CN106644635A - Automatic medicine changing device and method for paraffin sections - Google Patents
Automatic medicine changing device and method for paraffin sections Download PDFInfo
- Publication number
- CN106644635A CN106644635A CN201611115408.9A CN201611115408A CN106644635A CN 106644635 A CN106644635 A CN 106644635A CN 201611115408 A CN201611115408 A CN 201611115408A CN 106644635 A CN106644635 A CN 106644635A
- Authority
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- China
- Prior art keywords
- sample bottle
- bottle
- wax
- sliding rail
- drying box
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 239000012188 paraffin wax Substances 0.000 title claims abstract description 31
- 238000000034 method Methods 0.000 title claims abstract description 10
- 239000003814 drug Substances 0.000 title abstract description 9
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 claims abstract description 71
- 239000001993 wax Substances 0.000 claims abstract description 44
- 238000001035 drying Methods 0.000 claims abstract description 41
- 239000007788 liquid Substances 0.000 claims abstract description 41
- 239000002699 waste material Substances 0.000 claims abstract description 18
- 239000008096 xylene Substances 0.000 claims abstract 3
- 235000003140 Panax quinquefolius Nutrition 0.000 claims description 40
- 240000005373 Panax quinquefolius Species 0.000 claims description 40
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 30
- 239000012530 fluid Substances 0.000 claims description 7
- 238000009434 installation Methods 0.000 claims description 6
- 230000001105 regulatory effect Effects 0.000 claims description 6
- 238000007789 sealing Methods 0.000 claims description 4
- 238000009835 boiling Methods 0.000 claims description 3
- 230000002093 peripheral effect Effects 0.000 claims description 3
- 230000000717 retained effect Effects 0.000 claims description 3
- 125000003158 alcohol group Chemical group 0.000 claims description 2
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 claims 6
- 208000005623 Carcinogenesis Diseases 0.000 abstract description 5
- 230000036952 cancer formation Effects 0.000 abstract description 5
- 231100000504 carcinogenesis Toxicity 0.000 abstract description 5
- URLKBWYHVLBVBO-UHFFFAOYSA-N Para-Xylene Chemical group CC1=CC=C(C)C=C1 URLKBWYHVLBVBO-UHFFFAOYSA-N 0.000 description 12
- 239000000463 material Substances 0.000 description 9
- 238000005516 engineering process Methods 0.000 description 4
- 230000001473 noxious effect Effects 0.000 description 4
- 230000018044 dehydration Effects 0.000 description 2
- 238000006297 dehydration reaction Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000003139 buffering effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
Abstract
The invention discloses an automatic medicine changing device and method for paraffin sections. The automatic medicine changing device comprises a box and a drying box, wherein the box is overlapped on the drying box; a sample container, a buffer bottle and a sample containing bottle are mounted in the box, the sample container is connected with the buffer bottle through a connecting pipe, and the sample container is located above the buffer bottle; the buffer bottle is connected with the sample containing bottle through a descending pipe and is located above the sample containing bottle; the sample containing bottle is connected with a waste liquid bottle through a liquid pump; and a wax container, a sample containing bottle and a waste wax bottle are mounted in the drying tank, the wax container is mounted above the sample containing bottle in the drying box, and the sample containing bottle is connected with the waste wax bottle through a pump. According to the automatic medicine changing machine for the paraffin sections, the problems that that a traditional medicine changing is a manual medicine changing manner, the time is wasted, the suck-in of xylene is greatly increased, and xylene belongs to a harmful matter, has strong volatility and a carcinogenesis and severely threatens the personal safety and health are solved.
Description
Technical field
The present invention relates to a kind of automatic dressing changing device and dressing change method, more particularly to a kind of paraffin section automatic dressing changing device
And dressing change method, belong to field of machinery automation.
Background technology
Paraffin section technology is as a basic fundamental in pathology, Developmental Biology, molecular cytology and histology etc.
Extensively apply in field, but paraffin section technology is also the technology of a complexity.Its program is various, and time-consuming longer, dosage is big,
Security is poor.Paraffin section dressing machine exactly compensate for these shortcomings.
