CN106725695A - A kind of blood vessel plugging device - Google Patents
A kind of blood vessel plugging device Download PDFInfo
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- CN106725695A CN106725695A CN201710064609.9A CN201710064609A CN106725695A CN 106725695 A CN106725695 A CN 106725695A CN 201710064609 A CN201710064609 A CN 201710064609A CN 106725695 A CN106725695 A CN 106725695A
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- hemostasis
- parts
- sponge cover
- blood vessel
- plugging device
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12027—Type of occlusion
- A61B17/12031—Type of occlusion complete occlusion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
- A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/12159—Solid plugs; being solid before insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00004—(bio)absorbable, (bio)resorbable, resorptive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B2017/12004—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord for haemostasis, for prevention of bleeding
Abstract
The invention discloses a kind of blood vessel plugging device, including outer barrel, push rod, the biodegradable drawstring of energy, sponge cover and hemostasis spheroid, the push rod is slidably matched in outer barrel, drawstring one end is connected after sequentially passing through push rod and sponge cover with hemostasis spheroid, sponge cover is movably arranged in outer barrel, and hemostatic ball physical efficiency is fitted into sponge cover, and sponge cover is strutted, sponge cover inwall is provided with the stopper slot for spacing hemostasis spheroid, and the sponge cover and hemostasis spherome surface are coated with hemostasis and anti-inflammation layer.The present invention is simple to operate, and hemostasis is fast, small to blood vessel wound pressure, it is to avoid wound inflammation and degradable, and residue will not be left in patient's body.
Description
Technical field
The invention belongs to technical field of medical instruments, more particularly to a kind of blood vessel plugging device.
Background technology
At present, when PCI angiocardiopathy is carried out, lead sheath is first often inserted into artery through epidermis, then by lead sheath
Insertion access device, needs to block wound after the completion of operation.Clinically have two using more plugging device at present
Kind：One kind is artery stitch device, but its complex operation, patient pain can be caused in suture, and suture is not tight, and it is used
Wire non-degradable can be trapped in human body；Another kind is sponge type plugging device, and its operation is also more complicated, and to wound
Mouth pressure is larger, the easy inflammation of wound.
Therefore, how to solve the defect of above-mentioned prior art presence becomes the direction of art personnel effort.
The content of the invention
It is an object of the invention to provide a kind of blood vessel plugging device, can be fully solved above-mentioned the deficiencies in the prior art it
Place.
The purpose of the present invention is realized by following technical proposals：
A kind of blood vessel plugging device, including outer barrel, push rod, the biodegradable drawstring of energy, sponge cover and hemostasis spheroid, it is described
Push rod is slidably matched in outer barrel, and drawstring one end is connected after sequentially passing through push rod and sponge cover with hemostasis spheroid, the activity of sponge cover
It is arranged in outer barrel, hemostatic ball physical efficiency is fitted into sponge cover, and sponge cover is strutted, sponge cover inwall is provided with for spacing
The stopper slot of hemostasis spheroid, the sponge cover and hemostasis spherome surface are coated with hemostasis and anti-inflammation layer.
Preferably, the sponge cover is truncated cone-shaped, its top is provided with the groove matched with push rod bottom.
Preferably, the sponge cover is biodegradable sponge.
Preferably, the hemostasis spheroid is made of Biodegradable material.
In above-mentioned blood vessel plugging device, the hemostasis and anti-inflammation layer is calculated in parts by weight, including following components：Giant knotweed 20~
45 parts, 20~28 parts of gambir, 5~6 parts of red sandalwood, 5~8 parts of silk cocoon, 10~15 parts of Radix Isatidis, 10~15 parts of luffa, ramie
12~28 parts of root, 5~10 parts of rhododendron micranthum, 5~8 parts of Radix Glycyrrhizae, 3~5 parts of oblongleaf garcinia seed oil, 0.18~0.2 part of emulsifying agent, surface-active
0.04~0.05 part of agent.
