CN106861020A - A kind of fluorography moves under water puncture seal wire - Google Patents

A kind of fluorography moves under water puncture seal wire Download PDF

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Publication number
CN106861020A
CN106861020A CN201710153073.8A CN201710153073A CN106861020A CN 106861020 A CN106861020 A CN 106861020A CN 201710153073 A CN201710153073 A CN 201710153073A CN 106861020 A CN106861020 A CN 106861020A
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CN
China
Prior art keywords
seal wire
fluorography
under water
cavity
moves under
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Granted
Application number
CN201710153073.8A
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Chinese (zh)
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CN106861020B (en
Inventor
史均宝
孙建军
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Beijing Ju Jingruisheng Medical Science And Technology Co Ltd
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Beijing Ju Jingruisheng Medical Science And Technology Co Ltd
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Priority to CN201710153073.8A priority Critical patent/CN106861020B/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09Guide wires
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0021Catheters; Hollow probes characterised by the form of the tubing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M2025/0008Catheters; Hollow probes having visible markings on its surface, i.e. visible to the naked eye, for any purpose, e.g. insertion depth markers, rotational markers or identification of type
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09Guide wires
    • A61M2025/09133Guide wires having specific material compositions or coatings; Materials with specific mechanical behaviours, e.g. stiffness, strength to transmit torque

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

Moved under water puncture seal wire the invention discloses a kind of fluorography, including puncture guidewire body, the cavity being arranged on inside the puncture guidewire body head end, connect the cavity and puncture passage at the top of guidewire body head end, connect the cavity with multiple micropores of puncture guidewire body outer surface and the plug of the closing passage.The present invention has visual effect, being capable of timely monitor autofluorescence seal wire probe, accurate grasp seal wire placing direction and position, it is to avoid seal wire is surprisingly broken.