Paraffin section early stage is carried out to material, and gradient alcohol dehydration, dimethylbenzene is transparent, and time-consuming for each step, again in time
Dressing, traditional mode of dressing change is artificial dressing, is both lost time, and also considerably increases the suction of paraxylene, dimethylbenzene category
It is serious to threaten personal safety and health with carcinogenesis with strong volatility in noxious material.
The content of the invention
The technical problem to be solved in the present invention is：A kind of paraffin section automatic medicine-change machine is provided, by a kind of paraffin section
Automatic medicine-change machine tradition mode of dressing change is artificial dressing, is both lost time, and also considerably increases the suction of paraxylene, dimethylbenzene
Belong to noxious material, it is serious to threaten personal safety and healthy problem with carcinogenesis with strong volatility.
The technical scheme that the present invention is provided is a kind of paraffin section automatic dressing changing device, including box, drying box are described
The supporting leg of box is placed in drying box top；Shuttle, surge flask are installed in the box body of box and sample bottle cover is contained, it is described
The sample inlet perforate for containing sample bottle cover is fixedly connected by connecting tube with surge flask, and sample export perforate is by connecting tube and gives up
Liquid pump is fixedly connected, and waste drains pump is connected by connecting tube and waste liquid bottle；The upper position of the surge flask that described shuttle is in
Put, surge flask is located at the top position for containing sample bottle cover；Described cartridge bottom has an opening, and aperture position is provided with slip
Track, contains sample bottle and is placed on sliding rail device, contains the upper end open of sample bottle and contains sample bottle cover peripheral dimension and coincide and shape
Into sealing；Sheng wax container is installed in described drying box, sample bottle and slop wax bottle is contained, the Sheng that wax container is arranged in drying box is contained
Sample bottle top position, is contained sample bottle and slop wax bottle and is connected by pump.
Described sliding rail device includes sliding rail bracing frame, sliding rail, sliding rail regulating block, sliding rail
Handle and sliding rail contiguous block.
Described shuttle outlet is provided with quantitative switching.
Described drying box is automatic temperature-controlled drying box, and drying box inner bottom part is provided with the installation that can be adjusted up and down and supports
Frame.
Described sliding rail bracing frame is 4.
Its paraffin section automatic medicine-change method, there is following step：
The first step, by concentration be 50%, 70%, 75%, 80%, 85%, 95%, 100% alcohol respectively according to quantitative switching arrange it is defeated
Send the time to be fed sequentially in surge tank, and be transported in Sheng sample bottle through surge tank, often convey the wine of a variable concentrations
After essence, first pass through drawing liquid pump and take the alcohol that the alcohol for adding each time just adds next concentration away；
Second step, by the dimethylbenzene of 1/2 Sheng sample bottle volume plus 1/2 Sheng sample bottle volume alcohol equivalent mixed liquor according to quantitatively opening
Close the time of delivery for arranging to be delivered in surge tank, and be transported in Sheng sample bottle through surge tank, convey dimethylbenzene and alcohol
Equivalent mixed liquor after, first pass through the equivalent mixed liquor that drawing liquid pump takes alcohol and dimethylbenzene away；
3rd step, by dimethylbenzene according to contain sample bottle cubical content size be repeated twice by quantitative switching arrange time of delivery according to
It is secondary to be delivered in surge tank, after having conveyed dimethylbenzene, first pass through drawing liquid pump take away last addition dimethylbenzene add it is next
The dimethylbenzene of secondary same volume；
4th step, it is to contain the dimethylbenzene of sample bottle 1/2 by volume size, the time of delivery arranged by quantitative switching is delivered to buffering
In tank, and it is transported in Sheng sample bottle through surge tank, and retains the dimethylbenzene of 1/3 Sheng sample bottle volume and is containing in sample bottle, it is unnecessary
Dimethylbenzene is evacuated to waste liquid bottle by drawing liquid pump；
5th step, by step（Four）Remaining dimethylbenzene takes together with sample bottle is contained from Sheng sample bottle attachment rail plane by sample bottle is contained
Go out, and add bottle volume summation 2/3 paraffin consider to be worth doing after be put in drying box, cover Sheng sample bottle cover, by the temperature of drying box
Arrange to 40 DEG C, and constant temperature 14 hours at a temperature of 40 DEG C, then drying box temperature is risen to into 60 DEG C, the lid for containing sample bottle is taken away simultaneously
Stand after 3-4h under 60 DEG C of environment, draw fluid into slop wax bottle with pump immediately；
6th step, continue to add the wax liquor body for boiling, setting to be spaced and be repeated 3 times for 3 ~ 4 hours in wax bottle toward containing, pump is used every time
Draw fluid into slop wax bottle.Until last time conveying liquid wax is retained in Sheng sample bottle, the mistake for entirely changing wax is just completed
Journey.
