CN105748745A - Biological wax for treating femoral head necrosis and preparing method - Google Patents
Biological wax for treating femoral head necrosis and preparing method Download PDFInfo
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- CN105748745A CN105748745A CN201610277776.7A CN201610277776A CN105748745A CN 105748745 A CN105748745 A CN 105748745A CN 201610277776 A CN201610277776 A CN 201610277776A CN 105748745 A CN105748745 A CN 105748745A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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Abstract
The invention discloses a biological wax for treating femoral head necrosis and a preparing method.The biological wax is prepared from bee wax, artemisia argyl oil and Chinese herb extract.The Chinese herb extract is prepared from narrowleaf rockvine roots or herb, aleppo avens herb, herb of cupleaf passionflower and corymb polycarpaea herb in proportional compatibility with an alcohol extraction method.Clinical tests show that the treatment effect on the femoral head is good.
Description
Technical field
The invention belongs to the formulation art of wax therapy in traditional medical, particularly relate to a kind of biowax treating femur head necrosis and preparation method.
Background technology
Paraffin is applied to rehabilitation the history in a lot of year, and the curative effect special because of it is used till today always.Mostly all still use common wax or the wax through simple mediation at present, its function is more single, offer limited effectiveness, can not meet the development of society, the needs of life gradually.For this, we are through practical experience for many years, while not affecting the functions such as pliability, tack, plasticity, heat build-up, Chinese mugwort oil, Chinese herbal medicine extract are fused to inside paraffin, after making physical therapy wax work, its thermal capacity, heat conductivity, the thermal protection time etc. does not have much changes, but at blood circulation promoting, diminish inflammation, ease pain, improve metabolism, eliminate the aspect such as swelling, softening cicatrix, its raising evident in efficacy, especially for clinical treatment femur head necrosis, has good curative effect.
Summary of the invention
It is an object of the invention to provide a kind of biowax treating femur head necrosis.
The preparation method that it is a further object of the present invention to provide the biowax for the treatment of femur head necrosis.
It is an object of the invention to be achieved through the following technical solutions, the biowax of this treatment femur head necrosis is made up of the raw material of following weight: Cera Flava 400-500g, Chinese mugwort oil 20-30g, Chinese herbal medicine extract 10-20g.
Preferred: Cera Flava 450g, Chinese mugwort oil 25g, Chinese herbal medicine extract 15g.
Effect of Cera Flava: Chinese medicine beeswax has effect of removing toxic substances, granulation promoting, analgesic therapy, for oral administration and external application can cure mainly have to go to the toilet pained, dysentery pus and blood, incessant chronic diarrhea, vaginal bleeding due to excessive movement of fetus, carbuncle sore inside fire attack, burst for a long time and do not hold back, burn due to hot liquid or fire etc..
Effect of Chinese mugwort oil: rheumatic bones and muscles pain, congestive edema joint numbness, traumatic injury are bent wound, antiinflammatory stop trace itch, the acid of lumbar vertebra nape, tripe abdomen breast nebula pain, wind syndrome of head urgency twinge etc., all have significant curative effect.
Described Chinese herbal medicine extract is by Chinese herbal medicine: Radix seu Herba Tetrastigmatis Hypoglauci, Radix seu Herba Gei aleppici, Herba Passiflorae Cupiformis, Herba Polycarpaeae Corymbosae, weight ratio by 2: 2: 3: 1 is pulverized after mixing, cross 100 mesh sieves, add the ethanol water that appropriate concentration is 90%, soak 48 hours, then the solidliquid mixture ultrasonic assistant that will process extracts, ultrasonic extraction condition: ultrasonic temperature is 60 DEG C, supersonic frequency is 30kHz, the supersound extraction time is 40 minutes；Then by solidliquid mixture sucking filtration under 30kPa vacuum condition, take filtrate and reduce pressure under 20kPa vacuum, 50 DEG C of conditions distillation, reclaim ethanol, obtain the mixture containing extract component and water；Then namely its concentration and evaporation is obtained this Chinese herbal medicine extract.
