CN106659404A - Continuous blood pressure measurement method, apparatus and device - Google Patents

Abstract

A method, device and equipment for continuous blood pressure measurement, the method comprising: obtaining equipment to acquire electrocardiographic signals and photoplethysmographic pulse signals, determining the measured blood pressure according to the electrocardiographic signals and the photoplethysmographic pulse signals, and determining the predicted blood pressure according to the actual measured blood pressure and the determined predicted blood pressure The estimation equation is used to correct the coefficients of the estimation equation, and calculate the blood pressure value according to the adjusted estimation equation. The continuous blood pressure measurement method, device and equipment can improve the accuracy of continuous blood pressure measurement.

Description

Continuous blood pressure measurement method, device and equipment technical field

Embodiments of the present invention relate to medical equipment technology, in particular to a method, device and equipment for continuous blood pressure measurement.

Background technique

Human blood pressure is a very important reference index for human health, especially cardiovascular and cerebrovascular. It is also an important basis for medical workers to diagnose diseases. important means.

In the prior art, there are many ways to measure blood pressure. Among them, using a sphygmomanometer based on pulse wave transmission velocity to measure blood pressure is a way that has been used more in recent years. The electrocardiographic sensor (Electro Cardio Graphy; ECG for short) and the photoelectric sensor (Photo Plethysmor Graphy; PPG for short) at other peripheral tissue locations collect ECG signals and photoplethysmographic pulse signals, and according to the relationship between arterial blood pressure and pulse wave transmission velocity, When the blood pressure rises, the blood vessels dilate and the pulse wave transmission speed increases, otherwise, the pulse wave transmission speed slows down.

However, when the blood pressure is measured based on the pulse wave transmission velocity, the ECG sensor and the photoelectric sensor need to be used for measurement at the same time, which is not suitable for continuous blood pressure detection. The technology of using PPG alone for blood pressure estimation has also been studied, but due to noise such as body motion noise, external interference light or sweat, it will interfere with the photoelectric detection of PPG, resulting in measurement errors, and if continuous blood pressure measurement is performed, then Errors will continue to accumulate, resulting in low accuracy of continuous blood pressure measurement.

Contents of the invention

Embodiments of the present invention provide a method, device and equipment for continuous blood pressure measurement, so as to improve the accuracy of continuous blood pressure measurement.

An embodiment of the present invention provides a continuous blood pressure measurement method, including:

The acquiring device acquires ECG signals and photoplethysmographic pulse signals;

The acquisition device determines the actual Blood pressure;

The acquisition device determines an estimation equation for predicting blood pressure according to the measured blood pressure, corrects coefficients of the estimation equation, and calculates a blood pressure value according to the corrected estimation equation.

With reference to the first aspect, in a first possible implementation manner of the first aspect, the acquisition device acquires the ECG signal, including:

The acquisition device collects electrocardiograms through an electrocardiogram sensor;

The acquisition device performs fast Fourier transform (FFT) processing on the electrocardiogram to obtain a processed signal;

The obtaining device performs noise removal processing on the processed signal to obtain the electrocardiographic signal.

With reference to the first aspect or the first possible implementation manner of the first aspect, in a second possible implementation manner of the first aspect, the acquisition device acquires a photoplethysmography pulse signal, including:

The acquisition device acquires pulse waves through a pulse sensor;

The acquisition device performs fast Fourier transform (FFT) processing on the pulse wave to obtain a processed signal;

The acquisition device performs noise removal processing on the processed signal to obtain the photoplethysmography pulse signal.

With reference to the first aspect, any of the first possible implementation manner of the first aspect to the second possible implementation manner of the first aspect, in a third possible implementation manner of the first aspect, the acquisition device according to the heart The electrical signal and the photoplethysmographic pulse signal determine the measured blood pressure value, comprising:

The obtaining device synchronizes the electrocardiographic signal and the photoplethysmographic pulse signal to obtain a synchronization signal;

The acquisition device calculates the pulse transit time PTT according to the synchronization signal;

The acquisition device determines the measured blood pressure from the PTT.

With reference to the first aspect, the first aspect of the first aspect to any of the third possible implementation manners of the first aspect, in a fourth possible implementation manner of the first aspect, the acquisition device according to the measured Blood pressure and determining an estimation equation for predicting blood pressure, and correcting the coefficients of the estimation equation, including:

The acquisition device performs a second differential on the photoplethysmography pulse signal to obtain a characteristic quantity;

The obtaining device obtains predicted blood pressure according to the characteristic quantity and a preset estimation equation;

The acquisition device corrects the coefficients of the preset estimation equation according to the measured blood pressure and the predicted blood pressure.

In the second aspect, an embodiment of the present invention provides a method for continuous blood pressure measurement, including:

The receiving side device acquires the ECG signal and the photoplethysmography pulse signal;

The receiving-side device determines the measured blood pressure according to the electrocardiographic signal and the photoplethysmographic pulse signal;

The receiving-side device sends the measured blood pressure to the sending-side device, so that the sending-side device can correct the coefficients of the predictive equation according to the measured blood pressure and the predictive equation for determining the predicted blood pressure, and according to the corrected The following predictive equation calculates the blood pressure value.

In a third aspect, an embodiment of the present invention provides a method for continuous blood pressure measurement, including:

The sending-side device acquires the photoplethysmographic pulse signal, and sends the photoplethysmographic pulse signal to the receiving-side device, so that the receiving-side device determines Measured blood pressure;

The sending-side device receives the measured blood pressure sent by the receiving-side device;

The sending-side device corrects the coefficients of the estimated equation according to the measured blood pressure and the estimated equation for determining the predicted blood pressure, and calculates the blood pressure value according to the corrected estimated equation.

In a fourth aspect, an embodiment of the present invention provides a continuous blood pressure measurement device, including:

An acquisition module, configured to acquire electrocardiographic signals and photoplethysmographic pulse signals;

A determining module, configured to determine the measured blood pressure according to the electrocardiographic signal and the photoplethysmographic pulse signal;

The processing module is configured to correct the coefficients of the predictive equation according to the measured blood pressure and the predictive equation for determining the predicted blood pressure, and calculate the blood pressure value according to the corrected predictive equation.

With reference to the fourth aspect, in a first possible implementation manner of the fourth aspect, the acquiring module includes:

The first collection unit is used to collect electrocardiogram through the electrocardiogram sensor;

A first processing unit, configured to perform fast Fourier transform (FFT) processing on the electrocardiogram to obtain a processed signal;

The first processing unit is further configured to perform noise removal processing on the processed signal to obtain the electrocardiographic signal.

In combination with the fourth aspect or the first possible implementation of the fourth aspect, in the second aspect of the fourth aspect In a possible implementation manner, the acquisition module includes:

The second collection unit is used to collect the pulse wave through the pulse sensor;

The second processing unit is configured to perform fast Fourier transform (FFT) processing on the pulse wave to obtain a processed signal;

The second processing unit is configured to perform noise removal processing on the processed signal to obtain the photoplethysmographic pulse signal.

In combination with the fourth aspect and any of the second possible implementation manners from the first aspect to the fourth aspect of the fourth aspect, in the third possible implementation manner of the fourth aspect, the determination module includes:

a synchronization unit, configured to synchronize the electrocardiographic signal and the photoplethysmography pulse signal to obtain a synchronization signal;

a calculation unit, configured to calculate the pulse transit time PTT according to the synchronization signal;

A determining unit, configured to determine the measured blood pressure according to the PTT.

