CN106727980A - A kind of traditional Chinese powder medicine for nasal polyp and preparation method thereof - Google Patents

A kind of traditional Chinese powder medicine for nasal polyp and preparation method thereof Download PDF

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Publication number
CN106727980A
CN106727980A CN201611255234.6A CN201611255234A CN106727980A CN 106727980 A CN106727980 A CN 106727980A CN 201611255234 A CN201611255234 A CN 201611255234A CN 106727980 A CN106727980 A CN 106727980A
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nasal polyp
traditional chinese
powder medicine
chinese powder
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丁年生
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Wuwei County Shushan Large Horseshoe Planting Cooperatives
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Wuwei County Shushan Large Horseshoe Planting Cooperatives
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/62Nymphaeaceae (Water-lily family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/10Bryophyta (mosses)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268Asarum (wild ginger)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/538Schizonepeta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • A61K36/575Magnolia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/808Scrophularia (figwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966Fritillaria, e.g. checker lily or mission bells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers

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Abstract

The invention discloses a kind of traditional Chinese powder medicine for nasal polyp, its raw material includes by weight:Even must 25~35 parts of rhizoma nelumbinis, 17~23 parts of moss, 8~12 parts of the achene of Siberian cocklebur.Raw material also includes:The flower bud of lily magnolia, cloves, asarum, schizonepeta, windproof, peppermint, cape jasmine, radix scrophulariae, the bletilla striata, fritillaria.The invention also discloses the preparation method of the above-mentioned traditional Chinese powder medicine for nasal polyp.The present invention dissipates wind for the etiology and pathogenesis of nasal polyp with inducing diaphoresis, and cold dispelling is had one's ideas straightened out, stop blooding dispersing blood stasis, astringing to arrest bleeding, detumescence and promoting granulation, clearing heat and moistening lung, antipruritic effect of resolving sputum can be dispelled damp and hot, cleaning wind-heat evil poison, declares smooth lung qi, so that clearing the nasal passage, makes nasal polyp wither and fall certainly.

Description

A kind of traditional Chinese powder medicine for nasal polyp and preparation method thereof
Technical field
The present invention relates to technical field of traditional Chinese medicines, more particularly to a kind of traditional Chinese powder medicine for nasal polyp and preparation method thereof.
Background technology
Nasal polyp, is the superfluous lump for being born in nasal cavity or sinus mucosa upper process also known as rhinopolypus, is apt to occur in the lateral wall of nasal cavity And nose top.Nasal polyp can be caused to have a stuffy nose, breathe obstructed, or be opened and closed in flap valve sample;With dysosmia, have a headache, speak when The symptoms such as Hypernasality.
Nasal polyp is more to process Bo savoury because addiction is pungent usually, accumulates life damp and hot;On steam in lung, tie stagnant nose key;Or wind-heat evil poison Invasion and attack lung channel, lung qi must not be declared freely, caused by accumulation nose key.
The medicine of current clinical treatment nasal polyp is generally Western medicine and Chinese patent drug, and the western medicine course for the treatment of is long, and curative effect is slow, easily recurrence Etc. defect.
The content of the invention
Based on the technical problem that background technology is present, the present invention proposes a kind of traditional Chinese powder medicine and its system for nasal polyp Preparation Method, for the etiology and pathogenesis of nasal polyp, wind is dissipated with inducing diaphoresis, and cold dispelling is had one's ideas straightened out, dispersing blood stasis of stopping blooding, astringing to arrest bleeding, detumescence and promoting granulation, Clearing heat and moistening lung, antipruritic effect of resolving sputum can dispel damp and hot, cleaning wind-heat evil poison, smooth lung qi be declared, so that clearing the nasal passage, makes breath Meat is withered to fall certainly.
A kind of traditional Chinese powder medicine for nasal polyp proposed by the present invention, its raw material includes by weight:Even must rhizoma nelumbinis 25~ 35 parts, 17~23 parts of moss, 8~12 parts of the achene of Siberian cocklebur.
Preferably, its raw material also includes:The flower bud of lily magnolia, cloves, asarum, schizonepeta, windproof, peppermint, cape jasmine, radix scrophulariae, the bletilla striata, shellfish It is female.
Preferably, its raw material includes by weight:Even must 25~35 parts of rhizoma nelumbinis, 17~23 parts of moss, the achene of Siberian cocklebur 8~12 Part, 2~4 parts of the flower bud of lily magnolia, 2~4 parts of cloves, 3~5 parts of asarum, 4~6 parts of schizonepeta, windproof 2~4 parts, 7~9 parts of peppermint, cape jasmine 5~7 Part, 2~4 parts of radix scrophulariae, 2~4 parts of the bletilla striata, 2~4 parts of fritillaria.
Preferably, the flower bud of lily magnolia, cloves, asarum, schizonepeta, windproof weight ratio are 2.5~3.5:2.5~3.5:3.5~4.5: 4.5~5.5:2.5~3.5.
Preferably, peppermint, cape jasmine, radix scrophulariae, the bletilla striata, the weight ratio of fritillaria are 7.5~8.5:5.5~6.5:2.5~3.5: 2.5~3.5:2.5~3.5.
The preparation method of the above-mentioned traditional Chinese powder medicine for nasal polyp proposed by the present invention, raw material is placed in watt and is dried, so Grind into powder is obtained final product afterwards.
Powder is blown into the polyp surface in nasal cavity, daily 6~8 times, nasal polyp is withered to fall certainly.General 3~5 days i.e. more.
Even palpus rhizoma nelumbinis, sweet, puckery, mild-natured, returns stomach, Liver Channel, kidney channel.With hemostasis, effect of dispersing blood stasis.For spitting blood, Spitting of blood, hematuria, uterine bleeding.
The achene of Siberian cocklebur, bitter, sweet, pungent, warm in nature, mild toxicity.Enter lung, Liver Channel.With dispersing wind and cold, clearing the nasal passage, wind-damp dispelling is antipruritic Effect.Cure mainly nasosinusitis, anemofrigid headache, arthralgia pain due to rheumatism, rubella, eczema, mange.
The flower bud of lily magnolia, taste is pungent is warm in nature.Enter lung, stomach.With wind-dispelling, sensible effect.Headache is cured mainly, deep pool, obstructed, tooth of having a stuffy nose Bitterly.
Cloves, taste is pungent is warm in nature.Enter stomach, spleen, kidney channel.With middle benefit gas, warm kidney, inverse effect drops.Cure mainly hiccup, vomiting, anti- Stomach, dysentery, trusted subordinate's crymodynia, Xuan addictions, hernia, ringworm.
Asarum, taste is pungent is warm in nature.Enter lung, stomach.With wind-dispelling, cold dispelling, water-filling, the effect having one's ideas straightened out.Air-cooled headache is cured mainly, Nasosinusitis, dentalgia, phlegm and retained fluid coughs inverse, arthralgia pain due to rheumatism.
Schizonepeta, taste is pungent, slightly warm in nature.Return lung, Liver Channel.With the scattered wind of inducing diaphoresis, promoting eruption, disappear sore, effect of hemostasis.For feeling Emit, measles without adequate eruption, have blood in stool, uterine bleeding, nosebleed epistaxis.
It is windproof, taste is pungent, sweet, slightly warm in nature.Return bladder, liver, the spleen channel.With expelling pathogenic wind from the body surface, win wet analgesic, only effect of convulsion. Cure mainly diseases caused by external factors table card, rubella itch, arthralgia pain due to rheumatism, lockjaw.
Peppermint, taste is pungent is cool in nature.Enter lung, Liver Channel.With dispelling wind, radiating wards off dirty, effect of removing toxic substances.Cure mainly affection of exogenous wind-heat, Headache, hot eyes, abscess of throat, food stagnation inflatable, aphtha, toothache, sore scabies, urticaria.
Cape jasmine, bitter is cold in nature.The thoughts of returning home, lung, tri-jiao channel.With purging intense heat relieving restlessness, reducing fever and causing diuresis, effect of removing pattogenic heat from the blood and toxic material from the body.With In Vexed, jaundice urine is red, blood strangury and dry pain, blood-head tells nosebleed, red eye, swell pain, pathogenic fire,toxin and furuncles;Control bruise pain outward.
Radix scrophulariae is sweet, bitter, salty;Cold nature.Return lung, stomach, kidney channel.With clearing heat and cooling blood, purging intense heat and detonicating, effect of enriching yin. Cure mainly warm heresy to join the army, cave in pericardium, febrile virulent maculae, the deep red polydipsia of consumption of YIN caused by febrile disease, tongue, Tianjin hinder constipation, hectic fever due to yin labor is coughed, hot eyes, pharyngalgia, Scrofula, diphtheria, carbuncle sore tumefacting virus.
The bletilla striata, bitter, sweet, puckery, cold nature.Return lung, liver, stomach.With astringing to arrest bleeding, effect of detumescence and promoting granulation.For Hemoptysis is spitted blood, traumatism and bleeding, sore swollen toxin, chapped skin;Pulmonary tuberculosis hemoptysis, ulcer haemorrhage.
Fritillaria, bitter, sweet, cold nature.Return lung, the heart channel of Hang-Shaoyin.With clearing heat and moistening lung, effect of preventing phlegm from forming and stopping coughing.Coughed for lung heat Cough, the few phlegm of dry cough, deficiency of Yin labor is coughed, and coughs up sputum streaked with blood.
The present invention uses above-mentioned all medicines share, for the etiology and pathogenesis of nasal polyp, wind is dissipated with inducing diaphoresis, and cold dispelling is had one's ideas straightened out, only Blood dispersing blood stasis, astringing to arrest bleeding, detumescence and promoting granulation, clearing heat and moistening lung, antipruritic effect of resolving sputum can dispel damp and hot, cleaning wind-heat evil poison, a surname Smooth lung qi, so that clearing the nasal passage, makes nasal polyp wither and fall certainly.
Selection was diagnosed as the patient 120 of nasal polyp through outpatient service, using present invention treatment 7 days.Cure 113, effective 7 Example, cure rate reaches 94.17%, follow-up half a year, does not there is recurrence;There is not adverse reaction during treating in patient simultaneously.
Specific embodiment
Below, technical scheme is described in detail by specific embodiment.
Embodiment 1
A kind of traditional Chinese powder medicine for nasal polyp proposed by the present invention, its raw material includes by weight:Connect 30 parts of rhizoma nelumbinis of palpus, 20 parts of moss, 10 parts of the achene of Siberian cocklebur.
Embodiment 2
A kind of traditional Chinese powder medicine for nasal polyp proposed by the present invention, its raw material includes by weight:Connect 25 parts of rhizoma nelumbinis of palpus, 23 parts of moss, 8 parts of the achene of Siberian cocklebur, 4 parts of the flower bud of lily magnolia, 2 parts of cloves, 5 parts of asarum, 4 parts of schizonepeta, windproof 4 parts, 7 parts of peppermint, 7 parts of cape jasmine is profound 2 parts of ginseng, 4 parts of the bletilla striata, 2 parts of fritillaria.
Embodiment 3
A kind of traditional Chinese powder medicine for nasal polyp proposed by the present invention, its raw material includes by weight:Connect 35 parts of rhizoma nelumbinis of palpus, 17 parts of moss, 12 parts of the achene of Siberian cocklebur, 2 parts of the flower bud of lily magnolia, 4 parts of cloves, 3 parts of asarum, 6 parts of schizonepeta, windproof 2 parts, 9 parts of peppermint, 5 parts of cape jasmine, 4 parts of radix scrophulariae, 2 parts of the bletilla striata, 4 parts of fritillaria.
Embodiment 4
A kind of traditional Chinese powder medicine for nasal polyp proposed by the present invention, its raw material includes by weight:Connect 28 parts of rhizoma nelumbinis of palpus, 21 parts of moss, 9 parts of the achene of Siberian cocklebur, 3.5 parts of the flower bud of lily magnolia, 2.5 parts of cloves, 4.5 parts of asarum, 4.5 parts of schizonepeta, windproof 3.5 parts, peppermint 7.5 Part, 6.5 parts of cape jasmine, 2.5 parts of radix scrophulariae, 3.5 parts of the bletilla striata, 2.5 parts of fritillaria.
Embodiment 5
A kind of traditional Chinese powder medicine for nasal polyp proposed by the present invention, its raw material includes by weight:Connect 32 parts of rhizoma nelumbinis of palpus, 19 parts of moss, 11 parts of the achene of Siberian cocklebur, 2.5 parts of the flower bud of lily magnolia, 3.5 parts of cloves, 3.5 parts of asarum, 5.5 parts of schizonepeta, windproof 2.5 parts, peppermint 8.5 Part, 5.5 parts of cape jasmine, 3.5 parts of radix scrophulariae, 2.5 parts of the bletilla striata, 3.5 parts of fritillaria.
The preparation method of the above-mentioned traditional Chinese powder medicine for nasal polyp proposed by the present invention, raw material is placed in watt and is dried, so Grind into powder is obtained final product afterwards.
The above, the only present invention preferably specific embodiment, but protection scope of the present invention is not limited thereto, Any one skilled in the art the invention discloses technical scope in, technology according to the present invention scheme and its Inventive concept is subject to equivalent or change, should all be included within the scope of the present invention.

Claims (6)

1. a kind of traditional Chinese powder medicine for nasal polyp, it is characterised in that its raw material includes by weight:Even must rhizoma nelumbinis 25~35 Part, 17~23 parts of moss, 8~12 parts of the achene of Siberian cocklebur.
2. the traditional Chinese powder medicine of nasal polyp is used for according to claim 1, it is characterised in that its raw material also includes:The flower bud of lily magnolia, fourth Perfume, asarum, schizonepeta, windproof, peppermint, cape jasmine, radix scrophulariae, the bletilla striata, fritillaria.
3. the traditional Chinese powder medicine of nasal polyp is used for according to claim 2, it is characterised in that its raw material includes by weight:Even Must 25~35 parts of rhizoma nelumbinis, 17~23 parts of moss, 8~12 parts of the achene of Siberian cocklebur, 2~4 parts of the flower bud of lily magnolia, 2~4 parts of cloves, 3~5 parts of asarum, chaste tree 4~6 parts of mustard, windproof 2~4 parts, 7~9 parts of peppermint, 5~7 parts of cape jasmine, 2~4 parts of radix scrophulariae, 2~4 parts of the bletilla striata, 2~4 parts of fritillaria.
4. the traditional Chinese powder medicine of nasal polyp is used for according to Claims 2 or 3, it is characterised in that the flower bud of lily magnolia, cloves, asarum, chaste tree Mustard, windproof weight ratio are 2.5~3.5:2.5~3.5:3.5~4.5:4.5~5.5:2.5~3.5.
5. the traditional Chinese powder medicine of nasal polyp is used for according to claim any one of 2-4, it is characterised in that peppermint, cape jasmine, profound Ginseng, the bletilla striata, the weight ratio of fritillaria are 7.5~8.5:5.5~6.5:2.5~3.5:2.5~3.5:2.5~3.5.
6. it is a kind of as described in claim any one of 1-5 be used for nasal polyp traditional Chinese powder medicine preparation method, it is characterised in that will Raw material is placed in watt and to dry, and is then ground to powder and obtains final product.
CN201611255234.6A 2016-12-30 2016-12-30 A kind of traditional Chinese powder medicine for nasal polyp and preparation method thereof Withdrawn CN106727980A (en)

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Country Status (1)

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Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
赵建成: "《段凤舞肿瘤积验方》", 30 September 1991, 安徽科学技术出版社 *

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Application publication date: 20170531