CN106896062B - 生物样品用的光学测量装置中的校准和/或检错 - Google Patents

生物样品用的光学测量装置中的校准和/或检错 Download PDF

Info

Publication number
CN106896062B
CN106896062B CN201611157483.1A CN201611157483A CN106896062B CN 106896062 B CN106896062 B CN 106896062B CN 201611157483 A CN201611157483 A CN 201611157483A CN 106896062 B CN106896062 B CN 106896062B
Authority
CN
China
Prior art keywords
measurement
measurement channel
reference factor
detection signal
channel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201611157483.1A
Other languages
English (en)
Chinese (zh)
Other versions
CN106896062A (zh
Inventor
R·哈贝尔斯
M·托曼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of CN106896062A publication Critical patent/CN106896062A/zh
Application granted granted Critical
Publication of CN106896062B publication Critical patent/CN106896062B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00594—Quality control, including calibration or testing of components of the analyser
    • G01N35/00693—Calibration
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/251—Colorimeters; Construction thereof
    • G01N21/253—Colorimeters; Construction thereof for batch operation, i.e. multisample apparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/274—Calibration, base line adjustment, drift correction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/4738—Diffuse reflection, e.g. also for testing fluids, fibrous materials
    • G01N21/474—Details of optical heads therefor, e.g. using optical fibres
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/026—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having blocks or racks of reaction cells or cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/12—Circuits of general importance; Signal processing
    • G01N2201/127—Calibration; base line adjustment; drift compensation

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Engineering & Computer Science (AREA)
  • Theoretical Computer Science (AREA)
  • Mathematical Physics (AREA)
  • Quality & Reliability (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
CN201611157483.1A 2015-12-17 2016-12-15 生物样品用的光学测量装置中的校准和/或检错 Active CN106896062B (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15200769.6A EP3182096B1 (en) 2015-12-17 2015-12-17 Calibration and/or error detection in an optical measurement device for biological samples
EP15200769.6 2015-12-17

Publications (2)

Publication Number Publication Date
CN106896062A CN106896062A (zh) 2017-06-27
CN106896062B true CN106896062B (zh) 2020-11-06

Family

ID=54979437

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201611157483.1A Active CN106896062B (zh) 2015-12-17 2016-12-15 生物样品用的光学测量装置中的校准和/或检错

Country Status (5)

