CN106665561A - Human cell sample storage device for precision medical treatment - Google Patents
Human cell sample storage device for precision medical treatment Download PDFInfo
- Publication number
- CN106665561A CN106665561A CN201710147653.6A CN201710147653A CN106665561A CN 106665561 A CN106665561 A CN 106665561A CN 201710147653 A CN201710147653 A CN 201710147653A CN 106665561 A CN106665561 A CN 106665561A
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- Prior art keywords
- bearing
- positioning table
- cell sample
- plummer
- storage device
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0236—Mechanical aspects
- A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0278—Physical preservation processes
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- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Environmental Sciences (AREA)
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- Mechanical Engineering (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention relates to a human cell sample storage device for precision medical treatment. The human cell sample storage device comprises a bearing base, a protective wall, bearing cavities, circulating pumps, culture medium storage tanks, semiconductor refrigeration devices, electric heating wires, irradiation inactivation devices, a driving power supply and a control system, wherein the bearing base comprises protective side walls, bearing keels, a bearing platform and a positioning table; the bearing cavities are installed in the positioning table by locating holes; each bearing cavity and the corresponding locating hole are distributed in a coaxial way; connecting threads are arranged on the outer side face of the positioning table; the circulating pumps and the culture medium storage tanks are embedded in the bearing keels of the bearing base; the semiconductor refrigeration devices are embedded in the positioning table; the electric heating wires are evenly distributed on the walls of the locating holes and the outer surfaces of the culture medium storage tanks; the irradiation inactivation devices are respectively embedded in the bearing cavities. After the human cell sample storage device is used, a cell storage mode can be flexibly selected; the human cell sample storage device is good in universality and high in use safety, can avoid the pollution, caused by leakage and the like, to the surrounding environment, and can meet the demands of inactivated cell storage and cell activity preservation at the same time.
Description
Technical field
The present invention relates to a kind of medical auxiliary equipment, is exactly a kind of human body cell sample storage for accurate medical treatment
Cryopreservation device.
Background technology
At present during stem cell extraction, cancer sample analyses etc. are carried out, the cell to collecting is generally required
Sample is reliably preserved, and during preservation, in addition it is also necessary to according to the needs for using, the activity guarantor that lives is carried out to cell
Hold and cultivate operation and just two kinds completely different preserving types of inactivation treatment are carried out to cell, in order to meet this needs, when
It is front carry out biological cell preserve when, first as needed respectively using activity keep class container to need keep biological activity
Cell preserved, it is another by inactivating to the container that biological cell inactivation is preserved after preservation, although can meet makes
Needs, but result in current cell, to preserve operation complex, and the rate of comprehensive utilization of equipment is relatively low, and currently
When keeping to biological cytoactive, often mainly biological cell activity is reduced by modes such as freezings and reach holding biology carefully
The purpose of cytoactive, therefore easily cause biological cell activity and be affected, and effectively biological cell cannot be entered during preserving
Row is cultivated, so as to cause more harmful effect to follow-up operation, therefore for this present situation, in the urgent need to exploitation is a kind of
New biological cell save set, to meet the needs of actual work.
The content of the invention
For a kind of not enough present on prior art, human body cell sample storage for accurate medical treatment of present invention offer
Device, the new composition simple structure, integrated, modularity and operation high degree of automation, can flexibly select the storage of cell
Mode, it is universal good and safe to use, can avoid, because leakage etc. pollutes surrounding enviroment, can simultaneously meeting cell
The needs that preservation and cytoactive are preserved after inactivation, while when cytoactive preservation is carried out, it can be ensured that cell Conservation environment shape
State is stablized, and the nutrient substance for maintaining cell bio-activity is provided for cell, it is to avoid cell loss of activity in storing process,
So as to reach the purpose for improving the motility and reliability of cell storage operation.
