CN106668462A - Traditional Chinese medicine composition for treatment of breast cancer and preparation method thereof - Google Patents

Abstract

The invention belongs to the technical field of traditional Chinese medicine preparations, and aims at providing a traditional Chinese medicine composition for treatment of breast cancer based on cognition mechanism on the breast cancer in traditional Chinese medicine. The traditional Chinese medicine composition comprises the following components in parts by mass: 80-180g of rhizoma cyperi, 80-180g of Chinese angelica, 30-120g of fritillary bulb, 30-120g of radix bupleuri, 60-120g of radix paeoniae rubra, 50-150g of radix paeoniae alba, 30-120g of tangerine peel, 60-120g of cowherb seed, 50-120g of pangolin scales, 90-160g of fructus trichosanthis, 90-350g of radix astragali seu hedysari, 150-480g of rhizoma polygoni cuspidati, 150-350g of honeysuckle flower, 30-70g of chinese gentian, 150-300g of fructus forsythiae, 30-100g of rhizoma chuanxiong, 150-350g of herba hedyotidis diffusae and 50-160g of radix angelicae. The medicine disclosed by the invention is a traditional Chinese medicine formula which can resolve the current problems and eliminate the root causes.

Description

A kind of Chinese medicine composition and preparation method for treating breast carcinoma

Technical field

The invention belongs to field of traditional Chinese, and in particular to a kind of Chinese medicine composition for treating breast carcinoma, particularly The Chinese medicine composition used for patient with breast cancer and the field of preparation method.

Background technology

Motherland's medical science thinks：Female mammary gland is made up of skin, fibrous tissue, corpus mamma and fat, and breast carcinoma is There is the malignant tumor in mammary gland glandular epithelium tissue.99% occurs in women in breast carcinoma, and male only accounts for 1%.

Mammary gland is not the vitals for maintaining human life activity, and breast cancer in situ is not fatal；But due to breast carcinoma The cell loss characteristic of normal cell, connects loose between cell, easily come off.Cancerous cell once comes off, and free cancer is thin Born of the same parents can send out whole body with blood or lymph fluid, form transfer, threat to life.At present breast carcinoma becomes threat women body and mind and is good for The kinds of tumor of health.

Global breast cancer incidence starts in rising trend always from late 1970s.8, U.S. women is in life Just have 1 people to suffer from breast cancer.China is not the country occurred frequently of breast carcinoma, but unsuitable optimistic, in recent years China's breast cancer incidence Growth rate is but higher by national 1~2 percentage point occurred frequently.According to National Cancer Center and Ministry of Public Health prevention and control of diseases office 2012 The pathogenesis of breast carcinoma data in 2009 announced show：National tumour registration area breast cancer incidence occupies female malignant 1st, female mammary gland cancer morbidity（It is rough and careless）The whole nation adds up to 42.55/10 ten thousand, and city is 51.91/10 ten thousand, and rural area is 23.12/10 ten thousand.

Breast carcinoma has become the great public health problem of current social.From the nineties in 20th century, global breast cancer deaths Rate presents downward trend；Trace it to its cause, one is the development of breast carcinoma screening, making the ratio of early-stage cases increases；Two are The development of comprehensive therapy of breast cancer, improves curative effect.Breast carcinoma has become one of optimal entity tumor of curative effect.

So, with regard to how to find it is a kind of can the above-mentioned breast carcinoma of effectively treatment medicine, be those skilled in the art urgently will The problem of solution.

The content of the invention

With the continuous development of China's Chinese medicine, in treatment breast carcinoma, people gradually appreciate Chinese traditional treatment The advantage of breast carcinoma, and the advantage such as over the course for the treatment of good effect, instant effect, toxic and side effects are little, for existing western medical treatment breast The present situation of adenocarcinoma, it is to provide a kind of Chinese medicine composition for treating breast carcinoma that the purpose of the present invention is, to solve breast carcinoma Patient's restorative problem early.The medicine is with common Chinese medicine as raw material, by selecting rational medicine and mass parts Than can the above-mentioned breast carcinoma of effectively treatment.

