CN106822353A - A kind of Chinese medicine composition for treating the proliferation of mammary gland - Google Patents
A kind of Chinese medicine composition for treating the proliferation of mammary gland Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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Abstract
The present invention relates to a kind of Chinese medicine composition for treating the proliferation of mammary gland.Chinese medicine composition of the present invention is prepared from by the raw material of following weight portion：6 14 parts of Radix Angelicae Sinensis, 6 14 parts of Ligusticum wallichii, 6 14 parts of the radix paeoniae rubrathe, 6 14 parts of radix rehmanniae recen, 6 14 parts of selfheal, 6 14 parts of honeysuckle, 6 14 parts of the capsule of weeping forsythia, 39 parts of pangolin, 6 14 parts of spina gleditsiae, 6 14 parts of the Radix Astragali, 6 14 parts of the red sage root, 6 14 parts of Radix Glycyrrhizae., for proliferation of mammary gland effect is significant, prescription is smaller, easy to control the quality, and medicinal material is with low cost, suitable for industrial for Chinese medicine composition of the present invention.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines, more particularly to a kind of Chinese medicine composition for treating the proliferation of mammary gland.
Background technology
Cyclomastopathy refers to breast epithelium and proliferation of fibrous tissue, breast tissue conduit and newborn leaflet moving back in structure
The change of row venereal disease and the growth of progressive connective tissue, its pathogenic factor are lacked of proper care mainly due to endocrine hormone.Cyclomastopathy
It is the most common breast disease of women, its incidence of disease accounts for the first place of mammary gland disease.The sick incidence of disease was in and rose year by year in the last few years
Trend, the age also increasingly becomes younger.There are about 70%~80% women according to investigations has the different degrees of proliferation of mammary gland, many
See the women of 25~45 years old.
Doctor trained in Western medicine thinks mammary gland in the presence of endocrine hormone, particularly female/progestational hormone, with the change of menstrual cycle,
Have hyperplasia and the change returnd to the past.Cause endocrine hormone metabolic imbalance, estrogen level to increase for some reason, can go out
Excessively and subinvolution, after after a while, the breast tissue of hyperplasia can not disappear completely, with regard to shape for existing mammoplasia
Into cyclomastopathy.The traditional Chinese medical science thinks that cyclomastopathy starts from liver depression, and then blood stasis phlegm congeals into block, controls suitable dispersing stagnated hepatoqi, promoting blood circulationization
The stasis of blood, softening and resolving hard mass, radix bupleuri, the root of herbaceous peony, rhizoma cyperi, tangerine leaf, the red sage root, earthworm are the common medicine in tcm prescription.Some patients can also take
With Chinese patent drug, such as：Dissipating bind spirit, newborn block disappear, breast is peaceful, RUKANG PIAN, Xiaoyao San or Danzhi Xiaoyao San (Jiawei Xiaoyao San) etc..Department is rich
Spring, Liu Yali etc. are in January, 1979 to the Chinese medicine breast of December CJFD (CNKI) collection in 2009
Gland hyperplasia document, by frequency analysis induction and conclusion syndrome and Medicinal Trait, to analyse proliferation of mammary gland differentiation of tcm rule.
