CN106821427A - A kind of Novel room is every defect plugging device - Google Patents
A kind of Novel room is every defect plugging device Download PDFInfo
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- CN106821427A CN106821427A CN201710159779.5A CN201710159779A CN106821427A CN 106821427 A CN106821427 A CN 106821427A CN 201710159779 A CN201710159779 A CN 201710159779A CN 106821427 A CN106821427 A CN 106821427A
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- support body
- fixedly connected
- plugging device
- connected part
- defect
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- 230000007547 defect Effects 0.000 title claims abstract description 63
- 239000010409 thin film Substances 0.000 claims abstract description 25
- 230000004888 barrier function Effects 0.000 claims abstract description 22
- 229910001092 metal group alloy Inorganic materials 0.000 claims description 30
- 230000006698 induction Effects 0.000 claims description 12
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 3
- 238000009954 braiding Methods 0.000 claims description 3
- 229910052799 carbon Inorganic materials 0.000 claims description 3
- 230000006835 compression Effects 0.000 claims description 3
- 238000007906 compression Methods 0.000 claims description 3
- 208000035478 Interatrial communication Diseases 0.000 abstract description 40
- 208000013914 atrial heart septal defect Diseases 0.000 abstract description 40
- 206010003664 atrial septal defect Diseases 0.000 abstract description 40
- 238000013459 approach Methods 0.000 abstract description 3
- 239000010410 layer Substances 0.000 description 20
- 239000008280 blood Substances 0.000 description 8
- 210000004369 blood Anatomy 0.000 description 8
- 210000002837 heart atrium Anatomy 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 238000001356 surgical procedure Methods 0.000 description 5
- 230000000007 visual effect Effects 0.000 description 4
- 229910000521 B alloy Inorganic materials 0.000 description 3
- 208000007536 Thrombosis Diseases 0.000 description 3
- 238000002583 angiography Methods 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 229910052751 metal Inorganic materials 0.000 description 3
- 230000002980 postoperative effect Effects 0.000 description 3
- 238000002604 ultrasonography Methods 0.000 description 3
- 229920000954 Polyglycolide Polymers 0.000 description 2
- 230000002421 anti-septic effect Effects 0.000 description 2
- 210000003157 atrial septum Anatomy 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 208000002173 dizziness Diseases 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 2
- 239000010931 gold Substances 0.000 description 2
- 229910052737 gold Inorganic materials 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 229910021645 metal ion Inorganic materials 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000004633 polyglycolic acid Substances 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 206010007559 Cardiac failure congestive Diseases 0.000 description 1
- 206010008190 Cerebrovascular accident Diseases 0.000 description 1
- 208000002330 Congenital Heart Defects Diseases 0.000 description 1
- 206010019280 Heart failures Diseases 0.000 description 1
- 208000000924 Right ventricular hypertrophy Diseases 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- 206010003119 arrhythmia Diseases 0.000 description 1
- 230000006793 arrhythmia Effects 0.000 description 1
- 230000000747 cardiac effect Effects 0.000 description 1
- 208000028831 congenital heart disease Diseases 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 238000002592 echocardiography Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 210000003754 fetus Anatomy 0.000 description 1
- 239000010408 film Substances 0.000 description 1
- 208000025339 heart septal defect Diseases 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 239000011229 interlayer Substances 0.000 description 1
- 210000005246 left atrium Anatomy 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000005192 partition Methods 0.000 description 1
- 230000002685 pulmonary effect Effects 0.000 description 1
- 208000002815 pulmonary hypertension Diseases 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
- A61B2017/00588—Rigid or stiff implements, e.g. made of several rigid parts linked by hinges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
- A61B2017/00601—Implements entirely comprised between the two sides of the opening
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
- A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
- A61B2017/00606—Implements H-shaped in cross-section, i.e. with occluders on both sides of the opening
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00867—Material properties shape memory effect
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- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
- Prostheses (AREA)
Abstract
The invention discloses a kind of Novel room every defect plugging device, it includes thin-film barrier layers, first support body, second support body, the first fixedly connected part and the second fixedly connected part.Novel room of the invention provides new approaches of the closed room every defect every defect plugging device, effectively clamp the edge of atrial septal defect using the clamping force between plugging device, rather than have as existing plugging device fixed waist size by the edge of clamping atrial septal defect closed room every defect.