A kind of preparation method of hemostasis and anti-inflammation layer for above-mentioned blood vessel plugging device, comprises the following steps：
(1) extracted by the way of alcohol extraction after giant knotweed, silk cocoon, Radix Isatidis, luffa, radix boehmeriae and Radix Glycyrrhizae are crushed respectively
It is 2~3 times, 2~3 days every time, merging filtrate after the leaching liquor filtering of each time is standby；
(2) red sandalwood is processed into bits, using soaking in Chinese liquor, leaches aubergine liquid, then uses charcoal absorption discoloration, must leach
Liquid is standby；
(3) gambir dry extract is suspended with 1.5 times of warm water of weight, obtains suspension standby；
(4) rhododendron micranthum is decocted and extracted, and filtering obtains filtrate, is concentrated under reduced pressure into the medicinal extract that water content is 35~38%, uses warm water
It is suspended, obtains suspension standby；
(5) step (3) and suspension obtained in step (4) are mixed, is extracted with chloroform, obtain extract standby；
(6) by filtrate, leachate, extract and wood obtained in step (5) obtained in step (2) obtained in step (1)
Bamboo oil mixing is stirred, and emulsifying agent and surfactant are added while stirring, forms dispersed emulsion, i.e.,
Obtain Hemostatic Oral Liquid；
(7) Hemostatic Oral Liquid obtained by step (6) is coated uniformly on sponge cover and hemostasis spherome surface forms hemostasis and anti-inflammation layer.
Further, the wine degree of white wine is arranged on 40~60% (V/V) in the step (2).
Further, the water temperature of warm water is 50~55 DEG C in the step (3) and (4).
Medicinal material of the present invention, wherein：
Giant knotweed：It is clearing heat and detoxicating with removing dampness through diuresis and removing jaundice, blood stasis removing analgesic, relieving cough and reducing sputum effect.
Gambir：Its bitter, puckery, cool in nature, tannin containing volume, can make astringent, and catechotannin contained therein can strengthen
Capillary resistance；Hygroscopic sore, analgesic therapy of stopping blooding, clearing heat and eliminating phlegm, main sore burst for a long time and does not holds back, wet sore flowing water, noma, aphtha,
Spitting of blood, is spitted blood, and hematuria is had blood in stool, metrorrhagia, traumatism and bleeding, hemorrhoid carbuncle swells.
Red sandalwood：It is salty, put down, nontoxic, detumescence, hemostasis, analgesic therapy.Control pyogenic infections, metal-inflicted wound bleeding；《Detailed outline》：" Asiatic sweet leaf pungent-warm, qi leel
Medicine, therefore can manage and defend gas and adjust spleen and lung, sharp chest diaphragm.Red sandalwood is salty-cold, the medicine of blood system, thus can and ying-qi and poison of subsiding a swelling, control gold
Sore.”《Bencao Jingshu》：" purple true wingceltis, the vicious wind toxin of master.All malicious Bi Yinre and send out, heat very then gives birth to wind, and ying blood is injured, and poison is raw
Here.This medicine is salty to enter blood, and trembling with fear can be then malicious to disappear certainly except heat.Great scape with deposit sore, hemostasis and pain-relieving person, also take this meaning ear.Preferably with
Kind drop smells good and is all superfine end, and deposit sore is good ".
Silk cocoon：It is sweet, temperature, nontoxic, hemostatic.
Radix Isatidis：It is clearing heat and detoxicating, cool blood, relieving sore-throat.
Luffa：Have clearing and activating the channels and collaterals, effect of removing toxicity for detumescence.
Radix boehmeriae：With heat-clearing, hemostasis, removing toxic substances, the stasis of blood is dissipated, to erysipelas, carbuncle swells, traumatic injury, the effects such as snake bite and insect sting.
Rhododendron micranthum：Wind-dispelling, dredging collateral, hemostasis.
Radix Glycyrrhizae：Clearing heat and detoxicating, expelling phlegm and arresting coughing, gastral cavity abdomen etc. are cured mainly, there is anti-inflammatory, anti-allergic effects.
Oblongleaf garcinia seed oil：With removing toxic substances, anti-inflammatory analgetic, effect of myogenic is restrained.
Emulsifying agent uses Carbomer.Surfactant uses the mixture of ethanolamine salt and secondary alcohol APEO, both
According to quality proportioning 2:1 mixing.Ethanolamine salt is cationic surfactant, its good water solubility, not only acidproof but also alkaline-resisting and have
Bactericidal action；Secondary alcohol APEO is nonionic surfactant, and its cold washing performance is equal with solubilising, dispersion, wetability
Preferably, the excitant to skin is very low；Because cationic surfactant is soft, sterilized, antistatic property is excellent, therefore by sun
Ionic surface active agent and nonionic surfactant coordinate can be obtained plus good effect.
