CN106772529A - A kind of dose of radiation remains activity value monitoring method and system - Google Patents

A kind of dose of radiation remains activity value monitoring method and system Download PDF

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Publication number
CN106772529A
CN106772529A CN201611069864.4A CN201611069864A CN106772529A CN 106772529 A CN106772529 A CN 106772529A CN 201611069864 A CN201611069864 A CN 201611069864A CN 106772529 A CN106772529 A CN 106772529A
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Prior art keywords
destination object
dose
residual
residual dose
ratio
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CN106772529B (en
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李高峰
李亚明
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Beijing Standard Time Science And Technology Development Co Ltd
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Beijing Standard Time Science And Technology Development Co Ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01TMEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/16Measuring radiation intensity
    • G01T1/167Measuring radioactive content of objects, e.g. contamination
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01TMEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/02Dosimeters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01TMEASUREMENT OF NUCLEAR OR X-RADIATION
    • G01T1/00Measuring X-radiation, gamma radiation, corpuscular radiation, or cosmic radiation
    • G01T1/16Measuring radiation intensity
    • G01T1/17Circuit arrangements not adapted to a particular type of detector
    • G01T1/178Circuit arrangements not adapted to a particular type of detector for measuring specific activity in the presence of other radioactive substances, e.g. natural, in the air or in liquids such as rain water

Abstract

The invention discloses a kind of dose of radiation residual activity value monitoring method, method includes that the destination object to taking radiation agent carries out radiation agent Residual dose scanning, obtains the measurement Residual dose at each position in multiple positions of destination object.The ratio of the total amount of the radiation agent that the measurement Residual dose and destination object for calculating each position of destination object are taken, obtains the residual activity of the measurement Residual dose at each position of destination object.Obtain the Residual dose distribution map of destination object.Each position of correction destination object measurement Residual dose, makes each position of destination object measurement Residual dose proportionate relationship and each position of destination object distribution Residual dose ratio consistent, obtains each position of destination object correction Residual dose.The ratio that destination object multiple position correction Residual dose total amount takes radiation agent total amount with destination object is calculated, destination object whole body correction Residual dose residual activity is obtained.

Description

A kind of dose of radiation remains activity value monitoring method and system
Technical field
The present invention relates to NMT field, activity value monitoring method is remained more particularly, to a kind of dose of radiation And system.
Background technology
At present, high energy element is more and more extensive in the application of nuclear medicine, for example131I elements, especially will131I is applied to first Shape gland disease, such as131After the diagnostic total body opacifications of I, treatment131I total body opacifications,131I removes thyroid cancer Postoperative Residual thyroid gland Tissue and treatment recurrence and transfer tissue etc., evident in efficacy, safe ready, therefore be China's radionuclide therapy with fastest developing speed Mesh.According to China's occupational health standard, receive131Residual activity activity is reduced to 400MBq rears in patient's body after I treatments Can leave hospital.
At present in the field of nuclear medicine, measurement receives131Residual activity activity in patient's body after I treatments, existing and sheet The most close implementation of patent is as follows:
Acquisition method:Clothes131Patient's empty bladder is advised before I, respectively at clothes1312h, 6h, 24h, 48h, 72h are carried out after I SPECT generalized phenomenas, record total body opacification is counted.
Evaluation method:Clothes131Patient fasts are advised after I in 2h, draining urine and excrement are avoided as far as possible, it is aobvious with the whole body of 2h As tale correspondence is taken131I accumulated doses, thereafter according to variant time point and the imaging count ratio of 2h, calculate different time The percentage remained in vivo in point, residual activity activity in estimation patient's body.
Prior art is for clothes131The testing result deviation that activity is remained after I is larger, it is impossible to taken exactly131After I Residual activity in destination object.
The content of the invention
The present invention provides a kind of dose of radiation residual activity value monitoring method and system, to solve to take131Target pair after I As interior residual activity monitoring precision problem not high.
To solve the above problems, the present invention provides a kind of method methods described to be included,
Destination object to taking radiation agent carries out radiation agent Residual dose scanning, in multiple positions of acquisition destination object The measurement Residual dose at each position;
The total amount of the radiation agent that the measurement Residual dose and destination object for calculating each position of destination object are taken Ratio, obtain the residual activity of the measurement Residual dose at destination object each position;
The Residual dose distribution map of destination object is obtained, the residual agent distribution map of the destination object includes that destination object is more Each position distribution Residual dose accounts for the criteria weights of destination object distribution residual accumulated dose in individual position, and destination object is each Position is distributed Residual dose ratio;
Each position of destination object measurement Residual dose is corrected, each position of destination object is measured Residual dose ratio Example relation and each position of destination object distribution Residual dose ratio are consistent, obtain each position of destination object correction residual agent Amount;And
Calculate the destination object multiple position correction Residual dose total amount and destination object takes the ratio of radiation agent total amount Value, obtains destination object whole body correction Residual dose residual activity.
Preferably, the acquisition destination object whole body Residual dose distribution map includes:
The destination object of radiation agent is taken to multiple carries out radiation agent Residual dose scanning, obtain multiple destination objects each Position measures Residual dose;Each site residues dosage of each destination object accounts for destination object whole body in the multiple destination objects of calculating The ratio of Residual dose, and destination object whole body residual is accounted for each site residues dosage of each destination object in multiple destination objects The ratio of dosage is averaged, and building each each position distribution Residual dose of destination object using average value accounts for destination object whole body Distribution Residual dose weight, and each position of destination object distribution Residual dose ratio.
Preferably, each position of destination object measurement Residual dose is corrected, measures each position of destination object residual Stay dose ratio relation and each position of destination object distribution Residual dose ratio consistent, obtain each position correction of destination object residual Staying dosage includes:
Judge that each position of the measurement Residual dose proportionate relationship and destination object distribution of each position of the destination object is residual Stay dose ratio whether consistent;
If consistent, need not be corrected;
If inconsistent, it is corrected according to the following steps:
Step 1, chooses measurement Residual dose and sorts position high for calibration standard Residual dose, other each site residues agent Amount is that reference is corrected with calibration standard Residual dose, the correction of each position of the destination object Residual dose and the target Each position of object distribution Residual dose ratio is consistent;
Step 2, the position for choosing measurement Residual dose sequence second is calibration standard Residual dose, other each site residues Dosage is that reference is corrected with calibration standard Residual dose, the correction of each position of the destination object Residual dose and the mesh Distribution Residual dose ratio in each position of mark object is consistent;
Step 3, each position correction Residual dose obtained after the step 1 and step 2 are corrected is averaged, and is obtained most Each position corrects Residual dose eventually.
Based on another embodiment of the invention, the present invention provides a kind of system, and the system includes,
Scanning element, for carrying out radiation agent Residual dose scanning to the destination object for taking radiation agent, obtains target pair As each position measures Residual dose;
Computing unit, for calculating each position of destination object measurement Residual dose, to take radiation agent with destination object total The ratio of amount, obtains each position measurement Residual dose residual activity of destination object;
Reference data unit, for obtaining destination object whole body Residual dose distribution map, the destination object whole body residual Agent distribution map includes that each position distribution Residual dose of destination object accounts for destination object whole body distribution Residual dose weight, and target Each position distribution Residual dose ratio of object;
Correction unit, for correcting each position measurement Residual dose of the destination object, measures each position of destination object Residual dose proportionate relationship and each position distribution Residual dose ratio of destination object are consistent, obtain each position correction of destination object residual Stay dosage;And
Analytic unit, radiation is taken for calculating each position correction Residual dose total amount of the destination object with destination object The ratio of agent total amount, obtains destination object whole body correction Residual dose residual activity.
Preferably, the reference data unit is additionally operable to:The destination object of radiation agent is taken to multiple, and to carry out radiation agent residual Dose scan is stayed, each position measurement Residual dose of multiple destination objects is obtained;Calculate each destination object in multiple destination objects Each site residues dosage accounts for the ratio of destination object whole body Residual dose, and to each portion of each destination object in multiple destination objects The ratio that position Residual dose accounts for destination object whole body Residual dose is averaged, and each position of destination object point is built using average value Cloth Residual dose accounts for destination object whole body distribution Residual dose weight, and each position distribution Residual dose ratio of destination object.
Preferably, the correction unit is additionally operable to:
Judge each position measurement Residual dose proportionate relationship of the destination object with each position distribution residual agent of destination object Whether amount ratio is consistent;
If consistent, need not be corrected;
If inconsistent, it is corrected according to the following steps:
Step 1, chooses measurement Residual dose and sorts position high for calibration standard Residual dose, other each site residues agent Amount is that reference is corrected with calibration standard Residual dose, the correction of each position of the destination object Residual dose and the target Each position of object distribution Residual dose ratio is consistent;
Step 2, the position for choosing measurement Residual dose sequence second is calibration standard Residual dose, other each site residues Dosage is that reference is corrected with calibration standard Residual dose, the correction of each position of the destination object Residual dose and the mesh Distribution Residual dose ratio in each position of mark object is consistent;
Step 3, each position correction Residual dose obtained after the step 1 and step 2 are corrected is averaged, and is obtained most Each position corrects Residual dose eventually.
