CN106729097A - 一种治疗风温肺热的中药组合物 - Google Patents

一种治疗风温肺热的中药组合物 Download PDF

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CN106729097A
CN106729097A CN201710001006.4A CN201710001006A CN106729097A CN 106729097 A CN106729097 A CN 106729097A CN 201710001006 A CN201710001006 A CN 201710001006A CN 106729097 A CN106729097 A CN 106729097A
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张先军
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Abstract

本发明公开了一种治疗风温肺热的中药组合物。其中药原料及重量份配比为：生石膏40‑60份，麦冬20‑40份，元参20‑40份，淡豆豉10‑20份，水牛角5‑15份，石苇10‑20份，杏仁5‑15份，桑白皮10‑20份，芦根10‑20份，人参5‑15份，黄芩10‑20份，黄连5‑15份，地骨皮10‑20份，黄精10‑20份，知母5‑15份，独叶岩10‑20份，马勃5‑15份，罗汉果10‑20份，牡蛎10‑20份，石菖蒲10‑20份，竹叶20‑40份，半夏5‑15份，甘草5‑15份。本发明中药组合物具有养阴生津、清养补肺的功效，其配伍科学，疗效显著，作用可靠，无副作用。

Description

一种治疗风温肺热的中药组合物
技术领域
本发明属于中药技术领域，具体涉及一种治疗风温肺热的中药组合物。
背景技术
风温肺热病是由风热病邪犯肺，热壅肺气，肺失清肃所致，以发热，咳嗽，胸痛等为主要临床表现。冬春两季多发。从临床表现来看，风温肺热病可概括西医的急性肺炎、支气管周围炎和急性支气管炎等急性肺部感染疾病。目前，临床上治疗风温肺热病多采用点滴或注射抗生素治疗，但抗生素使用过多会使患者对抗生素的依赖性强，且副作用大。
发明内容
为了克服现有技术中采用抗生素治疗风温肺热存在药物依赖性强、副作用大的不足，本发明提供一种配伍科学、疗效显著、作用可靠、无副作用的治疗风温肺热的中药组合物。
本发明解决技术问题所采用的技术方案为：一种治疗风温肺热的中药组合物，其特征在于：其中药原料及重量份配比为：生石膏40-60份，麦冬20-40份，元参20-40份，淡豆豉10-20份，水牛角5-15份，石苇10-20份，杏仁5-15份，桑白皮10-20份，芦根10-20份，人参5-15份，黄芩10-20份，黄连5-15份，地骨皮10-20份，黄精10-20份，知母5-15份，独叶岩10-20份，马勃5-15份，罗汉果10-20份，牡蛎10-20份，石菖蒲10-20份，竹叶20-40份，半夏5-15份，甘草5-15份。
本发明的优选技术方案是：一种治疗风温肺热的中药组合物，其特征在于：其中药原料及重量份配比为：生石膏50份，麦冬30份，元参30份，淡豆豉15份，水牛角10份，石苇15份，杏仁10份，桑白皮15份，芦根15份，人参10份，黄芩15份，黄连10份，地骨皮15份，黄精15份，知母10份，独叶岩15份，马勃10份，罗汉果15份，牡蛎15份，石菖蒲15份，竹叶30份，半夏10份，甘草10份。