Described concentration is that 50% alcohol starting alcohol repeats conveying three times, each 30min.
Described concentration be 70% alcohol starting if, in triplicate, each 30min.
A kind of paraffin section automatic medicine-change machine provided by technical scheme, by two cuboid cooperation profiles
Be formed by stacking, put above top it is various needed for change liquid medicine bottle, for the medicine changed needed for holding, above in box by upper
And lower structure, there is individual surge flask the inside, and each medicine is connected by liquid line with surge flask, is had quantitative switching and is loaded work(successively
Can, surge flask is connected with liquid holding bottle by liquid line, is changed liquid and is flowed into Sheng sample bottle by surge flask, contains sample bottle with waste liquid bottle by drawing liquid
Pump is connected, and according to the program setting of time, the liquid contained in sample bottle is extracted out and flowed in waste liquid bottle by certain hour, drawing liquid pump, bottom
Portion's drying box has temperature and time control system, through the dehydration that heats up in paraffin section, after standing is transparent, carries out changing wax, bottom
The wax endured is held in portion's box, wax is pumped in bottle by drawing liquid pump quantitative timing, at the same another drawing liquid pump by its
Slop wax is pumped in wax returnable bottle, it is achieved thereby that automatic medicine-change function.
Described sliding rail device includes sliding rail bracing frame, sliding rail, sliding rail regulating block, sliding rail
Handle and sliding rail contiguous block, by sliding rail, easily can will contain sample bottle and extract out from cartridge bottom, only need to adjust slip
Track upper-lower height, you can realize containing the placement and taking-up of sample bottle.
The shuttle outlet of the present invention is provided with quantitative switching, and the conveying speed of each liquid can be controlled according to quantitative switching
Degree.
The drying box of the present invention is automatic temperature-controlled drying box, and drying box inner bottom part is provided with the installation that can be adjusted up and down and supports
Frame, can easily realize temperature and time control, at the same drying box inner bottom part the installation bracing frame that can be adjusted up and down is installed can
Realize that the locus up and down for containing sample bottle is adjusted with light, can be in position in order to contain sample bottle bottleneck and Sheng sample bottle cover
Sealing.
The sliding rail bracing frame of the present invention is 4, and 4 bracing frames can ensure that stress increases, and increased reliability.
Concentration of the present invention be 50% alcohol need to repeatedly conveying three times, alcohol of the present invention can be from the beginning of 50% concentration, also can be from
70% concentration starts, if if fixer is configured from the beginning of 50%, just repeatedly must convey three times, each 30min.It is dense from 70%
Degree starts, also in triplicate, each 30min.
Compared with prior art, paraffin section dressing machine has saved experimenter's plenty of time, reduces people and chemicals connects
Tactile time and chance, effectively prevent the suction of experimenter's in test paraxylene.
In sum, it is artificial dressing by a kind of paraffin section automatic medicine-change machine tradition mode of dressing change, both lost time,
Also the suction of paraxylene is considerably increased, dimethylbenzene belongs to noxious material, with strong volatility, with carcinogenesis, sternly
The problem of personal safety and health is threatened again.
