CN106701382A - Female health care wine capable of improving intestinal flora - Google Patents
Female health care wine capable of improving intestinal flora Download PDFInfo
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- CN106701382A CN106701382A CN201710020637.0A CN201710020637A CN106701382A CN 106701382 A CN106701382 A CN 106701382A CN 201710020637 A CN201710020637 A CN 201710020637A CN 106701382 A CN106701382 A CN 106701382A
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12G—WINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
- C12G1/00—Preparation of wine or sparkling wine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
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Abstract
The invention aims to provide female health care wine capable of improving intestinal flora. The female health care wine comprises the following raw materials in parts by weight: 15-30 parts of lotus seed polysaccharide, 10-22 parts of oleuropein, 5-20 parts of scaphium scaphigerum polysaccharide, 5-10 parts of semen raphani polysaccharide and the balance of wine, totaling 100 parts. The female health care wine provided by the invention can adjust the disproportionality of probiotics and harmful bacteria in flora in the enteric cavity.
Description
Technical field
The invention belongs to field of health care products, and in particular to a kind of Female health wine of improvement gut flora.
Background technology
Live away from home miscellaneous microorganism in the intestines and stomach of Healthy People, and these microorganisms are referred to as gut flora.Human body
There is the bacterium of 1000-1150 kinds about 100,000,000,000,000 in enteron aisle, be 10 times of human body cell quantity, everyone at least 160 kinds dominant bacterias
Group.Gut flora is combined according to a certain percentage, is conditioned each other between each flora, depended on each other for existence, and forms a kind of ecological on quality and quantity
Balance.It is that can cause flora imbalance when organismic internal environment changes, severe patient occurs metabolic disorder.
The product of the regulating intestinal canal flora function of using at present includes profitable probliotics class product, prebiotic metaclass product and conjunction
Raw metaclass product.Wherein, prebiotic metaclass product has the advantages that shelf-stable, storage convenience, has no toxic side effect, and to regulation intestines
Road flora has positive role, can effectively suppress harmful bacteria propagation.
Patent ZL201510033640.7 disclose it is a kind of improve health food of gut flora and preparation method thereof, should
With probiotics powder agents such as Lactobacillus plantarums as primary raw material, compounding fungi extracts, modified dietary fiber are added health food
Body immunity, anti-inflammatory and antalgic, the Saussurea involucrata culture with anti-oxidant, radioresistance and the function such as antifatigue is remarkably improved to extract
Thing etc..This health products is by the effect of adding lactobacillus so as to reach regulating intestinal canal flora.
The content of the invention
It is an object of the invention to provide it is a kind of improve gut flora Female health wine, its formula according to China's dietotherapy,
The medicines and health protections such as traditional Chinese medicine are theoretical to instruct, and with reference to the principle of dynamics that human nutrition absorbs, used by each Chinese medicine material compatibility,
The probiotics of flora is out of proportion with harmful bacteria in regulation enteric cavity.
A kind of Female health wine of regulating intestinal canal flora, including following raw material：
Preferably, a kind of Female health wine of regulating intestinal canal flora, including following raw material：
It is furthermore preferred that a kind of Female health wine of regulating intestinal canal flora, including following raw material：
Most preferably, a kind of Female health wine of regulating intestinal canal flora, including following raw material：
Preferably, the weight part ratio of the Semen Nelumbinis polysaccharide, olive polyphenol, sterculia seed polysaccharide and radish seed polysaccharide is 20-28:
12-20:10-18:5-10。
It is furthermore preferred that the weight part ratio of the Semen Nelumbinis polysaccharide, olive polyphenol, sterculia seed polysaccharide and radish seed polysaccharide is 22-
25:15-18:12-17:6-9。
Health care method for preparing medicated wine of the invention, comprises the following steps：Radish seed polysaccharide is added in grape wine, stirring,
After being uniformly dissolved, Semen Nelumbinis polysaccharide, olive polyphenol, sterculia seed polysaccharide are sequentially added, after stirring, stand 36-48h, obtain health care
Wine crude product；Crude product is carried out into coarse filtration with flame filter press, then with 0.22-0.8 μm of micro-filtrate membrane filtration, it is filling, obtain health liquor.
Preferably, the microfiltration membranes pore size is 0.45-0.65 μm.0.22 μm of microfiltration membranes in aperture prevents bacterium from leading to
Cross, and 0.45 μm of microfiltration membranes in aperture can remove the solid suspended particle in wine.
It is furthermore preferred that the microfiltration membranes pore size is 0.45 μm.