Description
Technical field
The present invention relates to technical field of medical instruments, particularly a kind of Novel room is every defect plugging device.
Background technology
Atrial septal defect is a kind of clinically common congenital heart disease, and lesion characteristic is the room between left atrium
Interval fails normally closed, and blood flows between atrium sinistrum and atrium dextrum.The defect of atrial septum is mainly formed in the life of fetus
During development long, developed due to have impact on heart by certain factor, so as to form atrial septal defect.For atrial septal defect
For patient, because the pressure of atrium sinistrum is higher than atrium dextrum, and the part blood of atrium sinistrum is set to flow to the right heart through atrial septal defect
Room, causes the right burden for feeling concerned about system to increase, and causes right ventricular hypertrophy, pulmonary circulatory blood volume to increase, the long-term existence of atrial septal defect
The illnesss such as pulmonary hypertension, congestive heart failure, arrhythmia cordis, apoplexy, dizziness, faintness can be caused.
Surgical operation is the conventional method for treating atrial septal defect, however, surgical operation therapy atrial septal defect needs to open
Chest, it has the disadvantages that：Extracorporal circulatory system is needed in operation, complication is likely to result in and is caused death；Wound is big, and in body surface
Leave the scar of operative incision；Surgery cost is high simultaneously.In order to avoid carrying out open chest surgery to patients with atrial septal defect, early in
Nineteen sixties medical investigator has just carried out the discussion that non-surgery operation method treats atrial septal defect, successively invents
Various plugging devices such as Rishkind, Sideris and Amplatzer plugging devices, through cardiac catheter feeding plugging device closure room
Every defect, the curative effect suitable with surgery open chest surgery is reached, and can avoid what is transfused blood and caused by blood transfusion and surgical operation
Complication.But clinical application find that, Rishkind and Sideris plugging device success rates are low and incidence of complication is high,
Gradually it is eliminated, clinically most widely used in recent years is Amplatzer plugging devices, it is in double plate piece eel-like figure shape structure, has
There is fixed waist size, it tends to be difficult to " soft-sided " of clamping atrial septal defect, so as to cause residual leakage occur with postoperative in art,
So that echocardiography in atrial septal defect failure or dysraphism, while this standardized plugging device design is difficult to meet complicated and changeable
Atrial septum anatomic form and also easily there is complication.As for developed to adapt to the atrial septal defect of different anatomic form its
His plugging device then has the defect that model is complicated, be not easy to produce and use and increase operative complications.So need research and development
Go out a kind of production and using simple and can avoid in art and the postoperative novel stopper for residual leakage phenomenon occur.
The content of the invention
In view of the above problems, inventor is furtherd investigate and is analyzed to atrial septal defect, and constantly carries out reality
Test, develop a kind of Novel room every defect plugging device, its simple structure can adapt to the atrial septal defect of different anatomic form
And it is difficult in art residual leakage phenomenon occur with postoperative.
To achieve these goals, the present invention provides a kind of Novel room every defect plugging device, it include thin-film barrier layers,
First support body, second support body, the first fixedly connected part and the second fixedly connected part, it is characterised in that first support body and
Second support body is formed by the Memorability metal alloy wires braiding of compressible deformation, wherein the Memorability metal in first support body
The two ends of B alloy wire are respectively fixedly connected with the front end of the front end of the first fixedly connected part and the second fixedly connected part, second support
The two ends of the Memorability metal alloy wires in body are respectively fixedly connected with and are fixedly connected with second in the rear end of the first fixedly connected part
The rear end of part；First fixedly connected part and the second fixedly connected part are cylindrical-shaped structure and the front end of the first fixedly connected part and the
The rear end of two fixedly connected parts is provided with internal thread and is used to connect induction system；Thin-film barrier layers are built into first support body and second
In stake body.
In Novel room of the invention every in defect plugging device, the model of the internal thread and the hand for the treatment of atrial septal defect
The model that the helicitic texture of the induction system of plugging device of the present invention is conveyed during art matches, and the induction system can be this area
In conventional use of plugging device conveying device.
During operation, now Novel room of the invention is connected every defect plugging device with induction system, by induction system
Plugging device is delivered at atrial septal defect, because of the characteristic of Memorability metal alloy, first support body and second support body are replied
To default shape to clamp the edge of atrial septal defect, then closed room discharges plugging device every defect, terminates operation.This
The Novel room of invention, due to forming larger clamping force between first support body and second support body, and is kept away every defect plugging device
Exempt from residual leakage, improve existing plugging device due to cannot clamping atrial septal defect edge with fixed waist structure.
