CN106729281A - For the Chinese medicine composition of children's enuresis nocturna - Google Patents

For the Chinese medicine composition of children's enuresis nocturna Download PDF

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CN106729281A
CN106729281A CN201611224750.2A CN201611224750A CN106729281A CN 106729281 A CN106729281 A CN 106729281A CN 201611224750 A CN201611224750 A CN 201611224750A CN 106729281 A CN106729281 A CN 106729281A
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parts
medicine composition
chinese medicine
chinese
enuresis
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何乃峰
张红燕
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Shandong University of Traditional Chinese Medicine
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Shandong University of Traditional Chinese Medicine
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9062—Alpinia, e.g. red ginger or galangal
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/57—Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/13—Coniferophyta (gymnosperms)
    • A61K36/14—Cupressaceae (Cypress family), e.g. juniper or cypress
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/43—Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage

Abstract

A kind of Chinese medicine composition for children's enuresis nocturna,Include Chinese medicine composition I and Chinese medicine composition II,Chinese medicine composition I is set to include cloves,Chinese cassia tree,Fructus alpiniae oxyphyllae and raspberry,Chinese medicine composition II is set to include intelligence development,Grass-leaved sweetflag,The seed of Oriental arborvitae,Cornu cerve degelatinatum,The root of herbaceous peony,Chinese ephedra,Thizoma curculiginis,Semen Cuscutae,Cassia twig,The membrane of a chicken's gizzard,Gingko and lopseed,By cloves,Chinese cassia tree,The effective ingredient of fructus alpiniae oxyphyllae and raspberry is permeated and intelligence development in SHENQUE acupoint,Grass-leaved sweetflag,The seed of Oriental arborvitae,Cornu cerve degelatinatum,The root of herbaceous peony,Chinese ephedra,Thizoma curculiginis,Semen Cuscutae,Cassia twig,The membrane of a chicken's gizzard,The absorption of the pharmaceutical compositions of gingko and lopseed,Realize tonifying kidney and the treatment by Chinese herbs principle for replenishing qi to invigorate the spleen,These drug regimens are caused that each efficacy of drugs produces synergy,So as to effectively treatment infantile enuresis,Therefore improve the therapeutic effect to infantile enuresis and do not produce side effect.

Description

For the Chinese medicine composition of children's enuresis nocturna
First, technical field
The present invention relates to a kind of Chinese medicine composition, especially a kind of Chinese medicine composition for children's enuresis nocturna.
2nd, background technology
Infantile enuresis refers to that children of the age more than five years old sleep middle incontinence of urine, a kind of disease that rear of waking up is felt.Due to morbidity Rate averagely accounts for the 2.3% -25% of pediatric population, and infantile enuresis is a kind of common disease of children, if can not treat in time, Great pressure can be caused to the psychology and spirit of infant, influence the physical and mental health of child and grow, existing Western medicine is controlled The medication effect for treating infantile enuresis is undesirable, easily recurs and can not effect a radical cure, and is also used for children's enuresis nocturna without a kind of Chinese medicine composition, so as to improve the symptom of children's enuresis nocturna.
Morbidity is not filled with vigour, and lung, spleen, renal dysfunction are relevant.It is divided into primary (primary nocturnal Enuresis PNE) and secondary enuresis（SNE), wherein since the childhood with regard to the enuresis, and in the absence of having urethral disease and continue to exist Bed wetter is referred to as primary enuresis.Secondary enuresis refers to that children can control urination at least 1 year, but after rear and the enuresis occur Person.According to whether with daytime symptoms（With urgent urination, frequent micturition, the urinary incontinence）, the monosymptom enuresis is divided into again（MNE) (not companion There are daytime symptoms）With the complexity enuresis（CNE).
Based on existing technical problem, technical characteristic and technique effect, application technical scheme of the invention is made.
3rd, the content of the invention
Object of the invention is a kind of Chinese medicine composition for children's enuresis nocturna.
In order to overcome above-mentioned technical disadvantages, it is an object of the invention to provide a kind of Chinese traditional medicine composition for children's enuresis nocturna Thing, therefore improve the therapeutic effect to infantile enuresis and do not produce secondary work.
To reach above-mentioned purpose, the present invention is adopted the technical scheme that：Include cloves, Chinese cassia tree, fructus alpiniae oxyphyllae and raspberry.
