CN106728043A - It is a kind of to contribute to pharmaceutical composition of union and preparation method thereof - Google Patents
It is a kind of to contribute to pharmaceutical composition of union and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/34—Copper; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
- A61K36/12—Filicopsida or Pteridopsida
- A61K36/126—Drynaria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/237—Notopterygium
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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Abstract
The invention belongs to pharmaceutical technology field, and in particular to a kind of to contribute to pharmaceutical composition of union and preparation method thereof.A kind of pharmaceutical composition for contributing to union, it includes following component, is weight portion：Pseudo-ginseng：20 45 parts, the bark of eucommia：18 40 parts, the root of herbaceous peony：20 40 parts, the rhizome of davallia：5 10 parts, Radix Angelicae Sinensis：15 32 parts, safflower：8 16 parts, wild lettuce：8 15 parts, smallflower beggarticks herb：10 20 parts, 8 15 parts of edible debregeasia root and leaf, 10 20 parts of black ancient tile, native copper：5 10 parts, notopterygium root：2 10 parts, Red Coppe：39 parts, pierce brain bag：28 parts.
Description
Technical field
The invention belongs to pharmaceutical technology field, and in particular to a kind of pharmaceutical composition for contributing to union and its preparation
Method.
Background technology
Fracture is that the continuity of bone structure is broken wholly or in part.Be more common in children and the elderly, young people also when
There is generation.Patient is often-individual position fracture, and minority is multiple fracture.Through appropriate treatment in time, most patients can recover former
The function of coming, a few patients can leave different degrees of sequelae.
The therapeutic modality of fracture typically uses three step rescue by stages, the limitation of the traditional remedies thoroughly broken, additionally, wound
Mouth severe pain, there is dyskinesia in local swelling, extravasated blood after wound.Patient is moved less as far as possible after there is wound.The treatment side of fracture
Method is described below：Firstth, reset：It is that the fracture site that will be shifted over after fracture recovers normal or close to original normal position again
Put, acted on the support for recovering bone again.This is the treatment method of conventional fracture.Secondth, it is fixed：After the reduction of the fracture, because
For its is unstable, it is susceptible to shift again, therefore is fixed on satisfied position using different methods, makes it gradually
Healing.If by surgical incision upper steel plate, draw point, intramedullary needle, screw etc., just crying interior fixation.The treatment of conventional fracture
Method has：Plintlet, plaster bandage, exterior fixing rack, traction braking fixation etc., these cry outer fixation.3rd, functional training：
The treatment method of this fracture is to increase the blood circulation of fracture surrounding tissue by injured limb contraction of muscle, promotes fracture
Healing, prevents muscular atrophy, by actively or passively movable loose joint, prevents synarthrophysis, capsular ligament contracture etc..
The method of above-mentioned treatment fracture, for patient, the course for the treatment of is long, and medical expense is big.Existing traditional Chinese medical therapeutic program
Method using resetting, traditional Chinese medicine for oral administration adds external application medical ointment, not only the course for the treatment of is slow for this treatment method, and effect is poor, is unfavorable for disease
The recovery of people.Contain noxious material lead in external application medical ointment, lead is a kind of to the great toxic heavy metal of harm, lead and its change
Compound will cause harm into after body to the multiple systems such as nerve, hematopoiesis, digestion, kidney, angiocarpy and endocrine, if content
It is too high, lead poisoning can be caused.This external application medical ointment can cause secondary injury to patient.
The content of the invention
Part in view of the shortcomings of the prior art, the present invention proposes a kind of drug regimen for contributing to union
Thing, the pharmaceutical composition for bone fracture therapeutic effect substantially, can accelerate the growth of poroma, when shortening the healing of fracture
Between.And lead is not contained in the pharmaceutical composition, secondary injury is not resulted in patient.
The present invention is adopted the following technical scheme that：
A kind of pharmaceutical composition for contributing to union, it includes following component, is weight portion：Pseudo-ginseng：20-45
Part, the bark of eucommia：18-40 parts, the root of herbaceous peony：20-40 parts, the rhizome of davallia：5-10 parts, Radix Angelicae Sinensis：15-32 parts, safflower：8-16 parts, wild lettuce：8-
15 parts, smallflower beggarticks herb：10-20 parts, edible debregeasia root and leaf 8-15 parts, black ancient tile 10-20 parts, native copper：5-10 parts, notopterygium root：2-10 parts, red copper
Bits：3-9 parts, pierce brain bag：2-8 parts.
Further, also including dried immature fruit of citron orange 12-18 parts.
Further, including following component, it is weight portion：Pseudo-ginseng：20 parts, the bark of eucommia：18 parts, the root of herbaceous peony：20 parts, bone is broken
Mend：10 parts, Radix Angelicae Sinensis：15 parts, safflower：8 parts, wild lettuce：15 parts, smallflower beggarticks herb：10 parts, 15 parts of edible debregeasia root and leaf, 10 parts of black ancient tile is natural
Copper：5 parts, notopterygium root：10 parts, Red Coppe：3 parts, pierce brain bag：2 parts.
Further, including following component, it is weight portion：Pseudo-ginseng：30 parts, the bark of eucommia：25 parts, the root of herbaceous peony：30 parts, bone is broken
Mend：8 parts, Radix Angelicae Sinensis：22 parts, safflower：10 parts, wild lettuce：11 parts, smallflower beggarticks herb：15 parts, 12 parts of edible debregeasia root and leaf, 18 parts of black ancient tile is natural
Copper：8 parts, notopterygium root：7 parts, Red Coppe：6 parts, pierce brain bag：5 parts.
Further, pseudo-ginseng is at least one in chrysanthemum pseudo-ginseng or Bulbilus boussingaultiae pseudobaselloidis.
A kind of preparation method of the pharmaceutical composition for contributing to union, it is comprised the following steps：
S1, takes claim 1-5 any one described pharmaceutical compositions, is soaked 2~4 hours with 3 times of boiling water of volume；
S2, add 5 times of volumes decocting boil 1-2 hours after filter；
The dregs of a decoction that step S2 is obtained are added 10 times of water of volume by S3, are filtered after decocting 0.5-1 hours；
S4, is condensed into medicinal extract, according to conventional preparation method by the filtrate merging of step S2 and step S3, centrifugation, filtrate
It is processed, is made pharmaceutical preparation.
Further, pharmaceutical preparation is external preparation or oral formulations.
Further, it is first to use to be boiled by fire to be decocted described in step S2 or/and step S3, then slow using slow fire
Decoct.
Further, it is filtered into described in step S2 or/and step S3 and is filtered while hot.
Further, the water temperature in step S1 is 95 DEG C -100 DEG C.
Beneficial effects of the present invention are：Function of the present invention with blood circulation promoting and enriching, for mending eliminating stasis to subdue swelling, can dissipate
Phlegm, promoting blood circulation, promote bone growth, and fibrin can be promoted to generate, and the present invention has significant curative effect and nontoxic pair to fracture
Effect.Preparation method step of the present invention is simple simultaneously, and low production cost is easy to industrialized production and application.
Specific embodiment
The present invention is further explained with reference to specific embodiment, but specific embodiment is not to the present invention
It is limited in any way.Unless stated otherwise, reagent involved in embodiment, method are reagent and method commonly used in the art.
The present invention proposes a kind of pharmaceutical composition for contributing to union, and it includes following component, is weight portion：
Pseudo-ginseng：20-45 parts, the bark of eucommia：18-40 parts, the root of herbaceous peony：20-40 parts, the rhizome of davallia：5-10 parts, Radix Angelicae Sinensis：15-32 parts, safflower：8-16
Part, wild lettuce：8-15 parts, smallflower beggarticks herb：10-20 parts, edible debregeasia root and leaf 8-15 parts, black ancient tile 10-20 parts, native copper：5-10 parts, Qiang
It is living：2-10 parts, Red Coppe：3-9 parts, pierce brain bag：2-8 parts.
Embodiment one：A kind of pharmaceutical composition for contributing to union
Pseudo-ginseng：20 parts, the bark of eucommia：18 parts, the root of herbaceous peony：20 parts, the rhizome of davallia：10 parts, Radix Angelicae Sinensis：15 parts, safflower：8 parts, wild lettuce：
15 parts, smallflower beggarticks herb：10 parts, 15 parts of edible debregeasia root and leaf, 10 parts of black ancient tile, native copper：5 parts, notopterygium root：10 parts, Red Coppe：3 parts, pierce brain
Bag：2 parts, 12 parts of the dried immature fruit of citron orange.