To achieve these goals, the present invention is by the following technical solutions realizing：
A kind of human body cell sample storage device for accurate medical treatment, including bearing base, protection walls, bearing cavity, circulating pump,
Culture medium storage tank, semiconductor cooling device, electrical heating wire, irradiation inactivated device, driving power supply and control system, bearing base
Including protection side wall, bearing keel, plummer and positioning table, bearing keel is frame structure, and protection side wall is coated on carrying dragon
Outside bone, and airtight cavity structure is constituted, plummer is arranged on the corresponding protection side wall in bearing keel upper surface by turntable mechanism
Outer surface, and be coaxially distributed with bearing keel, plummer is groove-like structure of the cross section in " Qian " font, and plummer upper surface sets
Positioning table, positioning table is arranged on plummer upper surface and is coaxially distributed with plummer, and at least one location hole is set on positioning table, fixed
Position axially bored line and plummer upper surface vertical distribution, bearing cavity at least one are airtight cavity structure and are installed by location hole
In positioning table, bearing cavity is coaxially distributed with location hole, and depth of positioning hole is 1/2-the 3/4 of bearing cavity effective depth, positioning table
Set connection screw thread for lateral surface, and be connected with protection walls by connection screw thread, protection walls be coated on positioning table outer surface and with it is fixed
Airtight cavity structure is constituted between the platform of position, protection walls lower end offsets with plummer upper surface, and circulating pump and culture medium storage tank are extremely
It is few one, it is embedded in the bearing keel of bearing base, and be slidably connected by slide rail between bearing keel, circulating pump passes through water conservancy diversion
Pipe is interconnected respectively with bearing cavity and culture medium storage tank, and at least one water conservancy diversion is separately passed through between bearing cavity and culture medium storage tank
Pipe is interconnected, semiconductor cooling device at least one, is embedded in positioning table and concordant with location hole hole wall, semiconductor refrigerating dress
Put and be distributed in the shape of a spiral around pilot hole axes, electrical heating wire at least two, and be distributed on respectively on location hole hole wall and cultivate
Base storage tank outer surface, irradiation inactivated device is embedded in carrying intracavity, is between the axis and carrying cavity axis of irradiation inactivated device
0 ° of -60 ° of angle, driving power supply and control system are embedded in bearing base, wherein pass through to slide between driving power supply and bearing keel
Rail is slidably connected, control system be arranged on protection side wall inner surfaces, and respectively with circulating pump, semiconductor cooling device, electrical heating
Silk, the electrical connection of irradiation inactivated device, driving power supply, separately set on the protection side wall corresponding to culture medium storage tank and driving power supply
Access hole.
Further, seal groove is set on described plummer, and is connected with the lower surface of protection walls by seal groove, it is described
Seal groove in set elastic sealing ring.
Further, described irradiation inactivated device is ultraviolet inactivation device, electrostatic inactivating device and microwave inactivation dress
Any one in putting.
Further, by any one the structure connection in screw thread, locating button between described positioning table and plummer.
Further, described protection walls inner surface separately sets elastic heat preserving layer.
Further, described bearing cavity side surface top sets transhipment handle, and transports handle at least two, and around holding
Carry cavity axis and be distributed on bearing cavity side surface uniformly, described transhipment handle is hinged with bearing cavity side surface.
This new composition simple structure, integrated, modularity and operation high degree of automation, can flexibly select depositing for cell
Storage mode, it is universal good and safe to use, can avoid, because leakage etc. pollutes surrounding enviroment, can simultaneously meeting thin
The needs that preservation and cytoactive are preserved after born of the same parents' inactivation, while when cytoactive preservation is carried out, it can be ensured that cell Conservation environment
State is stablized, and the nutrient substance for maintaining cell bio-activity is provided for cell, it is to avoid cell loses work in storing process
Property, so as to reach the purpose for improving the motility and reliability of cell storage operation.
Description of the drawings
With reference to the accompanying drawings and detailed description describing the present invention in detail；
Fig. 1 is this new structure schematic diagram.