The present invention is devised, and includes Chinese medicine composition I and Chinese medicine composition II,
Chinese medicine composition I is set to include cloves, Chinese cassia tree, fructus alpiniae oxyphyllae and raspberry,
Chinese medicine composition II be set to include intelligence development, grass-leaved sweetflag, the seed of Oriental arborvitae, cornu cerve degelatinatum, the root of herbaceous peony, Chinese ephedra, thizoma curculiginis, Semen Cuscutae, Cassia twig, the membrane of a chicken's gizzard, gingko and lopseed.
Stated in theory of traditional Chinese medical science：The infantile enuresis cause of disease is generally asthenic symptoms, and children's internal organs are tender and lovely, and shape gas does not fill, or because of the day after tomorrow Lose and support, it is biochemical passive, or because native endowment is not good, kidney fire void declines, can not warm invigorating the spleen sun, such speen-kidney dificiency, and then lower unit The cold of insufficiency type, wing skin disturbance in functioning of QI, therefore see the enuresis, therefore principle of reatment be with tonifying kidney and replenish qi to invigorate the spleen, by cloves, Chinese cassia tree, The effective ingredient of fructus alpiniae oxyphyllae and raspberry is in SHENQUE acupoint infiltration and intelligence development, grass-leaved sweetflag, the seed of Oriental arborvitae, cornu cerve degelatinatum, the root of herbaceous peony, Chinese ephedra, celestial being The absorption of the pharmaceutical compositions of thatch, Semen Cuscutae, cassia twig, the membrane of a chicken's gizzard, gingko and lopseed, in realizing tonifying kidney and replenishing qi to invigorate the spleen These drug regimens are caused that each efficacy of drugs produces synergy such that it is able to effectively treat infantile enuresis by medicine principle of reatment, Therefore improve the therapeutic effect to infantile enuresis and do not produce side effect.
In the technical program, cloves, Chinese cassia tree, fructus alpiniae oxyphyllae and raspberry are set to monarch drug in a prescription, intelligence development, gingko, grass-leaved sweetflag, Tu Silk, the root of herbaceous peony and the membrane of a chicken's gizzard are set to ministerial drug, and cassia twig, Chinese cassia tree, the seed of Oriental arborvitae and lopseed are set to make medicine, Chinese ephedra, thizoma curculiginis and deer Angle frost is set to adjutant, by tonifying kidney and replenishing qi to invigorate the spleen, treats and improve infantile enuresis effect more preferable.
The present invention is devised, and is set to include Chinese medicine composition I and Chinese medicine composition II, according to ratio of weight and number,
Chinese medicine composition I is set to include cloves 10-16 parts, Chinese cassia tree 8-12 parts, fructus alpiniae oxyphyllae 20-23 parts and raspberry 2-3 parts,
Chinese medicine composition II is set to include intelligence development 7-9 parts, grass-leaved sweetflag 11-13 parts, seed of Oriental arborvitae 33-36 parts, cornu cerve degelatinatum 21-25 Part, root of herbaceous peony 4-6 parts, Chinese ephedra 10-14 parts, thizoma curculiginis 11-15 parts, Semen Cuscutae 6-8 parts, cassia twig 7-9 parts, the membrane of a chicken's gizzard 40-43 parts, gingko 2-6 parts and lopseed 20-24 parts.
The present invention is devised, and is set to include Chinese medicine composition I and Chinese medicine composition II, according to ratio of weight and number,
Chinese medicine composition I is set to include 3 parts of 14 parts of cloves, 12 parts of Chinese cassia tree, 20 parts of fructus alpiniae oxyphyllae and raspberry,
Chinese medicine composition II be set to include 9 parts of intelligence development, 12 parts of grass-leaved sweetflag, 36 parts of the seed of Oriental arborvitae, 23 parts of cornu cerve degelatinatum, 4 parts of the root of herbaceous peony, 23 parts of 12 parts of Chinese ephedra, 13 parts of thizoma curculiginis, 8 parts of Semen Cuscutae, 8 parts of cassia twig, 42 parts of the membrane of a chicken's gizzard, 5 parts of gingko and lopseed.
The property of medicine of the component in prescription of the invention：
Cloves is conventional Chinese medicine, is one of China's tradition import " southern medicine ", first recorded in《Haigoushen》, cloves contains volatile oil, in oil The composition such as main oleic acid containing cloves, acetyl cloves oleic acid and the positive heptanone of cloves alkene, MAK, methyl, vanillin.Tool suppression Bacterium and anthelmintic action, as fragrance, antispastic carminative treats the diseases such as stomach trouble, stomachache, vomiting, neuralgia, toothache.Cloves is not Only Medicinal plants, are also the rare spice berry in the world.
