CN106727246A - Calf serum cell nutrient solution - Google Patents

Calf serum cell nutrient solution Download PDF

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Publication number
CN106727246A
CN106727246A CN201710069327.8A CN201710069327A CN106727246A CN 106727246 A CN106727246 A CN 106727246A CN 201710069327 A CN201710069327 A CN 201710069327A CN 106727246 A CN106727246 A CN 106727246A
Authority
CN
China
Prior art keywords
calf serum
nutrient solution
growth factor
hyaluronic acid
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710069327.8A
Other languages
Chinese (zh)
Inventor
徐冰
周国瑜
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shanghai Yuan Yuan Biotechnology Co Ltd
Original Assignee
Shanghai Yuan Yuan Biotechnology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Yuan Yuan Biotechnology Co Ltd filed Critical Shanghai Yuan Yuan Biotechnology Co Ltd
Priority to CN201710069327.8A priority Critical patent/CN106727246A/en
Publication of CN106727246A publication Critical patent/CN106727246A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/981Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
    • A61K8/983Blood, e.g. plasma
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

Abstract

The present invention provides a kind of calf serum cell nutrient solution, including calf serum, epithelical cell growth factor and hyaluronic acid;The percent by volume of each composition is:Calf serum:70 95%;Epithelical cell growth factor:1 10%;Hyaluronic acid:1 30%.After the technical program, arranged in pairs or groups by the reasonable combination of three of the above composition, comprehensive maintenance and regulation scientifically is carried out in face of cell from cytotrophy, growth, reparation tripartite in process of tissue reparation, shortening repair time is reached, accelerates the purpose of skin repair.

Description

Calf serum cell nutrient solution
Technical field
The present invention relates to repair class cosmetic field, more particularly to a kind of calf serum cell nutrient solution.
Background technology
The existing main component for repairing product is epithelical cell growth factor, and epithelical cell growth factor is to promoting into fiber The metabolism of cell and the formation of collagen play critical function, can promote the growth and breeding of skin histology, on regulation and control skin The division of skin, endothelium and stroma cell, breeding and Growth and Differentiation, promote cell metabolism and growth.
Because epithelical cell growth factor single can only play a part of cell growth, therefore user is produced using such reparation Product find following problem using process:1st, the cycle repaired and grow is relatively long.2nd, nutritional ingredient is single, and limitation is larger, Various demands of user can not be met.
The content of the invention
In order to solve the deficiency of prior art presence, the present invention provides a kind of polynary nutritional ingredient, reparation and growth cycle Relatively short calf serum cell nutrient solution.
To achieve these goals, the technical scheme of present invention offer is:A kind of calf serum cell nutrient solution, including it is small Cow's serum, epithelical cell growth factor and hyaluronic acid;The percent by volume of each composition is:Calf serum:70-95%;Epidermis Porcine HGF:1-10%;Hyaluronic acid:1-30%.
After the technical program, calf serum:Rich in 70% inorganic substances, such as electrolyte and various necessary micro units Element, and 30% organic substance, such as oligosaccharides, nucleic acid derivative, amino acid, low molecular polypeptide, glycolipid class and sugar and lipid metabolism Intermediate product etc., by promoting intake and utilization of the cell to glucose, increase intake and utilization of the cell to supporting so that Atriphos generation increases, and improves cellular energy, increases with energy requirement in the case where function defect, metabolism are suppressed When, promote cellular energy metabolism, improvement cell function, enhancing repair in cellular level.
Hyaluronic acid:It is a kind of high molecular polymer, is shown in body with its unique molecular structure and physicochemical property Regulatory protein matter, Water-Electrolyte diffusion and operating are shown, promote wound healing etc., it is most important that sodium hyaluronate has special guarantor Water is acted on, and water is the source of all things on earth, and the distinctive water retaining function of hyaluronic acid plays vital effect during cell repair.
By three of the above reasonable composition combine arrange in pairs or groups, calf serum cell nutrient solution in process of tissue reparation scientifically Comprehensive maintenance and regulation is carried out in face of cell from cytotrophy, growth, reparation tripartite, shortening repair time is reached, accelerated The purpose of skin repair.
Specific embodiment
Preferred embodiments of the present invention are further elaborated below:
Implementation method one
A kind of calf serum cell nutrient solution, including calf serum, epithelical cell growth factor and hyaluronic acid;Each composition Percent by volume be:Calf serum:82%;Epithelical cell growth factor:6%;Hyaluronic acid:12%.
Implementation method two
A kind of calf serum cell nutrient solution, including calf serum, epithelical cell growth factor and hyaluronic acid;Each composition Percent by volume be:Calf serum:70%;Epithelical cell growth factor:1%;Hyaluronic acid:29%.
Implementation method three
A kind of calf serum cell nutrient solution, including calf serum, epithelical cell growth factor and hyaluronic acid;Each composition Percent by volume be:Calf serum:95%;Epithelical cell growth factor:3%;Hyaluronic acid:7%.
Implementation method four
A kind of calf serum cell nutrient solution, including calf serum, epithelical cell growth factor and hyaluronic acid;Each composition Percent by volume be:Calf serum:80%;Epithelical cell growth factor:7%;Hyaluronic acid:13%.
Implementation method five
A kind of calf serum cell nutrient solution, including calf serum, epithelical cell growth factor and hyaluronic acid;Each composition Percent by volume be:Calf serum:85%;Epithelical cell growth factor:4%;Hyaluronic acid:11%.
In order to fully demonstrate technical scheme and other reparation class differences and superiority, patient 900 is now chosen Clinical data, at 18-50 Sui, the surface of a wound is located at 480, face to patient age, four limbs 250, trunk 170, the surface of a wound to spread or The sheet of aggregation is distributed, and area is:2.5 X of X 1.0cm to 5.0 3.0cm differ in size.
Note:Surface of a wound area X before surface of a wound relaxation shrinkage (%)=(surface of a wound area after surface of a wound area-medication before medication)/medication 100%.
The present invention is not limited to above-mentioned preferred forms, and anyone can show that other are various under enlightenment of the invention The product of form, however, make any change in its shape or structure, it is every with skill identical or similar to the present application Art scheme, is within the scope of the present invention.

Claims (3)

1. a kind of calf serum cell nutrient solution, it is characterised in that:Including calf serum, epithelical cell growth factor and hyalomitome Acid;The percent by volume of each composition is:Calf serum:70-95%;Epithelical cell growth factor:1-10%;Hyaluronic acid:1- 30%.
2. calf serum cell nutrient solution according to claim 1, it is characterised in that:The percent by volume of each composition is: Calf serum:80-85%;Epithelical cell growth factor:4-7%;Hyaluronic acid:10-20%.
3. calf serum cell nutrient solution according to claim 2, it is characterised in that:The percent by volume of each composition is: Calf serum:82%;Epithelical cell growth factor:6%;Hyaluronic acid:12%.
CN201710069327.8A 2017-02-08 2017-02-08 Calf serum cell nutrient solution Pending CN106727246A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710069327.8A CN106727246A (en) 2017-02-08 2017-02-08 Calf serum cell nutrient solution

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710069327.8A CN106727246A (en) 2017-02-08 2017-02-08 Calf serum cell nutrient solution

Publications (1)

Publication Number Publication Date
CN106727246A true CN106727246A (en) 2017-05-31

Family

ID=58956351

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201710069327.8A Pending CN106727246A (en) 2017-02-08 2017-02-08 Calf serum cell nutrient solution

Country Status (1)

Country Link
CN (1) CN106727246A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108635569A (en) * 2018-06-14 2018-10-12 天津市正江现代生物技术有限公司 A kind of small Swine serum cell nutrient solution

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN85102921A (en) * 1985-04-05 1986-10-08 菲地亚有限公司 Preparation has pharmaceutically-active hyaluronic acid component and contains the method for the medicine of this component
CN1335135A (en) * 2000-07-25 2002-02-13 凌沛学 Artificial skin powder prepn containing sodium hyaluronate and its prepn
CN1337270A (en) * 2000-08-07 2002-02-27 黄玲惠 Wound dressing and its prepn.
CN1586457A (en) * 2004-07-09 2005-03-02 何玉兰 Compound active biological factor beauty liquid
CN1640491A (en) * 2004-01-15 2005-07-20 方昌阁 Recombinant human epidermal growth factor compound biological agent and its use
CN1676602A (en) * 2004-04-02 2005-10-05 天津市天津医院 Skin cell with anti-inflammatory activity, and its preparing method and use for skin infective wound surface
CN1800372A (en) * 2005-12-02 2006-07-12 王平安 Engineered extracellular matrix preparation method
CN1939288A (en) * 2006-08-10 2007-04-04 河北医科大学口腔医院 Composite acne-inhibiting pellicle
CN102839205A (en) * 2012-08-21 2012-12-26 任杰 Method for preparing oligopeptide epidermis cell growth factor dry powder
CN102861320A (en) * 2011-07-08 2013-01-09 上海昊海生物科技股份有限公司 Spray for treating skin and mucosa wounds
CN104840428A (en) * 2014-02-13 2015-08-19 山东省生物医药科学院 Hyaluronic acid-chitosan microsphere carrying epidermal growth factor and preparation method and application of hyaluronic acid-chitosan microsphere

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN85102921A (en) * 1985-04-05 1986-10-08 菲地亚有限公司 Preparation has pharmaceutically-active hyaluronic acid component and contains the method for the medicine of this component
CN1335135A (en) * 2000-07-25 2002-02-13 凌沛学 Artificial skin powder prepn containing sodium hyaluronate and its prepn
CN1337270A (en) * 2000-08-07 2002-02-27 黄玲惠 Wound dressing and its prepn.
CN1640491A (en) * 2004-01-15 2005-07-20 方昌阁 Recombinant human epidermal growth factor compound biological agent and its use
CN1676602A (en) * 2004-04-02 2005-10-05 天津市天津医院 Skin cell with anti-inflammatory activity, and its preparing method and use for skin infective wound surface
CN1586457A (en) * 2004-07-09 2005-03-02 何玉兰 Compound active biological factor beauty liquid
CN1800372A (en) * 2005-12-02 2006-07-12 王平安 Engineered extracellular matrix preparation method
CN1939288A (en) * 2006-08-10 2007-04-04 河北医科大学口腔医院 Composite acne-inhibiting pellicle
CN102861320A (en) * 2011-07-08 2013-01-09 上海昊海生物科技股份有限公司 Spray for treating skin and mucosa wounds
CN102839205A (en) * 2012-08-21 2012-12-26 任杰 Method for preparing oligopeptide epidermis cell growth factor dry powder
CN104840428A (en) * 2014-02-13 2015-08-19 山东省生物医药科学院 Hyaluronic acid-chitosan microsphere carrying epidermal growth factor and preparation method and application of hyaluronic acid-chitosan microsphere

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
张瑶华等: "《中国常用药品集》", 30 June 2006, 上海交通大学出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108635569A (en) * 2018-06-14 2018-10-12 天津市正江现代生物技术有限公司 A kind of small Swine serum cell nutrient solution

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CB03 Change of inventor or designer information

Inventor after: Xu Bing

Inventor before: Xu Bing

Inventor before: Zhou Guoyu

CB03 Change of inventor or designer information
RJ01 Rejection of invention patent application after publication

Application publication date: 20170531

RJ01 Rejection of invention patent application after publication