Based on another embodiment of the invention, the present invention provides a kind of system, and the system includes:Base, supporter, Control device, height detection device, lowering or hoisting gear, detection device, computing device, reference data device, means for correcting and analysis Device;Wherein,
The base is connected with the supporter, for carrying the patient in standing state;
The height detection device is installed on the supporter, the height for detecting the patient;
The control device is electrically connected with the height detection device, for receiving the height, and according to the height Determine initial sweep position and terminal scan position, and send drive signal and scanning signal;
The lowering or hoisting gear can up or down be installed on the supporter, and the detection device is installed on the lifting dress Put;The lowering or hoisting gear is electrically connected with the control device, for receiving the drive signal, and according to the drive signal band Move the detection device and the terminal scan position is moved to by the initial sweep position;
The detection device is electrically connected with the control device, for receiving the scanning signal, and according to the scanning Signal is scanned to the patient, and the control device is additionally operable to receive scanning result and determine institute according to the scanning result State each position dose of radiation Residual dose in patient's body;
Computing device, for calculating each position of destination object measurement Residual dose, to take radiation agent with destination object total The ratio of amount, obtains each position measurement Residual dose residual activity of destination object;
Reference data device, for obtaining destination object whole body Residual dose distribution map, the destination object whole body residual Agent distribution map includes that each position distribution Residual dose of destination object accounts for destination object whole body distribution Residual dose weight, and target Each position distribution Residual dose ratio of object;
Means for correcting, for correcting each position measurement Residual dose of the destination object, measures each position of destination object Residual dose proportionate relationship and each position distribution Residual dose ratio of destination object are consistent, obtain each position correction of destination object residual Stay dosage;And
Analytical equipment, radiation is taken for calculating each position correction Residual dose total amount of the destination object with destination object The ratio of agent total amount, obtains destination object whole body correction Residual dose residual activity.
Preferably, it is characterised in that the detection device includes:Collimater and linear array detector;Wherein,
The collimater is provided with multiple passages, is used to receive the ray of transmitting in patient's body;
The linear array detector includes multiple probe units, also, a pair of each probe unit and each passage 1 Should set, each probe unit is used to receive and process the ray of the passage transmission, and output digit signals;
The control device is electrically connected with the probe unit, for receiving the data signal, and according to the numeral Signal determines patient's Radioimmunoimaging residual distribution.
Preferably, it is characterised in that the height detection device is for multiple and is arranged side by side.
Preferably, it is characterised in that the height detection device is ultrasonic detection device.
Preferably, it is characterised in that also include:Display;Wherein,
The display is electrically connected with the control device, and the dose of radiation for showing the patient remains distribution.
Preferably, it is characterised in that the supporter includes:Support body and top board;Wherein,
It is described support body first end be connected with the base, it is described support body the second end and the top board phase Connection, the top board is oppositely arranged with the base;
The height detection device is installed on the top board;The lowering or hoisting gear is installed on the support body.
Preferably, it is characterised in that the lowering or hoisting gear includes:Drive mechanism, guide rail, connecting plate, sliding block and chain;Its In,
The guide rail is set along the short transverse of the support body, and the sliding block is connected with the slide;
The input of the drive mechanism is electrically connected with the control device, and output end is connected with the chain, described Drive mechanism is used to receive the drive signal, and drives the chain to move up and down according to the drive signal;
The chain is connected by the connecting plate with the sliding block, for driving the connecting plate to be swept by the starting Retouch position and be moved to the terminal scan position;
The detection device is installed on the connecting plate.
Preferably, it is characterised in that the drive mechanism is motor.
Preferably, it is characterised in that also include:Two handles;Wherein,
Two handles are mounted on the supporter and are placed in the both sides of the supporter.
Technical scheme, patient stand is in base, also, detection device is following lowering or hoisting gear by initial sweep Position is scanned during moving scan position to terminal to patient, and so, operator is without carry out pendulum position to patient i.e. Patient can be scanned, efficiently avoid operator and receive more radiation, it is simple to operate, also, detection device passes through Lowering or hoisting gear is installed on supporter, then detection device is placed in the body side in the patient of standing state, efficiently avoid spy Device extruding patient is surveyed, complex operation when prior art is monitored to dose of radiation residual, operator is solved and is received radiation Problem that is more and easily extruding patient.Additionally, control device determines initial sweep position according to the height of the patient for detecting With terminal scan position, without carrying out whole scannings from top to bottom to patient, sweep time is substantially reduced, improve scanning Efficiency, while the amount of radiation that the monitoring device for reducing patient's receiving is distributed.
Technical solution of the present invention obtains final goal object total residual activity, and monitoring method deviation of the invention is small, accurately Degree is high.
Brief description of the drawings
By reference to the following drawings, illustrative embodiments of the invention can be more fully understood by:
Fig. 1 is a kind of dose of radiation residual activity value monitoring method flow chart of one embodiment of the present invention;
Fig. 2 is a kind of dose of radiation residual activity value observation system structure chart of one embodiment of the present invention;
Fig. 3 is a kind of dose of radiation residual activity value observation system structure chart of one embodiment of the present invention.
Specific embodiment
With reference now to accompanying drawing, illustrative embodiments of the invention are introduced, however, the present invention can use many different shapes Formula is implemented, and is not limited to embodiment described herein, there is provided these embodiments are to disclose at large and fully The present invention, and fully pass on the scope of the present invention to person of ordinary skill in the field.For showing for being illustrated in the accompanying drawings Term in example property implementation method is not limitation of the invention.In the accompanying drawings, identical cells/elements are attached using identical Icon is remembered.
Unless otherwise indicated, term (including scientific and technical terminology) used herein has to person of ordinary skill in the field It is common to understand implication.Further it will be understood that the term limited with usually used dictionary, is appreciated that and it The linguistic context of association area has consistent implication, and is not construed as Utopian or excessively formal meaning.