With reference to the fourth aspect and any of the third possible implementation manners from the first aspect to the fourth aspect of the fourth aspect, in the fourth possible implementation manner of the fourth aspect, the processing module includes:

an acquisition unit, configured to perform secondary differentiation on the photoplethysmography pulse signal to obtain a characteristic quantity;

The acquisition unit is configured to obtain predicted blood pressure according to the feature quantity and a preset estimation equation;

A correction unit, configured to correct the coefficients of the preset estimation equation according to the measured blood pressure and the predicted blood pressure.

In the fifth aspect, an embodiment of the present invention provides a device for continuous blood pressure measurement, including:

An acquisition module, configured to acquire electrocardiographic signals and photoplethysmographic pulse signals;

A determining module, configured to determine the measured blood pressure according to the electrocardiographic signal and the photoplethysmographic pulse signal;

A sending module, configured to send the actual measured blood pressure to the sending side device, so that the sending side device can correct the coefficients of the predicted equation according to the actual measured blood pressure and the estimated equation for determining the predicted blood pressure, and according to the corrected The following predictive equation calculates the blood pressure value.

In the sixth aspect, an embodiment of the present invention provides a device for continuous blood pressure measurement, including:

An acquisition module, configured to acquire a photoplethysmography pulse signal;

A sending module, configured to send the photoplethysmographic pulse signal to the receiving side device, to For the receiving side device to determine the measured blood pressure according to the acquired ECG signal and the photoplethysmographic pulse signal;

a receiving module, configured to receive the measured blood pressure sent by the receiving device;

The processing module is configured to correct the coefficients of the predictive equation according to the measured blood pressure and the predictive equation for determining the predicted blood pressure, and calculate the blood pressure value according to the corrected predictive equation.

In a seventh aspect, an embodiment of the present invention provides an acquisition device, including:

The receiver is used to obtain the electrocardiographic signal and the photoplethysmographic pulse signal;

a processor, configured to determine the measured blood pressure according to the electrocardiographic signal and the photoplethysmographic pulse signal;

The processor is further configured to correct the coefficients of the predictive equation according to the measured blood pressure and the predictive equation for determining the predicted blood pressure, and calculate the blood pressure value according to the corrected predictive equation.

With reference to the seventh aspect, in a first possible implementation manner of the seventh aspect, the receiver is further configured to collect electrocardiograms through an electrocardiogram sensor;

The processor is further configured to perform fast Fourier transform (FFT) processing on the electrocardiogram to obtain a processed signal;

The processor is further configured to perform noise removal processing on the processed signal to obtain the electrocardiographic signal.

With reference to the seventh aspect or the first possible implementation manner of the seventh aspect, in a second possible implementation manner of the seventh aspect, the receiver is further configured to collect pulse waves through a pulse sensor;

The processor is further configured to perform fast Fourier transform (FFT) processing on the pulse wave to obtain a processed signal;

The processor is further configured to perform noise removal processing on the processed signal to obtain the photoplethysmographic pulse signal.

With reference to the seventh aspect, the first to the second possible implementation manner of the seventh aspect, in a third possible implementation manner of the seventh aspect, the processor is further configured to use the The electrocardiographic signal is synchronized with the photoplethysmographic pulse signal to obtain a synchronous signal;

The processor is further configured to calculate a pulse transit time PTT according to the synchronization signal;

The processor is further configured to determine the measured blood pressure according to the PTT.

With reference to the seventh aspect and the first to the third possible implementation manner of the seventh aspect, in a fourth possible implementation manner of the seventh aspect, the processor is further configured to: light volume The change tracing pulse signal is subjected to quadratic differentiation to obtain the characteristic quantity;

The processor is further configured to obtain predicted blood pressure according to the feature quantity and a preset estimation equation;

The processor is further configured to correct coefficients of the preset estimation equation according to the measured blood pressure and the predicted blood pressure.

In an eighth aspect, an embodiment of the present invention provides a receiving-side device, including:

The receiver is used to obtain the electrocardiographic signal and the photoplethysmographic pulse signal;

a processor, configured to determine the measured blood pressure according to the electrocardiographic signal and the photoplethysmographic pulse signal;

a transmitter, configured to send the actual measured blood pressure to the sending-side device, so that the sending-side device can correct the coefficients of the estimated equation according to the actual measured blood pressure and the estimated equation for determining the predicted blood pressure, and according to the corrected The following predictive equation calculates the blood pressure value.

In a ninth aspect, an embodiment of the present invention provides a sending-side device, including:

The receiver is used to obtain the photoplethysmography pulse signal;

A transmitter, configured to send the photoplethysmographic pulse signal to a receiving-side device, so that the receiving-side device determines the measured blood pressure according to the electrocardiographic signal and the photoplethysmographic pulse signal;

The receiver is configured to receive the measured blood pressure sent by the receiving device;

The processor is configured to correct the coefficients of the predictive equation according to the measured blood pressure and the predictive equation for determining the predicted blood pressure, and calculate the blood pressure value according to the corrected predictive equation.

In the continuous blood pressure measurement method, device and equipment provided by the embodiments of the present invention, the acquisition device acquires the electrocardiographic signal and the photoplethysmographic pulse signal, determines the measured blood pressure according to the electrocardiographic signal and the photoplethysmographic pulse signal, and determines the predicted blood pressure according to the measured blood pressure and the determined blood pressure The estimated equation is used to perform error correction on the coefficients of the estimated equation, and the blood pressure value is calculated according to the corrected estimated equation. After the measured blood pressure is obtained, the blood pressure is predicted according to the relevant parameters related to the blood pressure and the photoplethysmographic pulse signal, and the coefficients of the prediction equation for determining the predicted blood pressure are corrected by using the measured blood pressure, and according to the corrected prediction equation Calculate the blood pressure value, thereby improving the accuracy of continuous blood pressure measurement.

Description of drawings

In order to more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the following will briefly introduce the drawings that need to be used in the description of the embodiments or the prior art. Obviously, the accompanying drawings in the following description are only These are some embodiments of the present invention. Those skilled in the art can also obtain other drawings based on these drawings without creative work.

Fig. 1 is a schematic flow chart of Embodiment 1 of the continuous blood pressure measurement method of the present invention;

Fig. 2 is a schematic flow chart of Embodiment 2 of the continuous blood pressure measurement method of the present invention;

Fig. 3 is a schematic flow chart of Embodiment 3 of the continuous blood pressure measurement method of the present invention;

Fig. 4 is a schematic flow chart of Embodiment 4 of the continuous blood pressure measurement method of the present invention;

Fig. 5 is a schematic flow chart of Embodiment 5 of the continuous blood pressure measurement method of the present invention;

Fig. 6 is a schematic flowchart of Embodiment 6 of the continuous blood pressure measurement method of the present invention;

Fig. 7 is a schematic flow chart of Embodiment 7 of the continuous blood pressure measurement method of the present invention;

Fig. 8 is a structural schematic diagram of Embodiment 1 of the continuous blood pressure measurement device of the present invention;

Fig. 9 is a schematic structural diagram of Embodiment 2 of the continuous blood pressure measurement device of the present invention;

Fig. 10 is a schematic structural view of Embodiment 3 of the continuous blood pressure measurement device of the present invention;

Fig. 11 is a schematic structural view of Embodiment 4 of the continuous blood pressure measurement device of the present invention;

Fig. 12 is a schematic structural view of Embodiment 5 of the continuous blood pressure measurement device of the present invention;

Fig. 13 is a schematic structural view of Embodiment 6 of the continuous blood pressure measurement device of the present invention;

FIG. 14 is a schematic structural diagram of Embodiment 1 of the acquisition device of the present invention;

FIG. 15 is a schematic structural diagram of Embodiment 1 of receiving-side equipment in the present invention;

FIG. 16 is a schematic structural diagram of Embodiment 1 of the device at the sending side according to the present invention.

detailed description

The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

FIG. 1 is a schematic flowchart of Embodiment 1 of the continuous blood pressure measurement method of the present invention. An embodiment of the present invention provides a continuous blood pressure measurement method, which can be executed by any device that implements the continuous blood pressure measurement method, and the device can be implemented by software and/or hardware. In this embodiment, the apparatus may be integrated into an acquisition device, where the acquisition device may be, for example, a mobile terminal or a wearable device. As shown in Figure 1, the method of this embodiment may include:

Step 101, the acquisition device acquires the electrocardiographic signal and the photoplethysmographic pulse signal.

In this embodiment, the acquisition device acquires the ECG signal through the ECG sensor, and acquires the photoplethysmography pulse signal through the pulse sensor, wherein the ECG sensor may be, for example, an ECG electrode. In practical applications, by placing at least two ECG electrodes at different positions of the acquisition device to obtain ECG signals, for example: at least two ECG electrodes can be placed at positions that can be touched by the user's left and right hands respectively, so as to obtain ECG signals through the ECG electrodes. The user's ECG signal. The present invention does not limit the number of ECG electrodes and specific placement positions.

Step 102, the acquisition device determines the measured blood pressure according to the electrocardiographic signal and the photoplethysmographic pulse signal.

In this embodiment, after acquiring the electrocardiographic signal and the photoplethysmographic pulse signal, the acquisition device jointly determines the user's actual blood pressure according to the electrocardiographic signal and the photoplethysmographic pulse signal.

Step 103, the acquisition device corrects the coefficients of the estimated equation according to the measured blood pressure value and the estimated equation determined to predict the blood pressure, and calculates the blood pressure value according to the corrected estimated equation.

In this embodiment, the establishment of the estimation equation needs to be combined with the input data to perform machine learning in advance. Among them, the input data are parameters related to blood pressure, which include at least one of the following: gender, weight, height, daily pulse, living habits, work and rest schedule, electrocardiogram characteristics, medication status, speed pulse of photoplethysmographic pulse signal, acceleration pulse etc. In the specific implementation process, the photoplethysmography pulse signal can be classified according to each parameter, and then multiple regression analysis is performed on the classified photoplethysmography pulse signal to know the relationship between each parameter and blood pressure, so as to determine Find the most suitable estimation equation, for example: when performing machine learning, classify the photoplethysmography pulse signal according to the user's medication status, if the user is not taking medication, continue to classify according to the user's age... Finally, Divide the photoplethysmography pulse signal into N categories. After the classification, perform multiple regression analysis on the photoplethysmography pulse signal according to the classification results, and obtain the relationship between each parameter and blood pressure, so as to obtain the estimation equation, that is, The prediction equation for calculating the predicted blood pressure is: sBPe=f(t, Ci), where sBPe is the predicted blood pressure, t is the feature quantity, and Ci is a random factor, which is used to adjust the regression effect.

Wherein, for the feature quantity, the acquiring device may acquire the photoplethysmographic pulse signal by performing a differential operation on the photoplethysmographic pulse signal after acquiring the feature quantity. In the specific implementation process, the characteristic quantity can be obtained by differentiating the photoplethysmography pulse signal twice, Wherein, the velocity pulse can be obtained after the photoplethysmography pulse signal is differentiated once, and the acceleration pulse can be obtained after the second differentiation, and then the characteristic quantity can be obtained.

In addition, after the acquisition device obtains the feature quantity, the predicted blood pressure can be calculated according to the prediction equation for calculating the predicted blood pressure determined by machine learning in advance.

In the specific implementation process, as mentioned above, the photoplethysmography pulse signal is classified according to the input data, and then after multiple regression analysis is performed on the classified photoplethysmography pulse signal, correspondingly, the obtained estimation equation is also There will be several groups (n), and which group of prediction equations to use to predict the blood pressure is determined based on the actual blood pressure determined by the acquisition device. Specifically, the measured blood pressure can be taken as the average value X, assuming that the calculated predicted blood pressure is Xi, where _i is the number of predicted blood pressures (number of samples), by calculating the measured blood pressure X and the predicted blood pressure Xi ₍ samples) The standard deviation between S _n . Iteratively use all n groups of prediction equations to obtain the standard deviation S _n of the predicted blood pressure samples and X, if the calculated standard deviation S _j corresponding to the jth predicted blood pressure is the minimum value among all n groups S _n , then select this Group predictor equations (with standard deviation _Sj ) are used for measurements where j is less than or equal to i. For multiple regression analysis, other models can also be used, which is not limited in the present invention.

In the continuous blood pressure measurement method provided by the embodiment of the present invention, the acquisition device acquires the electrocardiographic signal and the photoplethysmographic pulse signal, determines the measured blood pressure according to the electrocardiographic signal and the photoplethysmographic pulse signal, and determines the prediction equation for predicting the blood pressure according to the measured blood pressure and the , performing error correction on the coefficients of the estimation equation, and calculating the blood pressure value according to the corrected estimation equation. After the measured blood pressure is obtained, the blood pressure is predicted according to the relevant parameters related to the blood pressure and the photoplethysmographic pulse signal, and the coefficients of the prediction equation for determining the predicted blood pressure are corrected by using the measured blood pressure, and according to the corrected prediction equation Calculates blood pressure values, thereby improving the accuracy of continuous blood pressure measurements.

Fig. 2 is a schematic flow chart of Embodiment 2 of the continuous blood pressure measurement method of the present invention. This embodiment is based on the first embodiment of the continuous blood pressure measurement method, and describes in detail the embodiment of the acquisition device for obtaining ECG signals. As shown in Figure 2, the method of this embodiment may include:

Step 201, the acquisition device collects electrocardiograms through an electrocardiogram sensor.

In this embodiment, the electrocardiogram collected by the acquisition device is an unprocessed and unprocessed time-series signal.

Step 202, the acquisition device performs fast Fourier transform (FFT) processing on the electrocardiogram to obtain processed signals.

In this embodiment, the acquisition device uses a signal processing circuit to perform A/D conversion and fast Fast Fourier Transform (FFT) processing is used to transform time-domain signals into frequency-domain signals to facilitate signal analysis and processing.

Step 203, the acquisition device performs noise removal processing on the processed signal to obtain the electrocardiographic signal.

In this embodiment, after the acquisition device detects the peak waveform of the ECG in the obtained processed signal, it will perform noise removal processing, wherein the noise removal mainly uses methods such as filtering the signal, for example, through the acceleration sensor After detecting the motion pattern, compare the frequency domain signal fluctuation of the ECG sensor to eliminate the noise introduced due to motion and other reasons.

In the continuous blood pressure measurement method provided by the embodiment of the present invention, the acquisition device collects the electrocardiogram through the electrocardiogram sensor, and processes the electrocardiogram to obtain the processed signal, and then performs noise removal processing on the processed signal to obtain the electrocardiogram signal, which improves the Accuracy of ECG signal measurement.

Fig. 3 is a schematic flow chart of Embodiment 3 of the continuous blood pressure measurement method of the present invention. On the basis of the embodiment shown in Fig. 1 or Fig. 2, this embodiment describes in detail the embodiment in which the acquisition device acquires the photoplethysmographic pulse signal . As shown in Figure 3, the method of this embodiment may include:

Step 301, the acquisition device acquires pulse waves through a pulse sensor.

In this embodiment, the pulse wave collected by the acquisition device is an unprocessed and unprocessed time series signal.

In step 302, the acquisition device performs fast Fourier transform (FFT) processing on the pulse wave to obtain a processed signal.

In this embodiment, the acquisition device uses a signal processing circuit to perform A/D conversion on the pulse wave, and performs FFT processing on the converted signal, thereby transforming the time domain signal into a frequency domain signal to facilitate signal analysis and processing.

