CN106821463B - A kind of real-time display punctures the ultrasound image guidance system and its application method of pin position - Google Patents
A kind of real-time display punctures the ultrasound image guidance system and its application method of pin position Download PDFInfo
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- CN106821463B CN106821463B CN201710112791.0A CN201710112791A CN106821463B CN 106821463 B CN106821463 B CN 106821463B CN 201710112791 A CN201710112791 A CN 201710112791A CN 106821463 B CN106821463 B CN 106821463B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3403—Needle locating or guiding means
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/34—Trocars; Puncturing needles
- A61B17/3403—Needle locating or guiding means
- A61B2017/3413—Needle locating or guiding means guided by ultrasound
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Abstract
The invention discloses ultrasound image guidance systems and its application method that a kind of real-time display punctures pin position, guidance system includes ultrasonic image diagnosis instrument, calculus thought and harmonic oscillator, calculus thought is connect with harmonic oscillator, the calculus thought includes wrapping layer, two outer layers and middle layer, two outer layers are oppositely arranged, the upper and lower surface of middle layer is connect with two outer layers respectively by conducting resinl, the outer layer is made of insulating layer and electrode layer, the middle layer is made of separation layer and piezoelectric patches, and one end of separation layer is arranged in the piezoelectric patches；The wrapping layer is PDMS (dimethyl silicone polymer) layer coated in two outer layer outer surfaces.The present invention can identify in real time the cutting tip present position of puncture needle in the image that ultrasonic image diagnosis instrument is shown, while its structure is simple, easy to use, cost is relatively low, convenient for the study of operator.
Description
Technical field
It is specifically a kind of real-time the present invention relates to guidance system and its application method that a kind of real-time display punctures pin position
Display punctures the ultrasound image guidance system and its application method of pin position.
Background technique
Percutaneous fine needle puncture biopsy or suction (such as in conjunction with various endoscopes) in vitro or in vivo
It is widely used in clinical diagnosis, this technology is safer compared with the biopsy of open operation formula, and wound is small.This
Outside, fine needle also can be applied to treatment (such as the pin type cancer ablation by microwave and radio frequency).Utilize existing clinical imaging side
Method (such as CT (CT scan), MRI (Magnetic resonance imaging) and ultrasonic imaging), the operation that living tissue punctures
Person can in real time by the position of the image viewing biopsy needle of display, and with this information guidance adjustment puncture needle movement
Direction makes it gradually advance to target area.In these imaging patterns, the preferential bootstrap technique for selecting ultrasonic imaging, this master
Relative to CT and MRI to have the advantages that unionized, non-radiation type, low cost, mobility and high frame rate due to ultrasonic wave.
But its resolution ratio of the image due to showing after ultrasonic scanning is lower, while the diameter of general puncture needle smaller (is especially worn
Pricker end diameter is minimum), therefore puncture clearly can not be reliably shown in the image that ultrasonic wave is shown when being punctured
The position of needle (or part display puncture needle) in turn can not be accurately positioned the position for puncturing end of puncture needle, eventually lead to this
Image can not play guiding function to the puncture working of operator.In image-guided kidney biopsy, the accuracy rate of CT
It is 93.8%, and the analog value of ultrasonic examination is 76.4%.In the success rate of B-ultrasound thyroid biopsy
It is 68% to 96.6%.Biopsy dislocation can lead to puncture needle repeatedly be inserted into, it is longer check and Diagnostic Time, to it
The unnecessary damage of hetero-organization or organ and the operation of multiplicating property.
Several system and methods have been developed in industry at present and have punctured fine needle to improve in the case where ultrasonic imaging guides
Visualization.One of system and method is the position data label target and its surrounding group with two-dimentional real-time ultrasound wave imaging
The three-dimensional structure knitted is used to puncture the navigation of body, at the same in ultrasonic probe and conduit the multiple sensors of insertion (such as electromagnetism and
Optical sensor) for determining the accurate location of puncture needle cutting tip (i.e. syringe needle), and the real-time display on ultrasonography
Current location and prediction locus.In the No operation environment that worst error is 2.96 millimeters, the position precision of system estimation is reachable
To 0.71 ± 0.43mm.Although this mode makes ultrasonography can determine the real time position of puncture needle, but it is not only needed
In addition the support of multiple sensors and hardware is also required to the support of corresponding ultrasonic imaging system, and to each different inspections
Body is both needed to detection and punctures the three-dimensional structure of target point surrounding tissue for puncturing the navigation of body；This mode is real for these reasons
It applies complexity, be not easy to operator's study, higher cost, and once break down and can not be repaired as early as possible.
