CN106729321A - 一种治疗非淋菌性尿道炎的中药方 - Google Patents
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Abstract
本发明公开了一种治疗非淋菌性尿道炎的中药方,包含以下组分:党参10‑40份、白术20‑50份、甘草20‑50份、当归20‑40份、熟地30‑45份、肉桂10‑30份、陈皮8‑18份、香附2‑12份、海螵蛸10‑35份、广木香10‑30份、沙仁22‑42份、浙贝20‑40份、荜茇30‑50份、神曲10‑30份、夏枯草20‑40份、山楂5‑20份,以上份数均为重量份数。本发明对于由衣原体、支原体感染导致的非淋菌性尿道炎有很好的治疗作用,临床总有效率达到90%,治愈率达到85%,临床用药安全,适用人群广泛,深受广大患者好评。
Description
技术领域
本发明涉及一种治疗非淋菌性尿道炎的中药。
背景技术
非淋菌性尿道炎是指由淋菌以外的其他病原体,主要是沙眼衣原体和支原体等引起的一种性传播疾病。在临床上有尿道炎的表现,但在分泌物中查不到淋球菌,细菌培养也无淋球菌生长。本病目前在欧美国家已超过淋病而跃居性传播疾病的首位,在我国日益增多,成为最常见的性传播疾病之一。
引起该病的主要病原体为沙眼衣原体占40-50%,其次为支原体占20-30%,其他病原体为阴道滴虫、单纯疱疹病毒、白色念珠菌、阴道嗜血杆菌及包皮杆菌等。
在临床中,支原体、衣原体属病原感染导致的非淋菌性尿道炎,其典型症状为尿道刺痒,伴有尿急、尿痛,有轻度或无排尿困难,尿道分泌物少或无,其尿急、尿痛症状比淋病来的轻。总之发病缓慢、症状轻、持续时间长是其临床特征。目前该病已经居性病的第一位。
该病可以引起多种并发症状,如:非淋菌性尿道球腺炎、非淋菌性急性、慢性前列腺炎、附睾炎以及精囊炎、尿道狭窄、Reiter综合症及女性尿道炎、宫颈炎、前庭大腺炎、急慢性盆腔炎、直肠炎,导致不孕不育症甚至感染或者遗传后代,不仅对于病患者本人及家庭,更是对国民素质提局构成极大的危害。已经成为全球性性传播疾病,发病率高,70年代以来已经成为欧美国家常见的传染病,比淋病性尿道炎的发病率高出两倍以上。
而在药物治疗中,由于衣原体、支原体病原体体积小,约300-400纳米,是介于细菌和病菌之间的微生物,一般的杀菌西药药物对其针对性不强或者由于局部血药浓度不够、局部药物作用时问不长、抗药病株的出现等原因,杀菌不彻底,所以造成顽固性复发及再感染,所以即使是对其作用相对显著的四环素类及大环内脂类抗生素也无法根治,最新的司中自沙星药物也由于副作用大,对人体脏器如肝肾破坏损伤而使适用人群、适用条件受到影响。
发明内容
本发明的目的在于提供一种治疗非淋菌性尿道炎的中药方。在于克服现有 技术中存在的缺陷而提供一种以祖国传统医学理论为基础,以中医药学的“热淋”范畴对照非淋菌性尿道炎的支原体、衣原体感染症状,附以现代的检査手段,精心配伍,攻克三焦郁热、气博于肾、外感菌株、流入膀胱,进而湿热下注造成非淋菌性尿道炎的中药,达到杀菌灭菌、标本兼治,疗效迅速、疗程短、治愈率高、复发率低、适用人群广、无副作用的目的。
为了达到以上目的,本发明采用的技术方案如下:
一种治疗非淋菌性尿道炎的中药方,其特征在于,包含以下组分:
党参10-40份、白术20-50份、甘草20-50份、当归20-40份、熟地30-45份、肉桂10-30份、陈皮8-18份、香附2-12份、海螵蛸10-35份、广木香10-30份、沙仁22-42份、浙贝20-40份、荜茇30-50份、神曲10-30份、夏枯草20-40份、山楂5-20份,以上份数均为重量份数。
本发明的上述药物组合物,按照常规的中药制剂工艺,可以制备成为任何一种常用内服药物剂型,如:丸剂(大密丸、水丸、浓缩丸)、散剂、片剂、胶囊、口服液等。
本发明中药方胶囊剂的制备方法是:将以上各种药物按照规定配比选取药材,凉水洗净,经沥水---晾晒---烘干,分别粉碎成粉木,混匀,过120目筛,分装入胶囊。胶囊规格为0.5g/粒。