Result shows to be related to 34, card type, and it is Common Syndromes type to be coagulated with stagnation of QI due to depression of the liver, Chong and Ren channel disorder, stagnation of the circulation of vital energy phlegm, accounts for 58.68%, syndrome group
Into to have 16, wherein real example accounts for 84.55%, and asthenic symptoms account for 15.45%.The taste of medication 275, is classified as 43 classes, further by function
19 major classes are merged into, drug for invigorating blood circulation and eliminating stasis, qi-restoratives medicine and expectorants, antitussives and anti-asthmatics medicine frequency of use account for 59.48%, and drug for invigorating blood circulation and eliminating stasis is
First, qi-restoratives medicine takes second place；Come the medicine of first 16 have radix bupleuri, Radix Angelicae Sinensis, rhizoma cyperi, pangolin, root tuber of aromatic turmeric, RADIX PAEONIAE ALBA, fritillaria thunbergii,
Curcuma zedoary, selfheal, Rhizoma Sparganii, corydalis tuber, rascal, oyster, the red sage root, the seed of cowherb, barrenwort, radix bupleuri using occupy all medications it
It is first.It is many with harmonizing prescription, qi-regulating prescription, blood-regulating prescription as main ingredient although the treatment proliferation of mammary gland has more than 300 kinds of prescription.Inventor studies intensively
More than 30 years of TCM Gynecology illness, the therapeutic rules to the proliferation of mammary gland are fruitful, and from Chinese medicine proved recipe is intended, by clinical for many years real
Trample curative effect highly significant.
The content of the invention
In order to solve the above-mentioned technical problem, it is an object of the invention to provide a kind of Chinese medicine composition for treating the proliferation of mammary gland.
The purpose of the present invention is achieved through the following technical solutions：
The present invention provides a kind of Chinese medicine composition for treating the proliferation of mammary gland, the composition be by following weight than raw material
Composition：Radix Angelicae Sinensis 6-14 parts, Ligusticum wallichii 6-14 parts, radix paeoniae rubrathe 6-14 parts, radix rehmanniae recen 6-14 parts, selfheal 6-14 parts, honeysuckle 6-14 parts,
Capsule of weeping forsythia 6-14 parts, pangolin 3-9 parts, spina gleditsiae 6-14 parts, Radix Astragali 6-14 parts, red sage root 6-14 parts, Radix Glycyrrhizae 6-14 parts.
Preferably, the composition by following weight than raw material constitute：Radix Angelicae Sinensis 8-12 parts, Ligusticum wallichii 8-12 parts, the radix paeoniae rubrathe
8-12 parts, radix rehmanniae recen 8-12 parts, selfheal 8-12 parts, honeysuckle 8-12 parts, capsule of weeping forsythia 8-12 parts, pangolin 4-8 parts, spina gleditsiae 8-
12 parts, Radix Astragali 8-12 parts, red sage root 8-12 parts, Radix Glycyrrhizae 8-12 parts.
Still more preferably, the composition by following weight than raw material constitute：10 parts of Radix Angelicae Sinensis, 10 parts of Ligusticum wallichii is red
10 parts of Chinese herbaceous peony, 10 parts of radix rehmanniae recen, 10 parts of selfheal, 10 parts of honeysuckle, 10 parts of the capsule of weeping forsythia, 6 parts of pangolin, 10 parts of spina gleditsiae, the Radix Astragali 10
Part, 10 parts of the red sage root, 10 parts of Radix Glycyrrhizae.
Still more preferably, the composition by following weight than raw material constitute：12 parts of Radix Angelicae Sinensis, 12 parts of Ligusticum wallichii is red
10 parts of Chinese herbaceous peony, 8 parts of radix rehmanniae recen, 10 parts of selfheal, 12 parts of honeysuckle, 12 parts of the capsule of weeping forsythia, 4 parts of pangolin, 12 parts of spina gleditsiae, the Radix Astragali 10
Part, 8 parts of the red sage root, 12 parts of Radix Glycyrrhizae.
Still more preferably, the composition by following weight than raw material constitute：10 parts of Radix Angelicae Sinensis, 10 parts of Ligusticum wallichii is red
12 parts of Chinese herbaceous peony, 12 parts of radix rehmanniae recen, 12 parts of selfheal, 12 parts of honeysuckle, 10 parts of the capsule of weeping forsythia, 4 parts of pangolin, 12 parts of spina gleditsiae, the Radix Astragali 10
Part, 10 parts of the red sage root, 10 parts of Radix Glycyrrhizae.
Preferably, the Chinese medicine composition described in any of the above, needs to be prepared into corresponding Clinical Dosage Form according to clinic.
Medicinal material effect used above is as follows：
Radix Angelicae Sinensis：Enrich blood；Promoting blood circulation；Menstruction regulating and pain relieving；Moisturize laxation.The main all cards of the deficiency of blood；Irregular menstruation；Amenorrhea；Dysmenorrhoea；Abdominal mass knot
It is poly-；Uterine bleeding；Asthenia cold abdominalgia；Impotence numbness；Numbness；Intestines are dry and shit is difficult；Weight after dysentery characterized by blood in the stool；Ulcer sores；Injury from falling down.
Ligusticum wallichii：Blood-activating and qi-promoting, wind-expelling pain-stopping.For irregular menstruation, closed dysmenorrhea , Disorder lump in the abdomen is suffered from abdominal pain, chest side of body shouting pain is fallen and flutters swollen
Bitterly, have a headache, arthralgia pain due to rheumatism.
The radix paeoniae rubrathe：Clearing heat and cooling blood, blood stasis removing analgesic.For febrile virulent maculae, hematemesis and epistaxis, red eye, swell pain, liver-depressed hypochondrium pain, Amenorrhea is bitterly
Through note of the ancient Chinese lump in the abdomen stomachache, injury from falling down, carbuncle swells sore.
Radix rehmanniae recen：Clearing heat and cooling blood, yin-nourishing is promoted the production of body fluid.For the deep red polydipsia of pyreticosis tongue, yin asthenia generating intrinsic heat, hectic fever due to yin labor heat, interior heat disappears
Yearningly, spit blood, bleeding from five sense organs or subcutaneous tissue, spot dermexanthesis.
Selfheal：Clear liver and improve vision；Powder detoxifcation.Argument also photophobia；Ophthalmalgia；Dizziness of having a headache；Tinnitus；Scrofula；Goiter and tumor；
Acute mastitis；Mumps；Carbuncle furuncle poison；Acute hepatitis, chronic hepatitis；High blood pressure.
Honeysuckle：It is clearing heat and detoxicating.Main warm disease heating；Toxic-heat and blood stasis；Carbuncle swells furunculosis；Larynx numbness and multi-infection disease.
The capsule of weeping forsythia：Ulcer, scrofula, acute mastitis, erysipelas, anemopyretic cold, warm disease is from the beginning of warm is joined the army, hyperpyrexia polydipsia, coma hair
Spot, heat gonorrhea renal shutdown.
Pangolin：Blood circulation promoting and dispersing pathogen accumulation；Stimulate the menstrual flow lower breast；Anti-stain in solid.Main blood stasis is through closing；Abdominal mass；Arthralgia pain due to rheumatism；Agalactia；
Carbuncle swells；Scrofula.
Spina gleditsiae：Sterilize purulence；Search wind；Desinsection.Main swollen ulcer drug；Scrofula；Sore rash stubborn dermatitis；Hypogalactia after delivery；Retention of afterbirth；
Pestilential wind.
The Radix Astragali：Invigorating qi for strengthening superficies, diuretic and maintain drug, apocenosis, expelling pus and promoting granulation.For treatment deficiency of vital energy weak, anorexia and loose stool, the sinking of qi of middle-jiao,
Rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy oedema, ulcer is difficult to burst, burst for a long time and does not holds back, flaccidity of limbs due to deficiency of blood is yellow, Heat Diabetes；It is chronic
Nephritic proteinuria, diabetes.
The red sage root：Stasis-dispelling and pain-killing, invigorate blood circulation, relieving restlessness that clears away heart-fire.For irregular menstruation, closed dysmenorrhea, the accumulation of note of the ancient Chinese lump in the abdomen, chest and abdomen thorn
Bitterly, hot numbness pain, sore swell and ache curative, dysphoria and insomnia；Hepatosplenomegaly, angina pectoris.