Country Link
US (1) US11353471B2 (https=)
EP (1) EP3182096B1 (https=)
JP (1) JP6799454B2 (https=)
CN (1) CN106896062B (https=)
ES (1) ES2778677T3 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES3038129T3 (en) * 2015-06-26 2025-10-09 Abbott Lab Rotating device in a diagnostic analyzer
EP3882636B1 (en) * 2016-07-21 2025-10-01 Siemens Healthcare Diagnostics Inc. Eliminating source lamp intensity drift effect using reference measurement between cuvettes
EP3290905B1 (en) * 2016-09-05 2022-10-19 F. Hoffmann-La Roche AG Signal offset determination and correction
WO2019044969A1 (ja) * 2017-09-01 2019-03-07 ウシオ電機株式会社 マイクロプレートリーダー
EP3746755B1 (en) * 2018-01-30 2022-09-28 GrainSense Oy A method for calibrating an integrating cavity
CN112004604B (zh) * 2018-04-23 2023-02-03 迈恩医疗解决方案有限公司 用于获得流体介质的测量信号的光学测量单元和光学测量方法
EP3784401A1 (de) * 2018-04-23 2021-03-03 Meon Medical Solutions GmbH & Co. KG Automatischer analysator und optisches messverfahren zur gewinnung von messsignalen von flüssigen medien
EP3614128B1 (en) * 2018-08-22 2023-04-26 F. Hoffmann-La Roche AG A method to correct signal light intensities measured by a detector of a detection unit in a laboratory instrument
CA3126148A1 (en) * 2019-01-10 2020-07-16 Travera LLC Calibration of a functional biomarker instrument
EP3912007A4 (en) 2019-01-10 2022-11-02 Travera LLC IDENTIFICATION OF CANCER THERAPIES
JP7276462B2 (ja) * 2019-08-06 2023-05-18 株式会社島津製作所 生化学分析装置及び生化学分析方法
KR102522278B1 (ko) * 2021-10-29 2023-04-17 주식회사 신코 듀얼 어레이 센서를 이용한 고속 흡광도 측정 마이크로플레이트 리더기
CN120457328A (zh) * 2023-01-10 2025-08-08 索尼集团公司 生物样品分析器、生物样品分析系统及用于验证生物样品分析器的状态的方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4591550A (en) 1984-03-01 1986-05-27 Molecular Devices Corporation Device having photoresponsive electrode for determining analytes including ligands and antibodies
JPS62115348A (ja) * 1985-09-30 1987-05-27 モレキユラ−　デバイスイズ　コ−ポレイシヨン 多ビ−ムによる光度測定装置および測定方法
US7217574B2 (en) * 2000-10-30 2007-05-15 Sru Biosystems, Inc. Method and apparatus for biosensor spectral shift detection
JP3838501B2 (ja) * 2001-12-05 2006-10-25 Ｋｄｄｉ株式会社 光バースト信号ルーチング方式
EP1394532A3 (en) * 2002-08-28 2004-06-09 Fuji Photo Film Co., Ltd. Measuring apparatus
JP4483333B2 (ja) * 2004-02-17 2010-06-16 株式会社島津製作所 光測定装置における測定方法及びチャンネル間偏差測定用標準器
US7339668B2 (en) 2005-10-18 2008-03-04 Thermo Electron Scientific Instruments Llc Spectrometer for analysis of multiple samples
CN200950139Y (zh) 2006-07-19 2007-09-19 北京工业大学 用于生物pcr微通道荧光检测的标准芯片
US7674616B2 (en) * 2006-09-14 2010-03-09 Hemosense, Inc. Device and method for measuring properties of a sample
JP2009053029A (ja) 2007-08-27 2009-03-12 Olympus Corp 自動分析装置
US20110001963A1 (en) * 2009-07-02 2011-01-06 Durack Gary P System and method for the measurement of multiple emissions from multiple parallel flow channels in a flow cytometry system
US9091637B2 (en) 2009-12-04 2015-07-28 Duke University Smart fiber optic sensors systems and methods for quantitative optical spectroscopy
WO2012054028A1 (en) * 2010-10-20 2012-04-26 Analogic Corporation Method of calibrating and correcting color-bleed factors for color separation in dna analysis
WO2013134491A1 (en) 2012-03-09 2013-09-12 Siemens Healthcare Diagnostics Inc. Calibration method for reagent card analyzers
GB2506375B (en) * 2012-09-27 2017-10-18 Epistem Ltd Data processing and analysis systems
CN103528952B (zh) 2013-10-25 2016-07-06 中国科学院合肥物质科学研究院 一种开放光路式气体分析仪通量校正测量装置及测量方法
MX361975B (es) * 2013-12-19 2018-12-19 Halliburton Energy Services Inc Estandarización de sensores cruzados.
CN104198382A (zh) 2014-06-18 2014-12-10 上海理工大学 基于检测农药残留的双通道检测装置及方法

Also Published As

Publication number Publication date
CN106896062A (zh) 2017-06-27
EP3182096A1 (en) 2017-06-21
JP6799454B2 (ja) 2020-12-16
ES2778677T3 (es) 2020-08-11
US20170176478A1 (en) 2017-06-22
JP2017111145A (ja) 2017-06-22
EP3182096B1 (en) 2020-01-15
US11353471B2 (en) 2022-06-07

Similar Documents

Publication Publication Date Title
CN106896062B (zh) 生物样品用的光学测量装置中的校准和/或检错
EP3086123B1 (en) Automatic analysis device
EP1887356B1 (en) Automatic analyzer
US10684298B2 (en) Automated analyzer
EP1965214A2 (en) Automatic analyzer
US9310388B2 (en) Automatic analyzer and analysis method
US11486886B2 (en) Automatic analyzer and automatic analysis method
CN114550826A (zh) 一种实时荧光定量pcr的数据分析系统及其方法
WO2020121726A1 (ja) 自動分析装置
US20220003685A1 (en) Analyzer and analysis method
US9746485B2 (en) Automatic blood coagulation analysis device
CN107796760B (zh) 信号漂移确定与校正
US20080206100A1 (en) Automatic analyzer
US20240003923A1 (en) Calibration and validation of cuvettes in automated chemical analyzers

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant