CN106822535A - A kind of Chinese medicine preparation for improving sow fertility and preparation method and application - Google Patents

A kind of Chinese medicine preparation for improving sow fertility and preparation method and application Download PDF

Info

Publication number
CN106822535A
CN106822535A CN201710139877.2A CN201710139877A CN106822535A CN 106822535 A CN106822535 A CN 106822535A CN 201710139877 A CN201710139877 A CN 201710139877A CN 106822535 A CN106822535 A CN 106822535A
Authority
CN
China
Prior art keywords
chinese
chinese medicine
preparation
sow
fruit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710139877.2A
Other languages
Chinese (zh)
Inventor
乔家运
李海花
朱琪
李玉鹏
王文杰
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tianjin Institute of Animal Husbandry and Veterinary Science
Original Assignee
Tianjin Institute of Animal Husbandry and Veterinary Science
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tianjin Institute of Animal Husbandry and Veterinary Science filed Critical Tianjin Institute of Animal Husbandry and Veterinary Science
Priority to CN201710139877.2A priority Critical patent/CN106822535A/en
Publication of CN106822535A publication Critical patent/CN106822535A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296Epimedium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/344Codonopsis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/39Convolvulaceae (Morning-glory family), e.g. bindweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/43Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/533Leonurus (motherwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/638Ligustrum, e.g. Chinese privet
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/64Orobanchaceae (Broom-rape family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of Chinese medicine preparation for improving sow fertility and preparation method and application.It is made up of fruit of Chinese wolfberry 20g, fruit of glossy privet 30g, Semen Cuscutae 30g, motherwort 30g, Radix Codonopsis 30g, bighead atractylodes rhizome 25g, Chinese yam 25g, barrenwort 30g, saline cistanche 20g, cloves 15g.The present invention further discloses the application that this Chinese medicine preparation produces healthy and strong son's aspect such as number and nascent nest counterpoise in raising litter size, the number of live births, nest.Result shows:By adding voluminous three sub- balls in sow material, the effect of sow fertility is improved to reach.

