CN106729616A - A kind of Western medicine compound for treating obesity - Google Patents
A kind of Western medicine compound for treating obesity Download PDFInfo
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- CN106729616A CN106729616A CN201611101762.6A CN201611101762A CN106729616A CN 106729616 A CN106729616 A CN 106729616A CN 201611101762 A CN201611101762 A CN 201611101762A CN 106729616 A CN106729616 A CN 106729616A
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Abstract
The invention discloses a kind of Western medicine compound for treating obesity, including following weight fraction raw material：10 15 parts of soyabean protein powder, 5 15 parts of sesame oil, 15 parts of acetylsalicylic acid, 5 10 parts of linoleic acid, 35 parts of leukotrienes, 0.01 0.1 parts of vitamin A, 0.01 0.1 parts of bata-carotene, 0.01 0.1 parts of vitamin D, 0.01 0.1 parts of vitamin B1,0.01 0.1 parts of vitamin B2,0.01 0.1 parts of nicotinic acid, 0.01 0.1 parts of vitamin C, 25 parts of xylitol, 58 parts of tartaric acid, 25 parts of promethazine hydrochloride piece.The Western medicine compound can obviously reduce body weight and food ration, reduce blood plasma HbA1c, LDL and TG level, suppress blood glucose rise, suppresses adipose tissue HMGB1 expression and declines, raising HDL levels；Also have the advantages that preparation method is simple, curative effect is short, instant effect, toxic and side effect it is small.
Description
Technical field
The present invention relates to a kind of technical field of western medicines, specifically a kind of Western medicine compound for treating obesity.
Background technology
Obesity is a kind of chronic metabolic disease caused by many factors, with the volume and cell of body fat cell
The percentage that number increases cause body fat percentage of liveweight increases and with the characteristics of some local excessive deposition fat extremely.Simple obesity is suffered from
Person's TBF is distributed than more uniform, does not have endocrine disturbance phenomenon, and also without dysbolism disease, often there is obesity in its family
Medical history.
The treatment of current obesity patient generally uses following methods：1) it is appropriate to lower meals heat.Intake heat is less than
Consumption of calorie, body fat is progressively decomposed during negative balance, and body weight progressively declines；2) replace high heat food with low calorie foods, use poultry
Meat, lean meat replace fat meat.Replace the dessert that sugar is more, oil is big with egg, milk, bean product.Chocolate, cream ice cream, candy
Should not eat；3) vegetables, beans, bean product etc. are increased while the food that sugar is more, oil is big, calorific value is high is reduced；Stem class vegetables are such as
Celery, rape, pakchoi；Melon vegetables such as wax gourd, cucurbita pepo etc.；4) pay the utmost attention to cut down staple food.Staple food is eaten as fat meat
Obtaining excessively can all cause simple obesity；5) food that sugar is more, oil is big, nutritive value is not high is gradually reduced, such as dessert, fried
Snack, western fast food, sweet drink etc.；6) various vitamins are supplemented.Do not eaten when TV is seen.No drinking；7) exercising with oxygen,
Such as walking, jog, aerobic behaviour, dancing, cycling, swimming, rope skipping, stair climbing；8) healthy lifestyles are set up, rationally
Nutrition, actively takes exercise, sufficient sleep, is good at adjusting psychological pressure, keeps setting the mind at rest；Non-smoking, do not take drugs, do not indulge in excessive drinking.
But not only curative effect is long for above-mentioned treatment method, slowly effect, and Most patients can not adhere to getting off, and delay
The state of an illness, therefore, the present invention provides a kind of compound Western medicine preparation that can effectively treat obesity, and not only curative effect is short, instant effect,
It is safe and toxic and side effect is small.
The content of the invention
It is an object of the invention to provide a kind of Western medicine compound for treating obesity, to solve above-mentioned background technology
The problem of middle proposition.
To achieve the above object, the present invention provides following technical scheme：
A kind of Western medicine compound for treating obesity, including following weight fraction raw material：Soyabean protein powder 10-15
Part, sesame oil 5-15 parts, acetylsalicylic acid 1-5 parts, linoleic acid 5-10 parts, leukotrienes 3-5 parts, vitamin A 0.01-0.1 parts, β-Hu
0.01-0.1 parts of radish element, vitamin D 0.01-0.1 parts, vitamin B1 0.01-0.1 parts, vitamin B2 0.01-0.1 parts, dimension
Raw 0.01-0.1 parts of element PP, vitamin C 0.01-0.1 parts, xylitol 2-5 parts, tartaric acid 5-8 parts, promethazine hydrochloride piece 2-5
Part.
