CN106924328A - A kind of excellent careless nutritional preparation and its production method of escaping of prevention of cardiovascular disease - Google Patents

A kind of excellent careless nutritional preparation and its production method of escaping of prevention of cardiovascular disease Download PDF

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Publication number
CN106924328A
CN106924328A CN201710254886.6A CN201710254886A CN106924328A CN 106924328 A CN106924328 A CN 106924328A CN 201710254886 A CN201710254886 A CN 201710254886A CN 106924328 A CN106924328 A CN 106924328A
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parts
escaping
prevention
raw material
cardiovascular disease
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杨品红
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Hunan University of Arts and Science
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Hunan University of Arts and Science
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Priority to CN201710254886.6A priority Critical patent/CN106924328A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/41Crassulaceae (Stonecrop family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Zoology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of excellent careless nutritional preparation of escaping of prevention of cardiovascular disease, mainly it is prepared from by the raw material of following weight portion:It is excellent escape grass 20 30 parts, rescue 10 15 parts of heart dish, 8 10 parts of Sambucus thunbergiana, 58 parts of ginseng, 8 10 parts of safflower, 38 parts of konjaku powder.Excellent grass of escaping of the invention used, to rescue heart dish, ginseng, safflower etc. direct-edible, and people is had no side effect, and effectively disposes endovascular rubbish(Such as fats), recover blood vessel elasticity, can improve systemic blood flow state, strengthen cardiac contractility ability, improve blood pressure, effect is clearly in terms of prevention of cardiovascular disease.

