CN106880647B - Baijiang Dan and its preparation method - Google Patents

Baijiang Dan and its preparation method Download PDF

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CN106880647B
CN106880647B CN201710184170.3A CN201710184170A CN106880647B CN 106880647 B CN106880647 B CN 106880647B CN 201710184170 A CN201710184170 A CN 201710184170A CN 106880647 B CN106880647 B CN 106880647B
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率秀冰
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Lv Xiubing
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K33/00Medicinal preparations containing inorganic active ingredients
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions

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Abstract

The invention relates to a white blood-reducing pill which is prepared from mercury, alum, potassium nitrate, salt, melanterite, cinnabar, borax, realgar, pearl powder and official powder. The invention also provides a preparation method of the white Jiangtangdan. The leukopenia pill provided by the invention is prepared from raw materials including mercury, alum, potassium nitrate, salt, melanterite, cinnabar, borax, realgar, pearl powder and official powder, is used for treating carbuncle-abscess, back-on furunculosis, dorsal furunculosis diffusion, sore head collapse, necrosis difficult to fall off, ulceration in sores for a long time without perforation, has a remarkable effect in treating the diseases by traditional Chinese medicine, is short in course of disease, difficult to relapse and obvious in advantage, adopts less medicinal flavors, and ensures that the effects of various medicinal materials in the aspect of scabies are mutually enhanced through reasonable compatibility, so that an obvious synergistic effect is shown.

Description

Baijiang Dan and its preparation method
Technical Field
The invention relates to a medicament for treating carbuncle, cellulitis, back furunculosis, dorsal furuncle diffusion, sore head flattening and collapse, necrosis difficult to fall off, ulceration in sores for a long time and no perforation, in particular to a Baijiang Dan and a preparation method thereof.
Background
Peripheral vascular diseases and lymphangioleiomyomatosis are diseases frequently seen in life of people, including thrombotic obliterative angiitis, arteriosclerotic obliteration, diabetic foot and the like in western medicine, and in the treatment of the diseases in western medicine, anti-inflammation and pain-relieving agents, vasodilators and other symptomatic treatments are generally selected, so that the effect is slow and the diseases are easy to relapse.
Disclosure of Invention
The technical problem to be solved by the invention is as follows: the Chinese medicine has obvious effect, short course of disease, difficult recurrence and obvious advantages in treating the diseases, and has important significance in treating by developing external Chinese medicine to shorten the treatment course.
The white blood-reducing pill is prepared from the following raw material medicines: hydrargyrum, Alumen, Sal Nitri, Sal, Melanteritum, Cinnabaris, Borax, Realgar, Margarita powder, and hydrocerussitum.
Preferably, the traditional Chinese medicine is prepared from the following raw material medicines: 25-30g of mercury, 20-25g of alum, 18-20g of potassium nitrate, 8-10g of table salt, 8-10g of melanterite, 15-20g of cinnabar, 8-10g of borax, 3-5g of realgar, 15-20g of pearl powder and 15-20g of official powder.
Preferably, the traditional Chinese medicine is prepared from the following raw material medicines: 30g of mercury, 24g of alum, 20g of potassium nitrate, 10g of salt, 10g of melanterite, 20g of cinnabar, 10g of borax, 5g of realgar, 20g of pearl powder and 20g of official powder.