Fang Zhong: Radix seu Herba Tetrastigmatis Hypoglauci synthetism granulation promoting, expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral, reducing swelling and alleviating pain；Radix seu Herba Gei aleppici expelling wind and removing dampness, promoting blood circulation and detumescence, anti-inflammatory analgetic, relieving convulsion；Herba Passiflorae Cupiformis detoxifies, stops blooding, relieves dizziness, high fever, infantile convulsions, epilepsy, etc., eases pain, tranquilizing by nourishing the heart, dehumidifying are active；Herba Polycarpaeae Corymbosae heat-clearing and toxic substances removing；Herba seu Radix Nothopanacis delavayi heat-clearing and toxic substances removing, regulating QI to relieve pain.The preparation method of a kind of biowax treating femur head necrosis is as follows:
1. the raw material for standby of respective components weight is weighed.
2. desired amount of Cera Flava is put into aluminum pot, be placed on slow fire and heat.
3., after treating that Cera Flava is completely melt, add desired amount of Chinese mugwort oil, Chinese herbal medicine extract, heat while stirring, merge completely to material.
Beneficial effects of the present invention: owing to the present invention adopts the Cera Flava of high-quality, Chinese mugwort oil, Chinese herbal medicine extract, improve drug effect, change the permeability of wax, makes diathermanous, infiltration usefulness raising, more remarkable treatment effect.
The sick row of typical case
Liu, man, within 49 years old, in row double hip joint MRI inspection on April 26th, 2013, diagnose as bilateral femoral head bland necrosis.The patient's condition: double hip joint limitation of activity, anteflexion L90 °, R80 °, after stretch L4 °, R1 °, interior receive L15 °, R5 °, abduction L30 °, R10 °, outward turning L30 °, R10 °, inward turning L20 °, R5 °.Total range of motion L189 °, extensive tenderness around R101 ° of right hip joint, outer under groin midpoint, left side, greater trochanter tenderness, bilateral " 4 " word is tested, and right lateral thigh rolling test, greater trochanter percussion test are all positive.Atrophy that right quadriceps femoris is slight.Bilateral femoral head MR is on average shown in that bilateral femoral head becomes flat (attaching most importance to right side), the visible long T1 of lamellar in bilateral femoral head, long T2 abnormal signal stove, pressure fat is as in high signal, double hip joint gap turn narrow, right hips intracavity is shown in a large amount of long T1, long T2 liquid signal.X-ray film shows: right lateral thigh bone profile is irregular, and right lateral thigh bone becomes flat, and bilateral femoral head bone trabecula is disorderly, and right lateral thigh bone is dispersed in cystis degeneration district.Difficulty in walking, after restraint, pain can be stood, and external application biowax of the present invention is pain disappearance after three months, range of motion is obviously improved, anteflexion L110 °, R100 °, after stretch L5 °, R4 °, interior receive L30 °, R20 °, abduction L45 °, R40 °, outward turning L50 °, R40 °, inward turning L40 °, R30 °.Total range of motion L275 °, follows up a case by regular visits to so far by R234 °, has abandoned in March, 2014 and has turned, and existing life, work are all without obvious adverse reaction.
Zhu, man 61 years old, workman.Autumn in May, 2012 goes to a doctor, and (ethanol rheumatism combination type) is worked as lumbar intervertebral disc and treated two months in somewhere, aggravation.Leaning on crutches when coming, both legs are had difficulty in taking a step.X sheet display bilateral femoral head all disappears, and with serious colitis, worn to a shadow, both legs are pain all night, after biowax external application for curing of the present invention three months, can completely take off and turn walking.And water can be carried, embrace bavin, sweep the floor, cook.
Detailed description of the invention
This biowax is made up of the raw material of following weight: Cera Flava 450g, Chinese mugwort oil 25g, Chinese herbal medicine extract 15g, Chinese herbal medicine extract is by Chinese herbal medicine: Radix seu Herba Tetrastigmatis Hypoglauci, Radix seu Herba Gei aleppici, Herba Passiflorae Cupiformis, Herba Polycarpaeae Corymbosae, weight ratio by 2: 2: 3: 1 is pulverized after mixing, cross 100 mesh sieves, add the ethanol water that appropriate concentration is 90%, soak 48 hours, then the solidliquid mixture ultrasonic assistant that will process extracts, ultrasonic extraction condition: ultrasonic temperature is 60 DEG C, supersonic frequency is 30kHz, the supersound extraction time is 40 minutes；Then by solidliquid mixture sucking filtration under 30kPa vacuum condition, take filtrate and reduce pressure under 20kPa vacuum, 50 DEG C of conditions distillation, reclaim ethanol, obtain the mixture containing extract component and water；Then namely its concentration and evaporation is obtained this Chinese herbal medicine extract.