Description of the drawings
Fig. 1 is the system architecture schematic diagram of the present invention；
Fig. 2 is the sample holder lid top view of the present invention；
Fig. 3 is the box front view of the present invention；
Fig. 4 is the sliding rail structure chart of the present invention；
In figure：1st, shuttle, 2, surge flask, 3, down-comer, 4, contain sample bottle, 5, waste liquid bottle, 6, contain wax container, 7, slop wax bottle,
8th, box, 9, drying box, 10, quantitative switching, 11, drawing liquid pump, 12, pump, 13, sample holder lid, 14, sliding rail, 15, install
Bracing frame, 81, box body, 82, supporting leg, 131, sample inlet perforate, 132, sample export perforate, 141, sliding rail, 142,
Sliding rail bracing frame, 143, sliding rail regulating block, 144, sliding rail handle, 145, sliding rail contiguous block.
Specific embodiment
Below in conjunction with the accompanying drawings and specific embodiment to invention be described further：
As shown in Fig. 1 ~ 4, a kind of paraffin section automatic dressing changing device, including shuttle 1, surge flask 2, down-comer 3, Sheng sample bottle
4th, waste liquid bottle 5, Sheng wax container 6, slop wax bottle 7, box 8, drying box 9, quantitative switching 10, drawing liquid pump 11, pump 12, sample holder lid
13rd, sliding rail 14, box body 81, supporting leg 82, sample inlet perforate 131, sample export perforate 132, sliding rail 141, cunning
Dynamic rail road bracing frame 142, sliding rail regulating block 143, sliding rail handle 144 and sliding rail contiguous block 145；Box 8
Supporting leg 82 is placed in the top of drying box 9；Shuttle 1, surge flask 2 are installed in the box body 81 of box 8 and sample bottle cover 13 is contained,
The described sample inlet perforate 131 for containing sample bottle cover 13 is fixedly connected by connecting tube 3 with surge flask 2, sample export perforate
132 are fixedly connected by connecting tube with waste drains pump 14, and waste drains pump 14 is connected by connecting tube and waste liquid bottle 5；Described sample holds
The top position of the surge flask 2 that device 1 is in, surge flask 2 is located at the top position for containing sample bottle cover 13；The described bottom of box 8
There is an opening, aperture position is provided with sliding rail, contain sample bottle 4 and be placed on sliding rail device 14, contain the upper end of sample bottle 4
Opening and contain the peripheral dimension of sample bottle cover 13 and coincide and form sealing；Sheng wax container 6 is installed in described drying box 9, sample is contained
Bottle 4 and slop wax bottle 7, contain the top position of Sheng sample bottle 4 that wax container 6 is arranged in drying box 9, contain sample bottle 4 and slop wax bottle 7 passes through pump
12 connections.
Further sliding rail device 14 includes that sliding rail bracing frame 142, sliding rail 141, sliding rail are adjusted
Block 143, sliding rail handle 144 and sliding rail contiguous block 145, by sliding rail bracing frame 142 and sliding rail contiguous block
145 are welded, and then sliding rail contiguous block 145 are adopted into bolt or welded and installed in the bottom opening side of box body 81
Position, is then arranged on sliding rail 141 on sliding rail bracing frame 142, is adjusted by sliding rail regulating block 143 and is slided
The high and low position of track 141, to ensure to contain sample bottle 4 and contain sample bottle cover and can seal in position, sliding rail handle
The end face of 144 withdrawal ends that sliding rail 141 is arranged on by screw thread or welding manner, to realize the propulsion and drawing of sliding rail
Go out, the bottom opening size of box body 81 need to meet Sheng sample bottle smoothly can be taken out and be put into from the opening of box body 81.
The further outlet of shuttle 1 is provided with quantitative switching 10, and quantitative switching can ensure that fixer after installing
Transporting velocity, be easy to control to fix fluid dewatering.
Further drying box 9 is automatic temperature-controlled drying box, and drying box inner bottom part is provided with the installation that can be adjusted up and down
Support 15, can easily realize temperature and time control, while drying box inner bottom part is provided with the installation that can be adjusted up and down supporting
Frame can easily realize that the locus up and down for containing sample bottle is adjusted, can be appropriate in order to contain sample bottle bottleneck and Sheng sample bottle cover
Position seals.
