CN106829000A - The apparatus and its facial mask preparation method of a kind of sterile filling facial mask - Google Patents

The apparatus and its facial mask preparation method of a kind of sterile filling facial mask Download PDF

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Publication number
CN106829000A
CN106829000A CN201710069759.9A CN201710069759A CN106829000A CN 106829000 A CN106829000 A CN 106829000A CN 201710069759 A CN201710069759 A CN 201710069759A CN 106829000 A CN106829000 A CN 106829000A
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CN
China
Prior art keywords
facial mask
sterilization
steam
filling
bottle placer
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Granted
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CN201710069759.9A
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CN106829000B (en
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喻君
孙杨
李俊成
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Guangzhou's No Added Cosmetics Co Ltd
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Guangzhou's No Added Cosmetics Co Ltd
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Priority to CN201710069759.9A priority Critical patent/CN106829000B/en
Publication of CN106829000A publication Critical patent/CN106829000A/en
Priority to PCT/CN2017/099148 priority patent/WO2018145446A1/en
Priority to SG11201801259PA priority patent/SG11201801259PA/en
Priority to ZA2018/00673A priority patent/ZA201800673B/en
Priority to FR1851028A priority patent/FR3062571B1/en
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Publication of CN106829000B publication Critical patent/CN106829000B/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0212—Face masks
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/04—Methods of, or means for, filling the material into the containers or receptacles
    • B65B3/10—Methods of, or means for, filling the material into the containers or receptacles by application of pressure to material
    • B65B3/12—Methods of, or means for, filling the material into the containers or receptacles by application of pressure to material mechanically, e.g. by pistons or pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35—Ketones, e.g. benzophenone
    • A61K8/355—Quinones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4986—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with sulfur as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/673—Vitamin B group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/673—Vitamin B group
    • A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/676—Ascorbic acid, i.e. vitamin C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/678—Tocopherol, i.e. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/731—Cellulose; Quaternized cellulose derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/88—Polyamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B55/00—Preserving, protecting or purifying packages or package contents in association with packaging
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B55/00—Preserving, protecting or purifying packages or package contents in association with packaging
    • B65B55/02—Sterilising, e.g. of complete packages
    • B65B55/12—Sterilising contents prior to, or during, packaging
    • B65B55/14—Sterilising contents prior to, or during, packaging by heat
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B55/00—Preserving, protecting or purifying packages or package contents in association with packaging
    • B65B55/02—Sterilising, e.g. of complete packages
    • B65B55/12—Sterilising contents prior to, or during, packaging
    • B65B55/16—Sterilising contents prior to, or during, packaging by irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/30—Characterized by the absence of a particular group of ingredients

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Mechanical Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Toxicology (AREA)
  • Cosmetics (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)

Abstract

The invention belongs to cosmetic technical field, the apparatus and its facial mask preparation method of specifically related to a kind of sterile filling facial mask, the apparatus include high temperature drying case, autoclave sterilization tank, the transfer pipeline of high-temp steam sterilizing can be used, can high-temp steam sterilizing bottle placer and hundred grades of racking rooms.The equipment can well be sterilized to facial mask, and preservative need not be added in facial mask, can both ensure the aseptic of facial mask.

Description

The apparatus and its facial mask preparation method of a kind of sterile filling facial mask
Technical field
The invention belongs to cosmetic technical field, and in particular to a kind of apparatus of sterile filling facial mask and its facial mask Preparation method.