As further scheme of the invention：Raw material including following weight fraction：12 parts of soyabean protein powder, sesame oil 8
Part, 2 parts of acetylsalicylic acid, 6 parts of linoleic acid, 4 parts of leukotrienes, 0.05 part of vitamin A, 0.03 part of beta carotene, vitamin D 0.02
Part, 0.02 part of vitamin B1,0.03 part of vitamin B2,0.02 part of nicotinic acid, 0.02 part of vitamin C, 4.3 parts of xylitol,
6.2 parts of tartaric acid, 3.5 parts of promethazine hydrochloride piece.
A kind of preparation method for treating the Western medicine compound of obesity, concretely comprises the following steps：
(1) taken in desinfection chamber vitamin A, beta carotene, vitamin D, vitamin B1, vitamin B2, nicotinic acid,
Vitamin C is ground well 10-15 minutes in being added to nonmetallic mortar, and closed black out is saved backup；
(2) in desinfection chamber, take during linoleic acid, leukotrienes are added to above-mentioned nonmetallic mortar and grind well 1-3 minutes, it is closed to close
Light is saved backup；
(3) in desinfection chamber, take tartaric acid and grind well 1-3 minutes during acetylsalicylic acid is added to above-mentioned nonmetallic mortar, it is closed
Black out is saved backup；
(4) in desinfection chamber, promethazine hydrochloride piece is put into after frying 1-2min in sesame oil and is taken out, cooling is standby；
(5) the promethazine hydrochloride piece after will be fried is put into above-mentioned nonmetallic mortar and is ground well 1-3 minutes, and closed black out is protected
Deposit standby；
(6) in desinfection chamber, take during soyabean protein powder, xylitol are added to above-mentioned nonmetallic mortar and mix, and be pressed into
0.1-1 grams of piece, grain, ball, gets product.
Compared with prior art, the beneficial effects of the invention are as follows：
First, the Western medicine compound has preferable therapeutic effect in terms of obesity is treated, and can obviously reduce body weight and takes the photograph
Appetite, reduces blood plasma HbA1c, LDL and TG level, suppresses blood glucose rise, suppresses adipose tissue HMGB1 expression and declines, and raises HDL
Level, is a kind of medicine for safely and effectively treating obesity；
2nd, raw material is easy to get, and cost of material is low, and preparation method is simple, is conducive to marketing；
3rd, application method is simple, and user need not move and go on a diet, it is easier to adhere to, and curative effect is short, instant effect,
It is safe and toxic and side effect is small.
Specific embodiment
The technical scheme of this patent is described in more detail with reference to specific embodiment.
Embodiment 1
A kind of Western medicine compound for treating obesity, including following weight fraction raw material：10 parts of soyabean protein powder,
5 parts of sesame oil, 1 part of acetylsalicylic acid, 5 parts of linoleic acid, 3 parts of leukotrienes, 0.01 part of vitamin A, 0.01 part of beta carotene, vitamin
0.01 part of D, 0.01 part of vitamin B1,0.01 part of vitamin B2,0.01 part of nicotinic acid, 0.01 part of vitamin C, xylose
2 parts of alcohol, 5 parts of tartaric acid, 2 parts of promethazine hydrochloride piece.
A kind of preparation method for treating the Western medicine compound of obesity, concretely comprises the following steps：
(1) taken in desinfection chamber vitamin A, beta carotene, vitamin D, vitamin B1, vitamin B2, nicotinic acid,
Vitamin C is ground well 10 minutes in being added to nonmetallic mortar, and closed black out is saved backup；(2) in desinfection chamber, take linoleic acid,
Leukotrienes is ground well 1 minute in being added to above-mentioned nonmetallic mortar, and closed black out is saved backup；(3) in desinfection chamber, tartaric acid is taken
It is added in above-mentioned nonmetallic mortar with acetylsalicylic acid and is ground well 1 minute, closed black out is saved backup；(4) in desinfection chamber, by hydrochloric acid
Fenazil piece fries taking-up after 1min in being put into sesame oil, and cooling is standby；(5) the promethazine hydrochloride piece after will be fried is put into
State and grind well 1 minute in nonmetallic mortar, closed black out is saved backup；(6) in desinfection chamber, soyabean protein powder, xylitol are taken and is added
Enter in above-mentioned nonmetallic mortar mixing, and be pressed into 0.1 gram of piece, grain, ball, get product.