Fig. 1 is a kind of dose of radiation residual activity value monitoring method flow chart of one embodiment of the present invention.Method 100 is solved Determine and how to have accurately measured patient's Radioimmunoimaging residual activity value, due to the Residual dose that can be measured with partes corporis humani position It is corrected, method error of measuring value proposed by the present invention is small.
Preferably, method 100 starts to walk from 101:Destination object to taking radiation agent carries out radiation agent Residual dose scanning. Destination object to taking radiation agent carries out radiation agent Residual dose scanning, obtains each position in multiple positions of destination object Measurement Residual dose.In embodiments of the present invention, patient is residual to personal radiation agent using dose of radiation Residue Monitoring device Dosage is stayed to be scanned.(referring to Fig. 3, Fig. 1 is not shown).In embodiments of the present invention, total radiation dosage 100 is taken with human body As a example by unit, each site residues dosage is the unit of thyroid gland position 17, the unit of lung 9, wing after scanning human body takes dose of radiation The unit of Guang 25, other positions add up to 12 units.
Step 102:The radiation agent that the measurement Residual dose and destination object for calculating each position of destination object are taken The ratio of total amount.The total amount of the radiation agent that the measurement Residual dose and destination object for calculating each position of destination object are taken Ratio, obtains the residual activity of the measurement Residual dose at each position of destination object.It is residual with each position radiation agent that step 1 is measured Stay as a example by dosage, each position radiation agent for calculating human body remains activity for thyroid gland position 17%, lung 9%, bladder 25%, its He adds up to 12% in position.
Step 103:Obtain the Residual dose distribution map of destination object.Obtain the Residual dose distribution map of destination object, mesh The residual agent distribution map for marking object accounts for destination object distribution including each position distribution Residual dose in destination object multiple positions Remain the criteria weights of accumulated dose, and each position distribution Residual dose ratio of destination object.The mesh of radiation agent is taken to multiple Mark object carries out radiation agent Residual dose scanning, obtains multiple each position of destination object measurement Residual doses.The present invention is implemented Still so that human body takes the unit of total radiation dosage 100 as an example, scanning human body takes each site residues dosage number after dose of radiation to example Value is shown in Table one.Each site residues dosage of each destination object accounts for destination object whole body Residual dose in the multiple destination objects of calculating Ratio, and the ratio of destination object whole body Residual dose is accounted for each site residues dosage of each destination object in multiple destination objects Example is averaged, and numerical computations are illustrated see table two.Each each position distribution residual of destination object is built using average value Dosage accounts for destination object whole body distribution Residual dose weight, and each position of destination object distribution Residual dose ratio.
Table one
Table two
As shown in Table 2, each site residues dosage accounts for destination object whole body distribution Residual dose weight point after taking radiation agent Cloth is thyroid gland position 31%, lung 24%, bladder 31%, other positions total 14%.Or by each site residues of whole body Dose lonvestion is proportionate relationship, and each site residues dose weights proportionate relationship is close to:Thyroid gland position:Lung:Bladder:Other Position total=2:1.5:2:1.
Step 104, each position of correction destination object measurement Residual dose.Each position of correction destination object measurement residual Dosage, makes each position of destination object measure Residual dose proportionate relationship and each position of destination object distribution Residual dose ratio Unanimously, each position of destination object correction Residual dose is obtained.Judge that each position of destination object measurement Residual dose ratio is closed Whether system is consistent with each position of destination object distribution Residual dose ratio;
If consistent, need not be corrected;
If inconsistent, it is corrected according to the following steps:
Step 1, chooses measurement Residual dose and sorts position high for calibration standard Residual dose, other each site residues agent Amount with calibration standard Residual dose be with reference to being corrected, each position of destination object correction Residual dose and destination object each Position distribution Residual dose ratio is consistent;
Step 2, the position for choosing measurement Residual dose sequence second is calibration standard Residual dose, other each site residues Dosage is that reference is corrected with calibration standard Residual dose, and each position of destination object correction Residual dose is every with destination object Individual position distribution Residual dose ratio is consistent;
Step 3, each position correction Residual dose obtained after step 1 and step 2 are corrected is averaged, and obtains final every Individual position corrects Residual dose.
So that step 101 human body takes the unit of total radiation dosage 100 as an example, each position is residual after scanning human body takes dose of radiation Stay dosage for the unit of thyroid gland position 17, the unit of lung 9, the unit of bladder 25, other positions add up to 12 units, with reference to step 103 In take each site residues dosage after radiation agent and account for destination object whole body distribution Residual dose weight distribution or proportionate relationship, first shape Gland position:Lung:Bladder:Other positions total=2:1.5:2:1, it is calibration standard location first with bladder with partial, to human body Each site residues dosage is calibrated, and the partes corporis humani position Residual dose after calibration is:The unit of thyroid gland position 25, lung 17 is single Position, the unit of bladder 25, other positions add up to 13 units;It is again calibration standard location with thyroid gland position, it is residual to partes corporis humani position Dosage is stayed to be calibrated, the partes corporis humani position Residual dose after calibration is:The unit of thyroid gland position 14, the unit of lung 13, bladder 17 units, other positions add up to 9 units;Data after calibrating twice are averaged, final each position correction residual is obtained Dosage is the unit of thyroid gland position 21, and the unit of lung 15, the unit of bladder 21, other positions add up to 11 units.