Background technology
In mask product, because water content is very more in facial mask, easily by microorganism pollution, so to sterilizing and anti-corrosion Ability has requirement higher., generally using there is preservative, preservative is for face pack prescription inhibitor effectiveness application conduct for existing facial mask Protect a product from microorganism pollution, rotten, the shelf life of extension product.But it is itself unwanted contributions for skin care, The excitant of skin can possibly even be increased and allergy etc. is caused；To ensure the security of product, in order to prevent consumer because using Caused possible infection by the product of microorganism pollution, if the amount of preservative addition is not enough, is likely to occur microorganism and fits Growing environment around answering, develops immunity to drugs, so as to cause anti-corrosion to fail.Preferable preservative should have spectrum activity, can be compared with It is fast make microorganism deactivated, formulation stable, long-term use safely, have no stimulation and sensitization.In general, it is most of anti- Rotten agent or to antibacterium effectively or to it is antimycotic effectively, it is impossible to while effective to both；At present on the market for Compositional antiseptic agent compared with It is many.Preservative is useless in itself to skin care, or even can increase excitant and sensitization of skin etc. on the contrary, such as produced by Phenoxyethanol Burning heat sensation, methylisothiazolinone (MIT) issuable allergy etc..Therefore existing cosmetics relevant laws and regulations requirement is also clear and definite Define the addition requirement of regulated substance (preservative).At present in mask product production, use traditional hot pressing and go out Bacterium process, this method has the drawback that can make the mounted facial mask in face cause facial mask bag deformed dilation, fracture phenomena.With The originally and naturally safe theory of Cosmetics in China consumption consciousness successive Regression, " zero addition " " zero burden ", " without anti-corrosion Agent " etc. is increasingly taken seriously and praises highly, and especially with facial mask fast sale in recent years, the development and application of sterilization technology is to changing Cosmetic safety and natural research and development field play more and more important effect
The content of the invention
For these reasons, applicant includes by obtaining a kind of new apparatus, the apparatus for many years：Including height Warm drying box, autoclave sterilization tank can use the transfer pipeline of high-temp steam sterilizing, can high-temp steam sterilizing bottle placer and hundred grades Racking room；The equipment can well be sterilized to facial mask, and preservative need not be added in facial mask, can both ensure facial mask It is aseptic.
What the present invention was achieved through the following technical solutions.
A kind of equipment of sterilization filling facial mask, including high temperature drying case, autoclave sterilization tank, can use high-temp steam sterilizing Transfer pipeline, can high-temp steam sterilizing bottle placer and hundred grades of racking rooms.
A kind of equipment of sterile filling facial mask, including high temperature drying case, autoclave sterilization tank, can use high-temperature steam The transfer pipeline of sterilizing, can high-temp steam sterilizing bottle placer and hundred grades of racking rooms, described high-temperature sterilization tank steamed using high temperature Vapour sterilizes, the device by the closed tank body of jacketed and agitating paddle, air cleaner, material-feeding port, peristaltic pump, temperature inductor with And control system composition；The Inner material conveying tubes route is with tank connected inlet valve, stainless steel delivery pipe, the steam inlet of sterilizing Valve, dead angle air bleeding valve, blowoff valve, blow-off pipe and the outlet valve composition being connected with bottle placer；It is described can sterilization filling machine by pushing up Portion's transparent protective shield with holes, high temperature resistant conveying flexible pipe, high temperature resistant gear pump, stainless steel filling head, ultraviolet lamp system, UV resistance lamp Outer cover and blowoff line are constituted；Described hundred grades of bottling departments by changing rooms, buffering between, Airshower chamber, buffering corridor, Full fresh air purifying Air-conditioning, high efficiency particulate air filter is constituted with, uviol lamp and differential pressure indicator；Facial mask packaging material high temperature drying box sterilization, the sterilizing of facial mask raw material Tank is sterilized, and bottle placer is transported to through transfer pipeline, and sterilized facial mask packaging material filling and sealing is used under hundred grades of environment.
Wherein facial mask packaging material is processed 2 hours in high temperature drying case with 90 DEG C, can just be used after detection is aseptic, facial mask bag Material transport process is sealed with aseptic sealed bag.
Wherein facial mask raw material sterilizing is completed, and filtrated air is conveyed by air cleaner, keeps sterilization tank malleation.
Wherein conveying management sterilizing and bottle placer are sterilized and carry out simultaneously, and high-temperature steam, steam warp are passed through by steam inlet valve Discharged by transfer pipeline, outlet valve, high temperature resistant conveying flexible pipe, high temperature resistant gear pump, stainless steel filling head, blowoff line；Conveying Pipeline will open dead angle air bleeding valve and ensure that sterilizing is thorough when sterilizing.
Wherein the sterile wind of bottle placer is exported directly over bottle placer, and sterile wind is directly entered via top protective cover with holes Inside bottle placer, bottle placer internal positive pressure is kept.
Wherein pouring process bottle placer inside ultraviolet lamp system is opened, and pouring process is carried out under uviol lamp protection.