Compared with prior art, the beneficial effects of the present invention are：Simple to operate, hemostasis is fast, small to blood vessel wound pressure,
Wound inflammation is avoided, and it is degradable, residue will not be left in patient's body.
Brief description of the drawings
Fig. 1 is structural representation of the invention；
Fig. 2 is the cross-sectional view of sponge cover in Fig. 1；
Fig. 3 is use state figure of the invention.
Specific embodiment
With reference to specific embodiments and the drawings, the present invention is further illustrated.
As depicted in figs. 1 and 2, a kind of blood vessel plugging device, including outer barrel 1, push rod 2, the biodegradable drawstring 3 of energy, sea
Silk floss cover 4 and hemostasis spheroid 5.The outer barrel 1 is the cylindrical tube shape matched with lead sheath.The push rod 2 is slidably fitted in outer barrel 1,
Can be in outer barrel 1 slidably.The one end of drawstring 3 is connected after sequentially passing through push rod 2 and sponge cover 4 with hemostasis spheroid 5, sponge cover 4
It is movably arranged in outer barrel 1, hemostasis spheroid 5 can be fitted into sponge cover 4, and sponge cover 4 is strutted, and the inwall of sponge cover 4 sets
There is the stopper slot 6 for spacing hemostasis spheroid 5.
The sponge cover 4 is truncated cone-shaped, and its top is provided with the groove 7 matched with the bottom of push rod 2.The groove 7 is inverted cone
Shape or reverse frustoconic, the preferred reverse frustoconic of the present embodiment, the bottom of push rod 2 match with the groove 7.This structure can realize push rod
Being automatically positioned between 2 and sponge cover 4, and coordinate tight, it is to avoid sponge cover 4 misplaces.
The sponge cover 4 uses biodegradable sponge.The hemostasis spheroid 5 is made of Biodegradable material.
Therefore, residue will not be left in human body after blood vessel wound healing.
Referring to Fig. 3, when in use, during outer barrel 1 inserted into the lead sheath having been placed at the wound of blood vessel 8, by push rod 2 by sponge
In cover 4 and the hemostasis push-in blood vessel 8 of spheroid 5, drawstring 3 is then pulled out, hemostasis spheroid 5 drives sponge cover 4 to move at wound,
Under the collective effect of push rod 2 and drawstring 3, hemostasis spheroid 5 is clamp-oned and outwards struts sponge cover 4 in sponge cover 4, while hemostatic ball
Body 5 is limited groove 6 and is fixed in sponge cover 4, it is to avoid it is skidded off.Then outer barrel 1 and push rod 2 are extracted out from lead sheath.Finally, together
When be pulled outwardly drawstring 3 and lead sheath so that sponge cover 4 and hemostasis spheroid 5 closure wound after continue outwards extract out lead sheath.Observation wound
Whether position continues is bled, such as also in bleed explanation sponge cover 4 and the hemostasis malposition of spheroid 5, it is necessary to continue to pull out
Drawstring 3 blocks wound.Until after hemostasis, cutting unnecessary long drawstring 3.
In order to strengthen haemostatic effect, the sponge cover 4 and hemostasis spheroid 5 surface are coated with hemostasis and anti-inflammation layer.
The hemostasis and anti-inflammation layer is calculated in parts by weight, including following components：20~45 parts of giant knotweed, gambir 20~28
Part, 5~6 parts of red sandalwood, 5~8 parts of silk cocoon, 10~15 parts of Radix Isatidis, 10~15 parts of luffa, 12~28 parts of radix boehmeriae, rhododendron micranthum 5
~10 parts, 5~8 parts of Radix Glycyrrhizae, 3~5 parts of oblongleaf garcinia seed oil, 0.18~0.2 part of emulsifying agent, 0.04~0.05 part of surfactant.