Embodiment 2
A kind of Western medicine compound for treating obesity, including following weight fraction raw material：15 parts of soyabean protein powder,
15 parts of sesame oil, 5 parts of acetylsalicylic acid, 10 parts of linoleic acid, 5 parts of leukotrienes, 0.1 part of vitamin A, 0.1 part of beta carotene, vitamin
0.1 part of D, 0.1 part of vitamin B1,0.1 part of vitamin B2,0.1 part of nicotinic acid, 0.1 part of vitamin C, 5 parts of xylitol,
8 parts of tartaric acid, 5 parts of promethazine hydrochloride piece.
A kind of preparation method for treating the Western medicine compound of obesity, concretely comprises the following steps：
(1) taken in desinfection chamber vitamin A, beta carotene, vitamin D, vitamin B1, vitamin B2, nicotinic acid,
Vitamin C is ground well 15 minutes in being added to nonmetallic mortar, and closed black out is saved backup；(2) in desinfection chamber, take linoleic acid,
Leukotrienes is ground well 3 minutes in being added to above-mentioned nonmetallic mortar, and closed black out is saved backup；(3) in desinfection chamber, tartaric acid is taken
It is added in above-mentioned nonmetallic mortar with acetylsalicylic acid and is ground well 3 minutes, closed black out is saved backup；(4) in desinfection chamber, by hydrochloric acid
Fenazil piece fries taking-up after 2min in being put into sesame oil, and cooling is standby；(5) the promethazine hydrochloride piece after will be fried is put into
State and grind well 3 minutes in nonmetallic mortar, closed black out is saved backup；(6) in desinfection chamber, soyabean protein powder, xylitol are taken and is added
Enter in above-mentioned nonmetallic mortar mixing, and be pressed into 1 gram of piece, grain, ball, get product.
Embodiment 3
A kind of Western medicine compound for treating obesity, including following weight fraction raw material：12 parts of soyabean protein powder,
8 parts of sesame oil, 2 parts of acetylsalicylic acid, 6 parts of linoleic acid, 4 parts of leukotrienes, 0.05 part of vitamin A, 0.03 part of beta carotene, vitamin
0.02 part of D, 0.02 part of vitamin B1,0.03 part of vitamin B2,0.02 part of nicotinic acid, 0.02 part of vitamin C, xylose
4.3 parts of alcohol, 6.2 parts of tartaric acid, 3.5 parts of promethazine hydrochloride piece.
A kind of preparation method for treating the Western medicine compound of obesity, concretely comprises the following steps：
(1) taken in desinfection chamber vitamin A, beta carotene, vitamin D, vitamin B1, vitamin B2, nicotinic acid,
Vitamin C is ground well 12 minutes in being added to nonmetallic mortar, and closed black out is saved backup；(2) in desinfection chamber, take linoleic acid,
Leukotrienes is ground well 2 minutes in being added to above-mentioned nonmetallic mortar, and closed black out is saved backup；(3) in desinfection chamber, tartaric acid is taken
It is added in above-mentioned nonmetallic mortar with acetylsalicylic acid and is ground well 2 minutes, closed black out is saved backup；(4) in desinfection chamber, by hydrochloric acid
Fenazil piece fries taking-up after 1.5min in being put into sesame oil, and cooling is standby；(5) the promethazine hydrochloride piece after will be fried is put into
Ground well in above-mentioned nonmetallic mortar 2 minutes, closed black out is saved backup；(6) in desinfection chamber, soyabean protein powder, xylitol are taken
It is added in above-mentioned nonmetallic mortar and mixes, and be pressed into 0.6 gram of piece, grain, ball, gets product.
