CN106955403A - 一种闭环吸入麻醉控制系统 - Google Patents
一种闭环吸入麻醉控制系统 Download PDFInfo
- Publication number
- CN106955403A CN106955403A CN201710186910.7A CN201710186910A CN106955403A CN 106955403 A CN106955403 A CN 106955403A CN 201710186910 A CN201710186910 A CN 201710186910A CN 106955403 A CN106955403 A CN 106955403A
- Authority
- CN
- China
- Prior art keywords
- anesthesia
- closed loop
- control system
- inhalation
- vaporization
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 206010002091 Anaesthesia Diseases 0.000 title claims abstract description 106
- 230000037005 anaesthesia Effects 0.000 title claims abstract description 106
- 230000029058 respiratory gaseous exchange Effects 0.000 claims abstract description 44
- 238000009834 vaporization Methods 0.000 claims abstract description 36
- 230000008016 vaporization Effects 0.000 claims abstract description 36
- 239000003193 general anesthetic agent Substances 0.000 claims abstract description 31
- 238000004891 communication Methods 0.000 claims abstract description 21
- 239000003983 inhalation anesthetic agent Substances 0.000 claims abstract description 20
- 239000003814 drug Substances 0.000 claims abstract description 17
- 238000012377 drug delivery Methods 0.000 claims abstract description 11
- 230000003444 anaesthetic effect Effects 0.000 claims description 16
- 238000012806 monitoring device Methods 0.000 claims description 9
- 210000004556 brain Anatomy 0.000 claims description 8
- 238000002347 injection Methods 0.000 claims description 8
- 239000007924 injection Substances 0.000 claims description 8
- PIWKPBJCKXDKJR-UHFFFAOYSA-N Isoflurane Chemical compound FC(F)OC(Cl)C(F)(F)F PIWKPBJCKXDKJR-UHFFFAOYSA-N 0.000 claims description 7
- 229960002725 isoflurane Drugs 0.000 claims description 7
- 229920006395 saturated elastomer Polymers 0.000 claims description 6
- GQPLMRYTRLFLPF-UHFFFAOYSA-N Nitrous Oxide Chemical compound [O-][N+]#N GQPLMRYTRLFLPF-UHFFFAOYSA-N 0.000 claims description 5
- 239000000835 fiber Substances 0.000 claims description 5
- DPYMFVXJLLWWEU-UHFFFAOYSA-N desflurane Chemical compound FC(F)OC(F)C(F)(F)F DPYMFVXJLLWWEU-UHFFFAOYSA-N 0.000 claims description 4
- 229960003537 desflurane Drugs 0.000 claims description 4
- 230000000763 evoking effect Effects 0.000 claims description 4
- 229960003132 halothane Drugs 0.000 claims description 3
- BCQZXOMGPXTTIC-UHFFFAOYSA-N halothane Chemical compound FC(F)(F)C(Cl)Br BCQZXOMGPXTTIC-UHFFFAOYSA-N 0.000 claims description 3
- 238000004458 analytical method Methods 0.000 claims description 2
- 238000001514 detection method Methods 0.000 claims description 2
- 229910052731 fluorine Inorganic materials 0.000 claims description 2
- 239000011737 fluorine Substances 0.000 claims description 2
- -1 fluorine Alkane Chemical class 0.000 claims description 2
- 238000010438 heat treatment Methods 0.000 claims description 2
- 238000002604 ultrasonography Methods 0.000 claims description 2
- 238000009423 ventilation Methods 0.000 claims description 2
- 229940079593 drug Drugs 0.000 abstract description 8
- 239000007789 gas Substances 0.000 description 32
- 238000012544 monitoring process Methods 0.000 description 22
- 239000000126 substance Substances 0.000 description 9
- 229960002078 sevoflurane Drugs 0.000 description 8
- DFEYYRMXOJXZRJ-UHFFFAOYSA-N sevoflurane Chemical compound FCOC(C(F)(F)F)C(F)(F)F DFEYYRMXOJXZRJ-UHFFFAOYSA-N 0.000 description 8
- 230000000694 effects Effects 0.000 description 6
- 238000001802 infusion Methods 0.000 description 6
- 238000005516 engineering process Methods 0.000 description 5
- 208000002193 Pain Diseases 0.000 description 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 4
- 230000005611 electricity Effects 0.000 description 4
- 229910052760 oxygen Inorganic materials 0.000 description 4
- 239000001301 oxygen Substances 0.000 description 4