To reach the purpose of foregoing invention, the technical solution adopted in the present invention is：There is provided a kind of for treating breast carcinoma Chinese medicine composition and preparation method, it is characterised in that each component and its mass parts of the Chinese medicine composition is than following institute Show：

80~180g of Rhizoma Cyperi, 80~180g of Radix Angelicae Sinensis, 30~120g of Bulbus Fritillariae Thunbergii, 30~120g of Radix Bupleuri, 60~120g of Radix Paeoniae Rubra, the Radix Paeoniae Alba 50 ~150g, 30~120g of Pericarpium Citri Reticulatae, 60~120g of Semen Vaccariae, 50~120g of roasted SQUAMA MANITIS into puffy with sand, 90~160g of Fructus Trichosanthis, the Radix Astragali 90~ 350g, 150~480g of Rhizoma Polygoni Cuspidati, 150~350g of Flos Lonicerae, 30~70g of Radix Gentianae, 150~300g of Fructus Forsythiae, 30~100g of Rhizoma Chuanxiong, 150~350g of Herba Hedyotidis Diffusae, 50~160g of the Radix Angelicae Dahuricae.

A kind of Chinese medicine composition and preparation method for treating breast carcinoma, it is characterised in that the Chinese medicine composition Each component and its mass parts are than as follows：

90~160g of Rhizoma Cyperi, 90~160g of Radix Angelicae Sinensis, 40~105g of Bulbus Fritillariae Thunbergii, 40~105g of Radix Bupleuri, 70~105g of Radix Paeoniae Rubra, the Radix Paeoniae Alba 60 ~130g, 40~105g of Pericarpium Citri Reticulatae, 70~105g of Semen Vaccariae, 60~105g of roasted SQUAMA MANITIS into puffy with sand, 100~140g of Fructus Trichosanthis, the Radix Astragali 100~ It is 310g, 170~420g of Rhizoma Polygoni Cuspidati, 170~310g of Flos Lonicerae, 40~60g of Radix Gentianae, 170~260g of Fructus Forsythiae, 40~90g of Rhizoma Chuanxiong, white Serpentis 170~310g of SHECAO, 60~140g of the Radix Angelicae Dahuricae.

A kind of Chinese medicine composition and preparation method for treating breast carcinoma, it is characterised in that " preferred plan " Each component of Chinese medicine composition and its mass parts are than as follows：

Rhizoma Cyperi 140g, Radix Angelicae Sinensis 140g, Bulbus Fritillariae Thunbergii 95g, Radix Bupleuri 95g, Radix Paeoniae Rubra 95g, Radix Paeoniae Alba 115g, Pericarpium Citri Reticulatae 95g, Semen Vaccariae 95g, It is roasted SQUAMA MANITIS into puffy with sand 95g, Fructus Trichosanthis 120g, Radix Astragali 280g, Rhizoma Polygoni Cuspidati 380g, Flos Lonicerae 280g, Radix Gentianae 50g, Fructus Forsythiae 230g, Rhizoma Chuanxiong 80g, white Serpentis SHECAO 280g, Radix Angelicae Dahuricae 120g.

A kind of Chinese medicine composition and preparation method for treating breast carcinoma, it is characterised in that methods described includes as follows Step is prepared from：

A, above-mentioned raw materials Chinese medicine is picked after impurity, dust and drying, be ground into superfine end according to mass parts ratio stand-by；

B, the method that Chinese medicine capsules are prepared according to tradition, after ground superfine myrrh thing is sieved, are put in medicine device and mix Uniformly, then it is prepared into capsule（Total length after its capsule is sealed be 23.3mm, medicated powder capacity 0.4~0.5g/ grains）, and then Sealed packaging.

A kind of Chinese medicine composition and preparation method for treating breast carcinoma, it is characterised in that the instructions of taking is：Will The capsule medicine for preparing is serviced once sooner or later with twice a day taking, and 2.5g is administered（5）/ time, warm water delivery service, one It is within individual month a course for the treatment of, after taking medicine 1~2 day, symptom gradually mitigates or fully recovers.

Each raw material Chinese medicine in prescription of the present invention has detailed note in Chinese Pharmacopoeia, Chinese dictionary and China's book on Chinese herbal medicine Carry.The present invention is raw material from most common of which Chinese medicine, gives full play to the pharmacological effect of each component：

Rhizoma Cyperi, nature and flavor：Acrid in the mouth, be slightly cold, it is nontoxic, with Regulate the flow of vital energy Xie Yu, menstruction regulating and pain relieving, it is antiabortive the effect of, it is swollen for treating side of body rib Bitterly, breast swelling, hernia pain, menoxenia, gastral cavity abdomen ruffian is full pain, belch acid regurgitation, vomiting and nausea, abdominal pain during menstruation, bleeding not during menses, tire Dynamic uneasiness, stagnation of QI due to depression of the liver, dyspepsia, amenorrhea dysmenorrhea；