风温肺热由于邪热内盛于肺，肺失宣降所表现的肺实热证侯。热邪犯肺，肺失清肃，气逆于上，故咳嗽气喘，肺热上熏咽喉，气血壅滞，故咽喉红肿疼痛，里热蒸腾则发热，热盛伤津则口渴。因此治疗风温肺热应以清热解毒，养阴生津，清养补肺为治则。本发明的中药组合物中，竹叶清热解毒，利水消肿，生石膏清热泻火，除烦止渴，二药相须，清透气分余热，除烦止渴，共为君药。麦冬滋阴降火，元参养阴生津，黄精滋肾润肺，养阴生津，三药相使，滋阴润肺；人参大补元气，与上三种滋阴药相使，补气养阴生津为臣药。佐以淡豆豉宣发郁热，水牛角清热解毒，凉血，石苇清肺泄热，桑白皮清肺泄热，知母清热泄火，四药相使清泄肺热；芦根清热生津，黄精滋肾润肺，养阴生津，独叶岩珠滋阴清热，地骨皮滋阴清肺，四药相使，生津润肺，肺热蒸腾，津液可以肃降肺热；黄芩清热燥湿，黄连清热燥湿，罗汉果清热润肺，马勃清肺利咽，四药相使，润肺利咽；杏仁祛痰止咳，下气开痹，石菖蒲化湿行气，二者一升一降，宣肺同时行气；牡蛎收敛固涩，半夏和胃止呕降逆。最后用甘草调和诸药，为使药。纵观全方，清热与益气养阴并用，祛邪扶正兼顾，清而不寒，补而不滞，使热清烦除，气津得复，诸症自愈。
本发明所提供的中药组合物配伍科学，本发明的中药组合物按常规的水煎法制取药剂服用。经临床应用验证，其疗效显著，作用可靠，药性平和，未出现毒副作用，总有效率96%，治愈率达76%。
具体实施方式
下面结合实施例对本发明做进一步说明。
实施例1
一种治疗风温肺热的中药组合物，其中药原料及重量配比为：生石膏50g，麦冬30g，元参30g，淡豆豉15g，水牛角10g，石苇15g，杏仁10g，桑白皮15g，芦根15g，人参10g，黄芩15g，黄连10g，地骨皮15g，黄精15g，知母10g，独叶岩15g，马勃10g，罗汉果15g，牡蛎15g，石菖蒲15g，竹叶30g，半夏10g，甘草10g。
实施例2
一种治疗风温肺热的中药组合物，其中药原料及重量配比为：生石膏40g，麦冬40g，元参20g，淡豆豉20g，水牛角5g，石苇20g，杏仁5g，桑白皮20g，芦根10g，人参15g，黄芩10g，黄连15g，地骨皮10g，黄精20g，知母5g，独叶岩20g，马勃5g，罗汉果20g，牡蛎10g，石菖蒲20g，竹叶20g，半夏15g，甘草5g。
实施例3
一种治疗风温肺热的中药组合物，其中药原料及重量配比为：生石膏60g，麦冬20g，元参40g，淡豆豉10g，水牛角15g，石苇10g，杏仁15g，桑白皮10g，芦根20g，人参5g，黄芩20g，黄连5g，地骨皮20g，黄精10g，知母15g，独叶岩10g，马勃15g，罗汉果10g，牡蛎20g，石菖蒲10g，竹叶40g，半夏5g，甘草15g。
实施例4
一种治疗风温肺热的中药组合物，其中药原料及重量配比为：生石膏45g，麦冬35g，元参25g，淡豆豉18g，水牛角8g，石苇18g，杏仁8g，桑白皮18g，芦根12g，人参13g，黄芩12g，黄连13g，地骨皮12g，黄精18g，知母8g，独叶岩18g，马勃8g，罗汉果18g，牡蛎12g，石菖蒲18g，竹叶25g，半夏13g，甘草8g。
实施例5
一种治疗风温肺热的中药组合物，其中药原料及重量配比为：生石膏55g，麦冬25g，元参35g，淡豆豉12g，水牛角13g，石苇12g，杏仁13g，桑白皮12g，芦根18g，人参8g，黄芩18g，黄连8g，地骨皮18g，黄精12g，知母13g，独叶岩12g，马勃13g，罗汉果12g，牡蛎18g，石菖蒲12g，竹叶35g，半夏8g，甘草13g。
下面结合本发明的中药组合物，进行临床疗效实验如下：
1、临床病例选择：挑选50例风温肺热患者，年龄20-65岁。
2、临床症状：
a）、以身热、咳嗽、烦渴，或伴气急、胸痛为主症；
b）、病重者可见壮热，颜面潮红，烦躁不安，神昏谵语，或四肢厥冷等症；
c）、冬春两季较多。具有起病急、传变快、病程短的特点；