Preferably, in Novel room of the invention every in defect plugging device, first fixedly connected part and second is fixed
The length of connector is 1mm-3mm, preferably 1mm-2mm.If the length of the first fixedly connected part and the second fixedly connected part is spent
Small, then its internal internal thread number of turns is very few, can cause be connected with induction system it is insecure and exist in art plugging device with it is defeated
Send the risk that system comes off；, whereas if the length of the first fixedly connected part and the second fixedly connected part is excessive, then can increase envelope
The risk that stifled device surface local thrombus are formed, and it is easily caused first support body and second support body recovers to during preset shape the
The distance between one fixedly connected part and the second fixedly connected part are too small, and influence first support body and second support body clamp room
Every the soft-sided of defect.
Preferably, in Novel room of the invention every in defect plugging device, first fixedly connected part and second is fixed
The internal diameter of connector is 1-2mm, if the internal diameter of the first fixedly connected part and the second fixedly connected part is too small, the plugging device
Connection between fix bar is not firm；, whereas if the internal diameter of the first fixedly connected part and the second fixedly connected part is excessive, meeting
Cause plugging device folding oversized after drawing in.
Preferably, in Novel room of the invention every in defect plugging device, the thin-film barrier layers by biocompatibility compared with
Good material high composition, such as PLA, polyglycolic acid and condensing model.The thin-film barrier layers are by the preferable high score of biocompatibility
Sub- material composition can significantly improve the biocompatibility of plugging device.
It is highly preferred that in Novel room of the invention every in defect plugging device, the thin-film barrier layers are in uniform thickness
Biomembrane, its thickness is 0.1mm-0.2mm.If the thickness of thin-film barrier layers is too small, thin-film barrier layers are easy to because blood
The impulsive force of stream and rupture；, whereas if the thickness of thin-film barrier layers is too big, then the weight of thin-film barrier layers is increased, and causes envelope
The weight of stifled device is also increased, and is unfavorable for closed room every defect.
Preferably, in Novel room of the invention every in defect plugging device, the first support body and second support body
Preset shape is the lantern-shaped of intermediate projections.When using, because Memorability metal alloy persistently returns modeling, first support body and second
Stake body recovers to lantern-shaped set in advance, because the first support body and second support body of lantern-shaped form larger clamping
Power and whole plugging device is preferably clamped atrial septal defect edge, closed room is every defect.
It is highly preferred that in Novel room of the invention every in defect plugging device, the first support body and second support body
The longitudinal section recovered during the lantern-shaped to intermediate projections at the intermediate projections of the lantern-shaped of intermediate projections is circle, and its is a diameter of
5mm-50mm.Novel room of the invention can be according to by under the cooperation of X-ray, angiography and color ultrasound every defect plugging device
And the size of the atrial septal defect estimated in advance and select the first support body and second support body of suitable size, with preferably real
The perfect cooperation of existing plugging device and atrial septal defect.
Preferably, in Novel room of the invention every in defect plugging device, in the first support body and second support body
The quantity of Memorability metal alloy wires be 20-30.If the Memorability metal in first support body and second support body is closed
Very little, then first support body and second support body cannot form the side that enough clamping forces clamp atrial septal defect to the number of spun gold
, every defect, easily there is obscission with closed room in edge；, whereas if the Memorability gold in first support body and second support body
The number for belonging to B alloy wire is too many, then the weight of plugging device can then be dramatically increased, and can equally increase the risk for coming off.
Preferably, in Novel room of the invention every in defect plugging device, in the first support body and second support body
Memorability metal alloy wires a diameter of 0.1-0.2mm.If the Memorability metal in first support body and second support body
The diameter of B alloy wire is too small, then first support body and second support body due to Memorability metal alloy wires it is too thin and intensity is too small,
Also without enough support forces, so that the easy shape of whole plugging device；, whereas if the memory in first support body and second support body
The diameter of property metal alloy wires is too big, then the weight of plugging device can then be dramatically increased, and can increase the risk for coming off.
Preferably, in Novel room of the invention every in defect plugging device, the first support body and second support body pressure
Tubular dictyosome structure is shaped as after contracting, the structure can be easily got at atrial septal defect very much when in use.