Wherein sterilization process method is comprised the following steps：
The facial mask raw material that step (1) will be prepared is added in sterilization tank, closed sterilization tank, agitating paddle is opened, by each component Stir；
Step (2) steam generator provides high temperature and high pressure steam and is heated up to sterilization tank, stops when tank temperature rise is to 105 DEG C Heat up, then 105 DEG C of retaining surface film raw material temperature 15~30 minutes starts cooling, is cooled to 20-40 DEG C；
Sterilized to air cleaner with high-temperature steam while step (3) facial mask raw material sterilizes, air mistake is kept after sterilizing Filter is closed；
Step (4) provides compressed air with air compressor, is passed through in sterilization tank via air cleaner, keeps in tank just Pressure；
Step (5), to steam is passed through in conveying pipeline, sterilizes via steam inlet valve to feeding pipe and bottle placer, keeps logical Steam -40 minutes 20 minutes, then closed all pipe-line systems；
Step (6) is sterilized more than 20 minutes with uviol lamp to bottling department space, closes uviol lamp, is passed through sterile wind, is kept Bottling department malleation；
The ultraviolet lamp system of step (7) opening bottle placer, opening conveying pipeline inlet valve, outlet valve, feed liquid is via conveying Pipeline enters bottle placer, starts filling.
Wherein facial mask raw material is made up of following weight portion：Co-Q10 0.01-0.1, olive oil 5-10, lipoic acid 0.1- 0.5, niacinamide 0.1-0.5, beta glucan 0.1-0.5, vitamin B60.1-0.5, vitamin C 1.0-3.0, vitamin B2 0.1-0.5, dipotassium glycyrrhizinate 0.1-0.5, citric acid 0.1-0.5, vitamin E 0.5-2.0,1,2-PD 5.0-10.0,1, 3- butanediol 1.0-5.0, polyglutamic acid 3.0-5.0, hydroxyethyl cellulose 0.1-0.3, glycerine polymethacrylates/1,2- third Glycol/Gantrez AN-119 4.0-8.0, triethanolamine 0.1-0.5, sodium lactate 1.0-3.5, Sensiva SC50 0.1-0.3, plus Deionized water is to 100.
Wherein facial mask preparation method for raw material is：Co-Q10 is taken, is added in olive oil, shaken 30 minutes at 35 DEG C, made auxiliary Enzyme Q10 is substantially dissolved in standby in olive oil；Deionized water, 1,3-BDO, polyglutamic acid, hydroxyethyl cellulose and water are mixed Close, be heated to 85 DEG C, Co-Q10, middle olive oil are added after dissolving completely, the poly- methyl of triethanolamine, glycerine is added at 50 DEG C Acrylate/1,2-PD/Gantrez AN-119, sodium lactate, niacinamide, beta glucan, lipoic acid, dipotassium glycyrrhizinate is stirred Mix to being completely dissolved；Less than 45 DEG C add vitamin C, vitamin B6, citric acid, Phenoxyethanol, Sensiva SC50 etc. other Raw material, the facial mask raw material for being prepared.
The present invention compared with prior art, with advantages below and high-lighting effect：Changing facial mask raw material completely needs to add The present situation of adding preservative agent or preservative substance, complete preservative free preservative substance can be produced using system of the invention and technique Facial mask raw material, greatly improves the security of product, reduces to anti-corrosion class material sensitive crowd using limitation, thoroughly eliminates potential Use hidden danger.The present invention is to be sterilized to reach anti-corrosion purpose with pure physical means, does not have any chemistry, radiation residual in product, It is not damaged in sealing packaging material and filling rear closed product integral asepsis in theory, substantially prolongs the shelf-life of product In the case of the shelf-life be the several years.Condition easily reaches in normal cosmetics industrial enterprise needed for system of the invention and technique Into suitable large-scale production and application.
Brief description of the drawings
The aseptic filling systems principle schematic diagram. that Fig. 1 is provided for the present invention
In figure：1- autoclave sterilization tanks；2- transfer pipelines；3- can high-temp steam sterilizing bottle placer；4- chucks；5- is stirred Oar；6- air cleaners；7- material-feeding ports；8- peristaltic pumps；9- temperature inductors；10- inlet valves；11- steam inlet valves；12- is dead Angle air bleeding valve；13- blowoff valves；14- blow-off pipes；15- outlet valves；16- tops transparent protective shield with holes；17- high temperature resistant conveyings are soft Pipe；18- high temperature resistant gear pumps；19- stainless steel filling heads；20- ultraviolet lamp systems；21- UV resistance lamp outer covers；22- blowoff lines； 23- high efficiency particulate air filters；24- feed supplements bottle.
The sterile filling process flow diagram that Fig. 2 is provided for the present invention.
Specific embodiment
Technical scheme, but protection scope of the present invention not limited to this are illustrated with specific embodiment below.
Content described in this specification embodiment is only enumerating to the way of realization of inventive concept, protection of the invention Scope is not construed as being only limitted to the concrete form that embodiment is stated, protection scope of the present invention is also and in art technology Personnel according to present inventive concept it is conceivable that equivalent technologies mean.Although embodiment of the invention below is retouched State, but the invention is not limited in above-mentioned specific embodiments and applications field, following specific embodiments is only to show It is meaning property, directiveness, rather than restricted.One of ordinary skill in the art is under the enlightenment of this specification and is not taking off In the case of the scope protected from the claims in the present invention, the form of many kinds can also be made, these belong to the present invention The row of protection.
Concrete structure of the invention, principle and technical process are described further below in conjunction with the accompanying drawings.
Embodiment 1
Facial mask prescription is：Co-Q10 0.01kg, olive oil 5kg, lipoic acid 0.1kg, niacinamide 0.1kg, beta glucan 0.1kg, vitamin B6 0.1kg, vitamin C 1.0kg, vitamin B2 0.1kg, dipotassium glycyrrhizinate 0.1kg, citric acid 0.1kg, vitamin E 0.5kg, 1,2-PD 5.0kg, 1,3-BDO 1.0kg, polyglutamic acid 3.0kg, hydroxy ethyl fiber Plain 0.1kg, glycerine polymethacrylates/1,2-PD/Gantrez AN-119 4.0kg, triethanolamine 0.1kg, sodium lactate 1.0kg, Sensiva SC50 0.1kg, plus deionized water is to 100kg.
Facial mask preparation method for raw material is：Co-Q10 is taken, is added in olive oil, shaken 30 minutes at 35 DEG C, make coenzyme Q10 is substantially dissolved in standby in olive oil；Deionized water, 1,3-BDO, polyglutamic acid, hydroxyethyl cellulose are mixed, plus Heat is added in Co-Q10, olive oil to 85 DEG C, after dissolving completely, and triethanolamine, glycerine polymethylacrylic acid are added at 50 DEG C Ester/1,2-PD/Gantrez AN-119, sodium lactate, niacinamide, beta glucan, lipoic acid, dipotassium glycyrrhizinate, stirring is to complete CL；Less than 45 DEG C add vitamin C, vitamin B6, citric acid, other raw materials such as Sensiva SC50 are prepared Facial mask raw material.
Embodiment 2
Facial mask prescription is：Co-Q10 0.05kg, olive oil 7.5kg, lipoic acid 0.25kg, niacinamide 0.25kg, β-Portugal Glycan 0.25kg, vitamin B60.25kg, vitamin C 2kg, vitamin B20.25kg, dipotassium glycyrrhizinate 0.25kg, citric acid 0.25kg, vitamin E 1.5kg, 1,2-PD 7.5kg, 1,3-BDO 2.5kg, polyglutamic acid 4kg, hydroxyethyl cellulose 0.2kg, glycerine polymethacrylates/1,2-PD/Gantrez AN-119 6kg, triethanolamine 0.25kg, sodium lactate 2.5kg, Sensiva SC50 0.2kg, plus deionized water is to 100kg.
Facial mask preparation method for raw material is：Co-Q10 is taken, is added in olive oil, shaken 30 minutes at 35 DEG C, make coenzyme Q10 is substantially dissolved in standby in olive oil；Deionized water, 1,3-BDO, polyglutamic acid, hydroxyethyl cellulose are mixed, plus Heat is added in Co-Q10, olive oil to 85 DEG C, after dissolving completely, and triethanolamine, glycerine polymethylacrylic acid are added at 50 DEG C Ester/1,2-PD/Gantrez AN-119, sodium lactate, niacinamide, beta glucan, lipoic acid, dipotassium glycyrrhizinate, stirring is to complete CL；Less than 45 DEG C add vitamin C, vitamin B6, citric acid, other raw materials such as Sensiva SC50 are prepared Facial mask raw material.