Embodiment 1
The hemostasis and anti-inflammation layer is calculated in parts by weight, including following components：20 parts of giant knotweed, 20 parts of gambir, red sandalwood 5
Part, 5 parts of silk cocoon, 10 parts of Radix Isatidis, 10 parts of luffa, 12 parts of radix boehmeriae, 5 parts of rhododendron micranthum, 5 parts of Radix Glycyrrhizae, 3 parts of oblongleaf garcinia seed oil, breast
0.18 part of agent, 0.04 part of surfactant.
The preparation method of above-mentioned hemostasis and anti-inflammation layer, comprises the following steps：
(1) take above-mentioned weight portion giant knotweed, silk cocoon, Radix Isatidis, luffa, radix boehmeriae and Radix Glycyrrhizae crush respectively after use
The mode of alcohol extraction is extracted 2 times, 3 days every time, merging filtrate after the leaching liquor filtering of each time is standby；
(2) red sandalwood is processed into bits, using soaking in Chinese liquor, leaches aubergine liquid, then uses charcoal absorption discoloration, must leach
Liquid is standby, wherein, the wine degree of white wine is 40% (V/V), soaks 5 hours；
(3) gambir dry extract is suspended with 1.5 times of warm water of weight, and water temperature is controlled at 50 DEG C, suspension is obtained standby；
(4) rhododendron micranthum decocts extraction 3 times in marmite, 50 minutes every time, filters to get filtrate, and being concentrated under reduced pressure into water content is
35% medicinal extract, is suspended with 50 DEG C of warm water, suspension is obtained standby；
(5) step (3) and suspension obtained in step (4) are mixed, is extracted with chloroform, obtain extract standby；
(6) by filtrate, leachate, extract and wood obtained in step (5) obtained in step (2) obtained in step (1)
Bamboo oil mixing is stirred, and emulsifying agent and surfactant are added while stirring, forms dispersed emulsion, i.e.,
Obtain Hemostatic Oral Liquid；The emulsifying agent uses Carbomer.Surfactant uses the mixture of ethanolamine salt and secondary alcohol APEO,
Both are according to quality proportioning 2:1 mixing.
(7) Hemostatic Oral Liquid obtained by step (6) is coated uniformly on sponge cover and hemostasis spherome surface forms hemostasis and anti-inflammation layer.
Embodiment 2
The hemostasis and anti-inflammation layer is calculated in parts by weight, including following components：30 parts of giant knotweed, 25 parts of gambir, red sandalwood 5.5
Part, 6 parts of silk cocoon, 12 parts of Radix Isatidis, 12 parts of luffa, 18 parts of radix boehmeriae, 7 parts of rhododendron micranthum, 6 parts of Radix Glycyrrhizae, 4 parts of oblongleaf garcinia seed oil, breast
0.19 part of agent, 0.04 part of surfactant.
The preparation method of above-mentioned hemostasis and anti-inflammation layer, comprises the following steps：
(1) take above-mentioned weight portion giant knotweed, silk cocoon, Radix Isatidis, luffa, radix boehmeriae and Radix Glycyrrhizae crush respectively after use
The mode of alcohol extraction is extracted 2 times, 2 days every time, merging filtrate after the leaching liquor filtering of each time is standby；
(2) red sandalwood is processed into bits, using soaking in Chinese liquor, leaches aubergine liquid, then uses charcoal absorption discoloration, must leach
Liquid is standby, wherein, the wine degree of white wine is 50% (V/V), soaks 4.5 hours；
(3) gambir dry extract is suspended with 1.5 times of warm water of weight, and water temperature is controlled at 52 DEG C, suspension is obtained standby；
(4) rhododendron micranthum decocts extraction 3 times in marmite, 45 minutes every time, filters to get filtrate, and being concentrated under reduced pressure into water content is
35% medicinal extract, is suspended with 52 DEG C of warm water, suspension is obtained standby；
(5) step (3) and suspension obtained in step (4) are mixed, is extracted with chloroform, obtain extract standby；
(6) by filtrate, leachate, extract and wood obtained in step (5) obtained in step (2) obtained in step (1)
Bamboo oil mixing is stirred, and emulsifying agent and surfactant are added while stirring, forms dispersed emulsion, i.e.,
Obtain Hemostatic Oral Liquid；The emulsifying agent uses Carbomer.Surfactant uses the mixture of ethanolamine salt and secondary alcohol APEO,
Both are according to quality proportioning 2:1 mixing.
