CN106821427B - A kind of Novel room is every defect plugging device - Google Patents
A kind of Novel room is every defect plugging device Download PDFInfo
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- CN106821427B CN106821427B CN201710159779.5A CN201710159779A CN106821427B CN 106821427 B CN106821427 B CN 106821427B CN 201710159779 A CN201710159779 A CN 201710159779A CN 106821427 B CN106821427 B CN 106821427B
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- 230000007547 defect Effects 0.000 title claims abstract description 63
- 239000010409 thin film Substances 0.000 claims abstract description 25
- 230000004888 barrier function Effects 0.000 claims abstract description 22
- 229910001092 metal group alloy Inorganic materials 0.000 claims description 30
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 3
- 229910052799 carbon Inorganic materials 0.000 claims description 3
- 239000007787 solid Substances 0.000 claims description 3
- 208000035478 Interatrial communication Diseases 0.000 abstract description 40
- 208000013914 atrial heart septal defect Diseases 0.000 abstract description 40
- 206010003664 atrial septal defect Diseases 0.000 abstract description 40
- 238000013459 approach Methods 0.000 abstract description 3
- 239000010410 layer Substances 0.000 description 20
- 239000008280 blood Substances 0.000 description 8
- 210000004369 blood Anatomy 0.000 description 8
- 238000010586 diagram Methods 0.000 description 8
- 210000002837 heart atrium Anatomy 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 238000001356 surgical procedure Methods 0.000 description 5
- 230000000007 visual effect Effects 0.000 description 4
- 208000007536 Thrombosis Diseases 0.000 description 3
- 229910045601 alloy Inorganic materials 0.000 description 3
- 239000000956 alloy Substances 0.000 description 3
- 238000002583 angiography Methods 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 229910052751 metal Inorganic materials 0.000 description 3
- 230000002980 postoperative effect Effects 0.000 description 3
- 238000002604 ultrasonography Methods 0.000 description 3
- 229920002732 Polyanhydride Polymers 0.000 description 2
- 229920000954 Polyglycolide Polymers 0.000 description 2
- 210000003157 atrial septum Anatomy 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 238000005260 corrosion Methods 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 208000002173 dizziness Diseases 0.000 description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 2
- 239000010931 gold Substances 0.000 description 2
- 229910052737 gold Inorganic materials 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 229910021645 metal ion Inorganic materials 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 229920000747 poly(lactic acid) Polymers 0.000 description 2
- 239000004633 polyglycolic acid Substances 0.000 description 2
- 239000004626 polylactic acid Substances 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 206010007559 Cardiac failure congestive Diseases 0.000 description 1
- 206010008190 Cerebrovascular accident Diseases 0.000 description 1
- 208000002330 Congenital Heart Defects Diseases 0.000 description 1
- 206010019280 Heart failures Diseases 0.000 description 1
- 208000000924 Right ventricular hypertrophy Diseases 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- 206010003119 arrhythmia Diseases 0.000 description 1
- 230000006793 arrhythmia Effects 0.000 description 1
- 230000000747 cardiac effect Effects 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 208000028831 congenital heart disease Diseases 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
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- 238000005516 engineering process Methods 0.000 description 1
- 210000003754 fetus Anatomy 0.000 description 1
- 239000010408 film Substances 0.000 description 1
- 208000025339 heart septal defect Diseases 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
- A61B2017/00588—Rigid or stiff implements, e.g. made of several rigid parts linked by hinges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
- A61B2017/00601—Implements entirely comprised between the two sides of the opening
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
- A61B2017/00606—Implements H-shaped in cross-section, i.e. with occluders on both sides of the opening
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00867—Material properties shape memory effect
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- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
- Prostheses (AREA)
Abstract
The invention discloses a kind of Novel rooms every defect plugging device comprising thin-film barrier layers, first support body, second support body, the first fixedly connected part and the second fixedly connected part.Novel room of the invention provides closed room every the new approaches of defect every defect plugging device, the edge of atrial septal defect is effectively clamped using the clamping force between plugging device, rather than has fixed waist size by the edge closed room of clamping atrial septal defect every defect as existing plugging device.
Description
Technical field
The present invention relates to the field of medical instrument technology, and particularly a kind of Novel room is every defect plugging device.