Radix Angelicae Sinensis, nature and flavor：Warm in nature, sweet in the mouth is pungent, the effect of with benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize laxation, for treat blood deficiency, Shallow complexion, dizziness palpitaition, blood deficiency have the stagnant menoxenia of the stasis of blood, amenorrhea, dysmenorrhea, deficient cold type stomachache, coronary heart disease heart strand concurrently Bitterly, rheumatic arthralgia, traumatic injury；

Bulbus Fritillariae Thunbergii, nature and flavor：It is bitter in the mouth, cold in nature, the effect of with removing heat-phlegm, sending down the abnormal ascending QI cough-relieving, mass dissipating and swelling eliminating, for treat wind heat or Phlegm-heat cough, lung carbuncle pyemesis, scrofula goiter, sore and toxic；

Radix Bupleuri, nature and flavor：Bitter in the mouth, pungent, cold nature, bring down a fever with inducing sweat, dispersing the stagnated live-QI to relieve the stagnation of QI, rise the effect of lifting yang-energy, outer for treating Sense heating, alternate attack of chill and fever, malaria, hypochondriac pain due to stagnation of liverQI mammary swelling, have a headache dizziness, menoxenia, the proctoptosis of collapse of QI, uterine prolapse, Gastroptosis；

Radix Paeoniae Rubra, nature and flavor：It is bitter, be slightly cold, the effect of with clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, for treat maculae caused by violent heat pathogen, hematemesis and epistaxiss, Discharging fresh blood stool, conjunctival congestion and swelling pain, carbuncle swells sore, amenorrhea, dysmenorrhea, metrorrhagia and leukorrhagia stranguria with turbid discharge, the stagnant hypochondriac pain of the stasis of blood, the accumulation of hernia abdominal mass, injury from falling down；

The Radix Paeoniae Alba, nature and flavor：Bitter, acid, it is slightly cold, with blood-nourishing and the effect of battalion, relieving spasm to stop pain, yin fluid astringing suppressing the hyperactive liver, for treating menstruation not Tune, abdominal pain during menstruation, metrorrhagia, spontaneous perspiration, night sweat, side of body rib epigastric pain, limb pain twin, headache, dizziness；

Pericarpium Citri Reticulatae, nature and flavor：It is acrid in the mouth, hardship, warm in nature, with qi-regulating and in, drying dampness to eliminate phlegm, the effect of diuretic relieving constipation, for treating taste Discord, abdominal distention, anorexia, vomiting hiccup, accumulation of phlegm-damp in the lung, cough with copious phlegm, the chest and diaphragm full vexed, vertigo, edema, urine The diseases such as unfavorable, constipation, acute mastitis scabies, middle ichthyophagy crab poison, alcoholism；

Semen Vaccariae, nature and flavor：It is bitter, mild-natured, the effect of with promoting blood circulation to restore menstrual flow, unable to suck milk eliminating carbuncle, for treating women's abdominal pain during menstruation, Jing Close, the disease such as galactostasiss, acute mastitis, carbuncle；

Roasted SQUAMA MANITIS into puffy with sand, nature and flavor：It is salty, cool, be slightly cold, with stimulating milk secretion of stimulating the menstrual flow, detumescence and apocenosis, search wind and removing obstruction in channels the effect of, for treating amenorrhea WEIJIA, galactostasiss, carbuncle sore tumefacting virus, arthralgia, numbness contracture；

Fructus Trichosanthis, nature and flavor：It is sweet, slight bitter, cold, the effect of with clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturize laxation, cough for treating lung-heat Cough, the thick turbid Huang of expectorant, obstruction of qi in the chest and cardialgia, blocked-up chest feeling of fullness, acute mastitis, lung abscess, acute appendicitis swell and ache, constipation；

The Radix Astragali, nature and flavor：Sweet, temperature, the effect of with invigorating QI to consolidate the body surface resistance, inducing diuresis to remove edema, expelling pus and toxin by strengthening QI, expelling pus and promoting granulation, granulation promoting, for controlling Treat treatment deficiency of vital energy weak, anorexia and loose stool, sinking of QI of middle-JIAO, rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, ulcer is difficult to burst, long Burst do not hold back, flaccidity of limbs due to deficiency of blood is yellow, Heat Diabetes, chronic nephritis proteinuria, diabetes；

