CN106729433B - 一种治疗皮肤痈肿的中药复方及其制剂 - Google Patents

一种治疗皮肤痈肿的中药复方及其制剂 Download PDF

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CN106729433B
CN106729433B CN201710041332.8A CN201710041332A CN106729433B CN 106729433 B CN106729433 B CN 106729433B CN 201710041332 A CN201710041332 A CN 201710041332A CN 106729433 B CN106729433 B CN 106729433B
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张灵金
左志琴
刘矗
沈志华
游敏玲
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Shenzhen City Luohu District Chinese Medicine Hospital
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Abstract

本发明涉及医药领域，提供了一种治疗皮肤痈肿的中药复方及其制剂，本方由丹参10‑30g、天花粉10‑30g、大黄10‑20g、黄柏10‑20g、姜黄10‑20g、白芷10‑30g、夏枯草10‑20g、赤芍10‑20g、香附10‑20g、三棱10‑20g、莪术10‑20g、南星(制)5‑10g、冰片2‑5g、甘草5‑10g。皮肤痈肿是皮肤科常见感染性疾病，往往从早期开始就需大量使用抗生素，后期需手术切开排脓，中医认为其病机为热毒壅盛，气血凝聚，运用本方制剂外敷或内服，可快速消除皮肤红肿，尤其是早期使用，无需抗生素，无需手术治疗，有效率达95％以上，适应于所有人群。