Chinese cassia tree（Classification system：Cinnamomum cassia Presl）, also known as beautiful osmanthus, male osmanthus, cajaput, great Gui, peppery osmanthus, Safety tree, cassia, are the dry bark of canella Chinese cassia tree, and cassia is stripped from stem and branch, are shelved after drying, curling In rolls.
Fructus alpiniae oxyphyllae Chinese medicine name, is zingiberaceous plant intelligence developmentAlpinia oxyphylla Miq. fruit.Be distributed in Guangdong and Also there is cultivation in Hainan, Fujian, Guangxi, Yunnan.Saliva is taken the photograph with warming spleen and stopping diarrha, the effect of warm up kidney contracting urine controlling nocturnal emission with astringent drugs, is usually used in taste empty It is cold, vomiting, diarrhea, crymodynia in abdomen, many salivas of mouth, enuresis with renal asthenia, frequent micturition, seminal emission, gonorrhoea.
Raspberry Chinese medicine name, is rosaceous plant rubus chingii HuRubus chingii The dry fruit of Hu.It is distributed in The ground such as Jiangsu, Zhejiang, Anhui, Fujian, Jiangxi, Guangxi.With supplementing the kidney to control the nocturnal contracting urine, the effect of nourishing the liver to improve visual acuity.It is usually used in seminal emission Involuntary emission, enuresis frequent micturition, impotence and premature ejaculation, mesh is secretly dim-sighted.
Intelligence development（Classification system：Alpinia oxyphylla Miq.）, alias：Fructus alpiniae oxyphyllae, intelligence development, Zingiber, Alpinia Herbaceos perennial.Plant height is up to 3 meters；Stem is grown thickly；Rhizome is short, and blade lanceolar, raceme is all contained in bud In a hat shape phyllary, entirely come off during flower, rachis is by extremely short pubescence；Calyx tubular, corolla white is outer to be dredged soft Hair；Lip obovate, white powder and have red veins, spherical when capsule is fresh, spindle when doing, seed is irregularly oblate, quilt Faint yellow aril, fruit ellipse, two ends are slightly sharp, surface brown or taupe brown, there is the rough projection in longitudinal direction.Pericarp is thin And it is tougher, it to be close to seed group, seed group is divided into 3 valves by barrier film, there is seed 6-11 per valve, and seed is in irregular oblate Shape, slightly wane, diameter about 3mm, surface taupe or lark, the outer aril by light brown film quality, 3~September of flowering fruit bearing stage.
Grass-leaved sweetflag（Classification system：Acorus tatarinowii）, category Araeceae, Acorus graminoid perennial herb Plant, its rhizome tool smell.Leaf full edge, lines up two row, spadix（Spadix）, bennet green, spathe is lobate.Rhizome Often make medicinal.The area of 20 meters to 2600 meters of height above sea level is grown on, is given birth in mountain stream water stone space or between the flowing water gravel of gully more （Sometimes it is very aquatic length）, the flowering fruit bearing stage 2-6 months.
Seed of Oriental arborvitae Chinese medicine name.It is cupressaceae plant arbor-vitaePlatycladus orientalis(L.) drying and ripening of Franco Benevolence, autumn, season in winter two harvesting mature seed, dries, and removes kind of a skin, collects benevolence, is born in moistening fertilely, lime rock ground There is growth, be distributed in THE SOUTH OF NORTHEAST CHINA, Guangdong, In Northern Guangxi are crossed through North China is to the south, west to Shaanxi, Gansu, southwest to Sichuan, cloud The ground such as south, Guizhou, with mental-tranquilization, relax bowel, effect of hidroschesis, for deficiency of YIN-blood, dysphoria insomnia, and palpitation and severe palpitation, Dry constipation of intestines, night sweat due to yin deficiency.
Cornu cerve degelatinatum Chinese medicine name.It is animal in deer family sika deerCervus nippon Temminck or red deerCervus elaphusThe angle of Linnaeus etc. boils remaining bone slag after deer horn glue, with warming kidney and enhancing yang, the effect of astringing to arrest bleeding, commonly uses In the insufficiency of both the spleen and the kindey, leukorrhea, enuresis frequent micturition, metrostaxis, sore such as does not hold back at the treatment of illness.
The root of herbaceous peony（Scientific name：Paeonia lactiflora Pall.）Also referred to as spend Chinese herbaceous peony in vain, be Ranunculaceae Chinese herbaceous peony platymiscium, The existing long cultivation history of China, has won fame both at home and abroad, and it claims to spend Chinese herbaceous peony in vain, and its root can be used as medicine, perennial herb or undershrub, raw In hillside, the bushes in mountain valley or thick grass.