Description

A kind of excellent careless nutritional preparation and its production method of escaping of prevention of cardiovascular disease
Technical field
The present invention relates to the technical field of nourishment of prevention of cardiovascular disease, and in particular to a kind of prevention of cardiovascular disease Excellent shield grass nutritional preparation and its production method.
Background technology
Angiocardiopathy, is a series of to be related to the disease of the circulatory system, common disease to have hat also known as circulation system disease Worry, angina pectoris, myocardial infarction etc., but it is general all relevant with artery sclerosis.Angiocardiopathy changes in the presence of a common pathology Become, be related to atherosclerosis and thrombosis, atherosclerosis is that the lesion in arterial blood tube wall occurs, and beginning first has interior Film is thickened, lipidosis, cellular infiltration, middle film smooth muscle cell to tube chamber shift and rise in value, then cell extracellular matrix hyperplasia and There is foam cells, arterial wall is become rotten athero- structure, rupture or thrombosis finally occur, cause tube chamber to block and blood supply Obstacle.In recent years, the morbidity and mortality of cardiovascular and cerebrovascular disease are in rising trend, and angiocardiopathy is mainly to treat It is defined, but its prevention takes highly important status.
Excellent grass of escaping, category Lamiales, Acanthaceae, crocodile mouth flower category, be one kind be grown in by equatorial low altitude area sparse woods or A kind of tall and big herbaceous plant in shrubbery in moist sandy soil, the maturity period is generally 3-9 month, its nature and flavor is sweet, pungent, slight bitter, It is mild-natured, enter liver and kidney channel.Complete stool is used as medicine, the effect such as clearing heat and detoxicating, eliminating stasis to subdue swelling, anti-inflammatory are relieved the effect of alcohol, cancer-resisting, can improve whole body Blood flow state, strengthens cardiac contractility ability, improves blood pressure, and containing rich in protein, nutritive value is high.It is conventionally used to treatment Ephritis, nephrarctia, kidney failure, kidney stone, it is also possible to treat throat swell and ache, hepatitis, jaundice, skin disease, hypertension, high fat of blood, Hyperglycaemia, gastritis, arthralgia pain due to rheumatism, and have good therapeutic effect to kinds cancer.
Rescue heart dish, also known as take dish, rescue heart dish and contain various medicinal ingredients, such as red-spotted stonecrop is sweet, paddy steroid acid oleanolic acid, acetone, Flavones, several amino acids and vitamin, its flat property and sweet taste, with promoting blood circulation and removing blood stasis, nourishing heart soothing the liver, calm the nerves enrich blood, it is clearing heat and detoxicating it Effect, is common broad-spectrum green herbal medicine among the people, and former plant is also one of antitumor Chinese herbal medicine.Verified through expert clinical:It is edible to rescue the heart The dish several months can suppress and treat hypertensive heart disease (coronary heart disease, arrhythmia cordis, paroxysmal tachycardia, rheumatic heart disease Deng), play the role of calming heart soothing the liver, calm the nerves enrich blood, clearing heat and detoxicating, hemostasia and dissipation blood stasis, can prevent and treat hysteria, artery sclerosis, hemiplegia, Insomnia and dreamful sleep, palpitaition are nervous, high fat of blood, diabetes, thrombocytopenic purpura, bleeding gums, hyper-menorrhea, traumatic injury, More than the ten kinds of cardiovascular and cerebrovascular disease such as hepatitis, hemorrhage of digestive tract, it is therefore named to rescue heart dish.Rescue heart dish form grace, clean taste, medicine tableware It is good, can be fried with meat egg edible mushroom dried shrimps etc., stewed, can Baoshang, faric, mutton cooked in a chafing pot, also can element fry, it is cold and dressed with sauce, be stained with sauce, pickled pickles, Its unique flavor, hundred eat and do not mind.
Sambucus thunbergiana, is medicinal plant, can control traumatic injury, have the effect of wind-damp dispelling, restore menstrual flow and invigorate blood circulation, detoxicating, relieving inflammation, herb It is used as medicine, root energy wind-dispelling detumescence is stimulated the circulation of the blood and cause the muscles and joints to relax, treating rheumatic arthritis, traumatic injury;Stem, leaf have sweating, diuresis, restore menstrual flow and invigorate blood circulation, Control the effect such as nephritic dropsy.
The content of the invention
For the deficiency that above-mentioned prior art is present, escaped it is an object of the invention to provide a kind of the excellent of prevention of cardiovascular disease Careless nutritional preparation and its production method.
To achieve the above object, one of the technical solution adopted by the present invention is:A kind of excellent grass of escaping of prevention of cardiovascular disease Nutritional preparation, is mainly prepared from by the raw material of following weight portion:It is excellent escape it is careless 20-30 parts, rescue 10-15 parts of heart dish, Sambucus thunbergiana 8- 10 parts, ginseng 5-8 parts, safflower 8-10 parts, konjaku powder 3-8 parts.
The excellent careless nutritional preparation of escaping of above-mentioned prevention of cardiovascular disease, also including the raw material of following weight portion:Soluble pearl Powder 3-5 parts.
The two of technical scheme are a kind of production methods of the excellent careless nutritional preparation of escaping of prevention of cardiovascular disease, its It is characterised by, comprises the following steps:
(1)The pretreatment of raw material:First by the excellent grass of escaping in raw material, heart dish, Sambucus thunbergiana, ginseng, safflower are rescued each by clear Wash, drain, dry after pulverize;Then the extraction for adding suitable quantity of water to be put under Ultrasonic Conditions after being stirred is mixed Carry out first adding cellulase in mixing extraction, extractor in tank, the addition of cellulase is 1000-3000U, Extracting temperature It it is 45-55 DEG C, the reaction time is 2-5h, then toward trypsase is added in extractor, the addition of cellulase is 500- 1500U, reaction temperature is 37 DEG C, and the reaction time is 3-6h, is then centrifuged for, and collects supernatant and sediment, standby;
(2)Advanced treating:To sediment colloid mill, probiotics is subsequently adding, the addition of probiotics is sediment gross weight 1-3%, after fermentation 3-5h, adds cellulase, and the addition of cellulase is 800-1500U, digests 2-4h, and centrifugation is received Collection supernatant;
(3)Finished product:By step(1)The supernatant and step for obtaining(2)The supernatant mixing for obtaining, adds remaining raw material, mixes Close uniform, you can be obtained.
Compared with prior art, the beneficial effect that possesses of the present invention is:1st, the present invention excellent grass of escaping used, rescue heart dish, ginseng, Safflower etc. is direct-edible, and people is had no side effect;2nd, by it is excellent escape grass, rescue heart dish, Sambucus thunbergiana etc. mutually compatibility, effectively dispose Endovascular rubbish(Such as fats), recover blood vessel elasticity, systemic blood flow state can be improved, strengthen cardiac contractility ability, improve Blood pressure, effect is clearly in terms of prevention of cardiovascular disease;3rd, in addition to having good preventive effect to angiocardiopathy, this hair Bright preparation also has beauty, promotes the effect such as wound healing and anticancer, can improve the resistivity of human body;4th, life of the invention Product method almost remains the nutritional ingredient and active component of more than the 90% of raw material, is of high nutritive value.
Specific embodiment
Presently in connection with specific embodiment, to be further elaborated to invention.
Embodiment one
The excellent careless oral formulations of escaping of prevention of cardiovascular disease, are prepared from by the raw material of following weight portion:It is excellent escape grass 30 parts, rescue the heart 10 parts of dish, 8 parts of Sambucus thunbergiana, 5 parts of ginseng, 8 parts of safflower, 8 parts of konjaku powder.
Production method, comprises the following steps:
(1)The pretreatment of raw material:First by the excellent grass of escaping in raw material, heart dish, Sambucus thunbergiana, ginseng, safflower are rescued each by clear Wash, drain, dry after pulverize;Then the extraction for adding suitable quantity of water to be put under Ultrasonic Conditions after being stirred is mixed Carry out first adding cellulase in mixing extraction, extractor in tank, Extracting temperature is 50 DEG C, and the reaction time is 5h, it is then past to carry Take and trypsase is added in tank, reaction temperature is 37 DEG C, and the reaction time is 6h, is then centrifuged for, collect supernatant and sediment, it is standby With;
(2)Advanced treating:To sediment colloid mill, probiotics is subsequently adding, the addition of probiotics is weight of precipitate 1-3%, after fermentation 3h, adds cellulase, digests 4h, and supernatant is collected in centrifugation;
(3)Finished product:By step(1)The supernatant and step for obtaining(2)The supernatant mixing for obtaining, and add after stevioside again plus Enter konjaku powder, be well mixed, you can finished product.
Embodiment two
The excellent careless oral formulations of escaping of prevention of cardiovascular disease, are prepared from by the raw material of following weight portion:It is excellent escape grass 20 parts, rescue the heart 15 parts of dish, 10 parts of Sambucus thunbergiana, 8 parts of ginseng, 10 parts of safflower, 3 parts of soluble pearl powder, 5 parts of konjaku powder.
Production method, comprises the following steps:
(1)The pretreatment of raw material:First by the excellent grass of escaping in raw material, heart dish, Sambucus thunbergiana, ginseng, safflower are rescued each by clear Wash, drain, dry after pulverize;Then the extraction for adding suitable quantity of water to be put under Ultrasonic Conditions after being stirred is mixed Carry out first adding cellulase in mixing extraction, extractor in tank, Extracting temperature is 45-55 DEG C, and the reaction time is 2-5h, then Trypsase is added toward extractor is interior, reaction temperature is 37 DEG C, and the reaction time is 3-6h, is then centrifuged for, and collects supernatant and sinks Starch, it is standby;
(2)Advanced treating:To sediment colloid mill, probiotics is subsequently adding, the addition of probiotics is weight of precipitate 1-3%, after fermentation 3-5h, adds cellulase, digests 2-4h, and supernatant is collected in centrifugation;
(3)Finished product:By step(1)The supernatant and step for obtaining(2)The supernatant mixing for obtaining, and add soluble pearl Powder, konjaku powder, are well mixed, you can be obtained.