Rhizoma Polygoni Cuspidati, nature and flavor：Mildly bitter flavor, slightly cool in nature, the effect of with promoting blood circulation and stopping pain, eliminating damp-heat, relieving cough and resolving phlegm, for treating joint Pain, amenorrhea, jaundice due to damp-heat, chronic tracheitiss, hyperlipemia, outward for burn and scald, injury from falling down, carbuncle sore tumefacting virus；

Flos Lonicerae, nature and flavor：Sweet, the effect of there is heat-clearing and toxic substances removing of trembling with fear, for treating warm disease heating, toxic-heat and blood stasis, carbuncle swells furunculosis, larynx Numbness and multi-infection disease；

Radix Gentianae, nature and flavor：Hardship, tremble with fear, heat clearing and damp drying, eliminating pathogen in the liver gallbladder effect of fire, for treat jaundice due to damp-heat, swelling of the vulva pudendal pruritus, leukorrhagia, Persistent erection of the penis, eczema itch, conjunctival congestion, deafness, hypochondriac pain, bitter taste, convulsion with spasms；

Fructus Forsythiae, nature and flavor：Bitter, cold nature, the effect of with heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, anemopyretic cold, for treating wind heat sense Emit, the disease such as epidemic febrile disease, pyretic stranguria urine retention, carbuncle, toxic swelling, scrofula, goiter, sore throat；

Rhizoma Chuanxiong, nature and flavor：Pungent, temperature, the effect of with blood-activating and qi-promoting, wind-expelling pain-stopping, for treatment pacify nerve, positive head wind headache, Lump in the abdomen stomachache, chest side of body shouting pain, tumbling and swelling, headache, rheumatic arthralgia；

Herba Hedyotidis Diffusae, nature and flavor：It is bitter sweet, cold, it is nontoxic, the effect of with heat-clearing and toxic substances removing, dampness removing, for treating dyspnea and cough due to lung-heat, pharynx The diseases such as larynx swells and ache, acute appendicitis, furuncle and phyma skin infection, venom, puckery pain of heat gonorrhea, edema, dysentery, enteritis, jaundice due to damp-heat, cancerous protuberance；

The Radix Angelicae Dahuricae, nature and flavor：Warm in nature, acrid in the mouth, gas fragrance, slight bitter, the effect of with wind-damp dispelling, apocenosis of invigorating blood circulation, myogenic pain relieving, for controlling Treat headache, toothache, nasal sinusitis, intestines wind anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus.

Medicine of the present invention is based on the principle of Chinese traditional treatment breast carcinoma, from the pathomechanism according to breast carcinoma and pharmacological action Think：With regard to breast carcinoma, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, there is treatment well to above-mentioned disease Effect.

Specific embodiment

A kind of Chinese medicine formula that the present invention is aiming at the treatment of above-mentioned breast carcinoma and proposes, the medicine prepared using the formula Thing good drug efficacy, instant effect is the Chinese prescription of a treating both the principal and secondary aspects of a disease, is particularly suitable for Clinical practice.With reference to the tool of the present invention Body embodiment is described in further detail：

Embodiment 1：

A kind of Chinese medicine composition for treating breast carcinoma, it is characterised in that each component of the Chinese medicine composition and its matter Amount part is than as follows：

Rhizoma Cyperi 140g, Radix Angelicae Sinensis 140g, Bulbus Fritillariae Thunbergii 95g, Radix Bupleuri 95g, Radix Paeoniae Rubra 95g, Radix Paeoniae Alba 115g, Pericarpium Citri Reticulatae 95g, Semen Vaccariae 95g, It is roasted SQUAMA MANITIS into puffy with sand 95g, Fructus Trichosanthis 120g, Radix Astragali 280g, Rhizoma Polygoni Cuspidati 380g, Flos Lonicerae 280g, Radix Gentianae 50g, Fructus Forsythiae 230g, Rhizoma Chuanxiong 80g, white Serpentis SHECAO 280g, Radix Angelicae Dahuricae 120g.

Embodiment 2：

A kind of Chinese medicine composition for treating breast carcinoma, it is characterised in that each component of the Chinese medicine composition and its matter Amount part is than as follows：

Rhizoma Cyperi 160g, Radix Angelicae Sinensis 160g, Bulbus Fritillariae Thunbergii 105g, Radix Bupleuri 105g, Radix Paeoniae Rubra 105g, Radix Paeoniae Alba 130g, Pericarpium Citri Reticulatae 105g, Semen Vaccariae 105g, roasted SQUAMA MANITIS into puffy with sand 105g, Fructus Trichosanthis 140g, Radix Astragali 310g, Rhizoma Polygoni Cuspidati 420g, Flos Lonicerae 310g, Radix Gentianae 60g, Fructus Forsythiae 260g, Rhizoma Chuanxiong 90g, Herba Hedyotidis Diffusae 310g, Radix Angelicae Dahuricae 140g.