Description

A kind of Chinese medicine preparation for improving sow fertility and preparation method and application
Technical field
The invention belongs to farm animals nutrition technique research field, it is related to a kind of Chinese medicine system for improving sow fertility Preparation Method.
Background technology
Chinese medicine preparation has presented its advantage as additive for farm animal feed, and this will be the hair of animal health medicine from now on Exhibition direction, especially caused by the antibiotic in the increasingly serious present situation of medicament residue, drug resistance problems, Chinese medicine preparation is used as anti- The research and development of raw element substitute by people's extensive concern and research, has broad application prospects.
In recent years, because the breeding of the high intensity such as sow sequence breeding, gestation, lactation is produced, easily cause in its reproduction Secretion is disorderly and influence the fertility of sow.The fertility common manifestation of existing majority plant sow is Oestrus rate Low, rate of embryonic death is high, farrowing pig is few, strong son's rate is low, and the low phenomenon of culture benefit seriously governs the development of pig industry.
Chinese medicine preparation is general smaller without the resistance to the action of a drug or the resistance to the action of a drug, many to animal effect with raising with regulating yin and yang as principle Be immunized, build up health based on.Due to these advantages, increasing Chinese medicine preparation is applied to scale pig farm at present, female to improving Growth performance, reproductive performance, reinforcement immunity of organisms of pig etc. generate huge social benefit and warp with certain effect Ji benefit.
This research takes voluminous three sub- balls by the Suprapubic arch sling to pregnancy 75-84d, improves sow number born per litter, nest Equal number born alive, nest produce strong son's number and nascent nest counterpoise, so as to improve sow reproductive performance.
The content of the invention
A kind of Chinese medicine preparation for improving sow fertility(Voluminous three sub- balls), it is characterised in that it is by following weight Raw material is constituted:
Fruit of Chinese wolfberry 20-30g, fruit of glossy privet 20-35g, Semen Cuscutae 25-35g, motherwort 20-40g, Radix Codonopsis 25-35g, the bighead atractylodes rhizome 20-40g, Chinese yam 20-50g, barrenwort 25-35g, saline cistanche 20-30g, cloves 15-20g.
The currently preferred Chinese medicine preparation for improving sow fertility(Voluminous three sub- balls), it is characterised in that it is under State the raw material composition of weight:
It is fruit of Chinese wolfberry 20g, fruit of glossy privet 30g, Semen Cuscutae 30g, motherwort 30g, Radix Codonopsis 30g, bighead atractylodes rhizome 25g, Chinese yam 25g, excessive Sheep leaves of pulse plants 30g, saline cistanche 20g, cloves 15g.
The present invention further discloses the preparation method of the Chinese medicine preparation for improving sow fertility:
(1)The preparation method of honeyed bolus:
Chinese medicine was crushed into 300 mesh sieves by various broken technologies of medicinal material low-temperature submicron powder standby;Then by plurality of Chinese Ultramicro-powder The spherical oral solid preparation that end mixes and be made with the jujube flower honey through refining;What the described jujube flower honey refined referred to It is:Refined concentration pan is evaporated under reduced pressure, tender honey elder generation high-temperature heating, then slow fire persistently refined, made temperature up to 110~116 DEG C, There is the glossiness foam of light red, the viscosity picked up with hand is relatively strong, but without white silk, moisture is in 10-13%(w/w), impurity is filtered, Density is 1.4-1.5 at 15 DEG C;
(2)Close medicine pelletization:
Prescription Chinese herbal ultra-fine powder is well mixed, refined honey is equably integrated with medicinal powder in mixer first, honey is added while hot, It is fully and even, make its it is inside and outside all moisten, color and luster is consistent, neither too hard, nor too soft, can random kneading model, by bolus using ball-type press mold Machine is made spheroidal, gradually general in spherical mold to be made prescribed level, the pill of ball weight, is finally obtained final product using freeze-drying;
Quality inspection packaging honeyed bolus shall be rounded up uniformly, color and luster unanimously, especially should be fine and smooth, neither too hard, nor too soft.Water content control is packed in 10-12% Wrapped using the ball one of paraffin paper one, 15 balls fill a polyethylene plastic bag vacuum packaging.
Chinese medicine preparation the present invention further discloses raising sow fertility is for adjusting number born of sow and son The nascent nest counterpoise of pig, so that the application in terms of improving sow reproductive performance.Particularly:Farrowing rate, produce son's rate living, strong son's rate and just Raw litter weight.Result of the test shows:The farrowing rate of in-pig, strong son can be significantly improved to in-pig three sub- balls of fecund for oral administration Rate and the nascent nest counterpoise of piglet.
The present invention to adjust sow reproductive performance as principle, by improving sow production performance, so as to increase economic efficiency.
With the fruit of Chinese wolfberry, the fruit of glossy privet, Semen Cuscutae as main ingredient in side in formula of the invention, it is aided with motherwort, Radix Codonopsis and excessive sheep Leaves of pulse plants etc., wherein three sub- consumptions are not to be exceeded 30g respectively.
According to the various Chinese medicine physicochemical properties and active ingredient in this formula, the preparation technology to traditional Chinese powder medicine does the present invention System optimization, at utmost playing its drug action.We have mainly investigated following condition in development process:
1st, refined honey pelletization technology:
Refined concentration pan is evaporated under reduced pressure, tender honey elder generation high-temperature heating, then slow fire persistently refined, made temperature up to 110-116 DEG C, There is the glossiness foam of light red, relatively by force, but without white silk, now water content should lose water to the viscosity picked up with hand in 15-20% Divide about 10-13%, filter impurity, density is 1.4-1.5 at 15 degree after cooling.
Prescription Chinese herbal ultra-fine powder is well mixed, refined honey is equably integrated with medicinal powder in mixer first, now refined honey Temperature should be 65-70 DEG C.Using Freeze Drying Technique can more preferable curable type, and keep drug effect.
2nd, pack:Packaging uses built-in paraffin paper, external application plastic-aluminum vacuum valve bag.Moisture absorption, hardening are preferably prevented, are changed colour, Decompose, so as to guaranteed quality and take effect.
The pharmacological action of the Chinese medicine used in the present invention is as follows:
The fruit of Chinese wolfberry
Process:Raw fruit of Chinese wolfberry active compound is sieved with ommatidium, dust is weeded out and is picked the base of a fruit and thin stalk, dried and obtain final product.
Pharmacology:Nourishing liver and kidney benefiting shrewd head.
The fruit of glossy privet
Process:Crude drug is taken, impurity and stalk leaf, cleaning, drying is removed.
Pharmacology:With nourshing kidney benefit liver, the function of crow palpus improving eyesight.
Semen Cuscutae
Process:Net Semen Cuscutae is taken, is put in frying container, heated with slow fire, fried to slightly yellow, there is cracker, taking-up dries in the air cool.
Pharmacology:With tonifying kidney and nourishing liver, astringent sperm contracting urine, improving eyesight, antidiarrheal, antiabortive function.
Motherwort
Process:Impurity is removed, it is rapid to clean, run through, segment, dry.
Pharmacology:There are promoting blood circulation for regulating menstruation, the effect of removing blood stasis for promoting tissue regeneration
Radix Codonopsis
Process:Crude drug is taken, except removing LU, is cleaned, run through, cut sheet, dried.
Pharmacology:Tool tonifying middle-Jiao and Qi, strengthening spleen and tonifying lung effect.
The bighead atractylodes rhizome
Process:Crude drug is taken, impurity is removed, size is separated, run through with water, cuts sheet, is dried.Weed out chip.
Pharmacology:With strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, antiabortive function.
Chinese yam
Process:Crude drug is taken, impurity is removed, size is separate, cleaned, run through, cut sheet, dried, weed out chip.
Pharmacology:With engender liquid and benefic lung, tonifying spleen nourishing the stomach, the function of the puckery essence of kidney tonifying.
Barrenwort
Process:Crude drug is taken, impurity is removed, blade is won, clear water is sprayed, slightly moistened, chopping, dried.
Pharmacology:With kidney-replenishing, strengthening the bones and muscles, wind-damp dispelling function
Saline cistanche
Process:Crude drug is taken, impurity is removed, size is separated, slightly soaked, runs through, and cuts sheet, is dried.
Pharmacology:Tool kidney-replenishing, benefiting essence-blood, the function of relaxing bowel.
Cloves
Process:Net system removes impurity, weeds out grey bits
Pharmacology:Middle benefit gas drop is inverse;Warming kidney and enhancing yang.
Refined honey
Process:Pure honey is taken, is tempered with slow fire, filter skimming.
Pharmacology:Bowl spares, moisturizes, analgesic, removing toxic substances.
More detailed description of the present invention is as follows:
1 materials and methods
1.1 feed addictive prescriptions
Title:Piglet three sub- balls of fecund
Formula:Fruit of Chinese wolfberry 20g, fruit of glossy privet 30g, Semen Cuscutae 30g, motherwort 30g, Radix Codonopsis 30g, bighead atractylodes rhizome 25g, Chinese yam 25g, barrenwort 30g, saline cistanche 20g, cloves 15g.
Indication:Nourishing liver and kidney, air making-up and spleen enlivening is antiabortive supporing yang.We have obvious therapeutic effect to sow infertility, also The breeding potential of sow can be promoted.
Specification usage and dosage:Per ball 9g.For oral administration, once a day, a 3-5 ball five days is a course for the treatment of to sow consumption.
When using, above-mentioned sow three sub- balls of fecund are taken by prescribed dose to sow.
Experiment uses corn-soybean meal diet, with reference to NRC(1998)Swine rearing standard preparation piglet cradling material.Experiment day The composition of grain is as follows:
Corn 64.00, dregs of beans 15, wheat bran 14, fish meal 2, bone meal 0.5, salt 0.5, premix 4.
Digestible energy(MJ/kg):12.13rd, thick protein(%):14.59th, lysine(%):0.91st, calcium(%):1.12nd, total phosphorus (%):0.65.
Note:Vitamin, mineral trace element, amino acid etc. necessary to body are included in premix.
1.2 experimental designs
The health weight tire of experiment selection 3-4 tire pregnancies 75-84d is through producing(Du × long × big)Sow 20, and its these sow institutes Raw piglet, two treatment, blank control group are divided into by completely random:Feeding Basic drawing;Test group:Feeding Basic drawing + innerwear Chinese medicine preparation(Each 3-5 balls).Each 10 repetition for the treatment of, each repeats 1 piglet, tests antenatal in in-pig 30d starts, to Farrowing.
1.3 feedings and managements
Pig enclosed grazing during experiment, experiment sow uses identical feeding and management and environmental condition, and dry mash feeding is free Feeding and drinking-water, are immunized during experiment by pig farm normal procedure, carried out disinfection by pig farm feeding and management code and cleaning is defended The work such as raw.Period observes sow health status, recording medicine and extremely naughty situation.
1.4 Testing index and method
1.4.1 sow reproductive performance index