Embodiment 3
Co-Q10 0.1kg, olive oil 10kg, lipoic acid 0.5kg, niacinamide 0.5kg, beta glucan 0.5kg, vitamin B60.5kg, vitamin C 3kg, vitamin B20.5kg, dipotassium glycyrrhizinate 0.5kg, citric acid 0.5kg, vitamin E 2kg, 1, 2- propane diols 10kg, 1,3-BDO 5kg, polyglutamic acid 5kg, hydroxyethyl cellulose 0.3kg, glycerine polymethacrylates/ 1,2-PD/Gantrez AN-119 8kg, triethanolamine 0.5kg, sodium lactate 3.5kg, Sensiva SC50 0.3kg, plus go from Sub- water is to 100kg.
Facial mask preparation method for raw material is：Co-Q10 is taken, is added in olive oil, shaken 30 minutes at 35 DEG C, make coenzyme Q10 is substantially dissolved in standby in olive oil；Deionized water, 1,3-BDO, polyglutamic acid, hydroxyethyl cellulose are mixed, plus Heat adds Co-Q10, olive oil total to 85 DEG C, after dissolving completely, and triethanolamine, glycerine polymethylacrylic acid are added at 50 DEG C Ester/1,2-PD/Gantrez AN-119, sodium lactate, niacinamide, beta glucan, lipoic acid, dipotassium glycyrrhizinate, stirring is to complete CL；Less than 45 DEG C add vitamin C, vitamin B6, citric acid, other raw materials such as Sensiva SC50 are prepared Facial mask raw material.
The aseptic filling systems principle schematic diagram. that Fig. 1 is provided for the present invention, the system includes packaging material disinfection system, face Film raw material is prepared and disinfection system, facial mask feedstock transportation and aseptic filling systems, i.e., mainly by high temperature drying case, HTHP goes out Bacterium tank (1), can use the transfer pipeline (2) of high-temp steam sterilizing, can high-temp steam sterilizing bottle placer (3) and hundred grades of racking rooms, Described high-temperature sterilization tank uses high-temp steam sterilizing, and the device is by jacketed (4) and closed tank body, the air of agitating paddle (5) Filter (6), material-feeding port (7), peristaltic pump (8) and temperature inductor (9) composition；The facial mask feedstock transportation pipeline (2) by With tank connected inlet valve (10), steam inlet valve (11), dead angle air bleeding valve (12), blowoff valve (13), the blow-off pipe (14) of sterilizing And outlet valve (15) composition being connected with bottle placer；It is described can sterilization filling machine by top transparent protective shield with holes (16), resistance to High temperature conveying flexible pipe (17), high temperature resistant gear pump (18), outside stainless steel filling head (19), ultraviolet lamp system (20), UV resistance lamp Cover (21) and blowoff line (22) composition；Described hundred grades of bottling departments by changing rooms, buffering between, Airshower chamber, buffering corridor, completely newly Wind clean air conditioner, high efficiency particulate air filter (23), uviol lamp and differential pressure indicator composition.Facial mask raw material packaging material high temperature drying box sterilization, face Film raw material is sterilized with sterilization tank, and bottle placer is transported to through transfer pipeline, and sterilized facial mask raw material bag is used under hundred grades of environment Material filling and sealing.
