CN106674744A - Polypropylene aseptic composite material for outer cylinder of medical syringe - Google Patents
Polypropylene aseptic composite material for outer cylinder of medical syringe Download PDFInfo
- Publication number
- CN106674744A CN106674744A CN201611216900.5A CN201611216900A CN106674744A CN 106674744 A CN106674744 A CN 106674744A CN 201611216900 A CN201611216900 A CN 201611216900A CN 106674744 A CN106674744 A CN 106674744A
- Authority
- CN
- China
- Prior art keywords
- polypropylene
- hopp
- added
- medical syringe
- composite material
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L23/00—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
- C08L23/02—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers not modified by chemical after-treatment
- C08L23/10—Homopolymers or copolymers of propene
- C08L23/12—Polypropene
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K2201/00—Specific properties of additives
- C08K2201/011—Nanostructured additives
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2201/00—Properties
- C08L2201/10—Transparent films; Clear coatings; Transparent materials
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2203/00—Applications
- C08L2203/02—Applications for biomedical use
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2205/00—Polymer mixtures characterised by other features
- C08L2205/03—Polymer mixtures characterised by other features containing three or more polymers in a blend
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2205/00—Polymer mixtures characterised by other features
- C08L2205/24—Crystallisation aids
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Materials For Medical Uses (AREA)
Abstract
The invention relates to a polypropylene aseptic composite material for an outer cylinder of a medical syringe. The polypropylene aseptic composite material is prepared from the following raw materials in parts by weight: 50 to 100 parts of homo-polypropylene, 0.1 to 0.5 part of nucleating agent, 0.1 to 0.5 part of crystallization promoter, 0.1 to 0.3 part of antioxidant, 0.1 to 0.3 part of nano silica, 0.05 to 0.1 part of crospovidone and 0.05 to 0.1 part of cetanol. In comparison with the prior art, the keys of the application are that suitable functional aids of the nucleating agent, a crystallizing agent, a stabilizing agent and the like are selected; the homo-polypropylene is used as a main material; the nucleating agent is added, so that a polymer can be subjected to heterogeneous nucleation; the rigidity, the abrasion resistance and the processability of the material are meliorated; the crystallization promoter is added to improve the crystallinity and the crystallization rate of the material and to decrease the grain size of the material; the nano silica is added to improve the transparency and the strength of the material; the turbidity of a sheet of which the thickness is 1.3 can reach below 8 percent; the crospovidone and the cetanol are added to play complexing, stabilizing and thickening roles; the composite material stable in performance can be obtained; the standard of a material for a medical-purpose syringe is quite well met.
Description
Technical field
The present invention relates to technical field of polymer materials, and in particular to a kind of medical syringe outer barrel is multiple with polypropylene sterile
Condensation material.
Background technology
Plastic injector compared with traditional glass syringe, with it is nontoxic, aseptic, without pyrogen, can prevent sterilization not
The good cross-infection for causing and it is easy to operate the advantages of, and be widely used in medical field.Current ordinary syringe profile is divided into
Two-piece and three-member type, two-piece save rubber piston part, only syringe jacket and core with respect to three-member type in composition
Bar is constituted.For the use requirement of syringe, its lagging material must have the excellent transparency to ensure milli reading with no difficulty
Scale value is taken, while there is sufficiently low frictional resistance between overcoat and core bar surface, to ensure being smoothed out for injection.
Traditional syringe outer barrel stability of material is bad, and lubricity is not also high.
The content of the invention
The technical problems to be solved by the invention are to improve a kind of using safety, outside the bubble-tight medical syringe of inwall
Cylinder uses polypropylene sterile composite.
The technical problems to be solved by the invention are realized using following technical scheme：
A kind of medical syringe outer barrel polypropylene sterile composite, including following parts by weight raw material：
Described nucleator is monocyclic carboxylate nucleator, specially benzoic acid sodium salt, benzoic acid aluminium salt, diphenyl acetic acid
The mixture of one or more in sodium salt or hexahydro-phthalic acid.