The invention also provides a preparation method of the white Jiangtangdan, which comprises the following steps:
1) testing the pot: the primary and secondary tanks are checked once, and water is added for testing if necessary, and the base tire can be carried out if no leakage hole exists and the opening is not tight;
2) a tire is seated: the method comprises grinding Alumen, Sal Nitri, Melanteritum, Cinnabaris, Borax, Realgar, Margarita powder, and hydrocerussitum respectively, adding hydrargyrum, grinding to a degree of no star, making into medicinal blank, dividing the medicinal blank into three parts, placing the medicinal blank in the side of the bottom of the sub-tank, tilting the tank to 45 deg.C, placing the tank at the fire side of the fire, baking until the medicinal blank melts, turning over, placing the sub-tank into one part of the medicinal blank after rotating the sub-tank at 120 deg.C until the medicinal blank solidifies in the sub-tank, rotating the tank at 120 deg.C, placing the last part of the medicinal blank, standing the sub-tank until the medicinal blank solidifies completely in the tank, covering the main tank on the sub-tank, opening the main tank, checking, and if there is no water gas in the main tank, making a tire, then placing the tire at the side of the fire, opening the main tank until no water gas is in order to be baked, if yellow smoke emerges from the pot, the mercury is removed, and the efficacy of the refined smoke is greatly reduced and poisoned;
3) and (3) can sealing: tightly closing two openings of the primary and secondary tanks, regulating the shape of mud with water by using prepared calcined gypsum powder and salt powder, fixing the primary and secondary tanks by one hand, plugging the mud into the joint of the primary and secondary tanks by the other hand, compacting and sealing, smearing water by hands to smooth the joint, drying in the sun or drying beside a stove, checking whether a crack exists, folding the crack into a long strip with the width of about 2 centimeters and the length of about 15 centimeters, soaking fine grass mud in the long strip, wrapping the long strip at the joint of the sealed primary and secondary tanks, drying in the sun, and finally burning in the stove;
4) feeding into a furnace: putting the prepared three-leg iron frame into a large basin for supporting, then putting the basin bottom on the basin frame with a central opening, putting the primary and secondary tank mother tanks with sealed openings downwards, penetrating three quarters of the primary and secondary tank mother tanks from the basin openings, using grass mud to tightly mud the joints of the tanks, stably supporting the three-leg iron frame in the center of a cold basin, putting the prepared fine sand into the basin with the opening, putting the sand surface to be more than three centimeters above the seal of the primary and secondary tanks, pressurizing and compacting, and burning;
5) scouring: the duration of the fire is divided into three steps, each step is 60 minutes, the first step: preferably, the slow fire is implemented by burning part of charcoal to red, clamping a plurality of charcoal blocks to be placed on the bottom of the sub-tank, then placing the rest of the red charcoal around the sub-tank, adding part of the burnt charcoal, tightly enclosing the sub-tank, and naturally burning for 60 minutes, namely, turning to the second step: adding charcoal to the red charcoal on the bottom and around the son tank while continuously blowing a fan of cattail to assist the fire for 60 minutes, and performing a third step: adding charcoal to the bottom and periphery of the sub-tank until the tank does not leak, naturally burning for 30 minutes, stopping adding charcoal, and naturally cooling until the rest fire is burnt out;
6) taking pills: and lightly moving the tripod together with the red lead tank out of the water basin, placing the tripod in a lying position, removing sand in the basin and mud at the joint of the basin and the red lead tank, moving the tripod out of the red lead tank, horizontally unsealing, and taking out white crystals in the mother tank and the son tank to obtain the white Jiangtdan.
Note: the whole refining process is carried out in extremely quiet environment, if the bare feet walk on the ground, the charcoal is added, and the user needs to slightly lift and move to prevent the shock of the red pot, so that the tire is collapsed or mercury is removed, and the drug effect is greatly reduced.
The traditional Chinese medicine used by the invention has the following medicinal properties:
mercury: has analgesic effect.
Alum: [ FUNCTIONS ] can resolve phlegm, eliminate dampness, check diarrhea, stop bleeding, remove toxicity and kill parasites. Treating epilepsy, pharyngitis, acute and chronic saliva accumulation, hepatitis, jaundice, yellow swelling, gastric ulcer, duodenal ulcer, uterine prolapse, leucorrhea, dysentery, epistaxis, aphtha, sore, hemorrhoid, scabies, tinea, water, fire, and insect injury.
And (3) nitrate: bitter and cold in flavor and has the functions of softening hardness to dissipate stagnation, reducing swelling and relieving pain
The salt has the effects of clearing away fire, cooling blood, removing toxicity, lowering adverse qi and relieving pain.