Embodiment 4
A kind of Western medicine compound for treating obesity, including following weight fraction raw material：14 parts of soyabean protein powder,
10 parts of sesame oil, 4 parts of acetylsalicylic acid, 8 parts of linoleic acid, 4 parts of leukotrienes, 0.5 part of vitamin A, 0.6 part of beta carotene, vitamin D
0.5 part, 0.5 part of vitamin B1,0.5 part of vitamin B2,05 part of nicotinic acid, 0.5 part of vitamin C, 4 parts of xylitol, wine
Stone acid 7 parts, 4 parts of promethazine hydrochloride piece.
A kind of preparation method for treating the Western medicine compound of obesity, concretely comprises the following steps：
(1) taken in desinfection chamber vitamin A, beta carotene, vitamin D, vitamin B1, vitamin B2, nicotinic acid,
Vitamin C is ground well 14 minutes in being added to nonmetallic mortar, and closed black out is saved backup；(2) in desinfection chamber, take linoleic acid,
Leukotrienes is ground well 2.5 minutes in being added to above-mentioned nonmetallic mortar, and closed black out is saved backup；(3) in desinfection chamber, winestone is taken
Acid and acetylsalicylic acid are ground well 2.5 minutes in being added to above-mentioned nonmetallic mortar, and closed black out is saved backup；(4) in desinfection chamber, will
Promethazine hydrochloride piece fries taking-up after 1.9min in being put into sesame oil, and cooling is standby；(5) the promethazine hydrochloride piece after will be fried is put
Enter in above-mentioned nonmetallic mortar to grind well 2.5 minutes, closed black out is saved backup；(6) in desinfection chamber, take soyabean protein powder,
Xylitol is mixed in being added to above-mentioned nonmetallic mortar, and is pressed into 0.8 gram of piece, grain, ball, is got product.
Comparative example 1
A kind of Western medicine compound for treating obesity, including following weight fraction raw material：12 parts of soyabean protein powder,
8 parts of sesame oil, 2 parts of acetylsalicylic acid, 6 parts of linoleic acid, 4 parts of leukotrienes, 0.05 part of vitamin A, 0.03 part of beta carotene, vitamin
0.02 part of D, 0.02 part of vitamin B1,0.03 part of vitamin B2,0.02 part of nicotinic acid, 0.02 part of vitamin C, xylose
4.3 parts of alcohol, 6.2 parts of tartaric acid, 1.5 parts of promethazine hydrochloride piece.
A kind of preparation method for treating the Western medicine compound of obesity, concretely comprises the following steps：
(1) taken in desinfection chamber vitamin A, beta carotene, vitamin D, vitamin B1, vitamin B2, nicotinic acid,
Vitamin C is ground well 12 minutes in being added to nonmetallic mortar, and closed black out is saved backup；(2) in desinfection chamber, take linoleic acid,
Leukotrienes is ground well 2 minutes in being added to above-mentioned nonmetallic mortar, and closed black out is saved backup；(3) in desinfection chamber, tartaric acid is taken
It is added in above-mentioned nonmetallic mortar with acetylsalicylic acid and is ground well 2 minutes, closed black out is saved backup；(4) in desinfection chamber, by hydrochloric acid
Fenazil piece fries taking-up after 1.5min in being put into sesame oil, and cooling is standby；(5) the promethazine hydrochloride piece after will be fried is put into
Ground well in above-mentioned nonmetallic mortar 2 minutes, closed black out is saved backup；(6) in desinfection chamber, soyabean protein powder, xylitol are taken
It is added in above-mentioned nonmetallic mortar and mixes, and be pressed into 0.6 gram of piece, grain, ball, gets product.
Comparative example 2
A kind of Western medicine compound for treating obesity, including following weight fraction raw material：12 parts of soyabean protein powder,
8 parts of sesame oil, 2 parts of acetylsalicylic acid, 6 parts of linoleic acid, 4 parts of leukotrienes, 0.05 part of vitamin A, 0.03 part of beta carotene, vitamin
0.02 part of D, 0.02 part of vitamin B1,0.03 part of vitamin B2,0.02 part of nicotinic acid, 0.02 part of vitamin C, xylose
4.3 parts of alcohol, 6.2 parts of tartaric acid, 0.5 part of promethazine hydrochloride piece.