Radix Glycyrrhizae：It is clearing heat and detoxicating, moisten the lung and relieve the cough, coordinating the drug actions of a prescription；Honey-fried licorice root can invigorate the spleen and benefit qi.Abscess of throat is cured mainly, is coughed, spleen
Stomach weakness, taste-blindness rate, hepatitis, hysteria, carbuncle furuncle poison, medicine and food poisoning.
Chinese traditional medicine composition object space solution of the present invention：With Radix Angelicae Sinensis, Ligusticum wallichii, the red sage root and pangolin promoting blood circulation as monarch drug in a prescription in side；Ministerial drug
The Radix Astragali, Radix Glycyrrhizae are equipped with tonifying middle-Jiao and Qi, with clearing heat and cooling blood and tonifying yin, simultaneous the applying of four medicines can principal drug assistance promoting blood circulation to remove blood stasis for the radix paeoniae rubrathe, radix rehmanniae recen
Work(；Assistant is clearing heat and detoxicating with honeysuckle, the capsule of weeping forsythia, while helping into the spina gleditsiae saturating purulence of sterilization；Search wind；Make medicine with selfheal, enter Liver Channel
And dissipating bind, play a part of to lead medicine and enter through enabling all medicine drug effects to play with all strength.
Beneficial effects of the present invention：
Cyclomastopathy starts from liver depression, and then blood stasis phlegm congeals into block, controls suitable dispersing stagnated hepatoqi, promoting blood circulation and removing blood stasis, softening and resolving hard mass.But
We look for another way, and legislation is not discongested based on edema with the liver involved, to medicines such as radix bupleuri, rhizoma cyperi, root tubers of aromatic turmeric, but " rushing down its son actually ", use
With promoting blood circulation and removing blood stasis, clearing heat and detoxicating medicine, with let out the heart, lung it is hot and suffocating, liver is from discongesting.Through clinical verification cure rate for many years up to 98% with
On, and Chinese prescription flavour of a drug of the invention are less, it is easy to control the quality, and belong to common medicinal material, it is easy to obtain, it is with low cost, suitably
Industrialization.
Specific embodiment
The following is the specific embodiment of present invention, for illustrating the skill that technical problem is solved in present specification
Art scheme, contributes to skilled artisan understands that present invention, but the realization of technical solution of the present invention is not limited to these
Embodiment.
Embodiment 1 treats the Chinese medicine composition of the proliferation of mammary gland
Radix Angelicae Sinensis 6g, Ligusticum wallichii 14g, radix paeoniae rubrathe 14g, radix rehmanniae recen 14g, selfheal 6g, honeysuckle 14g, capsule of weeping forsythia 6g, pangolin 9g,
Spina gleditsiae 6g, Radix Astragali 14g, red sage root 6g, Radix Glycyrrhizae 14g.This be it is every take dosage, directly decoct soup can take.
Embodiment 2 treats the Chinese medicine composition of the proliferation of mammary gland
Radix Angelicae Sinensis 14g, Ligusticum wallichii 6g, radix paeoniae rubrathe 6g, radix rehmanniae recen 6g, selfheal 14g, honeysuckle 6g, capsule of weeping forsythia 14g, pangolin 3g, soap
14g, Radix Astragali 6g, red sage root 14g, Radix Glycyrrhizae 6g are pierced in angle.This be it is every take dosage, directly decoct soup can take.
Embodiment 3 treats the Chinese medicine composition of the proliferation of mammary gland
Radix Angelicae Sinensis 8g, Ligusticum wallichii 8g, radix paeoniae rubrathe 12g, radix rehmanniae recen 8g, selfheal 12g, honeysuckle 8g, capsule of weeping forsythia 12g, pangolin 4g, soap
12g, Radix Astragali 12g, red sage root 8g, Radix Glycyrrhizae 12g are pierced in angle.This be it is every take dosage, directly decoct soup can take.
Embodiment 4 treats the Chinese medicine composition of the proliferation of mammary gland
Radix Angelicae Sinensis 12g, Ligusticum wallichii 12g, radix paeoniae rubrathe 8g, radix rehmanniae recen 12g, selfheal 8g, honeysuckle 12g, capsule of weeping forsythia 8g, pangolin 8g,
Spina gleditsiae 8g, Radix Astragali 12g, red sage root 8g, Radix Glycyrrhizae 8g.This be it is every take dosage, directly decoct soup can take.
Embodiment 5 treats the Chinese medicine composition of the proliferation of mammary gland
Radix Angelicae Sinensis 10g, Ligusticum wallichii 10g, radix paeoniae rubrathe 10g, radix rehmanniae recen 10g, selfheal 10g, honeysuckle 10g, capsule of weeping forsythia 10g, pangolin
6g, spina gleditsiae 10g, Radix Astragali 10g, red sage root 10g, Radix Glycyrrhizae 10g.This be it is every take dosage, directly decoct soup can take.
Embodiment 6 treats the Chinese medicine composition of the proliferation of mammary gland
Radix Angelicae Sinensis 12g, Ligusticum wallichii 12g, radix paeoniae rubrathe 10g, radix rehmanniae recen 8g, selfheal 10g, honeysuckle 12g, capsule of weeping forsythia 12g, pangolin
4g, spina gleditsiae 12g, Radix Astragali 10g, red sage root 8g, Radix Glycyrrhizae 12g.
Embodiment 7 treats the Chinese medicine composition of the proliferation of mammary gland
Radix Angelicae Sinensis 10g, Ligusticum wallichii 10g, radix paeoniae rubrathe 12g, radix rehmanniae recen 12g, selfheal 12g, honeysuckle 12g, capsule of weeping forsythia 10g, pangolin
4g, spina gleditsiae 12g, Radix Astragali 10g, red sage root 10g, Radix Glycyrrhizae 10g.
In order to confirm significant curative effect of the invention, the proliferation of mammary gland patient that my 2006-2016 sees and treat patients between 10 years is counted
Case has 827 people, and only taking traditional Chinese medicine composition for treating cured person of the invention has 769 people, and other have other accompanying symptoms, needs another
Row conditioning is cured.It is random below to take passages medical case notes in the past：
Case 1
Zhang, female, 43 years old, Xi'an people from An County long suffered from the proliferation of mammary gland for many years, has lump pain, once western medicine treatment effect
Do not take a turn for the better, coming here carries out Chinese medicine, after taking 1 course for the treatment of of Chinese medicine composition of embodiment 6, pain lump symptom disappears substantially
Lose, taking medicine continuously half a year is almost recovered, and is paid a return visit without recurrence after 1 year.
Case 2
Lee, female, 38 years old, Xianyang people from Liquan County, for many years breast there is lump, menstruation fore udder distending pain is extenuated after.
It is weak with the soreness of waist, tired, insomnia and dreamful sleep, loose stool.Tongue is weak, tongue is white, deep thready pulse.Take Chinese medicine composition reality of the invention
2 courses for the treatment of of decoction of example 4 are applied, feels that lump diminishes, the weak symptom mitigation of the soreness of waist, continuous to take 3 courses for the treatment of, spirit improves, and lump is bright
It is aobvious to reduce；Consolidate again and take 2 courses for the treatment of, eumenorrhea, lump disappears, stool is normal, sleep recovers normal, recovery from illness, after a year
Pay a return visit without recurrence.
Case 3
Xue, female, 45 years old, Xianyang people from Qian County, pharmaceutical factory workman, patient finds breast in unit physical examination scleroma, local
City's hospital admission, through color ultrasound, arranged on left and right sides is broken forth 1 tubercle respectively, with regular throe, takes 'rukuaixiao ' tablet treatment 3
The individual course for the treatment of, effect on driving birds is not good is come here and is treated upon somebody's introduction.After taking decoction 2 courses for the treatment of of treatment of the embodiment of the present invention 5,
Symptom mitigation, breast rhabdion disappears, 2 courses for the treatment of of continual cure, and symptom when medical disappears, and by color ultrasound examination, breast is hard
Knot is disappeared, and cures completely, and follow-up is not recurred after 1 year.