Table three
Step 105, calculates destination object multiple position correction Residual dose total amount and takes radiation agent total amount with destination object Ratio, obtain destination object whole body correction Residual dose residual activity.Destination object multiple position correction Residual dose summation It is 68, wherein:The unit of thyroid gland position 21, the unit of lung 15, the unit of bladder 21, other positions add up to 11 units.Obtain target Object whole body correction Residual dose residual activity is 68%.
Final goal object total residual activity is obtained using technical solution of the present invention, monitoring method deviation of the invention is small, The degree of accuracy is high.
Fig. 2 is a kind of dose of radiation residual activity value observation system structure chart of one embodiment of the present invention.System includes, Scanning element 201, for carrying out radiation agent Residual dose scanning to the destination object for taking radiation agent, obtains each portion of destination object Position measurement Residual dose.Computing unit 202, spoke is taken for calculating each position measurement Residual dose of destination object with destination object The ratio of agent total amount is penetrated, each position measurement Residual dose residual activity of destination object is obtained.Reference data unit 203, for obtaining Destination object whole body Residual dose distribution map is taken, destination object whole body residual agent distribution map includes that each position distribution of destination object is residual Dosage is stayed to account for destination object whole body distribution Residual dose weight, and each position distribution Residual dose ratio of destination object.Correction Unit 204, for correcting each position measurement Residual dose of destination object, closes each position measurement Residual dose ratio of destination object System is consistent with each position distribution Residual dose ratio of destination object, obtains each position correction Residual dose of destination object.Analysis is single Unit 205, the ratio of radiation agent total amount is taken for calculating each position correction Residual dose total amount of destination object with destination object, is obtained Take destination object whole body correction Residual dose residual activity.
Preferably, reference data unit 203 is additionally operable to:The destination object that radiation agent is taken to multiple carries out radiation agent residual Dose scan, obtains each position measurement Residual dose of multiple destination objects;Each destination object is each in calculating multiple destination objects Site residues dosage accounts for the ratio of destination object whole body Residual dose, and to each position of each destination object in multiple destination objects The ratio that Residual dose accounts for destination object whole body Residual dose is averaged, and building each position of destination object using average value is distributed Residual dose accounts for destination object whole body distribution Residual dose weight, and each position distribution Residual dose ratio of destination object.
Preferably, correction unit 204 is additionally operable to:
Judge each position measurement Residual dose proportionate relationship of destination object with each position distribution Residual dose ratio of destination object Whether example is consistent;
If consistent, need not be corrected;
If inconsistent, it is corrected according to the following steps:
Step 1, chooses measurement Residual dose and sorts highest position from big to small for calibration standard Residual dose, and other are each Site residues dosage is that reference is corrected with calibration standard Residual dose, the correction of each position of destination object Residual dose and mesh Distribution Residual dose ratio in each position of mark object is consistent;
Step 2, the position for choosing measurement Residual dose sequence second is calibration standard Residual dose, other each site residues Dosage is that reference is corrected with calibration standard Residual dose, and each position of destination object correction Residual dose is every with destination object Individual position distribution Residual dose ratio is consistent;
Step 3, each position correction Residual dose obtained after step 1 and step 2 are corrected is averaged, and obtains final every Individual position corrects Residual dose.
The function of system 200 is corresponding with method 100, is no longer repeated herein.
Fig. 3 is a kind of dose of radiation residual activity value observation system structure chart of one embodiment of the present invention.Such as Fig. 3 institutes Show, system 300 includes:301st, supporter, control device 304, height detection device 305, lowering or hoisting gear 307, detection device 306th, computing device 308, reference data device 309, means for correcting 310 and analytical equipment 311;Wherein,
Base 301 is connected with supporter, for carrying the patient in standing state;
Height detection device 305 is installed on supporter, the height for detecting patient;
Control device 304 is electrically connected with height detection device 305, for receiving height, and determines that starting is swept according to height Position and terminal scan position are retouched, and sends drive signal and scanning signal;
Lowering or hoisting gear 307 can up or down be installed on supporter, and detection device 306 is installed on lowering or hoisting gear;Lifting dress Put 307 to be electrically connected with control device 304, for receiving drive signal, and drive detection device to be swept by starting according to drive signal Retouch position movement scan position to terminal;
Detection device 306 is electrically connected with control device 304, for receiving scanning signal, and according to scanning signal to patient It is scanned, control device 304 is additionally operable to receive scanning result and determine each position radiation agent in patient's body according to scanning result Amount Residual dose;
Computing device 308, for calculating each position of destination object measurement Residual dose, to take radiation agent with destination object total The ratio of amount, obtains each position measurement Residual dose residual activity of destination object;
Reference data device 309, for obtaining destination object whole body Residual dose distribution map, the residual agent of destination object whole body Distribution map includes that each position distribution Residual dose of destination object accounts for destination object whole body distribution Residual dose weight, and target pair As each position is distributed Residual dose ratio.Reference data device 309, the destination object for being additionally operable to take multiple radiation agent is carried out Radiation agent Residual dose is scanned, and obtains each position measurement Residual dose of multiple destination objects;Calculate each in multiple destination objects Each site residues dosage of destination object accounts for the ratio of destination object whole body Residual dose, and to each target in multiple destination objects The ratio that each site residues dosage of object accounts for destination object whole body Residual dose is averaged, and destination object is built using average value Each position distribution Residual dose accounts for destination object whole body distribution Residual dose weight, and each position distribution residual agent of destination object Amount ratio.
