CN106853002A

CN106853002A - It is a kind of to treat Chinese medicine composition of herpes zoster and preparation method thereof

Info

Publication number: CN106853002A
Application number: CN201510899063.XA
Authority: CN
Inventors: 韩丰河
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-12-09
Filing date: 2015-12-09
Publication date: 2017-06-16

Abstract

The present invention relates to a kind of Chinese medicine composition for treating herpes zoster Chinese medicine composition by the coptis, Ligusticum wallichii, Hedyotidis Diffusae, company, Radix Isatidis, Fructus Aurantii, Fructus meliae toosendan, safflower, raw cape jasmine, the root bark of tree peony, the radix paeoniae rubrathe, purslane, the root of large-flowered skullcap, plantain seed, peach kernel, folium isatidis, felwort, reticulate millettia, fuling peel, play both sides of the street and/or pharmaceutically acceptable carrier is made.The invention further relates to the preparation method of the Chinese medicine composition.Chinese traditional medicine composition of the present invention has the effect such as eliminating dampness and heat, promoting blood circulation and removing blood stasis, removing toxic substances analgesic, affected part pain, the tired powerless, poor appetite of whole body, feveret for causing for herpes zoster etc..

Description

It is a kind of to treat Chinese medicine composition of herpes zoster and preparation method thereof

Technical field

Chinese medicine composition of herpes zoster and preparation method thereof is treated the present invention relates to a kind of.

Background technology

Herpes zoster is the acute inflammation dermatoses caused by varicellazoster virus, and the traditional Chinese medical science is referred to as " skirt-roof fire Dragon ", " herpes zostor ".It is among the people to be commonly called as " She Dan ", " herpes zoster ".

The virus is by respiratory tract infection intrusive body, hiding to dorsal root ganglia or other site of pathological change In nerve cell.This virus can not usually fall ill, but due to the elderly and the people of weakness due to chronic disease, systemic resistance power declines, The inducements such as fatigue, flu are run into again, then easily send out this disease.Pathogenesis：Without immunity or low immunity after virus infection (majority is children to crowd）Primary infection can occur, that is, varicella occurs.Or viral subclinical infection, travel to skin sense through blood Feel nerve endings, root or trigeminal neuralgia after nerve pathway to spinal nerve are then propagate into the god of ganglia sensorialia nervi encephalici Through unit, when immunity of organisms declines (for example：Wound, flu, cancer, disease of immune system etc.), latent virus will Amount reproduction, makes neuromere inflammation, necrosis, causes Principle of Pain, while virus under nerve pathway along passing, to the innervation Region causes segmental bleb.Virus can also infect motor neuron, cause patient's myasthenia and motor paralysis, but rarely found. At the beginning of morbidity, be mainly shown as that whole body is tired powerless, lose the appetite, feveret, quickly site of pathological change feel scorching hot, jump and ache Bitterly.In the event of in chest or waist, it is heart disease or acute abdomen etc. that constant error is examined.

After obtaining herpes zoster 13 days, the skin of site of pathological change is the very big papule of mung bean grain size, tension force, water occur Blister, along Substance P, collection tufted arrangement, in ribbon.In the event of in chest, waist, more from the side of backbone diagonally forward under Side, few symmetrical morbidity.It is among the people to be passed：It is insecure if occur one to enclose bleb around waist is to be in peril of one's life.Suffer from This patient, the lighter per cluster can between be separated with normal skin, the person of being in a bad way can merge the zonal distribution of sheet, by clarifying after a few days Transparent blister is changed into muddy warts, partly can ulceration form erosion.Show as bleb, blood blister more the elderly, or even occur Necrosis.The lighter three weeks or so can dry up naturally, incrustation, and scar is not stayed after coming off；The severe one course of disease can be extended to more than one month. Having an intense pain often occurs in gerontal patient, influence sleep, if treatment is not in time, after skin damaged regression, still leaves pain, and the several months is not Can disappear completely.If herpes zoster appears in head, face, headache, the facial paralysis invaded Head And Face nerve and occur are vigilant. If cornea eye is invaded, or even also results in blindness.It is older, Low and with chronic disease persons such as tumours, The state of an illness can be even more serious.It is worth noting that, clinically also common to a kind of not holotype herpes zoster, patient is except conscious morbidity portion Outside position has an intense pain, blister occurs without or occurs seldom, it is easy to by mistaken diagnosis, should give great attention, in order to avoid affect treatment adversely, It was found that serious consequence.Herpes zoster can occur in facial trigeminal neuralgia sections, there is a nerve fibre, i.e. expression in the eyes in trigeminal neuralgia Through fiber, part of nerve fibers is distributed in the cornea of human eyeball, conjunctiva so that whole eyeball, the nerve fibre at the position is such as Fruit is subject to herpesvirus infection, and keratitis, ulcer of the cornea, conjunctivitis can occur, and patient can keep in dark place, shed tears, ocular pain, So that hypopsia, there is panophthalmitis and cause blindness in severe one.Motor fibre in herpesvirus infection to facial nerve When, facial paralysis will be produced, Ipsilateral eyes occur can not close, and Ipsilateral facial expression is stiff, and bicker slants tiltedly to strong, it is impossible to does and blows Pneumatic work etc..More by feelings will internal injury, with the passing of time stagnation of liver qi, the obstruction of the circulation of vital energy changes fire, the excessive skin of Liver Channel fiery poison for the generation of herpes zoster And send out；Or because of the dysfunction of the spleen in transport, endogenous dampness accumulates heat of wetting, retention of damp-heat in the interior, excessive skin and gives birth to；Or infection poison is evil, damp and hot fire Poison accumulates long-pending skin and forms.