Step 303, the acquisition device performs noise removal processing on the processed signal to obtain a photoplethysmography pulse signal.

In this embodiment, after the acquisition device detects the peak waveform of the pulse in the obtained processed signal, it will perform noise removal processing, wherein the noise removal mainly uses methods such as filtering the signal, for example, through an acceleration sensor, etc. The motion pattern is detected, and then the frequency domain signal fluctuation of the pulse sensor is compared to eliminate the noise introduced due to motion and other reasons.

In the continuous blood pressure measurement method provided by the embodiment of the present invention, the acquisition device collects the pulse wave through the pulse sensor, and processes the pulse wave to obtain a processed signal, and then performs noise removal processing on the processed signal to obtain a photoplethysmography pulse signal, Improved accuracy of photoplethysmographic pulse signal measurement. In addition, the photoplethysmography pulse signal is measured by the pulse sensor to achieve for the purpose of continuous measurement.

Fig. 4 is a schematic flow chart of Embodiment 4 of the continuous blood pressure measurement method of the present invention. On the basis of the above-mentioned embodiments, this embodiment will describe in detail the embodiment in which the acquisition device determines the measured blood pressure according to the ECG signal and the photoplethysmographic pulse signal. illustrate. As shown in Figure 4, the method of this embodiment may include:

Step 401. The acquisition device synchronizes the electrocardiographic signal and the photoplethysmographic pulse signal to obtain a synchronization signal.

In this embodiment, since the ECG signal is measured by the ECG sensor, and the photoplethysmography pulse signal is measured by the pulse sensor, the two signals need to be synchronized to find the same ECG pulse signal. R wave and rising point of pulse to calculate the time difference between R wave and rising point of pulse. In a specific implementation process, the synchronization of the electrocardiographic signal and the photoplethysmographic pulse signal can be completed by synchronously aligning the collection time of the electrocardiographic sensor and the pulse sensor.

Step 402, the acquisition device calculates the pulse transmission time PTT according to the synchronization signal.

In this embodiment, assuming that the contraction of the heart and the pumping of blood are simultaneous, the pulse transit time (pulse transit time; PTT for short) can be calculated from the time difference between the R wave of the electrocardiogram and the rising point of the pulse, specifically Specifically, assuming that time a represents the position of the R-wave apex on the ECG signal on the time axis, and time b and time c represent the positions of a bottom point and a vertex on the photoplethysmography pulse signal on the time axis, then The PTT can be obtained by calculating the time difference between time a and time b, or the PTT can be obtained by calculating the time difference between time a and time c. The method for calculating the PTT is not limited in this embodiment.

Step 403, the acquisition device determines the measured blood pressure according to the PTT.

In this embodiment, after the acquisition device calculates the PTT, according to the formula Then the measured blood pressure value P _s can be calculated, where b ₁ , b ₂ and b ₃ are coefficients, which are related to blood vessel elasticity and movement, and T _PTT is the pulse propagation velocity.

In the continuous blood pressure measurement method provided by the embodiment of the present invention, the acquisition device obtains the electrocardiographic signal and the photoplethysmographic pulse signal, and determines the actual blood pressure according to the electrocardiographic signal and the photoplethysmographic pulse signal, and determines the prediction of the predicted blood pressure according to the actual measured blood pressure and the An equation is used to perform error correction on the coefficients of the estimation equation, and calculate the blood pressure value according to the corrected estimation equation. Due to obtaining the measured After the blood pressure is obtained, the device predicts the blood pressure according to the relevant parameters related to the blood pressure and the photoplethysmographic pulse signal, and uses the measured blood pressure to correct the coefficients of the prediction equation for calculating the predicted blood pressure, which improves the accuracy of continuous blood pressure measurement. In addition, the acquisition device can combine the measured photoplethysmography pulse signal to determine the actual blood pressure without adding additional hardware, which simplifies the complexity of the blood pressure measurement device, reduces the cost, and ensures the accuracy of continuous blood pressure detection .

Fig. 5 is a schematic flow chart of Embodiment 5 of the continuous blood pressure measurement method of the present invention. On the basis of the above-mentioned embodiments, the acquisition device calculates the coefficients of the prediction equation according to the actual blood pressure and the prediction equation of the predicted blood pressure. The corrected embodiment will be described in detail. As shown in Figure 5, the method of this embodiment may include:

Step 501 , the acquisition device performs secondary differentiation on the photoplethysmography pulse signal to obtain feature quantities.

In this embodiment, after acquiring the photoplethysmographic pulse signal, the acquiring device can acquire the feature quantity by performing a differential operation on the photoplethysmographic pulse signal. In the specific implementation process, it can be obtained by differentiating the photoplethysmography pulse signal twice, wherein, after the first differentiation of the photoplethysmography pulse signal, the speed pulse can be obtained, and then after the second differentiation, the velocity pulse can be obtained The acceleration pulse is obtained, and then the characteristic quantity can be obtained.

Step 502, the obtaining device obtains the predicted blood pressure according to the feature quantity and the preset estimation equation.

In this embodiment, after the acquiring device acquires the feature value, the predicted blood pressure can be calculated according to the predictive equation for calculating the predicted blood pressure determined in advance through machine learning.

Step 503, the acquisition device corrects the coefficients of the preset estimation equation according to the measured blood pressure and the predicted blood pressure.

In this embodiment, after the acquisition device calculates the predicted blood pressure, it can combine the determined actual blood pressure (for example: systolic blood pressure) to perform multiple regression analysis to correct the coefficients of the estimation equation for calculating the predicted blood pressure, wherein, Multiple regression analysis can use a linear regression model, that is, each parameter related to blood pressure is estimated by least squares to determine the coefficients of the prediction equation. In the specific implementation process, the photoplethysmography pulse signal is classified according to the input data, and then after multiple regression analysis is performed on the classified photoplethysmography pulse signal, the obtained estimation equation will have several groups (n), Which set of estimation equations is used to predict the blood pressure this time is determined according to the actual blood pressure sent by the receiving device. Specifically, the measured blood pressure can be taken as the average value X, and the predicted blood pressure calculated by the hypothetical design is Xi, where _i is the number of predicted blood pressures (number of samples), by calculating the measured blood pressure X and the predicted blood pressure Xi ₍ sample) The standard deviation between S _n . Iteratively use all n groups of prediction equations to obtain the standard deviation S _n of the predicted blood pressure samples and X, if the calculated standard deviation S _j corresponding to the jth predicted blood pressure is the minimum value among all n groups S _n , then select this Group predictor equations (with standard deviation _Sj ) are used for measurements where j is less than or equal to i. For multiple regression analysis, other models can also be used, which is not limited in the present invention.

In the continuous blood pressure measurement method provided by the embodiment of the present invention, the acquisition device obtains the electrocardiographic signal and the photoplethysmographic pulse signal, and determines the actual blood pressure according to the electrocardiographic signal and the photoplethysmographic pulse signal, and determines the prediction of the predicted blood pressure according to the actual measured blood pressure and the An equation is used to perform error correction on the coefficients of the estimation equation, and calculate the blood pressure value according to the corrected estimation equation. After obtaining the measured blood pressure, the acquisition device predicts the blood pressure according to the relevant parameters related to the blood pressure and the photoplethysmography pulse signal, and uses the measured blood pressure to correct the coefficients of the estimation equation for predicting the predicted blood pressure, which improves the accuracy of continuous blood pressure measurement Accuracy.