Semen Nelumbinis polysaccharide be from the seed of Nymphaeceae nelumbium shell coring after fruit in extract and come, it can promote benefit
Raw bacterium propagation, suppresses pathogenic bacteria, and it also has promotion intestinal absorption work(, can strengthen intestine immunity function protection gastrointestinal mucosa barrier.
Olive polyphenol be from Burseraceae Canarium aiphyllium olive fruits extract, olive polyphenol and its by intestines
The product of road bacterial metabolism, the growth of susceptible microorganisms in energy selective control enteron aisle, selectively promotes profitable strain growth,
Suppress the propagation of harmful bacteria.Additionally, it also has antialcoholism function, protect liver can be played a part of.
Sterculia seed polysaccharide is to be extracted from the mature seed sterculia seed of Sterculiaceae duckweed mother-in-law's platymiscium and come, and it has anti-
The effect that scorching, treatment bacillary dysentery and suppression calcium oxalate crystal are formed.
Radish seed polysaccharide is to be extracted from the dry mature seed of crucifer radish and come, and can improve immunity of organism
The function of system, resistivity of the enhancing enteron aisle to harmful bacteria.Additionally, also having preservation, guarantor of the present invention can be effectively prevented
Active ingredient degraded in strong wine.
Compared with prior art, the beneficial effects of the invention are as follows：(1) middle the effective elements of the medicine is added directly into grape wine
In, improve the defect that soak time is long, active ingredient dissolution rate is low and dissolution component is miscellaneous in Traditional health care wine preparation technology；
(2) with grape wine as base liquor, its category alkaline drink wine, Alcohol degree is low, is adapted to women, can adjust constitution acid-base value；(3)
Semen Nelumbinis polysaccharide, olive polyphenol, sterculia seed polysaccharide and four kinds of medicines of radish seed polysaccharide are compatible, the probiotics of flora in regulation enteric cavity
It is out of proportion with harmful bacteria；(4) raw material is all belonging to the medicine-food two-purpose that food and medicine Surveillance Authority specifies and can be used for health care food
The material of product, has no toxic side effect.
Specific embodiment
In order that those skilled in the art more fully understands technical scheme, with reference to specific embodiment
The present invention is further described, but embodiments of the present invention are not limited only to this.
Embodiment 1
A kind of Female health wine of regulating intestinal canal flora, including following raw material：15 parts of Semen Nelumbinis polysaccharide, olive polyphenol
16 parts, 5 parts of sterculia seed polysaccharide, 5 parts of radish seed polysaccharide, balance of grape wine, altogether 1000 parts.
Preparation method：Radish seed polysaccharide is added in grape wine, after stirring, being uniformly dissolved, sequentially add Semen Nelumbinis polysaccharide,
Olive polyphenol, sterculia seed polysaccharide, after stirring, stand 36h, obtain health liquor crude product；Crude product is carried out slightly with flame filter press
Filter, then with 0.22 μm of micro-filtrate membrane filtration, it is filling, obtain health liquor.
Embodiment 2
A kind of Female health wine of regulating intestinal canal flora, including following raw material：23 parts of Semen Nelumbinis polysaccharide, olive polyphenol
22 parts, 20 parts of sterculia seed polysaccharide, 10 parts of radish seed polysaccharide, balance of grape wine, altogether 1000 parts.
Preparation method：Radish seed polysaccharide is added in grape wine, after stirring, being uniformly dissolved, sequentially add Semen Nelumbinis polysaccharide,
Olive polyphenol, sterculia seed polysaccharide, after stirring, stand 42h, obtain health liquor crude product；Crude product is carried out slightly with flame filter press
Filter, then with 0.6 μm of micro-filtrate membrane filtration, it is filling, obtain health liquor.
Embodiment 3
A kind of Female health wine of regulating intestinal canal flora, including following raw material：30 parts of Semen Nelumbinis polysaccharide, olive polyphenol
10 parts, 9 parts of sterculia seed polysaccharide, 8 parts of radish seed polysaccharide, balance of grape wine, altogether 1000 parts.
Preparation method：Radish seed polysaccharide is added in grape wine, after stirring, being uniformly dissolved, sequentially add Semen Nelumbinis polysaccharide,
Olive polyphenol, sterculia seed polysaccharide, after stirring, stand 48h, obtain health liquor crude product；Crude product is carried out slightly with flame filter press
Filter, then with 0.8 μm of micro-filtrate membrane filtration, it is filling, obtain health liquor.