Description

A kind of fluorography moves under water puncture seal wire
Technical field
Moved under water puncture seal wire the present invention relates to a kind of fluorography, belong to Minimally Invasive Surgery instrument field.
Background technology
The interventional minimally-invasive operation of the modern times such as arteria carotis, cerebral artery, coronary artery bracket and embolism is required for being punctured into by moving under water dynamic The seal wire of arteries and veins reaches the operation such as the site for needing treatment, deep venouspuncture, Pacemaker implantation or haemodialysis to be needed by moving under water The seal wire for puncturing into vein reaches specified anatomical position.But under the skin between face, flesh traveling, with row beside bone, shuttle Seal wire between splanchnocoel internal organs, X-ray is relied primarily at present makes its moment visual.
But because fearing the canceration that x-ray Excess free enthalpy may induce, the doctor or technician of operation will not select unless it is absolutely necessary " stepping on a pin " perspective is selected, is worn by rich experience is blind, but the vascular system such as arteriovenous of human body exists and varies Variation, and in different segment, have different branch or category branch, have the diverticulum class trap that is difficult to expect, so, operator Often " go astray ", it is impossible to arrival predetermined site of achieving one's goal.Current solution is withdrawn from and put again pipe or select other Vascular path, certainly will so increase the labour intensity of operator and the degree of injury of patient.Most terrible consequences is pneumothorax, abdominal cavity Bleeding, arteriovenous rupture etc., also occur the phenomenon in guide wire fragment, Remained mass.
The content of the invention
Technical problem:The present invention provides a kind of with visual effect, being capable of timely monitor autofluorescence seal wire probe, the accurate palm Hold seal wire placing direction and position, it is to avoid the fluorography that seal wire is surprisingly broken moves under water puncture seal wire.
Technical scheme:Fluorography of the invention moves under water puncture seal wire, including punctures guidewire body, is arranged on described wearing Cavity inside thorn guidewire body head end, connect the cavity and the passage at the top of puncture guidewire body head end, connect the sky Chamber and the multiple micropores for puncturing guidewire body outer surface and the plug of the closing passage.
Further, in the present invention, screw thread is provided with the passage, the plug is to install blocking channel by screw thread Micro screw.
Further, in the present invention, the fluorescent material in the cavity filled with particle diameter more than micro-pore diameter.
Further, in the present invention, the fluorescent material is Photosensitive fluorescent material, is swashed during body temperature more than 35 degrees Celsius Fluoresce.
Further, in the present invention, the fluorescent material has pressure sensibility, exceedes in extraneous hydrostatic pressing pressure During 60mmHg, the fluorescence of another wavelength can be excited.
The present invention by traditional move under water puncture seal wire, seal wire head end be built-in blue or red autofluorescence occurring source and it is small-sized from Fluorescence monitoring device is constituted, and external setting excites and recognize autofluorescence handle sampling device, and when using, seal wire is all infiltrated in vein In (or artery), the hydrostatic pressing in vein (or artery) can be directly passed to fluorescent grain by multiple micropores.
Beneficial effect:The present invention compared with prior art, with advantages below:
1. visual effect:In puncture process of moving under water, presently used conventional guide wires enter it is subcutaneous after, operation must be fully relied on The clinical manipulation experience and skill of person, it is not visible.Seal wire of the present invention is such as used, operator can be appreciated that seal wire has arrived there at any time, It is like the shadow following the person, reach visual effect.
2. it is accurate to grasp seal wire direction and position:Operation at present is only inserted in artery, vein or atrium seal wire with feel, But whether the direction that seal wire is inserted tries to go south by driving the chariot north or whether seal wire inserts reach specified location, all substantially estimates, it is impossible to It is accurate to grasp, so just having the adverse consequences that seal wire is strayed into other lacunas;With the present invention, can accurately grasp seal wire and put Whether the direction for the entering position whether correct, seal wire is inserted is suitable.
3. precisely grasp and enter predetermined vascular system:Using conventional guide wires, often want to be strayed into artery, result Vein;Want into vein but be strayed into the adverse consequences of artery, more seriously, seal wire does not find in time after being strayed into;With this hair Bright seal wire, it is different using the fluorescence color that is excited after different pressures is experienced, seal wire into predetermined vascular system can be precisely grasped, Even if being strayed into, also in time reminding operator to terminate further maloperation.
4. meet with when getting stuck and shoot the arrow at the target:Met obstructions in operating process or other fortuitous events emergency processing, at present Conventional guide wires will be positioned by x-ray or B ultrasonic, and corrective operation is blindly to withdraw from entirely or disorderly disclose;Using the visualization of seal wire of the present invention Different color developing effects in effect, vascular, it is not necessary to raying or other measures, so that it may know seal wire there occurs bending or It is strayed into other lacunas;When such as needing adjustment seal wire direction and position, it is not necessary to blindly withdraw from entirely or disorderly disclose, can accomplish that what is had puts Arrow ground solves the problem that gets stuck.
5. the accident of seal wire fractures:Because the problems such as getting stuck of experience in above-mentioned puncture process, if further roughly by mistake , often there is the adverse consequences that conventional guide wires surprisingly fracture, in order to find the seal wire head end of fracture, it is often necessary to borrow in operation X-ray inspection many times or B ultrasonic positioning, bring huge body and mind to hit to patient;Using seal wire of the present invention, (1) is not easy The situation that existing seal wire is surprisingly broken, (2) are even if fracture, effect of visualization accurately understand seal wire head end position.
The actual configuration of human vasculature is further understood that, make a variation the ratio for occurring, and is that the development of medical science is done Go out contribution.
Brief description of the drawings
Fig. 1 is the sequential schematic that two kinds of fluorescent grains are excited;
Fig. 2 is structural representation of the invention.
Specific embodiment
With reference to embodiment and Figure of description, the present invention is further illustrated.
In embodiments of the invention, 900 microns of positions in the seal wire head end of the microns of diameter 970, built-in diameter is about 500 microns of cavity, the micropore of multiple 50 micron pore sizes and seal wire outer surface communicate;Build-in cavities and seal wire head end have a diameter of 400 microns of screw channel, this passage is used to load fluorescent material, passage can with 200 microns of diameter, be about 300 microns micro- Screw tight closure.Autofluorescence material can be accommodated in cavity to be put into, then tight with screw closure, autofluorescence material grainses are big In 50 microns, it is ensured that autofluorescence appears light from 50 micrometer Millipores, but autofluorescence material does not leak;
When external handle works, itself can shroud special light curtain in skin surface, and can specificity excite from glimmering Stimulative substance is luminous, the luminous point of autofluorescence can clearly develop in handle light curtain, and naked eyes are distinguishable;Above-mentioned seal wire is all in 3D metallic prints Integration is completed under powdering technology.
Built-in autofluorescence material is special material, need to meet following condition:It is nontoxic to human body, not with blood flow rush Brush and soak and be released into blood, less than 35 degree room temperature autofluorescence materials and excite fluorescence by not discharging fluorescence, more than 35 degree body temperature Release;Specific pressure experience fluorescence will not be excited when intravenous traveling, pressure are in below 60mmHg, after being strayed into artery, sense It is stressed and excite specific pressure fluorescence more than 60mmHg, the fluorescence of seal wire release, can only be special in specific wave-length coverage Reception device in wavelength range is recognized and shown.
Fluorography of the present invention move under water puncture seal wire specific temperature control and pressure regulation autofluorescence mechanism description it is as follows:
LASER Excited Fluorescence, influenced by ambient temperature, different with environment temperature, the wavelength of fluorescence intensity for exciting is different.Ring Computer Corp. of border temperature activated fluorescence intensity is as follows:
I=I0C φ ε
I0 (Wm-3) represents incident intensity flux, and C (kgm3) represents fluorescence intensity, and Φ represents quantum efficiency, and ε is represented Fluorescent absorption coefficient.
If fluorescent dye and temperature proportional, then the intensity of light means the function of temperature.With formula below Carry out measurement temperature, but there is incident flux intensity to the restricted of measured condition depended.
IA represents the intensity of temperature sensitivity A fluorescence channels, and IB represents the intensity that temperature loses quick property B fluorescence channels;IA with Environment temperature and change, IB is not influenced by ambient temperature.If only using temperature sensitivity fluorescence, the more than fluorescence of output is strong The function of the function of degree and also environment temperature.Here Φ B ε B are almost the constant of a temperature change, the ripple of IA and IB Length is different.
The luminous intensity of double fluorescence changes because of temperature and pressure intensity, starts to excite fluorescence to send out during up to more than 35 degree body temperature It is raw, that is, temperature sensitive (TSP);When seal wire head bears more than 60mmHg arteriosity pressure, Activate pressure sense at once By type fluorescence (PSP).
Above-described embodiment is only the preferred embodiment of the present invention, it should be pointed out that:For the ordinary skill of the art For personnel, under the premise without departing from the principles of the invention, some improvement and equivalent can also be made, these are to the present invention Claim be improved with the technical scheme after equivalent, each fall within protection scope of the present invention.