The sterile filling process flow diagram that Fig. 2 is provided for the present invention, the filling process mainly includes packaging material sterilizing, facial mask The process procedure such as raw material preparation, the sterilizing of facial mask raw material, feed supplement, transfer pipeline sterilizing, bottle placer sterilizing, bottling department sterilizing, filling, It specifically includes following steps：
Facial mask raw material packaging material is processed 2 hours in high temperature drying case with 90 DEG C, can just be used after detection is aseptic, and facial mask is former Material packaging material transport process is sealed with aseptic sealed bag；
By in embodiment 1 or embodiment 2 or the facial mask raw material of embodiment 3 addition sterilization tank (1), closed sterilization tank, opening is stirred Oar (5) is mixed, each component is stirred；
High temperature and high pressure steam is provided with steam generator to be heated up to sterilization tank, stop heating up when tank temperature rise is to 105 DEG C, protect Hold facial mask material temperature 105 DEG C 15~30 minutes, then start cooling, be cooled to less than 40 DEG C, qualified side is checked in sampling detection Next process can be carried out；
Sterilized -30 minutes 15 minutes to air cleaner with high-temperature steam while facial mask raw material sterilizes, kept after sterilizing Air cleaner is closed；
Such as need feed supplement that sterilized feed supplement bottle (24) is connected into sterilization tank (1) by material-feeding port (7), will with peristaltic pump (8) Feed supplement pumps into sterilization tank, and stirring is well mixed for -40 minutes 20 minutes with tank facial mask material liquid；
Compressed air is provided with air compressor, is passed through in sterilization tank via air cleaner (6), keep pressure inside the tank to exist 0.05MPa~0.1MPa (gauge pressure)；
Via steam inlet valve (11) to steam is passed through in conveying pipeline (2), to feeding pipe (2) and bottle placer sterilizing (3), Keep logical steam more than 20 minutes, then closed all pipe-line systems；
Sterilized more than 20 minutes to bottling department space with uviol lamp, close uviol lamp, be passed through sterile wind, keeping bottling department just Pressure, with buffering corridor pressure difference in more than 8Pa；
Open bottle placer ultraviolet lamp system (20), open conveying pipeline inlet valve (10), outlet valve (11), feed liquid via Conveying pipeline (2) enters bottle placer (3), and beginning is filling, obtains facial mask.
Comparative example：Facial mask prescription is：Co-Q10 0.05kg, olive oil 7.5kg, lipoic acid 0.25kg, niacinamide 0.25kg, beta glucan 0.25kg, vitamin B60.25kg, vitamin C 2kg, vitamin B20.25kg, dipotassium glycyrrhizinate 0.25kg, citric acid 0.25kg, vitamin E 1.5kg, 1,2-PD 7.5kg, 1,3-BDO 2.5kg, polyglutamic acid 4kg, hydroxyethyl cellulose 0.2kg, glycerine polymethacrylates/1,2-PD/Gantrez AN-119 6kg, triethanolamine 0.25kg, sodium lactate 2.5kg, Phenoxyethanol 0.2g, Sensiva SC50 0.2kg, plus deionized water is to 100kg.
Facial mask preparation method for raw material is：Co-Q10 is taken, is added in olive oil, shaken 30 minutes at 35 DEG C, make coenzyme Q10 is substantially dissolved in standby in olive oil；Deionized water, 1,3-BDO, polyglutamic acid, hydroxyethyl cellulose are mixed, plus Heat to 85 DEG C, dissolving completely after add Co-Q10 olive oil, added at 50 DEG C triethanolamine, glycerine polymethacrylates/ 1,2-PD/Gantrez AN-119, sodium lactate, niacinamide, beta glucan, lipoic acid, dipotassium glycyrrhizinate, stirring to completely it is molten Solution；Less than 45 DEG C add vitamin C, vitamin B6, other are former for citric acid, Phenoxyethanol (preservative), Sensiva SC50 etc. Material, lets cool, 0.22 μm of filtering, pours into infused film cloth in the container equipped with facial present situation bonded fabric, is packed after infiltration.
The different sterilizing methods mask product contamination rate experimental datas of table 1 are as follows
Conclusion (of pressure testing)：It can be seen from upper table, with the mask product contamination rate of present invention process production below 0.5%, tool The value of standby large-scale production.

Claims (10)

1. a kind of equipment of sterilization filling facial mask, it is characterised in that：Including high temperature drying case, autoclave sterilization tank can use height The transfer pipeline of warm steam sterilizing, can high-temp steam sterilizing bottle placer and hundred grades of racking rooms.