Preferably, in Novel room of the invention every in defect plugging device, first fixedly connected part, the second fixation connect
Fitting, first support body and second support body surface face are coated with carbon thin film layer, so as to improve whole plugging device antiseptic effect simultaneously
Prevent metal ion from entering blood, effectively the formation of control thrombus, so that using safer.
In Novel room of the invention every in defect plugging device, the thin-film barrier layers attach respectively first support body and/
Or on the wire of second support body, to be clamped in the space that the wire of first support body and/or second support body is surrounded.
Novel room of the invention every defect plugging device provide closed room every defect new approaches, using plugging device it
Between clamping force effectively clamp the edge of atrial septal defect, rather than there is fixed waist size to lead to as existing plugging device
Cross clamping atrial septal defect edge and closed room every defect.
It should be noted that in the present invention, " first " and " second " does not represent specific quantity and order, only
For the differentiation to title.
Compared with prior art, the invention has the advantages that and advantage：
(1) Novel room of the invention has technological progress every defect plugging device, is that a kind of unprecedented innovation sets
Meter；And the structure of uniqueness is more far from what existing plugging device was compared, while sound construction, form are reasonable, elasticity is appropriate, implantation
Convenient, positioning is easy, is especially suitable for standardized production and large-scale application；
(2) Novel room of the invention provides new approaches of the closed room every defect every defect plugging device, using first
Larger clamping force closed room is formed between stake body and second support body every defect, and avoids residual leakage, improved existing
There is plugging device due to cannot clamping atrial septal defect edge with fixed waist structure；
(3) Novel room of the invention can be according to by the cooperation in X-ray, angiography and color ultrasound every defect plugging device
The lower and size of atrial septal defect estimated in advance and the first support body and second support body that select suitable size, with preferably
The cooperation of plugging device and atrial septal defect is realized, is not in that model is not inconsistent, plugging device size is significantly greater than atrial septal defect
Phenomenon, it is to avoid waste of material, so as to reducing cost.
Brief description of the drawings
Accompanying drawing is, for providing a further understanding of the present invention, and to constitute the part of specification, with following tool
Body implementation method is used to explain the present invention together, but is not construed as limiting the invention.
Fig. 1 is Novel room of the invention every the structural representation under defect plugging device compressive state；
Fig. 2 is structural representation of the Novel room under the compressive state in Fig. 1 every another visual angle of defect plugging device；
Structural representations of the Fig. 3 for the Novel room in Fig. 1 after defect plugging device recovers shape；
Fig. 4 is structural representation of the Novel room in Fig. 1 every another visual angle of defect plugging device recovery shape.
Reference：
1 first fixedly connected part；
2 second fixedly connected parts；
3 first support bodies；
4 second support bodies；
5 internal threads；
6 Memorability metal alloy wires.
Specific embodiment
In specific embodiment below, by with reference to the accompanying drawing for constituting this specification part.Without departing from opening up herein
It is illustrated of the invention in substantially describe herein and accompanying drawing in the case of the principle and scope of the subject matter shown
Each side can be arranged in wide in range configuration variation, replaced, combined and decoupled, all these arrangements, replacement, combination and
Partition is each fallen within the scope of the present invention.
It should be noted that in the description of this specification, the orientation or position relationship of the instruction such as term "front", "rear" are
Based on orientation shown in the drawings or position relationship, it is for only for ease of and describes the present invention and simplify to describe, rather than instruction or dark
Show that the device or unit of meaning must be with specific directions, with specific azimuth configuration and operation, it is thus impossible to be interpreted as right
Limitation of the invention.
Unless otherwise defined, all of technologies and scientific terms used here by the article with belong to technical field of the invention
The implication that technical staff is generally understood that is identical.The term for being used in the description of the invention herein is intended merely to description tool
The purpose of the embodiment of body, it is not intended that invented in limitation.
Specific embodiment of the invention is described further with reference to the accompanying drawings and detailed description.