- 238000012545 processing Methods 0.000 description 4
- 238000011160 research Methods 0.000 description 4
- 230000036387 respiratory rate Effects 0.000 description 4
- 206010039897 Sedation Diseases 0.000 description 3
- 230000036592 analgesia Effects 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 230000037396 body weight Effects 0.000 description 3
- 238000003745 diagnosis Methods 0.000 description 3
- 230000000857 drug effect Effects 0.000 description 3
- 239000011551 heat transfer agent Substances 0.000 description 3
- 238000001727 in vivo Methods 0.000 description 3
- 210000004072 lung Anatomy 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 230000036407 pain Effects 0.000 description 3
- 230000036280 sedation Effects 0.000 description 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- 238000001949 anaesthesia Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 238000009835 boiling Methods 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- JPGQOUSTVILISH-UHFFFAOYSA-N enflurane Chemical compound FC(F)OC(F)(F)C(F)Cl JPGQOUSTVILISH-UHFFFAOYSA-N 0.000 description 2
- 229960000305 enflurane Drugs 0.000 description 2
- 230000000004 hemodynamic effect Effects 0.000 description 2
- 230000005764 inhibitory process Effects 0.000 description 2
- 238000001990 intravenous administration Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 229960002455 methoxyflurane Drugs 0.000 description 2
- RFKMCNOHBTXSMU-UHFFFAOYSA-N methoxyflurane Chemical compound COC(F)(F)C(Cl)Cl RFKMCNOHBTXSMU-UHFFFAOYSA-N 0.000 description 2
- 230000002232 neuromuscular Effects 0.000 description 2
- 239000001272 nitrous oxide Substances 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 206010067484 Adverse reaction Diseases 0.000 description 1
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 1
- 208000003870 Drug Overdose Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 206010021118 Hypotonia Diseases 0.000 description 1
- 208000036647 Medication errors Diseases 0.000 description 1
- 206010033296 Overdoses Diseases 0.000 description 1
- 235000008331 Pinus X rigitaeda Nutrition 0.000 description 1
- 235000011613 Pinus brutia Nutrition 0.000 description 1
- 241000018646 Pinus brutia Species 0.000 description 1
- 208000003443 Unconsciousness Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 210000000133 brain stem Anatomy 0.000 description 1
- 210000005013 brain tissue Anatomy 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 210000003169 central nervous system Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000001054 cortical effect Effects 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 231100000725 drug overdose Toxicity 0.000 description 1
- 210000001061 forehead Anatomy 0.000 description 1
- 238000002695 general anesthesia Methods 0.000 description 1
- 239000002869 intravenous anesthetic agent Substances 0.000 description 1
- 238000010253 intravenous injection Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000005399 mechanical ventilation Methods 0.000 description 1
- 230000036640 muscle relaxation Effects 0.000 description 1
- 239000003158 myorelaxant agent Substances 0.000 description 1
- 229960001730 nitrous oxide Drugs 0.000 description 1
- 230000001473 noxious effect Effects 0.000 description 1
- 238000011022 operating instruction Methods 0.000 description 1
- 230000003285 pharmacodynamic effect Effects 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- OLBCVFGFOZPWHH-UHFFFAOYSA-N propofol Chemical compound CC(C)C1=CC=CC(C(C)C)=C1O OLBCVFGFOZPWHH-UHFFFAOYSA-N 0.000 description 1
- 229960004134 propofol Drugs 0.000 description 1
- 238000013139 quantization Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 210000004761 scalp Anatomy 0.000 description 1
- 230000036259 sexual stimuli Effects 0.000 description 1