Embodiment 4
A kind of Female health wine of regulating intestinal canal flora, including following raw material：27 parts of Semen Nelumbinis polysaccharide, olive polyphenol
19 parts, 17 parts of sterculia seed polysaccharide, 6 parts of radish seed polysaccharide, balance of grape wine, altogether 1000 parts.
Preparation method：Radish seed polysaccharide is added in grape wine, after stirring, being uniformly dissolved, sequentially add Semen Nelumbinis polysaccharide,
Olive polyphenol, sterculia seed polysaccharide, after stirring, stand 48h, obtain health liquor crude product；Crude product is carried out slightly with flame filter press
Filter, then with 0.45 μm of micro-filtrate membrane filtration, it is filling, obtain health liquor.
Embodiment 5
A kind of Female health wine of regulating intestinal canal flora, including following raw material：22 parts of Semen Nelumbinis polysaccharide, olive polyphenol
16 parts, 15 parts of sterculia seed polysaccharide, 7 parts of radish seed polysaccharide, balance of grape wine, altogether 1000 parts.
Preparation method：Radish seed polysaccharide is added in grape wine, after stirring, being uniformly dissolved, sequentially add Semen Nelumbinis polysaccharide,
Olive polyphenol, sterculia seed polysaccharide, after stirring, stand 48h, obtain health liquor crude product；Crude product is carried out slightly with flame filter press
Filter, then with 0.45 μm of micro-filtrate membrane filtration, it is filling, obtain health liquor.
Comparative example 1
A kind of Female health wine of regulating intestinal canal flora, including following raw material：22 parts of Semen Nelumbinis polysaccharide, the sterculia seed are more
Sugared 15 parts, 7 parts of radish seed polysaccharide, balance of grape wine, altogether 1000 parts.
Preparation method：Radish seed polysaccharide is added in grape wine, after stirring, being uniformly dissolved, sequentially add Semen Nelumbinis polysaccharide,
Olive polyphenol, sterculia seed polysaccharide, after stirring, stand 48h, obtain health liquor crude product；Crude product is carried out slightly with flame filter press
Filter, then with 0.45 μm of micro-filtrate membrane filtration, it is filling, obtain health liquor.
Comparative example 2
A kind of Female health wine of regulating intestinal canal flora, including following raw material：22 parts of Semen Nelumbinis polysaccharide, olive polyphenol
16 parts, 7 parts of radish seed polysaccharide, balance of grape wine, altogether 1000 parts.
Preparation method：Radish seed polysaccharide is added in grape wine, after stirring, being uniformly dissolved, sequentially add Semen Nelumbinis polysaccharide,
Olive polyphenol, sterculia seed polysaccharide, after stirring, stand 48h, obtain health liquor crude product；Crude product is carried out slightly with flame filter press
Filter, then with 0.45 μm of micro-filtrate membrane filtration, it is filling, obtain health liquor.
The efficacy test of embodiment 6
60 intestinal bacilli illness mouse are taken, 1,2 groups of model control group, embodiment 1,4,5 and comparative example is randomly divided into, separately
Take 10 normal mouses and be set to Normal group.Health liquor gastric infusion prepared by embodiment 1,4,5 is in embodiment 1,4,5
Group, health liquor prepared by same 1,2 groups of gastric infusion comparative examples 1,2 of comparative example, dosage is 1g.kg-1, Normal group
Isometric distilled water is given with model control group, each group is administered once daily, continuous 15 days.After last dose 24h, aseptic
Under the conditions of, take out ileum and cecal content gradient dilution to 10-9, it is inoculated on selective medium respectively, count large intestine bar
The quantity of bacterium, lactic acid bacteria and Bifidobacterium.
The Female health wine of the regulating intestinal canal flora of the present invention of table 1 is to intestinal bacilli illness model mice normal intestinal flora number
Influence.
Note：*(p<0.05) compare with Normal group, # (p<0.05) compare with model control group.
The result of table 1 shows, after taking the health liquor of the embodiment of the present invention 1,4 and 5, various embodiments of the present invention group gut flora
The gut flora number of imbalance model mice returns to normal level, with significant difference (p compared with model control group<
0.05).There was no significant difference compared with model control group for the gut flora number of comparative example group intestinal bacilli illness model mice
(p<0.05), its gut flora number for having significant difference intestinal bacilli illness model mice with Normal group is returned to just
Ordinary water is put down, with significant difference (p compared with model control group<0.05).Thus illustrate, health liquor of the present invention has regulation
The effect of gut flora.
