CN106861020B - Fluorescence self-development diving puncture guide wire - Google Patents
Fluorescence self-development diving puncture guide wire Download PDFInfo
- Publication number
- CN106861020B CN106861020B CN201710153073.8A CN201710153073A CN106861020B CN 106861020 B CN106861020 B CN 106861020B CN 201710153073 A CN201710153073 A CN 201710153073A CN 106861020 B CN106861020 B CN 106861020B
- Authority
- CN
- China
- Prior art keywords
- guide wire
- fluorescence
- cavity
- seal wire
- puncture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 230000009189 diving Effects 0.000 title description 3
- 239000000463 material Substances 0.000 claims description 8
- 230000036760 body temperature Effects 0.000 claims description 4
- 239000002245 particle Substances 0.000 claims description 4
- 230000002706 hydrostatic effect Effects 0.000 claims description 2
- 238000009434 installation Methods 0.000 claims description 2
- 230000035945 sensitivity Effects 0.000 claims description 2
- 230000000007 visual effect Effects 0.000 abstract description 6
- 239000000523 sample Substances 0.000 abstract description 2
- 238000007789 sealing Methods 0.000 abstract description 2
- 238000003780 insertion Methods 0.000 abstract 1
- 230000037431 insertion Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 description 9
- 210000001367 artery Anatomy 0.000 description 6
- 210000003462 vein Anatomy 0.000 description 6
- 230000005284 excitation Effects 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 230000002792 vascular Effects 0.000 description 3
- 230000002411 adverse Effects 0.000 description 2
- 230000004907 flux Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 230000000149 penetrating effect Effects 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 210000005166 vasculature Anatomy 0.000 description 2
- 241001391944 Commicarpus scandens Species 0.000 description 1
- 206010013554 Diverticulum Diseases 0.000 description 1
- 208000005189 Embolism Diseases 0.000 description 1
- 241001484259 Lacuna Species 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000004872 arterial blood pressure Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000001715 carotid artery Anatomy 0.000 description 1
- 210000001627 cerebral artery Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000007850 fluorescent dye Substances 0.000 description 1
- 238000002594 fluoroscopy Methods 0.000 description 1
- 238000001631 haemodialysis Methods 0.000 description 1
- 210000002837 heart atrium Anatomy 0.000 description 1
- 230000000322 hemodialysis Effects 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000001404 mediated effect Effects 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000012806 monitoring device Methods 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 201000003144 pneumothorax Diseases 0.000 description 1
- 238000007639 printing Methods 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000000246 remedial effect Effects 0.000 description 1
- 238000009991 scouring Methods 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M2025/0008—Catheters; Hollow probes having visible markings on its surface, i.e. visible to the naked eye, for any purpose, e.g. insertion depth markers, rotational markers or identification of type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/09133—Guide wires having specific material compositions or coatings; Materials with specific mechanical behaviours, e.g. stiffness, strength to transmit torque
Abstract
The invention discloses a fluorescence self-development submerged puncture guide wire, which comprises a puncture guide wire body, a cavity arranged in the head end of the puncture guide wire body, a channel for communicating the cavity with the top of the head end of the puncture guide wire body, a plurality of micropores for communicating the cavity with the outer surface of the puncture guide wire body and a plug for sealing the channel. The invention has visual effect, can timely monitor the self-fluorescence guide wire probe, accurately grasp the insertion direction and position of the guide wire, and avoid accidental breakage of the guide wire.
Description
Technical Field
The invention relates to a fluorescence self-development submerged puncture guide wire, belonging to the field of minimally invasive surgical instruments.
Background
Modern mediated minimally invasive operations such as carotid artery, cerebral artery, coronary stent and embolism all need to reach the site to be treated by means of a guide wire penetrating into the artery in a submerged way, and operations such as deep vein catheterization, pacemaker implantation or hemodialysis need to reach the designated anatomical position by means of a guide wire penetrating into the vein in a submerged way. But the guide wire which runs under the skin and between the muscles, accompanies the bones and shuttles between the organs of the pleuroperitoneal cavity is mainly made to be instantly visible by means of X-ray at present.
However, since the doctor or technician who is afraid of excessive X-ray intake may induce canceration, he or she must not choose to see "step on the foot" for fluoroscopy, and most of them are blind-worn by means of abundant experience, but vascular systems such as arteries and veins of the human body have various variations, and have different branches or branches in different sections, and have unexpected diverticulum traps, so that the operator often cannot reach the predetermined site by "misentering the way". The current solution is to withdraw the repositioning tube, or select an additional vascular access, which tends to increase the labor intensity of the operator and the extent of patient trauma. The most terrible consequences are pneumothorax, abdominal bleeding, arteriovenous rupture, etc., and the occurrence of broken guide wires and residual body.
