CN106691380A - OCT probe used for optical path automatic calibration - Google Patents

OCT probe used for optical path automatic calibration Download PDF

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Publication number
CN106691380A
CN106691380A CN201611203292.4A CN201611203292A CN106691380A CN 106691380 A CN106691380 A CN 106691380A CN 201611203292 A CN201611203292 A CN 201611203292A CN 106691380 A CN106691380 A CN 106691380A
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CN
China
Prior art keywords
lens
oct probe
grin
optical path
light path
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201611203292.4A
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Chinese (zh)
Inventor
于波
贾海波
胡思宁
田洁
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Tianjin Hengyu Medical Technology Co ltd
2nd Affiliated Hospital Of Harbin Medical University
Original Assignee
Tianjin Hengyu Medical Technology Co ltd
2nd Affiliated Hospital Of Harbin Medical University
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Application filed by Tianjin Hengyu Medical Technology Co ltd, 2nd Affiliated Hospital Of Harbin Medical University filed Critical Tianjin Hengyu Medical Technology Co ltd
Priority to CN201611203292.4A priority Critical patent/CN106691380A/en
Publication of CN106691380A publication Critical patent/CN106691380A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062Arrangements for scanning
    • A61B5/0066Optical coherence imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0233Special features of optical sensors or probes classified in A61B5/00
    • A61B2562/0238Optical sensor arrangements for performing transmission measurements on body tissue

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Endoscopes (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

The invention discloses an OCT probe used for optical path automatic calibration. The OCT probe used for optical path automatic calibration comprises a grin-lens, one end of the grin-lens is provided with a refraction lens, the other end of the grin-lens is provided with a single-mode optical fiber, the side, far away from the refraction lens, of the refraction lens is provided with a sealing cap, the outside of the single-mode optical fiber is provided with a torque cable, the outsides of the grin-lens and the refraction lens are provided with high scattering rate heat shrink tubes, and the outsides of the high scattering rate heat shrink tubes are provided with protection sleeves. The high scattering rate heat shrink tubes are made of a heat shrinkable material PET, a small amount of optical scattering particles are doped in the PET material, the back scattering rate can be increased, thus the high scattering rate heat shrink tubes form a largest detectable peak of an image strength in an image signal, and the positions of a reference arm and a sample arm zero optical path difference can be easily identified. According to the OCT probe used for optical path automatic calibration, the mechanical strength of the OCT probe is improved, and the possibility that the OCT probe is used for a complex, narrow and curved diseased region is increased.

