does not have obvious toxic and side effects for human body.
Claims (1)
1. treat the medicament of chilblain for one kind, it is characterized in that, it is made up of the material of following weight proportioning: blue Jacob's ladder 8 parts, Semen Canavaliae 9 parts, Rhizoma Marantae arundinaceae 9 parts, the Flos rosae multiflorae 5 parts, Chinese alpine rush 8 parts, auspicious even grass 9 parts, Herba Lysimachiae foenum-graeci 3 parts, Caulis Bauhihiae Championii 5 parts, Cortex catalpae bungei 3 parts, Herba Stylophori Lasiocapi 5 parts, 6 parts, cliff lotus, Radix parietariae micranthae 3 parts, Herba melissae axillaris 3 parts, assorted Chinese medicine tea 2 parts, Rauvolfia verticillata 5 parts, Herba Hylotelephii Mingjiniani 2 parts, Folium Malloti Apeltae 5 parts, Radix seu herba Heteropogonis Contorti 8 parts, Folium Bambusae 7 parts, Flos Hibisci Mutabilis 8 parts, Radix Brassicae rapae 9 parts, Radix et Rhizoma Iridis Sanguineae 3 parts, Semen Sojae Preparatum 72 parts, Caulis Seu Folium Euonymi Fortunei 5 parts, Herba Wedeliae Prostratae 6 parts, Herba Salomoniae Cantoniensis 3 parts, 7 parts, Fructus Gleditsia, rice bean 8 parts, Rhizoma Belamcandae 3 parts and Fructus Dispyroris Loti 6 parts.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310561361.9A CN103550593B (en) | 2013-11-12 | 2013-11-12 | Medicament for treating chilblain |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310561361.9A CN103550593B (en) | 2013-11-12 | 2013-11-12 | Medicament for treating chilblain |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103550593A CN103550593A (en) | 2014-02-05 |
| CN103550593B true CN103550593B (en) | 2015-04-15 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310561361.9A Expired - Fee Related CN103550593B (en) | 2013-11-12 | 2013-11-12 | Medicament for treating chilblain |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103550593B (en) |
-
2013
- 2013-11-12 CN CN201310561361.9A patent/CN103550593B/en not_active Expired - Fee Related
Non-Patent Citations (1)
| Title |
|---|
| 中医对冻疮的辨证论治;万海栋等;《亚太传统医药》;20100630;第6卷(第6期);第52-53页 * |
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| Publication number | Publication date |
|---|---|
| CN103550593A (en) | 2014-02-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| ASS | Succession or assignment of patent right |
Owner name: XU BIN Free format text: FORMER OWNER: ZHENG HAIYAN Effective date: 20150311 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| C53 | Correction of patent for invention or patent application | ||
| CB03 | Change of inventor or designer information |
Inventor after: Xu Bin Inventor before: Zheng Haiyan |
|
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 272100 JINING, SHANDONG PROVINCE TO: 273500 JINING, SHANDONG PROVINCE Free format text: CORRECT: INVENTOR; FROM: ZHENG HAIYAN TO: XU BIN |
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| TA01 | Transfer of patent application right |
Effective date of registration: 20150311 Address after: Department of general surgery, General Hospital of Jining City, Zoucheng City, Shandong province 273500 kangfulu No. 2 Yankuang Group Co. Ltd. Applicant after: Xu Bin Address before: 272100 Department of Dermatology, first people's Hospital, 6 health Road, Shandong, Jining, China Applicant before: Zheng Haiyan |
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| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20150415 Termination date: 20151112 |
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| EXPY | Termination of patent right or utility model |