In whole process of the test, every nest nest product subnumber, the number of live birth, nest are recorded respectively and produces strong son's number and weigth at birth.
1.5 statistical analyses
The data of statistical analysis each group, using one-way ANOVA(IBM SPSS Statistics 20.0)Variance test is analyzed. Data are represented with " means standard deviation " in text, probabilityP <Significant difference, probability are thought when 0.05P <Difference is thought when 0.01 It is extremely notable.
2 results and analysis
2.1 sow fertilities
As shown in Table 1, compared with control group, innerwear Chinese medicine preparation group litter size, the number of live births, nest produce strong son Several and nascent nest counterpoise is notable(P < 0.05)Improve, produce son's rate living with strong son's rate is produced and be respectively increased 4.34% and 4.63%.Cause This, gives sow heavy in pig three sub- balls of fecund for oral administration, can effective conditioning engine body, allow the fetus more nutrition of acquisition, meet tire The fast-growth of youngster, improves nascent nest counterpoise, nest son's rate living and nest is good for son's rate, so as to improve the fertility of sow.
Influence of the Chinese medicine preparation of table 1 to sow fertility
Note:Colleague's shoulder mark in table, lowercase is different, represents that control group is notable with test group result difference(p<0.05);Capitalization Alphabetical different expression control groups are extremely notable with test group result difference(p<0.01).
The present invention gives sow heavy in pig innerwear Chinese medicine preparation(Voluminous three sub- balls), to Chinese medicine preparation(Voluminous three sub- balls)Enter Safety experiment is gone, its method is as follows:
1 step:
(1)Material and method:Du × the length of selection gestation 75-84d × big piglet 6, clinical health, development are normal, experimental period 30 days, poisoning manifestations and death condition are observed in experimental period at any time.
(2)The sow feed raw material composition of feeding:
Corn 63.0, dregs of beans 16, wheat bran 14, fish meal 2, bone meal 0.5, salt 0.5, premix 4.
Note:Vitamin, mineral trace element, amino acid etc. necessary to body are included in premix.
Taken once by interior daily, one time the dosage of 5 balls is used for sow heavy in pig.
2 results:In-pig three sub- balls of fecund for oral administration are given, continuous feeding 30 days has no obvious intoxicating phenomenon, observation period It is interior without death, each main organs of cut open inspection show no obvious abnormalities.
3 conclusions:The voluminous three sub- balls of in-pig 3-5 balls for oral administration, feeding effect safety.
The positive effect that the Chinese medicine preparation for improving sow fertility disclosed by the invention has compared with prior art It is really:Significantly(P < 0.05)Litter size, the number of live births, the nest that improve sow produce strong son's number and come into being Nest counterpoise.
Specific embodiment
The present invention is described below by specific embodiment.Unless stated otherwise, technological means used in the present invention It is method known in those skilled in the art.In addition, embodiment is interpreted as illustrative, it is not intended to limit the present invention Scope, the spirit and scope of the invention are limited only by the claims that follow.To those skilled in the art, without departing substantially from this On the premise of invention spirit and scope, the various changes that are carried out to the material component and consumption in these embodiments or change Belong to protection scope of the present invention.Raw materials used and reagent of the invention is commercially available.
Embodiment 1
Voluminous three sub- balls are made up of the raw material of following weight:
It is fruit of Chinese wolfberry 20g, fruit of glossy privet 30g, Semen Cuscutae 30g, motherwort 30g, Radix Codonopsis 30g, bighead atractylodes rhizome 25g, Chinese yam 25g, excessive Sheep leaves of pulse plants 30g, saline cistanche 20g, cloves 15g.
Embodiment 2
Voluminous three sub- balls it be made up of the raw material of following weight:
It is fruit of Chinese wolfberry 20g, fruit of glossy privet 30g, Semen Cuscutae 30g, motherwort 30g, Radix Codonopsis 30g, bighead atractylodes rhizome 25g, Chinese yam 25g, excessive Sheep leaves of pulse plants 30g, saline cistanche 20g, cloves 15g.
Embodiment 3(Embodiment 1-2)
Improve the Chinese medicine preparation preparation method of sow fertility:
Refined concentration pan is evaporated under reduced pressure, tender honey elder generation high-temperature heating, then slow fire persistently refined, made temperature up to 110-116 DEG C, There is the glossiness foam of light red, relatively by force, but without white silk, now water content should lose water to the viscosity picked up with hand in 15-20% Divide about 10-13%, filter impurity, density is 1.4-1.5 at 15 degree after cooling.
By prescription Chinese herbal ultra-fine powder(Cross 300 mesh sieves)It is well mixed, refined honey is equably rubbed with medicinal powder in mixer first Close, now the temperature of refined honey should be 65-70 DEG C, it is fully and even, make its it is inside and outside all moisten, color and luster is consistent, neither too hard, nor too soft, can be with Meaning kneading model, does imaging surface group sample ball block.Bolus are made spheroidal using ball-type film laminator, the gradually general system in spherical mold Into prescribed level, the pill of ball weight, finally obtained final product using freeze-drying.Using Freeze Drying Technique can more preferable curable type, and Keep drug effect.
Quality inspection packaging honeyed bolus shall be rounded up uniformly, color and luster unanimously, especially should be fine and smooth, neither too hard, nor too soft.Water content control is in 10-12% Packaging is wrapped using the ball one of paraffin paper one, and 15 balls fill a polyethylene plastic bag vacuum packaging.