2. a kind of equipment of sterile filling facial mask according to claim 1, it is characterised in that：Including high temperature drying case, high temperature Autoclaving tank, can use the transfer pipeline of high-temp steam sterilizing, can high-temp steam sterilizing bottle placer and hundred grades of racking rooms, it is described High-temperature sterilization tank use high-temp steam sterilizing, the device by jacketed and agitating paddle closed tank body, air cleaner, feed supplement Mouth, peristaltic pump, temperature inductor and control system composition；Inner material conveying tubes route with the tank connected inlet valve that sterilizes, Stainless steel delivery pipe, steam inlet valve, dead angle air bleeding valve, blowoff valve, blow-off pipe and the outlet valve composition being connected with bottle placer； It is described can sterilization filling machine by top transparent protective shield with holes, high temperature resistant conveying flexible pipe, high temperature resistant gear pump, stainless steel is filling Head, ultraviolet lamp system, UV resistance lamp outer cover and blowoff line composition；Described hundred grades of bottling departments by changing rooms, buffering between, wind drench Room, buffering corridor, Full fresh air purifying air-conditioning, high efficiency particulate air filter are constituted with, uviol lamp and differential pressure indicator；Facial mask packaging material high temperature drying Box sterilization, facial mask raw material is sterilized with sterilization tank, and bottle placer is transported to through transfer pipeline, and sterilized face is used under hundred grades of environment Film packaging material filling and sealing.
3. the equipment of a kind of sterilization filling facial mask according to claim 2, it is characterised in that：Facial mask packaging material is in high temperature drying Processed 2 hours with 90 DEG C in case, can just be used after detection is aseptic, facial mask packaging material transport process is sealed with aseptic sealed bag.
4. the equipment of a kind of sterilization filling facial mask according to claim 2, it is characterised in that：The sterilizing of facial mask raw material is completed, Filtrated air is conveyed by air cleaner, sterilization tank malleation is kept.
5. the equipment of a kind of sterilization filling facial mask according to claim 2, it is characterised in that：Conveying management sterilizes and filling Machine sterilizing is carried out simultaneously, and high-temperature steam is passed through by steam inlet valve, and steam is soft via transfer pipeline, outlet valve, high temperature resistant conveying Pipe, the discharge of high temperature resistant gear pump, stainless steel filling head, blowoff line；Conveying pipeline will open dead angle air bleeding valve when sterilizing Ensure that sterilizing is thorough.
6. the equipment of a kind of sterilization filling facial mask according to claim 2, it is characterised in that：The sterile wind outlet of bottle placer Directly over bottle placer, sterile wind is directly entered inside bottle placer via top protective cover with holes, keeps bottle placer internal positive pressure.
7. the equipment of a kind of sterilization filling facial mask according to claim 2, it is characterised in that：Inside pouring process bottle placer Ultraviolet lamp system is opened, and pouring process is carried out under uviol lamp protection.
8. the equipment of a kind of sterilization filling facial mask according to claim 2, it is characterised in that sterilization process method include with Lower step：
The facial mask raw material that step (1) will be prepared is added in sterilization tank, closed sterilization tank, opens agitating paddle, and each component is stirred Uniformly；
Step (2) steam generator provides high temperature and high pressure steam and is heated up to sterilization tank, stops rising when tank temperature rise is to 105 DEG C Then temperature, 105 DEG C of retaining surface film raw material temperature 15~30 minutes starts cooling, is cooled to 20-40 DEG C；
Sterilized to air cleaner with high-temperature steam while step (3) facial mask raw material sterilizes, air cleaner is kept after sterilizing It is closed；
Step (4) provides compressed air with air compressor, is passed through in sterilization tank via air cleaner, keeps malleation in tank；
Step (5), to steam is passed through in conveying pipeline, sterilizes via steam inlet valve to feeding pipe and bottle placer, keeps logical steam - 40 minutes 20 minutes, then closed all pipe-line systems；
Step (6) is sterilized more than 20 minutes with uviol lamp to bottling department space, closes uviol lamp, is passed through sterile wind, is kept filling Between malleation；
The ultraviolet lamp system of step (7) opening bottle placer, opening conveying pipeline inlet valve, outlet valve, feed liquid is via conveying pipeline Into bottle placer, start filling.