Claims (3)

1. a kind of excellent careless nutritional preparation of escaping of prevention of cardiovascular disease, it is characterised in that the main raw material system by following weight portion It is standby to form:It is excellent escape it is careless 20-30 parts, rescue 10-15 parts of heart dish, Sambucus thunbergiana 8-10 parts, ginseng 5-8 parts, safflower 8-10 parts, konjaku powder 3-8 parts.
2. the excellent careless nutritional preparation of escaping of prevention of cardiovascular disease according to claim 1, it is characterised in that also including as follows The raw material of weight portion:Soluble pearl powder 3-5 parts.
3. the production method of the excellent careless nutritional preparation of escaping of prevention of cardiovascular disease according to claim 1 and 2, its feature exists In comprising the following steps:
(1)The pretreatment of raw material:First by the excellent grass of escaping in raw material, heart dish, Sambucus thunbergiana, ginseng, safflower are rescued each by clear Wash, drain, dry after pulverize;Then the extraction for adding suitable quantity of water to be put under Ultrasonic Conditions after being stirred is mixed Carry out first adding cellulase in mixing extraction, extractor in tank, Extracting temperature is 45-55 DEG C, and the reaction time is 2-5h, then Trypsase is added toward extractor is interior, reaction temperature is 37 DEG C, and the reaction time is 3-6h, is then centrifuged for, and collects supernatant and sinks Starch, it is standby;
(2)Advanced treating:To sediment colloid mill, probiotics is subsequently adding, after fermentation 3-5h, adds cellulase, enzymolysis Supernatant is collected in 2-4h, centrifugation;
(3)Finished product:By step(1)The supernatant and step for obtaining(2)The supernatant mixing for obtaining, and remaining raw material is added, mix Close uniform, you can be obtained.
CN201710254886.6A 2017-04-18 2017-04-18 A kind of excellent careless nutritional preparation and its production method of escaping of prevention of cardiovascular disease Pending CN106924328A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115844933A (en) * 2022-11-22 2023-03-28 海南医学院 Application of clinacanthus nutans total flavonoids in preparation of anti-heart failure drugs

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1709147A (en) * 2005-07-06 2005-12-21 郑弘� Dried powder of aizoon stonecrop herb
CN1726977A (en) * 2005-06-30 2006-02-01 郑弘� Vegetable complex liquid for heart resurrection

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1726977A (en) * 2005-06-30 2006-02-01 郑弘� Vegetable complex liquid for heart resurrection
CN1709147A (en) * 2005-07-06 2005-12-21 郑弘� Dried powder of aizoon stonecrop herb

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115844933A (en) * 2022-11-22 2023-03-28 海南医学院 Application of clinacanthus nutans total flavonoids in preparation of anti-heart failure drugs

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Application publication date: 20170707