Summary of the invention
The ultrasonic wave for puncturing pin position in view of the above existing problems in the prior art, the present invention provides a kind of real-time display draws
Guiding systems and its application method can be identified in real time in the image that ultrasonic image diagnosis instrument is shown locating for the cutting tip of puncture needle
Position, while its structure is simple, easy to use, cost is relatively low, convenient for the study of operator.
To achieve the goals above, the technical solution adopted by the present invention is that: this kind of real-time display punctures the ultrasound of pin position
Image guidance system, including ultrasonic image diagnosis instrument, calculus thought and harmonic oscillator, calculus thought and harmonic oscillator connect
It connects, the calculus thought includes wrapping layer, two outer layers and middle layer, and two outer layers are oppositely arranged, the upper and lower surface of middle layer
It is connect respectively with two outer layers by conducting resinl, the outer layer is made of insulating layer and electrode layer, and the middle layer is by separation layer
It is formed with piezoelectric patches, one end of separation layer is arranged in the piezoelectric patches；The wrapping layer is coated in two outer layer outer surfaces
PDMS (dimethyl silicone polymer) layer；There is good biocompatibility using PDMS film, and make device and electric conductivity body
Liquid isolation.
Further, the piezoelectric patches is PZT (lead zirconate titanate) piezoelectric ceramic piece.
Further, the material of the separation layer and insulating layer is LCP (liquid crystal polymer).
Further, the conducting resinl is conductive epoxy resin.
A kind of preparation method of calculus thought, specific steps are as follows:
A, it prepares outer layer: electrode layer and insulating layer is bonded into one；
B, it sets middle layer: one end that separation layer is arranged in piezoelectric patches is formed into middle layer；
C, it prepares composite layer: middle layer being placed among the outer layer that two are oppositely arranged, and will be intermediate by conducting resinl
Layer is bonded with outer layer；
D, prepare wrapping layer: in composite layer outer surface, coating PDMS layer forms wrapping layer；
E, it curing process: puts it into bake 2 hours at 80 DEG C in baking oven after completing step D and is solidified；
F, polarization process: the piezoelectric patches after solidification is polarized 5 minutes under 225V voltage, is then polarized under 450V voltage
To realize piezoelectric effect, the preparation process of calculus thought is completed within 15 minutes.
A kind of application method of the B-ultrasound system of real-time display puncture pin position, the specific steps of this method are as follows:
A, the resonance frequency of calculus thought in this guidance system, the sine wave of the resonance frequency are measured by impedance analyzer
For driving this calculus thought to make it through piezoelectric patches transmitting ultrasonic wave；
B, after determining resonance frequency, calculus thought is fitted in the outer surface of puncture needle, and is made micro- sharp with piezoelectric patches
Device one end is encouraged close to the cutting tip of puncture needle, the calculus thought other end is connect with harmonic oscillator；
C, the signal that adjustment harmonic oscillator issues keeps it consistent with the resonance frequency sine wave of calculus thought；
D, operator is punctured using puncture needle after opening ultrasonic image diagnosis instrument；
E, it since the ultrasonic wave that the ultrasonic wave that calculus thought issues is issued with ultrasonic image diagnosis instrument interferes, then operates
The image that person is shown by observing ultrasonic image diagnosis instrument, wherein having conical bright fringes line is to interfere generation
Image, and the Circle in Digital Images conical point shown according to principle of interference is the location of piezoelectric patches, is swashed further according to adhesion is micro-
Piezoelectric patches determines the puncture end position of puncture needle in the position of puncture needle when encouraging device；
F, according to the location of cutting tip for determining puncture needle, adjustment punctures direction to operator in real time, is finally reached puncture
Target point.