The preparation method of the pharmaceutical composition：It is comprised the following steps：
S1, pharmaceutical composition is soaked 2 hours with 3 times of the 95 of volume DEG C of boiling water；
S2, add 5 times of volumes decocting boil 2 hours after filter；
The dregs of a decoction that step S2 is obtained are added 10 times of water of volume by S3, are filtered after decocting 0.5 hour；
S4, is condensed into medicinal extract, according to conventional preparation method by the filtrate merging of step S2 and step S3, centrifugation, filtrate
It is processed, is made oral formulations.
Embodiment two：A kind of pharmaceutical composition for contributing to union
Pseudo-ginseng：30 parts, the bark of eucommia：25 parts, the root of herbaceous peony：30 parts, the rhizome of davallia：8 parts, Radix Angelicae Sinensis：22 parts, safflower：10 parts, wild lettuce：
11 parts, smallflower beggarticks herb：15 parts, 12 parts of edible debregeasia root and leaf, 18 parts of black ancient tile, native copper：8 parts, notopterygium root：7 parts, Red Coppe：6 parts, pierce brain bag：
5 parts.
The preparation method of the pharmaceutical composition：It is comprised the following steps：
S1, pharmaceutical composition is soaked 3 hours with 3 times of boiling water of volume；
S2, adds 5 times of water of volume first using being boiled by fire, and is filtered after then being decocted 1.5 hours slowly using slow fire；
The dregs of a decoction that step S2 is obtained are added 10 times of water of volume by S3, then slow using slow fire first using being boiled by fire
Filtered after decocting 1 hour；
S4, is condensed into medicinal extract, according to conventional preparation method by the filtrate merging of step S2 and step S3, centrifugation, filtrate
It is processed, is made oral formulations.
It should be noted that pseudo-ginseng is at least one in chrysanthemum pseudo-ginseng or Bulbilus boussingaultiae pseudobaselloidis.The medicine of embodiment one and embodiment two
Compositions not only can be made into oral formulations, may also be fabricated which external preparation.In order to ensure the property of medicine of pharmaceutical composition, in embodiment
One and embodiment two in step S2 or/and step S3 described in be filtered into and filter while hot.
Standards of Chinese Medical Syndrome Differentiation
According to《Chinese medical disease Standardization of diagnosis and curative effect》(State Administration of Traditional Chinese Medicine [S] Nanjing：Publishing house of Nanjing University,
1994:94) formulate：There is pain in all traumatic injuries, and swelling, bony crepitus, abnormal movement, limb activity is limited, the dermal ecchymosis,
Dimly red tongue has trace spot, and tongue is white, wiry and frequent pulse, belongs to syndrome of qi stagnation and blood stasis person.And made a definite diagnosis by x-ray inspection.Exclude pathologic
Fracture.
Physical data, chooses 50 fracture of rib patients, wherein man 25, female 25.Average 30 years old, it is simple rib
Fracture, course of disease 1-5d.It is divided into 2 groups, every group 25.
The oral formulations prepared in three groups of oral embodiments one and two of difference, 3 times a day.It is within 30 days a course for the treatment of.
Criterion：With reference to People's Republic of China's traditional Chinese medical science professional standard《Disease of tcm Standardization of diagnosis and curative effect》.Cure：Bone
Folding contraposition satisfaction has been healed, and partial gall has disappeared, and coughs and deep breathing without pain；Take a turn for the better：Fracture reduction is good, basic healing,
Part has mild pain and tenderness, thorax extruding (scholar)；Do not heal：Fracture does not heal, and partial gall is not improved, thorax extruding
Levy the positive.
For the oral formulations of embodiment one, wherein 15 healings, 10 improvements；Oral system in for embodiment two
Agent, wherein 18 healings, 7 improvements.
After healing weekly to all follow-up of patients once, do not found in one month patient disease relapse and substantially
Adverse reaction.
Although specifically showing and describing the present invention with reference to preferred embodiment, those skilled in the art should be bright
In vain, do not departing from the spirit and scope of the present invention that appended claims are limited, in the form and details can be right
The present invention makes a variety of changes, and is protection scope of the present invention.