A kind of preparation method for treating the Western medicine compound of obesity, concretely comprises the following steps：
(1) taken in desinfection chamber vitamin A, beta carotene, vitamin D, vitamin B1, vitamin B2, nicotinic acid,
Vitamin C is ground well 12 minutes in being added to nonmetallic mortar, and closed black out is saved backup；(2) in desinfection chamber, take linoleic acid,
Leukotrienes is ground well 2 minutes in being added to above-mentioned nonmetallic mortar, and closed black out is saved backup；(3) in desinfection chamber, tartaric acid is taken
It is added in above-mentioned nonmetallic mortar with acetylsalicylic acid and is ground well 2 minutes, closed black out is saved backup；(4) in desinfection chamber, by hydrochloric acid
Fenazil piece fries taking-up after 1.5min in being put into sesame oil, and cooling is standby；(5) the promethazine hydrochloride piece after will be fried is put into
Ground well in above-mentioned nonmetallic mortar 2 minutes, closed black out is saved backup；(6) in desinfection chamber, soyabean protein powder, xylitol are taken
It is added in above-mentioned nonmetallic mortar and mixes, and be pressed into 0.6 gram of piece, grain, ball, gets product.
The influence of experimental example 1 Western medicine compound to obesity mice
1.1 experiment materials
Experimental facilities：Glycosylated hemoglobin determines kit；HDL (HDL) kit, low-density lipoprotein
(LDL) kit and cruel (TG) kit of glycerine three；
Experimental animal：Ob/ob mouse, male 50,10 week old, body weight 55-60g.
1.2 experimental techniques
50 ob/ob mouse are randomly divided into 4 groups, i.e. model group, 3 groups of embodiment, 1 group of comparative example, 2 groups of comparative example, separately
Take 10 normal ob/ob mouse as a control group outward.Model group gives physiological saline gavage；3 groups of embodiment gives embodiment 3 and makes
Standby Western medicine compound gavage；1 group of comparative example gives the Western medicine compound gavage of the preparation of comparative example 1；2 groups of comparative example gives and contrasts
Western medicine compound gavage prepared by example 2, successive administration 5 weeks.
After 5 weeks, food ration is weighed and calculated to each group mouse, determined glycosylated hemoglobin (HbAlc), blood sugar, height
Density lipoprotein (HDL), low-density lipoprotein (LDL) and glycerine three are cruel (TG).Take adipose tissue, homogenate, the examination of BCA protein determinations
After agent box determines protein concentration, taking 50ug sample proteins carries out 10% dodecyl sodium sulfate polypropylene phthalein amine (SDS-PAGE)
Gel denaturing electrophoretic and then polyvinylidene fluoride (PVDF) film is gone to, adds HMGB1 primary antibodies, p-act in make internal reference,
Western blot detect the expression of adipose tissue HMGB1 albumen.Comparing carries out T between the difference of each administration group and model group, group
Inspection.
The Western medicine compound administration influence (n=10) to ob/ob mouse in 4 weeks of table 1
The 4 weeks blood biochemistry index on ob/ob mouse of Western medicine compound administration of table 2 influence (n=10)
Table 1,3 groups of embodiment of the result of table 2 display, 2 groups of comparative example, 1 group of comparative example substantially lose weight and food ration, reduce
Blood plasma HbA1c, LDL and TG level, suppresses blood glucose rise, suppresses adipose tissue HMGB1 expression and declines, raising HDL levels.Implement
3 groups of example is more obvious than 2 groups of comparative example, the therapeutic effect of 1 group of comparative example, with the increase of promethazine hydrochloride tablet amounts, therapeutic effect
It is better, therefore, the Western medicine compound is a kind of medicine for safely and effectively treating obesity.
The Western medicine compound has advantages below：
First, the Western medicine compound has preferable therapeutic effect in terms of obesity is treated, and can obviously reduce body weight and takes the photograph
Appetite, reduces blood plasma HbA1c, LDL and TG level, suppresses blood glucose rise, suppresses adipose tissue HMGB1 expression and declines, and raises HDL
Level, is a kind of medicine for safely and effectively treating obesity；
2nd, raw material is easy to get, and cost of material is low, and preparation method is simple, is conducive to marketing；
3rd, application method is simple, and user need not move and go on a diet, it is easier to adhere to, and curative effect is short, instant effect,
It is safe and toxic and side effect is small.