Claims (5)

1. a kind of fluorography moves under water puncture seal wire, it is characterised in that the puncture seal wire includes puncturing guidewire body, is arranged on The cavity punctured inside guidewire body head end, connect the cavity and the passage at the top of puncture guidewire body head end, connect The cavity and the multiple micropores for puncturing guidewire body outer surface and the plug of the closing passage.
2. fluorography according to claim 1 moves under water puncture seal wire, it is characterised in that be provided with spiral shell in the passage Line, the plug is the micro screw that blocking channel is installed by screw thread.
3. fluorography according to claim 1 and 2 moves under water puncture seal wire, it is characterised in that filling in the cavity There is particle diameter more than the fluorescent material of micro-pore diameter.
4. fluorography according to claim 3 moves under water puncture seal wire, it is characterised in that the fluorescent material is photosensitive Type fluorescent material, fluorescence is excited more than 35 degrees Celsius during body temperature.
5. fluorography according to claim 4 moves under water puncture seal wire, it is characterised in that the fluorescent material has pressure Power sensitiveness, when extraneous hydrostatic pressing pressure is more than 60mmHg, can excite the fluorescence of another wavelength.
CN201710153073.8A 2017-03-15 2017-03-15 Fluorescence self-development diving puncture guide wire Active CN106861020B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710153073.8A CN106861020B (en) 2017-03-15 2017-03-15 Fluorescence self-development diving puncture guide wire

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CN201710153073.8A CN106861020B (en) 2017-03-15 2017-03-15 Fluorescence self-development diving puncture guide wire

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CN106861020B CN106861020B (en) 2024-02-20

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020087098A1 (en) * 2000-10-30 2002-07-04 Jun Iwami Medical long object and method for producing the same
US20030229298A1 (en) * 2002-03-25 2003-12-11 Terumo Kabushiki Kaisha Guide wire
US20150148665A1 (en) * 2012-06-01 2015-05-28 National University Corporation Kochi University Medical product emitting near-infrared fluorescence and medical product usage status checking apparatus
CN204500704U (en) * 2015-03-12 2015-07-29 湖南埃普特医疗器械有限公司 A kind of mapping micro-wire
CN105018082A (en) * 2015-07-10 2015-11-04 上海纳米技术及应用国家工程研究中心有限公司 Method for preparing carbon quantum dot labeled probe for silk fibroin extracted cell development
CN207137137U (en) * 2017-03-15 2018-03-27 北京聚精瑞生医疗科技有限公司 Fluorography, which moves under water, punctures seal wire

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020087098A1 (en) * 2000-10-30 2002-07-04 Jun Iwami Medical long object and method for producing the same
US20030229298A1 (en) * 2002-03-25 2003-12-11 Terumo Kabushiki Kaisha Guide wire
US20150148665A1 (en) * 2012-06-01 2015-05-28 National University Corporation Kochi University Medical product emitting near-infrared fluorescence and medical product usage status checking apparatus
CN204500704U (en) * 2015-03-12 2015-07-29 湖南埃普特医疗器械有限公司 A kind of mapping micro-wire
CN105018082A (en) * 2015-07-10 2015-11-04 上海纳米技术及应用国家工程研究中心有限公司 Method for preparing carbon quantum dot labeled probe for silk fibroin extracted cell development
CN207137137U (en) * 2017-03-15 2018-03-27 北京聚精瑞生医疗科技有限公司 Fluorography, which moves under water, punctures seal wire

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