Further sliding rail bracing frame 142 is 4, and 4 bracing frames can ensure that stress increases, and increased reliability.
According to above-mentioned technical proposal, after completing the connection of equipment and all parts, you can enter experiment, it is fixed first to set
The time of amount switch 10, then it should be noted that fixer FAA is configured with 50% alcohol, it is dehydrated opening from 50% alcohol
Begin, fixer FAA is configured with 70% alcohol, is dehydrated from the beginning of 70% alcohol.Its 50%FAA is generally used for fixing young tender material
Material or more young tender Pistil And Stamen.70%FAA is generally used for the relatively old material of fixation（Root, stem and leaf）
Test procedure is as follows：
The first step, material take out from fixer FAA, be put into Sheng sample bottle in, by concentration be 50%, 70%, 75%, 80%, 85%,
95%th, the time of delivery that 100% alcohol is arranged respectively according to quantitative switching is fed sequentially in surge tank 2, and through surge tank 2
It is transported in Sheng sample bottle 4, after often having conveyed the alcohol of a variable concentrations, first passes through drawing liquid pump 14 and take the wine for adding each time away
Essence just adds the alcohol of next concentration；
Second step, the dimethylbenzene of the volume of 1/2 Sheng sample bottle 4 arranged plus the alcohol of the volume of 1/2 Sheng sample bottle 4 according to quantitative switching
Time of delivery is delivered in surge tank 2, and is transported in Sheng sample bottle 4 through surge tank 2, has conveyed the equivalent of dimethylbenzene and alcohol
After mixed liquor, first pass through drawing liquid pump 14 and take equivalent mixed liquor away；
3rd step, dimethylbenzene is repeated twice the time of delivery arranged by quantitative switching according to the cubical content size for containing sample bottle 4
It is delivered to successively in surge tank 2, after having conveyed dimethylbenzene, first passes through drawing liquid pump 14 and take the dimethylbenzene of last addition away and add
The dimethylbenzene of same volume next time；
4th step, by the dimethylbenzene that volume size is contain sample bottle 4 1/2, the time of delivery arranged by quantitative switching is delivered to
In surge tank 2, and it is transported in Sheng sample bottle 4 through surge tank 2, and retains the dimethylbenzene of the volume of 1/3 Sheng sample bottle 4 and is containing sample bottle 4
Interior, unnecessary dimethylbenzene is evacuated to waste liquid bottle 5 by drawing liquid pump 14；
5th step, by step（Four）Remaining dimethylbenzene will contain sample bottle together with sample bottle 4 is contained from the attachment rail plane of Sheng sample bottle 4
Take out, and add bottle volume summation 2/3 paraffin consider to be worth doing after be put in drying box, in addition by one be arranged on box body 81 in specification
The same Sheng sample bottle cover is covered on sample bottle is contained, and connects the connecting tube for containing wax container 6 and pump 12, then by the temperature of drying box
Degree is arranged to 40 DEG C, and constant temperature 14 hours at a temperature of 40 DEG C, then drying box temperature is risen to into 60 DEG C, and the lid for containing sample bottle is taken away
（Take off lid）And stand after 3-4h under 60 DEG C of environment, draw fluid into slop wax bottle with pump immediately；
6th step, continue to add the wax liquor body for boiling, setting to be spaced and be repeated 3 times for 3 ~ 4 hours in wax bottle toward containing, pump is used every time
Draw fluid into slop wax bottle.Until last time conveying liquid wax is retained in Sheng sample bottle, the mistake for entirely changing wax is just completed
Journey.
Further concentration is that 50% alcohol need to be conveyed repeatedly three times, and alcohol of the present invention can also may be used from the beginning of 50% concentration
From the beginning of 70% concentration, if if fixer is configured from the beginning of 50%, just repeatedly must convey three times, each 30min.70% is dense
Degree starts, and also repeats three times, each 30min.
Compared with prior art, paraffin section dressing machine has saved experimenter's plenty of time, reduces people and chemicals connects
Tactile time and chance, effectively prevent the suction of experimenter's in test paraxylene.
