CN106726647A - Antimicrobial spume hand cleanser and preparation method thereof - Google Patents
Antimicrobial spume hand cleanser and preparation method thereof Download PDFInfo
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- CN106726647A CN106726647A CN201710087652.7A CN201710087652A CN106726647A CN 106726647 A CN106726647 A CN 106726647A CN 201710087652 A CN201710087652 A CN 201710087652A CN 106726647 A CN106726647 A CN 106726647A
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- hand cleanser
- stirring
- antimicrobial spume
- spume
- antimicrobial
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/27—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/732—Starch; Amylose; Amylopectin; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- Detergent Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Cosmetics (AREA)
Abstract
The present invention relates to a kind of antimicrobial spume hand cleanser including nanometer zinc compound bactericide and preparation method thereof.Antimicrobial spume hand cleanser of the invention has outstanding bactericidal effect and low-down skin irritation, can be widely applied to the antibacterial of skin and body surface in daily life, antibacterial, sterilization.
Description
Technical field
The invention belongs to sterile products technical field, and in particular to a kind of antimicrobial spume hand cleanser, and preparation method thereof.
Background technology
Antibacterial includes antibacterial, sterilizing, sterilized, mould proof, anti-corrosion.Bacterium is killed using chemically or physically method or is prevented thin
The process of bacteria growing breeding is the general name of antibacterial.Antiseptic is can to make certain micro-organisms within a certain period of time（Bacterium, fungi,
Saccharomycete, algae and virus etc.）Growth or breeding be maintained at necessary chemical substance below horizontal.
Antiseptic is broadly divided into organic antibacterial agent, inorganic antiseptic and natural antibacterial agent.Organic antibacterial agent anti-microbial property is high,
Sterilization speed is fast, but to environment and human body is harmful and working life is short, poor heat resistance；Natural antibacterial agent antimicrobial efficiency is high, peace
Atoxic, but processing difficulties, poor heat resistance.Inorganic antiseptic is because its effective antibacterial phase is long, the good, has a broad antifungal spectrum of heat resistance etc.
Feature turns into the class antiseptic being most widely used.
In inorganic antiseptic, at most, purposes is most for the inorganic salts of metal ion or the inorganic antiseptic kind of complex compound
Extensively, at most, wherein antibiotic property size is ordered as yield：Hg>Ag>Cd>Cu>Zn>Fe>Ni etc., but be with antibiotic property only
Inadequate, also requiring that it can not be damaged to human body, the metal such as Hg, Cd, Pb also has antibacterial ability, but harmful.
The security of metal ion is ordered as：Ag>Co>Ni>Al>Zn>Cu=Fe>Mn>Sn>Ba>Mg>Ca, so with regard to security and antibacterial
Property the common result for considering, next to that Cu systems and Zn systems, therefore these three with inorganic compound as carrier with Ag ions preferably
Inorganic antiseptic is obtained a wide range of applications.But, Cu ions carry color because of itself, can influence the expressive force of product；Silver
Because its easy oxidation discoloration, it is expensive, easily reunite the problems such as, be restricted using scope.
Metallic zinc is the 1/1000 of argent due to the antibacterial ability of itself, causes most of research institutions and manufacturer
All energy is concentrated in the modified research and development of Ag and Nano Silver to improve it as the performance of antiseptic, so as to have ignored zinc conduct
The plurality of advantages of antiseptic, studies seldom it.In fact, Nano-Zinc antiseptic can overcome nano silver antimicrobials actually should
Many defects in, such as easily oxidation, blackening, expensive, difficult dispersion, and possess significant antibacterial effect, significantly
Extend antibacterial ageing, especially can relatively easily be scattered in corresponding product, such as plastics, textile fabric, slurry,
Waterborne liquid, oil soluble liquid, greatly extend range of application.Therefore, research and development Nano-Zinc antiseptic can be greatly
Meet social desirability.
Within past a very long time, sanitary washing is used as commonly using soap, perfumed soap in people's daily life
Articles for use.Though soap, perfumed soap easily slide when in use with good dirt-removing power, meeting water and high temperature can soften and nature
Consumption, soap, perfumed soap can make dry skin in alkalescence after cleaning, lack gloss, and soap, perfumed soap are sterilized in cleaning process
Effect is limited, and is bound to be infected with dirt on hand and bacterium after use, produces secondary pollution, and antimicrobial spume hand cleanser
With antibacterial, skin care, using and effect easy to clean etc..Recently as growth in the living standard, people's consumption idea
Change therewith, it is also proposed demand higher to hygiene, antimicrobial spume hand cleanser daily washes clean use as one kind is new
Product are more and more received by consumer.
The species of antimicrobial spume hand cleanser on the market is less at present, and is used mostly the organic anti-bacterials such as chlorine system, alcohols
Agent, this kind of antiseptic is easily caused the resistance to the action of a drug and anaphylactoid generation in varying degrees, and has that action time is short, bactericidal range
The defect such as narrow.
The content of the invention
To solve the problems of above-mentioned hand cleanser of antimicrobial spume in the prior art, the present invention proposes a kind of including receiving
Antimicrobial spume hand cleanser of rice zinc compound bactericide and preparation method thereof, antimicrobial spume hand cleanser of the invention has outstanding killing
Bacterium effect and low-down skin irritation, can be widely applied to skin and body surface in daily life antibacterial, it is antibacterial, disappear
Poison.
In an aspect, the present invention relates to a kind of antimicrobial spume hand cleanser, it is grouped by each group of following mass percent
Into：Nanometer zinc compound bactericide 0.5% ~ 10%, surfactant 5% ~ 15%, emollient 0.1% ~ 10%, pH adjusting agent 0% ~ 0.5%,
Essence 0% ~ 0.5%, balance of deionized water.
In a preferred embodiment, the content of the essence is not zero.
In a preferred embodiment, the content of the pH adjusting agent is not zero.
Surfactant is preferably selected from AES, sodium lauroyl sarcosine, CAB, cocoanut fatty acid diethanolamide
（6501）, one or more in AES-3EO and CMEA.
Emollient is preferably selected from glycerine, dimethicone, aloe, vitamin E, propane diols, Sodium Hyaluronate and olive
One or more in oil.
PH adjusting agent is preferably selected from one or more in citric acid, potassium citrate, triethanolamine and lactic acid.
In a preferred embodiment, described antimicrobial spume hand cleanser is grouped into by each group of following mass percent：
Nanometer zinc compound bactericide 1%, CAB 6%, sodium lauroyl sarcosine 3%, glycerine 2%, essence 0.01%, deionized water 87.99%.
In another aspect, the present invention relates to the preparation method of the antimicrobial spume hand cleanser, comprise the following steps：
（1）The nanometer zinc compound bactericide of formula rate amount is added in reactor, the deionized water of formula ratio is subsequently added
Stirring 3-10min；Preferably 4-6min；More preferably 5min；
（2）Add the surfactant of formula ratio while stirring, stirring is to well mixed；
（3）Sequentially add emollient, the essence of formula ratio under stirring, stirring is allowed to dissolve, and stir to well mixed；
（4）Add pH adjusting agent while stirring, stirring is to well mixed；Obtain described antimicrobial spume hand cleanser.
In a preferred embodiment, pH adjusting agent adjusts to 6-8 the pH value of mixed liquor.
Nanometer zinc compound bactericide of the invention and preparation method thereof for example may refer to Chinese patent application CN
201510532442.5, entire contents are incorporated herein here by reference.
Specific embodiment
Embodiments of the invention will hereafter be conducted further description, wherein, each embodiment is only the exemplary present invention
Implementation method, it is not intended to constitute limiting the scope of the invention.Those skilled in the art can according to explanation above with
And following description of the embodiments makes various different improvement and deformation, it is without departing from spirit and substance of the present invention.
Accordingly, the scope of the present invention is intended merely to be defined by every claim scope required for protection.
Embodiment 1
Antimicrobial spume hand cleanser of the invention prepares as follows：（1）1g nanometers of zinc compound bactericide is added in reactor, then
Add 87.99g deionized waters stirring 5min；（2）6g CAB and 3g sodium lauroyl sarcosines, stirring to mixing are added while stirring
Uniformly；（3）Sequentially add 2g glycerine and 0.01g essence under stirring, stirring is allowed to dissolve, and stir to well mixed；
Obtain described antimicrobial spume hand cleanser.
Embodiment 2
Antimicrobial spume hand cleanser of the invention prepares as follows：（1）1g nanometers of zinc compound bactericide is added in reactor, then
Add 86.98g deionized waters stirring 5min；（2）Add 10g CAB and 1g sodium lauroyl sarcosines while stirring, stirring is to mixed
Close uniform；（3）1g glycerine and 0.02g essence are sequentially added under stirring, stirring is allowed to dissolve, and stir equal to mixing
It is even；Obtain described antimicrobial spume hand cleanser.
Embodiment 3
Antimicrobial spume hand cleanser of the invention prepares as follows：（1）1g nanometers of zinc compound bactericide is added in reactor, then
Add 90.69g deionized waters stirring 3min；（2）5g CAB and 2g sodium lauroyl sarcosines, stirring to mixing are added while stirring
Uniformly；（3）1.3g glycerine and 0.01g essence are sequentially added under stirring, stirring is allowed to dissolve, and stir equal to mixing
It is even；Obtain described antimicrobial spume hand cleanser.
Embodiment 4
Antimicrobial spume hand cleanser of the invention prepares as follows：（1）0.5g nanometers of zinc compound bactericide is added in reactor, with
74g deionized waters stirring 8min is added afterwards；（2）10g AES and 5g cocoanut fatty acid diethanolamides are added while stirring, are stirred
Mix to well mixed；（3）10g dimethicones and 0.5g essence are sequentially added under stirring, stirring is allowed to dissolve, and stirs
Mix to well mixed；Obtain described antimicrobial spume hand cleanser.
Embodiment 5
Antimicrobial spume hand cleanser of the invention prepares as follows：（1）10g nanometers of zinc compound bactericide is added in reactor, with
84.2g deionized waters stirring 10min is added afterwards；（2）2.6g AES-3EO and 2.4g CAB, stirring to mixing are added while stirring
Uniformly；（3）0.5g vitamin Es and 0.3g essence are sequentially added under stirring, stirring is allowed to dissolve, and stir equal to mixing
It is even；Obtain described antimicrobial spume hand cleanser.
Claims (10)
1. a kind of antimicrobial spume hand cleanser, it is characterised in that be grouped into by each group of following mass percent：Nano-Zinc is compound anti-
Microbial inoculum 0.5% ~ 10%, surfactant 5% ~ 15%, emollient 0.1% ~ 10%, pH adjusting agent 0% ~ 0.5%, essence 0% ~ 0.5%, surplus
It is deionized water.
2. antimicrobial spume hand cleanser according to claim 1, it is characterised in that：The content of the essence is not zero.
3. antimicrobial spume hand cleanser according to claim 1, it is characterised in that：The content of the pH adjusting agent is not zero.
4. the antimicrobial spume hand cleanser according to any one of claims 1 to 3, it is characterised in that：Surfactant is selected from
AES, sodium lauroyl sarcosine, CAB, cocoanut fatty acid diethanolamide（6501）, one kind or many in AES-3EO and CMEA
Kind.
5. the antimicrobial spume hand cleanser according to any one of Claims 1-4, it is characterised in that：Emollient is selected from glycerine, two
One or more in methyl-silicone oil, aloe, vitamin E, propane diols, Sodium Hyaluronate and olive oil.
6. the antimicrobial spume hand cleanser according to any one of claim 1 to 5, it is characterised in that：PH adjusting agent is selected from lemon
One or more in acid, potassium citrate, triethanolamine and lactic acid.
7. antimicrobial spume hand cleanser according to claim 1, it is characterised in that described antimicrobial spume hand cleanser is by as follows
The each group of mass percent is grouped into：Nanometer zinc compound bactericide 1%, CAB 6%, sodium lauroyl sarcosine 3%, glycerine 2%, essence
0.01%th, deionized water 87.99%.
8. the preparation method of the antimicrobial spume hand cleanser according to any one of claim 1 to 7, it is characterised in that including following
Step：
（1）The nanometer zinc compound bactericide of formula rate amount is added in reactor, the deionized water of formula ratio is subsequently added
Stirring 3-10min；
（2）Add the surfactant of formula ratio while stirring, stirring is to well mixed；
（3）Sequentially add emollient, the essence of formula ratio under stirring, stirring is allowed to dissolve, and stir to well mixed；
（4）Add pH adjusting agent while stirring, stirring is to well mixed；Obtain described antimicrobial spume hand cleanser.
9. preparation method according to claim 8, it is characterised in that：PH adjusting agent adjusts to 6-8 the pH value of mixed liquor.
10. preparation method according to claim 8 or claim 9, it is characterised in that：Step（1）Mixing time be 4-6min；It is excellent
Elect 5min as.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710087652.7A CN106726647A (en) | 2017-02-17 | 2017-02-17 | Antimicrobial spume hand cleanser and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201710087652.7A CN106726647A (en) | 2017-02-17 | 2017-02-17 | Antimicrobial spume hand cleanser and preparation method thereof |
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| Publication Number | Publication Date |
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| CN106726647A true CN106726647A (en) | 2017-05-31 |
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| CN201710087652.7A Pending CN106726647A (en) | 2017-02-17 | 2017-02-17 | Antimicrobial spume hand cleanser and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107213033A (en) * | 2017-06-12 | 2017-09-29 | 南京凯创协同纳米技术有限公司 | Transparent gel type anti-acne mildy wash and preparation method thereof |
| CN108271807A (en) * | 2018-02-05 | 2018-07-13 | 南京凯创协同纳米技术有限公司 | Travelling antimicrobial spray |
| CN111481468A (en) * | 2020-05-25 | 2020-08-04 | 浙江美生日化用品有限公司 | Foam disinfection hand sanitizer and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104840378A (en) * | 2015-05-28 | 2015-08-19 | 南阳市汇博生物技术有限公司 | Skin-care sterilization hand sanitizer and preparation method thereof |
| CN105191936A (en) * | 2015-08-26 | 2015-12-30 | 徐良 | Nano-zinc antimicrobial compound and preparation method and application thereof |
| CN105748361A (en) * | 2016-03-24 | 2016-07-13 | 攀柔莎（江苏）生物科技股份有限公司 | Hand sanitizer for children |
-
2017
- 2017-02-17 CN CN201710087652.7A patent/CN106726647A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104840378A (en) * | 2015-05-28 | 2015-08-19 | 南阳市汇博生物技术有限公司 | Skin-care sterilization hand sanitizer and preparation method thereof |
| CN105191936A (en) * | 2015-08-26 | 2015-12-30 | 徐良 | Nano-zinc antimicrobial compound and preparation method and application thereof |
| CN105748361A (en) * | 2016-03-24 | 2016-07-13 | 攀柔莎（江苏）生物科技股份有限公司 | Hand sanitizer for children |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107213033A (en) * | 2017-06-12 | 2017-09-29 | 南京凯创协同纳米技术有限公司 | Transparent gel type anti-acne mildy wash and preparation method thereof |
| CN108271807A (en) * | 2018-02-05 | 2018-07-13 | 南京凯创协同纳米技术有限公司 | Travelling antimicrobial spray |
| CN111481468A (en) * | 2020-05-25 | 2020-08-04 | 浙江美生日化用品有限公司 | Foam disinfection hand sanitizer and preparation method thereof |
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Application publication date: 20170531 |