Melanterite: it is prismatic crystal or granular translucent body, belongs to mineral of sulfate mineral melanterite, is collected, and is removed of impurities, and is unprocessed or calcined with vinegar, and is green, mainly contains ferrous sulfate, hard and crisp in quality, odorless, astringent and sweet in taste, sour and cool in nature and enters liver and spleen channels.
Cinnabar: [ PROPERTIES AND FLAVOUR ] sweet, cool and toxic. [ GUIJING ] enters the heart meridian. [ FUNCTIONS ] can soothe the nerves, arrest convulsion, improve eyesight, and remove toxicity. For mania, palpitation, restlessness and insomnia: vertigo, dizziness, swollen toxicity, sores and ulcers, scabies and tinea.
Borax [ functional indications ] can clear heat, dissolve phlegm, detoxify and preserve corrosion. It is used to treat sore throat, aphtha of the mouth and tongue, conjunctival congestion, nebula, choking sensation in the throat, cough, and thick phlegm.
Realgar: [ PROPERTIES AND WESTERN ] is pungent, bitter, warm and toxic. [ GUIJING ] enters heart, liver and stomach meridians. [ FUNCTIONS ] can eliminate dampness, dispel pathogenic wind, kill parasites, and remove toxic substances. Treating scabies, tinea pedis, carbuncle, ulcerative gingivitis, herpes zoster, tetanus, snake worm, crab injury, bromhidrosis, ecthyma, asthma, pharyngitis, epilepsy, and hemorrhoid complicated with fistula.
The pearl powder is sweet and salty in taste and cold in nature; it enters heart and liver meridians. Tranquilization and arresting convulsion; clearing liver and improving vision; remove toxicity and promote tissue regeneration.
Powder: also called lead powder, belongs to mineral pigments. The prescription also belongs to monarch drugs, and cold can relieve heat toxin, so the cold is treated for curing cold stings caused by anger, sores and toxins. It is sweet and pungent in nature. Enter the qi system of foot-shaoyin channel. The chemical components of the lead carbonate are basic lead carbonate prepared by processing lead, and the lead carbonate is preferably white, fine and free of impurities.
The leukopenia pill provided by the invention is prepared from raw materials including mercury, alum, potassium nitrate, salt, melanterite, cinnabar, borax, realgar, pearl powder and official powder, is used for treating carbuncle-abscess, back-on furunculosis, dorsal furunculosis diffusion, sore head collapse, necrosis difficult to fall off, ulceration in sores for a long time without perforation, has a remarkable effect in treating the diseases by traditional Chinese medicine, is short in course of disease, difficult to relapse and obvious in advantage, adopts less medicinal flavors, and ensures that the effects of various medicinal materials in the aspect of scabies are mutually enhanced through reasonable compatibility, so that an obvious synergistic effect is shown.
Detailed Description
The present invention will be further described with reference to the following examples.
EXAMPLE 1 preparation of hydrargyrum chloratum Compositum
The formula is as follows: 30g of mercury, 24g of alum, 20g of potassium nitrate, 10g of salt, 10g of melanterite, 20g of cinnabar, 10g of borax, 5g of realgar, 20g of pearl powder and 20g of official powder.