Chinese ephedra ephedra sinica, magnificent Chinese ephedra, Latin literary fame：Ephedra sinica Stapf, Ephedraceae, Ephedra draft are planted Thing is high 20-40 centimetres；Woody stems are short or into shape of crawling.There are three kinds of plants of Ephedra：Ephedra sinica (Ephedra sinica), Ephedra equisetina (Ephedra equisetina) and epheday intermedia (Ephedra intermedia), are draft shape shrub, using portion Position is herbaceous stem stem, is also important medicinal plant.Alkaloid enriches, and is the Main Resources for extracting ephedrine.Woody stems are few, Easy processing is refined；Due to being often born in Plain, hillside, riverbed, grassland etc., therefore it is easy to harvesting, because the sweating power of Chinese ephedra is strong, therefore Mild case, palpitaition, insomnia, the deficiency syndrome of the lung cough and asthma etc. of catching cold all should avoid use or use with caution.Old man, physically weak and children preferably use ephedra.
Thizoma curculiginis（Scientific name：Curculigo orchioides Gaertn.）, also known as ground palm fibre（Sichuan, Guizhou）, only thatch（Four River）, mountain Radix Codonopsis（Fujian）, whitestem serpentroot root（Yunnan）, Radix Glehniae（Hainan）, thatch claw, salsify, category Hypoxidaceae, florescence 4 ~ 9 Month.Medicinal plant, with tonifying the kidney and support yang, benefiting essence-blood, the effect of strengthening the bones and muscles and promoting circulation of blood detumescence.
Semen Cuscutae（Scientific name：Cuscuta chinensisLam.）, alias buddhist is true, beans parasitism, beans King of Hell, yellow silk, Huang silk Rattan, reticulate millettia, spun gold rattan etc..Annual parasitic draft.Stem winds, and yellow is very thin, without leaf.Inflorescence side is given birth to, few to spend or many flowers Generate small umbrella shape or small glomerule；Bract and squamella are small, flakey；Bennet is slightly sturdy；Calyx cup-shaped, connects below middle part Close, sliver triangular shape；Corolla white, kettle shape；Stamen the raw micro- lower place of corolla lobe sinus；Scale Long Circle；Ovary is subsphaeroidal, Style 2.Capsule is spherical, is almost all the corolla for harboring and is surrounded.Seed 2-49, it is filbert, it is avette, 1 millimeter is about, surface is thick It is rough.
Cassia twig alias：Liu Gui（Scientific name：Cinnamomum cassia Presl）It is canella Chinese cassia tree Cinnamomum The dry twig of cassia Presl.Spring, the harvesting of season in summer two, except defoliation, are dried, or section is dried, and this product is in elongated cylindrical, many Branch, 30~75cm, 0.3~1cm of butt diameter long.Surface rufous has vertical rib line, fine wrinkle and goose pimples shape to brown Leaf scar, branch trace, bud scar, hole skin point-like.Matter is hard and crisp, frangibility.2~4mm of slice thick, section skin zone rufous, woody part is yellowish-white Color to light yellowish brown, marrow is slightly square.There is special fragrance, taste is sweet, micro-pungent, skin zone's taste is denseer.
The membrane of a chicken's gizzard Chinese medicine name, is Phasianidae animal family chickenGallusgallusdomesticusBrisson's dries in ballast Wall.After killing chicken, chicken gizzard is taken out, inwall, cleaning, drying are peeled immediately.
Gingko also known as duck bottom sediment, mental eye, Buddhist refer to mandarin orange, and ginkgo, Gong Sunshuzi are the benevolences of ginkgo.Ellipse, long by 1.5~ 2.5cm, 1~2cm wide, thickness about 1cm.Surface yellow-white is fallow, and smooth, hard, one end is slightly sharp, and another end is blunt, and edge has 2 ~3 crest lines, mesosperm（Shell）Matter is hard, endotesta film quality.One end light brown, another end is golden yellow.Benevolence mealiness, centre tool is small Core, sweet, slight bitter.
