CN106693216A - Titanium alloy gold label implant and gold label syringe - Google Patents
Titanium alloy gold label implant and gold label syringe Download PDFInfo
- Publication number
- CN106693216A CN106693216A CN201710067249.8A CN201710067249A CN106693216A CN 106693216 A CN106693216 A CN 106693216A CN 201710067249 A CN201710067249 A CN 201710067249A CN 106693216 A CN106693216 A CN 106693216A
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- China
- Prior art keywords
- titanium alloy
- implant
- layer
- gold label
- sample body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/103—Treatment planning systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
- A61N2005/1051—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam using an active marker
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N2005/1092—Details
- A61N2005/1096—Elements inserted into the radiation path placed on the patient, e.g. bags, bolus, compensators
Abstract
The invention discloses a titanium alloy gold label implant which comprises a gold label body, wherein the gold label body is made of a titanium alloy; the gold label body comprises an arc-shaped connecting rod; spheres are fixedly arranged at two ends of the arc-shaped connecting rod respectively; and the diameters of the spheres are greater than the diameter of the arc-shaped connecting rod. The stability of the gold label body and implanted tumor tissues or surrounding specific soft tissues is improved through the spheres at two ends of the arc-shaped connecting rod, so that the gold label body is not easy to move and the treatment security and accuracy are improved. The gold label body is not easy to move, so that the probability of a radiation damage or accident due to the fact that the gold label body moves and the irradiation position changes in the treatment process is reduced. The invention further provides a gold label syringe adopting the titanium alloy gold label implant.
Description
Technical field
The present invention relates to medical instruments field, more particularly to a kind of titanium alloy gold mark implant and gold mark emitter.
Background technology
In order to the tumour irradiated in high precision in soft tissue is marked, it is necessary to be implanted into gold in intra-tumor or side, by gold in treatment
Target follows the trail of the dynamic tracing realized to tumour.
After gold mark implantation one week, metastable geometrical relationship is formed with tumour, golden cursor position is determined in the treatment
The position of tumour is determined that, golden target degree of moving also just represents the dynamic degree of tumour.
But gold is marked on implantation tumour tissue or around it after specific soft tissue, gold mark thing is susceptible to movement, if displacement
Occur before the treatment, risk will not be brought, but the decline for irradiating precision may be caused, can be solved by being implanted into gold mark again
Certainly；If being shifted in the treatment, the security and accuracy for the treatment of, and the mobile then irradiation position of gold mark may be influenceed
Change, radioactive damage even accident may be caused.Therefore, no matter gold mark displacement occurs before the treatment, or in treatment,
Will actively take measures, it is to avoid the security and accuracy for the treatment of are affected.
The content of the invention
It is an object of the invention to provide a kind of titanium alloy gold mark implant and gold mark emitter, to solve in the prior art
There is above-mentioned technical problem.
The titanium alloy gold mark implant that the present invention is provided, including golden sample body, the golden sample body are made up of titanium alloy, institute
Golden sample body is stated including arc-shaped connecting rod, the arc-shaped connecting rod two ends are installed with spheroid respectively, the spheroid with diameter greater than
The diameter of the arc-shaped connecting rod.
Further, the golden sample body is provided with projection.
Further, it is described raised for cross is raised.
Further, it is described raised for herringbone is raised.
Further, it is described raised for V-shaped is raised.
Further, the golden sample body is provided with Nano medication layer.
Further, the Nano medication layer is adhered on the golden sample body by connecting oxidant layer.
Further, the connection oxidant layer is made a living thing adhesive phase.
Further, the bioadhesive oxidant layer be fibrinogen layer, thrombin layer, casein layer, chitin layer or
Chitosan layer.
The titanium alloy gold mark implant that the present invention is provided, has the following advantages that：
Increase the tumor tissues or specific soft around it of golden sample body and implantation by the spheroid at arc-shaped connecting rod two ends
The stability of tissue, makes golden sample body be not susceptible to movement, the security and accuracy for the treatment of is improved, because golden sample body is difficult
Mobile, reduction makes irradiation position change because golden sample body is moved over the course for the treatment of, may cause radioactive damage
The probability that even accident occurs.
In addition, present invention also offers a kind of gold mark emitter, including injection needle body and the gold mark implantation of above-mentioned titanium alloy
Body, the golden sample body is placed in the injection needle body.
Brief description of the drawings
In order to illustrate more clearly of the specific embodiment of the invention or technical scheme of the prior art, below will be to specific
The accompanying drawing to be used needed for implementation method or description of the prior art is briefly described, it should be apparent that, in describing below
Accompanying drawing is some embodiments of the present invention, for those of ordinary skill in the art, before creative work is not paid
Put, other accompanying drawings can also be obtained according to these accompanying drawings.
Fig. 1 is the structural front view of the titanium alloy gold mark implant that the embodiment of the present invention one is provided；
Fig. 2 is the structural front view of the titanium alloy gold mark implant that the embodiment of the present invention two is provided；
Fig. 3 is the structural front view of the titanium alloy gold mark implant that the embodiment of the present invention three is provided；
Fig. 4 is the structural front view of the titanium alloy gold mark implant that the embodiment of the present invention four is provided；
Fig. 5 is the structural front view of the titanium alloy gold mark implant that the embodiment of the present invention five is provided；
Fig. 6 is the partial enlarged drawing A of Fig. 5；
The structural front view of the gold mark emitter that Fig. 7 embodiment of the present invention six is provided；
Fig. 8 is the partial enlarged drawing B of Fig. 7.
Reference：
1- gold sample bodies；11- arc-shaped connecting rods；12- spheroids；
13- is raised；2- Nano medications layer；3- connects oxidant layer；
4- injects needle body；41- sleeve pipes；42- hollow handles；
43- propellers；411- tips；44- push rod；
45- push-and-pull heads.
Specific embodiment
Technical scheme is clearly and completely described below in conjunction with accompanying drawing, it is clear that described implementation
Example is a part of embodiment of the invention, rather than whole embodiments.Based on the embodiment in the present invention, ordinary skill
The every other embodiment that personnel are obtained under the premise of creative work is not made, belongs to the scope of protection of the invention.
In the description of the invention, it is necessary to explanation, term " " center ", " on ", D score, "left", "right", " vertical ",
The orientation or position relationship of the instruction such as " level ", " interior ", " outward " be based on orientation shown in the drawings or position relationship, merely to
Be easy to the description present invention and simplify describe, rather than indicate imply signified device or element must have specific orientation,
With specific azimuth configuration and operation, therefore it is not considered as limiting the invention.Additionally, term " first ", " second ",
" the 3rd " is only used for describing purpose, and it is not intended that indicating or implying relative importance.
In the description of the invention, it is necessary to illustrate, unless otherwise clearly defined and limited, term " installation ", " phase
Company ", " connection " should be interpreted broadly, for example, it may be being fixedly connected, or being detachably connected, or be integrally connected；Can
Being to mechanically connect, or electrically connect；Can be joined directly together, it is also possible to be indirectly connected to by intermediary, Ke Yishi
Two connections of element internal.For the ordinary skill in the art, above-mentioned term can as the case may be understood
Concrete meaning in the present invention.
Embodiment one：
Fig. 1 is the structural front view of the titanium alloy gold mark implant that the embodiment of the present invention one is provided；As shown in figure 1, this hair
The titanium alloy gold mark implant of bright offer, including golden sample body 1, the golden sample body 1 are made up of titanium alloy, the golden sample body
1 includes arc-shaped connecting rod 11, and the two ends of the arc-shaped connecting rod 11 are installed with spheroid 12 respectively, the spheroid 12 with diameter greater than institute
State the diameter of connecting rod 11.
Titanium is a kind of important structural metal for growing up the 1950's, and titanium alloy is because high, anti-corrosion with intensity
The features such as property is good, heat resistance is high and be widely used in every field.Many countries all recognize the weight of titanium alloy material in the world
The property wanted, researchs and develops to it in succession, and is applied.50~sixties of 20th century, mainly develop aviation hair
The high-temperature titanium alloy of motivation and the structural titanium alloy of body, develop a collection of corrosion resistant Ti alloy the seventies, since the eighties,
Corrosion resistant Ti alloy and high-strength titanium alloy are further developed.Titanium alloy is mainly used in making aircraft engine compressor part,
Secondly it is the structural member of rocket, guided missile and high-speed aircraft.
The titanium alloy gold mark implant that the present invention is provided, has the following advantages that：
Increase tumor tissues or the spy around it of golden sample body and implantation by the spheroid 12 at the two ends of arc-shaped connecting rod 11
Determine the stability of soft tissue, golden sample body is not susceptible to movement, the security and accuracy for the treatment of are improved, due to golden sample body
Not easily shifted, reduction makes irradiation position change because golden sample body is moved over the course for the treatment of, may cause radioactivity
Damage the probability that even accident occurs.
Embodiment two：
Fig. 2 is the structural front view of the titanium alloy gold mark implant that the embodiment of the present invention two is provided；As shown in Fig. 2 this hair
The titanium alloy gold mark implant of bright offer, including golden sample body 1, the golden sample body 1 are made up of titanium alloy, the golden sample body
1 includes arc-shaped connecting rod 11, and the two ends of the arc-shaped connecting rod 11 are installed with spheroid 12 respectively, the spheroid 12 with diameter greater than institute
State the diameter of arc-shaped connecting rod 11.
The length of golden sample body 1 is 0.1mm-10mm, a diameter of 0.1mm-1.5mm.
The golden sample body 1 is provided with raised 13.
Described raised 13 is raised cross.
The tumor tissues for further being increased by raised 13 on golden sample body 1 and being implanted into or the specific soft tissue around it
Stability.
Embodiment three：
Fig. 3 is the structural front view of the titanium alloy gold mark implant that the embodiment of the present invention three is provided；As shown in figure 3, this hair
The titanium alloy gold mark implant of bright offer, including golden sample body 1, the golden sample body 1 are made up of titanium alloy, the golden sample body
1 includes arc-shaped connecting rod 11, and the two ends of the arc-shaped connecting rod 11 are installed with spheroid 12 respectively, the spheroid 12 with diameter greater than institute
State the diameter of arc-shaped connecting rod 11.
The golden sample body 1 is provided with raised 13.
Described raised 13 is raised herringbone.
Example IV：
Fig. 4 is the structural front view of the titanium alloy gold mark implant that the embodiment of the present invention four is provided；As shown in figure 4, this hair
The titanium alloy gold mark implant of bright offer, including golden sample body 1, the golden sample body 1 are made up of titanium alloy, the golden sample body
1 includes arc-shaped connecting rod 11, and the two ends of the arc-shaped connecting rod 11 are installed with spheroid 12 respectively, the spheroid 12 with diameter greater than institute
State the diameter of arc-shaped connecting rod 11.
The golden sample body 1 is provided with raised 13.
Described raised 13 is raised V-shaped.
It should be noted that raised 13 shape and structure can also be used in addition to cross, herringbone and V-shaped
Other shapes, just differ a citing herein.
Embodiment five：
Fig. 5 is the structural front view of the titanium alloy gold mark implant that the embodiment of the present invention five is provided, and Fig. 6 is the part of Fig. 5
Enlarged drawing A, as seen in figs. 5-6, the titanium alloy gold mark implant that the present invention is provided, including golden sample body 1, the golden sample body 1
It is made up of titanium alloy, the golden sample body 1 includes arc-shaped connecting rod 11, and the two ends of the arc-shaped connecting rod 11 are installed with spheroid respectively
12, the diameter with diameter greater than the arc-shaped connecting rod 11 of the spheroid 12.
The golden sample body 1 is provided with Nano medication layer 2.
The Nano medication layer 2 is adhered on the golden sample body 1 by connecting oxidant layer 3.
The connection oxidant layer 3 is biological adhesive phase.
The bioadhesive oxidant layer is fibrinogen layer, thrombin layer, casein layer, chitin layer or chitosan layer.
Collagen is boiomacromolecule, the main component in animal connective tissue, be also mammal in-vivo content most
The many, functional protein that distribution is most wide, accounts for the 25%~30% of total protein, and some organisms are even as high as more than 80%.
Collagen species is more, and common type is I type, II type, III type, V type and Ⅺ type.
Collagen because with good biocompatibility, biodegradable and bioactivity, therefore in food, doctor
The fields such as medicine, organizational project, cosmetics are widely applied.The collagen health products " donkey-hide gelatin " of such as Chinese tradition, mainly
With donkey hide as raw material (being exactly in fact contained collagen in donkey hide), with nourishing health function higher, have Chinese medicine Triratna it
One good reputation.
Fibrin ferment：It is a kind of in human body anti-freezing, promotees the bioactivity egg of important role in solidifying coagulation cascade reaction
In vain.
Casein layer：Casein is a kind of associated proteins of phosphorous calcium, and acid labile can be precipitated when pH is relatively low.
Casein be mammal include cow, the main protein in sheep and people's milk, also known as：Casein, casein, cheese
Element.
Chitin layer：Chitin (chitin) is also known as chitin.For N-acetyl-glucosamine connects the knot being polymerized by β
Structure homopolysaccharide.It is widely present in the cell wall of the shell of shellfish, the crust of insect and fungi, exists in some green algas
In；It is primarily used to as support body skeleton, and plays protection to body.
Chitosan layer：Shitosan (chitosan), also known as chitosan, is the chitin being widely present by nature
(chitin) obtained by deacetylation, chemical name is Chitosan (1-4) -2- amino-B-D glucose.
From 1859, after Frenchman Rouget obtains shitosan first, the biological functionality and phase of this natural polymer
The premium properties such as capacitive, blood compatibility, security, microbic resolvability by all trades and professions extensive concern, medicine, food,
The application study of the numerous areas such as chemical industry, cosmetics, water process, METAL EXTRACTION and recovery, biochemical and biomedical engineering is obtained
Major progress.For patient, shitosan reducing blood lipid, the existing research report of hypoglycemic effect.Meanwhile, shitosan is by as increasing
Thick dose, fruit glaze agent list in state food additive use standard GB-2760.
Nano medication, to refer to and directly manipulate atom, molecule or atomic group, micel by certain microfabrication mode, makes
It rearranges combination, forms the new material with nanoscale or structure, and one kind has with the kin phosphorus of biomembrane
The medicine of lipid bilayer structure carrier.
In drug research field, due to the continuous infiltration and influence of nanometer technology, trigger the field depth of drug field one remote
Revolution, so as to occur in that Nano medication this new term.
Nano medication refers to nanoscale high molecular nanometer grain (nano-particles, NP), nanosphere
(nano.spheres NS), nanocapsule (nano-capsules, NC) etc. are carrier, are combined together in a certain way with medicine
The medicine being made afterwards, its particle diameter can exceed that 100nm, but should be generally less than 500nm.Nano medication can also be directly by raw material
The nanoparticle that medicine is processed into.
The application of Nano medication not only improves the physicochemical property of pharmaceutical dosage form, and improves the targeting of medicine, delays
Property released etc..Research display nano particle has and directly act on cancer cell by high concentration medicine and avoid the energy of health tissues
Power.
The characteristic of Nano medication：
1) targeting under magnetic fields is combined using nano-carrier with magnetisable material, makes it have magnetic.
Meanwhile, by external complementary field, or by the materials such as conduit, support of the implantation with magnetic field effect of performing the operation in body
Interior specific region forms magnetic field.By target organ in magnetic field, magnetic nano-carrier distribution in vivo is controlled with this, make it
Integrated distribution is in target organ.
Having research display magnetic nano-carrier can make its chemotherapeutics orientation for being loaded concentrate on targeting portion by magnetic field
Position (tumor tissues), improves drug concentration, the enhancing therapeutic effect of targeting moiety, while the drug concentration at other positions is reduced,
Reduce toxicity.
2) active targeting is by monoclonal antibody covalent cross-linking or is adsorbed onto nanoparticle surface, and formation is received with immunocompetence
The grain of rice, and be applied to the research of antineoplastic and also achieve certain result.
2nd, the controlled capability of Nano medication
Because of many chemotherapeutics half-life shorts, maintain its effective antitumor concentration-time shorter.Some chemotherapeutics are only right
Tumour cell in specific proliferating cycle is played a role, and the cell of other proliferating cycles is not played a role, but tumour
The cell cycle of cell is typically nonsynchronous, therefore, maintain long period effective blood concentration also non-for oncotherapy
It is often important.
3rd, Nano medication absorptivity is high
Nano medication is favorably improved the absorptivity of medicine, and drug-carrying nanometer particle can change film operative mechanism, increase medicine
To the permeability of biomembrane, be conducive to the performance of Drug Percutaneous Absorption and intracellular drug effect.
Such as loading the nanoparticle of antineoplastic adriamycin can make more common 10 times of the adriamycin increase of its drug effect, and reason is
The adhesiveness of drug-carrying nanometer particle and its small particle diameter can extend the medicine retention time, increase medicine and intestinal wall time of contact and
Contact area, improves the bioavailability of its oral absorption.
4th, nanometer antineoplastic is represented
The clinical antitumor agents for being currently based on nanometer technology are represented as liposomal doxorubicin, albumin combination type Japanese yew
Alcohol.
Wherein liposomal doxorubicin combines the bio distribution for changing medicine with lipidic nanoparticles for adriamycin, from
And the cardiac toxic of adriamycin is reduced, albumin combination type taxol also eliminates chemotherapeutics and organic solvent polyoxyethylene
The adverse reaction of castor oil, it may not be necessary to directly applied using any solvent.
The medicine being currently in development also has BIND-014, and the medicine is targeting PSMA (PSMA)
Nanoparticulate drug containing docetaxel.
The display medicine is studied and good security, tolerance and effectively has late been achieved in patients with solid tumor
The result of property.
The Bb cells that the nano particle of another medicine filling gold element is proved to kill in the people's cell of culture drench
Bar knurl, can suppress the growth of human B cell lymthoma in Mice Body in the case of non-chemotherapy.
And the targeting particle for being coated with Bladder cancer specific ligand and load taxol researched and developed is resistance to by 3 times of maximums
By dosage drug delivery to the mouse for having transplanted patient tumors, obtain good disease control and adverse reaction be resistant to
Receive.
In terms of the treatment of Huppert's disease, nano particle also show certain potentiality, overcome using how soft
Than the resistance problems that star causes, one of resistance acceptor Vla-4-4 (VLA-4) and micro-loop are avoided by nano particle
Border interacts, and more directly, more effectively targeting is in tumour.
Embodiment six：
Fig. 7 is the structural front view of the gold mark emitter that the embodiment of the present invention six is provided, and Fig. 8 is the partial enlarged drawing of Fig. 7
B；As shown in Figs. 7-8, the gold mark emitter that the present invention is provided, including injection needle body 4 and above-mentioned titanium alloy gold mark implant,
The golden sample body 1 is placed in the injection needle body 4.
The injection needle body 4 includes sleeve pipe 41, hollow handle 42, propeller 43 and push rod 44, and the end of sleeve pipe 41 is provided with
Tip 411, the other end of sleeve pipe 41 connection hollow handle 42, propeller 43 is arranged in sleeve pipe 41, and propeller 43 is away from the end of sleeve pipe 41
The space for placing golden sample body 1 is left between portion, the one end of push rod 44 is connected with propeller 43, the other end of push rod 44 is worn
Cross hollow handle 42 and push-and-pull first 45 is installed.
When using, golden sample body 1 is loaded in the space of the leading section of sleeve pipe 41, sleeve pipe 41 is punctured to needs the disease of mark
Become in organ, promote push-and-pull first 45 to drive push rod 44 so as to drive propeller 43 that golden sample body 1 is released into sleeve pipe and disease is injected
Become in organ.
Finally it should be noted that：Various embodiments above is merely illustrative of the technical solution of the present invention, rather than its limitations；To the greatest extent
Pipe has been described in detail with reference to foregoing embodiments to the present invention, it will be understood by those within the art that：Its according to
The technical scheme described in foregoing embodiments can so be modified, or which part or all technical characteristic are entered
Row equivalent；And these modifications or replacement, the essence of appropriate technical solution is departed from various embodiments of the present invention technology
The scope of scheme.
Claims (10)
1. a kind of titanium alloy gold marks implant, it is characterised in that including golden sample body, the golden sample body is made up of titanium alloy,
The golden sample body includes arc-shaped connecting rod, and the arc-shaped connecting rod two ends are installed with spheroid respectively, and the diameter of the spheroid is big
In the diameter of the arc-shaped connecting rod.
2. titanium alloy gold according to claim 1 marks implant, it is characterised in that the golden sample body is provided with projection.
3. titanium alloy gold according to claim 2 marks implant, it is characterised in that described raised for cross is raised.
4. titanium alloy gold according to claim 2 marks implant, it is characterised in that described raised for herringbone is raised.
5. titanium alloy gold according to claim 2 marks implant, it is characterised in that described raised for V-shaped is raised.
6. titanium alloy gold according to claim 1 marks implant, it is characterised in that the golden sample body is provided with a nanometer medicine
Nitride layer.
7. titanium alloy gold according to claim 6 marks implant, it is characterised in that the Nano medication layer passes through bridging agent
Layer is adhered on the golden sample body.
8. titanium alloy according to claim 7 gold mark implant, it is characterised in that the connection oxidant layer is made a living thing adhesive
Layer.
9. titanium alloy gold according to claim 8 marks implant, it is characterised in that the bioadhesive oxidant layer is fiber egg
White original layer, thrombin layer, casein layer, chitin layer or chitosan layer.
10. a kind of gold marks emitter, it is characterised in that including injection needle body and according to any one of claim 1-9
Titanium alloy gold mark implant, the golden sample body is placed in the injection needle body.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710067249.8A CN106693216A (en) | 2017-02-06 | 2017-02-06 | Titanium alloy gold label implant and gold label syringe |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710067249.8A CN106693216A (en) | 2017-02-06 | 2017-02-06 | Titanium alloy gold label implant and gold label syringe |
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| Publication Number | Publication Date |
|---|---|
| CN106693216A true CN106693216A (en) | 2017-05-24 |
Family
ID=58910358
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| CN201710067249.8A Pending CN106693216A (en) | 2017-02-06 | 2017-02-06 | Titanium alloy gold label implant and gold label syringe |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN113289268A (en) * | 2021-05-25 | 2021-08-24 | 河南科技大学第一附属医院 | Reusable radiotherapy gold mark positioner, positioning controller and positioning device |
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| CN207076027U (en) * | 2017-02-06 | 2018-03-09 | 中国人民解放军总医院 | Titanium alloy gold mark implant and gold mark emitter |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113289268A (en) * | 2021-05-25 | 2021-08-24 | 河南科技大学第一附属医院 | Reusable radiotherapy gold mark positioner, positioning controller and positioning device |
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