Specific embodiment
Technological means, creation characteristic, reached purpose and effect to make present invention realization is easy to understand, with reference to concrete
Embodiment, is expanded on further the present invention.
A kind of human body cell sample storage device for accurate medical treatment as described in Figure 1, including bearing base 1, protection
Wall 2, bearing cavity 3, circulating pump 4, culture medium storage tank 5, semiconductor cooling device 6, electrical heating wire 7, irradiation inactivated device 8, drive
Galvanic electricity source 9 and control system 10, bearing base 1 includes protection side wall 101, bearing keel 102, plummer 103 and positioning table
104, bearing keel 102 is frame structure, and protection side wall 101 is coated on outside bearing keel 102, and constitutes airtight cavity structure,
Plummer 103 by turntable mechanism 105 be arranged on the corresponding outer surface of protection side wall 101 in the upper surface of bearing keel 102, and with hold
Carry Os Draconis 102 to be coaxially distributed, plummer 103 is groove-like structure of the cross section in " Qian " font, the upper surface of plummer 103 setting position
Platform 104, positioning table 104 be arranged on the upper surface of plummer 104 and with the coaxial distribution of plummer 103, at least one is set on positioning table 104
Individual location hole 106, the axis of location hole 106 and the upper surface vertical distribution of plummer 103, bearing cavity 3 at least one is airtight cavity
Structure is simultaneously arranged in positioning table 104 by location hole 106, bearing cavity 3 and the coaxial distribution of location hole 106, the depth of location hole 106
For 1/2-the 3/4 of the effective depth of bearing cavity 3, positioning table 104 sets connection screw thread for lateral surface, and by connection screw thread 104 with it is anti-
Retaining wall 2 connects, and protection walls 2 are coated on the outer surface of positioning table 104 and airtight cavity structure, protection walls 2 are constituted between positioning table 104
Lower end offsets with the upper surface of plummer 103, circulating pump 4 and culture medium storage tank 5 equal at least one, is embedded in holding for bearing base 1
Carry in Os Draconis 102, and be slidably connected by slide rail 11 between bearing keel 102, circulating pump 4 pass through mozzle 12 respectively with carrying
Chamber 3 and culture medium storage tank 5 are interconnected, separately mutual by least one mozzle 12 between bearing cavity 3 and culture medium storage tank 5
Connection, semiconductor cooling device 6 at least one is embedded in positioning table 104 and, semiconductor refrigerating concordant with the hole wall of location hole 106
Device 6 is distributed in the shape of a spiral around the axis of location hole 106, electrical heating wire 7 at least two, and is distributed on the hole of location hole 106 respectively
On wall and the outer surface of culture medium storage tank 5, irradiation inactivated device 8 is embedded in bearing cavity 3, the axis of irradiation inactivated device 8 with hold
It is in 0 ° of -60 ° of angle to carry between the axis of chamber 3, and driving power supply 9 and control system 10 are embedded in bearing base 1, wherein driving power supply 9
Be slidably connected by slide rail 11 between bearing keel 102, control system 10 be arranged on protection the inner surface of side wall 101, and respectively with
Circulating pump 4, semiconductor cooling device 6, electrical heating wire 7, irradiation inactivated device 8, driving power supply 9 are electrically connected, culture medium storage
Access hole is separately set on protection side wall 101 corresponding to tank 5 and driving power supply 9.
In the present embodiment, seal groove 13 is set on described plummer 103, and by seal groove 13 and the lower end of protection walls 2
Face connects, and in described seal groove 13 elastic sealing ring 16 is set.
In the present embodiment, described irradiation inactivated device 8 is ultraviolet inactivation device, electrostatic inactivating device and microwave inactivation
Any one in device.
In the present embodiment, by any one knot in screw thread, locating button between described positioning table 104 and plummer 103
Structure connects.
In the present embodiment, the described inner surface of protection walls 2 separately sets elastic heat preserving layer 14.
