CN106667950A - Pharmaceutical capsule material - Google Patents
Pharmaceutical capsule material Download PDFInfo
- Publication number
- CN106667950A CN106667950A CN201611072983.5A CN201611072983A CN106667950A CN 106667950 A CN106667950 A CN 106667950A CN 201611072983 A CN201611072983 A CN 201611072983A CN 106667950 A CN106667950 A CN 106667950A
- Authority
- CN
- China
- Prior art keywords
- parts
- capsule
- capsule material
- glycerol
- pharmaceutical capsule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
Abstract
The invention discloses a pharmaceutical capsule material. The pharmaceutical capsule material comprises the following components: gelatin, glycerin triacetate, hydroxypropyl methyl cellulose (HPMC), acetic acid, polyoxyethylene, agar, glycerinum, water and ethylene glycol. The capsule prepared by the pharmaceutical capsule material can be easily absorbed by intestinal tracts, is high in dissolubility, and is capable of effectively reducing injuries to the intestinal tracts of patents.
Description
Technical field
The present invention relates to the technical field of medicinal materials, the more particularly to technical field of capsule for medicine material.
Background technology
Some drugs need to be taken by patient in forms such as powder, molecules, are to solve it to take difficulty, capsule for medicine
Thus produce.In capsule for medicine can be sealed in powder or granular medicament, by patient swallow in the form of entirety, thereafter in intestinal
Digested absorption in road, although this absorpting form avoids the stimulation of drugs on patients's stomach and damages, but while increased
The load of Intestinal Mucosal Injury in Patients Undergoing and the stimulation to Intestinal Mucosal Injury in Patients Undergoing.
The content of the invention
It is an object of the invention to propose a kind of capsule for medicine material that can effectively reduce the stimulation to Intestinal Mucosal Injury in Patients Undergoing.
Technical scheme is as follows：
A kind of capsule for medicine material, including following components：Gelatin, glycerol triacetate, hydroxypropyl methyl cellulose
(HPMC), acetic acid, Polyethylene oxide, agar, glycerol, water, ethylene glycol.
Preferably：In parts by mass, including following components：10~20 parts of gelatin, 0.1~0.5 part of glycerol triacetate,
1~2 part of hydroxypropyl methyl cellulose (HPMC), 0.05~0.1 part of acetic acid, 3~5 parts of Polyethylene oxide, 5~10 parts of agar, glycerol 5
~7 parts, 10~15 parts of water, 5~10 parts of ethylene glycol.
It is also preferred that：The polyoxyethylated molecular weight is 3000~8000.
Obtained capsule of the invention is beneficial to intestinal absorption, and dissolubility is good, can effectively reduce the damage to Intestinal Mucosal Injury in Patients Undergoing.
Specific embodiment
Embodiment 1
A kind of capsule for medicine material, in parts by mass, including following components：10 parts of gelatin, 0.1 part of glycerol triacetate,
1 part of hydroxypropyl methyl cellulose (HPMC), 0.05 part of acetic acid, 3 parts of Polyethylene oxide, 5 parts of agar, 5 parts of glycerol, 10 parts of water, second two
5 parts of alcohol, wherein the polyoxyethylated molecular weight is 3000.
Embodiment 2
A kind of capsule for medicine material, in parts by mass, including following components：20 parts of gelatin, 0.5 part of glycerol triacetate,
2 parts of hydroxypropyl methyl cellulose (HPMC), 0.1 part of acetic acid, 5 parts of Polyethylene oxide, 10 parts of agar, 7 parts of glycerol, 15 parts of water, second two
10 parts of alcohol, wherein the polyoxyethylated molecular weight is 8000.
Claims (3)
1. a kind of capsule for medicine material, it is characterised in that：Including following components：Gelatin, glycerol triacetate, hydroxypropyl methyl is fine
Dimension is plain (HPMC), acetic acid, Polyethylene oxide, agar, glycerol, water, ethylene glycol.
2. capsule for medicine material according to claim 1, it is characterised in that：In parts by mass, including following components：Gelatin
10~20 parts, 0.1~0.5 part of glycerol triacetate, 1~2 part of hydroxypropyl methyl cellulose (HPMC), 0.05~0.1 part of acetic acid,
3~5 parts of Polyethylene oxide, 5~10 parts of agar, 5~7 parts of glycerol, 10~15 parts of water, 5~10 parts of ethylene glycol.
3. capsule for medicine material according to claim 1, it is characterised in that：The polyoxyethylated molecular weight be 3000~
8000。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611072983.5A CN106667950A (en) | 2016-11-29 | 2016-11-29 | Pharmaceutical capsule material |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611072983.5A CN106667950A (en) | 2016-11-29 | 2016-11-29 | Pharmaceutical capsule material |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106667950A true CN106667950A (en) | 2017-05-17 |
Family
ID=58866901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611072983.5A Pending CN106667950A (en) | 2016-11-29 | 2016-11-29 | Pharmaceutical capsule material |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106667950A (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1565411A (en) * | 2003-06-30 | 2005-01-19 | 高俊起 | Medicinal hollow capsule case production method |
| CN102688218A (en) * | 2012-05-24 | 2012-09-26 | 潍坊海之源生物制品有限公司 | Chitosan capsule shell and preparation method thereof |
| CN103260741A (en) * | 2010-10-26 | 2013-08-21 | 比利时胶囊公司 | Bulk enteric capsule shells |
| CN103520727A (en) * | 2012-08-06 | 2014-01-22 | 济南圣泉唐和唐生物科技有限公司 | Capsule shell and preparation method thereof |
| CN104940163A (en) * | 2015-06-24 | 2015-09-30 | 陈威宇 | Capsule shell |
-
2016
- 2016-11-29 CN CN201611072983.5A patent/CN106667950A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1565411A (en) * | 2003-06-30 | 2005-01-19 | 高俊起 | Medicinal hollow capsule case production method |
| CN103260741A (en) * | 2010-10-26 | 2013-08-21 | 比利时胶囊公司 | Bulk enteric capsule shells |
| CN102688218A (en) * | 2012-05-24 | 2012-09-26 | 潍坊海之源生物制品有限公司 | Chitosan capsule shell and preparation method thereof |
| CN103520727A (en) * | 2012-08-06 | 2014-01-22 | 济南圣泉唐和唐生物科技有限公司 | Capsule shell and preparation method thereof |
| CN104940163A (en) * | 2015-06-24 | 2015-09-30 | 陈威宇 | Capsule shell |
Non-Patent Citations (1)
| Title |
|---|
| 王沛主编: "《药物制剂设备》", 31 January 2016, 中国医药科技出版社 * |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170517 |
|
| RJ01 | Rejection of invention patent application after publication |