Claims (5)

1. it is a kind of improve fertility of sow Chinese medicine preparation, it is characterised in that it is made up of the dry product of following raw material medicaments, each taste Weight shared by medicine is as follows:
Fruit of Chinese wolfberry 20-30g, fruit of glossy privet 20-35g, Semen Cuscutae 25-35g, motherwort 20-40g,
Radix Codonopsis 25-35g, bighead atractylodes rhizome 20-40g, Chinese yam 20-50g, barrenwort 25-35g,
Saline cistanche 20-30g, cloves 15-20g.
2. the Chinese medicine preparation described in claim 1, it is characterised in that it is made up of the raw material of following weight:
Fruit of Chinese wolfberry 20g, fruit of glossy privet 30g, Semen Cuscutae 30g, motherwort 30g, Radix Codonopsis 30g,
Bighead atractylodes rhizome 25g, Chinese yam 25g, barrenwort 30g, saline cistanche 20g, cloves 15g.
3. the preparation method of Chinese medicine preparation described in any one of claim 1-2, it is characterised in that carried out by the steps:
(1)The preparation method of honeyed bolus:
Chinese medicine was crushed into 300 mesh sieves by various broken technologies of medicinal material low-temperature submicron powder standby;Then by plurality of Chinese Ultramicro-powder The spherical oral solid preparation that end mixes and be made with the jujube flower honey through refining;What the described jujube flower honey refined referred to It is:Refined concentration pan is evaporated under reduced pressure, tender honey elder generation high-temperature heating, then slow fire persistently refined, made temperature up to 110~116 DEG C, There is the glossiness foam of light red, relatively by force, but without white silk, now water content should lose water to the viscosity picked up with hand in 15-20% Divide about 10-13%, filter impurity, density is 1.4-1.5 at 15 DEG C after cooling;
(2)Close medicine pelletization:
Prescription Chinese herbal ultra-fine powder is well mixed, refined honey is equably integrated with medicinal powder in mixer first, honey is added while hot, It is fully and even, make its it is inside and outside all moisten, color and luster is consistent, neither too hard, nor too soft, can random kneading model, by bolus using ball-type press mold Machine is made spheroidal, gradually general in spherical mold to be made prescribed level, the pill of ball weight, is finally obtained final product using freeze-drying;
(3)Quality inspection is packed:
Honeyed bolus shall be rounded up uniformly, color and luster it is consistent, especially should be fine and smooth, neither too hard, nor too soft, water content control uses paraffin paper in 10-12% packagings One ball one is wrapped, and 15 balls fill a polyethylene plastic bag vacuum packaging.
4. described in claim 1 improve sow fertility Chinese medicine preparation improve litter size, the number of live births, Nest produces the application in terms of healthy and strong son's number and nascent nest counterpoise.
5. the application described in claim 4, the sow fertility that carries therein is referred to:Farrowing rate, produce son's rate living, strong son's rate and Nascent nest counterpoise.
CN201710139877.2A 2017-03-10 2017-03-10 A kind of Chinese medicine preparation for improving sow fertility and preparation method and application Pending CN106822535A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710139877.2A CN106822535A (en) 2017-03-10 2017-03-10 A kind of Chinese medicine preparation for improving sow fertility and preparation method and application