Lopseed（Scientific name：Phryma leptostachya L. subsp. asiatica (Hara) Kitamura）Also known as medicine Anacamptis pyromaidalis, Staggergrass etc., perennial herb are high（10-）30-80 (-100）Centimetre, stem is upright, 4 prismatics, not branch or in top There are the branch with inflorescence, branch fork, green or lavender, spread all over down raw pubescence or have the pubescence of development in stem top, It is a small number of near without hair, leaf opposite；Blade ovate Long Circle, ovum shape lanceolar, ovate-elliptic are careless to ovate triangle or width egg shape Matter, spike life stem top and side shoot top, by micro- pubescence or pubescence；Corolla funnel-form tubular, it is long 6.5-7.5 millimeters, it is blue , to white, without hair, in cylinder portion abaxial side by pubescence, the narrow ellipse of achene is contained in bar-shaped place inner face for outside for purple, pale red Deposit in calyx, reflexed simultaneously presses close to rachis, seed 1, base life plants thin skin film quality, with pericarp symphysis, the month at florescence 6-10, fruiting period 8- December.
In the technical program, cloves, Chinese cassia tree, fructus alpiniae oxyphyllae and raspberry are important technical characteristic, for children's night In the technical field of the Chinese medicine composition of the enuresis, with novelty, creative and practicality, the term in the technical program is all Can be to be explained and understood with patent document in the art.
4th, specific embodiment
According to guidelines for examination, to it is used in the present invention such as " have ", "comprising" and " including " term should be understood to not Allot the presence or addition of one or more of the other element or its combination.
In the description of the invention, it is necessary to explanation, term " " center ", " on ", D score, "left", "right", " vertical ", The orientation or position relationship of the instruction such as " level ", " interior ", " outward " are the orientation or position relationship of general expression, are for only for ease of The description present invention is described with simplified, must have specific orientation, Yi Te rather than the device or element for indicating or imply meaning Fixed azimuth configuration and operation, therefore be not considered as limiting the invention.Additionally, term " first ", " second ", " the 3rd " It is only used for describing purpose, and it is not intended that indicating or implying relative importance.
In the description of the invention, it is necessary to illustrate, unless otherwise clearly defined and limited, term " installation ", " phase Company ", " connection " should be interpreted broadly, for example, it may be being fixedly connected, or being detachably connected, or be integrally connected；Can Being to mechanically connect, or electrically connect；Can be joined directly together, it is also possible to be indirectly connected to by intermediary, Ke Yishi Two connections of element internal.For the ordinary skill in the art, with concrete condition above-mentioned term can be understood at this Concrete meaning in invention.
As long as additionally, technical characteristic involved in invention described below different embodiments non-structure each other Can just be combined with each other into conflict.
In below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely retouched State, it is clear that described embodiment is only a part of embodiment of the invention, rather than whole embodiments.Based in the present invention Embodiment, the every other embodiment that those of ordinary skill in the art are obtained under the premise of creative work is not made, Belong to the scope of protection of the invention.
One embodiment of the invention, illustrates the present embodiment, is set to include Chinese medicine composition I and Chinese medicine group Compound II, according to ratio of weight and number,
Chinese medicine composition I is set to include 2 parts of 10 parts of cloves, 8 parts of Chinese cassia tree, 20 parts of fructus alpiniae oxyphyllae and raspberry,
Chinese medicine composition II be set to include 7 parts of intelligence development, 11 parts of grass-leaved sweetflag, 33 parts of the seed of Oriental arborvitae, 21 parts of cornu cerve degelatinatum, 4 parts of the root of herbaceous peony, 20 parts of 10 parts of Chinese ephedra, 11 parts of thizoma curculiginis, 6 parts of Semen Cuscutae, 7 parts of cassia twig, 40 parts of the membrane of a chicken's gizzard, 2 parts of gingko and lopseed.
Residue is removed after 2 parts of 10 parts of cloves, 8 parts of Chinese cassia tree, 20 parts of fructus alpiniae oxyphyllae and raspberry are crushed, is entered using rice vinegar Row mediation forms the Chinese medicine composition I of pasty state, and the Chinese medicine composition I of pasty state is attached on SHENQUE acupoint, at least one time daily, 7 parts of intelligence development, 20 parts of Chinese cassia tree, 11 parts of grass-leaved sweetflag, 33 parts of the seed of Oriental arborvitae, 21 parts of cornu cerve degelatinatum, 4 parts of the root of herbaceous peony, 10 parts of Chinese ephedra, 11 parts of thizoma curculiginis, 20 parts of 6 parts of Semen Cuscutae, 7 parts of cassia twig, 40 parts of the membrane of a chicken's gizzard, 2 parts of gingko and lopseed are put into 120ml water, are boiled 20- Taken after 30ml, it is sooner or later individual daily once continuously to attach and take 10 days for a course for the treatment of, must after attaching and the edible tri course for the treatment of Must disable 15 days.
Below in conjunction with clinical test and model case, the present invention is further described.
50 are randomly selected in Hospital Attached to Shandong Chinese Medical Univ., wherein man 30, female 20,3~12 years old age. The course of disease most short person's two weeks, most elder was up to 1 year, average half a year.
2nd, diagnostic criteria：
1st, sleep is relatively deep, is difficult to wake up, and wets the bed every night or every several days, and very then an enuresis nocturna bed is for several times；
2nd, age of onset is 5 more than one full year of life；
3rd, urine is conventional and urine cultivates discovery how without exception；
4th, x ray photograph inspection, part infant can find spina bifida occulta, visible its textural anomaly of urinary system x-ray radiography.
3rd, usage and dosage：During clinical practice, attach taken with one once a day, decocting takes juice about 20-30ml for twice, Half an hour warm is taken before meals twice to divide early, evening, attaches and take ten days for a course for the treatment of.
4th, criterion of therapeutical effect：1st, cure：The not enuresis again after controlling；
2nd, take a turn for the better：Enuresis number of times is reduced, and urination can be waken in sleep；
3rd, do not heal：The enuresis is unchanged.
5th, therapeutic effect：In the clinical observation case, the 2-5 course for the treatment of of taking medicine cures 42, takes a turn for the better 7, does not control for more 1 There is no toxic and side effect during treatment.
6th, model case：
Case 1：Lee, man, 7 years old.The middle enuresis is slept, urine volume is more, urine color is clear, sleep soundly, and is difficult to wake, pale white complexion, lassitude, The cold limb of shape is cold.After taking 3 courses for the treatment of of medicament prepared by Chinese medicine composition of the invention, the enuresis disappears, and can wake up urine, face at night Color is slightly ruddy；1 course for the treatment of is taken in consolidation, and all symptoms disappear, and cure.Follow-up is without recurrence.
Case 2：Certain is shut out, female 10 years old, sleeps the middle enuresis, frequent micturition and measures many, lusterless complexion, spiritlessness and weakness, lost the appetite, greatly Loose stool is thin.After taking 4 courses for the treatment of of medicament prepared by Chinese medicine composition of the invention, the enuresis disappears, and appetite increases；Consolidation takes 1 After the individual course for the treatment of, have rosy cheeks, each symptom disappears, cure.Follow-up is without recurrence.
Case 3：Bandit, man, 5 years old.Infant is wet the bed always from small, is diagnosed as infantile enuresis, is given Chinese medicine of the present invention and is controlled Treat, after attaching and taking 1 course for the treatment of, symptom is clearly better, after continuing to take 3 courses for the treatment of, symptom all disappears, recovery from illness, after 1 year Follow-up is without recurrence.
Second embodiment of the invention, illustrates the present embodiment, according to ratio of weight and number,
Chinese medicine composition I is set to include 3 parts of 16 parts of cloves, 12 parts of Chinese cassia tree, 23 parts of fructus alpiniae oxyphyllae and raspberry,
Chinese medicine composition II be set to include 9 parts of intelligence development, 13 parts of grass-leaved sweetflag, 36 parts of the seed of Oriental arborvitae, 25 parts of cornu cerve degelatinatum, 6 parts of the root of herbaceous peony, 24 parts of 14 parts of Chinese ephedra, 15 parts of thizoma curculiginis, 8 parts of Semen Cuscutae, 9 parts of cassia twig, 43 parts of the membrane of a chicken's gizzard, 6 parts of gingko and lopseed.
3rd embodiment of the invention, illustrates the present embodiment, according to ratio of weight and number,
Chinese medicine composition I is set to include 2 parts of 13 parts of cloves, 10 parts of Chinese cassia tree, 21 parts of fructus alpiniae oxyphyllae and raspberry,
Chinese medicine composition II be set to include 8 parts of intelligence development, 12 parts of grass-leaved sweetflag, 35 parts of the seed of Oriental arborvitae, 23 parts of cornu cerve degelatinatum, 5 parts of the root of herbaceous peony, 22 parts of 12 parts of Chinese ephedra, 13 parts of thizoma curculiginis, 7 parts of Semen Cuscutae, 8 parts of cassia twig, 41 parts of the membrane of a chicken's gizzard, 4 parts of gingko and lopseed.
