CN106963777A - 一种“黄芩苷‑小檗碱”复合物的制备方法及其应用 - Google Patents
一种“黄芩苷‑小檗碱”复合物的制备方法及其应用 Download PDFInfo
- Publication number
- CN106963777A CN106963777A CN201710242030.7A CN201710242030A CN106963777A CN 106963777 A CN106963777 A CN 106963777A CN 201710242030 A CN201710242030 A CN 201710242030A CN 106963777 A CN106963777 A CN 106963777A
- Authority
- CN
- China
- Prior art keywords
- jamaicin
- scutelloside
- compound
- preparation
- solvent medium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Description
Claims (9)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710242030.7A CN106963777B (zh) | 2017-04-14 | 2017-04-14 | 一种“黄芩苷-小檗碱”复合物的制备方法及其应用 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710242030.7A CN106963777B (zh) | 2017-04-14 | 2017-04-14 | 一种“黄芩苷-小檗碱”复合物的制备方法及其应用 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN106963777A true CN106963777A (zh) | 2017-07-21 |
CN106963777B CN106963777B (zh) | 2020-07-14 |
Family
ID=59332950
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710242030.7A Expired - Fee Related CN106963777B (zh) | 2017-04-14 | 2017-04-14 | 一种“黄芩苷-小檗碱”复合物的制备方法及其应用 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN106963777B (zh) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108743601A (zh) * | 2018-07-06 | 2018-11-06 | 江苏大学 | 一种抗溃疡性结肠炎的黄芩苷-黄芩素组合物及其制剂 |
CN111686186A (zh) * | 2020-06-24 | 2020-09-22 | 杭州巴洛特生物科技有限公司 | 一种美沙拉嗪口服液的生产工艺 |
CN115154475A (zh) * | 2022-05-24 | 2022-10-11 | 中国医学科学院北京协和医院 | 一种纳米复合物、其制备方法及其应用 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101411717A (zh) * | 2008-11-07 | 2009-04-22 | 北京宏泰康达医药科技有限公司 | 一种治疗急性肠炎和痢疾的组合物 |
-
2017
- 2017-04-14 CN CN201710242030.7A patent/CN106963777B/zh not_active Expired - Fee Related
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101411717A (zh) * | 2008-11-07 | 2009-04-22 | 北京宏泰康达医药科技有限公司 | 一种治疗急性肠炎和痢疾的组合物 |
Non-Patent Citations (3)
Title |
---|
JING-RONG WANG, ET AL.: "Formation and Conformation of Baicalin–Berberine and Wogonoside–Berberine Complexes", 《CHEM. PHARM. BULL.》 * |
孙磊 等: "黄芩苷-盐酸小檗碱复合物的溶解度与油水分配系数测定", 《中国实验方剂学杂志》 * |
胡律江 等: "黄连与黄芩配伍时主要有效成分溶出率变化规律研究", 《中华中医药杂志(原中国医药学报)》 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108743601A (zh) * | 2018-07-06 | 2018-11-06 | 江苏大学 | 一种抗溃疡性结肠炎的黄芩苷-黄芩素组合物及其制剂 |
CN111686186A (zh) * | 2020-06-24 | 2020-09-22 | 杭州巴洛特生物科技有限公司 | 一种美沙拉嗪口服液的生产工艺 |
CN115154475A (zh) * | 2022-05-24 | 2022-10-11 | 中国医学科学院北京协和医院 | 一种纳米复合物、其制备方法及其应用 |
Also Published As
Publication number | Publication date |
---|---|
CN106963777B (zh) | 2020-07-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2022042428A1 (zh) | 人参皂苷Rg3与Rg5的组合物及其抗肿瘤等药用 | |
WO2021120972A1 (zh) | 一种治疗气血两虚症候的中药组合物及其制备方法和应用 | |
CN104922176B (zh) | 一种野菊花提取物的应用 | |
CN1947757B (zh) | 地黄叶提取物及其制备方法和用途、用该提取物制备的药物 | |
CN106963777A (zh) | 一种“黄芩苷‑小檗碱”复合物的制备方法及其应用 | |
CN113143997A (zh) | 桑提取物在制备减轻动物体重的药物中的应用 | |
CN104432063A (zh) | 一种缓解运动性疲劳的组合物及其制剂 | |
CN107551001B (zh) | 一种用于防治酒精性肝损伤的中药复合物及其制法 | |
CN112274547A (zh) | 一种含有水飞蓟提取物和1,6二磷酸果糖的组合物及其在护肝、醒酒、抗疲劳中的应用 | |
US9445624B2 (en) | Anti-fatigue composition of plant material and preparation method, use and products thereof | |
CN108420890B (zh) | 一种具有降血脂作用的组合物及其制备方法 | |
CN101024066A (zh) | 金嗓利咽制剂及其制备方法 | |
CN102526230A (zh) | 一种治疗肝病的中药组合物、其制备方法和质量检测方法及应用 | |
CN101024060B (zh) | 金嗓散结制剂的制备方法 | |
WO2014134833A1 (zh) | 可食用组合物及其制备方法和包含该组合物的食品 | |
CN106928376A (zh) | 山茱萸多糖的分离方法及其应用 | |
CN102949681B (zh) | 一种预防或治疗感冒的组合物及其制备方法 | |
CN107997170B (zh) | 一种具有降血脂功能的组合物及其制备方法 | |
CN102727867B (zh) | 一种抗肿瘤用药物组合物及应用、试剂盒及包装件 | |
RU2812611C1 (ru) | Композиции из гинзенозида Rg3 и гинзенозида Rg5 и их фармацевтическое применение, включая противоопухолевые эффекты | |
CN112057476B (zh) | 一种组合物及其在醒酒解宿醉护胃上的应用 | |
CN102836315A (zh) | 一种预防调理转归肿瘤的中药组合物及其制备方法 | |
CN108042595B (zh) | 一种具有保健功能的组合物及其制备方法和应用 | |
CN100482245C (zh) | 板蓝根和黄芩苷的药物组合物 | |
KR100885671B1 (ko) | 항당뇨 천연물복합제의 마이크로캡슐화 방법 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
CB03 | Change of inventor or designer information | ||
CB03 | Change of inventor or designer information |
Inventor after: Wang Wenping Inventor after: Sun Lei Inventor after: Shi Bowen Inventor after: Lei Yanli Inventor after: Su Hong Inventor after: Lei Yaya Inventor after: Zhang Xia Inventor after: Feng Jun Inventor before: Wang Wenping Inventor before: Sun Lei Inventor before: Lei Yanli Inventor before: Su Hong Inventor before: Lei Yaya Inventor before: Zhang Xia Inventor before: Feng Jun |
|
GR01 | Patent grant | ||
GR01 | Patent grant | ||
CB03 | Change of inventor or designer information | ||
CB03 | Change of inventor or designer information |
Inventor after: Wang Wenping Inventor after: Sun Lei Inventor after: Shi Bowen Inventor after: Lei Yanli Inventor after: Su Hong Inventor after: Lei Yaya Inventor after: Zhang Xia Inventor after: Feng Jun Inventor before: Wang Wenping Inventor before: Sun Lei Inventor before: Lei Yanli Inventor before: Su Hong Inventor before: Lei Yaya Inventor before: Zhang Xia Inventor before: Feng Jun |
|
CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20200714 |