CN106901868A - A kind of upper joint capsule rebuilds reparation sticking patch and preparation method thereof - Google Patents
A kind of upper joint capsule rebuilds reparation sticking patch and preparation method thereof Download PDFInfo
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- CN106901868A CN106901868A CN201710101636.9A CN201710101636A CN106901868A CN 106901868 A CN106901868 A CN 106901868A CN 201710101636 A CN201710101636 A CN 201710101636A CN 106901868 A CN106901868 A CN 106901868A
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- layer
- sticking patch
- biological tissue
- fibrage
- upper joint
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0063—Implantable repair or support meshes, e.g. hernia meshes
Abstract
The present invention discloses a kind of upper joint capsule and rebuilds reparation sticking patch, including two-layer biological tissue layer and one layer of fibrage, biological tissue's layer is identical with fibrage geomery, the two-layer biological tissue layer is formed by a piece of biomembrane doubling, the fibrage is clipped between two-layer biological tissue layer, and sticking patch forms the sandwich composite construction of biological tissue's layer/fibrage.The present invention can be able to ensure that sticking patch has enough mechanical property and biocompatibilities as the sticking patch that the operation of upper joint capsule is rebuild under arthroscope, the sandwich composite construction of its biological tissue's layer/fibrage.Invention also discloses the preparation method of the sticking patch, and the method is simple to operate, meets operation use requirement.
Description
Technical field
The present invention relates to medical patch field, and in particular to a kind of upper joint capsule rebuilds reparation sticking patch and its preparation side
Method.
Background technology
Rotator cuff tear is common Shoulder joint, and the incidence of disease increases with advancing age and gradually.Rotator cuff tear is
Cause shoulder arthralgia, mobility reduction, the common cause of miopragia, account for the 60% of shoulder lesion.Chronic regression type is huge
Big unrepairable rotator cuff tear is difficult to the problems such as muscular atrophy and fatty infiltration usually because tendon tissue regression is followed the string
Repair completely.To through the invalid Patients with Rotator Cuff Injury After of expectant treatment and shoulder sleeve mass lesions patient, surgical operation being usually taken
Treatment repairing tear tendon, so as to mitigate pain, and rebuilds function of joint.Conventional solution be usually Sub acromial decompression into
Type and cleaning, partial repair, tendon of subscapularis muscle indexing, great circle Muscle transplant, supraspinatus tendon lifting art, triangle musculocutaneous flap are rebuild, the back of the body
Platysma indexing, pectoralis major indexing, tear portion tendon grafting, or anti-shoulder displacement technique.But these methods are in clinical effectiveness
Display has more or less otherness, and all there are various postoperative complications, may be with infection, failure, fracture, nerve
The multiple risks such as vascular complication.
The maximum of the huge rotator cuff tear of unrepairable refers to that disease is exactly the pain that subacromial impingement is caused, the muscle of shoulder joint
Powerless, hand arm held upward is limited.It is causing these main reason is that the missing of Glenohumeral joint top stability, shoulder sleeve muscle (hilllock
Upper flesh) function lose.It is a kind of relatively new surgical technic that upper joint capsule is rebuild under arthroscope, and technique is by implantation
Graft connects Scapula glenoid and major tubercle recovers the effect that upper joint capsule structure pushes the head of humerus to reach, and can recover shoulder joint
Top stability.Technique can be completed under mirror, and compared to anti-shoulder displacement technique, whole process risk is very small.And tendon
The weak spot in shoulder sleeve repair process, pulled in art and attempted by the shoulder tissue sleeve that bulk tears be fixed on before injury it is former attached
A little more difficult, head of humerus covering not enough problem when now needing to strengthen sticking patch solution huge rotator cuff tear with shoulder sleeve structure,
Ensure the mechanical property of neoplasty back porch tissue sleeve, maintain the stability and function of shoulder joint.Rebuild currently used under arthroscope
The patching material of upper joint capsule uses autologous fascia late, with good biological attribute, will not cause the inflammatory reaction of body.But
The fascia late thickness of each patient is different, and the sticking patch mechanical property being made has larger difference, and fascia late sticking patch can be slowly
There is creep stretching, it is thinning elongated, the strength of the head of humerus is pushed so as to reduce, make to have pushed the head of humerus of reset, may
Occur the head of humerus upper shifting, the phenomenon of the loss that resets on a small quantity after surgery.
In view of drawbacks described above, creator of the present invention obtains in one kind of the invention finally by prolonged research and practice
Capsular ligament rebuilds reparation sticking patch and preparation method thereof.