Embodiment 3：

A kind of Chinese medicine composition for treating breast carcinoma, it is characterised in that each component of the Chinese medicine composition and its matter Amount part is than as follows：

Rhizoma Cyperi 180g, Radix Angelicae Sinensis 180g, Bulbus Fritillariae Thunbergii 120g, Radix Bupleuri 120g, Radix Paeoniae Rubra 120g, Radix Paeoniae Alba 150g, Pericarpium Citri Reticulatae 120g, Semen Vaccariae 120g, roasted SQUAMA MANITIS into puffy with sand 120g, Fructus Trichosanthis 160g, Radix Astragali 350g, Rhizoma Polygoni Cuspidati 480g, Flos Lonicerae 350g, Radix Gentianae 70g, Fructus Forsythiae 300g, Rhizoma Chuanxiong 100g, Herba Hedyotidis Diffusae 350g, Radix Angelicae Dahuricae 160g.

Model case

Jing clinical conditions patient with breast cancer totally 470, the age is 300 of more than 35 years old, only 170 be 35 years old with Under.Symptom gradually mitigates or fully recovers in 470 patients 360, effective 110, total effective rate is up to 100%.

Claims (3)

1. a kind of Chinese medicine composition for treating breast carcinoma, it is characterised in that each component of the Chinese medicine composition and its Mass parts are than as follows：

80~180g of Rhizoma Cyperi, 80~180g of Radix Angelicae Sinensis, 30~120g of Bulbus Fritillariae Thunbergii, 30~120g of Radix Bupleuri, 60~120g of Radix Paeoniae Rubra, the Radix Paeoniae Alba 50 ~150g, 30~120g of Pericarpium Citri Reticulatae, 60~120g of Semen Vaccariae, 50~120g of roasted SQUAMA MANITIS into puffy with sand, 90~160g of Fructus Trichosanthis, the Radix Astragali 90~ 350g, 150~480g of Rhizoma Polygoni Cuspidati, 150~350g of Flos Lonicerae, 30~70g of Radix Gentianae, 150~300g of Fructus Forsythiae, 30~100g of Rhizoma Chuanxiong, 150~350g of Herba Hedyotidis Diffusae, 50~160g of the Radix Angelicae Dahuricae.

2. the Chinese medicine composition for treating breast carcinoma according to claim 1, it is characterised in that the Chinese medicine composition Each component and its mass parts than as follows：

90~160g of Rhizoma Cyperi, 90~160g of Radix Angelicae Sinensis, 40~105g of Bulbus Fritillariae Thunbergii, 40~105g of Radix Bupleuri, 70~105g of Radix Paeoniae Rubra, the Radix Paeoniae Alba 60 ~130g, 40~105g of Pericarpium Citri Reticulatae, 70~105g of Semen Vaccariae, 60~105g of roasted SQUAMA MANITIS into puffy with sand, 100~140g of Fructus Trichosanthis, the Radix Astragali 100~ It is 310g, 170~420g of Rhizoma Polygoni Cuspidati, 170~310g of Flos Lonicerae, 40~60g of Radix Gentianae, 170~260g of Fructus Forsythiae, 40~90g of Rhizoma Chuanxiong, white Serpentis 170~310g of SHECAO, 60~140g of the Radix Angelicae Dahuricae.

3. the Chinese medicine composition for treating breast carcinoma according to claim 1 to 2, it is characterised in that the Chinese medicine group Each component of compound and its mass parts are than as follows：

Rhizoma Cyperi 140g, Radix Angelicae Sinensis 140g, Bulbus Fritillariae Thunbergii 95g, Radix Bupleuri 95g, Radix Paeoniae Rubra 95g, Radix Paeoniae Alba 115g, Pericarpium Citri Reticulatae 95g, Semen Vaccariae 95g, It is roasted SQUAMA MANITIS into puffy with sand 95g, Fructus Trichosanthis 120g, Radix Astragali 280g, Rhizoma Polygoni Cuspidati 380g, Flos Lonicerae 280g, Radix Gentianae 50g, Fructus Forsythiae 230g, Rhizoma Chuanxiong 80g, white Serpentis SHECAO 280g, Radix Angelicae Dahuricae 120g.