The preparation method comprises the following steps: 1) testing the pot: the primary and secondary tanks are checked once, and water is added for testing if necessary, and the base tire can be carried out if no leakage hole exists and the opening is not tight;
2) a tire is seated: the method comprises grinding Alumen, Sal Nitri, Melanteritum, Cinnabaris, Borax, Realgar, Margarita powder, and hydrocerussitum respectively, adding hydrargyrum, grinding to a degree of no star, making into medicinal blank, dividing the medicinal blank into three parts, placing the medicinal blank in the side of the bottom of the sub-tank, tilting the tank to 45 deg.C, placing the tank at the fire side of the fire, baking until the medicinal blank melts, turning over, placing the sub-tank into one part of the medicinal blank after rotating the sub-tank at 120 deg.C until the medicinal blank solidifies in the sub-tank, rotating the tank at 120 deg.C, placing the last part of the medicinal blank, standing the sub-tank until the medicinal blank solidifies completely in the tank, covering the main tank on the sub-tank, opening the main tank, checking, and if there is no water gas in the main tank, making a tire, then placing the tire at the side of the fire, opening the main tank until no water gas is in order to be baked, if yellow smoke emerges from the pot, the mercury is removed, and the efficacy of the refined smoke is greatly reduced and poisoned;
3) and (3) can sealing: tightly closing two openings of the primary and secondary tanks, regulating the shape of mud with water by using prepared calcined gypsum powder and salt powder, fixing the primary and secondary tanks by one hand, plugging the mud into the joint of the primary and secondary tanks by the other hand, compacting and sealing, smearing water by hands to smooth the joint, drying in the sun or drying beside a stove, checking whether a crack exists, folding the crack into a long strip with the width of about 2 centimeters and the length of about 15 centimeters, soaking fine grass mud in the long strip, wrapping the long strip at the joint of the sealed primary and secondary tanks, drying in the sun, and finally burning in the stove;
4) feeding into a furnace: putting the prepared three-leg iron frame into a large basin for supporting, then putting the basin bottom on the basin frame with a central opening, putting the primary and secondary tank mother tanks with sealed openings downwards, penetrating three quarters of the primary and secondary tank mother tanks from the basin openings, using grass mud to tightly mud the joints of the tanks, stably supporting the three-leg iron frame in the center of a cold basin, putting the prepared fine sand into the basin with the opening, putting the sand surface to be more than three centimeters above the seal of the primary and secondary tanks, pressurizing and compacting, and burning;
5) scouring: the duration of the fire is divided into three steps, each step is 60 minutes, the first step: preferably, the slow fire is implemented by burning part of charcoal to red, clamping a plurality of charcoal blocks to be placed on the bottom of the sub-tank, then placing the rest of the red charcoal around the sub-tank, adding part of the burnt charcoal, tightly enclosing the sub-tank, and naturally burning for 60 minutes, namely, turning to the second step: adding charcoal to the red charcoal on the bottom and around the son tank while continuously blowing a fan of cattail to assist the fire for 60 minutes, and performing a third step: adding charcoal to the bottom and periphery of the sub-tank until the tank does not leak, naturally burning for 30 minutes, stopping adding charcoal, and naturally cooling until the rest fire is burnt out;
6) taking pills: and lightly moving the tripod together with the red lead tank out of the water basin, placing the tripod in a lying position, removing sand in the basin and mud at the joint of the basin and the red lead tank, moving the tripod out of the red lead tank, horizontally unsealing, and taking out white crystals in the mother tank and the son tank to obtain the white Jiangtdan.
EXAMPLE 2 preparation of hydrargyrum chloratum Compositum
The formula is as follows: 28g of mercury, 24g of alum, 20g of potassium nitrate, 10g of salt, 10g of melanterite, 20g of cinnabar, 10g of borax, 5g of realgar, 25g of pearl powder and 20g of official powder.
The preparation method is the same as example 1.
EXAMPLE 3 preparation of hydrargyrum chloratum Compositum
The formula is as follows: 31g of mercury, 24g of alum, 20g of potassium nitrate, 10g of salt, 10g of melanterite, 20g of cinnabar, 10g of borax, 5g of realgar, 25g of pearl powder and 20g of official powder.
The preparation method is the same as example 1.
The observation of the curative effect of a specific case:
experimental example 1
The patient Li A, male, 49 years old, single county Yanghouxiang, will see a doctor 7 months and 5 days in 2015
The main complaints are: the skin of the patient below the knee joints of both lower limbs blackens with several scabs for half a year, aggravating for one month
The current medical history: the patient feels heavy and fatigue in the two lower limbs during the housework and farming season half a year ago, and gets worse in the afternoon, and the ultrasonic wave shows that the strands and branches of the two lower limbs are obviously narrow when the patient is treated in a local people hospital. The diagnosis is occlusive arteriosclerosis, the symptoms are not relieved after three months of treatment by medicaments such as simvastatin serving as a blood fat reducing medicament, vitamin C, nifedipine serving as a vasodilator, nicotinic acid and the like, the skin is dark and black from the inner sides of thighs at two sides to knee joints, the ulcer is accompanied with severe pain and fever, particularly at night, the amputation of the lower limbs is suggested to be performed in time to prevent the disease from spreading, and the patients are reluctant to perform the operation due to poor economic capability, so the treatment is performed in our hospital.