Claims (10)
1. a kind of pharmaceutical composition for contributing to union, it is characterised in that：It includes following component, is weight portion：Three
Seven：20-45 parts, the bark of eucommia：18-40 parts, the root of herbaceous peony：20-40 parts, the rhizome of davallia：5-10 parts, Radix Angelicae Sinensis：15-32 parts, safflower：8-16 parts,
Wild lettuce：8-15 parts, smallflower beggarticks herb：10-20 parts, edible debregeasia root and leaf 8-15 parts, black ancient tile 10-20 parts, native copper：5-10 parts, notopterygium root：2-
10 parts, Red Coppe：3-9 parts, pierce brain bag：2-8 parts.
2. the pharmaceutical composition of union is contributed to as claimed in claim 1, it is characterised in that：Also include dried immature fruit of citron orange 12-18 parts.
3. the pharmaceutical composition of union is contributed to as claimed in claim 1, it is characterised in that：Including following component, it is
Weight portion：Pseudo-ginseng：20 parts, the bark of eucommia：18 parts, the root of herbaceous peony：20 parts, the rhizome of davallia：10 parts, Radix Angelicae Sinensis：15 parts, safflower：8 parts, wild lettuce：15
Part, smallflower beggarticks herb：10 parts, 15 parts of edible debregeasia root and leaf, 10 parts of black ancient tile, native copper：5 parts, notopterygium root：10 parts, Red Coppe：3 parts, pierce brain bag：2
Part.
4. the pharmaceutical composition of union is contributed to as claimed in claim 1, it is characterised in that：Including following component, it is
Weight portion：Pseudo-ginseng：30 parts, the bark of eucommia：25 parts, the root of herbaceous peony：30 parts, the rhizome of davallia：8 parts, Radix Angelicae Sinensis：22 parts, safflower：10 parts, wild lettuce：11
Part, smallflower beggarticks herb：15 parts, 12 parts of edible debregeasia root and leaf, 18 parts of black ancient tile, native copper：8 parts, notopterygium root：7 parts, Red Coppe：6 parts, pierce brain bag：5
Part.
5. the pharmaceutical composition of union is contributed to as claimed in claim 1, it is characterised in that：The pseudo-ginseng be chrysanthemum pseudo-ginseng or
At least one in Bulbilus boussingaultiae pseudobaselloidis.
6. a kind of preparation method of the pharmaceutical composition for contributing to union, it is characterised in that：It is comprised the following steps：
S1, takes claim 1-5 any one described pharmaceutical compositions, is soaked 2~4 hours with 3 times of boiling water of volume；
S2, add 5 times of volumes decocting boil 1-2 hours after filter；
The dregs of a decoction that step S2 is obtained are added 10 times of water of volume by S3, are filtered after decocting 0.5-1 hours；
S4, medicinal extract is condensed into by the filtrate merging of step S2 and step S3, centrifugation, filtrate, is carried out according to conventional preparation method
Processing, is made pharmaceutical preparation.
7. the pharmaceutical composition of union is contributed to as claimed in claim 6, it is characterised in that：The pharmaceutical preparation is external application
Preparation or oral formulations.
8. the pharmaceutical composition of union is contributed to as claimed in claim 6, it is characterised in that：The step S2 or/and step
Decocted described in rapid S3 first using being boiled by fire, then to be decocted slowly using slow fire.
9. the pharmaceutical composition of union is contributed to as claimed in claim 6, it is characterised in that：The step S2 or/and step
It is filtered into described in rapid S3 and is filtered while hot.
10. the pharmaceutical composition of union is contributed to as claimed in claim 6, it is characterised in that：Opening in the step S1
Coolant-temperature gage is 95 DEG C -100 DEG C.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611268085.7A CN106728043A (en) | 2016-12-31 | 2016-12-31 | It is a kind of to contribute to pharmaceutical composition of union and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611268085.7A CN106728043A (en) | 2016-12-31 | 2016-12-31 | It is a kind of to contribute to pharmaceutical composition of union and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106728043A true CN106728043A (en) | 2017-05-31 |
Family
ID=58952622
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611268085.7A Pending CN106728043A (en) | 2016-12-31 | 2016-12-31 | It is a kind of to contribute to pharmaceutical composition of union and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106728043A (en) |
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2016
- 2016-12-31 CN CN201611268085.7A patent/CN106728043A/en active Pending
Non-Patent Citations (2)
| Title |
|---|
| 刘国贵: "续骨散促进骨折愈合104例临床与实验研究", 《湖南中医杂志》 * |
| 纪辉煌等: "中西医结合治疗四肢骨折127例", 《福建医药杂志》 * |
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Application publication date: 20170531 |
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