The disease is divided into three types by the traditional Chinese medical science：

1. excessive heat type：Local skin damaged is scarlet, and tonic vesicle wall is scorching hot to twinge.Feel bitter taste in the mouth and dry throat, thirsty, unhappy easily irritability, food It is intended to not good.Red urine, stool is dry or not well.Red tongue body, thin lingual fur is yellow or yellow thick, the micro- number of wiry and rolling pulse.

2. wetness hyperactivity type：Skin color is thin, and flaccid vesicle wall, pain is slightly light, and mouth is not thirsty or is not intended to drink yearningly, do not feel like eating, Abdominal distention after meal, the common leukorrhea of female patient is more.Tongue nature is light fat, and tongue fur is white thick or white greasy, deep-slow pulse or cunning.

3. qi stagnation and blood stasis type：Local pain is more than after deflorescence.Dark tongue quality, tongue is white, small and wiry pulse.Traditional Chinese medical science Bian profits clearly It is damp and hot, promoting blood circulation and removing blood stasis, removing toxic substances analgesic decoction for the treatment this disease.

The content of the invention

It is an object of the invention to provide a kind of Chinese medicine composition for treating herpes zoster.The present invention also aims to provide A kind of preparation method of the Chinese medicine composition.

It is by having the invention provides a kind of Chinese medicine composition for treating herpes zoster to realize the purpose of the present invention Effect composition and/or pharmaceutically acceptable carrier are made, and described active ingredient is made up by weight of following raw materials according 's：Coptis 10-20 parts, river is curved 5-15 parts, oldenlandia diffusa 5-10 parts, capsule of weeping forsythia 15-25 parts, Radix Isatidis 15-25 parts, Fructus Aurantii 10- 20 parts, Fructus meliae toosendan 5-10 parts, safflower 10-15 parts, raw cape jasmine 5-10 parts, root bark of tree peony 20-30 parts, radix paeoniae rubrathe 15-25 parts, purslane 5- 20 parts, root of large-flowered skullcap 15-25 parts, plantain seed 10-15 parts, peach kernel 15-25 parts, folium isatidis 10-20 parts, felwort 5_10 parts, reticulate millettia 10-15 parts, obtain etc. skin 20_25 parts, play both sides of the street 10-20 parts.

Active ingredient is preferably made up by weight of following raw materials according：16 parts of the coptis, curved 10 parts of river, oldenlandia diffusa 8 Part, 21 parts of the capsule of weeping forsythia, 20 parts of Radix Isatidis, 16 parts of Fructus Aurantii, 8 parts of Fructus meliae toosendan, 13 parts of safflower, 8 parts of raw cape jasmine, 26 parts of the root bark of tree peony, the radix paeoniae rubrathe 21 Part, 16 parts of purslane, 21 parts of the root of large-flowered skullcap, 13 parts of plantain seed, 21 parts of peach kernel, 16 parts of folium isatidis, 8 parts of felwort, 13 parts of reticulate millettia, 23 parts of the skin such as obtain, play both sides of the street 16 parts.

