CN106917147A - A kind of electrostatic spinning apparatus - Google Patents

Abstract

The invention discloses an electrospinning device, comprising: an AC high-voltage generator; a liquid supply device, including a micro-injection pump; a gas supply device; a nozzle, and the nozzle includes a liquid supply channel connected to the liquid supply device and a ring connected to the gas supply device. Shaped air supply channel, the air supply channel is sleeved on the outside of the liquid supply channel, the end of the outlet section of the liquid supply channel is a tapered tip, and the nozzle is connected to the AC high-voltage generator; the receiver includes at least two rod-shaped support arms , a rotating shaft and a transmission device for driving the rotating shaft to rotate. One end of the supporting arm is fixedly connected to the rotating shaft and the other end is suspended in the air. The adjacent supporting arms are arranged at intervals. When the rotating shaft rotates, all supporting arms form a bowl-shaped rotating surface. The liquid outlet and the air outlet are set oppositely. This kind of electrospinning device can form fibers with extremely small diameters. The fiber diameters are evenly distributed, the structure is fluffy, and the mechanical properties are superior. It can avoid the generation of recoil airflow, and can be widely used in the field of tissue engineering.

Description

An electrospinning device

technical field

The invention relates to the technical field of spinning, in particular to an electrostatic spinning device.

Background technique

In recent years, the technology in the field of tissue engineering has received high attention and in-depth research. The principle of tissue engineering is to induce and promote a series of physiological activities such as cell growth, migration and proliferation in vivo or in vitro, and finally form an organ with a three-dimensional structure. or organization. One such application is nanofibrous tissue engineering scaffolds.

At present, electrospinning is usually used to prepare nanofibrous tissue engineering scaffolds. In a typical production method, air-blown polymer solution is used to prepare nanofibers on a large scale. However, the diameter of air-spun fibers is relatively large, and traditional air-spun Closed receivers or cylindrical receivers are often used. Under the action of high-speed airflow, it is easy to generate recoil airflow, which affects the directional deposition of fibers.

Therefore, how to form fibers with an extremely small diameter and prevent backflushing airflow during the spinning process is a technical problem that those skilled in the art need to solve.

Contents of the invention

In view of this, the object of the present invention is to provide an electrospinning device capable of forming fibers with extremely small diameters and preventing backflushing airflow during the spinning process.

To achieve the above object, the present invention provides the following technical solutions:

An electrospinning device comprising:

AC high voltage generator;

Liquid supply devices, including micro-syringe pumps;

air supply device;

A spray head, the spray head includes a liquid supply channel connected to the liquid supply device and an annular air supply channel connected to the gas supply device, the air supply channel is sleeved on the outside of the liquid supply channel, the supply The end of the outlet section of the liquid channel is a tapered tip, and the nozzle is connected to the AC high-voltage generator;

The receiver includes at least two rod-shaped support arms, a rotating shaft and a transmission device for driving the rotating shaft to rotate, one end of the supporting arm is fixedly connected to the rotating shaft and the other end is suspended, and the adjacent supporting arms are arranged at intervals , all the support arms form a bowl-shaped rotating surface when the rotating shaft rotates, and the bowl-shaped rotating surface is arranged opposite to the liquid outlet and the air outlet of the spray head.

Preferably, the radial section of the liquid supply channel is circular, the radial section of the air supply channel is circular, and the air supply channel and the liquid supply channel are arranged coaxially, and the central axis is straight line.

Preferably, one end of the air supply channel in the axial direction is sealed and the other end is the air outlet, the middle part of the air supply channel in the axial direction protrudes radially outward on both sides, and the air supply The device is connected to the protrusion.

Preferably, the liquid supply channel sequentially includes an inlet section for placing a connecting pipe, a liquid storage section, and the outlet section along the axial direction, and the hole diameter of the inlet section is smaller than the hole diameter of the liquid storage section.

Preferably, the air supply device includes an air pressure supply device connected to the air supply channel through an air delivery pipe, a precision air pressure regulating valve provided on the air delivery pipe, and a heating device is provided in the inlet section.

Preferably, a temperature measuring device is provided on the liquid supply channel and the gas supply channel, and the temperature measuring device, the liquid supply device, the gas supply device and the heating device are respectively connected to a numerical control device.

Preferably, all the support arms are arranged at equal intervals.

Preferably, the support arm is a bent metal sheet or a bent metal rod or a bent plastic rod.

Preferably, one side of the receiver is provided with a gas guiding device for guiding the direction of gas flow, and the gas guiding device and the support arm are separately arranged on both sides in the axial direction of the rotating shaft.

In the electrospinning device provided by the present invention, a high-voltage electric field is formed between the receiver and the nozzle under the action of an AC high-voltage generator to provide an electric field for electrospinning. Air stretching and an airflow that assists in stretching the jet flow is formed between the nozzle and the receiver, so that fibers with extremely small diameters can be formed, and the fiber diameter distribution is uniform, the structure is fluffy, and the mechanical properties are superior; at the same time, the adjacent supporting wall There is a gap between them, which can effectively allow high-speed airflow to pass through and avoid the generation of recoil airflow; in addition, the electrospinning device can prepare a wide range of materials, stable process, good versatility, and can be widely used in the field of tissue engineering.

Description of drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following will briefly introduce the drawings that need to be used in the description of the embodiments or the prior art. Obviously, the accompanying drawings in the following description are only It is an embodiment of the present invention, and those skilled in the art can also obtain other drawings according to the provided drawings on the premise of not paying creative efforts.

Fig. 1 is the structural representation of the specific embodiment of electrospinning device provided by the present invention;

Fig. 2 is a schematic structural view of the nozzle in a specific embodiment of the electrospinning device provided by the present invention.

In Figure 1 and Figure 2, 1 is an AC high-voltage generator, 2 is a liquid supply device, 3 is an air supply device, 4 is a nozzle, 41 is an air outlet, 42 is a liquid outlet, 43 is an air supply channel, and 44 is a supply Liquid channel, 45 is a precise air pressure regulating valve, 5 is a receiver, 51 is a rotating shaft, 52 is a transmission device, and 53 is a support arm.

detailed description

The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

The core of the present invention is to provide an electrospinning device capable of forming fibers with extremely small diameters and preventing backflushing airflow during the spinning process.

Please refer to Fig. 1 and Fig. 2, Fig. 1 is a schematic structural diagram of a specific embodiment of an electrospinning device provided by the present invention; Fig. 2 is a schematic structural diagram of a nozzle in a specific embodiment of an electrospinning device provided by the present invention.

A specific embodiment of the electrospinning device provided by the present invention includes an AC high voltage generator 1 , a liquid supply device 2 , an air supply device 3 , a nozzle 4 and a receiver 5 . The control system in the AC high voltage generator 1 controls the voltage output of the AC high voltage generator 1 . The liquid supply device 2 includes a micro-injection pump, and the liquid supply device 2 can send the spinning solution or melt into the liquid supply channel 44 of the spray head 4 and flow out from the liquid outlet 42 of the liquid supply channel 44 . The gas supply device 3 supplies gas to the gas supply channel 43 of the shower head 4 .

The nozzle 4 includes a liquid supply channel 44 and an air supply channel 43, the liquid supply channel 44 is connected to the liquid supply device 2, the gas supply channel 43 is connected to the gas supply device 3, the gas supply channel 43 is annular, and the gas supply channel 43 is sleeved on the liquid supply On the outside of the channel 44 , the spray head 4 is connected to the AC high voltage generator 1 . In the liquid supply channel 44, the liquid forms a Taylor cone under the joint action of pressure and electrostatic force, and when the electrostatic field increases to a certain strength, the charged part of the liquid overcomes the surface tension and sprays out to form a jet. The end of the outlet section of the liquid supply channel 44 is a tapered tip, and the gas in the gas supply channel 43 converges toward the gas outlet 41 to form an air flow that wraps the liquid outlet 42, thereby realizing jet flow under the shear force of the high-speed air flow and the action of the electric field stretching to obtain nanomaterials.

The receiver 5 includes at least two rod-shaped support arms 53, a rotating shaft 51 and a transmission device 52 for driving the rotating shaft 51 to rotate. One end of the supporting arm 53 is fixedly connected to the rotating shaft 51 and the other end is suspended, and the adjacent supporting arms 53 are arranged at intervals. All the supporting arms 53 form a bowl-shaped rotating surface when the rotating shaft 51 rotates, and the bowl-shaped rotating surface is arranged opposite to the liquid outlet 42 and the air outlet 41 of the spray head 4 . Under the thrust of the high-speed airflow, the fibers accumulate toward the receiver 5, and at the same time, the airflow is guided from the gap of the support arm 53 of the receiver 5, and assists the deposition of nanofibers into a three-dimensional structure. Specifically, the shell of the receiver 5 can be conductive, and both the receiver 5 and the AC high voltage generator 1 are grounded, so as to form a high voltage between the receiver 5 and the shower head 4 .

In this kind of electrospinning device, a high-voltage electric field is formed between the receiver 5 and the nozzle 4 under the action of the AC high-voltage generator 1 to provide an electric field for electrospinning, and the gas outlet 41 of the air supply channel 43 can generate a liquid outlet. The solution in 42 is blown and stretched and forms an airflow between the nozzle 4 and the receiver 5 to assist the stretching of the jet, so that fibers with extremely small diameters can be formed, and the fiber diameter distribution is uniform, the structure is fluffy, and the mechanical properties are superior. At the same time, gaps are provided between adjacent support arms 53, which can effectively allow high-speed airflow to pass through and avoid recoil airflow; in addition, the electrospinning device can prepare a wide range of materials, process stability, and good versatility. Widely used in the field of tissue engineering.

In the above embodiment, the radial section of the liquid supply channel 44 can be circular, the radial section of the gas supply channel 43 can be circular, and the gas supply channel 43 and the liquid supply channel 44 are coaxially arranged and the central axis is a straight line , to improve the uniformity of the fibers, and facilitate the processing of the nozzle 4.

In the above embodiment, one end of the air supply channel 43 in the axial direction is sealed and the other end is the air outlet 41, the middle part of the air supply channel 43 protrudes radially outward on both sides in the axial direction, and the air supply device 3 is connected to At the protruding part, that is, the axial section of the air supply channel 43 is two opposite T-shaped. When the gas supply device 3 supplies gas to the gas supply channel 43, the gas enters the gas supply channel 43 from the protrusion, and flows in the gas supply channel 43 from the protrusion towards the two sides of the axial direction, one side of which is the gas outlet 41, and the gas It flows out directly, and the other side is a seal, and the gas is blocked after flowing to the seal. When the gas continues to flow into the gas supply channel 43, the gap between the protrusion and the seal is filled with gas, which can be used as an air chamber for storing gas to ensure the gas outlet 41 Stability of gas outflow.

In each of the above embodiments, the liquid supply channel 44 sequentially includes an inlet section, a liquid storage section and an outlet section for placing a connecting pipe along the axial direction, and the hole diameter of the inlet section is smaller than the hole diameter of the liquid storage section. Wherein, the aperture of the inlet section is generally consistent with the outer diameter of the pipe connecting the liquid supply passage 44, while the outer diameter of the pipe connected to the liquid supply passage 44 is usually smaller, and the aperture of the liquid storage section is set to be larger than the aperture of the inlet section. A certain amount of liquid is stored between the liquid port 42 and the inlet section to ensure the uniformity and continuity of the liquid storage.

In each of the above-mentioned embodiments, the air supply device 3 may specifically include an air pressure supply device connected to the air supply channel 43 through an air delivery pipe, a precision air pressure regulating valve 45 arranged on the air delivery pipe, a heating device may be provided in the inlet section, and a precision air pressure adjustment valve 45 may be provided on the air delivery pipe. The regulating valve 45 can precisely regulate the gas flux, and the heating device can regulate the temperature of the nozzle 4 to ensure the spinning quality and efficiency.

In each of the above-mentioned embodiments, the liquid supply channel 44 and the gas supply channel 43 can be provided with a temperature measuring device, and the temperature measuring device, the liquid supply device 2, the gas supply device 3 and the heating device are respectively connected with the numerical control device, so that the temperature can be grasped in real time. The temperature conditions in the liquid supply device 2 and the air supply device 3 facilitate the adjustment of the temperature of the environment where the nozzle 4 is located, ensuring spinning efficiency and convenient operation. Specifically, a display device may be provided on the numerical control device to display the temperature measured by the temperature measuring device in real time. Specifically, the temperature measuring device may be a temperature sensor.

In each of the above embodiments, all the support arms 53 can be arranged at equal intervals to further improve the uniformity of the fibers. Of course, the spacing between adjacent support arms 53 can also be set in other ways according to actual needs.

In each of the above-mentioned embodiments, the support arm 53 can be a curved metal sheet or a curved metal rod or a curved plastic rod. Specifically, the support arm 53 can be curved in an arc shape to ensure that the thickness of the fibers everywhere on the support arm 53 is comparatively low. It is uniform and easy to process, which is conducive to reducing costs.

In each of the above-mentioned embodiments, one side of the receiver 5 may be provided with an air guiding device for guiding the direction of gas flow, and the air guiding device and the supporting arm 53 are separately arranged on both sides of the rotating shaft 51 in the axial direction. Specifically, the nozzle 4, the receiver 5, and the gas guide device can be arranged in sequence from top to bottom, and the gas guide device can draw the gas downward from the support arm 53 to guide the gas flow direction.

Each embodiment in this specification is described in a progressive manner, each embodiment focuses on the difference from other embodiments, and the same and similar parts of each embodiment can be referred to each other.

The electrospinning device provided by the present invention has been introduced in detail above. In this paper, specific examples are used to illustrate the principle and implementation of the present invention, and the descriptions of the above embodiments are only used to help understand the method and core idea of the present invention. It should be pointed out that for those skilled in the art, without departing from the principles of the present invention, some improvements and modifications can be made to the present invention, and these improvements and modifications also fall within the protection scope of the claims of the present invention.

Claims (9)

1. a kind of electrostatic spinning apparatus, it is characterised in that including：

Ac high voltage generator (1)；

Liquid feed device (2), including micro-injection pump；

Feeder (3)；

Shower nozzle (4), the shower nozzle (4) is including connecting the liquid feeding channel (44) of the liquid feed device (2) and connecting the supply dress The air supply channel (43) of the ring-type of (3) is put, the air supply channel (43) is sheathed on the outside of the liquid feeding channel (44), the confession The outlet section end of liquid passage (44) is cone point, and the shower nozzle (4) connects the ac high voltage generator (1)；

Receiver (5), including at least two shaft-like support arms (53), rotating shaft (51) and for drive the rotating shaft (51) rotate Transmission device (52), one end of the support arm (53) is fixedly connected the rotating shaft (51) and the other end is hanging, adjacent described Support arm (53) interval setting, all support arms (53) form the bowl-shape surface of revolution when the rotating shaft (51) is rotated, described The bowl-shape surface of revolution is oppositely arranged with the liquid outlet (42) of the shower nozzle (4) and gas outlet (41).

2. electrostatic spinning apparatus according to claim 1, it is characterised in that the radial section of the liquid feeding channel (44) is Circle, the radial section of the air supply channel (43) is annular, and the air supply channel (43) and the liquid feeding channel (44) It is coaxially disposed, and central shaft is straight line.

3. electrostatic spinning apparatus according to claim 2, it is characterised in that in the axial direction of the air supply channel (43) End closure and the other end are the gas outlet (41), and the air supply channel (43) middle part in the axial direction is projected radially outward in two Side, and the feeder (3) is connected at protrusion.

4. electrostatic spinning apparatus according to claim 3, it is characterised in that the liquid feeding channel (44) is wrapped successively vertically Inducer, liquid storage section and the outlet section for placing connecting tube are included, the aperture of the inducer is less than liquid storage section Aperture.

5. electrostatic spinning apparatus according to claim 4, it is characterised in that the feeder (3) is including by gas transmission The air pressure feeding mechanism that pipe is connected with the air supply channel (43), the accurate air pressure regulator (45) on the appendix, Heater is provided with the inducer.

6. electrostatic spinning apparatus according to claim 5, it is characterised in that the liquid feeding channel (44) and the supply are logical Temperature measuring equipment, the temperature measuring equipment, the liquid feed device (2), the feeder (3) and the heating are equipped with road (43) Device is connected with numerical control device respectively.

7. electrostatic spinning apparatus according to claim 1 to 6 any one, it is characterised in that all support arms (53) spaced set.

8. electrostatic spinning apparatus according to claim 7, it is characterised in that the support arm (53) is the sheet metal of bending Or the metallic rod or the plastic bar of bending of bending.

9. electrostatic spinning apparatus according to claim 7, it is characterised in that the side of the receiver (5) be provided with for The gas operated device of gas flow, the gas operated device is guided to be divided into the axial direction of the rotating shaft (51) with the support arm (53) Both sides.