(7) Hemostatic Oral Liquid obtained by step (6) is coated uniformly on sponge cover and hemostasis spherome surface forms hemostasis and anti-inflammation layer.
Embodiment 3
The hemostasis and anti-inflammation layer is calculated in parts by weight, including following components：45 parts of giant knotweed, 28 parts of gambir, red sandalwood 6
Part, 8 parts of silk cocoon, 15 parts of Radix Isatidis, 15 parts of luffa, 28 parts of radix boehmeriae, 10 parts of rhododendron micranthum, 8 parts of Radix Glycyrrhizae, 5 parts of oblongleaf garcinia seed oil, breast
0.2 part of agent, 0.05 part of surfactant.
The preparation method of above-mentioned hemostasis and anti-inflammation layer, comprises the following steps：
(1) take above-mentioned weight portion giant knotweed, silk cocoon, Radix Isatidis, luffa, radix boehmeriae and Radix Glycyrrhizae crush respectively after use
The mode of alcohol extraction is extracted 2 times, 2 days every time, merging filtrate after the leaching liquor filtering of each time is standby；
(2) red sandalwood is processed into bits, using soaking in Chinese liquor, leaches aubergine liquid, then uses charcoal absorption discoloration, must leach
Liquid is standby, wherein, the wine degree of white wine is 60% (V/V), soaks 4 hours；
(3) gambir dry extract is suspended with 1.5 times of warm water of weight, and water temperature is controlled at 55 DEG C, suspension is obtained standby；
(4) rhododendron micranthum decocts extraction 3 times in marmite, 40 minutes every time, filters to get filtrate, and being concentrated under reduced pressure into water content is
35% medicinal extract, is suspended with 55 DEG C of warm water, suspension is obtained standby；
(5) step (3) and suspension obtained in step (4) are mixed, is extracted with chloroform, obtain extract standby；
(6) by filtrate, leachate, extract and wood obtained in step (5) obtained in step (2) obtained in step (1)
Bamboo oil mixing is stirred, and emulsifying agent and surfactant are added while stirring, forms dispersed emulsion, i.e.,
Obtain Hemostatic Oral Liquid；The emulsifying agent uses Carbomer.Surfactant uses the mixture of ethanolamine salt and secondary alcohol APEO,
Both are according to quality proportioning 2:1 mixing.
(7) Hemostatic Oral Liquid obtained by step (6) is coated uniformly on sponge cover and hemostasis spherome surface forms hemostasis and anti-inflammation layer.
Clinical individual test example
Test example one, male patient Zhang, people from Jiangxi, 5 years old, leg arteries wound used this plugging device, around wound
Bloodstain is clean clearly, stops blooding immediately at wound, pain relief, checks any other infection do not occur after healing, and healing stage is relatively
It is short.
Test example two, women suffers from official, people from Chongqing, 15 years old, and abdominal aorta uses this plugging device, stops immediately at wound
Blood, pain relief checks any other infection do not occur after healing, healing stage is short, in vivo on inspection without any residue.
Test example three, male patient Jiang, people from Heilungkiang, 28 years old, aorta pectoralis used this plugging device, instant at wound
Hemostasis, pain relief checks any other infection do not occur after healing, healing stage is short, in vivo on inspection without any residue.
Presently preferred embodiments of the present invention is the foregoing is only, is not intended to limit the invention, it is all in essence of the invention
Any modification, equivalent and improvement made within god and principle etc., should be included within the scope of the present invention.
Claims (8)
1. a kind of blood vessel plugging device, it is characterised in that：Including outer barrel, push rod, the biodegradable drawstring of energy, sponge cover and hemostasis
Spheroid, the push rod is slidably matched in outer barrel, and drawstring one end is connected after sequentially passing through push rod and sponge cover with hemostasis spheroid, sea
Silk floss cover is movably arranged in outer barrel, and hemostatic ball physical efficiency is fitted into sponge cover, and sponge cover is strutted, and sponge cover inwall is provided with
For the stopper slot of spacing hemostasis spheroid, the sponge cover and hemostasis spherome surface are coated with hemostasis and anti-inflammation layer.
2. blood vessel plugging device according to claim 1, it is characterised in that：The sponge cover is truncated cone-shaped, and its top sets
There is the groove matched with push rod bottom.