Means for correcting 310, for correcting each position measurement Residual dose of destination object, makes each position measurement of destination object residual Stay dose ratio relation and each position distribution Residual dose ratio of destination object consistent, obtain each position correction residual of destination object Dosage.Correction unit 310 is additionally operable to:
Judge each position measurement Residual dose proportionate relationship of destination object with each position distribution Residual dose ratio of destination object Whether example is consistent;
If consistent, need not be corrected;
If inconsistent, it is corrected according to the following steps:
Step 1, chooses measurement Residual dose and sorts highest position from big to small for calibration standard Residual dose, and other are each Site residues dosage is that reference is corrected with calibration standard Residual dose, the correction of each position of destination object Residual dose and mesh Distribution Residual dose ratio in each position of mark object is consistent;
Step 2, the position for choosing measurement Residual dose sequence second is calibration standard Residual dose, other each site residues Dosage is that reference is corrected with calibration standard Residual dose, and each position of destination object correction Residual dose is every with destination object Individual position distribution Residual dose ratio is consistent;
Step 3, each position correction Residual dose obtained after step 1 and step 2 are corrected is averaged, and obtains final every Individual position corrects Residual dose.
Analytical equipment 311, radiation is taken for calculating each position correction Residual dose total amount of destination object with destination object The ratio of agent total amount, obtains destination object whole body correction Residual dose residual activity.
Preferably, detection device includes:Collimater and linear array detector;Wherein,
Collimater is provided with multiple passages, is used to receive the ray of transmitting in patient's body;
Linear array detector includes multiple probe units, also, each probe unit is corresponded with each passage and set, each detection Unit is used to the ray for receiving and treatment channel is transmitted, and output digit signals;
Control device is electrically connected with probe unit, for receiving data signal, and is determined in patient's body according to data signal Dose of radiation residual distribution.
Preferably, it is characterised in that height detection device is for multiple and is arranged side by side.
Preferably, it is characterised in that height detection device is ultrasonic detection device.
Preferably, it is characterised in that also include:Display;Wherein,
Display is electrically connected with control device, and the dose of radiation for showing patient remains distribution.
Preferably, it is characterised in that supporter includes:Support body and top board;Wherein,
The first end of body is supported to be connected with base, the second end of support body is connected with top board, top board and base It is oppositely arranged;
Height detection device is installed on top board;Lowering or hoisting gear is installed on support body.
Preferably, it is characterised in that lowering or hoisting gear includes:Drive mechanism, guide rail, connecting plate, sliding block and chain;Wherein,
Guide rail is set along the short transverse of support body, and sliding block is connected with slide;
The input of drive mechanism is electrically connected with control device, and output end is connected with chain, and drive mechanism is used to receive Drive signal, and moved up and down according to drive signal drive chain;
Chain is connected by connecting plate with sliding block, for driving connecting plate to be scanned to terminal by the movement of initial sweep position Position;
Detection device is installed on connecting plate.
Preferably, it is characterised in that drive mechanism is motor.
Preferably, it is characterised in that also include:Two handles;Wherein,
Two handles are mounted on supporter and are placed in the both sides of supporter.
Patient stand remains stationary as state in base 301.Height detection device 305 detects the height of patient, and will inspection The height for measuring is sent to control device 304, and control device 304 receives the height, and determines initial sweep position according to the height Put with terminal scan position, and send drive signal and scanning signal.What 307 receiving control device of lowering or hoisting gear 304 sent Drive signal, and scan position to terminal is moved from initial sweep position according to drive signal.Because detection device 306 is installed on Lowering or hoisting gear 307, so the mobile drive detection device 306 of lowering or hoisting gear 307 is scanned to terminal by the movement of initial sweep position Position.306 receiving control device of detection device 304 send scanning signal, detection device 306 follow lowering or hoisting gear 307 by Initial sweep position is scanned during moving scan position to terminal to patient, and in real time by initial sweep position to end The body of the corresponding patient in all position places between spot scan position is scanned, and scanning result is sent in real time Control device 304.Control device 304 receives scanning result, and determines patient's Radioimmunoimaging residual point according to scanning result Cloth.After scanned, patient can leave base 301.
The present invention is described by reference to a small amount of implementation method.However, it is known in those skilled in the art, as What subsidiary Patent right requirement was limited, except the present invention other embodiments disclosed above equally fall of the invention In the range of.