History of the past: past ten years with history of hypertension
Personal history: pinsu spicy food
Family history: is free of
Physical examination: t: 38.0P: 75 times/min R: 150/90mmHg, spiritual, dietetic, clear language, cooperative diagnosis, round and big pupils, no abnormality of superficial lymph nodes of the whole body, percussion and clear sound of the two lungs, normal respiration, no rale, normal heart point pulsation and heart voiced sound boundary, regular rhythm, no noise, soft abdomen, no tenderness, percussion pain and rebound pain. Liver, spleen and kidney were not monitored. The spleen and kidney areas on both sides have no pressure pain or percussion pain. The spine is normal, the skin is blackened above the ankle joints below the knee joints on the inner sides of the lower legs on both sides, three broad beans are arranged on the left side, two broad beans are arranged on the right side, the scabbing effect is not obvious in the boundary with the normal tissues, and the tenderness is obvious.
And (3) diagnosis: gangrene
After the patient is hospitalized, the tongue of the patient is yellow, thick and greasy, the pulse is wiry and unsmooth, the patient usually suffers cold and water involvement due to dry farming activities, cold coagulation and blood stasis are caused by cold and dampness, the channels and collaterals are blocked, so the pain is severe, the dampness is yin pathogen, the spleen yang is easily injured, the transportation and transformation are lost, the qi and blood are deficient, the limbs are not nourished, and the blood vessels are not full, so the skin is blackened and crusted and necrotized. The decoction is prepared by adding and subtracting Yang tonifying five-medicine decoction and peach red four-medicine decoction for oral administration, one dose is taken every day, the scorched scab part is stained with white blood-reducing pill which is a self-made preparation, three times a day, and the rest parts are externally smeared with blood-activating stasis-removing paste for three times a day for continuous ten days. After ten days, the boundary of the scorched and scabbed part and the surrounding skin tissue is clear and slightly caulked, purulent secretion is discharged, the color of the skin tissue of the original blackened part is changed into grey black, patients complain of slight dizziness, dry mouth and eye dryness, selfheal, rhizoma gastrodiae and radix ophiopogonis are added along with the original prescription, one dose is taken every day, the scabbed part is still dipped with the hydrargyrum chloratum bunge for three times every day, and the application lasts for ten days. After ten days, the patients are subjected to a repeated diagnosis, the gray and black skin color of the affected part is continuously lightened, scab parts are completely removed, the color of the plane is light red, the low fever is already reduced, the medicine is taken above the affected part, one dose is taken every day, the whitening and blood-reducing pill is reduced, and all the scab removal parts are externally smeared with the blood circulation-promoting and blood stasis-removing ointment three times a day for ten days. After ten days, the patients are retested, the skin where the scabs are cast off grows flat and has the surrounding tissues and shows light red, the original color of the original blackened skin is basically recovered, the patients are ordered to stop taking the traditional Chinese medicine orally, and the two lower limbs are externally smeared with the blood circulation promoting and blood stasis removing ointment for ten days to consolidate the treatment. The patients are diagnosed again after one month, the symptoms do not relapse, and all the skins recover well.
Experimental example 2
Patient Wangzhi, male, 55 years old, Shima Zhenhao Yancun in Jinxiang county
The main complaints are: numbness of both lower limbs, indirect slope for two years, dark burning and scabbing of toes, and severe pain.