The content of the invention
To solve above-mentioned technological deficiency, the technical solution adopted by the present invention is, there is provided a kind of upper joint capsule is rebuild and repaired
With sticking patch, including two-layer biological tissue layer and one layer of fibrage, biological tissue's layer is identical with fibrage geomery, described
Two-layer biological tissue layer is formed by a piece of biomembrane doubling, and the fibrage is clipped between two-layer biological tissue layer, and sticking patch is formed
The sandwich composite construction of biological tissue's layer/fibrage.
Preferably, the biomembrane is autologous fascia late.
Preferably, the fibrage is formed by polyester fiber braiding.
Preferably, the polyester fiber is pet fiber, PTT Fiber
Or poly fiber.
Preferably, the fibrage has loose structure, its pore size is 250-350um.
Preferably, the sticking patch is rectangular, biological tissue's layer and fibrage are stitched together by fixed suture,
Four sides of the sticking patch have a stitch points per 0.5cm, have in the middle part of the sticking patch and at least connect two stitch points.
Preferably, four sides of the sticking patch have compensation section, connected for performing the operation, compensation distance in side both sides long is 1-
1.5cm, broadside both sides compensation distance is 0.5-1cm.
Preferably, biological tissue's layer and the fiber layer thickness relation meet formula：
Wherein, X is biological tissue's thickness degree, and Y is the fiber layer thickness, and thickness unit is mm.
A kind of upper joint capsule rebuilds the preparation method of reparation sticking patch, it is characterised in that comprise the following steps successively：
Stp1：Measurement tearing port size, according to the tearing port Size calculation sticking patch length and width size；
Stp2：Determine autologous fascia late size by the patch size, autologous fascia late is removed by size requirement, by its table
Face is scabbled, and four sides repair rectangular, measure autologous fascia late thickness；
Stp3：Polyester fiber piece is cut out by size requirement, the polyester fiber piece thickness is thick according to the autologous fascia late
Degree is calculated；
Stp4：The autologous fascia late is folded to form upper and lower two-layer biological tissue layer, the polyester fiber piece is clipped in
As fibrage in the middle of two-layer biological tissue layer；
Stp5：Four side seams of sticking patch are closed, there are a stitch points per 0.5cm, middle part has at least two stitch points.
Preferably, the patch size is length is more than tearing port 2-3cm, width is more than tearing port 1-2cm, and thickness is more than
Equal to 1cm；The autologous fascia late length is the twice of the sticking patch length, and width is identical with the patch width；It is described poly-
Ester fiber piece length and width is identical with the sticking patch.
Compared with the prior art the beneficial effects of the present invention are：
1, the sticking patch that the present invention can perform the operation as reconstruction upper joint capsule under arthroscope, its biological tissue's layer/fibrage
Sandwich composite construction is able to ensure that sticking patch has enough mechanical property and biocompatibilities.
2, there is the fibrage in the middle of sticking patch sufficient intensity to maintain shoulder joint reset, and support effect can be played again, prevent from mending
Piece creep, upper and lower both sides biological tissue layer cell proliferation and Osteoblast Differentiation have facilitation, and histocyte can be fine along polyester
Dimension growth, finally grows up to one layer of upper joint lens capsule tissue of fully integratedization, recovers the function that muscular strength maintains shoulder joint.Fibrage is more
Pore structure can disturb the formation hyperplasia of non-tendon or ligament in tissue, reduce the formation of internal cicatricial tissue.
3, the preparation that upper joint capsule rebuilds reparation sticking patch determines patch size according to tearing port, meets individual patients need
Ask, biological tissue's layer/fibrage multiple spot suture can prevent the relative slip of interlayer from departing from.
4, by controlling the thickness of biological tissue's layer/fibrage, make sticking patch that there is certain intensity and pliability, it is ensured that to mend
The uniformity of piece mechanical property, maintains the stability and function of shoulder joint.
Brief description of the drawings
In order to illustrate more clearly of the technical scheme in various embodiments of the present invention, below will be to being wanted needed for embodiment description
The accompanying drawing for using is briefly described.
Fig. 1 is the profile that upper joint capsule of the invention rebuilds reparation sticking patch；
Fig. 2 is the front view that upper joint capsule of the invention rebuilds reparation sticking patch；
Fig. 3 is the structure chart of fibrage of the present invention；
Fig. 4 is the flow chart that upper joint capsule of the present invention rebuilds reparation sticking patch preparation method；
Fig. 5 is the datagram of autologous fascia late in experimental example of the present invention；
Fig. 6 is the datagram of sticking patch in experimental example of the present invention.
Specific embodiment
Below in conjunction with accompanying drawing, the technical characteristic above-mentioned and other to the present invention and advantage are described in more detail.
Embodiment 1
As shown in figure 1, a kind of upper joint capsule rebuilds reparation sticking patch, including two-layer biological tissue layer 1 and one layer of fibrage
2, two-layer biological tissue layer 1 is formed by a piece of biomembrane doubling, and the fibrage 2 is clipped between two-layer biological tissue layer 1, described
Biological tissue's layer 1 is identical with the geomery of fibrage 2, and sticking patch forms the sandwich composite construction of biological tissue's layer/fibrage.
With reference to shown in Fig. 2, the sticking patch is rectangular, and its biological tissue layer 1 and fibrage 2 pass through fixed suture 3 by four
Side seam is combined, per 0.5cm have a stitch points, it is ensured that interlayer without departing from, and sticking patch middle part have two stitch points,
Prevent relative slip.Patch size is more than tearing port, and compensation section is left on four sides, for fixation of performing the operation.
The present invention can provide enough power as the sticking patch that the operation of upper joint capsule is rebuild under arthroscope, its fibrage
Learn performance, prevent sticking patch creep from stretching, it is thinning elongated, so as to avoid it is postoperative occur the head of humerus it is upper on a small quantity move, reset showing of losing
As biological tissue's layer can provide biocompatibility, promotion organization cell growth, such biological tissue's layer/fibrage sandwich
Composite construction makes sticking patch while being provided with good biocompatibility and mechanical property.
Embodiment 2
A kind of upper joint capsule rebuilds reparation sticking patch, including two-layer biological tissue 1 one layers of fibrage 2 of layer, two-layer biology group
Tissue layer 1 is formed by a piece of biomembrane doubling, and fibrage 2 is clipped between two-layer biological tissue layer 1, the biological tissue 1 and fiber
2 geomery of layer are identical, are stitched together by fixed suture 3, and the sandwich that sticking patch forms biological tissue's layer/fibrage is answered
Close structure.The biomembrane is autologous fascia late, and autogenous cell can be promoted to grow.The fibrage 2 is by poly terephthalic acid
Glycol ester fibrage is formed, and the material has good mechanical performance and biocompatibility.
With reference to shown in Fig. 3, the fibrage 2 has loose structure, and its pore size is 250um, and loose structure can be done
The formation hyperplasia of non-tendon or ligament in tissue is disturbed, the formation of internal cicatricial tissue is reduced, it is ensured that joint lens capsule tissue is normal
Growth.
The sticking patch is rectangular, and its four side has a compensation section, and compensation distance in side both sides long is 1cm, the compensation of broadside both sides away from
From being 0.5cm.Described reparation is closed with the side seam of sticking patch four, has a stitch points per 0.5cm, and middle part has two stitch points.Institute
Sticking patch thickness is stated more than or equal to 10cm, it is ensured that sticking patch has good mechanical property.
Woven sticking patch is sent into shoulder joint chamber by syringe during upper joint capsule reconstruction operations, by sticking patch medial extremity with
Mattress suture is fixed on Scapula glenoid upper limb, and sticking patch rear side end carries out side side seam conjunction with infraspinous muscle, and outboard end is quick with pre-knotted
Suture bridge technology is fixed on greater tubercles of humerus, completes sticking patch and fixes.Fibrage 2 in the middle of postoperative sticking patch plays support effect, tool
There is sufficient intensity to maintain shoulder joint reset, prevent sticking patch creep, upper and lower both sides biological tissue 1 cell proliferation of layer and Osteoblast Differentiation
There is facilitation, histocyte can grow along fibrage 2, finally grow up to one layer of upper joint lens capsule tissue of fully integratedization, it is extensive
Multiple muscular strength maintains the function of shoulder joint.
Embodiment 3
A kind of upper joint capsule rebuilds reparation sticking patch, including two-layer biological tissue layer and one layer of fibrage, two-layer biology group
Tissue layer is formed by a piece of autologous fascia late doubling, and fibrage is clipped between two-layer biological tissue layer, the biological tissue and fiber
Layer geomery is identical, is stitched together by fixed suture, and the sandwich that sticking patch forms biological tissue's layer/fibrage is combined
Structure.The sticking patch is rectangular, and its four side has compensation section, and compensation distance in side both sides long is 1.5cm, broadside both sides compensation distance
It is 1cm.Described reparation is closed with the side seam of sticking patch four, has a stitch points per 0.5cm, and middle part has four stitch points.The fibre
Dimension layer is formed by PTT Fiber braiding, and with loose structure, its pore size is 350um.
