CN106729041A - It is a kind of to treat Chinese medicine preparation of myocardial infarction and preparation method thereof - Google Patents

It is a kind of to treat Chinese medicine preparation of myocardial infarction and preparation method thereof Download PDF

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CN106729041A
CN106729041A CN201611166996.9A CN201611166996A CN106729041A CN 106729041 A CN106729041 A CN 106729041A CN 201611166996 A CN201611166996 A CN 201611166996A CN 106729041 A CN106729041 A CN 106729041A
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chinese medicine
preparation
myocardial infarction
treatment
course
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郭兆滨
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A61K36/575—Magnolia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/66—Papaveraceae (Poppy family), e.g. bloodroot
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/69—Polygalaceae (Milkwort family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725—Ziziphus, e.g. jujube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734—Crataegus (hawthorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
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  • Alternative & Traditional Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

By weight it is to include following traditional Chinese medicine ingredients the invention discloses a kind of Chinese medicine preparation for treating myocardial infarction：Poria cocos 13g, radix pseudostellariae 13g, calamus 8g, polygala 8g, red sage root 13g, Ligusticum wallichii 13g, corydalis tuber 8g, cassia twig 6g, wheat 13g, bark of official magnolia 13g, dried immature fruit of citron orange 13g, charred FRUCTUS CRATAEGI 13g, santal 5g, honey-fried licorice root 3g, 5 pieces of date.The preparation and application of Chinese medicine composition of the present invention：It is decocted in water for oral dose：Daily 1 dose, 7 doses be a course for the treatment of, it is necessary to the course for the treatment of of medication 26.