Present invention also offers a kind of preparation method of the Chinese medicine composition, comprise the steps：

(1) coptis, the root bark of tree peony, reticulate millettia are secondary with 60% alcohol reflux, one hour every time, filter by several times, merging filtrate, depressurize dense Shorten the clear cream that relative density is 1. 15 (60 DEG C) into；

(2) Ligusticum wallichii, oldenlandia diffusa, the capsule of weeping forsythia, Radix Isatidis, Fructus Aurantii, Fructus meliae toosendan, safflower, raw cape jasmine, the radix paeoniae rubrathe, purslane, the root of large-flowered skullcap, Plantain seed, peach kernel, folium isatidis, felwort, fuling peel, play both sides of the street that it is secondary to add water to cook, 2 hours every time, filtration, merging filtrate, 48 hours are stood, supernatant is taken, the thick paste that relative density is 1. 20 (60 DEG C) is concentrated under reduced pressure into, above-mentioned clear cream is added, with medicine Acceptable carrier is made gel on.

Chinese traditional medicine composition of the present invention has the effect such as eliminating dampness and heat, promoting blood circulation and removing blood stasis, removing toxic substances analgesic, causes for herpes zoster Affected part pain, whole body are tired powerless, poor appetite, the disease such as feveret.

Specific embodiment

Following examples are used to illustrate the present invention, but are not limited to the scope of the present invention.

Embodiment：Chinese medicine composition gelata of the present invention:

(1) Fructus Aurantii 160g, coptis 160g, root bark of tree peony 260g, reticulate millettia 130g are secondary with 60% alcohol reflux, one hour every time, point Secondary filtration, merging filtrate is concentrated under reduced pressure into the clear cream that relative density is 1. 05 (60 DEG C)；

(2) Ligusticum wallichii 100g, oldenlandia diffusa 80g, capsule of weeping forsythia 210g, Radix Isatidis 200g, Fructus Aurantii 160g, Fructus meliae toosendan 80g, safflower 130g, raw cape jasmine 80g, radix paeoniae rubrathe 210g, purslane 160g, root of large-flowered skullcap 210g, plantain seed 130g, peach kernel 210g, folium isatidis 160g, Felwort 80g, fuling peel 230g, the 160g that plays both sides of the street add water to cook secondary, and 2 hours every time, filtration, merging filtrate stood 48 small When, supernatant is taken, the thick paste that relative density is 1. 05 (60 DEG C) is concentrated under reduced pressure into, above-mentioned clear cream is added, stir, it is standby With.Carbomer 30g mixes with Tween-80 4g and 500ml pure water, adds 4% oxygen sodium oxide molybdena 500ml, equal Uniform is stirred, by nipalgin Ester 2g is added after being dissolved in 150ml ethanol, is stirred.The addition stirring of cream liquid is obtained final product again.

Claims

1. a kind of Chinese medicine composition for treating herpes zoster, is made up of active ingredient and/or pharmaceutically acceptable carrier, its It is characterised by, described active ingredient is made up by weight of following raw materials according：Coptis 10-20 parts, Ligusticum wallichii 5-15 parts, Oldenlandia diffusa 5-10 parts, capsule of weeping forsythia 15-25 parts, Radix Isatidis 15-25 parts, Fructus Aurantii 10-20 parts, Fructus meliae toosendan 5_10 parts, safflower 10- 15 parts, raw cape jasmine 5-10 parts, root bark of tree peony 20-30 parts, radix paeoniae rubrathe 15-25 parts, purslane 5-20 parts, root of large-flowered skullcap 15-25 parts, plantain seed 10- 15 parts, peach kernel 15-25 parts, folium isatidis 10-20 parts, felwort 5-10 parts, reticulate millettia 10-15 parts, fuling peel 20-25 parts, Lu Lu It is logical 10-20 parts.

2. Chinese medicine composition according to claim 1, it is characterised in that described active ingredient is by weight by following raw materials according Amount part meter is made：16 parts of the coptis, 10 parts of Ligusticum wallichii, 8 parts of oldenlandia diffusa, 21 parts of the capsule of weeping forsythia, 20 parts of Radix Isatidis, 16 parts of Fructus Aurantii, river 8 parts of chinaberry, 13 parts of safflower, 8 parts of raw cape jasmine, 26 parts of the root bark of tree peony, 21 parts of the radix paeoniae rubrathe, 16 parts of purslane, 21 parts of the root of large-flowered skullcap, 13 parts of plantain seed, 21 parts of peach kernel, 16 parts of folium isatidis, 8 parts of felwort, 13 parts of reticulate millettia, 23 parts of the skin such as obtain, play both sides of the street 16 parts.

3. according to any described Chinese medicine compositions of claim 1-2, it is characterised in that the Chinese traditional medicine composition can be made into gel.