In sum, it is artificial dressing by a kind of paraffin section automatic medicine-change machine tradition mode of dressing change, both lost time,
Also the suction of paraxylene is considerably increased, dimethylbenzene belongs to noxious material, with strong volatility, with carcinogenesis, sternly
The problem of personal safety and health is threatened again.
Above content is to combine specific preferred embodiment further description made for the present invention, it is impossible to assert
The present invention be embodied as be confined to these explanations.For general technical staff of the technical field of the invention,
On the premise of without departing from present inventive concept, some simple deduction or replace can also be made, should all be considered as belonging to the present invention's
Protection domain.
Claims (9)
1. a kind of paraffin section automatic dressing changing device, including box（8）, drying box（9）, it is characterised in that：Described box（8）
Supporting leg（82）It is placed in drying box（9）Top；Box（8）Box body（81）Shuttle is inside installed（1）, surge flask（2）
With Sheng sample bottle cover（13）, described Sheng sample bottle cover（13）Sample inlet perforate（131）By connecting tube（3）And surge flask
（2）It is fixedly connected, sample export perforate（132）By connecting tube and waste drains pump（14）It is fixedly connected, waste drains pump（14）By even
Adapter and waste liquid bottle（5）Connection；Described shuttle（1）The surge flask being in（2）Top position, surge flask（2）It is located at
Contain sample bottle cover（13）Top position；Described box（8）One opening is arranged at bottom, and aperture position is provided with sliding rail,
Contain sample bottle（4）It is placed on sliding rail device（14）On, contain sample bottle（4）Upper end open and contain sample bottle cover（13）Peripheral dimension
It coincide and is formed sealing；Described drying box（9）Sheng wax container is inside installed（6）, contain sample bottle（4）With slop wax bottle（7）, contain wax and hold
Device（6）Installed in drying box（9）Interior Sheng sample bottle（4）Top position, contains sample bottle（4）With slop wax bottle（7）By pump（12）Connection.
2. a kind of paraffin section automatic dressing changing device according to claim 1, it is characterised in that：Described sliding rail dress
Put（14）Including sliding rail bracing frame（142）, sliding rail（141）, sliding rail regulating block（143）, sliding rail handle
（144）With sliding rail contiguous block（145）.
3. a kind of paraffin section automatic dressing changing device according to claim 1, it is characterised in that：Described shuttle
（1）Outlet is provided with quantitative switching（10）.
4. a kind of paraffin section automatic dressing changing device according to claim 1, it is characterised in that：Described drying box（9）
For automatic temperature-controlled drying box, drying box（9）Inner bottom part is provided with the installation bracing frame that can be adjusted up and down.
5. a kind of paraffin section automatic dressing changing device according to claim 2, it is characterised in that：Sliding rail bracing frame
（142）For 4.
6. a kind of paraffin section automatic medicine-change method, there is following step：
The first step, by concentration be 50%, 70%, 75%, 80%, 85%, 95%, 100% alcohol respectively according to quantitative switching arrange it is defeated
The time is sent to be fed sequentially into surge tank（2）It is interior, and through surge tank（2）It is transported to Sheng sample bottle（4）It is interior, often convey once different
After the alcohol of concentration, drawing liquid pump is first passed through（14）Take the alcohol that the alcohol for adding each time just adds next concentration away；
Second step, by 1/2 contain sample bottle（4）The dimethylbenzene of volume contains sample bottle plus 1/2（4）The equivalent mixed liquor of volume is according to quantitative
The time of delivery that switch is arranged is delivered to surge tank（2）It is interior, and through surge tank（2）It is transported to Sheng sample bottle（4）It is interior, convey two
After the mixed in equal amounts of toluene and alcohol, drawing liquid pump is first passed through（14）Take alcohol, dimethylbenzene equivalent mixed liquor away；
3rd step, by dimethylbenzene according to contain sample bottle（4）Cubical content size be repeated twice by quantitative switching arrange conveying when