Normally, all terms for using in the claims are all solved according to them in the usual implication of technical field Release, unless clearly defined in addition wherein.It is all of to be all opened ground with reference to " one/described/be somebody's turn to do [device, component etc.] " At least one of described device, component etc. example is construed to, unless otherwise expressly specified.Any method disclosed herein Step need not all be run with disclosed accurate order, unless explicitly stated otherwise.

Claims (15)

1. a kind of dose of radiation remains activity value monitoring method, and methods described includes,
Destination object to taking radiation agent carries out radiation agent Residual dose scanning, obtains each in multiple positions of destination object The measurement Residual dose at position;
The ratio of the total amount of the radiation agent that the measurement Residual dose and destination object for calculating each position of destination object are taken Value, obtains the residual activity of the measurement Residual dose at each position of destination object;
The Residual dose distribution map of destination object is obtained, the residual agent distribution map of the destination object includes destination object multiple portion Each position distribution Residual dose accounts for the criteria weights of destination object distribution residual accumulated dose, and each position of destination object in position Distribution Residual dose ratio;
Each position of destination object measurement Residual dose is corrected, each position of destination object is measured Residual dose ratio and is closed System is consistent with each position of destination object distribution Residual dose ratio, obtains each position of destination object correction Residual dose;With And
The ratio that the destination object multiple position correction Residual dose total amount takes radiation agent total amount with destination object is calculated, is obtained Take destination object whole body correction Residual dose residual activity.
2. method according to claim 1, the acquisition destination object whole body Residual dose distribution map includes:
The destination object of radiation agent is taken to multiple carries out radiation agent Residual dose scanning, obtains multiple each position of destination object Measurement Residual dose;Each site residues dosage of each destination object accounts for destination object whole body residual in the multiple destination objects of calculating The ratio of dosage, and destination object whole body Residual dose is accounted for each site residues dosage of each destination object in multiple destination objects Ratio average, build each each position distribution Residual dose of destination object using average value and account for destination object whole body and be distributed Residual dose weight, and each position of destination object distribution Residual dose ratio.
3. method according to claim 1, corrects each position of destination object measurement Residual dose, makes destination object Each position measures Residual dose proportionate relationship and each position of destination object distribution Residual dose ratio is consistent, obtains target pair As each position correction Residual dose includes:
Judge each position of destination object measurement Residual dose proportionate relationship with each position of destination object distribution residual agent Whether amount ratio is consistent;
If consistent, need not be corrected;
If inconsistent, it is corrected according to the following steps:
Step 1, chooses measurement Residual dose and sorts highest position from big to small for calibration standard Residual dose, other each positions Residual dose is that reference is corrected with calibration standard Residual dose, each position of the destination object correction Residual dose and institute State each position of destination object distribution Residual dose ratio consistent;
Step 2, the position for choosing measurement Residual dose sequence second is calibration standard Residual dose, other each site residues dosage It is that reference is corrected with calibration standard Residual dose, the correction of each position of the destination object Residual dose and the target pair As each position distribution Residual dose ratio is consistent;
Step 3, each position correction Residual dose obtained after the step 1 and step 2 are corrected is averaged, and obtains final every Individual position corrects Residual dose.
4. a kind of dose of radiation remains activity value observation system, and the system includes,
Scanning element, for carrying out radiation agent Residual dose scanning to the destination object for taking radiation agent, obtains destination object each Position measures Residual dose;
Computing unit, radiation agent total amount is taken for calculating each position measurement Residual dose of the destination object with destination object Ratio, obtains each position measurement Residual dose residual activity of destination object;
Reference data unit, for obtaining destination object whole body Residual dose distribution map, the destination object whole body residual agent point Butut includes that each position distribution Residual dose of destination object accounts for destination object whole body distribution Residual dose weight, and destination object Each position is distributed Residual dose ratio;
Correction unit, for correcting each position measurement Residual dose of the destination object, makes each position measurement residual of destination object Dose ratio relation and each position distribution Residual dose ratio of destination object are consistent, obtain each position correction residual agent of destination object Amount;And
Analytic unit, for calculating each position of destination object correction Residual dose total amount, to take radiation agent with destination object total The ratio of amount, obtains destination object whole body correction Residual dose residual activity.
5. system according to claim 4, the reference data unit is additionally operable to:The target pair of radiation agent is taken to multiple As carrying out radiation agent Residual dose scanning, each position measurement Residual dose of multiple destination objects is obtained;Calculate multiple destination objects In each site residues dosage of each destination object account for the ratio of destination object whole body Residual dose, and to every in multiple destination objects The ratio that individual each site residues dosage of destination object accounts for destination object whole body Residual dose is averaged, and mesh is built using average value Each position distribution Residual dose of mark object accounts for destination object whole body distribution Residual dose weight, and each position distribution of destination object Residual dose ratio.
6. system according to claim 4, the correction unit is additionally operable to:
Judge each position measurement Residual dose proportionate relationship of the destination object with each position distribution Residual dose ratio of destination object Whether example is consistent;
If consistent, need not be corrected;
If inconsistent, it is corrected according to the following steps:
Step 1, chooses measurement Residual dose and sorts highest position from big to small for calibration standard Residual dose, other each positions Residual dose is that reference is corrected with calibration standard Residual dose, each position of the destination object correction Residual dose and institute State each position of destination object distribution Residual dose ratio consistent;
Step 2, the position for choosing measurement Residual dose sequence second is calibration standard Residual dose, other each site residues dosage It is that reference is corrected with calibration standard Residual dose, the correction of each position of the destination object Residual dose and the target pair As each position distribution Residual dose ratio is consistent;
Step 3, each position correction Residual dose obtained after the step 1 and step 2 are corrected is averaged, and obtains final every Individual position corrects Residual dose.
7. a kind of dose of radiation Residual dose monitoring system, it is characterised in that including:Base, supporter, control device, height Detection means, lowering or hoisting gear, detection device, computing device, reference data device, means for correcting and analytical equipment;Wherein,
The base is connected with the supporter, for carrying the patient in standing state;
The height detection device is installed on the supporter, the height for detecting the patient;
The control device is electrically connected with the height detection device, for receiving the height, and is determined according to the height Initial sweep position and terminal scan position, and send drive signal and scanning signal;
The lowering or hoisting gear can up or down be installed on the supporter, and the detection device is installed on the lowering or hoisting gear; The lowering or hoisting gear is electrically connected with the control device, for receiving the drive signal, and is driven according to the drive signal The detection device is moved to the terminal scan position by the initial sweep position;
The detection device is electrically connected with the control device, for receiving the scanning signal, and according to the scanning signal The patient is scanned, the control device is additionally operable to receive scanning result and determine the trouble according to the scanning result Each position dose of radiation Residual dose in person's body;
Computing device, radiation agent total amount is taken for calculating each position measurement Residual dose of the destination object with destination object Ratio, obtains each position measurement Residual dose residual activity of destination object;
Reference data device, for obtaining destination object whole body Residual dose distribution map, the destination object whole body residual agent point Butut includes that each position distribution Residual dose of destination object accounts for destination object whole body distribution Residual dose weight, and destination object Each position is distributed Residual dose ratio;
Means for correcting, for correcting each position measurement Residual dose of the destination object, makes each position measurement residual of destination object Dose ratio relation and each position distribution Residual dose ratio of destination object are consistent, obtain each position correction residual agent of destination object Amount;And
Analytical equipment, for calculating each position of destination object correction Residual dose total amount, to take radiation agent with destination object total The ratio of amount, obtains destination object whole body correction Residual dose residual activity.
8. dose of radiation Residue Monitoring system according to claim 7, it is characterised in that the detection device includes:It is accurate Straight device and linear array detector;Wherein,
The collimater is provided with multiple passages, is used to receive the ray of transmitting in patient's body;
The linear array detector includes multiple probe units, also, each probe unit is corresponded with each passage and set Put, each probe unit is used to receive and process the ray of the passage transmission, and output digit signals;
The control device is electrically connected with the probe unit, for receiving the data signal, and according to the data signal Determine patient's Radioimmunoimaging residual distribution.
9. dose of radiation Residue Monitoring system according to claim 7, it is characterised in that the height detection device is many It is individual and be arranged side by side.
10. dose of radiation Residue Monitoring system according to claim 7, it is characterised in that the height detection device is Ultrasonic detection device.
11. dose of radiation Residue Monitoring systems according to claim 7, it is characterised in that also include:Display;Wherein,
The display is electrically connected with the control device, and the dose of radiation for showing the patient remains distribution.
The 12. dose of radiation Residue Monitoring system according to any one of claim 7 to 11, it is characterised in that the branch Support body includes:Support body and top board;Wherein,
The first end of the support body is connected with the base, and the second end of the support body is connected with the top board Connect, the top board is oppositely arranged with the base;
The height detection device is installed on the top board;The lowering or hoisting gear is installed on the support body.
13. dose of radiation Residue Monitoring systems according to claim 12, it is characterised in that the lowering or hoisting gear includes: Drive mechanism, guide rail, connecting plate, sliding block and chain;Wherein,
The guide rail is set along the short transverse of the support body, and the sliding block is connected with the slide;
The input of the drive mechanism is electrically connected with the control device, and output end is connected with the chain, the driving Mechanism is used to receive the drive signal, and drives the chain to move up and down according to the drive signal;
The chain is connected by the connecting plate with the sliding block, for driving the connecting plate by initial sweep position Put and be moved to the terminal scan position;
The detection device is installed on the connecting plate.
14. dose of radiation Residue Monitoring systems according to claim 13, it is characterised in that the drive mechanism is driving Motor.
The 15. dose of radiation Residue Monitoring system according to any one of claim 7 to 11, it is characterised in that also include: Two handles;Wherein,
Two handles are mounted on the supporter and are placed in the both sides of the supporter.
CN201611069864.4A 2016-11-28 2016-11-28 A kind of dose of radiation residual activity value monitoring method and system Active CN106772529B (en)

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