Disclosure of Invention
Technical problems: the invention provides a fluorescent self-developing submerged puncture guide wire which has a visual effect, can timely monitor an autofluorescence guide wire probe, accurately grasp the placement direction and the placement position of the guide wire and avoid accidental breakage of the guide wire.
The technical scheme is as follows: the invention discloses a fluorescence self-development submerged puncture guide wire, which comprises a puncture guide wire body, a cavity arranged in the head end of the puncture guide wire body, a channel for communicating the cavity with the top of the head end of the puncture guide wire body, a plurality of micropores for communicating the cavity with the outer surface of the puncture guide wire body and a plug for sealing the channel.
In the invention, a thread is arranged in the channel, and the plug is a micro screw which is used for plugging the channel through the thread installation.
Further, in the invention, the cavity is filled with fluorescent substances with particle diameters larger than the diameters of the micropores.
In the invention, the fluorescent substance is a photosensitive fluorescent material, and can excite fluorescence at a body temperature of 35 ℃ or higher.
Further, in the present invention, the fluorescent substance has pressure sensitivity, and when the external hydrostatic pressure exceeds 60mmHg, fluorescence of another wavelength is excited.
The invention is composed of a traditional submerged puncture guide wire, a blue or red autofluorescence generating source and a small autofluorescence monitoring device which are arranged in the end of the guide wire, and an excitation and identification autofluorescence handle-like device which is arranged outside the body.
The beneficial effects are that: compared with the prior art, the invention has the following advantages:
1. visual effect: in the submerged puncture process, the traditional guide wire used at present is completely dependent on the clinical operation experience and skill of an operator and cannot be seen after entering the skin. If the guide wire is used, an operator can know that the guide wire reaches the guide wire at any time, and the visual effect is achieved if the guide wire is in a shape of a shadow.
2. Accurately grasp the direction and position of the guide wire: at present, the operation is only to place the guide wire into an artery, vein or atrium by hand feeling, but whether the direction of placing the guide wire is south-beam north-track or whether the guide wire is placed at a designated position is estimated approximately and cannot be mastered accurately, so that the bad effect that the guide wire is wrongly placed into other lacuna exists; by the aid of the guide wire guiding device, whether the direction of the guide wire is correct or not and whether the position of the guide wire is proper or not can be accurately mastered.
3. Precise mastering access to the intended vasculature: with the traditional guide wire, the false entering of arteries and results into veins often happens; the adverse consequences of wanting to enter a vein, but misentering an artery, and more serious, the wrong entering of a guide wire is not found in time; by using the guide wire, the guide wire can be accurately mastered to enter a preset vascular system by using different fluorescence colors excited after sensing different pressures, and an operator can be timely reminded to terminate further misoperation even if the guide wire is wrongly entered.
4. The vector is put when encountering the shell: the emergency treatment of resistance or other unexpected situations is carried out in the operation process, the traditional guide wire is positioned by means of X-ray or B-ultrasonic at present, and the remedial operation is blind complete withdrawal or random poking; by applying the visual effect and the different color development effects in the vessel of the guide wire, the guide wire can be known whether the guide wire is bent or is wrongly put into other cavities without radiation or other measures; if the direction and the position of the guide wire are required to be adjusted, the problem of shell blocking can be solved in a vector manner without blind complete withdrawal or random poking.
5. Accidental breakage of the guidewire: because of the problems of clamping shells and the like in the puncture process, if the puncture is further crudely and misoperation, the adverse effect of accidental breakage of the traditional guide wire often occurs, and in order to find the broken guide wire head end, numerous X-ray inspection or B-ultrasonic positioning are often needed to be used, so that huge physical and psychological impact is brought to a patient; by applying the guide wire disclosed by the invention, (1) the situation that the guide wire is not easy to break accidentally is avoided, and (2) the position of the end of the guide wire is accurately known even if the guide wire breaks and the visual effect is achieved.
Further knowledge of the actual structure of the human vasculature, the rate at which the variation occurs, contributes to the development of medical science.
Drawings
FIG. 1 is a schematic diagram of a sequence of excitation of two fluorescent particles;
fig. 2 is a schematic structural view of the present invention.