Fig. 6 is a schematic flowchart of Embodiment 6 of the continuous blood pressure measurement method of the present invention. An embodiment of the present invention provides a continuous blood pressure measurement method, which can be executed by any device that implements the continuous blood pressure measurement method, and the device can be implemented by software and/or hardware. In this embodiment, the apparatus may be integrated into the receiving-side device. As shown in Figure 6, the method of this embodiment may include:

Step 601, the receiving-side device acquires ECG signals and photoplethysmographic pulse signals.

In this embodiment, it is also possible to obtain the ECG signal and the photoplethysmography pulse signal through the receiving-side device, wherein the receiving-side device can be various mobile terminals, such as mobile phones, PADs, etc., and the receiving-side device can pass the ECG sensor to obtain the ECG signal, and obtain the photoplethysmography pulse signal through the pulse sensor.

Step 602, the receiving-side device determines the measured blood pressure according to the electrocardiographic signal and the photoplethysmographic pulse signal.

In this embodiment, after the receiving-side device acquires the electrocardiographic signal and the photoplethysmographic pulse signal, it jointly determines the user's actual blood pressure according to the electrocardiographic signal and the photoplethysmographic pulse signal.

Step 603: The receiving-side device sends the measured blood pressure to the sending-side device, so that the sending-side device can correct the coefficients of the predictive equation according to the measured blood pressure and the predictive equation for determining the predicted blood pressure, and calculate the blood pressure according to the corrected predictive equation value.

In this embodiment, the sending-side device may be any device capable of collecting photoplethysmographic pulse signals, such as a smart bracelet, a smart watch, and the like. After the receiving-side device determines the measured blood pressure, it sends the measured blood pressure to the sending-side device through Bluetooth Low Energy (abbreviation: BLE). The coefficient of the estimated equation is corrected, and after the correction is completed, the blood pressure value is calculated according to the corrected estimated equation.

In the continuous blood pressure measurement method provided by the embodiment of the present invention, the receiving side device obtains the electrocardiographic signal and the photoplethysmographic pulse signal, determines the measured blood pressure according to the electrocardiographic signal and the photoplethysmographic pulse signal, and sends the measured blood pressure to the sending side device , so that the sending-side device corrects the coefficients of the estimated equation according to the actual measured blood pressure and the estimated equation for determining the predicted blood pressure, and calculates the blood pressure value according to the corrected estimated equation. After obtaining the measured blood pressure, the sending device predicts the blood pressure according to the relevant parameters related to the blood pressure and the photoplethysmographic pulse signal, and uses the measured blood pressure to correct the coefficients of the prediction equation for determining the predicted blood pressure, and according to the corrected Predictive equations calculate blood pressure values, thereby improving the accuracy of continuous blood pressure measurements.

Fig. 7 is a schematic flowchart of Embodiment 7 of the continuous blood pressure measurement method of the present invention. An embodiment of the present invention provides a continuous blood pressure measurement method, which can be executed by any device that implements the continuous blood pressure measurement method, and the device can be implemented by software and/or hardware. In this embodiment, the apparatus may be integrated into the sending side device. As shown in Figure 7, the method of this embodiment may include:

Step 701. The transmitting device acquires the Pplethysmographic pulse signal, and sends the Pplethysmographic pulse signal to the receiving device, so that the receiving device can determine the measured blood pressure according to the acquired ECG signal and the Pplethysmographic pulse signal.

In this embodiment, the sending-side device may be any device capable of collecting photoplethysmographic pulse signals, such as a smart bracelet, a smart watch, and the like. After the sending device obtains the pulse signal through the pulse sensor, it does not do any processing on the photoplethysmography pulse signal, but directly sends it to the receiving side device through BLE, and the receiving side device records the pulse signal according to the received photoplethysmography and The ECG signal obtained by itself can determine the user's actual blood pressure. Wherein, the receiving-side device may be various mobile terminals, and by placing ECG electrodes at different positions of the receiving-side device, the user's electrocardiogram signal is acquired.

Step 702, the sending-side device receives the measured blood pressure sent by the receiving-side device.

Step 703: The sending device corrects the coefficients of the estimated equation according to the measured blood pressure and the estimated equation determined to predict the predicted blood pressure, and calculates the blood pressure value according to the corrected estimated equation.

In this embodiment, the establishment of the estimation equation of the sending-side device needs to be combined with the input data to perform machine learning in advance. Among them, the input data are parameters related to blood pressure, which include at least one of the following: gender, weight, height, daily pulse, living habits, work and rest schedule, electrocardiogram characteristics, medication status, speed pulse of photoplethysmographic pulse signal, acceleration pulse etc. In the specific implementation process, the photoplethysmography pulse signal can be classified according to each parameter, and then multiple regression analysis is performed on the classified photoplethysmography pulse signal to know the relationship between each parameter and blood pressure, so as to determine Find the most suitable estimation equation, for example: when performing machine learning, classify the photoplethysmography pulse signal according to the user's medication status, if the user is not taking medication, continue to classify according to the user's age... Finally, Divide the photoplethysmography pulse signal into N categories. After the classification, perform multiple regression analysis on the photoplethysmography pulse signal according to the classification results, and obtain the relationship between each parameter and blood pressure, so as to obtain the estimation equation, that is, The prediction equation for calculating the predicted blood pressure: sBPe=f(t, Ci), where sBPe is the predicted blood pressure, t is the feature quantity, Ci is a random factor, and Ci is used to adjust the regression effect.

Wherein, for the feature quantity, velocity pulse and acceleration pulse, the device at the sending side may obtain the photoplethysmographic pulse signal by performing a differential operation on the photoplethysmographic pulse signal after obtaining it. In the specific implementation process, the characteristic quantity can be obtained by differentiating the photoplethysmography pulse signal twice, wherein, after the first differentiation of the photoplethysmography pulse signal, the velocity pulse can be obtained, and then after the second differentiation , you can get the acceleration pulse.

After calculating the predicted blood pressure according to the determined predictive equation, the transmitting device corrects the coefficients of the predictive equation according to the received measured blood pressure and the calculated predicted blood pressure. After the correction is completed, it calculates according to the corrected predictive equation blood pressure value.

In the continuous blood pressure measurement method provided by the embodiment of the present invention, the sending side device obtains the photoplethysmographic pulse signal, and sends the photoplethysmographic pulse signal to the receiving side device, so that the receiving side device can use the obtained electrocardiogram signal and photovolume change Tracing the pulse signal to determine the measured blood pressure, receiving the measured blood pressure sent by the receiving device, and correcting the coefficients of the preset predictive equation according to the measured blood pressure and determining the predictive equation of the predicted blood pressure, and calculating according to the corrected predictive equation blood pressure value. After obtaining the measured blood pressure, the transmitting device performs error correction on the coefficients of the estimation equation according to the measured blood pressure to calculate the blood pressure value, thereby improving the accuracy of continuous blood pressure measurement.

Fig. 8 is a schematic structural diagram of Embodiment 1 of the continuous blood pressure measurement device of the present invention. As shown in Fig. 8, the continuous blood pressure measurement device provided by the embodiment of the present invention includes an acquisition module 11, a determination module 12 and a processing management module 13.

Wherein, the obtaining module 11 is used to obtain the electrocardiographic signal and the photoplethysmographic pulse signal; the determination module 12 is used to determine the measured blood pressure according to the electrocardiographic signal and the photoplethysmographic pulse signal; the processing module 13 is used to determine the measured blood pressure according to the described The actual blood pressure is measured and the predictive equation for predicting the blood pressure is determined, the coefficients of the predictive equation are corrected, and the blood pressure value is calculated according to the corrected predictive equation.