Description

A kind of OCT probe calibrated automatically for light path
Technical field
The invention belongs to OCT probe technical field, and in particular to a kind of OCT probe calibrated automatically for light path.
Background technology
Optical coherence tomography(Optical Coherence Tomography, abbreviation OCT)Technology is a kind of new Biomedical optical imaging mode, the technology high resolution(5-10 μm of axial resolution, 20-40 μm of lateral resolution), into As speed is fast, signal to noise ratio is high, therefore become a focus in medical imaging field rapidly.Endoscopic optical coherent fault imaging skill Art needs equipment and conduit to coordinate in order, can just carry out corresponding imaging operation, obtains correct, clearly image.In order to obtain Interference signal, it is ensured that the sample arm and reference arm light path of optical interferometric devices are roughly equal.Due to the catheter length of sample arm Can be slightly different, therefore, realize that light path regulatory function is necessary in the reference arm of optical interferometric devices.
Light path is adjusted, and generally by manual control host computer, is progressively sent and is ordered and visually observe screen picture, when reaching Positioned to host computer is operated during correct position.This method has several defects:Visually observe and there are subjective differences, by Result may be caused to be inaccurate;Often changing a conduit will waste time and energy to reference arm manual adjustment once;Use preceding need Could be proper use of after wanting professional to give operating personnel training, increase the Operating Complexity of equipment, clinical practice is suitable Inconvenience.
The probe processing mode for using at present in addition mainly has following two types:One be by gluing mode, due to Single-mode fiber is possible to different from the external diameter of GRIN Lens and turning lens, so the mode of gluing is not ensured that preferably Mechanical performance, probe is possible to fracture or damages during by diseased region;The mechanical performance of probe also has relation with dispensing amount, but It is that dispensing amount can not be too many, can otherwise influences the optical property of lens.Another kind probe be by single-mode fiber, self-focusing optical fiber and Coreless fiber is cut and is made by fused fiber splice and length, and this processing mode is very fragile at fusion point, mechanical strength It is not high.So current OCT probe generally existing mechanical strength problem not high, need careful in use, such as run into complexity Lesion, can only abandon imaging.
But the not only complex structure of OCT probe in the market, and unitary function, need professional to intervene and adjust manually Whole, the use difficulty of system is high, reduces system accuracies.
The content of the invention
It is an object of the invention to provide a kind of OCT probe calibrated automatically for light path, to solve above-mentioned background technology The professional's intervention that needs of middle proposition is manually adjusted, and the use difficulty of system is high, reduces the problem of system accuracies.
To achieve the above object, the present invention provides following technical scheme:A kind of OCT probe calibrated automatically for light path, Including GRIN Lens, one end of the GRIN Lens is provided with turning lens, and the other end is provided with single-mode fiber, described turn Folding lens are provided with seal cap away from the side of GRIN Lens, and the outside of the single-mode fiber is provided with moment of torsion cable, described GRIN Lens is provided with scattered power heat-shrink tube high with the outside of turning lens, and the outside of the scattered power heat-shrink tube high is provided with Protection sleeve pipe.
Preferably, the single-mode fiber is fixedly connected with GRIN Lens by adhesive.
Preferably, the GRIN Lens is fixedly connected with turning lens by adhesive.
Preferably, the single-mode fiber, GRIN Lens are fixedly connected with turning lens by scattered power heat-shrink tube high.
Preferably, the turning lens are used for beam direction of transferring, and can cut into spy by coreless fiber, glass lens etc. Determine angle to be made, it is also possible to realized by plating reflective film in lens surface.
The present invention compared with prior art, has the advantages that:Scattered power heat-shrink tube high during this is practical is by warm Compression material PET is made, and PET has good biocompatibility, is widely used in medical treatment device, is adulterated in PET material few The optical scatter of amount, can improve backscattering rate so that scattered power heat-shrink tube high forms an image in picture signal The maximum detectable peak of intensity, with reference to specific algorithm, can easily identify the position of reference arm and sample arm zero optical path difference, Then control system is fed back to, control system controlled motor again, the light path for adjusting reference arm is matched with sample arm, so that a key reality Existing light path positioning, eliminates the shortcoming of artificial calibration, and the present invention improves the mechanical strength of OCT probe, increased it and be applied to Complicated, narrow, bending diseased region possibility.
Brief description of the drawings
Fig. 1 is structural representation of the invention;
In figure:1- single-mode fibers, 2- GRIN Lens, 3- turning lens, 4- scattered power heat-shrink tube high, 5- moments of torsion cable, 6- are close Sealing cap, 7- protection sleeve pipes.
Specific embodiment
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is carried out clear, complete Site preparation is described, it is clear that described embodiment is only a part of embodiment of the invention, rather than whole embodiments.It is based on Embodiment in the present invention, it is every other that those of ordinary skill in the art are obtained under the premise of creative work is not made Embodiment, belongs to the scope of protection of the invention.
Fig. 1 is referred to, the present invention provides a kind of technical scheme:A kind of OCT probe calibrated automatically for light path, including from Condenser lens 2, one end of GRIN Lens 2 is provided with turning lens 3, and the other end is provided with single-mode fiber 1, and turning lens 3 are remote The side of GRIN Lens 2 is provided with seal cap 6, the outside of single-mode fiber 1 is provided with moment of torsion cable 5, GRIN Lens 2 with The outside of turning lens 3 is provided with scattered power heat-shrink tube 4 high, and the outside of scattered power heat-shrink tube 4 high is provided with protection sleeve pipe 7.
In the present embodiment, it is preferred that single-mode fiber 1 is fixedly connected with GRIN Lens 2 by adhesive, adhesive is light Learn glue glued, single-mode fiber 1 can also be linked together with GRIN Lens 2 by the technology of welding.
In the present embodiment, it is preferred that GRIN Lens 2 is fixedly connected with turning lens 3 by adhesive, adhesive is Optical glue is glued, and GRIN Lens 2 can also be linked together with turning lens 3 by the technology of welding.
In the present embodiment, it is preferred that single-mode fiber 1, GRIN Lens 2 and turning lens 3 are by scattered power pyrocondensation high Pipe 4 is fixedly connected, and scattered power heat-shrink tube 4 high uses transparent material contracting with heat, such as polyester(PET), the specially treated is main Refer to the method for improving the heat-shrink tube backscattering rate, including but not limited to plate a floor height scattered power film, mixed in heat-shrink tube The particle of miscellaneous microsize.
In the present embodiment, it is preferred that turning lens are used for beam direction of transferring, can be by coreless fiber, glass lens etc. Cut into special angle to be made, it is also possible to realized by plating reflective film in lens surface.
Scattered power heat-shrink tube 4 high in the present invention has the specific function that heat is shunk, and more than 98 DEG C of heating is i.e. collapsible, It is easy to use.For electrolytic capacitor, inductance, product resistance to elevated temperatures is good, without secondary contraction, can be on behalf of printing.For various The monomer of rechargeable battery, assembly packaging, and on behalf of design, print pattern, and can be cut for visitor.For various curtain rods, shower curtain The outer cladding of the tubular articles such as bar, peg, mop rod, broomstick, tool bar, expansion link, garden instrument, strut.And can be used for Bus bar copper row, joint, the mark of wire harness, insulation outer cladding in low-pressure chamber.Efficiency high, equipment investment are few, integrated cost is small.With It is the packaging material of a new generation in lamp decoration, the cladding of LED pins, and guitar, the parcel of packaging bottleneck.It is either civilian, automobile-used Or it is military, all it is upper choosing.
Operation principle of the invention and use flow:When being used, staff is checked the present invention first, Defect is checked for, if there is cannot just carry out using if defect, now needs to notify that maintenance personal is tieed up Repairing, if there is no can be carried out using if problem, single-mode fiber 1, GRIN Lens 2 and turning lens 3 being used into optics Glue is bonded together, and single-mode fiber 1 is located in hollow moment of torsion cable 5, and the moment of torsion that moment of torsion cable 5 produces OCT systems is passed Probe is delivered to, allows probe rotary motion and translational motion in sleeve pipe 7 is protected, during processing, first by single-mode fiber 1, autohemagglutination Focus lens 2 and turning lens 3 are bonding, then take one small section high scattered power heat-shrink tube 4, carefully pass through turning lens from one end 3rd, GRIN Lens 2 and single-mode fiber 1, noting this one end of scattered power heat-shrink tube 4 high will be to 3cm through after moment of torsion cable 52 Only, can so strengthen the intensity between the port of moment of torsion cable 5 and single-mode fiber 1, then take an external diameter and be slightly less than high dissipating The metal core axle of the internal diameter of rate heat-shrink tube 4 is penetrated, metal core axle is penetrated from the other end of heat-shrink tube 4, until metal core axle just connects The tip of turning lens 3 is touched, heat-shrink tube 4 is welded at leisure toward two ends from middle under hot-air welding machine, it is ensured that the jail of heat-shrink tube 4 Moment of torsion cable 5 and lens surface are attached to firmly, metal core axle is extracted out, and blade is used at away from the tip of turning lens 3 about 2 to 3cm Unnecessary heat-shrink tube is cut away, then a seal cap 6 is formed, by pyrocondensation in blade incision with minimal amount of optical cement water spot Pipe 4 is closed, and protection sleeve pipe 7 is finally carefully penetrated again, that is, process a kind of OCT probe calibrated automatically for light path.
Although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with Understanding can carry out various changes, modification, replacement to these embodiments without departing from the principles and spirit of the present invention And modification, the scope of the present invention be defined by the appended.