Detailed Description
The invention is further illustrated by the following examples and the accompanying drawings.
In the embodiment of the invention, a cavity with the diameter of about 500 microns is arranged in a position of 900 microns in the end of a guide wire with the diameter of about 970 microns, and a plurality of micropores with the diameter of 50 microns are communicated with the outer surface of the guide wire; the built-in cavity and the end of the thread guide head are provided with a threaded channel with the diameter of 400 microns, the channel is used for filling fluorescent powder, and the channel can be tightly closed by a micro screw with the diameter of 200 microns and the length of about 300 microns. The cavity can contain the self-fluorescent substance, and then the self-fluorescent substance is tightly sealed by a screw, the particle size of the self-fluorescent substance is larger than 50 microns, so that the self-fluorescent light is ensured to penetrate out of the 50 micron micropores, but the self-fluorescent substance does not leak;
when the external handle works, a special light curtain can be covered on the skin surface, and the light spot capable of specifically exciting the self-fluorescent substance to emit light can be clearly developed in the handle light curtain, so that the light spot can be distinguished by naked eyes; the guide wires are all integrally finished under the 3D metal printing powder spreading technology.
The built-in self-fluorescent substance is a special material, and the following conditions are required to be satisfied: the fluorescent material is nontoxic and harmless to human body, does not release into blood along with blood flow scouring and soaking, does not release fluorescence from room temperature autofluorescent material below 35 ℃, and can excite fluorescence to release at body temperature above 35 ℃; when the pressure is below 60mmHg, the pressure will not excite specific pressure sensing fluorescence, after the pressure is mistakenly entered into the artery, the sensing pressure exceeds 60mmHg to excite specific pressure fluorescence, and the fluorescence released by the guide wire is in a specific wavelength range and can only be identified and displayed by a receiving device in the specific wavelength range.
The specific temperature control and pressure adjustment autofluorescence mechanism of the fluorescence autodevelopment diving puncture guide wire is described as follows:
the laser excites fluorescence, is influenced by the ambient temperature, and has different excitation wavelength intensities along with different ambient temperatures. The calculation company of the ambient temperature excitation fluorescence intensity is as follows:
I＝I0Cφε
i0 (Wm-3) represents the flux of incident light intensity, C (kg.m3) represents the fluorescence concentration, Φ represents the quantum efficiency, ε represents the fluorescence absorption coefficient.
If the fluorescent dye is proportional to the temperature, the intensity of the light means the function of the temperature. The following formula is used to measure temperature, but there is a limitation in the dependence of the intensity of the incident light flux on the measured environment.
IA represents the intensity of the temperature sensitive a fluorescent channel and IB represents the intensity of the temperature insensitive B fluorescent channel; IA varies with ambient temperature and IB is not affected by ambient temperature. If only temperature sensitive fluorescence is used, the output is not only a function of fluorescence intensity, but also a function of ambient temperature. Here Φb epsilon B is almost a constant of temperature change, and the wavelengths of IA and IB are different.
The luminous intensity of the double fluorescence changes due to the temperature and the pressure intensity, and the fluorescence starts to be excited when the body temperature reaches more than 35 ℃, namely the Temperature Sensitive (TSP); when the spinneret part receives arterial pressure of 60mmHg or more, pressure-sensitive fluorescence (PSP) is immediately excited.
The above examples are only preferred embodiments of the present invention, it being noted that: it will be apparent to those skilled in the art that several modifications and equivalents can be made without departing from the principles of the invention, and such modifications and equivalents fall within the scope of the invention.
Claims (2)
1. The utility model provides a fluorescence is from developing dive puncture seal wire, its characterized in that, this puncture seal wire includes puncture seal wire body, sets up cavity, the intercommunication that puncture seal wire body head end is inside cavity, the passageway at cavity and puncture seal wire body head end top, intercommunication cavity and a plurality of micropores of puncture seal wire body surface and the end cap of shutoff passageway, the cavity intussuseption is filled with the fluorescent material that the particle diameter is greater than the micropore diameter, the fluorescent material is photosensitive fluorescent material, excites fluorescence when above 35 degrees centigrade body temperature, the fluorescent material has pressure sensitivity, can excite the fluorescence of another wavelength when external hydrostatic pressure exceeds 60 mmHg.
2. The fluorous self-developing submerged entry nozzle guide wire of claim 1, wherein the channel is internally threaded and the plug is a micro screw that plugs the channel by threaded installation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710153073.8A CN106861020B (en) | 2017-03-15 | 2017-03-15 | Fluorescence self-development diving puncture guide wire |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710153073.8A CN106861020B (en) | 2017-03-15 | 2017-03-15 | Fluorescence self-development diving puncture guide wire |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106861020A CN106861020A (en) | 2017-06-20 |
| CN106861020B true CN106861020B (en) | 2024-02-20 |
Family
ID=59171792
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710153073.8A Active CN106861020B (en) | 2017-03-15 | 2017-03-15 | Fluorescence self-development diving puncture guide wire |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106861020B (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN204500704U (en) * | 2015-03-12 | 2015-07-29 | 湖南埃普特医疗器械有限公司 | A kind of mapping micro-wire |
| CN105018082A (en) * | 2015-07-10 | 2015-11-04 | 上海纳米技术及应用国家工程研究中心有限公司 | Method for preparing carbon quantum dot labeled probe for silk fibroin extracted cell development |
| CN207137137U (en) * | 2017-03-15 | 2018-03-27 | 北京聚精瑞生医疗科技有限公司 | Fluorography, which moves under water, punctures seal wire |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002136600A (en) * | 2000-10-30 | 2002-05-14 | Terumo Corp | Medical long body and method for manufacturing the same |
| JP4282979B2 (en) * | 2002-03-25 | 2009-06-24 | テルモ株式会社 | Guide wire |
| AU2013268518B2 (en) * | 2012-06-01 | 2017-06-15 | Dic Corporation | Medical product that emits near-infrared fluorescence and medical-product usage-status ascertainment device |
-
2017
- 2017-03-15 CN CN201710153073.8A patent/CN106861020B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN204500704U (en) * | 2015-03-12 | 2015-07-29 | 湖南埃普特医疗器械有限公司 | A kind of mapping micro-wire |
| CN105018082A (en) * | 2015-07-10 | 2015-11-04 | 上海纳米技术及应用国家工程研究中心有限公司 | Method for preparing carbon quantum dot labeled probe for silk fibroin extracted cell development |
| CN207137137U (en) * | 2017-03-15 | 2018-03-27 | 北京聚精瑞生医疗科技有限公司 | Fluorography, which moves under water, punctures seal wire |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106861020A (en) | 2017-06-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US10314952B2 (en) | Method and device for simultaneously documenting and treating tension pneumothorax and/or hemothorax | |
| US20170319825A1 (en) | Intravascular catheter assembly | |
| US8078261B2 (en) | Light-guided transluminal catheter | |
| KR102431113B1 (en) | Sheath for sealed access to a vessel | |
| JP4605159B2 (en) | Catheter having a catheter position confirming member and the catheter position confirming member having a color change indicator | |
| US20120303011A1 (en) | Catheters and Methods for Identification and Treatment of Bodily Passages | |
| KR20080011179A (en) | Vascular access | |
| US10085649B1 (en) | Methods and devices for localizing the blood mass of an intracerebral hematoma | |
| US20190350672A1 (en) | Method and device for enhanced transdermal visualization of medical devices | |
| US20180344184A1 (en) | Catheter for monitoring pressure for muscle compartment syndrome | |
| CN107361726A (en) | Photographing in vivo device and aid group | |
| CN107847718A (en) | Centre mark thing for dilating sacculus | |
| CN106861020B (en) | Fluorescence self-development diving puncture guide wire | |
| MX2019004586A (en) | Transseptal insertion device. | |
| KR20170059656A (en) | Indentification device of epidural space and Tuohy needle therof | |
| CN106901870B (en) | Colored silicone for implant safety | |
| ITMI20110796A1 (en) | REMOVABLE IMPLANTABLE MEDICAL DEVICE IN BLOOD VASES, PARTICULARLY IN THE THORACIC AORTA WITH ANEURISMA. | |
| CN207137137U (en) | Fluorography, which moves under water, punctures seal wire | |
| CN206463031U (en) | Filament-drawing probe | |
| KR102191708B1 (en) | Suture needle | |
| CA3018508C (en) | Cannula locator device | |
| CN203263512U (en) | Intracoronary foreign matter catching device | |
| CN212415793U (en) | Special conveying sheath for congenital heart disease plugging device and treatment assembly | |
| JP2015126885A (en) | Medical instrument emitting near infrared fluorescence and medical instrument position confirmation system | |
| CN217187424U (en) | Puncture drainage catheter external member |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |