CN106726101B - A kind of wax therapy Chinese medicine wax stone and preparation method thereof - Google Patents

A kind of wax therapy Chinese medicine wax stone and preparation method thereof Download PDF

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CN106726101B
CN106726101B CN201710018159.XA CN201710018159A CN106726101B CN 106726101 B CN106726101 B CN 106726101B CN 201710018159 A CN201710018159 A CN 201710018159A CN 106726101 B CN106726101 B CN 106726101B
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parts
layer
wax
melt adhesive
hot melt
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CN106726101A (en
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张小林
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Zhengzhou Purple Forest Biotechnology Co Ltd
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Zhengzhou Purple Forest Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00Heating or cooling appliances for medical or therapeutic treatment of the human body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/55Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/15Pinaceae (Pine family), e.g. pine or cedar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/328Commiphora, e.g. mecca myrrh or balm of Gilead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/39Convolvulaceae (Morning-glory family), e.g. bindweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/43Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/487Psoralea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714Aconitum (monkshood)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/716Clematis (leather flower)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/889Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents

Abstract

The present invention relates to medical health care products technical fields, and in particular to a kind of wax therapy Chinese medicine wax stone includes beeswax layer, rosin hot melt adhesive Chinese traditional medicine layer and crystallite wax layer from inside to outside;Rosin hot melt adhesive Chinese traditional medicine layer is prepared from the following raw materials:Hot melt adhesive, traditional Chinese medicine powder, rosin, bleeding agent;Beeswax layer with a thickness of 4 ~ 6mm, rosin hot melt adhesive Chinese traditional medicine layer with a thickness of 6 ~ 8mm, crystallite wax layer with a thickness of 7 ~ 9mm.Wax stone of the present invention is neutrality with a thickness of 17 ~ 23mm, PH, and oil content is low(3%), hardness is moderate(Needle penetration 15mm), poor thermal conductivity, thermal capacity is big, a large amount of heat is absorbed when it is melted, slowly releases heat when cooling, and heat dissipation is slow, soaking time is long, can effectively drive away the induced pain factor, diminish inflammation, delay joint ageing speed, QI invigorating righting, YIN and YANG balance regulating, thoroughly in expression, the promoting flow of qi and blood circulation, to achieve the purpose that dispelling disease.

Description

A kind of wax therapy Chinese medicine wax stone and preparation method thereof
Technical field
The present invention relates to medical health care products technical fields, and in particular to a kind of wax therapy Chinese medicine wax stone and its preparation side Method.
Background technique
Wax therapy is the new opplication of middle traditional thermotherapy, replaces hydro-thermal to apply using wax, i.e., it is solid wax water proof to be heated into half The wax stone of state, which is applied, carries out thermal therapy in disease sites.Since wax is high relative to the thermal capacity of water, thermal coefficient is small, radiates the time It is long, and can be in close contact with physical feeling, keep the local organization for sticking place heated, blood vessel dilatation, circulation is accelerated, cell permeability Increase, therefore be clinically usually used in pain caused by treating wind, cold, wet numbness, there are the curative effects such as analgesic, detumescence, anti-inflammatory.Currently, Base-material used in wax therapy is mostly single medical paraffin, although this paraffin thermal coefficient is small, can keep heat for a long time Amount, but its flexibility is poor, frangible, heat dissipation is uneven, and it sticks on generation contraction after the hot wax on human body cool off and becomes very crisp, hard, Patient can feel extremely uncomfortable because of tightening for skin.And wax therapy traditional at present is all to carry out list with the wax of one-component The effect of thermotherapy is only realized in pure hot compress, does not have medication effect.
For defect existing for traditional wax therapy raw material is overcome, there is the research and development of some innovations, such as China Patent CN104474554A discloses the formula and preparation method of a kind of wax therapy extrusion wax, passes through beeswax, medical yellow wax, pine It is fragrant, to the right, vaseline, bleeding agent and volcanic mineral mud be used in mixed way, improve moulding and the osmotic effect of wax mud, but the wax The heat insulation effect and Medicated Permeation effect of mud are still unable to meet demand.
Summary of the invention
In order to overcome the drawbacks of the prior art, an object of the present invention is to provide a kind of wax therapy Chinese medicine wax stone, has Good flexibility and plasticity can be in close contact with skin, and thermal conductivity is small, and heat dissipation is slow, and soaking time is long, and controls with drug Treat health-care efficacy.
Meanwhile the object of the invention is also to provide a kind of wax therapy preparation methods of Chinese medicine wax stone.
In order to achieve the goal above, the technical scheme adopted by the invention is that:
A kind of wax therapy Chinese medicine wax stone so that the used time close to patient skin be internal layer, from inside to outside successively include beeswax layer, Rosin hot melt adhesive Chinese traditional medicine layer and crystallite wax layer;Wherein rosin hot melt adhesive Chinese traditional medicine layer is prepared by following raw material in parts by weight: 90 ~ 110 parts of hot melt adhesive, 45 ~ 55 parts of traditional Chinese medicine powder, 4 ~ 6 parts of rosin, 1 ~ 2 part of bleeding agent;
With every part of traditional Chinese medicine powder for an entirety, the traditional Chinese medicine powder is made of the raw material of following parts by weight:Aconiti preparata,radix 55 ~ 65 Part, 55 ~ 65 parts of wild aconite root, 45 ~ 55 parts of the root of Chinese clematis, 45 ~ 55 parts of gentianae macrophyllae, 45 ~ 55 parts of lycopodium calvatum, 45 ~ 55 parts of lopseed, psoralea corylifolia 45 ~ 55 parts, 45 ~ 55 parts of Semen Cuscutae, 45 ~ 55 parts of radix achyranthis bidentatae, 45 ~ 55 parts of cortex cinnamomi, 55 ~ 65 parts of olibanum, 55 ~ 65 parts of myrrh, dragon's blood 45 ~ 55 parts, 8 ~ 12 parts of Moschus;
Optionally, the beeswax layer with a thickness of 4 ~ 6mm, rosin hot melt adhesive Chinese traditional medicine layer with a thickness of 6 ~ 8mm, crystallite wax layer With a thickness of 7 ~ 9mm.
Optionally, the bleeding agent is by azone, house oil and Marmot oil according to mass ratio 3 ~ 5:2~3:1 ~ 2 composition.
Optionally, the bleeding agent is by azone, house oil and Marmot oil according to mass ratio 4:3:2 compositions.
Optionally, the hot melt adhesive is one of hot-fusible pressure-sensitive adhesive, polyamide hot, EVA hot-melt adhesive or any group It closes
Preferably, rosin hot melt adhesive Chinese traditional medicine layer is prepared by following raw material in parts by weight:100 parts of hot melt adhesive, Chinese medicine 50 parts of powder, 5 parts of rosin, 1.5 parts of bleeding agent;
With every part of traditional Chinese medicine powder for an entirety, the traditional Chinese medicine powder is made of the raw material of following parts by weight:60 parts of aconiti preparata,radix, 60 parts of wild aconite root, 50 parts of the root of Chinese clematis, 50 parts of gentianae macrophyllae, 50 parts of lycopodium calvatum, 50 parts of lopseed, 50 parts of psoralea corylifolia, 50 parts of Semen Cuscutae, ox 50 parts of knee, 50 parts of cortex cinnamomi, 60 parts of olibanum, 60 parts of myrrh, 50 parts of dragon's blood, 10 parts of Moschus;
The beeswax layer with a thickness of 5mm, rosin hot melt adhesive Chinese traditional medicine layer with a thickness of 7mm, crystallite wax layer with a thickness of 8mm。
The preparation method of above-mentioned wax therapy Chinese medicine wax stone, including following operating procedure:
1)Prepare beeswax layer:It takes beeswax heating and melting at liquid, pours into wax stone molding die, shape after liquid beeswax is cooling At the beeswax layer with a thickness of 4 ~ 6mm;
2)Prepare rosin hot melt adhesive Chinese traditional medicine layer:It takes each Chinese medicine material to be ground into powder-mixed uniform, obtains traditional Chinese medicine powder;Take heat Melten gel and rosin Hybrid Heating melt to semi-fluid condition, and traditional Chinese medicine powder then is added and bleeding agent is mixed evenly in paste Paste is uniformly spread out in step 1 by object)The top of the beeswax layer of preparation forms the pine with a thickness of 6 ~ 8mm in the top of beeswax layer Fragrant hot melt adhesive Chinese traditional medicine layer;
3)Prepare crystallite wax layer:It takes microwax heating and melting at liquid, is poured on step 2)Middle rosin hot melt adhesive Chinese traditional medicine layer Top, uniform fold rosin hot melt adhesive Chinese traditional medicine layer, is cooled to solid-state, formed above rosin hot melt adhesive Chinese traditional medicine layer with a thickness of 7 ~ The crystallite wax layer of 9mm is to get wax therapy Chinese medicine wax stone.
Optionally, step 3)In further include being poured on step 2 again after the microwax for being melted into liquid is cooled to 75 ~ 80 DEG C) The top of middle rosin hot melt adhesive Chinese traditional medicine layer.Liquid microwax is avoided directly to make hot melt adhesive layer molten when contacting rosin hot melt adhesive Chinese traditional medicine layer Melt as liquid, it is ensured that hot melt adhesive has good viscosity, beeswax layer and crystallite wax layer is bonded, conducive to the molding of wax stone.
Above-mentioned wax therapy when in use, Chinese medicine wax stone tinfoil is wrapped up tightly, then wrap one layer of preservative film with Chinese medicine wax stone, It is put into the water-bath that temperature is 65 DEG C or so, takes out within 30 minutes or so, after cooling 3 ~ 5min, remove preservative film and tinfoil, it will Wax stone after heating water bath softening, which is covered on human body, needs the position of wax therapy, such as shoulder neck, waist, leg.
Solid beeswax density is small, light-weight, and section sand shape, flexibility is good, and being pinched with hand rubbing can soften;It is solid micro- Brilliant wax large viscosity has ductility, not fragile at low temperature.Beeswax is being kept the temperature due to microwax in terms of flexibility and plasticity Microwax is better than beeswax in terms of accumulation of heat.
The Moschus that the present invention uses is muscone.
Wax therapy of the present invention Chinese medicine wax stone, so that the used time is internal layer close to patient skin, it from inside to outside successively include beeswax Layer, rosin hot melt adhesive Chinese traditional medicine layer and crystallite wax layer, three-decker setting, have the advantage that:
First, beeswax layer skin-proximal when in use, beeswax flexibility is good, and plasticity is strong, wax stone can be made close to wax therapy Position, and avoid generating tight discomfort in cooling procedure.Add although existing in the prior art in wax therapy raw material Enter flexibility and plasticity that the ingredients such as microwax or mineral mud promote entire raw material, but which kind of there will be different flexible natures The mode that directly mixes of raw material, be to neutralize the flexibility of each raw material, so that the flexibility of obtained raw material is better than Traditional wax stone, flexibility and plasticity, which still cannot reach, is pinched with hand rubbing and can be softened possessed by simple beeswax Flexibility;
Second, although simple beeswax has good flexibility and plasticity, since its density is small, section gravel The texture characteristic of shape, heat storage capacity is poor, thus will not be simple in traditional wax stone select beeswax as raw material, it usually needs Other ingredients are mixed to improve the heat storage capacity of wax stone.By the cementation of hot melt adhesive in the present invention, crystallite wax layer is glued The outer layer in beeswax layer is tied, entire beeswax layer is covered, since the heat storage capacity of crystallite wax layer is better than beeswax layer, the microwax of outer layer Layer combines intermediate hot melt adhesive layer that can prevent distributing for internal layer beeswax layer heat, extends the soaking time of entire wax stone, is promoted The using effect of wax stone;
Third, intermediate rosin hot melt adhesive Chinese traditional medicine layer, rosin and traditional Chinese medicine powder are entrained in hot melt adhesive, the centre in wax stone Layer, can be avoided the forfeiture of the volatilization and drug effect of rosin and traditional Chinese medicine ingredients in placement process, and the present invention designs wax stone At three-decker, compared to traditional single layer wax stone structure, the thickness for the beeswax layer for directly contacting skin in the present invention is obviously reduced, Conducive in hot melt adhesive layer rosin and traditional Chinese medicine ingredients infiltrate through and beeswax layer and then be absorbed transdermally, infiltrate through the rosin energy of beeswax layer Enough further flexibilities and plasticity for improving beeswax layer, it is ensured that beeswax layer and skin are in close contact, and skin feel is avoided to arrive Tight feeling;
4th, each Chinese medicine material in wax stone of the present invention cooperates with compatibility, and by the heating power of wax stone, effective component can be quick The effect of go directly lesions position, plays dispelling wind and eliminating dampness, promoting qi circulation and relieving pain, dispersing swelling and dissipating binds altogether, aching and tired, the pain at the positions such as link shoulder neck waist-leg Bitterly, out of strength and joint and soft tissue injury, the symptoms such as ache caused by strain:Aconiti preparata,radix and wild aconite root are as monarch drug in a prescription, cold dispelling Damp dispelling and pain relieving, dragon's blood can the promoting flow of qi and blood circulation, promote blood circulation;It is aided with lopseed, the soft muscle dredging collateral of lycopodium calvatum;The root of Chinese clematis and gentianae macrophyllae are dispelled Wind, dissipating cold;Olibanum and myrrh compatibility, energy activating microcirculation and removing stasis medicinal, clearing and activating the channels and collaterals;Psoralea corylifolia, Semen Cuscutae, radix achyranthis bidentatae can nourishing liver and kidney, strengthening the bones and muscles, Sharp joint enhances help effect with cortex cinnamomi as adjutant;Moschus can eliminate dampness with aromatics, and priming object guides drugs to illness station, and can play its compared with The function of strong clearing and activating the channels and collaterals.
5th, wax stone of the present invention is neutrality with a thickness of 17 ~ 23mm, PH, and oil content is low(3%), hardness is moderate(Needle enters Spend 15mm), poor thermal conductivity, thermal capacity is big, and a large amount of heat is absorbed when melting, slowly releases heat when cooling, is dissipated Hot slow, soaking time is long, can effectively drive away the induced pain factor, diminish inflammation, and delays joint ageing speed, and QI invigorating righting reconciles Yin-yang, thoroughly in expression, the promoting flow of qi and blood circulation, to achieve the purpose that dispelling disease;
6th, further, the present invention in use azone, house oil and Marmot oil three's complex role bleeding agent, mutually it Between play synergistic function, promote traditional Chinese medicine ingredients and rosin to infiltrate through beeswax layer, and then enhance the saturating of traditional Chinese medicine ingredients and rosin Skin absorption promotes the drug therapy and health-care effect of wax stone.
The preparation method of wax therapy of the present invention Chinese medicine wax stone, it is easy to operate, it is easily controllable, it is suitable for industrial application.
Specific embodiment
The technical scheme of the invention is described in detail through specific implementation examples.
Embodiment 1
A kind of wax therapy Chinese medicine wax stone so that the used time close to patient skin be internal layer, from inside to outside successively include beeswax layer, Rosin hot melt adhesive Chinese traditional medicine layer and crystallite wax layer;Wherein rosin hot melt adhesive Chinese traditional medicine layer is prepared by following raw material in parts by weight: Hot-fusible pressure-sensitive adhesive 100g, traditional Chinese medicine powder 50g, rosin 5g, bleeding agent 1.5g;
With every gram of traditional Chinese medicine powder for an entirety, the traditional Chinese medicine powder is made of the raw material of following parts by weight:60 parts of aconiti preparata,radix, 60 parts of wild aconite root, 50 parts of the root of Chinese clematis, 50 parts of gentianae macrophyllae, 50 parts of lycopodium calvatum, 50 parts of lopseed, 50 parts of psoralea corylifolia, 50 parts of Semen Cuscutae, ox 50 parts of knee, 50 parts of cortex cinnamomi, 60 parts of olibanum, 60 parts of myrrh, 50 parts of dragon's blood, 10 parts of Moschus;
The beeswax layer with a thickness of 5mm, rosin hot melt adhesive Chinese traditional medicine layer with a thickness of 7mm, crystallite wax layer with a thickness of 8mm;
The bleeding agent is by azone, house oil and Marmot oil according to mass ratio 4:3:2 compositions.