4th embodiment of the invention, illustrates the present embodiment, according to ratio of weight and number,
Chinese medicine composition I is set to include cloves 10-16 parts, Chinese cassia tree 8-12 parts, fructus alpiniae oxyphyllae 20-23 parts and raspberry 2-3 parts,
Chinese medicine composition II is set to include intelligence development 7-9 parts, grass-leaved sweetflag 11-13 parts, seed of Oriental arborvitae 33-36 parts, cornu cerve degelatinatum 21-25 Part, root of herbaceous peony 4-6 parts, Chinese ephedra 10-14 parts, thizoma curculiginis 11-15 parts, Semen Cuscutae 6-8 parts, cassia twig 7-9 parts, the membrane of a chicken's gizzard 40-43 parts, gingko 2-6 parts and lopseed 20-24 parts.
Removed after cloves 10-16 parts, Chinese cassia tree 8-12 parts, fructus alpiniae oxyphyllae 20-23 parts and raspberry 2-3 parts is crushed residual Slag, using rice vinegar reconcile the Chinese medicine composition I to form pasty state, the Chinese medicine composition I of pasty state is attached on SHENQUE acupoint, often It at least one times, intelligence development 7-9 parts, Chinese cassia tree 20-24 parts, grass-leaved sweetflag 11-13 parts, seed of Oriental arborvitae 33-36 parts, cornu cerve degelatinatum 21-25 parts, Root of herbaceous peony 4-6 parts, Chinese ephedra 10-14 parts, thizoma curculiginis 11-15 parts, Semen Cuscutae 6-8 parts, cassia twig 7-9 parts, the membrane of a chicken's gizzard 40-43 parts, gingko 2-6 Part is put into 120ml water with lopseed 20-24 parts, is taken after being boiled 20-30ml, and the morning and evening is individual once daily, continuously pastes Echo and take 10 days for a course for the treatment of, attaching must disable 15 days with after the edible tri course for the treatment of.
5th embodiment of the invention, illustrates the present embodiment, according to ratio of weight and number,
Chinese medicine composition I is set to include 3 parts of 14 parts of cloves, 12 parts of Chinese cassia tree, 20 parts of fructus alpiniae oxyphyllae and raspberry,
Chinese medicine composition II be set to include 9 parts of intelligence development, 12 parts of grass-leaved sweetflag, 36 parts of the seed of Oriental arborvitae, 23 parts of cornu cerve degelatinatum, 4 parts of the root of herbaceous peony, 23 parts of 12 parts of Chinese ephedra, 13 parts of thizoma curculiginis, 8 parts of Semen Cuscutae, 8 parts of cassia twig, 42 parts of the membrane of a chicken's gizzard, 5 parts of gingko and lopseed.
By clinical test, result of the test shows the prescription of the 5th embodiment of the invention, to obesity and small The patient of youngster's enuresis nocturna, the effect of its treatment children's enuresis nocturna is best, while also there is the effect of improvement to obesity.
On the basis of with first of the invention, second, the 3rd, the 4th, the 5th embodiment, for patient Chinese medicine composition I is used alone also has therapeutic effect.
The present invention has lower feature：
1st, by the effective ingredient of cloves, Chinese cassia tree, fructus alpiniae oxyphyllae and raspberry SHENQUE acupoint permeate and intelligence development, grass-leaved sweetflag, the seed of Oriental arborvitae, The absorption of the pharmaceutical compositions of cornu cerve degelatinatum, the root of herbaceous peony, Chinese ephedra, thizoma curculiginis, Semen Cuscutae, cassia twig, the membrane of a chicken's gizzard, gingko and lopseed, realizes mending These drug regimens are caused that each efficacy of drugs produces synergy by kidney training unit and the treatment by Chinese herbs principle for replenishing qi to invigorate the spleen, so that Infantile enuresis can be effectively treated, therefore is improve the therapeutic effect to infantile enuresis and is not produced side effect.
2nd, due to because mostly asthenic symptoms, children's internal organs it is tender and lovely, shape gas does not fill, or is supported because the day after tomorrow loses, biochemical passive, or because of elder generation Its natural endowment is not good, and kidney fire void declines, can not warm invigorating the spleen sun, such speen-kidney dificiency, and then treating deficient cold, wing skin disturbance in functioning of QI, therefore See the enuresis, with tonifying kidney and to replenish qi to invigorate the spleen be the base therapy method that causes infantile enuresis, prescription of the invention is by god The absorption with Chinese medicinal ingredients is permeated in fault cave, meets base therapy method.