Description

It is a kind of to treat Chinese medicine preparation of myocardial infarction and preparation method thereof
Technical field
It is to be related to a kind of Chinese medicine preparation for treating myocardial infarction specifically the invention belongs to Chinese medicine composition.
Background technology
Myocardial infarction is mainly expanded by heart circle, and heart rate is fast, and apex decreased loudness of first sound may occur in which fourth heart sound galloping horse Rule, had pericardiac friction sound at 2~3 days more.Apical region of heart may occur in which coarse systolic murmur or barlow syndrome, be two Caused by cusp dysfunction of papillary muscle or fracture, there can be various arrhythmia cordis.Blood pressure reduction.Can have with arrhythmia cordis, shock or Other related signs of heart failure.The patient clinical that myocardial infarction occurs often has violent pectoralgia, and the duration is long, rests or buccal nitre Acid glycerol piece can not be allowed to alleviate, with fear, dying sense, sensation of asphyxia and sweat all over, the performance such as have the fidgets, can have not Gram, arrhythmia cordis and heart failure even die suddenly.Symptom being treated Western medicine, it is impossible to effectively treat the disease, and controlled using Chinese herbal medicine more Treat, with safe and effective advantage.
The present invention for treating the Chinese medicine preparation of myocardial infarction nursing, for myocardial infarction etiology and pathogenesis, with clearing heat and detoxicating, Clearing heat and promoting diuresis, cleaning heat and expelling wind, restore menstrual flow and invigorate blood circulation, promoting circulation of blood detumescence, promoting blood circulation to remove blood stasis, dissipating bind dredging collateral be the rules for the treatment of, reach cold dispelling Wen Yang, promote blood circulation Analgesic, treats effect of myocardial infarction.
The content of the invention
Present invention aim to address the problem in prior art, spy provide a kind of effect substantially, the course for the treatment of is shorter controls Treat the Chinese medicine preparation of myocardial infarction.
In order to realize foregoing invention purpose, the present invention is made the raw material composition and its weight proportion of the effective ingredient For：Poria cocos 13g, radix pseudostellariae 13g, calamus 8g, polygala 8g, red sage root 13g, Ligusticum wallichii 13g, corydalis tuber 8g, cassia twig 6g, wheat 13g are thick Plain 13g, dried immature fruit of citron orange 13g, charred FRUCTUS CRATAEGI 13g, santal 5g, honey-fried licorice root 3g, 5 pieces of date.The preparation of Chinese medicine composition of the present invention and use Method：It is decocted in water for oral dose：Daily 1 dose, 7 doses be a course for the treatment of, it is necessary to the medication 2-6 courses for the treatment of.
The present invention selects natural drug for treating the Chinese medicine preparation of myocardial infarction, for myocardial infarction etiology and pathogenesis, respectively Taste medicinal material respectively has its effect, coordinates mutually, radix pseudostellariae bushing QI invigorating in side；The logical heart of calamus is had one's ideas straightened out；Poria cocos, polygala can clear away heart-fire middle void Heat；The red sage root, Ligusticum wallichii is promoting blood circulation and removing blood stasis；Cassia twig, Radix Glycyrrhizae coordinating the drug actions of a prescription, corydalis tuber, santal analgesic qi-regulating；The bark of official magnolia, the dried immature fruit of citron orange, charred FRUCTUS CRATAEGI reason Gas；Gan Mai, date are with slow liver urgency calming heart will.Above-mentioned all herbal medicines are shared, and mutually collaboration brings out the best in each other, and plays clearing heat and detoxicating, clear altogether Hot dampness removing, cleaning heat and expelling wind, restore menstrual flow and invigorate blood circulation, promoting circulation of blood detumescence, promoting blood circulation to remove blood stasis, the effect of dissipating bind dredging collateral, reach cold dispelling Wen Yang, promote blood circulation only Bitterly, effect of myocardial infarction is treated.
Specific embodiment
Embodiment 1：A kind of Chinese medicine preparation for treating myocardial infarction, by weight including following traditional Chinese medicine ingredients：Poria cocos 13g, radix pseudostellariae 13g, calamus 8g, polygala 8g, red sage root 13g, Ligusticum wallichii 13g, corydalis tuber 8g, cassia twig 6g, wheat 13g, bark of official magnolia 13g, Dried immature fruit of citron orange 13g, charred FRUCTUS CRATAEGI 13g, santal 5g, honey-fried licorice root 3g, 5 pieces of date.
It is decocted in water for oral dose：Daily 1 dose, 7 doses be a course for the treatment of, it is necessary to the medication 2-6 courses for the treatment of.
The clinical treatment effect of the Chinese medicine preparation for myocardial infarction nursing of the present invention is illustrated below by way of practical example Really.
1st, clinical data
50 myocardial infarction patients, patient's average age 45 ± 20 years old (25~65 years old), meet "《Chinese medical disease diagnoses curative effect mark It is accurate》Myocardial infarction diagnosis standard in (State Administration of Traditional Chinese Medicine's promulgation) ", full diagnostics is myocardial infarction patient.
50 myocardial infarction patients all have the symptoms such as pectoralgia, cardiac arrhythmia, heart failure.
Criterion of therapeutical effect
Cure：Clinical symptom disappearance, cardiac muscle detection recovers normal；
It is effective：Clinical symptoms substantially mitigate, and patient's rhythm of the heart is neat, painless；
It is invalid：Clinical symptoms are without substantially mitigation, exacerbation of symptoms, and it is invalid to be judged to.
3rd, treatment results
After 50 myocardial infarction patients treat 3~4 courses for the treatment of, cure 38, treat effective 8, invalid 2.Treatment total effective rate It is 93%.
Typical case：
In certain man, 60 years old, occurred pectoralgia suddenly without obvious inducement before five hours, degree is violent, it is impossible to alleviate, companion sweats all over, It is weak, carry out institute's emergency treatment.Previously there is penicillin anaphylaxis.Deny surgery trauma history.Deny history of transfusing blood.Deny tuberculosis, hepatitis, typhoid fever etc. Infectious disease.Deny hypertension, hyperlipemia, diabetes medical history.There are GERD, atrophic gastritis medical history.Immunization campaign Patient can not recall.Class origin ancestral home, occupies Shanghai long.Deny epidemic disease water epidemic disease ground contact history, there is a smoking history many decades, 200 1 year, it is no Recognize history of drinking history.Family is healthy per capita, denies familial inheritance disease.Physical examination：T：36.8 DEG C, P：74 beats/min, R：45 beats/min, BP： 90/60mmHg.Mind is clear, build is partially fat, and without anaemia looks, skin sclera is without xanthochromia blutpunkte.Superficial lymph knot is not and enlargement.Pharynx Without hyperemia, tonsillotome is little.Neck is soft, and horizontal position jugular vein is full obvious, and tracheae is placed in the middle, and thyroid gland is little.Thorax is double without deformity Pulmonary respiration sound is low.Do not hear and dry and wet rale.Heart circle less, has no that praising sample beats, and 74 beats/min of heart rate, rule is neat, and each valve area is not And obvious noise.Abdomen is grand soft, without tenderness, is not touched under liver spleen rib, and hepatic region button is bitterly（-）, murphy ' s levy（-）, shifting dullness (-), double lower limb has no edema.Laboratory examination and other inspections：CK：190U/L, AST：30U/L, LDH：300U/L, WBC： 11×109/L.Electrocardiogram：IIth, III, the avF ST-Segments back of a bow is raised upwards, v2-6 Precordial ST segment depressions, V3R, V4R, V5RST sections is raised.After determine treatment by Chinese herbs, take 6 doses of inventive formulation, be decocted in water for oral dose, daily 1 dose, it is daily 3 clothes.Second examines：Pain Pain slightly sense mitigates, 12 doses of following the service, and three examine：Pain elementary solution is removed, and is after treatment effect afterwards, is advised and is continued to take 12 doses.Follow-up 1 year, all go well.

Claims (2)

1. a kind of Chinese medicine preparation for treating myocardial infarction, it is characterised in that：The Chinese medicine preparation includes following Chinese medicine by weight Composition：Poria cocos 13g, radix pseudostellariae 13g, calamus 8g, polygala 8g, red sage root 13g, Ligusticum wallichii 13g, corydalis tuber 8g, cassia twig 6g, wheat 13g, Bark of official magnolia 13g, dried immature fruit of citron orange 13g, charred FRUCTUS CRATAEGI 13g, santal 5g, honey-fried licorice root 3g, 5 pieces of date.
2. the preparation and application of Chinese medicine composition of the present invention：It is decocted in water for oral dose：Daily 1 dose, 7 doses be a course for the treatment of, it is necessary to medication 2-6 The course for the treatment of.
CN201611166996.9A 2016-12-16 2016-12-16 It is a kind of to treat Chinese medicine preparation of myocardial infarction and preparation method thereof Withdrawn CN106729041A (en)

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CN201611166996.9A CN106729041A (en) 2016-12-16 2016-12-16 It is a kind of to treat Chinese medicine preparation of myocardial infarction and preparation method thereof

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CN201611166996.9A CN106729041A (en) 2016-12-16 2016-12-16 It is a kind of to treat Chinese medicine preparation of myocardial infarction and preparation method thereof

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