Fig. 1 is Novel room of the invention every the structural representation under defect plugging device compressive state, during Fig. 2 is Fig. 1
, every the structural representation at another visual angle of defect plugging device, Fig. 3 is Novel room of the invention for Novel room under compressive state
Structural representation after defect plugging device recovers shape, Fig. 4 is that the atrial septal defect plugging device in Fig. 3 recovers the another of shape
The structural representation at visual angle.Understood with reference to Fig. 1-4, Novel room of the invention includes first support body 3, the every defect plugging device
Two stake bodies 4, the first fixedly connected part 1 and the second fixedly connected part 2, wherein first support body 3 and second support body 4 is by that can press
The braiding of Memorability metal alloy wires 6 of compression deformation is formed, wherein the two ends of the Memorability metal alloy wires 6 in first support body 3
It is respectively fixedly connected with the front end of the front end of the first fixedly connected part 1 and the second fixedly connected part 2, the note in second support body 4
The two ends of the property recalled metal alloy wires 6 are respectively fixedly connected with behind the rear end of the first fixedly connected part 1 and the second fixedly connected part 2
End, i.e. one end of Memorability metal alloy wires 6 in first support body 3 is fixedly connected on the front end of the first fixedly connected part 1, and
The other end is fixedly connected on the front end of the second fixedly connected part 2, one end of the Memorability metal alloy wires 6 in second support body 4
The rear end of the first fixedly connected part 1 is fixedly connected on, and the other end is fixedly connected on the rear end of the second fixedly connected part 2；First
Fixedly connected part 1 is with the second fixedly connected part 2 for the front end of cylindrical-shaped structure and the first fixedly connected part 1 is fixedly connected with second
The rear end of part 2 is provided with internal thread 5 and is used to connect induction system, and internal thread 5 is arranged at the first fixedly connected part 1 in the present embodiment
Front end and the second fixedly connected part 2 rear end；But plugging device of the present invention is also included not shown in thin-film barrier layers but figure, its
Middle thin-film barrier layers are built into first support body 3 and second support body 4.
Tubular dictyosome structure is shaped as after the first support body 3 and the compression of second support body 4, whole plugging device is existed
It is cylindric under compressive state.The structure can be easily got at atrial septal defect very much when in use.
The preset shape of the first support body 3 and second support body 4 is the lantern-shaped of intermediate projections.When using, due to
Memorability metal alloy persistently returns modeling, and first support body 3 and second support body 4 recover to lantern-shaped set in advance, due to lamp
The first support body 3 and second support body 4 of caged form larger clamping force and whole plugging device is preferably clamped room
Septal defect edge, closed room is every defect.
Memorability metal alloy wires 6 in the first support body 3 and second support body 4 are 25, but its Memorability
The quantity of metal alloy wires 6 can be also other numbers, preferably within the scope of 20-30.If first support body 3 and second support
Very little, then first support body 3 and second support body 4 cannot form enough folders to the number of the Memorability metal alloy wires in body 4
, every defect, easily there is obscission with closed room in the edge of clamp force clamping atrial septal defect；, whereas if first support body 3
Number with the Memorability metal alloy wires in second support body 4 is too many, then the weight of plugging device can then be dramatically increased, same meeting
The risk that increase comes off.Additionally, in order to obtain preferable clamping force to completely enclose atrial septal defect, the first support
It is solid that Memorability metal alloy wires 6 in body 3 and second support body 4 are equably fixedly connected on the first fixedly connected part 1 and second
Determine on connector 2.
The first support body 3 and second support body 4 recover the lantern-shaped of intermediate projections during the lantern-shaped to intermediate projections
Intermediate projections at longitudinal section be circle, and its a diameter of 5mm-50mm.Novel room of the invention is big every defect plugging device
It is small in the relatively wide in range scope, can be according to by estimating in advance under the cooperation of X-ray, angiography and color ultrasound
The size of atrial septal defect and select the first support body 3 and second support body 4 of suitable size, be better achieved plugging device with
The perfect cooperation of atrial septal defect.
Additionally, a diameter of 0.1- of the Memorability metal alloy wires 6 in the first support body 3 and second support body 4
0.2mm.If the diameter of the Memorability metal alloy wires 6 in first support body 3 and second support body 4 is too small, first support
Body 3 and second support body 4 are too thin and intensity is too small due to Memorability metal alloy wires 6, also without enough support forces, so that whole
The individual easy shape of plugging device；, whereas if the diameter of Memorability metal alloy wires 6 in first support body 3 and second support body 4 is too
Greatly, then the weight of plugging device can then be dramatically increased, and can increase the risk for coming off.
In addition, first fixedly connected part 1, the second fixedly connected part 2, first support body 3 and the surface of second support body 4
Carbon thin film layer is coated with, so as to improve the antiseptic effect of whole plugging device and prevent metal ion from entering blood, blood is effectively controlled
The formation of bolt, so that using safer.
Outside, the length of the fixedly connected part 2 of first fixedly connected part 1 and second is 1mm-3mm, preferably 1mm-2mm.
If the length of the first fixedly connected part 1 and the second fixedly connected part 2 is too small, its internal number of turns of internal thread 5 is very few, can draw
Rise and be connected with induction system insecure and there is the risk that plugging device comes off with induction system in art；, whereas if first is solid
The length for determining the fixedly connected part 2 of connector 1 and second is excessive, then can increase the risk that plugging device surface local thrombus are formed, and
And be easily caused first support body 3 and recover to the first fixedly connected part 1 during preset shape to be fixedly connected with second with second support body 4
The distance between part 2 is too small, the soft-sided of influence first support body 3 and the clamping atrial septal defect of second support body 4.
Also, the internal diameter of the fixedly connected part 2 of first fixedly connected part 1 and second is 1mm-2mm, if first fixes
The internal diameter of the fixedly connected part 2 of connector 1 and second is too small, then the connection between the plugging device and fix bar is not firm；Conversely,
If the internal diameter of the first fixedly connected part 1 and the second fixedly connected part 2 is excessive, plugging device can be caused to fold size mistake after gathering
Greatly.
On the thin-film barrier layers, its by biocompatibility preferably material high constitute, such as PLA, polyglycolic acid and
Condensing model.The thin-film barrier layers constitute the biology that can significantly improve plugging device by the preferable macromolecular material of biocompatibility
Compatibility.
In addition, the thin-film barrier layers are biomembrane in uniform thickness, its thickness is 0.1mm-0.2mm.If film hinders
The thickness of interlayer is too small, then thin-film barrier layers are easy to be ruptured because of the impulsive force of blood flow；, whereas if thin-film barrier layers
Thickness is too big, then the weight of thin-film barrier layers is increased, and causes the weight of plugging device also to increase, and is unfavorable for closed room every defect.
During operation, now Novel room of the invention is connected every defect plugging device with induction system, by induction system
Plugging device is delivered at atrial septal defect, because of the characteristic of Memorability metal alloy, first support body and second support body are replied
To default shape to clamp the edge of atrial septal defect, then closed room discharges plugging device every defect, terminates operation.
The announcement and teaching of book according to the above description, those skilled in the art in the invention can also be to above-mentioned embodiment party
Formula is changed and changed.Therefore, the invention is not limited in specific embodiment disclosed and described above, to the one of invention
A little modifications and changes should also be as falling into scope of the claims of the invention.Although additionally, being used in this specification
Some specific terms, but these terms are merely for convenience of description, do not constitute any limitation to the present invention.
Claims (9)
1. every defect plugging device, it includes that thin-film barrier layers, first support body, second support body, first are consolidated to a kind of Novel room
Determine connector and the second fixedly connected part, it is characterised in that first support body and second support body by compressible deformation memory
Property metal alloy wires braiding form, the two ends of the wherein Memorability metal alloy wires in first support body are respectively fixedly connected with the
The front end of one fixedly connected part and the front end of the second fixedly connected part, the two ends of the Memorability metal alloy wires in second support body
It is respectively fixedly connected with the rear end of the rear end of the first fixedly connected part and the second fixedly connected part；First fixedly connected part and second
Fixedly connected part is provided with internal thread for the rear end of cylindrical-shaped structure and the front end of the first fixedly connected part and the second fixedly connected part
It is used to connect induction system；Thin-film barrier layers are built into first support body and second support body.
2. Novel room according to claim 1 is every defect plugging device, it is characterised in that first fixedly connected part and
The length of the second fixedly connected part is 1mm-3mm, preferably 1mm-2mm, and its a diameter of 1mm-2mm.
3. Novel room according to claim 1 is every defect plugging device, it is characterised in that the thin-film barrier layers are thickness
Uniform biomembrane, its thickness is 0.1mm-0.2mm.
4. Novel room according to claim 1 is every defect plugging device, it is characterised in that the first support body and
The preset shape of second support body is the lantern-shaped of intermediate projections.
5. Novel room according to claim 4 is every defect plugging device, it is characterised in that the first support body and second
The longitudinal section that stake body recovers during the lantern-shaped to intermediate projections at the intermediate projections of the lantern-shaped of intermediate projections is circle, and its
A diameter of 5mm-50mm.
6. the Novel room according to any one of claim 1-5 is every defect plugging device, it is characterised in that described first
The quantity of the Memorability metal alloy wires in support body and second support body is 20-30.
7. the Novel room according to any one of claim 1-5 is every defect plugging device, it is characterised in that described first
A diameter of 0.1-0.2mm of the Memorability metal alloy wires in support body and second support body.
8. the Novel room according to any one of claim 1-5 is every defect plugging device, it is characterised in that described first consolidates
Determine connector, the second fixedly connected part, first support body and second support body surface face and be coated with carbon thin film layer.
9. the Novel room according to any one of claim 1-5 is every defect plugging device, it is characterised in that described first
Tubular dictyosome structure is shaped as after support body and the compression of second support body.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710159779.5A CN106821427B (en) | 2017-03-17 | 2017-03-17 | A kind of Novel room is every defect plugging device |
| PCT/CN2018/078145 WO2018166377A1 (en) | 2017-03-17 | 2018-03-06 | New occluding device for septal defect |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710159779.5A CN106821427B (en) | 2017-03-17 | 2017-03-17 | A kind of Novel room is every defect plugging device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106821427A true CN106821427A (en) | 2017-06-13 |
| CN106821427B CN106821427B (en) | 2019-09-20 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710159779.5A Expired - Fee Related CN106821427B (en) | 2017-03-17 | 2017-03-17 | A kind of Novel room is every defect plugging device |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN106821427B (en) |
| WO (1) | WO2018166377A1 (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018166377A1 (en) * | 2017-03-17 | 2018-09-20 | 广州新诚生物科技有限公司 | New occluding device for septal defect |
| CN109758194A (en) * | 2019-02-27 | 2019-05-17 | 武汉唯柯医疗科技有限公司 | Atrial septum plugging device and plugging device preparation method |
| CN114224402A (en) * | 2020-09-09 | 2022-03-25 | 江苏朴芃医疗科技有限公司 | Plugging device |
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|---|---|---|---|---|
| US20090076541A1 (en) * | 2007-09-13 | 2009-03-19 | Cardia, Inc. | Occlusion device with centering arm |
| CN101450013A (en) * | 2007-11-28 | 2009-06-10 | 王涛 | Blocking device of heart atrial, ventricular septal defect and patent oval foramen |
| CN207323503U (en) * | 2017-03-17 | 2018-05-08 | 广州新诚生物科技有限公司 | A kind of Novel room is every defect plugging device |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101449986B (en) * | 2007-11-28 | 2011-08-31 | 王涛 | Obturator of aorta ductus arteriosus |
| CN106821427B (en) * | 2017-03-17 | 2019-09-20 | 广州新诚生物科技有限公司 | A kind of Novel room is every defect plugging device |
-
2017
- 2017-03-17 CN CN201710159779.5A patent/CN106821427B/en not_active Expired - Fee Related
-
2018
- 2018-03-06 WO PCT/CN2018/078145 patent/WO2018166377A1/en active Application Filing
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090076541A1 (en) * | 2007-09-13 | 2009-03-19 | Cardia, Inc. | Occlusion device with centering arm |
| CN101450013A (en) * | 2007-11-28 | 2009-06-10 | 王涛 | Blocking device of heart atrial, ventricular septal defect and patent oval foramen |
| CN207323503U (en) * | 2017-03-17 | 2018-05-08 | 广州新诚生物科技有限公司 | A kind of Novel room is every defect plugging device |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018166377A1 (en) * | 2017-03-17 | 2018-09-20 | 广州新诚生物科技有限公司 | New occluding device for septal defect |
| CN109758194A (en) * | 2019-02-27 | 2019-05-17 | 武汉唯柯医疗科技有限公司 | Atrial septum plugging device and plugging device preparation method |
| CN109758194B (en) * | 2019-02-27 | 2020-06-26 | 武汉唯柯医疗科技有限公司 | Atrial septum plugging device |
| CN114224402A (en) * | 2020-09-09 | 2022-03-25 | 江苏朴芃医疗科技有限公司 | Plugging device |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106821427B (en) | 2019-09-20 |
| WO2018166377A1 (en) | 2018-09-20 |
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