Background technique
Atrial septal defect is a kind of clinically common congenital heart disease, and lesion characteristic is the room between left atrium
Interval fails normally closed, and blood flows between atrium sinistrum and atrium dextrum.The defect of atrial septum is mainly formed in the life of fetus
During long development, due to being affected the development of heart by certain factor, to form atrial septal defect.For atrial septal defect
For patient, since the pressure of atrium sinistrum is higher than atrium dextrum, and the part blood of atrium sinistrum is made to flow to the right heart through atrial septal defect
Room causes the right burden for feeling concerned about system to increase, and causes right ventricular hypertrophy, and pulmonary circulatory blood volume increases, the long-term existence of atrial septal defect
It will cause the illnesss such as pulmonary hypertension, congestive heart failure, arrhythmia cordis, apoplexy, dizziness, faintness.
Surgical operation is to treat the conventional method of atrial septal defect, however, surgical operation therapy atrial septal defect needs are opened
Chest has the disadvantages that in operation and needs extracorporal circulatory system, may cause complication and lead to death；Wound is big, and in body surface
Leave the scar of operative incision；Surgery cost is high simultaneously.In order to avoid carrying out open chest surgery to patients with atrial septal defect, early in
Nineteen sixties medical investigator has just carried out the discussion of non-surgery operation method treatment atrial septal defect, successively invents
A variety of plugging devices such as Rishkind, Sideris and Amplatzer plugging devices are sent into plugging device through cardiac catheter and are closed room
Every defect, reach with the comparable curative effect of surgery open chest surgery, and can to avoid blood transfusion and as caused by blood transfusion and surgical operation
Complication.However clinical application find that, Rishkind and Sideris plugging device success rate is low and the incidence of complication is high,
It is gradually eliminated, clinically most widely used in recent years is Amplatzer plugging device, is in double plate piece eel-like figure shape structure, tool
There is fixed waist size, it tends to be difficult to there is residual leakage with postoperative so as to cause in art in " soft-sided " of clamping atrial septal defect,
So that echocardiography in atrial septal defect failure or dysraphism, at the same the design of this standardized plugging device be difficult to meet it is complicated and changeable
Atrial septum anatomic form and also easily there is complication.As for its developed to adapt to the atrial septal defect of different anatomic form
His plugging device then haves the defects that model is complicated, is not easy to produce and use and increase operative complications.So needing to research and develop
A kind of production and using simple and can be avoided in art and the postoperative novel stopper for residual leakage phenomenon occur out.
Summary of the invention
In view of the above problems, inventor furthers investigate and analyzes to atrial septal defect, and constantly carries out real
It tests, develops a kind of Novel room every defect plugging device, structure is simple, can adapt to the atrial septal defect of different anatomic form
And it is not easy in art residual leakage phenomenon occur with postoperative.
To achieve the goals above, the present invention provides a kind of Novel room every defect plugging device comprising thin-film barrier layers,
First support body, second support body, the first fixedly connected part and the second fixedly connected part, which is characterized in that first support body and
Second support body is woven by the Memorability metal alloy wires of compressible deformation, wherein the Memorability metal in first support body
The both ends of alloy wire are respectively fixedly connected with the front end in the first fixedly connected part and the front end of the second fixedly connected part, second support
The both ends of Memorability metal alloy wires in body, which are respectively fixedly connected with, to be fixedly connected in the rear end of the first fixedly connected part with second
The rear end of part；First fixedly connected part and the second fixedly connected part are cylindrical-shaped structure and the front end of the first fixedly connected part and the
The rear end of two fixedly connected parts is equipped with internal screw thread to connect transportation system；Thin-film barrier layers are built into first support body and second
In support body.
In Novel room of the invention every in defect plugging device, the model of the internal screw thread and the hand for the treatment of atrial septal defect
The model of the helicitic texture of the transportation system of conveying plugging device of the present invention matches when art, and the transportation system can be this field
In conventional use of plugging device conveying device.
When operation, now Novel room of the invention is connected every defect plugging device with transportation system, passes through transportation system
Plugging device is delivered at atrial septal defect, because of the characteristic of Memorability metal alloy, first support body and second support body are replied
The edge of atrial septal defect is clamped to preset shape, then closed room discharges plugging device every defect, terminates operation.This
The Novel room of invention, due to forming biggish clamping force between first support body and second support body, and is kept away every defect plugging device
Residual leakage is exempted from, improving existing plugging device can not clamping atrial septal defect edge due to having fixed waist structure.
Preferably, in Novel room of the invention every in defect plugging device, first fixedly connected part and second is fixed
The length of connector is 1mm-3mm, preferably 1mm-2mm.If the length of the first fixedly connected part and the second fixedly connected part is spent
Small, then its internal internal screw thread circle number is very few, can cause to be not connected firmly with transportation system and in art there are plugging device with it is defeated
Send the risk that system falls off；, whereas if the length of the first fixedly connected part and the second fixedly connected part is excessive, then it will increase envelope
The risk that stifled device surface local thrombus is formed, and easily lead to first support body and the when second support body restores to preset shape
The distance between one fixedly connected part and the second fixedly connected part are too small, influence first support body and second support body clamps room
Every the soft-sided of defect.
Preferably, in Novel room of the invention every in defect plugging device, first fixedly connected part and second is fixed
The internal diameter of connector is 1-2mm, if the internal diameter of the first fixedly connected part and the second fixedly connected part is too small, the plugging device
Being not connected firmly between fixed link is leaned on；, whereas if the internal diameter of the first fixedly connected part and the second fixedly connected part is excessive, meeting
It is oversized after causing plugging device to fold gathering.
Preferably, in Novel room of the invention every in defect plugging device, the thin-film barrier layers by biocompatibility compared with
Good high material composition, such as polylactic acid, polyglycolic acid and polyanhydride.The thin-film barrier layers are by the preferable high score of biocompatibility
Sub- material composition can significantly improve the biocompatibility of plugging device.
It is highly preferred that the thin-film barrier layers are in homogeneous thickness in Novel room of the invention every in defect plugging device
Biomembrane, with a thickness of 0.1mm-0.2mm.If the thickness of thin-film barrier layers is too small, thin-film barrier layers are easy to because of blood
The impact force of stream and rupture；, whereas if the thickness of thin-film barrier layers is too big, then the weight of thin-film barrier layers increases, and causes to seal
The weight of stifled device also increases, and is unfavorable for closed room every defect.
Preferably, in Novel room of the invention every in defect plugging device, the first support body and second support body
Preset shape is the lantern-shaped of intermediate projections.In use, since Memorability metal alloy persistently returns modeling, first support body and second
Support body restores to preset lantern-shaped, since the first support body and second support body of lantern-shaped form biggish clamping
Power and so that entire plugging device is preferably clamped atrial septal defect edge, closed room is every defect.
It is highly preferred that in Novel room of the invention every in defect plugging device, the first support body and second support body
Longitudinal section when restoring to the lantern-shaped of intermediate projections at the intermediate projections of the lantern-shaped of intermediate projections is circle, and a diameter of
5mm-50mm.Novel room of the invention can be according to by under the cooperation of X-ray, angiography and color ultrasound every defect plugging device
And the size for the atrial septal defect estimated in advance and select the first support body and second support body of suitable size, with preferably real
The perfect cooperation of existing plugging device and atrial septal defect.
Preferably, in Novel room of the invention every in defect plugging device, in the first support body and second support body
The quantity of Memorability metal alloy wires be 20-30.If the Memorability metal in first support body and second support body closes
The number of spun gold is very little, then first support body and second support body can not form the side that enough clamping forces clamp atrial septal defect
, every defect, easily there is obscission with closed room in edge；, whereas if the Memorability gold in first support body and second support body
The number for belonging to alloy wire is too many, then the weight of plugging device can then dramatically increase, and equally will increase the risk to fall off.
Preferably, in Novel room of the invention every in defect plugging device, in the first support body and second support body
Memorability metal alloy wires diameter be 0.1-0.2mm.If the Memorability metal in first support body and second support body
The diameter of alloy wire is too small, then first support body and second support body due to Memorability metal alloy wires it is too thin and intensity is too small,
Also without enough support forces, so that the easy shape of entire plugging device；, whereas if the memory in first support body and second support body
The diameter of property metal alloy wires is too big, then the weight of plugging device can then dramatically increase, and will increase the risk to fall off.
Preferably, in Novel room of the invention every in defect plugging device, the first support body and second support body pressure
Shape after contracting is tubular dictyosome structure, which can easily get at atrial septal defect very much when in use.
Preferably, in Novel room of the invention every in defect plugging device, first fixedly connected part, the second fixation connect
Fitting, first support body and second support body surface face are coated with carbon thin film layer, to improve the anti-corrosion effect of entire plugging device simultaneously
It prevents metal ion from entering blood, the formation of thrombus is effectively controlled, so that using safer.
In Novel room of the invention every in defect plugging device, the thin-film barrier layers attach respectively first support body and/
Or on the wire of second support body, to be clamped in the space that the wire of first support body and/or second support body surrounds.
Novel room of the invention provides closed room every the new approaches of defect every defect plugging device, using plugging device it
Between clamping force effectively clamp the edge of atrial septal defect, rather than have fixed waist size logical as existing plugging device
The edge of clamping atrial septal defect and closed room are crossed every defect.
It should be noted that in the present invention, " first " and " second " does not represent specific quantity and sequence, only
For the differentiation to title.
Compared with prior art, the invention has the advantages that and advantage:
(1) Novel room of the invention has technical progress every defect plugging device, is that the unprecedented innovation of one kind is set
Meter；And unique structure is even more to be compared far from existing plugging device, while sound construction, form are reasonable, elasticity is appropriate, implantation
Convenient, positioning is easy, and is very suitable to standardized production and large-scale application；
(2) Novel room of the invention provides closed room every the new approaches of defect every defect plugging device, utilizes first
Biggish clamping force closed room is formed between support body and second support body every defect, and avoids residual leakage, is improved existing
There is plugging device can not clamping atrial septal defect edge due to having fixed waist structure；
(3) Novel room of the invention can be according to passing through the cooperation in X-ray, angiography and color ultrasound every defect plugging device
The lower and size of atrial septal defect estimated in advance and the first support body and second support body that select suitable size, with preferably
The cooperation for realizing plugging device and atrial septal defect, is not in that model is not inconsistent, plugging device size is significantly greater than atrial septal defect
Phenomenon avoids waste of material, to reduce costs.
Detailed description of the invention
The drawings are intended to provide a further understanding of the invention, and constitutes part of specification, with following tool
Body embodiment is used to explain the present invention together, but is not construed as limiting the invention.
Fig. 1 is Novel room of the invention every the structural schematic diagram under defect plugging device compressive state；
Fig. 2 is structural schematic diagram of the Novel room under the compressive state in Fig. 1 every another visual angle of defect plugging device；
Fig. 3 is structural schematic diagram of the Novel room after defect plugging device restores shape in Fig. 1；
Fig. 4 is structural schematic diagram of the Novel room in Fig. 1 every another visual angle of defect plugging device recovery shape.
Appended drawing reference:
1 first fixedly connected part；
2 second fixedly connected parts；
3 first support bodies；
4 second support bodies；
5 internal screw threads；
6 Memorability metal alloy wires.
Specific embodiment
It, will be referring to the attached drawing for constituting this specification a part in specific embodiment below.Without departing from opening up herein
It is illustrated of the invention in substantially describe herein and attached drawing in the case where the principle and range of the subject matter shown
Various aspects can be arranged in wide in range configuration variation, replaced, combined and be decoupled, it is all these arrangement, replacement, combination and
Partition is each fallen within the scope of the present invention.
It should be noted that in the description of this specification, the orientation or positional relationship of the instructions such as term "front", "rear" is
It is based on the orientation or positional relationship shown in the drawings, is merely for convenience of description of the present invention and simplification of the description, rather than instruction or dark
Show that signified device or unit there must be specific direction, be constructed and operated in a specific orientation, it is thus impossible to be interpreted as pair
Limitation of the invention.
Unless otherwise defined, all technical and scientific terms used herein and belong to technical field of the invention
The normally understood meaning of technical staff is identical.Term as used herein in the specification of the present invention is intended merely to description tool
The purpose of the embodiment of body, it is not intended that invented in limitation.
Specific embodiments of the present invention will be further explained with reference to the accompanying drawings and detailed description.
Fig. 1 is Novel room of the invention every the structural schematic diagram under defect plugging device compressive state, and Fig. 2 is in Fig. 1
For Novel room under compressive state every the structural schematic diagram at another visual angle of defect plugging device, Fig. 3 is Novel room of the invention
Structural schematic diagram after defect plugging device restores shape, Fig. 4 are that the atrial septal defect plugging device in Fig. 3 restores the another of shape
The structural schematic diagram at visual angle.In conjunction with Fig. 1-4 it is found that Novel room of the invention every defect plugging device includes first support body 3,
Two support bodies 4, the first fixedly connected part 1 and the second fixedly connected part 2, wherein first support body 3 and second support body 4 are by that can press
The Memorability metal alloy wires 6 of compression deformation weave, wherein the both ends of the Memorability metal alloy wires 6 in first support body 3
It is respectively fixedly connected with the front end in the first fixedly connected part 1 and the front end of the second fixedly connected part 2, the note in second support body 4
The both ends of the property recalled metal alloy wires 6 are respectively fixedly connected with behind the rear end of the first fixedly connected part 1 and the second fixedly connected part 2
End, i.e. one end of Memorability metal alloy wires 6 in first support body 3 are fixedly connected on the front end of the first fixedly connected part 1, and
The other end is fixedly connected on the front end of the second fixedly connected part 2, one end of the Memorability metal alloy wires 6 in second support body 4
It is fixedly connected on the rear end of the first fixedly connected part 1, and the other end is fixedly connected on the rear end of the second fixedly connected part 2；First
Front end of the fixedly connected part 1 with the second fixedly connected part 2 for cylindrical-shaped structure and the first fixedly connected part 1 is fixedly connected with second
The rear end of part 2 is equipped with internal screw thread 5 to connect transportation system, and internal screw thread 5 is set to the first fixedly connected part 1 in the present embodiment
Front end and the second fixedly connected part 2 rear end；However plugging device of the present invention further includes thin-film barrier layers but is not shown in the figure,
Middle thin-film barrier layers are built into first support body 3 and second support body 4.
The first support body 3 and the compressed shape of second support body 4 are tubular dictyosome structure, and entire plugging device is made to exist
It is cylindric under compressive state.The structure can be easily got at atrial septal defect very much when in use.
The preset shape of the first support body 3 and second support body 4 is the lantern-shaped of intermediate projections.In use, due to
Memorability metal alloy persistently returns modeling, and first support body 3 and second support body 4 restore to preset lantern-shaped, due to lamp
The first support body 3 and second support body 4 of caged form biggish clamping force and entire plugging device are enable preferably to clamp room
Septal defect edge, closed room is every defect.
Memorability metal alloy wires 6 in the first support body 3 and second support body 4 are 25, but its Memorability
The quantity of metal alloy wires 6 can be also other numbers, preferably within the scope of 20-30.If first support body 3 and second support
The number of Memorability metal alloy wires in body 4 is very little, then first support body 3 and second support body 4 can not form enough folders
, every defect, easily there is obscission with closed room in the edge of clamp force clamping atrial septal defect；, whereas if first support body 3
Too many with the number of the Memorability metal alloy wires in second support body 4, then the weight of plugging device can then dramatically increase, same meeting
Increase the risk to fall off.In addition, in order to obtain preferable clamping force so that atrial septal defect, the first support can be completely enclosed
It is solid that Memorability metal alloy wires 6 in body 3 and second support body 4 are equably fixedly connected on the first fixedly connected part 1 and second
Determine on connector 2.
The lantern-shaped of intermediate projections when the first support body 3 and second support body 4 restore to the lantern-shaped of intermediate projections
Intermediate projections at longitudinal section be circle, and a diameter of 5mm-50mm.Novel room of the invention is big every defect plugging device
It is small in a relatively wide in range range, can be according to estimating in advance and under the cooperation in X-ray, angiography and color ultrasound
The size of atrial septal defect and the first support body 3 and second support body 4 for selecting suitable size, be better achieved plugging device with
The perfect cooperation of atrial septal defect.
In addition, the diameter of the Memorability metal alloy wires 6 in the first support body 3 and second support body 4 is 0.1-
0.2mm.If the diameter of the Memorability metal alloy wires 6 in first support body 3 and second support body 4 is too small, first support
Body 3 and second support body 4 are since Memorability metal alloy wires 6 are too thin and intensity is too small, also without enough support forces, so that whole
A easy shape of plugging device；, whereas if the diameter of the Memorability metal alloy wires 6 in first support body 3 and second support body 4 is too
Greatly, then the weight of plugging device can then dramatically increase, and will increase the risk to fall off.
In addition, first fixedly connected part 1,4 surface of the second fixedly connected part 2, first support body 3 and second support body
It is coated with carbon thin film layer, to improve the anti-corrosion effect of entire plugging device and prevent metal ion from entering blood, effectively controls blood
The formation of bolt, so that using safer.
Except, the length of first fixedly connected part 1 and the second fixedly connected part 2 is 1mm-3mm, preferably 1mm-2mm.
If the length of the first fixedly connected part 1 and the second fixedly connected part 2 is too small, the internal circle number of internal screw thread 5 is very few, can draw
It rises and is not connected firmly and there are the risks that plugging device and transportation system fall off in art with transportation system；, whereas if first is solid
The length for determining connector 1 and the second fixedly connected part 2 is excessive, then will increase the risk of plugging device surface local thrombus formation, and
And it easily leads to first support body 3 and is fixedly connected with the first fixedly connected part 1 when the recovery of second support body 4 to preset shape with second
The distance between part 2 is too small, influences first support body 3 and second support body 4 clamps the soft-sided of atrial septal defect.
Also, the internal diameter of first fixedly connected part 1 and the second fixedly connected part 2 is 1mm-2mm, if first is fixed
Connector 1 and the internal diameter of the second fixedly connected part 2 are too small, then being not connected firmly between the plugging device and fixed link is leaned on；Conversely,
If the internal diameter of the first fixedly connected part 1 and the second fixedly connected part 2 is excessive, it will lead to plugging device and fold size mistake after gathering
Greatly.
About the thin-film barrier layers, be made of the preferably high material of biocompatibility, as polylactic acid, polyglycolic acid and
Polyanhydride.The thin-film barrier layers are made of the biology that can significantly improve plugging device the preferable high molecular material of biocompatibility
Compatibility.
In addition, the thin-film barrier layers are biomembrane in homogeneous thickness, with a thickness of 0.1mm-0.2mm.If film hinders
The thickness of interlayer is too small, then thin-film barrier layers are easy to rupture because of the impact force of blood flow；, whereas if thin-film barrier layers
Thickness is too big, then the weight of thin-film barrier layers increases, and causes the weight of plugging device also to increase, is unfavorable for closed room every defect.
When operation, now Novel room of the invention is connected every defect plugging device with transportation system, passes through transportation system
Plugging device is delivered at atrial septal defect, because of the characteristic of Memorability metal alloy, first support body and second support body are replied
The edge of atrial septal defect is clamped to preset shape, then closed room discharges plugging device every defect, terminates operation.
According to the disclosure and teachings of the above specification, those skilled in the art in the invention can also be to above-mentioned embodiment party
Formula is changed and is modified.Therefore, the invention is not limited to the specific embodiments disclosed and described above, to the one of invention
A little modifications and changes should also be as falling into the scope of the claims of the present invention.In addition, although being used in this specification
Some specific terms, these terms are merely for convenience of description, does not limit the present invention in any way.
Claims (9)
1. a kind of Novel room is every defect plugging device comprising thin-film barrier layers, first support body, second support body, first are consolidated
Determine connector and the second fixedly connected part, which is characterized in that first support body and second support body by compressible deformation memory
Property metal alloy wires weave, and wherein the both ends of the Memorability metal alloy wires in first support body are respectively fixedly connected in
The front end of the front end of one fixedly connected part and the second fixedly connected part, the both ends of the Memorability metal alloy wires in second support body
It is respectively fixedly connected with the rear end in the first fixedly connected part and the rear end of the second fixedly connected part；First fixedly connected part and second
Fixedly connected part is cylindrical-shaped structure and the front end of the first fixedly connected part and the rear end of the second fixedly connected part are equipped with internal screw thread
To connect transportation system, the length of the first fixedly connected part and the second fixedly connected part is 1mm-3mm, and a diameter of 1mm-
2mm；Thin-film barrier layers are built into first support body and second support body.