Claims (5)

1. a kind of OCT probe calibrated automatically for light path, including GRIN Lens(2), it is characterised in that:The self-focusing is saturating Mirror(2)One end be provided with turning lens(3), the other end is provided with single-mode fiber(1), the turning lens(3)Away from autohemagglutination Focus lens(2)Side be provided with seal cap(6), the single-mode fiber(1)Outside be provided with moment of torsion cable(5), it is described from Condenser lens(2)With turning lens(3)Outside be provided with scattered power heat-shrink tube high(4), the scattered power heat-shrink tube high(4)'s Outside is provided with protection sleeve pipe(7).
2. a kind of OCT probe calibrated automatically for light path according to claim 1, it is characterised in that:The single-mode optics It is fine(1)With GRIN Lens(2)It is fixedly connected by adhesive.
3. a kind of OCT probe calibrated automatically for light path according to claim 1, it is characterised in that:The self-focusing Lens(2)With turning lens(3)It is fixedly connected by adhesive.
4. a kind of OCT probe calibrated automatically for light path according to claim 1, it is characterised in that:The single-mode optics It is fine(1), GRIN Lens(2)And turning lens(3)By scattered power heat-shrink tube high(4)It is fixedly connected.
5. a kind of OCT probe calibrated automatically for light path according to claim 1, it is characterised in that:The turnover is saturating Mirror(3)For beam direction of transferring, special angle can be cut into by coreless fiber, glass lens etc. and be made, it is also possible to passed through Realized in lens surface plating reflective film.
CN201611203292.4A 2016-12-23 2016-12-23 OCT probe used for optical path automatic calibration Pending CN106691380A (en)

Priority Applications (1)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112014354A (en) * 2020-09-09 2020-12-01 佛山光微科技有限公司 OCT reference arm optical path determination and adjustment method and device, storage medium and terminal
CN113237850A (en) * 2021-04-29 2021-08-10 广州永士达医疗科技有限责任公司 Optical fiber collimator for OCT (optical coherence tomography), manufacturing method and OCT equipment
CN113909071A (en) * 2021-10-08 2022-01-11 南京沃福曼医疗科技有限公司 Packaging method of OCT imaging probe
CN117146700A (en) * 2023-10-30 2023-12-01 天津恒宇医疗科技有限公司 OCT equipment optical path calibration method and device and OCT equipment

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CN101854850A (en) * 2007-11-12 2010-10-06 光学实验室成像公司 Imaging catheter with integrated reference reflector
US20160313507A1 (en) * 2007-11-12 2016-10-27 Lightlab Imaging, Inc. Miniature Optical Elements for Fiber-Optic Beam Shaping
CN105228514A (en) * 2013-03-15 2016-01-06 阿维格公司 Optical pressure sensor assembly
US20160227990A1 (en) * 2013-09-17 2016-08-11 The Johns Hopkins University Device and methods for color corrected oct imaging endoscope/catheter to achieve high-resolution
CN103767660A (en) * 2014-02-20 2014-05-07 上海交通大学 Endoscope
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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112014354A (en) * 2020-09-09 2020-12-01 佛山光微科技有限公司 OCT reference arm optical path determination and adjustment method and device, storage medium and terminal
CN113237850A (en) * 2021-04-29 2021-08-10 广州永士达医疗科技有限责任公司 Optical fiber collimator for OCT (optical coherence tomography), manufacturing method and OCT equipment
CN113909071A (en) * 2021-10-08 2022-01-11 南京沃福曼医疗科技有限公司 Packaging method of OCT imaging probe
CN117146700A (en) * 2023-10-30 2023-12-01 天津恒宇医疗科技有限公司 OCT equipment optical path calibration method and device and OCT equipment
CN117146700B (en) * 2023-10-30 2024-01-30 天津恒宇医疗科技有限公司 OCT equipment optical path calibration method and device and OCT equipment

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