The better embodiment to this patent is explained in detail above, but this patent is not limited to above-mentioned embodiment party
Formula, in the ken that one skilled in the relevant art possesses, can also be on the premise of this patent objective not be departed from
Make a variety of changes.
Claims (3)
1. a kind of Western medicine compound for treating obesity, it is characterised in that the raw material including following weight fraction：Soybean egg
White powder 10-15 parts, sesame oil 5-15 parts, acetylsalicylic acid 1-5 parts, linoleic acid 5-10 parts, leukotrienes 3-5 parts, vitamin A 0.01-
0.1 part, beta carotene 0.01-0.1 parts, vitamin D 0.01-0.1 parts, vitamin B1 0.01-0.1 parts, vitamin B2
0.01-0.1 parts, nicotinic acid 0.01-0.1 parts, vitamin C 0.01-0.1 parts, xylitol 2-5 parts, tartaric acid 5-8 parts, salt
2-5 parts of sour fenazil piece.
2. the Western medicine compound for treating obesity according to claim 1, it is characterised in that including following weight point
Several raw materials：12 parts of soyabean protein powder, 8 parts of sesame oil, 2 parts of acetylsalicylic acid, 6 parts of linoleic acid, 4 parts of leukotrienes, vitamin A 0.05
Part, 0.03 part of beta carotene, 0.02 part of vitamin D, 0.02 part of vitamin B1,0.03 part of vitamin B2, nicotinic acid
0.02 part, 0.02 part of vitamin C, 4.3 parts of xylitol, 6.2 parts of tartaric acid, 3.5 parts of promethazine hydrochloride piece.
3. a kind of preparation method of Western medicine compound for treating obesity as described in claim 1-2 is any, its feature
It is to concretely comprise the following steps：
(1) vitamin A, beta carotene, vitamin D, vitamin B1, vitamin B2, nicotinic acid, dimension life are taken in desinfection chamber
Plain C is ground well 10-15 minutes in being added to nonmetallic mortar, and closed black out is saved backup；
(2) in desinfection chamber, take during linoleic acid, leukotrienes are added to above-mentioned nonmetallic mortar and grind well 1-3 minutes, closed black out is protected
Deposit standby；
(3) in desinfection chamber, take tartaric acid and grind well 1-3 minutes during acetylsalicylic acid is added to above-mentioned nonmetallic mortar, closed black out
Save backup；
(4) in desinfection chamber, promethazine hydrochloride piece is put into after frying 1-2min in sesame oil and is taken out, cooling is standby；
(5) the promethazine hydrochloride piece after will be fried is put into above-mentioned nonmetallic mortar and is ground well 1-3 minutes, and closed black out preserves standby
With；
(6) in desinfection chamber, take during soyabean protein powder, xylitol are added to above-mentioned nonmetallic mortar and mix, and be pressed into 0.1-1
Gram piece, grain, ball, get product.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1212605A (en) * | 1996-02-29 | 1999-03-31 | 纳特里制药股份有限公司 | Composition and its use as food supplement or for lowering lipids in serum |
| CN102106498A (en) * | 2010-12-28 | 2011-06-29 | 北京康比特体育科技股份有限公司 | Weight losing meal-replacing powder |
| CN105998615A (en) * | 2016-06-13 | 2016-10-12 | 李凤 | Traditional Chinese medicine composition for treating obesity |
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2016
- 2016-12-05 CN CN201611101762.6A patent/CN106729616A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1212605A (en) * | 1996-02-29 | 1999-03-31 | 纳特里制药股份有限公司 | Composition and its use as food supplement or for lowering lipids in serum |
| CN102106498A (en) * | 2010-12-28 | 2011-06-29 | 北京康比特体育科技股份有限公司 | Weight losing meal-replacing powder |
| CN105998615A (en) * | 2016-06-13 | 2016-10-12 | 李凤 | Traditional Chinese medicine composition for treating obesity |
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| 《药学服务指南丛书》编委会: "《非处方药使用手册》", 30 April 2005, 群言出版社 * |
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Application publication date: 20170531 |