有益效果:本发明药物具有滋阴清热、扶正固本、利湿通淋、杀菌祛邪、抗毒解毒、健脾滋肾的功效,对于由衣原体、支原体感染导致的非淋菌性尿道炎有很好的治疗作用,临床总有效率达到90%以上,治愈率达到85%以上,临床用药安全,适用人群广泛,深受广大患者好评。本发明不仅考虑外侵湿热之邪蕴积膀胱之标实,更考虑到肾精亏损之本虚,釆用扶正祛邪之法,使得扶正不恋邪,祛邪不伤正,进行科学配伍,经过临床总结及确切的疗效分析和西医检査手段的配合,反复筛选,化验认证,研制成本发明药物。
具体实施方式
实施例:一种治疗非淋菌性尿道炎的中药方,包含以下组分:
党参20份、白术30份、甘草30份、当归25份、熟地35份、肉桂25份、陈皮15份、香附10份、海螵蛸20份、广木香20份、沙仁30份、浙贝30份、荜茇35份、神曲20份、夏枯草25份、山楂15份,以上份数均为重量份数。
实验例:
从1998年12月至2016年12月,共治疗非淋菌性尿道炎患者6896例,男性4800例,女性2096例,年龄在16-70岁之间。其中衣原体感染4292例,支原体感染2504例,霉菌感染100例。病史最长24个月,最短1个月。都是经过西药治疗无效的病人。通过使用本发明的胶囊制剂进行临床治疗,取得满意的效果。(其中,6050人治愈801人有效、45人无效)
典型病例:
张xx,男,45岁,安徽合肥人,患非淋菌性尿道炎24个月,属于衣原体感染,采用西医抗菌素治疗,几乎没有任何效果,采用本发明的药方后,1个疗程偶尔还有尿道不适感,但化验检测衣原体、支原体为阴性。2个疗程后,尿道剌痒、灼热、灼痛、尿频尿急,有脓性或粘液性分泌物等症状完全消失,彻底治愈,之后再没有复发。
王x,女,23岁,江苏南京人,患非淋菌性尿道炎13个月,属于支原体感染,尿道刺痒,伴有尿急、尿痛,有轻度或无排尿困难,采用西医抗菌素治疗效果不明显,一旦停药就严重采用本发明的药方后,1个疗程偶尔还有尿道不适感,但化验检测衣原体、支原体为阴性。2个疗程后,尿道剌痒、灼热、灼痛、尿频尿急,有脓性或粘液性分泌物等症状完全消失,彻底治愈,之后再没有复发。
现总结如下:
临床资料:
1、病历选择标准:
根据卫生部防疫司规定的诊断标准选择病人。
(1)、1周内未用过任何治疗非淋菌性尿道炎的药物及其他抗菌素;
(2)、尿道局部有明显的尿道炎症状,尿道剌痒、灼热、灼痛、尿频尿急,有脓性或粘液性分泌物;
(3)、化验室检査衣原体、支原体阳性。
从1998年12月至2016年12月,共治疗非淋菌性尿道炎患者6896例,男性4800例,女性2096例,其中衣原体感染4292例,支原体感染2504例。
2、治疗方法及用药办法
以本发明的胶囊剂型规格为0.5g/粒,由阜阳市广宇男性病及不孕不育症研究所制备成科研用药,每次3粒,每日二次,用药15天为一个疗程,根据需要可以连续2-3个疗程。为了比较疗效,将同期应用西药治疗的病人作为对照组。
3、疗效标准及疗效分析
治愈:服药后临床症状全部消失,化验衣原体、支原体全部转阴。
显效:用药后临床症状基本消失,偶尔有尿道不适感,但化验检测衣原体、支原体为阴性。
无效:临床症状明显改善,但是化验检测衣原体、支原体仍为阳性。
4、治疗结果
临床观察结果表明,本发明的胶囊剂治疗非淋菌性尿道炎疗效高,见效快,无明显副作用,有效率高达90%以上,其疗效明显高于抗菌素治疗组。尤其是对于那些久治不愈、病情迁延的混合性感染患者,以及抗菌素耐药患者,经过2-3个疗程的治疗后,也均获得治愈。
本发明药方制成的胶囊剂与西药治疗非淋菌性尿道炎的疗效比较:
人数 | 治愈 | 显效 | 无效 | |
本发明药方 | 6896 | 6050 | 801 | 45 |
抗菌素 | 8984 | 4080 | 3200 | 1704 |
表1
以上表1中采用西药治疗非淋菌性尿道炎的数据来自合肥市第一人民医院泌尿科,该数据采用了阜阳市第一人民医院1998年12月至2016年12月的数据。
Claims (1)
1.一种治疗非淋菌性尿道炎的中药方,其特征在于,包含以下组分:
党参10-40份、白术20-50份、甘草20-50份、当归20-40份、熟地30-45份、肉桂10-30份、陈皮8-18份、香附2-12份、海螵蛸10-35份、广木香10-30份、沙仁22-42份、浙贝20-40份、荜茇30-50份、神曲10-30份、夏枯草20-40份、山楂5-20份,以上份数均为重量份数。
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