Described crystallization promoter selects polyethylene glycol.
The preparation method of above-mentioned composite is：By HOPP and nucleator, crystallization promoter, antioxidant, receive
After rice silica, PVPP and cetanol are well mixed, it is added in double screw extruder, kneads, extrusion, cooling,
Dry, granulation obtains polypropylene sterile composite.
Above-mentioned HOPP is processed by static elimination, and specific static elimination processing method is as follows：
(1) graininess HOPP feeding degausser is carried out into demagnetization treatment, by three demagnetizations, removes homopolymerization poly- third
The magnetic of alkene, then unified collection；
Degausser carries out demagnetization using strong magnetic roller degausser, PP GRANULES was descended from strong magnetic roller, passes through
Demagnetization is processed, and product is not produced electrostatic, is easy to the application of product；
(2) by weight 85:The ratio of 5-10 weighs the HOPP and plasticizer after demagnetization, by HOPP and
Plasticizer is put into mixer, and mixer temperature setting is 80 DEG C~84 DEG C, is mixed 20 minutes, is sufficiently mixed two kinds of material,
Then double screw extruder extruding pelletization is put into, master batch material is obtained；Two kinds of material are made to fuse into one by granulation, beneficial to following process
Treatment；
(3) carry out primary crystallization drying again to master batch material, collect dried object and be the HOPP material for eliminating electrostatic.
Compared with prior art, it is critical only that for the application have selected the functions such as suitable nucleator, crystallizing agent, stabilizer
Auxiliary agent, using HOPP as major ingredient, adds nucleator to make polymer heterogeneous nucleation, improves rigidity, the wearability of material
And processing characteristics；Add crystallization promoter to improve the crystallinity and crystalline rate of material, its crystallite dimension is reduced, in injection process
Inwall is non-foaming；Nano silicon is added to improve the transparency and intensity of material, thickness is that 1.3 sheet material turbidity can reach
Less than 8%；Add PVPP and cetanol to play complexing, stabilization and thickening power, can obtain the composite of stable performance,
The standard of injector for medical purpose material is met well.
The beneficial effects of the invention are as follows：PP composite material of the invention, takes the raw material that can be applied to medical field,
Properties meet《Medical infusion, blood transfusion, syringe polypropylene dedicated material》National standard, have compared with prior art
Clear advantage.
Specific embodiment
In order that technological means, creation characteristic, reached purpose and effect that the present invention is realized are easy to understand, tie below
Specific embodiment is closed, the present invention is expanded on further.
Embodiment 1
By the nucleator of the HOPP of 100 weight portions and 0.5 weight portion, the crystallization promoter of 0.5 weight portion, 0.3
The whale of the antioxidant of weight portion, the nano silicon of 0.3 weight portion, the PVPP of 0.1 weight portion and 0.1 weight portion
After ceryl alcohol is well mixed, it is added in double screw extruder, kneads, extrusion, cooling is dried, granulation, obtains polypropylene sterile and answer
Condensation material.
Embodiment 2
By the nucleator of the HOPP of 100 weight portions and 0.1 weight portion, the crystallization promoter of 0.1 weight portion, 0.1
The antioxidant of weight portion, the nano silicon of 0.1 weight portion, the PVPP of 0.05 weight portion and 0.05 weight portion
After cetanol is well mixed, it is added in double screw extruder, kneads, extrusion, cooling is dried, granulation obtains polypropylene sterile
Composite.
Embodiment 3
By the nucleator of the HOPP of 100 weight portions and 0.4 weight portion, the crystallization promoter of 0.4 weight portion, 0.2
The antioxidant of weight portion, the nano silicon of 0.2 weight portion, the PVPP of 0.08 weight portion and 0.08 weight portion
After cetanol is well mixed, it is added in double screw extruder, kneads, extrusion, cooling is dried, granulation obtains polypropylene sterile
Composite.