Compared with prior art, the present invention uses ultrasonic image diagnosis instrument, calculus thought, puncture needle and harmonic oscillator phase
In conjunction with mode, using calculus thought issue ultrasonic wave and ultrasonic image diagnosis instrument issue ultrasonic wave interfere phenomenon,
There is conical bright fringes line since interference phenomenon can be presented in the image that ultrasonic image diagnosis instrument is shown, then according to dry
Relating to principle conical tip is piezoelectric patches, and the cutting tip due to piezoelectric patches close to puncture needle is arranged, it therefore follows that puncture needle
Real time position locating for cutting tip adjusts the guidance for puncturing direction convenient for operator, is finally reached and punctures target point.This mode
Due to being guided using ultrasound image, with unionized, non-radiation type possessed by ultrasonic wave, low cost, mobility
And the advantages of high frame rate；Support of the present invention without multiple sensors and hardware simultaneously, it is in addition corresponding super without modification
The present invention can be realized using common ultrasonic image diagnosis instrument in the hardware and software of acoustic imaging system, therefore applicability is wide
It is general, while cost is relatively low, structure is simple, is also convenient for the use of operator.
Detailed description of the invention
Fig. 1 is micro-exciter appearance schematic diagram in the present invention；
Fig. 2 is the longitudinal sectional view of Fig. 1；
Fig. 3 is the position view that micro-exciter is mounted on puncture needle in the present invention；
Fig. 4 is ultrasonic image diagnosis instrument image when not punctured using the present invention.
Fig. 5 is ultrasonic image diagnosis instrument image when being punctured using the present invention.
In figure: 1, micro-exciter, 2, piezoelectric patches, 3, insulating layer, 4, electrode layer, 5, separation layer, 6, puncture needle.
Specific embodiment
The invention will be further described below.
As shown in Figures 1 to 5, this kind of real-time display punctures the B-ultrasound system of pin position, including ultrasound image is examined
Disconnected instrument, calculus thought 1 and harmonic oscillator, calculus thought 1 are connect with harmonic oscillator, the calculus thought 1 including wrapping layer,
Two outer layers and middle layer, two outer layers are oppositely arranged, and the upper and lower surface of middle layer is connected with two outer layers respectively by conducting resinl
It connects, the outer layer is made of insulating layer 3 and electrode layer 4, and the middle layer is made of separation layer 5 and piezoelectric patches 2, the piezoelectric patches
2 are arranged in one end of separation layer 5；The wrapping layer is the PDMS (dimethyl silicone polymer) coated in two outer layer outer surfaces
Layer；There is good biocompatibility using PDMS film, and make device and electric conductivity fluid sequestration.
Further, the piezoelectric patches 2 is PZT (lead zirconate titanate) piezoelectric ceramic piece.
Further, the material of the separation layer 5 and insulating layer 3 is LCP (liquid crystal polymer).
Further, the conducting resinl is conductive epoxy resin.
A kind of preparation method of calculus thought, specific steps are as follows:
A, it prepares outer layer: electrode layer 4 and insulating layer 3 is bonded into one；
B, it sets middle layer: one end that separation layer 5 is arranged in piezoelectric patches 2 is formed into middle layer；
C, it prepares composite layer: middle layer being placed among the outer layer that two are oppositely arranged, and will be intermediate by conducting resinl
Layer is bonded with outer layer；
D, prepare wrapping layer: in composite layer outer surface, coating PDMS layer forms wrapping layer；
E, it curing process: puts it into bake 2 hours at 80 DEG C in baking oven after completing step D and is solidified；
F, polarization process: the piezoelectric patches 2 after solidification is polarized 5 minutes under 225V voltage, then the pole under 450V voltage
Change 15 minutes to realize piezoelectric effect, completes the preparation process of calculus thought.
A kind of application method of the B-ultrasound system of real-time display puncture pin position, the specific steps of this method are as follows:
A, the resonance frequency of calculus thought 1 in this guidance system, the sine of the resonance frequency are measured by impedance analyzer
Wave is for driving this calculus thought 1 to make it through piezoelectric patches transmitting ultrasonic wave；
B, after determining resonance frequency, calculus thought 1 is fitted in the outer surface of puncture needle, and is made micro- with piezoelectric patches 2
Close to the cutting tip of puncture needle 6,1 other end of calculus thought connect 1 one end of driver with harmonic oscillator；
C, the signal that adjustment harmonic oscillator issues keeps it consistent with the resonance frequency sine wave of calculus thought 1；
D, operator is punctured using puncture needle 6 after opening ultrasonic image diagnosis instrument；
E, it since the ultrasonic wave that the ultrasonic wave that calculus thought 1 issues is issued with ultrasonic image diagnosis instrument interferes, then grasps
The image that author is shown by observing ultrasonic image diagnosis instrument, wherein having conical bright fringes line is to interfere generation
Image, and the Circle in Digital Images conical point shown according to principle of interference is the position of piezoelectric patches 2；
F, operator punctures direction according to the adjustment of the location of the real-time cutting tip for determining puncture needle 6, is finally reached and wears
The point of tattoo.
Claims (4)
1. the ultrasound image that a kind of real-time display punctures pin position guides system, including ultrasonic image diagnosis instrument, which is characterized in that
It further include calculus thought (1) and harmonic oscillator, calculus thought (1) is connect with harmonic oscillator, and the calculus thought (1) includes
Wrapping layer, two outer layers and middle layer, two outer layers are oppositely arranged, the upper and lower surface of middle layer by conducting resinl respectively with two
Outer layer connection, the outer layer are made of insulating layer (3) and electrode layer (4), and the middle layer is by separation layer (5) and piezoelectric patches (2)
Composition, the one end of piezoelectric patches (2) setting in separation layer (5)；The wrapping layer is coated in two outer layer outer surfaces
PDMS layer；Calculus thought (1) is fitted in the outer surface of puncture needle (6), and makes calculus thought (1) one end with piezoelectric patches (2)
Cutting tip close to puncture needle (6), calculus thought (1) other end are connect with harmonic oscillator；When being navigated, harmonic oscillator
Calculus thought (1) is driven to issue ultrasonic wave, while ultrasonic image diagnosis instrument issues the ultrasonic wave of same frequency, calculus thought (1) hair
The ultrasonic wave that ultrasonic wave and ultrasonic image diagnosis instrument out issues interferes phenomenon, and interference phenomenon is aobvious in ultrasonic image diagnosis instrument
Presenting in the image shown has conical bright fringes line, is then to press according to the Circle in Digital Images conical point that principle of interference is shown
Wearing to get puncture needle out (6) is arranged in the location of electric piece (2), the cutting tip due to piezoelectric patches (2) close to puncture needle (6)
Real time position locating for barbed end.
2. the ultrasound image that a kind of real-time display punctures pin position according to claim 1 guides system, feature exists
In the piezoelectric patches (2) is PZT piezoelectric ceramic piece.
3. the ultrasound image that a kind of real-time display punctures pin position according to claim 1 guides system, feature exists
In the material of the separation layer (5) and insulating layer (3) is LCP.
4. the ultrasound image that a kind of real-time display punctures pin position according to claim 1 guides system, feature exists
In the conducting resinl is conductive epoxy resin.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710112791.0A CN106821463B (en) | 2017-02-28 | 2017-02-28 | A kind of real-time display punctures the ultrasound image guidance system and its application method of pin position |
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| CN201710112791.0A CN106821463B (en) | 2017-02-28 | 2017-02-28 | A kind of real-time display punctures the ultrasound image guidance system and its application method of pin position |
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| CN106821463B true CN106821463B (en) | 2019-04-30 |
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| CN111449682A (en) * | 2020-04-17 | 2020-07-28 | 深圳市奥昇医疗科技有限责任公司 | Method, device and equipment for detecting gaps of ablation sites and storage medium |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1435899A (en) * | 2002-01-31 | 2003-08-13 | 丰田自动车株式会社 | Laminated piezoelectric actuator |
| CN202802550U (en) * | 2012-08-31 | 2013-03-20 | 中国科学院深圳先进技术研究院 | Ultrasonic transducer |
| CN105377144A (en) * | 2013-03-15 | 2016-03-02 | 敦提大学校董事会 | Medical apparatus and its visualisation |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1435899A (en) * | 2002-01-31 | 2003-08-13 | 丰田自动车株式会社 | Laminated piezoelectric actuator |
| CN202802550U (en) * | 2012-08-31 | 2013-03-20 | 中国科学院深圳先进技术研究院 | Ultrasonic transducer |
| CN105377144A (en) * | 2013-03-15 | 2016-03-02 | 敦提大学校董事会 | Medical apparatus and its visualisation |
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