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710139877.2A CN106822535A (en) 2017-03-10 2017-03-10 A kind of Chinese medicine preparation for improving sow fertility and preparation method and application

Publications (1)

Publication Number Publication Date
CN106822535A true CN106822535A (en) 2017-06-13

Family

ID=59144137

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201710139877.2A Pending CN106822535A (en) 2017-03-10 2017-03-10 A kind of Chinese medicine preparation for improving sow fertility and preparation method and application

Country Status (1)

Country Link
CN (1) CN106822535A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113508871A (en) * 2021-08-09 2021-10-19 黑龙江省农业科学院畜牧研究所 Natural plant additive for improving reproductive performance of sows and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
曹国文等: "复方女贞子散对繁殖母猪生产性能与哺乳仔猪生长性能的影响", 《饲料工业》 *
艾国良: "中草药饲料添加剂提高母猪繁殖性能的研究", 《湖南农业大学学报》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113508871A (en) * 2021-08-09 2021-10-19 黑龙江省农业科学院畜牧研究所 Natural plant additive for improving reproductive performance of sows and preparation method thereof

Similar Documents

Publication Publication Date Title
CN101167918B (en) Traditional Chinese medicinal preparation for increasing immunity of pig or poultry
CN102783585B (en) Feed for improving reproductive performance of sows
CN102488105B (en) Health care feed additive for farrowing sows and preparation method thereof
CN106071224A (en) A kind of Chinese herbal feed additive for improving sow lactogenic reproductive performance and preparation method thereof
CN101623056A (en) Chinese herbal medicine feed additive for ewes
CN101731488A (en) Chinese medicinal herb additive for preventing post-weaning diarrhea and pig feed thereof
CN105106313A (en) Chinese herbal medicine preparation for enhancing lactation and reproduction functions of sows
CN101869224A (en) Feed additive for improving lactation performance of lactating sows and preparation method thereof
CN103394053A (en) Traditional Chinese medicine composition capable of preventing and treating piglet yellow and white scours as well as preparation and applications thereof
CN101579119A (en) Nutritional food with function of relaxing bowel and preparation method thereof
CN102895319A (en) Composition containing desert cistanche, cynomorium or medlar, pumpkin seeds and pollen
CN108030808A (en) A kind of pulvis using lotus leaf as the prevention Diseases of Cow syndrome of main component
CN105146228A (en) Chinese herb compound preparation used for sow miscarriage prevention and preparing method thereof
CN108096443B (en) Medicine for eliminating toxins in livestock and poultry and improving immunity of organism, preparation method and application thereof
CN103585479A (en) Blood-replenishing pill and blood-replenishing capsule for treating iron-deficiency anemia
CN106822535A (en) A kind of Chinese medicine preparation for improving sow fertility and preparation method and application
CN103202894B (en) Chinese herbal medicine feed additive for preventing and curing infectious serositis of duck
Saparova et al. The effectiveness of phytobiotic additives in the diet of sheep
CN106212901A (en) Improve health-care feed of Trionyx sinensis Wiegmann immunity and preparation method thereof
CN103006967A (en) Chinese medicinal composition for treating metritis of sow
CN110664896A (en) Anti-stress sudden death prevention compound fermentation traditional Chinese medicine additive and preparation method and application thereof
CN106342753B (en) A kind of expanding propagation method of beef cattle
CN104970220A (en) Compound feed for sows in suckling period and preparation method thereof
CN103222565B (en) Traditional chinese medicine milk increasing agent
CN106260734A (en) A kind of 13 week old young bird chicken feeds

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20170613