Embodiment 4
By the nucleator of the HOPP of 100 weight portions and 0.3 weight portion, the crystallization promoter of 0.3 weight portion, 0.25
The antioxidant of weight portion, the nano silicon of 0.25 weight portion, the PVPP of 0.07 weight portion and 0.06 weight portion
Cetanol it is well mixed after, be added in double screw extruder, knead, extrusion, cooling is dried, granulation, obtain polypropylene without
Bacterium composite.
Embodiment 5
By the nucleator of the HOPP of 50 weight portions and 0.5 weight portion, the crystallization promoter of 0.5 weight portion, 0.3 weight
Measure the spermaceti of the antioxidant, the nano silicon of 0.3 weight portion, the PVPP of 0.1 weight portion and 0.1 weight portion of part
After alcohol is well mixed, it is added in double screw extruder, kneads, extrusion, cooling is dried, granulation, obtains polypropylene sterile and be combined
Material.
Tensile strength, bending modulus, turbidity, confficient of static friction and dynamic friction system to gained polypropylene sterile composite
Number is tested, and the results are shown in Table 1.
Table 1
The composite prepared to embodiment 1, carries out chemical property and biological property detection, as a result as shown in table 2.
Table 2
General principle of the invention and principal character and advantages of the present invention has been shown and described above.The technology of the industry
Personnel it should be appreciated that the present invention is not limited to the above embodiments, simply explanation described in above-described embodiment and specification this
The principle of invention, without departing from the spirit and scope of the present invention, various changes and modifications of the present invention are possible, these changes
Change and improvement all fall within the protetion scope of the claimed invention.The claimed scope of the invention by appending claims and its
Equivalent thereof.
Claims (5)
1. a kind of medical syringe outer barrel polypropylene sterile composite, it is characterised in that by the raw material system of following parts by weight
Into：
2. medical syringe outer barrel polypropylene sterile composite according to claim 1, it is characterised in that described
Nucleator is monocyclic carboxylate nucleator, and specially benzoic acid sodium salt, benzoic acid aluminium salt, diphenyl acetic acid sodium salt or hexahydro is adjacent
The mixture of one or more in phthalic acid.
3. medical syringe outer barrel polypropylene sterile composite according to claim 1, it is characterised in that described
Crystallization promoter selects polyethylene glycol.
4. medical syringe outer barrel polypropylene sterile composite according to claim 1, it is characterised in that it is above-mentioned
Poly- polypropylene is processed by static elimination, and specific static elimination processing method is as follows：
(1) graininess HOPP feeding degausser is carried out into demagnetization treatment, by three demagnetizations, removal HOPP
Magnetic, then unified collection；
(2) by weight 85:The ratio of 5-10 weighs the HOPP and plasticizer after demagnetization, by HOPP and plasticising
Agent is put into mixer, and mixer temperature setting is 80 DEG C~84 DEG C, is mixed 20 minutes, is sufficiently mixed two kinds of material, then
Input double screw extruder extruding pelletization, obtains master batch material；Two kinds of material are made to fuse into one by granulation, at following process
Reason；
(3) carry out primary crystallization drying again to master batch material, collect dried object and be the HOPP material for eliminating electrostatic.