3. blood vessel plugging device according to claim 2, it is characterised in that：The sponge cover is biodegradable sea
It is continuous.
4. blood vessel plugging device according to claim 2, it is characterised in that：The hemostasis spheroid uses biodegradable material
Material is made.
5. the blood vessel plugging device according to claim any one of 1-4, it is characterised in that the hemostasis and anti-inflammation layer is according to weight
Amount part calculates, including following components：20~45 parts of giant knotweed, 20~28 parts of gambir, 5~6 parts of red sandalwood, 5~8 parts of silk cocoon, plate are blue
10~15 parts of root, 10~15 parts of luffa, 12~28 parts of radix boehmeriae, 5~10 parts of rhododendron micranthum, 5~8 parts of Radix Glycyrrhizae, oblongleaf garcinia seed oil 3~
5 parts, 0.18~0.2 part of emulsifying agent, 0.04~0.05 part of surfactant.
6. the preparation method of a kind of hemostasis and anti-inflammation layer for blood vessel plugging device described in claim 5, it is characterised in that including
Following steps：
(1) 2~3 are extracted by the way of alcohol extraction after giant knotweed, silk cocoon, Radix Isatidis, luffa, radix boehmeriae and Radix Glycyrrhizae are crushed respectively
It is secondary, it is 2~3 days every time, merging filtrate after the leaching liquor filtering of each time is standby；
(2) red sandalwood is processed into bits, using soaking in Chinese liquor, leaches aubergine liquid, then uses charcoal absorption discoloration, obtains leachate standby
With；
(3) gambir dry extract is suspended with 1.5 times of warm water of weight, obtains suspension standby；
(4) rhododendron micranthum is decocted and extracted, and filtering obtains filtrate, is concentrated under reduced pressure into the medicinal extract that water content is 35~38%, mixed with warm water
It is outstanding, obtain suspension standby；
(5) step (3) and suspension obtained in step (4) are mixed, is extracted with chloroform, obtain extract standby；
(6) by filtrate, leachate, extract and garcinia multiflora obtained in step (5) obtained in step (2) obtained in step (1)
Oil mixing is stirred, and emulsifying agent and surfactant are added while stirring, forms dispersed emulsion, is obtained final product only
Blood；
(7) Hemostatic Oral Liquid obtained by step (6) is coated uniformly on sponge cover and hemostasis spherome surface forms hemostasis and anti-inflammation layer.
7. preparation method according to claim 6, it is characterised in that：The wine degree of white wine is arranged on 40 in the step (2)
~60% (V/V).
8. preparation method according to claim 6, it is characterised in that：The water temperature of warm water is 50 in the step (3) and (4)
~55 DEG C.
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| CN201710064609.9A CN106725695A (en) | 2017-02-04 | 2017-02-04 | A kind of blood vessel plugging device |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107802311A (en) * | 2017-11-20 | 2018-03-16 | 乐普（北京）医疗器械股份有限公司 | A kind of Wholly-degradable vessel sealing structure |
| CN109470822A (en) * | 2018-10-24 | 2019-03-15 | 苏州大学 | A kind of test device and its evaluation method of main artery wound hemostasis material and instrument sealing characteristics |
| CN116983027A (en) * | 2023-09-27 | 2023-11-03 | 苏州大学附属第二医院 | Vascular closure device |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107802311A (en) * | 2017-11-20 | 2018-03-16 | 乐普（北京）医疗器械股份有限公司 | A kind of Wholly-degradable vessel sealing structure |
| CN109470822A (en) * | 2018-10-24 | 2019-03-15 | 苏州大学 | A kind of test device and its evaluation method of main artery wound hemostasis material and instrument sealing characteristics |
| CN109470822B (en) * | 2018-10-24 | 2024-02-06 | 苏州大学 | Device for testing blocking performance of aortic trauma hemostatic material and instrument and evaluation method thereof |
| CN116983027A (en) * | 2023-09-27 | 2023-11-03 | 苏州大学附属第二医院 | Vascular closure device |
| CN116983027B (en) * | 2023-09-27 | 2024-04-19 | 苏州大学附属第二医院 | Vascular closure device |
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Application publication date: 20170531 |