Claims (6)
1. a kind of Chinese medicine composition for treating the proliferation of mammary gland, it is characterised in that the composition be by following weight than raw material
Composition：Radix Angelicae Sinensis 6-14 parts, Ligusticum wallichii 6-14 parts, radix paeoniae rubrathe 6-14 parts, radix rehmanniae recen 6-14 parts, selfheal 6-14 parts, honeysuckle 6-14 parts,
Capsule of weeping forsythia 6-14 parts, pangolin 3-9 parts, spina gleditsiae 6-14 parts, Radix Astragali 6-14 parts, red sage root 6-14 parts, Radix Glycyrrhizae 6-14 parts.
2. Chinese medicine composition according to claim 1, it is characterised in that the composition be by following weight than raw material
Composition：Radix Angelicae Sinensis 8-12 parts, Ligusticum wallichii 8-12 parts, radix paeoniae rubrathe 8-12 parts, radix rehmanniae recen 8-12 parts, selfheal 8-12 parts, honeysuckle 8-12 parts,
Capsule of weeping forsythia 8-12 parts, pangolin 4-8 parts, spina gleditsiae 8-12 parts, Radix Astragali 8-12 parts, red sage root 8-12 parts, Radix Glycyrrhizae 8-12 parts.
3. Chinese medicine composition according to claim 2, it is characterised in that the composition be by following weight than raw material
Composition：10 parts of Radix Angelicae Sinensis, 10 parts of Ligusticum wallichii, 10 parts of the radix paeoniae rubrathe, 10 parts of radix rehmanniae recen, 10 parts of selfheal, 10 parts of honeysuckle, 10 parts of the capsule of weeping forsythia is worn
6 parts of naze, 10 parts of spina gleditsiae, 10 parts of the Radix Astragali, 10 parts of the red sage root, 10 parts of Radix Glycyrrhizae.
4. Chinese medicine composition according to claim 2, it is characterised in that the composition be by following weight than raw material
Composition：12 parts of Radix Angelicae Sinensis, 12 parts of Ligusticum wallichii, 10 parts of the radix paeoniae rubrathe, 8 parts of radix rehmanniae recen, 10 parts of selfheal, 12 parts of honeysuckle, 12 parts of the capsule of weeping forsythia wears mountain
4 parts of first, 12 parts of spina gleditsiae, 10 parts of the Radix Astragali, 8 parts of the red sage root, 12 parts of Radix Glycyrrhizae.
5. Chinese medicine composition according to claim 2, it is characterised in that the composition be by following weight than raw material
Composition：10 parts of Radix Angelicae Sinensis, 10 parts of Ligusticum wallichii, 12 parts of the radix paeoniae rubrathe, 12 parts of radix rehmanniae recen, 12 parts of selfheal, 12 parts of honeysuckle, 10 parts of the capsule of weeping forsythia is worn
4 parts of naze, 12 parts of spina gleditsiae, 10 parts of the Radix Astragali, 10 parts of the red sage root, 10 parts of Radix Glycyrrhizae.
6. according to any Chinese medicine compositions of claim 1-5, it is characterised in that the Chinese medicine composition needs system according to clinic
It is standby into corresponding Clinical Dosage Form.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108057088A (en) * | 2018-02-02 | 2018-05-22 | 彭顺文 | A kind of herbal composite for treating mammary gland disease and preparation method thereof |
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| CN108057088A (en) * | 2018-02-02 | 2018-05-22 | 彭顺文 | A kind of herbal composite for treating mammary gland disease and preparation method thereof |
| CN108057088B (en) * | 2018-02-02 | 2021-01-19 | 彭顺文 | A Chinese medicinal composition for treating mammary gland diseases, and its preparation method |
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