In the continuous blood pressure measurement device provided by the embodiment of the present invention, the acquisition device acquires the electrocardiographic signal and the photoplethysmographic pulse signal, determines the measured blood pressure according to the electrocardiographic signal and the photoplethysmographic pulse signal, and determines the prediction equation for predicting the blood pressure according to the measured blood pressure and the , performing error correction on the coefficients of the estimation equation, and calculating the blood pressure value according to the corrected estimation equation. After the measured blood pressure is obtained, the blood pressure is predicted according to the relevant parameters related to the blood pressure and the photoplethysmographic pulse signal, and the coefficients of the prediction equation for determining the predicted blood pressure are corrected by using the measured blood pressure, and according to the corrected prediction equation Calculate the blood pressure value, thereby improving the accuracy of continuous blood pressure measurement.

Fig. 9 is a schematic structural diagram of Embodiment 2 of the continuous blood pressure measurement device of the present invention. As shown in Fig. 9, this embodiment is based on the embodiment shown in Fig. 8, and the acquisition module 11 includes:

The first collection unit 111 is used for collecting electrocardiogram through the electrocardiogram sensor;

The first processing unit 112 is configured to perform fast Fourier transform (FFT) processing on the electrocardiogram to obtain a processed signal;

The first processing unit 112 is further configured to perform noise removal processing on the processed signal to obtain the ECG signal.

The device for continuous blood pressure measurement of this embodiment can be used to implement the technical solution of the method for continuous blood pressure measurement provided by any embodiment of the present invention, and its implementation principle and technical effect are similar, and will not be repeated here.

Fig. 10 is a schematic structural diagram of the third embodiment of the continuous blood pressure measurement device of the present invention. As shown in Fig. 10, this embodiment is based on the above-mentioned embodiments, and the acquisition module 11 includes:

The second collection unit 113 is used to collect pulse waves through the pulse sensor;

The second processing unit 114 is configured to perform fast Fourier transform (FFT) processing on the pulse wave to obtain a processed signal;

The second processing unit 114 is configured to perform noise removal processing on the processed signal to obtain the photoplethysmographic pulse signal.

The device for continuous blood pressure measurement in this embodiment can be used to implement the The technical solution of the method for continuous blood pressure measurement provided is similar in principle and technical effect, and will not be repeated here.

Fig. 11 is a schematic structural diagram of Embodiment 4 of the continuous blood pressure measurement device of the present invention. As shown in Fig. 11 , this embodiment is based on the above-mentioned embodiments, and the determination module 12 includes:

The synchronization unit 121 is used to synchronize the electrocardiographic signal and the photoplethysmography pulse signal to obtain a synchronization signal;

The calculation unit 122 is used to calculate the pulse transit time PTT according to the synchronization signal;

The determining unit 123 is configured to determine the measured blood pressure according to the PTT.

Optionally, the processing module 13 includes:

The acquiring unit 131 is configured to perform quadratic differentiation on the photoplethysmographic pulse signal to obtain feature quantities;

The acquisition unit 131 is used to obtain predicted blood pressure according to the feature quantity and a preset estimation equation;

The correction unit 132 is configured to correct the coefficients of the preset estimation equation according to the measured blood pressure and the predicted blood pressure.

The device for continuous blood pressure measurement of this embodiment can be used to implement the technical solution of the method for continuous blood pressure measurement provided by any embodiment of the present invention, and its implementation principle and technical effect are similar, and will not be repeated here.

FIG. 12 is a schematic structural diagram of Embodiment 5 of the continuous blood pressure measurement device of the present invention. As shown in FIG.

Wherein, the obtaining module 21 is used for obtaining the electrocardiographic signal and the photoplethysmographic pulse signal; the determination module 22 is used for determining the measured blood pressure according to the electrocardiographic signal and the photoplethysmographic pulse signal; the sending module 23 is used for sending the The device sends the measured blood pressure, so that the sending side device corrects the coefficients of the predicted equation according to the measured blood pressure and the predicted equation for determining the predicted blood pressure, and calculates the blood pressure value according to the corrected predicted equation .

In the continuous blood pressure measurement device provided by the embodiment of the present invention, the receiving side device obtains the electrocardiographic signal and the photoplethysmographic pulse signal, determines the actual blood pressure according to the electrocardiographic signal and the photoplethysmographic pulse signal, and sends the measured blood pressure to the sending side device , so that the sending side device can correct the coefficients of the estimated equation according to the measured blood pressure and the estimated equation determined to predict the predicted blood pressure, and according to the calibration Positive post-estimated equations to calculate blood pressure values. After obtaining the measured blood pressure, the sending device predicts the blood pressure according to the relevant parameters related to the blood pressure and the photoplethysmographic pulse signal, and uses the measured blood pressure to correct the coefficients of the prediction equation for determining the predicted blood pressure, and according to the corrected Predictive equations calculate blood pressure values, thereby improving the accuracy of continuous blood pressure measurements.

FIG. 13 is a schematic structural diagram of Embodiment 6 of the continuous blood pressure measurement device of the present invention. As shown in FIG.

Wherein, the acquiring module 31 is used to acquire the photoplethysmographic pulse signal; the sending module 32 is used to send the photoplethysmographic pulse signal to the receiving side device, so that the receiving side device can use the acquired electrocardiogram signal and the The photoplethysmographic pulse signal is used to determine the actual measured blood pressure; the receiving module 33 is used to receive the actual measured blood pressure sent by the receiving side device; The coefficient of the estimated equation is corrected, and the blood pressure value is calculated according to the corrected estimated equation.

In the continuous blood pressure measurement device provided by the embodiment of the present invention, the sending side device obtains the photoplethysmographic pulse signal, and sends the photoplethysmographic pulse signal to the receiving side device, so that the receiving side device can use the obtained electrocardiogram signal and photovolume change Tracing the pulse signal to determine the measured blood pressure, receiving the measured blood pressure sent by the receiving device, and correcting the coefficients of the preset predictive equation according to the measured blood pressure and determining the predictive equation of the predicted blood pressure, and calculating according to the corrected predictive equation blood pressure value. After obtaining the measured blood pressure, the transmitting device performs error correction on the coefficients of the estimation equation according to the measured blood pressure to calculate the blood pressure value, thereby improving the accuracy of continuous blood pressure measurement.

FIG. 14 is a schematic structural diagram of Embodiment 1 of the acquisition device of the present invention. As shown in FIG. 14 , the acquisition device provided by the embodiment of the present invention includes a receiver 41 and a processor 42 .

Wherein, the receiver 41 is used to obtain the electrocardiographic signal and the photoplethysmographic pulse signal; the processor 42 is used to determine the measured blood pressure according to the electrocardiographic signal and the photoplethysmographic pulse signal; the processor 42 is also used to According to the measured blood pressure and the estimated equation for determining the predicted blood pressure, the coefficients of the estimated equation are corrected, and the blood pressure value is calculated according to the corrected estimated equation.

The acquisition device provided in this embodiment can be used to implement the technical solution of the method for continuous blood pressure measurement provided in any embodiment of the present invention, and its implementation principle and technical effect are similar, and will not be repeated here.

Optionally, the receiver 41 is also used to collect electrocardiograms through an electrocardiogram sensor;

The processor 42 is also used to perform fast Fourier transform (FFT) processing on the electrocardiogram to obtain have to process the signal;

The processor 42 is also configured to remove noise from the processed signal to obtain the ECG signal.

Optionally, the receiver 41 is also used to collect pulse waves through a pulse sensor;

The processor 42 is also used to perform fast Fourier transform (FFT) processing on the pulse wave to obtain a processed signal;

The processor 42 is further configured to perform noise removal processing on the processed signal to obtain the photoplethysmographic pulse signal.

Optionally, the processor 42 is further configured to synchronize the electrocardiographic signal and the photoplethysmographic pulse signal to obtain a synchronization signal;

The processor 42 is also used to calculate the pulse transit time PTT according to the synchronization signal;

The processor 42 is also used to determine the measured blood pressure according to the PTT.

The processor 42 is also used to perform secondary differentiation on the photoplethysmographic pulse signal to obtain feature quantities;

The processor 42 is further configured to obtain predicted blood pressure according to the feature quantity and a preset estimation equation;

The processor 42 is further configured to correct the coefficients of the preset estimation equation according to the measured blood pressure and the predicted blood pressure.

The acquisition device provided in this embodiment can be used to implement the technical solution of the method for continuous blood pressure measurement provided in any embodiment of the present invention, and its implementation principle and technical effect are similar, and will not be repeated here.

FIG. 15 is a schematic structural diagram of Embodiment 1 of the receiving-side device of the present invention. As shown in FIG. 15 , the sending-side device provided by the embodiment of the present invention includes a receiver 51 , a processor 52 and a transmitter 53 .

The receiver 51 is used to obtain the electrocardiographic signal and the photoplethysmographic pulse signal; the processor 52 is used to determine the measured blood pressure according to the electrocardiographic signal and the photoplethysmographic pulse signal; the transmitter 53 is used to send The actual measured blood pressure is used for the sending side device to correct the coefficients of the estimated equation according to the actual measured blood pressure and the estimated equation for determining the predicted blood pressure, and calculate the blood pressure value according to the corrected estimated equation.

The acquisition device provided in this embodiment can be used to implement the technical solution of the method for continuous blood pressure measurement provided in any embodiment of the present invention, and its implementation principle and technical effect are similar, and will not be repeated here.

Fig. 16 is a schematic structural diagram of Embodiment 1 of the device on the sending side of the present invention. As shown in Fig. 16, the present invention The sending side device provided in this embodiment includes a receiver 61 , a transmitter 62 and a processor 63 .

Wherein, the receiver 61 is used to obtain the photoplethysmographic pulse signal; the transmitter 62 is used to send the photoplethysmographic pulse signal to the receiving side device, so that the receiving side device can obtain the photoplethysmographic pulse signal according to the electrocardiographic signal and the optical pulse signal. The plethysmography pulse signal determines the measured blood pressure; the receiver 61 is used to receive the measured blood pressure sent by the receiving device; the processor 63 is used to determine the estimated blood pressure according to the measured blood pressure and the predictive equation for predicting the blood pressure. The coefficients of the predictive equation are corrected, and the blood pressure value is calculated according to the corrected predictive equation.

The sending-side device provided in this embodiment can be used to implement the technical solution of the method for continuous blood pressure measurement provided in any embodiment of the present invention, and its implementation principle and technical effect are similar, and will not be repeated here.

Those skilled in the art can clearly understand that for the convenience and brevity of description, only the division of the above-mentioned functional modules is used as an example for illustration. In practical applications, the above-mentioned function allocation can be completed by different functional modules according to needs. The internal structure of the device is divided into different functional modules to complete all or part of the functions described above. For the specific working process of the above-described system, device, and unit, reference may be made to the corresponding process in the foregoing method embodiments, and details are not repeated here.

In the several embodiments provided in this application, it should be understood that the disclosed system, device and method can be implemented in other ways. For example, the device embodiments described above are only illustrative. For example, the division of the modules or units is only a logical function division. In actual implementation, there may be other division methods. For example, multiple units or components can be Incorporation may either be integrated into another system, or some features may be omitted, or not implemented. In another point, the mutual coupling or direct coupling or communication connection shown or discussed may be through some interfaces, and the indirect coupling or communication connection of devices or units may be in electrical, mechanical or other forms.

The units described as separate components may or may not be physically separated, and the components shown as units may or may not be physical units, that is, they may be located in one place, or may be distributed to multiple network units. Part or all of the units can be selected according to actual needs to achieve the purpose of the solution of this embodiment.

In addition, each functional unit in each embodiment of the present application may be integrated into one processing unit, each unit may exist separately physically, or two or more units may be integrated into one unit. The above-mentioned integrated units can be implemented in the form of hardware or in the form of software functional units.

If the integrated unit is realized in the form of a software function unit and sold or used as an independent product, it can be stored in a computer-readable storage medium. Based on this understanding, the technical solution of the present application is essentially or part of the contribution to the prior art or all or part of the technical solution can be embodied in the form of a software product, and the computer software product is stored in a storage medium , including several instructions to make a computer device (which may be a personal computer, a server, or a network device, etc.) or a processor (processor) execute all or part of the steps of the methods described in the various embodiments of the present application. The aforementioned storage media include: U disk, mobile hard disk, read-only memory (ROM, Read-Only Memory), random access memory (RAM, Random Access Memory), magnetic disk or optical disc, etc., which can store program codes. .

As mentioned above, the above embodiments are only used to illustrate the technical solutions of the present application, and are not intended to limit them; although the present application has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that: it can still understand the foregoing The technical solutions described in each embodiment are modified, or some of the technical features are equivalently replaced; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the spirit and scope of the technical solutions of the various embodiments of the application.

Claims (21)

1. A kind of continuous BP measurement method, it is characterised in that including：

   Obtain equipment acquisition electrocardiosignal and light Volume Changes trace pulse signal；

   The acquisition equipment traces pulse signal according to the electrocardiosignal and the smooth Volume Changes and determines actual measurement blood pressure；

   The predicting equation formula that equipment is obtained according to the actual measurement blood pressure with determining pre- measuring blood pressure, is corrected, and calculate pressure value according to the predicting equation formula after correction to the coefficient of the predicting equation formula.
2. According to the method described in claim 1, it is characterised in that it is described acquisition equipment obtain electrocardiosignal, including：

   The acquisition equipment gathers electrocardio ripple by EGC sensor；

   The acquisition equipment carries out Fast Fourier Transform (FFT) FFT processing to the electrocardio ripple, obtains process signal；

   The acquisition equipment is removed noise processed to the process signal, obtains the electrocardiosignal.
3. Method according to claim 1 or 2, it is characterised in that the acquisition equipment obtains light Volume Changes and traces pulse signal, including：

   The acquisition equipment gathers pulse wave by pulse transducer；

   The acquisition equipment carries out Fast Fourier Transform (FFT) FFT processing to the pulse wave, obtains process signal；

   The acquisition equipment is removed noise processed to the process signal, obtains the smooth Volume Changes and traces pulse signal.
4. Method according to claim any one of 1-3, it is characterised in that the acquisition equipment traces pulse signal according to the electrocardiosignal and the smooth Volume Changes and determines actual measurement pressure value, including：

   The electrocardiosignal and the smooth Volume Changes are traced pulse signal and synchronized by the acquisition equipment, obtain synchronizing signal；

   The acquisition equipment calculates pulse transit time PTT according to the synchronizing signal；

   The acquisition equipment determines actual measurement blood pressure according to the PTT.
5. Method according to claim any one of 1-4, it is characterised in that predicting equation formula of the acquisition equipment according to the actual measurement blood pressure with determining pre- measuring blood pressure, is corrected to the coefficient of the predicting equation formula, including：

   The acquisition equipment traces pulse signal to the smooth Volume Changes and carries out second differential, obtains feature Amount；

   The acquisition equipment obtains pre- measuring blood pressure according to the characteristic quantity and default predicting equation formula；

   The acquisition equipment is corrected according to the actual measurement blood pressure and the pre- measuring blood pressure to the coefficient of the default predicting equation formula.
6. A kind of continuous BP measurement method, it is characterised in that including：

   Receive side apparatus acquisition electrocardiosignal and light Volume Changes trace pulse signal；

   The reception side apparatus traces pulse signal according to the electrocardiosignal and the smooth Volume Changes and determines actual measurement blood pressure；