Claims (7)
1. a kind of Female health wine of regulating intestinal canal flora, it is characterised in that including following raw material：
2. a kind of Female health wine of regulating intestinal canal flora as claimed in claim 1, it is characterised in that including following weight portion
Raw material：
3. a kind of Female health wine of regulating intestinal canal flora as claimed in claim 1, it is characterised in that including following weight portion
Raw material：
4. the Female health wine of a kind of regulating intestinal canal flora as described in claim any one of 1-3, it is characterised in that including with
Lower raw material：
5. a kind of Female health wine of regulating intestinal canal flora as claimed in claim 1 or 2, it is characterised in that the lotus seeds are more
The weight part ratio of sugar, olive polyphenol, sterculia seed polysaccharide and radish seed polysaccharide is 20-28:12-20:10-18:5-10.
6. a kind of Female health wine of regulating intestinal canal flora as claimed in claim 5, it is characterised in that the Semen Nelumbinis polysaccharide,
The weight part ratio of olive polyphenol, sterculia seed polysaccharide and radish seed polysaccharide is 22-25:15-18:12-17:6-9.
7. a kind of Female health wine of the regulating intestinal canal flora as described in claim any one of 1-3, it is characterised in that its preparation
Method is comprised the following steps：Radish seed polysaccharide is added in grape wine, after stirring, being uniformly dissolved, sequentially add Semen Nelumbinis polysaccharide,
Olive polyphenol, sterculia seed polysaccharide, after stirring, stand 36-48h, obtain health liquor crude product；Crude product is carried out with flame filter press
Coarse filtration, then with 0.22-0.8 μm of micro-filtrate membrane filtration, it is filling, obtain health liquor.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710020637.0A CN106701382A (en) | 2017-01-11 | 2017-01-11 | Female health care wine capable of improving intestinal flora |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710020637.0A CN106701382A (en) | 2017-01-11 | 2017-01-11 | Female health care wine capable of improving intestinal flora |
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| CN106701382A true CN106701382A (en) | 2017-05-24 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201710020637.0A Pending CN106701382A (en) | 2017-01-11 | 2017-01-11 | Female health care wine capable of improving intestinal flora |
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Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102604797A (en) * | 2011-01-20 | 2012-07-25 | 云南龙润药业有限公司 | Beautifying and detoxifying wine and its preparation method |
| CN102660420A (en) * | 2012-05-21 | 2012-09-12 | 王德俊 | Health-preserving dry red wine |
| CN105199888A (en) * | 2014-06-18 | 2015-12-30 | 廖莲 | Grape medicinal liquor preparing method |
| CN105695251A (en) * | 2014-11-27 | 2016-06-22 | 衡阳市旺人食品实业有限公司 | Hawthorn radish seed health care wine and preparation method thereof |
| CN105695195A (en) * | 2016-01-28 | 2016-06-22 | 佛山市聚成生化技术研发有限公司 | Health-care red wine for females |
| CN105695193A (en) * | 2016-01-28 | 2016-06-22 | 佛山市聚成生化技术研发有限公司 | Red date polysaccharide wine |
| CN106190681A (en) * | 2016-08-23 | 2016-12-07 | 常熟市吉健葡萄科技有限公司 | There is the grape beverage of Chinese medicine ingredients |
-
2017
- 2017-01-11 CN CN201710020637.0A patent/CN106701382A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102604797A (en) * | 2011-01-20 | 2012-07-25 | 云南龙润药业有限公司 | Beautifying and detoxifying wine and its preparation method |
| CN102660420A (en) * | 2012-05-21 | 2012-09-12 | 王德俊 | Health-preserving dry red wine |
| CN105199888A (en) * | 2014-06-18 | 2015-12-30 | 廖莲 | Grape medicinal liquor preparing method |
| CN105695251A (en) * | 2014-11-27 | 2016-06-22 | 衡阳市旺人食品实业有限公司 | Hawthorn radish seed health care wine and preparation method thereof |
| CN105695195A (en) * | 2016-01-28 | 2016-06-22 | 佛山市聚成生化技术研发有限公司 | Health-care red wine for females |
| CN105695193A (en) * | 2016-01-28 | 2016-06-22 | 佛山市聚成生化技术研发有限公司 | Red date polysaccharide wine |
| CN106190681A (en) * | 2016-08-23 | 2016-12-07 | 常熟市吉健葡萄科技有限公司 | There is the grape beverage of Chinese medicine ingredients |
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Application publication date: 20170524 |