2. Novel room according to claim 1 is every defect plugging device, which is characterized in that first fixedly connected part and
The length of second fixedly connected part is 1mm-2mm.
3. Novel room according to claim 1 is every defect plugging device, which is characterized in that the thin-film barrier layers are thickness
Uniform biomembrane, with a thickness of 0.1mm-0.2mm.
4. Novel room according to claim 1 is every defect plugging device, which is characterized in that the first support body and
The preset shape of second support body is the lantern-shaped of intermediate projections.
5. Novel room according to claim 4 is every defect plugging device, which is characterized in that the first support body and second
Longitudinal section when support body restores to the lantern-shaped of intermediate projections at the intermediate projections of the lantern-shaped of intermediate projections is circle, and its
Diameter is 5mm-50mm.
6. Novel room according to any one of claims 1-5 is every defect plugging device, which is characterized in that described first
The quantity of Memorability metal alloy wires in frame body and second support body is 20-30.
7. Novel room according to any one of claims 1-5 is every defect plugging device, which is characterized in that described first
The diameter of Memorability metal alloy wires in frame body and second support body is 0.1-0.2mm.
8. Novel room according to any one of claims 1-5 is every defect plugging device, which is characterized in that described first is solid
Determine connector, the second fixedly connected part, first support body and second support body surface face and is coated with carbon thin film layer.
9. Novel room according to any one of claims 1-5 is every defect plugging device, which is characterized in that described first
Frame body and the compressed shape of second support body are tubular dictyosome structure.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710159779.5A CN106821427B (en) | 2017-03-17 | 2017-03-17 | A kind of Novel room is every defect plugging device |
| PCT/CN2018/078145 WO2018166377A1 (en) | 2017-03-17 | 2018-03-06 | New occluding device for septal defect |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710159779.5A CN106821427B (en) | 2017-03-17 | 2017-03-17 | A kind of Novel room is every defect plugging device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106821427A CN106821427A (en) | 2017-06-13 |
| CN106821427B true CN106821427B (en) | 2019-09-20 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710159779.5A Expired - Fee Related CN106821427B (en) | 2017-03-17 | 2017-03-17 | A kind of Novel room is every defect plugging device |
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| Country | Link |
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| CN (1) | CN106821427B (en) |
| WO (1) | WO2018166377A1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106821427B (en) * | 2017-03-17 | 2019-09-20 | 广州新诚生物科技有限公司 | A kind of Novel room is every defect plugging device |
| CN109758194B (en) * | 2019-02-27 | 2020-06-26 | 武汉唯柯医疗科技有限公司 | Atrial septum plugging device |
| CN114224402A (en) * | 2020-09-09 | 2022-03-25 | 江苏朴芃医疗科技有限公司 | Plugging device |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101450013A (en) * | 2007-11-28 | 2009-06-10 | 王涛 | Blocking device of heart atrial, ventricular septal defect and patent oval foramen |
| CN207323503U (en) * | 2017-03-17 | 2018-05-08 | 广州新诚生物科技有限公司 | A kind of Novel room is every defect plugging device |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8366741B2 (en) * | 2007-09-13 | 2013-02-05 | Cardia, Inc. | Occlusion device with centering arm |
| CN101449986B (en) * | 2007-11-28 | 2011-08-31 | 王涛 | Obturator of aorta ductus arteriosus |
| CN106821427B (en) * | 2017-03-17 | 2019-09-20 | 广州新诚生物科技有限公司 | A kind of Novel room is every defect plugging device |
-
2017
- 2017-03-17 CN CN201710159779.5A patent/CN106821427B/en not_active Expired - Fee Related
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2018
- 2018-03-06 WO PCT/CN2018/078145 patent/WO2018166377A1/en active Application Filing
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101450013A (en) * | 2007-11-28 | 2009-06-10 | 王涛 | Blocking device of heart atrial, ventricular septal defect and patent oval foramen |
| CN207323503U (en) * | 2017-03-17 | 2018-05-08 | 广州新诚生物科技有限公司 | A kind of Novel room is every defect plugging device |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106821427A (en) | 2017-06-13 |
| WO2018166377A1 (en) | 2018-09-20 |
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