9. a kind of equipment of sterilization filling facial mask according to claim 8, wherein facial mask raw material is made up of following weight portion： Co-Q10 0.01-0.1, olive oil 5-10, lipoic acid 0.1-0.5, niacinamide 0.1-0.5, beta glucan 0.1-0.5, dimension life Plain B60.1-0.5, vitamin C 1.0-3.0, vitamin B20.1-0.5, dipotassium glycyrrhizinate 0.1-0.5, citric acid 0.1-0.5, Vitamin E 0.5-2.0,1,2-PD 5.0-10.0,1,3-BDO 1.0-5.0, polyglutamic acid 3.0-5.0, ethoxy are fine Dimension element 0.1-0.3, glycerine polymethacrylates/1,2-PD/Gantrez AN-119 4.0-8.0, triethanolamine 0.1- 0.5, sodium lactate 1.0-3.5, Sensiva SC50 0.1-0.3, plus deionized water is to 100.
10. the equipment of a kind of sterilization filling facial mask according to claim 9, wherein facial mask preparation method for raw material is：Take auxiliary Enzyme Q10, in adding olive oil, shakes 30 minutes at 35 DEG C, is substantially dissolved in Co-Q10 standby in olive oil；To go from Sub- water, 1,3-BDO, polyglutamic acid, hydroxyethyl cellulose and water mixing is heated to 85 DEG C, and coenzyme is added after dissolving completely Q10, middle olive oil, triethanolamine, glycerine polymethacrylates/1,2-PD/Gantrez AN-119 are added at 50 DEG C, Sodium lactate, niacinamide, beta glucan, lipoic acid, dipotassium glycyrrhizinate, stirring is to being completely dissolved；Less than 45 DEG C add vitamin C, Other raw materials such as vitamin B6, citric acid, Phenoxyethanol, Sensiva SC50, the facial mask raw material for being prepared.
CN201710069759.9A 2017-02-08 2017-02-08 The equipment and its sterilization filling method of sterilization filling facial mask Active CN106829000B (en)

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CN201710069759.9A CN106829000B (en) 2017-02-08 2017-02-08 The equipment and its sterilization filling method of sterilization filling facial mask
PCT/CN2017/099148 WO2018145446A1 (en) 2017-02-08 2017-08-25 Aseptic facial mask filling device and mask preparation method therefor
SG11201801259PA SG11201801259PA (en) 2017-02-08 2017-08-25 Facial mask aseptic-filling apparatus and Facial Mask Preparation Method Thereof
ZA2018/00673A ZA201800673B (en) 2017-02-08 2018-01-31 Facial mask aseptic-filling apparatus and facial mask preparation method thereof
FR1851028A FR3062571B1 (en) 2017-02-08 2018-02-07 ASEPTIC FILLING APPARATUS FOR A FACE MASK AND METHOD FOR PREPARING THE FACE MASK

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CN108144373A (en) * 2017-12-19 2018-06-12 新乡华青药业有限公司 The aseptic delivery system of sterile ophthalmic ointment agent material
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CN108578255A (en) * 2018-04-28 2018-09-28 苏州大学 A kind of production equipment of canthus patch
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CN111067804A (en) * 2019-12-29 2020-04-28 广州无添加主义化妆品有限公司 Preparation method of mask without preservative and preservative substitute
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CN107830391A (en) * 2017-11-09 2018-03-23 河南道骐汽车科技有限公司 A kind of lubricating oil filling apparatus with agitating function
CN108144373A (en) * 2017-12-19 2018-06-12 新乡华青药业有限公司 The aseptic delivery system of sterile ophthalmic ointment agent material
CN108144373B (en) * 2017-12-19 2020-12-11 新乡华青药业有限公司 Sterile transfer system for sterile ophthalmic ointment materials
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CN108578255A (en) * 2018-04-28 2018-09-28 苏州大学 A kind of production equipment of canthus patch
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CN111067804A (en) * 2019-12-29 2020-04-28 广州无添加主义化妆品有限公司 Preparation method of mask without preservative and preservative substitute
CN112870392A (en) * 2021-01-18 2021-06-01 盐城依慕生物科技有限公司 Preparation process of liquorice whitening and skin moistening cream
CN115193281A (en) * 2022-06-14 2022-10-18 广州汉方医学生物科技有限公司 Emulsification apparatus and emulsification method

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FR3062571B1 (en) 2023-03-10
FR3062571A1 (en) 2018-08-10

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