In the present embodiment, the described side surface of bearing cavity 3 top sets transhipment handle 15, and transports handle 15 at least two,
And the side surface of bearing cavity 3 is distributed on around the axis of bearing cavity 3, described transhipment handle 15 is hinged with the side surface of bearing cavity 3.
Originally it is new first cell sample to be stored in into carrying intracavity in the specific implementation, culture medium is stored in into culture medium
In storage tank, then will be attached by mozzle and circulating pump between bearing cavity and culture medium storage tank, then by protection walls
Install and close, by control system to circulating pump, culture medium storage tank, semiconductor cooling device, electrical heating wire, spoke after closing
Manipulated respectively according to inactivating device, when needing to preserve cell inactivation, then driven irradiation inactivated device and semiconductor refrigerating
Device, carries out inactivating and chilling treatment to cell, and when needing to keep biological activity, then driving cycle pump is by culture medium storage tank
Interior culture medium is transported to carrying intracavity, to maintain cell bio-activity, while driving semiconductor cooling device, electrical heating wire
Guarantee the stability for maintaining cytoactive ambient temperature.
This new composition simple structure, integrated, modularity and operation high degree of automation, can flexibly select depositing for cell
Storage mode, it is universal good and safe to use, can avoid, because leakage etc. pollutes surrounding enviroment, can simultaneously meeting thin
The needs that preservation and cytoactive are preserved after born of the same parents' inactivation, while when cytoactive preservation is carried out, it can be ensured that cell Conservation environment
State is stablized, and the nutrient substance for maintaining cell bio-activity is provided for cell, it is to avoid cell loses work in storing process
Property, so as to reach the purpose for improving the motility and reliability of cell storage operation.
The ultimate principle and principal character and advantages of the present invention of the present invention has been shown and described above.The technology of the industry
Personnel it should be appreciated that the present invention is not restricted to the described embodiments, the simply explanation described in above-described embodiment and description this
The principle of invention, without departing from the spirit and scope of the present invention, the present invention also has various changes and modifications, these changes
Change and improvement is both fallen within scope of the claimed invention.The claimed scope of the invention by appending claims and its
Equivalent thereof.
Claims (6)
1. a kind of for accurate medical human body cell sample storage device, it is characterised in that：The people for accurate medical treatment
Somatic cell sample storage device includes bearing base, protection walls, bearing cavity, circulating pump, culture medium storage tank, semiconductor refrigerating dress
Put, electrical heating wire, irradiation inactivated device, driving power supply and control system, described bearing base includes protection side wall, carries dragon
Bone, plummer and positioning table, described bearing keel is frame structure, and described protection side wall is coated on outside bearing keel, and
Airtight cavity structure is constituted, described plummer is arranged on outside the corresponding protection side wall in bearing keel upper surface by turntable mechanism
Surface, and be coaxially distributed with bearing keel, described plummer is groove-like structure of the cross section in " Qian " font, described carrying
Platform upper surface sets positioning table, and described positioning table is arranged on plummer upper surface and is coaxially distributed with plummer, described positioning
Set at least one location hole on platform, described pilot hole axes and plummer upper surface vertical distribution, the bearing cavity at least
It is individual, be airtight cavity structure and by location hole be arranged on positioning table in, described bearing cavity is coaxially distributed with location hole, described
Depth of positioning hole for bearing cavity effective depth 1/2-3/4, described positioning table sets connection screw thread for lateral surface, and passes through
Connection screw thread is connected with protection walls, and described protection walls are coated on positioning table outer surface and airtight cavity knot is constituted between positioning table
Structure, described protection walls lower end offsets with plummer upper surface, described circulating pump and culture medium storage tank equal at least one, embedding
In the bearing keel of bearing base, and it is slidably connected by slide rail between bearing keel, described circulating pump passes through mozzle
It is interconnected with bearing cavity and culture medium storage tank respectively, it is another between described bearing cavity and culture medium storage tank to pass through at least one
Mozzle is interconnected, described semiconductor cooling device at least one, is embedded in positioning table and, institute concordant with location hole hole wall
The semiconductor cooling device stated is distributed in the shape of a spiral around pilot hole axes, described electrical heating wire at least two, and equal respectively
On location hole hole wall and culture medium storage tank outer surface, described irradiation inactivated device is embedded in carrying intracavity, irradiation inactivated to cloth
It is in 0 ° of -60 ° of angle between the axis and carrying cavity axis of device, described driving power supply and control system is embedded in bearing base
Interior, wherein being slidably connected by slide rail between described driving power supply and bearing keel, described control system is arranged on protection side
Wall inner surface, and electrically connect with circulating pump, semiconductor cooling device, electrical heating wire, irradiation inactivated device, driving power supply respectively
Connect, on the protection side wall corresponding to described culture medium storage tank and driving power supply access hole is separately set.