The current medical history: the patients are dry at home and live in the farming two years ago, the sudden sensation of pain and numbness of the ankles of the lower limbs are relieved with cold, and the pain is aggravated after the patients are tired in cold, especially the tail ends of the toes. The disease is relieved after nearly half a year by treating the thromboangiitis obliterans with a vasodilator and an anti-inflammatory analgesic (the specific medicine is not used in detail) in county-level hospital, the disease of a patient relapses before two months, the effect is poor after the medicine is used, the patient is recommended to perform double lower limb amputation, and the patient does not agree to the treatment and can treat the disease at all times.
History of the past: the history of diabetes is eighteen years, the history of hypertension is ten years, and no trauma history exists.
Personal history: neutral addiction wine
Family history: is free of
Physical examination: t: 36.7P: 75 times/min R: 160/90mmHg, the patient has painful expression, sits with knees, has two pupils in a big circle, has no abnormality of superficial lymph nodes of the whole body, has two lungs for percussion and clear sound, has normal breathing and no rale, has normal heart apex pulsation and heart voiced sound boundary, is aligned, has no murmur, has soft abdomen, no tenderness, percussion pain and rebound pain. Liver, spleen and kidney were not monitored. The spleen and kidney areas on both sides have no pressure pain or percussion pain. The spine is normal, the skin at the tail ends of the two hands is grey black, the muscles below the knee joints at the two sides are atrophic, the fur is dry, the ankle joint swelling is obvious, the skin at the instep is black and white, the fifth toe of the right foot is deficient, the ulcerated sore surface with the area of about 1 centimeter is formed, and a small amount of clear and thin secretion but no red swelling is formed. The toe ends of the remaining toes all had black ulceration with varying degrees of scabbing, with cold skin below the joint of the two knees, especially short at the end.
And (3) diagnosis: gangrene
After the patient is hospitalized, the tongue of the patient is pale and white, the pulse is wiry and thin, the patient is plain and has emaciation, the spleen qi is not healthy, the liver and the kidney are insufficient, the patient is attacked by damp evil for a long time, qi and blood are stagnated in the veins and blocked, and the skin at the tail end is not nourished, so that the skin is numb and blackened, and the patient is easy to get on yang qi due to cold into yin evil, and the pain is severe and aggravated at night. The medicine is prepared by adding yang harmonizing decoction for warming yang, dispelling cold, promoting blood circulation and dredging collaterals, applying the preparation to the fifth toe deficiency such as ulcer part, and applying the preparation to the crusted parts of the other toes, which are difficult to fall off, on the spot with Plumbum preparatium, and applying the ointment for promoting blood circulation and removing blood stasis three times a day for ten days. In two diagnosis days after ten days, the fifth toe ulcer part of the patient is basically healed, grows flat with the surrounding tissues and is light red, and the remaining scab parts of the toes are separated from the normal tissues by about two thirds and still have pain. The antler glue is reduced on the basis of the original oral traditional Chinese medicine, the antler frost with better effects of promoting blood circulation and astringing and stopping bleeding is used, one dose is taken every day, then the scabbed part is stained with the white-reducing pill, and the ointment for promoting blood circulation and removing blood stasis is externally applied for three times every day and is used for ten days continuously. After ten days, pain disappears, scabbed parts of toes completely fall off, dark red granulation tissues are exposed, but the growth is slow, and patients do not walk for a long time, have poor appetite and are not affected by yang harmonizing decoction due to dialectical reasons. In the four diagnostic methods after ten days, the patient can sleep at night, the sore surface is healed completely, the dorsum pedis artery is slightly reachable, the patient walks as usual, all external medicines are stopped, and ten doses of eight-treasure decoction are taken one dose a day to strengthen the constitution after the disease. The follow-up visit after one month has no recurrence.
The specific embodiments of the present invention should not be construed as limiting the invention, and all similar constructions and modifications utilizing the same are intended to be included within the scope of the present invention.

Claims (1)

1. The white Jiangtangdan is characterized in that: is prepared from the following raw material medicaments: 30g of mercury, 24g of alum, 20g of potassium nitrate, 10g of salt, 10g of melanterite, 20g of cinnabar, 10g of borax, 5g of realgar, 20g of pearl powder and 20g of official powder.
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