Description

一种治疗皮肤痈肿的中药复方及其制剂
技术领域
本发明涉及医药领域，提供了一种治疗皮肤痈肿的中药复方及其制剂。
背景技术
皮肤痈肿是一种由多个临近毛囊的深部感染引起的易化脓性皮肤病，常伴有发热、畏寒、头痛、食欲不振等全身症状，严重者可继发毒血症、败血症导致死亡。其病因中医认为过食辛燥食物，以致脾胃蕴结热毒，加之风热邪毒侵犯皮肤使热毒壅盛，气血凝聚而发生此病。患者初起为弥漫性浸润性紫红斑，范围可达10厘米或更大，表面紧张发亮，触痛明显，之后局部出现多个脓头，有较多脓栓和血性分泌物排出，可有组织坏死和溃疡形成，甚至形成窦道，局部淋巴结肿大，常伴有发热、畏寒、头痛、食欲不振等全身症状。往往从早期开始就需大量使用抗生素，后期需手术切开排脓。
现有技术CN103142730A提供了一种中药内服外用的方法，治疗皮肤痈肿，具体地是指皮肤痈肿颗粒和外敷粉剂的制作方法。(一)内服皮肤痈肿颗粒，主要成分和配比为：穿山甲8％、栀子6％、连翘10％、黄连6％、黄芩6％、白芷6％、天花粉8％、皂角刺8％、归尾8％、甘草5％、赤芍4％、金银花15％、大黄4％、芒硝6％。
现有技术CN103142730A提供了一种治疗皮肤痈肿的中药制剂，由如下重量份的原料药制成：秦皮23-27份、野菊花23-27份、玄参23-27份、生地黄23-27份、草决明23-27份、大黄13-17份、黄芩8-12份、牛膝8-12份、黄连8-12份、枳实8-12份、牡丹皮8-12份、天花粉8-12份、蝉蜕3-7份、甘草3-7份。
现有技术多以辛凉解表清热药如菊花、栀子和金银花等为君药，治疗皮肤痈肿的效果还带进一步改善。
发明内容
鉴于现有技术存在的问题，本发明根据皮肤痈肿的中医病机-热毒壅盛、气血凝聚，提供了一种治疗皮肤痈肿的中药复方及其制剂，运用本方外敷或内服，可快速消除皮肤痈肿，无需要手术治疗，有效率达95％以上，尤其是早期皮肤痈肿，适应于所有人群。
具体的，本发明首要目的在于提供了一种治疗皮肤痈肿的中药复方，组成为丹参10-30g、天花粉10-30g、大黄10-20g、黄柏10-20g、姜黄10-20g、白芷10-30g、夏枯草10-20g、赤芍10-20g、香附10-20g、三棱10-20g、莪术10-20g、南星(制)5-10g、冰片2-5g、甘草5-10g。
功用：清热解毒，消肿散结，活血止痛。
主治：由热毒壅聚，气滞血瘀痰结所致痈疮肿毒之阳证、半阴半阳证，初期能促进消退，化脓期促进排脓。
方解：方中丹参味苦，微寒，具有活血祛瘀，凉血消痈之功，天花粉性甘、微苦，微寒，具有清热泻火，消肿排脓之功，两者配伍，清热排脓、消肿止痛，故重用为君药。大黄苦，寒，清热泻火，凉血解毒；黄柏：味苦，性寒，清热燥湿，解毒疗疮；夏枯草辛、苦，寒，清热泻火，散结消肿；姜黄：辛苦，温，破血，行气，止痛；白芷：辛，温，祛风，燥湿，消肿，止痛；共凑清热澡湿、辛温透邪，消肿止痛，以助君用，为臣药。赤芍味苦，性微寒，清热凉血，活血祛瘀的功效，与天花粉、丹参同用，可用于热毒壅盛，痈肿疮疡；香附辛、微苦、微甘，平，理气止痛，三棱、莪术破血行气，消积止痛，三棱辛、苦，平治血中之气，莪术：辛、苦，温，治气中之血，可以加强姜黄理气止痛之功；天南星，性味：苦、辛，温，散结消肿止痛；冰片：辛苦，凉，通诸窍，散郁火；共为使药。甘草解天南星之毒，并调和诸药。诸药合用，共奏清热解毒，散结袪瘀，消肿止痛之功。使热毒得解，瘀结得散，湿毒得化，肿痛自消。
本发明的另一目的在于提供了一种治疗皮肤痈肿的中药复方制剂，具体地，本方可制成中医膏剂、散剂外敷，亦可作为汤剂内服。
本发明相对于现有技术的效果包括：
现有技术未见本发明的复方组方报道，根据前述方解，本发明依靠各药物的性能，依照君臣佐使原则，实现了方剂各组方药物的协同作用效果，采用本发明的复方积极制剂可快速消除皮肤痈肿，无需要手术治疗，有效率达95％以上。
具体实施方式
下面结合实施例对本发明及其有效的技术效果作进一步详细的描述，但发明的实施方式不限于此。
实施例1
一种治疗皮肤痈肿的中药复方，组成为丹参20g、天花粉20g、大黄15g、黄柏15g、姜黄15g、白芷20g、夏枯草15g、赤芍15g、香附15g、三棱15g、莪术15g、南星(制)7.5g、冰片3.5g、甘草7.5g。
实施例2
一种治疗皮肤痈肿的中药复方，组成为丹参30g、天花粉30g、大黄20g、黄柏20g、姜黄20g、白芷30g、夏枯草20g、赤芍20g、香附20g、三棱20g、莪术20g、南星(制)10g、冰片5g、甘草10g。
实施例3
采用实施例1的方剂，做汤剂煎汤内服，煎汤可根据常规中药制剂制备方法，例如，采用铁制容器，加水要没过药物大约10厘米,最好先浸泡30分钟，先用武火煮沸后，改用文火慢煎40-60分钟，煎汤2-3次后合并，适合一日服用3次剂量。
实施例4
采用实施例2的方剂，本方可根据常规中药制剂制备方法制成中医膏剂、散剂外敷。
实施例5
临床效果：采用本发明的复方及其制剂可快速消除皮肤痈肿，尤其是早期使用，无需抗生素，无需手术治疗，有效率达95％以上。
以上内容是结合具体的优选实施方式对本发明所作的进一步详细说明，不能认定本发明的具体实施只局限于这些说明。对于本发明所属技术领域的普通技术人员来说，在不脱离本发明构思的前提下，还可以做出若干简单推演或替换，都应当视为属于本发明的保护范围。

Claims (4)

1.一种内服治疗皮肤痈肿的中药复方，其特征在于，原料药为丹参10-30g、天花粉10-30g、大黄10-20g、黄柏10-20g、姜黄10-20g、白芷10-30g、夏枯草10-20g、赤芍10-20g、香附10-20g、三棱10-20g、莪术10-20g、制南星5-10g、冰片2-5g、甘草5-10g。
2.一种治疗皮肤痈肿的中药复方制剂，其特征在于，采用权利要求1所述的复方，制成汤剂内服。
3.权利要求1所述的复方在制备皮肤痈肿药物中的用途。
4.权利要求2所述的复方制剂在制备皮肤痈肿药物中的用途。
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