The preparation method of the present embodiment wax therapy Chinese medicine wax stone, including following operating procedure:
1)Prepare beeswax layer:It takes 150g beeswax to pour into heating and melting in wax melter and the beeswax of liquid is poured into rule at liquid Lattice are in the pallet of 17*23*2cm, and cooled and solidified is at the beeswax layer with a thickness of 5mm;
2)Prepare rosin hot melt adhesive Chinese traditional medicine layer:It takes each Chinese medicine material to be ground into powder-mixed uniform, obtains traditional Chinese medicine powder;Take heat Melten gel and rosin are added heating melting in wax melter and traditional Chinese medicine powder then are added and bleeding agent is mixed evenly to semi-fluid condition In paste, paste is uniformly spread out in step 1)The top of the beeswax layer of preparation is formed in the top of beeswax layer with a thickness of 7mm Rosin hot melt adhesive Chinese traditional medicine layer;
3)Prepare crystallite wax layer:It takes 200g microwax that heating and melting in wax melter is added to fall after being cooled to 80 DEG C at liquid In step 2)The top of middle rosin hot melt adhesive Chinese traditional medicine layer, uniform fold rosin hot melt adhesive Chinese traditional medicine layer, is cooled to solid-state, in rosin heat The crystallite wax layer with a thickness of 8mm is formed above melten gel Chinese traditional medicine layer to get wax therapy Chinese medicine wax stone.
The present embodiment wax therapy when in use, Chinese medicine wax stone tinfoil is wrapped up tightly, then wrap one layer of guarantor with Chinese medicine wax stone Fresh film is put into the water-bath that temperature is 65 DEG C or so, is taken out within 30 minutes or so, after cooling 3 ~ 5min, removes preservative film and tin Paper, the wax stone after heating water bath is softened, which is covered on human body, needs the position of wax therapy, such as shoulder neck, waist, leg.
Embodiment 2
A kind of wax therapy Chinese medicine wax stone so that the used time close to patient skin be internal layer, from inside to outside successively include beeswax layer, Rosin hot melt adhesive Chinese traditional medicine layer and crystallite wax layer;Wherein rosin hot melt adhesive Chinese traditional medicine layer is prepared by following raw material in parts by weight: Hot-fusible pressure-sensitive adhesive 90g, traditional Chinese medicine powder 45g, rosin 4g, bleeding agent 1g;
With every gram of traditional Chinese medicine powder for an entirety, the traditional Chinese medicine powder is made of the raw material of following parts by weight:55 parts of aconiti preparata,radix, 55 parts of wild aconite root, 45 parts of the root of Chinese clematis, 45 parts of gentianae macrophyllae, 45 parts of lycopodium calvatum, 45 parts of lopseed, 45 parts of psoralea corylifolia, 45 parts of Semen Cuscutae, ox 45 parts of knee, 45 parts of cortex cinnamomi, 55 parts of olibanum, 55 parts of myrrh, 45 parts of dragon's blood, 8 parts of Moschus;
The beeswax layer with a thickness of 4mm, rosin hot melt adhesive Chinese traditional medicine layer with a thickness of 6mm, crystallite wax layer with a thickness of 7mm;
The bleeding agent is by azone, house oil and Marmot oil according to mass ratio 3:2:1 composition.
The preparation method of the present embodiment wax therapy Chinese medicine wax stone, including following operating procedure:
1)Prepare beeswax layer:It takes 140g beeswax to pour into heating and melting in wax melter and the beeswax of liquid is poured into rule at liquid Lattice are in the pallet of 17*23*2cm, and cooled and solidified is at the beeswax layer with a thickness of 4mm;
2)Prepare rosin hot melt adhesive Chinese traditional medicine layer:It takes each Chinese medicine material to be ground into powder-mixed uniform, obtains traditional Chinese medicine powder;Take heat Melten gel and rosin are added heating melting in wax melter and traditional Chinese medicine powder then are added and bleeding agent is mixed evenly to semi-fluid condition In paste, paste is uniformly spread out in step 1)The top of the beeswax layer of preparation is formed in the top of beeswax layer with a thickness of 6mm Rosin hot melt adhesive Chinese traditional medicine layer;
3)Prepare crystallite wax layer:It takes 190g microwax that heating and melting in wax melter is added to fall after being cooled to 75 DEG C at liquid In step 2)The top of middle rosin hot melt adhesive Chinese traditional medicine layer, uniform fold rosin hot melt adhesive Chinese traditional medicine layer, is cooled to solid-state, in rosin heat The crystallite wax layer with a thickness of 7mm is formed above melten gel Chinese traditional medicine layer to get wax therapy Chinese medicine wax stone.