- 238000001629 sign test Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 238000004448 titration Methods 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 210000004291 uterus Anatomy 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/01—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes specially adapted for anaesthetising
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
- A61M16/10—Preparation of respiratory gases or vapours
- A61M16/14—Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
- A61M16/18—Vaporising devices for anaesthetic preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/40—Respiratory characteristics
- A61M2230/43—Composition of exhalation
- A61M2230/437—Composition of exhalation the anaesthetic agent concentration
Landscapes
- Health & Medical Sciences (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
Description
Claims (9)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710186910.7A CN106955403A (zh) | 2017-03-15 | 2017-03-15 | 一种闭环吸入麻醉控制系统 |
PCT/CN2018/079045 WO2018166481A1 (zh) | 2017-03-15 | 2018-03-14 | 一种闭环吸入麻醉控制系统 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201710186910.7A CN106955403A (zh) | 2017-03-15 | 2017-03-15 | 一种闭环吸入麻醉控制系统 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN106955403A true CN106955403A (zh) | 2017-07-18 |
Family
ID=59470360
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201710186910.7A Pending CN106955403A (zh) | 2017-03-15 | 2017-03-15 | 一种闭环吸入麻醉控制系统 |
Country Status (2)
Country | Link |
---|---|
CN (1) | CN106955403A (zh) |
WO (1) | WO2018166481A1 (zh) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2018166481A1 (zh) * | 2017-03-15 | 2018-09-20 | 重庆奥基医药科技有限公司 | 一种闭环吸入麻醉控制系统 |
CN110368559A (zh) * | 2019-07-24 | 2019-10-25 | 泸州市中医医院(泸州市中西医结合医院、泸州市江阳区中医医院) | 用于呼吸道的雾化麻醉系统 |
CN111281598A (zh) * | 2020-03-05 | 2020-06-16 | 纳菲(深圳)制药科技有限公司 | 麻醉控制系统及方法 |
US20200327995A1 (en) * | 2017-12-29 | 2020-10-15 | Shenzhen Mindray Bio-Medical Electronics Co., Ltd. | Method for identifying anesthetic drug, and method and device for processing anesthesia electroencephalogram signal |
CN113230511A (zh) * | 2021-05-25 | 2021-08-10 | 四川大学华西医院 | 一种靶控给药装置 |
CN114129825A (zh) * | 2021-11-12 | 2022-03-04 | 上海市第六人民医院 | 一种智能麻醉控制系统 |
CN116531628A (zh) * | 2023-06-13 | 2023-08-04 | 大庆油田总医院 | 一种智能麻醉呼吸安全监控系统及方法 |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP4048343A4 (en) * | 2019-10-24 | 2023-12-06 | The Trustees of Columbia University in the City of New York | SYSTEM, METHOD AND COMPUTER-ACCESSIBLE MEDIUM FOR VISUALIZATION AND ANALYSIS OF ELECTROENCEPHALOGRAM OSCILLATIONS IN THE ALPHA BAND |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN2885297Y (zh) * | 2005-03-25 | 2007-04-04 | 郑方 | 全紧闭自动控制麻醉机 |
US20100241064A1 (en) * | 2007-10-15 | 2010-09-23 | The Secretary, Department Of Information Technology | Automatic Anaesthesia Delivery System |
CN203556030U (zh) * | 2013-11-14 | 2014-04-23 | 柏安平 | 一种新型多功能麻醉机 |
CN203898880U (zh) * | 2014-06-13 | 2014-10-29 | 李永胜 | 移动式麻醉机 |
CN105963843A (zh) * | 2016-04-15 | 2016-09-28 | 杨建勇 | 一种智能麻醉蒸发装置 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106955403A (zh) * | 2017-03-15 | 2017-07-18 | 中国人民解放军第三军医大学第二附属医院 | 一种闭环吸入麻醉控制系统 |
-
2017
- 2017-03-15 CN CN201710186910.7A patent/CN106955403A/zh active Pending
-
2018
- 2018-03-14 WO PCT/CN2018/079045 patent/WO2018166481A1/zh active Application Filing
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN2885297Y (zh) * | 2005-03-25 | 2007-04-04 | 郑方 | 全紧闭自动控制麻醉机 |
US20100241064A1 (en) * | 2007-10-15 | 2010-09-23 | The Secretary, Department Of Information Technology | Automatic Anaesthesia Delivery System |
CN203556030U (zh) * | 2013-11-14 | 2014-04-23 | 柏安平 | 一种新型多功能麻醉机 |
CN203898880U (zh) * | 2014-06-13 | 2014-10-29 | 李永胜 | 移动式麻醉机 |
CN105963843A (zh) * | 2016-04-15 | 2016-09-28 | 杨建勇 | 一种智能麻醉蒸发装置 |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2018166481A1 (zh) * | 2017-03-15 | 2018-09-20 | 重庆奥基医药科技有限公司 | 一种闭环吸入麻醉控制系统 |