Biological tissue's layer and fiber layer thickness relation meets formula：
Wherein, X is biological tissue's thickness degree, and Y is the fiber layer thickness, and thickness unit is mm.By controlling to give birth to
The thickness of thing organized layer/fibrage, it is ensured that the uniformity of sticking patch mechanical property, maintains the stability and function of shoulder joint.
Embodiment 4
A kind of upper joint capsule rebuilds reparation sticking patch, including two-layer biological tissue layer and one layer of fibrage, two-layer biology group
Tissue layer is formed by a piece of autologous fascia late doubling, and fibrage is clipped between two-layer biological tissue layer, the biological tissue and fiber
Layer geomery is identical, is stitched together by fixed suture, and the sandwich that sticking patch forms biological tissue's layer/fibrage is combined
Structure.The sticking patch is rectangular, and its four side has compensation section, and compensation distance in side both sides long is 1.2cm, broadside both sides compensation distance
It is 0.8cm.Described reparation is closed with the side seam of sticking patch four, has a stitch points per 0.5cm, and middle part has three stitch points.It is described
Fibrage is formed by poly fiber's braiding, and with loose structure, its pore size is 300um.The life
The thickness of thing organized layer is 4mm, and the thickness of the fibrage is 2mm.
Embodiment 5
As shown in figure 4, a kind of upper joint capsule rebuilds reparation sticking patch preparation method, comprise the following steps：
Stp1：Patch size confirmation, measures tearing port size, according to the tearing port Size calculation sticking patch length and width size,
Patch size is that length is more than tearing port 2-3cm, and width is more than tearing port 1-2cm；
Stp2：Fascia late takes out processing, and autologous fascia late size is determined by the patch size, and the autologous fascia late is long
It is the twice of sticking patch length to spend, and width is identical with patch width, and autologous fascia late is removed by size requirement, and its surface is scabbled,
Four sides repair rectangular, measure autologous fascia late thickness；
Stp3：Polyester fiber piece is carried out by size requirement to cut out, the polyester fiber piece length and width is identical with the sticking patch,
Polyester fiber piece thickness is confirmed according to autologous fascia late thickness；
Stp4：Sandwich structure is stacked, and the autologous fascia late is folded to form into upper and lower two-layer biological tissue layer, will be described
Polyester fiber piece is clipped in the middle of two-layer as fibrage；
Stp5：Sticking patch suture is fixed, and four side seams of sticking patch are closed, and has a stitch points per 0.5cm, and middle part has at least
Connect two stitch points.
This sandwich composite construction sticking patch preparation method is simple, meets operation use requirement, and the size of sticking patch is according to tearing
Breach determines that be adapted to individual needs of patients, biological tissue's layer/fibrage multiple spot suture can prevent the relative slip of interlayer from taking off
From.
Embodiment 6
This implementation part unlike the embodiments above is that biological tissue's layer and fiber layer thickness relation meets formula：
Wherein, X is biological tissue's thickness degree, and Y is the fiber layer thickness, and thickness unit is mm.Polyester in Stp3
Fibre plate thickness can be calculated according to autologous fascia late thickness and formula, by the thickness for controlling biological tissue's layer/fibrage
Degree, it is ensured that the uniformity of sticking patch mechanical property.
Experimental example
The autologous fascia late and sticking patch of same thickness are done into tension test respectively, its mechanical property is determined.
As shown in Figure 5, Figure 6, it is respectively autologous fascia late and sticking patch power-time, force-displacement relationship figure.
Wherein L1 is the force-time curve of autologous fascia late, and L2 is the force-displacement curve of autologous fascia late, and L3 is sticking patch
Force-time curve, L4 for sticking patch force-displacement curve.
Following table is the parameter measured from Fig. 5, Fig. 6：
| Extrusion | Maximum weighted (kN) | Deformational displacement (mm) can be recovered | Deformation time (s) can be recovered |
| Fascia late | 0.87 | 7.4 | 88 |
| Sticking patch | 3.59 | 19.2 | 208 |
The maximum weighted of the maximum weighted less than sticking patch of autologous fascia late is understood by chart；The sticking patch in the case of identical power
Displacement be less than autologous fascia late, and sticking patch maximum displacement more than autologous fascia late, i.e. sticking patch tensile strength and can
Retractility is superior to autologous fascia late.
Presently preferred embodiments of the present invention is the foregoing is only, is merely illustrative for the purpose of the present invention, and it is non-limiting
's.Those skilled in the art understanding, many changes can be carried out in the spirit and scope that the claims in the present invention are limited to it,
Modification, in addition it is equivalent, but fall within protection scope of the present invention.