The application method of the present embodiment wax therapy Chinese medicine wax stone:Chinese medicine wax stone tinfoil is wrapped up tightly, then wraps one layer Preservative film, being put into temperature is to take out within 30 minutes or so in 65 DEG C or so of water-bath, after cooling 3 ~ 5min, removal preservative film and Tinfoil, the wax stone after heating water bath is softened, which is covered on human body, needs the position of wax therapy, such as shoulder neck, waist, leg.
Embodiment 3
A kind of wax therapy Chinese medicine wax stone so that the used time close to patient skin be internal layer, from inside to outside successively include beeswax layer, Rosin hot melt adhesive Chinese traditional medicine layer and crystallite wax layer;Wherein rosin hot melt adhesive Chinese traditional medicine layer is prepared by following raw material in parts by weight: Hot-fusible pressure-sensitive adhesive 110g, traditional Chinese medicine powder 55g, rosin 6g, bleeding agent 2g;
With every part of traditional Chinese medicine powder for an entirety, the traditional Chinese medicine powder is made of the raw material of following parts by weight:65 parts of aconiti preparata,radix, 65 parts of wild aconite root, 55 parts of the root of Chinese clematis, 55 parts of gentianae macrophyllae, 55 parts of lycopodium calvatum, 55 parts of lopseed, 55 parts of psoralea corylifolia, 55 parts of Semen Cuscutae, ox 55 parts of knee, 55 parts of cortex cinnamomi, 65 parts of olibanum, 65 parts of myrrh, 55 parts of dragon's blood, 12 parts of Moschus;
The beeswax layer with a thickness of 6mm, rosin hot melt adhesive Chinese traditional medicine layer with a thickness of 8mm, crystallite wax layer with a thickness of 9mm;
The bleeding agent is by azone, house oil and Marmot oil according to mass ratio 5:2.5:1.5 composition.
The preparation method of the present embodiment wax therapy Chinese medicine wax stone, including following operating procedure:
1)Prepare beeswax layer:It takes 160g beeswax to pour into heating and melting in wax melter and the beeswax of liquid is poured into rule at liquid Lattice are in the pallet of 17*23*2.5cm, and cooled and solidified is at the beeswax layer with a thickness of 6mm;
2)Prepare rosin hot melt adhesive Chinese traditional medicine layer:It takes each Chinese medicine material to be ground into powder-mixed uniform, obtains traditional Chinese medicine powder;Take heat Melten gel and rosin are added heating melting in wax melter and traditional Chinese medicine powder then are added and bleeding agent is mixed evenly to semi-fluid condition In paste, paste is uniformly spread out in step 1)The top of the beeswax layer of preparation is formed in the top of beeswax layer with a thickness of 8mm Rosin hot melt adhesive Chinese traditional medicine layer;
3)Prepare crystallite wax layer:It takes 210g microwax that heating and melting in wax melter is added to fall after being cooled to 78 DEG C at liquid In step 2)The top of middle rosin hot melt adhesive Chinese traditional medicine layer, uniform fold rosin hot melt adhesive Chinese traditional medicine layer, is cooled to solid-state, in rosin heat The crystallite wax layer with a thickness of 9mm is formed above melten gel Chinese traditional medicine layer to get wax therapy Chinese medicine wax stone.