US20200327995A1 (en) * | 2017-12-29 | 2020-10-15 | Shenzhen Mindray Bio-Medical Electronics Co., Ltd. | Method for identifying anesthetic drug, and method and device for processing anesthesia electroencephalogram signal |
CN110368559A (zh) * | 2019-07-24 | 2019-10-25 | 泸州市中医医院(泸州市中西医结合医院、泸州市江阳区中医医院) | 用于呼吸道的雾化麻醉系统 |
CN111281598A (zh) * | 2020-03-05 | 2020-06-16 | 纳菲(深圳)制药科技有限公司 | 麻醉控制系统及方法 |
CN111281598B (zh) * | 2020-03-05 | 2023-12-08 | 纳菲(深圳)制药科技有限公司 | 麻醉控制系统及方法 |
CN113230511A (zh) * | 2021-05-25 | 2021-08-10 | 四川大学华西医院 | 一种靶控给药装置 |
CN114129825A (zh) * | 2021-11-12 | 2022-03-04 | 上海市第六人民医院 | 一种智能麻醉控制系统 |
CN114129825B (zh) * | 2021-11-12 | 2024-02-27 | 上海市第六人民医院 | 一种智能麻醉控制系统 |
CN116531628A (zh) * | 2023-06-13 | 2023-08-04 | 大庆油田总医院 | 一种智能麻醉呼吸安全监控系统及方法 |
CN116531628B (zh) * | 2023-06-13 | 2023-12-29 | 大庆油田总医院 | 一种智能麻醉呼吸安全监控系统及方法 |
Also Published As
Publication number | Publication date |
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WO2018166481A1 (zh) | 2018-09-20 |
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Legal Events
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PB01 | Publication | ||
PB01 | Publication | ||
TA01 | Transfer of patent application right | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20171107 Address after: Chongqing city Shapingba District 400037 Bridge Street No. 183 Applicant after: No.2 Hospital Attached to No.3 Military Medical College, PLA Applicant after: Chongqing Auki Medical Technology Co Ltd Address before: Chongqing city Shapingba District 400037 Bridge Street No. 183 Applicant before: No.2 Hospital Attached to No.3 Military Medical College, PLA Applicant before: Chongqing Source Medical Technology Co., Ltd. |
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CI02 | Correction of invention patent application |
Correction item: Applicant|Address|Applicant Correct: No.2 Hospital Attached to No.3 Military Medical College, PLA|Chongqing city Shapingba District 400037 Bridge Street No. 183|Chongqing Source Medical Technology Co., Ltd. False: No.2 Hospital Attached to No.3 Military Medical College, PLA|Chongqing city Shapingba District 400037 Bridge Street No. 183|Chongqing Auki Medical Technology Co Ltd Number: 47-02 Volume: 33 |
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TA01 | Transfer of patent application right |
Effective date of registration: 20171215 Address after: Chongqing city Shapingba District 400037 Bridge Street No. 183 Applicant after: No.2 Hospital Attached to No.3 Military Medical College, PLA Applicant after: Chongqing Auki Medical Technology Co Ltd Address before: Chongqing city Shapingba District 400037 Bridge Street No. 183 Applicant before: No.2 Hospital Attached to No.3 Military Medical College, PLA Applicant before: Chongqing Source Medical Technology Co., Ltd. |
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TA01 | Transfer of patent application right | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20180213 Address after: 400039 Chongqing Jiulongpo Branch City Road No. 166, building 67, No. 2-1 Applicant after: Chongqing Auki Medical Technology Co Ltd Address before: Chongqing city Shapingba District 400037 Bridge Street No. 183 Applicant before: No.2 Hospital Attached to No.3 Military Medical College, PLA Applicant before: Chongqing Auki Medical Technology Co Ltd |
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TA01 | Transfer of patent application right |
Effective date of registration: 20190327 Address after: 404100 No. 83 Xinqiao Zhengjie, Shapingba District, Chongqing Applicant after: The Second Affiliated Hospital of PLA Military Medical University Address before: 400039 No. 2-1, Building 67, 166 Kecheng Road, Jiulongpo District, Chongqing Applicant before: Chongqing Auki Medical Technology Co Ltd |
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