Between be delivered to surge tank successively（2）It is interior, after having conveyed xylene solution, first pass through drawing liquid pump（14）Take the two of last addition away
Toluene adds the dimethylbenzene of same volume next time；
4th step, by volume size for contain sample bottle（4）1/2 dimethylbenzene, the time of delivery arranged by quantitative switching is delivered to
Surge tank（2）It is interior, and through surge tank（2）It is transported to Sheng sample bottle（4）It is interior, and retain 1/3 Sheng sample bottle（4）The dimethylbenzene of volume exists
Contain sample bottle（4）Interior, unnecessary dimethylbenzene passes through drawing liquid pump（14）It is evacuated to waste liquid bottle（5）；
5th step, by step（Four）Remaining dimethylbenzene even contains sample bottle（4）Together from Sheng sample bottle（4）Attachment rail plane will be contained
Sample bottle take out, and add bottle volume summation 2/3 paraffin consider to be worth doing after be put in drying box, cover Sheng sample bottle cover, by drying box
Temperature setting to 40 DEG C, and constant temperature 14 hours at a temperature of 40 DEG C, then drying box temperature is risen to into 60 DEG C will contain the lid of sample bottle
Take away（Take off lid）And stand after 3-4h under 60 DEG C of environment, draw fluid into slop wax bottle with pump immediately；
6th step, continue to add the wax liquor body for boiling, setting to be spaced and be repeated 3 times for 3 ~ 4 hours in wax bottle toward containing, pump is used every time
Draw fluid into slop wax bottle.
7., until last time conveying liquid wax is retained in Sheng sample bottle, the process for entirely changing wax is just completed.
8. a kind of paraffin section automatic medicine-change method according to claim 6, it is characterised in that：Described concentration is 50%
Alcohol starting alcohol repeat conveying three times, each 30min.
9. a kind of paraffin section automatic medicine-change method according to claim 6, it is characterised in that：Described concentration is 70%
If alcohol starting, in triplicate, each 30min.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611115408.9A CN106644635A (en) | 2016-12-07 | 2016-12-07 | Automatic medicine changing device and method for paraffin sections |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611115408.9A CN106644635A (en) | 2016-12-07 | 2016-12-07 | Automatic medicine changing device and method for paraffin sections |
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| Publication Number | Publication Date |
|---|---|
| CN106644635A true CN106644635A (en) | 2017-05-10 |
Family
ID=58820112
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611115408.9A Pending CN106644635A (en) | 2016-12-07 | 2016-12-07 | Automatic medicine changing device and method for paraffin sections |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112945657A (en) * | 2021-01-22 | 2021-06-11 | 中国科学院东北地理与农业生态研究所 | Pretreatment device and method for preparing plant material paraffin section |
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| CN203191234U (en) * | 2013-01-16 | 2013-09-11 | 长沙康柏恩医疗科技有限公司 | Fast-slow type double-purpose automatic biological tissue dehydrator of single-specimen processing cylinder |
| CN104048871A (en) * | 2013-03-11 | 2014-09-17 | 李朝林 | Environmental protective automatic continuous paraffin-embedding device |
| CN103969096A (en) * | 2014-04-23 | 2014-08-06 | 杭州电子科技大学 | Automatic cell paraffin block preparation device and method |
| CN104297041A (en) * | 2014-10-24 | 2015-01-21 | 李静 | Multifunctional and full-automatic embedding machine for tissue dehydration, positioning and embedding and using method thereof |
| CN105241700A (en) * | 2015-09-25 | 2016-01-13 | 湖北泰维科技实业有限公司 | Method for preventing full-closed automatic dewatering machine pipeline from clogging, and anti-clogging paraffin heating control system |
| CN105352775A (en) * | 2015-12-11 | 2016-02-24 | 武汉纺织大学 | Full automatic paraffin-embedded tissue section deparaffinating system |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN112945657A (en) * | 2021-01-22 | 2021-06-11 | 中国科学院东北地理与农业生态研究所 | Pretreatment device and method for preparing plant material paraffin section |
| CN112945657B (en) * | 2021-01-22 | 2023-08-25 | 中国科学院东北地理与农业生态研究所 | Pretreatment device and method for preparing plant material paraffin section |
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