3rd, permeated and intelligence development, grass-leaved sweetflag, cypress in SHENQUE acupoint by the effective ingredient of cloves, Chinese cassia tree, fructus alpiniae oxyphyllae and raspberry The absorption of the pharmaceutical compositions of sub- benevolence, cornu cerve degelatinatum, the root of herbaceous peony, Chinese ephedra, thizoma curculiginis, Semen Cuscutae, cassia twig, the membrane of a chicken's gizzard, gingko and lopseed, Index during treatment to the hepatic and renal function of patient, blood, urine, excrement is tracked chemical examination, has not significant impact.
4th, due to devising technical characteristic of the invention, the effect of set in the independent of technical characteristic and each other, Shown by experiment, property indices of the invention are at least 1.7 times of existing property indices, are had by assessing There is good market value.
It is also other with cloves, Chinese cassia tree, fructus alpiniae oxyphyllae and raspberry it is same or like as middle medicine be all of the invention One of embodiment, and each technical characteristic of embodiment described above can be combined arbitrarily, to meet Patent Law, patent The requirement of detailed rules for the implementation and guidelines for examination, no longer to the implementation of all possible combination of each technical characteristic in above-described embodiment Example is all described.
Above-described embodiment is that one kind of the Chinese medicine composition for children's enuresis nocturna provided by the present invention realizes shape Formula, according to other deformations of scheme provided by the present invention, increases or reduces composition therein or step, or by the present invention For other technical fields close with the present invention, belong in protection scope of the present invention.

Claims (4)

1. a kind of Chinese medicine composition for children's enuresis nocturna, it is characterized in that：Include cloves, Chinese cassia tree, fructus alpiniae oxyphyllae and cover basin Son.
2. the Chinese medicine composition for children's enuresis nocturna according to claim 1, it is characterized in that：Include Chinese traditional medicine composition Thing I and Chinese medicine composition II,
Chinese medicine composition I is set to include cloves, Chinese cassia tree, fructus alpiniae oxyphyllae and raspberry,
Chinese medicine composition II be set to include intelligence development, grass-leaved sweetflag, the seed of Oriental arborvitae, cornu cerve degelatinatum, the root of herbaceous peony, Chinese ephedra, thizoma curculiginis, Semen Cuscutae, Cassia twig, the membrane of a chicken's gizzard, gingko and lopseed.
3. the Chinese medicine composition for children's enuresis nocturna according to claim 1, it is characterized in that：In being set to include Drug composition I and Chinese medicine composition II, according to ratio of weight and number,
Chinese medicine composition I is set to include cloves 10-16 parts, Chinese cassia tree 8-12 parts, fructus alpiniae oxyphyllae 20-23 parts and raspberry 2-3 parts,
Chinese medicine composition II is set to include intelligence development 7-9 parts, grass-leaved sweetflag 11-13 parts, seed of Oriental arborvitae 33-36 parts, cornu cerve degelatinatum 21-25 Part, root of herbaceous peony 4-6 parts, Chinese ephedra 10-14 parts, thizoma curculiginis 11-15 parts, Semen Cuscutae 6-8 parts, cassia twig 7-9 parts, the membrane of a chicken's gizzard 40-43 parts, gingko 2-6 parts and lopseed 20-24 parts.
4. the Chinese medicine composition for children's enuresis nocturna according to claim 1, it is characterized in that：In being set to include Drug composition I and Chinese medicine composition II, according to ratio of weight and number,
Chinese medicine composition I is set to include 3 parts of 14 parts of cloves, 12 parts of Chinese cassia tree, 20 parts of fructus alpiniae oxyphyllae and raspberry,
Chinese medicine composition II be set to include 9 parts of intelligence development, 12 parts of grass-leaved sweetflag, 36 parts of the seed of Oriental arborvitae, 23 parts of cornu cerve degelatinatum, 4 parts of the root of herbaceous peony, 23 parts of 12 parts of Chinese ephedra, 13 parts of thizoma curculiginis, 8 parts of Semen Cuscutae, 8 parts of cassia twig, 42 parts of the membrane of a chicken's gizzard, 5 parts of gingko and lopseed.
CN201611224750.2A 2016-12-27 2016-12-27 For the Chinese medicine composition of children's enuresis nocturna Pending CN106729281A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1593496A (en) * 2004-07-07 2005-03-16 武汉健民中药工程有限责任公司 Chinese medicine for treating enuresis in children and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1593496A (en) * 2004-07-07 2005-03-16 武汉健民中药工程有限责任公司 Chinese medicine for treating enuresis in children and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
吴力群等: "丁桂遗尿散敷脐结合推拿治疗小儿遗尿症临床观察", 《辽宁中医杂志》 *

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