d）、血白细胞总数及中性粒细胞升高者，属细菌性感染；正常或偏低者以病毒性感染为主；
e）、肺部有实变体征，或可闻及干湿性罗音；
f）、痰直接涂片或培养可以找到病原体；
g）、胸部X线透视或摄片，可见一侧或两侧肺叶或肺段炎性阴影。
3、实验方法：将上述患者随机分为实验治疗组及对照治疗组两组，每组25人，其中，实验治疗组采用本发明实施例一提供的中药组合物，其是将本发明提供的中药原料按照传统水煎法煎煮两遍取汁约400ml，分早、晚两次温热服用，一天一剂，七天一疗程。对照治疗组采用：青霉素类、第一代头孢菌素等点滴治疗。
4、疗效标准：
1）、治愈：症状及体征消失，实验室及X线等检查恢复正常；
2）、好转：症状及体征、实验室检查等有所改善，x线检查肺部病灶尚未完全吸收；
3）、未愈：病情未见好转。
5、实验结果：
实验治疗组：治疗3-6个疗程，治愈19例，有效5例，无效1例。经不良反应（ADR）安全性评价，治疗期间未发生毒副作用。
对照治疗组：治疗一周，风温肺热症状治愈12例，治疗二周后，累计风温肺热治愈19例，治疗四周后，累计风温肺热治愈23例，但治疗2-3个月后有3例患者病情出现反复。
通过上述统计比较可以看出，采有西药的对照治疗组治疗风温肺热治疗速度，但药物依赖性强，停药后易反复。本发明提供的实验治疗组的治疗速度慢，但治疗彻底，病情不反复。
6、典型病例：
病例一：肖某，女，21岁。患者自述中暑感冒后一个月，持续感觉身热无汗，恶风寒，偶有轻微咳嗽，痰少，头微痛，口微渴。舌边尖红，苔薄白，脉浮数。服用本发明的中药组合物制备的药剂2个疗程后，治愈。随访半年，未复发。
病例二：刘某，男，62岁。患者自述半月前某日半夜起来，自觉身热口渴，烦躁不安，轻微咳嗽，咽痛，后来咳嗽日渐加重，呼吸胸腔有痛感，痰中带少许血丝。舌红苔黄，脉滑数。服用本发明的中药组合物制备的药剂1个疗程，各症状明显好转，痰量减少，无血丝；续服2个疗程后，症状消失，治愈。随访半年，未复发。
中药原料用量也是治疗效果的关键因素，其用量必须恰当。本发明用于临床实验的各中药原料用量是本发明的最佳用量，其适用范围广。其中，生石膏50g，用量大，竹叶20g，用量大，二药相须，清透气分余热，除烦止渴，石膏清热泻火，大量应用效果才佳。麦冬30g，元参30g，用量大，滋阴降火，养阴生津，肺内蒸腾，气津两伤，因此要大量应用滋阴之药以养阴生津，同时，用人参10g，与二药相使，补气养阴，生津润肺。芦根15g清热生津，黄精15g滋肾润肺，养阴生津，独叶岩珠15g滋阴清热，地骨皮15g滋阴清肺，四种滋阴生津药量都大，助臣药之功效。

Claims (2)

1.一种治疗风温肺热的中药组合物，其特征在于：其中药原料及重量份配比为：生石膏40-60份，麦冬20-40份，元参20-40份，淡豆豉10-20份，水牛角5-15份，石苇10-20份，杏仁5-15份，桑白皮10-20份，芦根10-20份，人参5-15份，黄芩10-20份，黄连5-15份，地骨皮10-20份，黄精10-20份，知母5-15份，独叶岩10-20份，马勃5-15份，罗汉果10-20份，牡蛎10-20份，石菖蒲10-20份，竹叶20-40份，半夏5-15份，甘草5-15份。
2.根据权利要求1所述的一种治疗风温肺热的中药组合物，其特征在于：其中药原料及重量份配比为：生石膏50份，麦冬30份，元参30份，淡豆豉15份，水牛角10份，石苇15份，杏仁10份，桑白皮15份，芦根15份，人参10份，黄芩15份，黄连10份，地骨皮15份，黄精15份，知母10份，独叶岩15份，马勃10份，罗汉果15份，牡蛎15份，石菖蒲15份，竹叶30份，半夏10份，甘草10份。
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