5. a kind of method for preparing composite described in claim any one of 1-4, it is characterised in that：By HOPP and into
After core agent, crystallization promoter, antioxidant, nano silicon, PVPP and cetanol are well mixed, double spiral shells are added to
In bar extruder, mixing, extrusion, cooling is dried, and granulation obtains polypropylene sterile composite.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611216900.5A CN106674744A (en) | 2016-12-26 | 2016-12-26 | Polypropylene aseptic composite material for outer cylinder of medical syringe |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611216900.5A CN106674744A (en) | 2016-12-26 | 2016-12-26 | Polypropylene aseptic composite material for outer cylinder of medical syringe |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106674744A true CN106674744A (en) | 2017-05-17 |
Family
ID=58871421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611216900.5A Pending CN106674744A (en) | 2016-12-26 | 2016-12-26 | Polypropylene aseptic composite material for outer cylinder of medical syringe |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106674744A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101696302A (en) * | 2009-10-29 | 2010-04-21 | 广州市合诚化学有限公司 | Self-lubricating polypropylene compound material for manufacturing medical injectors |
| CN105647007A (en) * | 2016-01-19 | 2016-06-08 | 宿州学院 | Environment-friendly high polymer plastic film and preparation method thereof |
| CN105949616A (en) * | 2016-05-30 | 2016-09-21 | 江苏新昌汽车部件有限公司 | Dashboard made from low-odor scraping-resistant polypropylene material |
-
2016
- 2016-12-26 CN CN201611216900.5A patent/CN106674744A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101696302A (en) * | 2009-10-29 | 2010-04-21 | 广州市合诚化学有限公司 | Self-lubricating polypropylene compound material for manufacturing medical injectors |
| CN105647007A (en) * | 2016-01-19 | 2016-06-08 | 宿州学院 | Environment-friendly high polymer plastic film and preparation method thereof |
| CN105949616A (en) * | 2016-05-30 | 2016-09-21 | 江苏新昌汽车部件有限公司 | Dashboard made from low-odor scraping-resistant polypropylene material |
Non-Patent Citations (3)
| Title |
|---|
| 方亮等: "《药用高分子材料学》", 31 August 2015, 中国医药科技出版社 * |
| 曾攀: "《塑性非线性分析原理》", 30 September 2015, 机械工业出版社 * |
| 杨始堃: "《聚酯合金技术与应用》", 31 January 2010, 机械工业出版社 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR101855054B1 (en) | Composition based on poly (arylene ether ketone) having improved properties | |
| CN103554624B (en) | The preparation method of antibacterial polyvinyl resin | |
| CN105504552B (en) | A kind of tubing material of polybutene 1 and preparation method thereof | |
| JP3358659B2 (en) | Diacetal composition, nucleating agent for polyolefin containing the composition, polyolefin resin composition containing the diacetal composition, method for producing the resin composition, and molded article | |
| MX362113B (en) | Melt-extruded solid dispersions containing an apoptosis-inducing agent. | |
| CN105237903B (en) | A kind of transparent medical PVC material for being applied to wide ripple lucifuge and preparation method thereof | |
| CN107540920B (en) | Metallocene polyethylene composition and preparation method thereof | |
| CN103724950B (en) | A kind of composition and method of making the same and PBAT preservative film containing PBAT | |
| CN107652641A (en) | Low-cost bio based fully degradable high transmittance film and preparation method thereof | |
| Williams et al. | Hot-melt extrusion technology: optimizing drug delivery | |
| CN107043480A (en) | Capacitor insulation shield material and preparation method thereof | |
| CN105907063A (en) | Antibacterial biological nano packaging film and preparation method thereof | |
| JP7000348B2 (en) | Use of amino sugars as plasticizers | |
| CN112250974A (en) | Special material for transparent polyvinylidene fluoride weather-resistant antibacterial film and preparation method thereof | |
| CN108192188A (en) | A kind of degradable polyethylene packaging film and preparation method thereof | |
| CN104725732B (en) | Low-hardness medical thermoplastic brominated butyl rubber and preparation method thereof | |
| US20050238721A1 (en) | One step compounding extrusion of drug filled polymers | |
| CN106674744A (en) | Polypropylene aseptic composite material for outer cylinder of medical syringe | |
| CN103735512A (en) | Enrofloxacin solid dispersion and preparation method thereof | |
| CN113429635A (en) | High-starch-content film-grade full-biodegradable masterbatch and preparation method thereof | |
| CN104962002A (en) | Preparation method for polyvinyl chloride material for medical mask | |
| CN105086236B (en) | A kind of RPVC（U‑PVC）Plastics and its pipe fitting and preparation method | |
| CN115785609A (en) | Transparent ABS resin composition and preparation method and application thereof | |
| CN105175939B (en) | High-oxygen-permeability medical PVC (polyvinyl chloride) material and preparation method of high-oxygen-permeability medical PVC material | |
| CN104497415A (en) | Thermoplastic elastomer for transfusion bag and preparation method of thermoplastic elastomer for transfusion bag |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170517 |