   The reception side apparatus sends the actual measurement blood pressure to side apparatus is sent, predicting equation formula for the transmission side apparatus according to the actual measurement blood pressure with determining pre- measuring blood pressure, the coefficient of the predicting equation formula is corrected, and pressure value is calculated according to the predicting equation formula after correction.
7. A kind of method of continuous BP measurement, it is characterised in that including：

   Send side apparatus acquisition light Volume Changes and trace pulse signal, and the smooth Volume Changes are traced into pulse signal be sent to reception side apparatus, tracing pulse signal according to the electrocardiosignal and the smooth Volume Changes of acquisition for the reception side apparatus determines actual measurement blood pressure；

   The side apparatus that sends receives the actual measurement blood pressure for receiving side apparatus transmission；

   The predicting equation formula that side apparatus is sent according to the actual measurement blood pressure with determining pre- measuring blood pressure, is corrected, and calculate pressure value according to the predicting equation formula after correction to the coefficient of the predicting equation formula.
8. A kind of continuous blood pressure measurer, it is characterised in that including：

   Acquisition module, pulse signal is traced for obtaining electrocardiosignal and light Volume Changes；

   Determining module, actual measurement blood pressure is determined for tracing pulse signal according to the electrocardiosignal and the smooth Volume Changes；

   Processing module, for the predicting equation formula according to the actual measurement blood pressure with determining pre- measuring blood pressure, is corrected, and calculate pressure value according to the predicting equation formula after correction to the coefficient of the predicting equation formula.
9. Device according to claim 8, it is characterised in that the acquisition module includes：

   First collecting unit, for gathering electrocardio ripple by EGC sensor；

   First processing units, for carrying out Fast Fourier Transform (FFT) FFT processing to the electrocardio ripple, obtain process signal；

   The first processing units, are additionally operable to be removed the process signal noise processed, obtain the electrocardiosignal.
10. Device according to claim 8 or claim 9, it is characterised in that the acquisition module includes：

    Second collecting unit, for gathering pulse wave by pulse transducer；

    Second processing unit, for carrying out Fast Fourier Transform (FFT) FFT processing to the pulse wave, obtains process signal；

    The second processing unit, for being removed noise processed to the process signal, obtains the smooth Volume Changes and traces pulse signal.
11. Device according to claim any one of 8-10, it is characterised in that the determining module includes：

    Synchronization unit, for tracing pulse signal and synchronizing the electrocardiosignal and the smooth Volume Changes, obtains synchronizing signal；

    Computing unit, for according to the synchronizing signal, calculating pulse transit time PTT；

    Determining unit, for determining actual measurement blood pressure according to the PTT.
12. Device according to claim any one of 8-11, it is characterised in that the processing module includes：

    Acquiring unit, carries out second differential for the smooth Volume Changes to be traced with pulse signal, obtains characteristic quantity；

    The acquiring unit, for according to the characteristic quantity and default predicting equation formula, obtaining pre- measuring blood pressure；

    Unit is corrected, for according to the actual measurement blood pressure and the pre- measuring blood pressure, being corrected to the coefficient of the default predicting equation formula.
13. A kind of device of continuous BP measurement, it is characterised in that including：

    Acquisition module, pulse signal is traced for obtaining electrocardiosignal and light Volume Changes；

    Determining module, actual measurement blood pressure is determined for tracing pulse signal according to the electrocardiosignal and the smooth Volume Changes；

    Sending module, for sending the actual measurement blood pressure to transmission side apparatus, predicting equation formula for the transmission side apparatus according to the actual measurement blood pressure with determining pre- measuring blood pressure, is corrected to the coefficient of the predicting equation formula, and calculates pressure value according to the predicting equation formula after correction.
14. A kind of device of continuous BP measurement, it is characterised in that including：

    Acquisition module, pulse signal is traced for obtaining light Volume Changes；

    Sending module, reception side apparatus is sent to for the smooth Volume Changes to be traced into pulse signal, with Pulse signal is traced according to the electrocardiosignal and the smooth Volume Changes of acquisition for the reception side apparatus and determines actual measurement blood pressure；

    Receiving module, for receiving the actual measurement blood pressure that the reception side apparatus is sent；

    Processing module, for the predicting equation formula according to the actual measurement blood pressure with determining pre- measuring blood pressure, is corrected, and calculate pressure value according to the predicting equation formula after correction to the coefficient of the predicting equation formula.
15. One kind obtains equipment, it is characterised in that including：

    Receiver, pulse signal is traced for obtaining electrocardiosignal and light Volume Changes；

    Processor, actual measurement blood pressure is determined for tracing pulse signal according to the electrocardiosignal and the smooth Volume Changes；

    The processor, is additionally operable to the predicting equation formula with determining pre- measuring blood pressure according to the actual measurement blood pressure, the coefficient of the predicting equation formula is corrected, and calculate pressure value according to the predicting equation formula after correction.
16. Acquisition equipment according to claim 15, it is characterised in that

    The receiver, is additionally operable to gather electrocardio ripple by EGC sensor；

    The processor, is additionally operable to carry out Fast Fourier Transform (FFT) FFT processing to the electrocardio ripple, obtains process signal；

    The processor, is additionally operable to be removed the process signal noise processed, obtains the electrocardiosignal.
17. Acquisition equipment according to claim 15 or 16, it is characterised in that

    The receiver, is additionally operable to gather pulse wave by pulse transducer；

    The processor, is additionally operable to carry out Fast Fourier Transform (FFT) FFT processing to the pulse wave, obtains process signal；

    The processor, is additionally operable to be removed the process signal noise processed, obtains the smooth Volume Changes and traces pulse signal.
18. Acquisition equipment according to claim any one of 15-17, it is characterised in that

    The processor, is additionally operable to that the electrocardiosignal and the smooth Volume Changes are traced pulse signal and synchronized, and obtains synchronizing signal；

    The processor, is additionally operable to, according to the synchronizing signal, calculate pulse transit time PTT；

    The processor, is additionally operable to determine actual measurement blood pressure according to the PTT.
19. Acquisition equipment according to claim any one of 15-18, it is characterised in that

    The processor, is additionally operable to trace the smooth Volume Changes pulse signal progress second differential, obtains Obtain characteristic quantity；

    The processor, is additionally operable to, according to the characteristic quantity and default predicting equation formula, obtain pre- measuring blood pressure；

    The processor, is additionally operable to, according to the actual measurement blood pressure and the pre- measuring blood pressure, be corrected the coefficient of the default predicting equation formula.
20. One kind receives side apparatus, it is characterised in that including：

    Receiver, pulse signal is traced for obtaining electrocardiosignal and light Volume Changes；

    Processor, actual measurement blood pressure is determined for tracing pulse signal according to the electrocardiosignal and the smooth Volume Changes；

    Transmitter, for sending the actual measurement blood pressure to transmission side apparatus, predicting equation formula for the transmission side apparatus according to the actual measurement blood pressure with determining pre- measuring blood pressure, is corrected to the coefficient of the predicting equation formula, and calculates pressure value according to the predicting equation formula after correction.
21. One kind sends side apparatus, it is characterised in that including：

    Receiver, pulse signal is traced for obtaining light Volume Changes；

    Transmitter, reception side apparatus is sent to for the smooth Volume Changes to be traced into pulse signal, and tracing pulse signal according to electrocardiosignal and the smooth Volume Changes for the reception side apparatus determines actual measurement blood pressure；

    The receiver, for receiving the actual measurement blood pressure that the reception side apparatus is sent；

    Processor, for the predicting equation formula according to the actual measurement blood pressure with determining pre- measuring blood pressure, is corrected, and calculate pressure value according to the predicting equation formula after correction to the coefficient of the predicting equation formula.