The present embodiment wax therapy when in use, Chinese medicine wax stone tinfoil is wrapped up tightly, then wrap one layer of guarantor with Chinese medicine wax stone Fresh film is put into the water-bath that temperature is 65 DEG C or so, is taken out within 30 minutes or so, after cooling 3 ~ 5min, removes preservative film and tin Paper, the wax stone after heating water bath is softened, which is covered on human body, needs the position of wax therapy, such as shoulder neck, waist, leg.
Comparative example 1
This comparative example wax therapy Chinese medicine wax stone, eliminates the need for hot melt adhesive in preparation process, other raw materials and consumptions and implements Example 1 is identical, unlike the first embodiment, during the preparation process by beeswax and microwax mixed melting at liquid after, be added it is other Raw material is uniformly mixed, and is cooled to solid-state, the wax stone of single layer structure is made.
Comparative example 2
This comparative example wax therapy Chinese medicine wax stone, it is unlike the first embodiment, other using simple azone as bleeding agent With embodiment 1.
Comparative example 3
This comparative example wax therapy Chinese medicine wax stone, it is unlike the first embodiment, other using simple house oil as bleeding agent With embodiment 1.
Comparative example 4
This comparative example wax therapy Chinese medicine wax stone, unlike the first embodiment, using simple Marmot oil as bleeding agent, It is the same as embodiment 1.
Test example 1
Test method:50 30 ~ 40 years old volunteers are chosen, are arbitrarily divided into two groups, every group of 25 people, respectively according to embodiment The application method of wax stone described in 1 carries out wax therapy to each volunteer, wherein one group of volunteer applies wax stone prepared by embodiment 1, Another set volunteer applies wax stone prepared by comparative example 1, counts volunteer during the soaking time and wax therapy of every group of wax stone Skin feel, the results showed that, wax stone prepared by embodiment 1 is able to maintain wax stone with lasting warm in 40min ~ 50min Sense, and it is able to maintain good flexibility, it is in close contact with skin, no tight feeling;Wax stone prepared by comparative example 1 is in 20min It is interior can wax stone be able to maintain lasting warmth sensation and flexibility, there is hardening phenomenon in wax stone after 20min, and patient can experience tightly Taut sense, the practicability is poor.
Test example 2
Test method:It is through medium, using Franz diffusion cell method, with rosin in wax stone in piggy skin of abdomen The principle active component alkaloid of medicine is index, the Drug Percutaneous Absorption of wax stone prepared by measurement embodiment 1, comparative example 1 ~ 4 Can, wherein the wax stone for carrying out the test of Franz diffusion cell is all made of wax stone application method described in embodiment 1 and is handled, biology The content of alkali and rosin is detected using high performance liquid chromatography, and the content size of the biology and rosin that detect is embodiment 1 3 > comparative example of > comparative example, 4 > comparative example 2 > comparative example 1, effective component in the wax stone of the result surface embodiment 1 preparation Transdermal absorption performance is best, illustrates there is the percutaneous absorbability that collaboration improves infiltration and drug between azone, house oil and Marmot oil Can synergistic effect, while the wax stone of three-decker that uses of the present invention further improves the infiltration and Transdermal absorption of drug Performance improves the medicinal health-care and therapeutic effect of wax stone.

Claims (7)

1. a kind of wax therapy Chinese medicine wax stone, which is characterized in that so that the used time is internal layer close to patient skin, successively wrap from inside to outside Include beeswax layer, rosin hot melt adhesive Chinese traditional medicine layer and crystallite wax layer;Wherein rosin hot melt adhesive Chinese traditional medicine layer by following parts by weight raw material It is prepared:90 ~ 110 parts of hot melt adhesive, 45 ~ 55 parts of traditional Chinese medicine powder, 4 ~ 6 parts of rosin, 1 ~ 2 part of bleeding agent;
With every part of traditional Chinese medicine powder for an entirety, the traditional Chinese medicine powder is made of the raw material of following parts by weight:55 ~ 65 parts of aconiti preparata,radix, 55 ~ 65 parts of wild aconite root, 45 ~ 55 parts of the root of Chinese clematis, 45 ~ 55 parts of gentianae macrophyllae, 45 ~ 55 parts of lycopodium calvatum, 45 ~ 55 parts of lopseed, psoralea corylifolia 45 ~ 55 parts, 45 ~ 55 parts of Semen Cuscutae, 45 ~ 55 parts of radix achyranthis bidentatae, 45 ~ 55 parts of cortex cinnamomi, 55 ~ 65 parts of olibanum, 55 ~ 65 parts of myrrh, dragon's blood 45 ~ 55 Part, 8 ~ 12 parts of Moschus;
The beeswax layer with a thickness of 4 ~ 6mm, rosin hot melt adhesive Chinese traditional medicine layer with a thickness of 6 ~ 8mm, crystallite wax layer with a thickness of 7 ~ 9mm。
2. wax therapy as described in claim 1 Chinese medicine wax stone, which is characterized in that the bleeding agent is by azone, house oil and marmot Oil is according to mass ratio 3 ~ 5:2~3:1 ~ 2 composition.