The preparation method of a kind of biowax treating femur head necrosis is as follows:
1. the raw material for standby of respective components weight is weighed.
2. desired amount of Cera Flava is put into aluminum pot, be placed on slow fire and heat.
3., after treating that Cera Flava is completely melt, add desired amount of Chinese mugwort oil, Chinese herbal medicine extract, heat while stirring, merge completely to material.
Claims (3)
1. the biowax treating femur head necrosis, it is characterised in that this biowax is made up of the raw material of following weight: Cera Flava 400-500g, Chinese mugwort oil 20-30g, Chinese herbal medicine extract 10-20g.
2. a kind of biowax treating femur head necrosis as claimed in claim 1, it is characterised in that this biowax is made up of the raw material of following weight: Cera Flava 450g, Chinese mugwort oil 25g, Chinese herbal medicine extract 15g.
3. a kind of biowax treating femur head necrosis as claimed in claim 1 or 2, it is characterized in that described Chinese herbal medicine extract is by Chinese herbal medicine: Radix seu Herba Tetrastigmatis Hypoglauci, Radix seu Herba Gei aleppici, Herba Passiflorae Cupiformis, Herba Polycarpaeae Corymbosae, weight ratio by 2: 2: 3: 1 is pulverized after mixing, cross 100 mesh sieves, add the ethanol water that appropriate concentration is 90%, soak 48 hours, then the solidliquid mixture ultrasonic assistant processed is extracted, ultrasonic extraction condition, ultrasonic temperature is 60 DEG C, supersonic frequency is 30kHz, the supersound extraction time is 40 minutes, then by solidliquid mixture sucking filtration under 30kPa vacuum condition, take filtrate in 20kPa vacuum, decompression distillation under 50 DEG C of conditions, reclaim ethanol, obtain the mixture containing extract component and water, then namely its concentration and evaporation is obtained this Chinese herbal medicine extract.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610277776.7A CN105748745A (en) | 2016-04-20 | 2016-04-20 | Biological wax for treating femoral head necrosis and preparing method |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610277776.7A CN105748745A (en) | 2016-04-20 | 2016-04-20 | Biological wax for treating femoral head necrosis and preparing method |
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| CN105748745A true CN105748745A (en) | 2016-07-13 |
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| CN201610277776.7A Pending CN105748745A (en) | 2016-04-20 | 2016-04-20 | Biological wax for treating femoral head necrosis and preparing method |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106726101A (en) * | 2017-01-11 | 2017-05-31 | 郑州紫德堂生物科技有限公司 | A kind of wax therapy Chinese medicine wax stone and preparation method thereof |
| CN106798608A (en) * | 2017-01-23 | 2017-06-06 | 罗述旭 | A kind of wax therapy wax mud and preparation method thereof |
| CN111603301A (en) * | 2020-02-27 | 2020-09-01 | 郑州爱博尔医疗设备有限公司 | Production formula of hot compress wax mud block |
-
2016
- 2016-04-20 CN CN201610277776.7A patent/CN105748745A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106726101A (en) * | 2017-01-11 | 2017-05-31 | 郑州紫德堂生物科技有限公司 | A kind of wax therapy Chinese medicine wax stone and preparation method thereof |
| CN106726101B (en) * | 2017-01-11 | 2018-11-23 | 郑州紫德堂生物科技有限公司 | A kind of wax therapy Chinese medicine wax stone and preparation method thereof |
| CN106798608A (en) * | 2017-01-23 | 2017-06-06 | 罗述旭 | A kind of wax therapy wax mud and preparation method thereof |
| CN106798608B (en) * | 2017-01-23 | 2018-10-23 | 罗述旭 | A kind of wax therapy wax mud and preparation method thereof |
| CN111603301A (en) * | 2020-02-27 | 2020-09-01 | 郑州爱博尔医疗设备有限公司 | Production formula of hot compress wax mud block |
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Application publication date: 20160713 |
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| WD01 | Invention patent application deemed withdrawn after publication |