2. it is according to claim 1 a kind of for accurate medical human body cell sample storage device, it is characterised in that institute
Seal groove is set on the plummer stated, and is connected with the lower surface of protection walls by seal groove, elasticity is set in described seal groove close
Seal ring.
3. it is according to claim 1 a kind of for accurate medical human body cell sample storage device, it is characterised in that institute
The irradiation inactivated device stated is any one in ultraviolet inactivation device, electrostatic inactivating device and microwave inactivation device.
4. it is according to claim 1 a kind of for accurate medical human body cell sample storage device, it is characterised in that institute
By any one the structure connection in screw thread, locating button between the positioning table stated and plummer.
5. it is according to claim 1 a kind of for accurate medical human body cell sample storage device, it is characterised in that institute
The protection walls inner surface stated separately sets elastic heat preserving layer.
6. it is according to claim 1 a kind of for accurate medical human body cell sample storage device, it is characterised in that institute
The bearing cavity side surface top stated sets transhipment handle, and transports handle at least two, and is distributed on carrying around cavity axis are carried
Chamber side surface is uniform, and described transhipment handle is hinged with bearing cavity side surface.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710147653.6A CN106665561A (en) | 2017-03-13 | 2017-03-13 | Human cell sample storage device for precision medical treatment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710147653.6A CN106665561A (en) | 2017-03-13 | 2017-03-13 | Human cell sample storage device for precision medical treatment |
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| CN106665561A true CN106665561A (en) | 2017-05-17 |
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|---|---|---|---|
| CN201710147653.6A Pending CN106665561A (en) | 2017-03-13 | 2017-03-13 | Human cell sample storage device for precision medical treatment |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109009338A (en) * | 2018-07-24 | 2018-12-18 | 姜贺 | A kind of novel operation water knife |
| TWI678966B (en) * | 2018-07-13 | 2019-12-11 | 薩摩亞商Ｓｃｌ生物科技有限公司 | Cell dispensing and storage device and method |
| CN111532561A (en) * | 2020-06-04 | 2020-08-14 | 华中科技大学同济医学院附属协和医院 | Organ transfer box capable of accurately controlling temperature and using method thereof |
| CN111789110A (en) * | 2020-06-30 | 2020-10-20 | 湖北明德健康科技有限公司 | Stem cell constant temperature equipment |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI678966B (en) * | 2018-07-13 | 2019-12-11 | 薩摩亞商Ｓｃｌ生物科技有限公司 | Cell dispensing and storage device and method |
| CN109009338A (en) * | 2018-07-24 | 2018-12-18 | 姜贺 | A kind of novel operation water knife |
| CN111532561A (en) * | 2020-06-04 | 2020-08-14 | 华中科技大学同济医学院附属协和医院 | Organ transfer box capable of accurately controlling temperature and using method thereof |
| CN111789110A (en) * | 2020-06-30 | 2020-10-20 | 湖北明德健康科技有限公司 | Stem cell constant temperature equipment |
| CN111789110B (en) * | 2020-06-30 | 2021-05-07 | 湖北明德健康科技有限公司 | Stem cell constant temperature equipment |
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