3. wax therapy as claimed in claim 2 Chinese medicine wax stone, which is characterized in that the bleeding agent is by azone, house oil and marmot Oil is according to mass ratio 4:3:2 compositions.
4. such as claim 1 ~ 3 described in any item wax therapys Chinese medicine wax stone, which is characterized in that the hot melt adhesive is melt pressure sensitive One of glue, polyamide hot, EVA hot-melt adhesive or any combination.
5. such as claim 1 ~ 3 described in any item wax therapys Chinese medicine wax stone, which is characterized in that rosin hot melt adhesive Chinese traditional medicine layer by with The raw material of lower parts by weight is prepared:100 parts of hot melt adhesive, 50 parts of traditional Chinese medicine powder, 5 parts of rosin, 1.5 parts of bleeding agent;
With every part of traditional Chinese medicine powder for an entirety, the traditional Chinese medicine powder is made of the raw material of following parts by weight:60 parts of aconiti preparata,radix, system grass Black 60 parts, 50 parts of the root of Chinese clematis, 50 parts of gentianae macrophyllae, 50 parts of lycopodium calvatum, 50 parts of lopseed, 50 parts of psoralea corylifolia, 50 parts of Semen Cuscutae, radix achyranthis bidentatae 50 Part, 50 parts of cortex cinnamomi, 60 parts of olibanum, 60 parts of myrrh, 50 parts of dragon's blood, 10 parts of Moschus;
The beeswax layer with a thickness of 5mm, rosin hot melt adhesive Chinese traditional medicine layer with a thickness of 7mm, crystallite wax layer with a thickness of 8mm.
6. a kind of preparation method of wax therapy as described in claim 1 Chinese medicine wax stone, which is characterized in that walked including following operation Suddenly:
1)Prepare beeswax layer:It takes beeswax heating and melting at liquid, pours into wax stone molding die, formed after liquid beeswax is cooling thick Degree is the beeswax layer of 4 ~ 6mm;
2)Prepare rosin hot melt adhesive Chinese traditional medicine layer:It takes each Chinese medicine material to be ground into powder-mixed uniform, obtains traditional Chinese medicine powder;Take hot melt adhesive Semi-fluid condition is melted to rosin Hybrid Heating, traditional Chinese medicine powder is then added and bleeding agent is mixed evenly in paste, it will Paste is uniformly spread out in step 1)The top of the beeswax layer of preparation forms the rosin heat with a thickness of 6 ~ 8mm in the top of beeswax layer Melten gel Chinese traditional medicine layer;
3)Prepare crystallite wax layer:It takes microwax heating and melting at liquid, is poured on step 2)The top of middle rosin hot melt adhesive Chinese traditional medicine layer, Uniform fold rosin hot melt adhesive Chinese traditional medicine layer, is cooled to solid-state, is formed above rosin hot melt adhesive Chinese traditional medicine layer with a thickness of the micro- of 7 ~ 9mm Brilliant wax layer is to get wax therapy Chinese medicine wax stone.
7. the wax therapy as claimed in claim 6 preparation method of Chinese medicine wax stone, which is characterized in that step 3)In further include that will melt The microwax of chemical conversion liquid is poured on step 2 after being cooled to 75 ~ 80 DEG C again)The top of middle rosin hot melt adhesive Chinese traditional medicine layer.
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