Claims (10)
1. a kind of upper joint capsule rebuilds reparation sticking patch, it is characterised in that including two-layer biological tissue layer and one layer of fibrage, institute
State biological tissue's layer identical with fibrage geomery, the two-layer biological tissue layer is formed by a piece of biomembrane doubling, described
Fibrage is clipped between two-layer biological tissue layer, and sticking patch forms the sandwich composite construction of biological tissue's layer/fibrage.
2. upper joint capsule as claimed in claim 1 rebuilds reparation sticking patch, it is characterised in that the biomembrane is autologous wealthy muscle
Film.
3. upper joint capsule as claimed in claim 1 rebuilds reparation sticking patch, it is characterised in that the fibrage is by polyester fiber
Braiding is formed.
4. upper joint capsule as claimed in claim 3 rebuilds reparation sticking patch, it is characterised in that the polyester fiber is poly- to benzene
Naphthalate fiber, PTT Fiber or poly fiber.
5. upper joint capsule as claimed in claim 4 rebuilds reparation sticking patch, it is characterised in that the fibrage has porous knot
Structure, its pore size is 250-350um.
6. upper joint capsule as described in claim 1-5 is any rebuilds reparation sticking patch, it is characterised in that the sticking patch is into square
Shape, biological tissue's layer and fibrage are stitched together by fixed suture, and four sides of the sticking patch have one per 0.5cm
Individual stitch points, have in the middle part of the sticking patch and at least connect two stitch points.
7. upper joint capsule as claimed in claim 6 rebuilds reparation sticking patch, it is characterised in that four sides of the sticking patch have mends
Portion is repaid, is connected for performing the operation, compensation distance in side both sides long is 1-1.5cm, and broadside both sides compensation distance is 0.5-1cm.
8. upper joint capsule as claimed in claim 1 rebuilds reparation sticking patch, it is characterised in that biological tissue's layer and described
Fiber layer thickness relation meets formula：
Wherein, X is biological tissue's thickness degree, and Y is the fiber layer thickness, and thickness unit is mm.
9. a kind of upper joint capsule rebuilds the preparation method of reparation sticking patch, it is characterised in that comprise the following steps successively：
Stp1：Measurement tearing port size, according to the tearing port Size calculation sticking patch length and width size；
Stp2：Determine autologous fascia late size by the patch size, autologous fascia late is removed by size requirement, its surface is cut
Flat, four sides repair rectangular, measure autologous fascia late thickness；
Stp3：Polyester fiber piece is cut out by size requirement, the polyester fiber piece thickness is according to the autologous fascia late thickness gauge
Obtain；
Stp4：The autologous fascia late is folded to form upper and lower two-layer biological tissue layer, the polyester fiber piece is clipped in two-layer
As fibrage in the middle of biological tissue's layer；
Stp5：Four side seams of sticking patch are closed, there are a stitch points per 0.5cm, middle part has at least two stitch points.
10. upper joint capsule as claimed in claim 9 rebuilds the preparation method of reparation sticking patch, it is characterised in that the sticking patch
Length be more than tearing port 2-3cm, width be more than tearing port 1-2cm, thickness be more than or equal to 1cm；The autologous fascia late length
It is the twice of the sticking patch length, width is identical with the patch width；The polyester fiber piece length and width and the sticking patch phase
Together.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710101636.9A CN106901868B (en) | 2017-02-24 | 2017-02-24 | A kind of upper joint capsule rebuilds reparation sticking patch and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710101636.9A CN106901868B (en) | 2017-02-24 | 2017-02-24 | A kind of upper joint capsule rebuilds reparation sticking patch and preparation method thereof |
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| Publication Number | Publication Date |
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| CN106901868A true CN106901868A (en) | 2017-06-30 |
| CN106901868B CN106901868B (en) | 2018-08-14 |
Family
ID=59208776
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| CN201710101636.9A Expired - Fee Related CN106901868B (en) | 2017-02-24 | 2017-02-24 | A kind of upper joint capsule rebuilds reparation sticking patch and preparation method thereof |
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| CN107837129A (en) * | 2017-12-16 | 2018-03-27 | 诺迈尔（苏州）医学科技有限公司 | Non-degradable class hernia paster biocompatibility improved method |
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| CN107837129A (en) * | 2017-12-16 | 2018-03-27 | 诺迈尔（苏州）医学科技有限公司 | Non-degradable class hernia paster biocompatibility improved method |
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| CN106901868B (en) | 2018-08-14 |
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