CN106621510B - Soft material polymer precision filter for transfusion and manufacturing method thereof - Google Patents
Soft material polymer precision filter for transfusion and manufacturing method thereof Download PDFInfo
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- CN106621510B CN106621510B CN201710039624.8A CN201710039624A CN106621510B CN 106621510 B CN106621510 B CN 106621510B CN 201710039624 A CN201710039624 A CN 201710039624A CN 106621510 B CN106621510 B CN 106621510B
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- 238000004519 manufacturing process Methods 0.000 title claims abstract description 22
- 239000007779 soft material Substances 0.000 title claims abstract description 18
- 229920000642 polymer Polymers 0.000 title claims abstract description 16
- 239000007788 liquid Substances 0.000 claims abstract description 27
- 238000001914 filtration Methods 0.000 claims abstract description 17
- 239000000463 material Substances 0.000 claims abstract description 6
- 239000012528 membrane Substances 0.000 claims description 46
- 238000001802 infusion Methods 0.000 claims description 16
- 238000003466 welding Methods 0.000 claims description 7
- 238000013329 compounding Methods 0.000 claims description 5
- 238000007789 sealing Methods 0.000 claims description 4
- 239000004677 Nylon Substances 0.000 claims description 3
- 239000004695 Polyether sulfone Substances 0.000 claims description 3
- 238000005520 cutting process Methods 0.000 claims description 3
- 239000000835 fiber Substances 0.000 claims description 3
- 229920001778 nylon Polymers 0.000 claims description 3
- 229920006284 nylon film Polymers 0.000 claims description 3
- 229920000728 polyester Polymers 0.000 claims description 3
- 229920006267 polyester film Polymers 0.000 claims description 3
- 229920006393 polyether sulfone Polymers 0.000 claims description 3
- 210000004379 membrane Anatomy 0.000 claims 8
- 210000002469 basement membrane Anatomy 0.000 claims 2
- 230000001815 facial effect Effects 0.000 claims 2
- 239000003814 drug Substances 0.000 abstract description 17
- 239000002245 particle Substances 0.000 description 7
- 238000000034 method Methods 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 230000008569 process Effects 0.000 description 4
- 238000010923 batch production Methods 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 208000010378 Pulmonary Embolism Diseases 0.000 description 1
- 238000001467 acupuncture Methods 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 208000026106 cerebrovascular disease Diseases 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000007905 drug manufacturing Methods 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 210000004761 scalp Anatomy 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 230000001502 supplementing effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D29/00—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor
- B01D29/01—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with flat filtering elements
- B01D29/03—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with flat filtering elements self-supporting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/36—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests with means for eliminating or preventing injection or infusion of air into body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/75—General characteristics of the apparatus with filters
- A61M2205/7536—General characteristics of the apparatus with filters allowing gas passage, but preventing liquid passage, e.g. liquophobic, hydrophobic, water-repellent membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/75—General characteristics of the apparatus with filters
- A61M2205/7545—General characteristics of the apparatus with filters for solid matter, e.g. microaggregates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2207/00—Methods of manufacture, assembly or production
Abstract
The invention provides a soft material high polymer precision filter for transfusion and a manufacturing method thereof, wherein the soft material high polymer precision filter comprises the following steps: the filter bag is made of a light film material, and a filter cavity and a liquid discharge cavity are formed in the filter bag by arranging a precise filter screen; the upper end of the filter bag is provided with an input joint and a dosing joint which are both communicated with the liquid discharge cavity; the lower end of the filter bag is provided with an output joint which is communicated with the liquid discharge cavity, and the filter bag is also provided with an exhaust device. The filter has the advantages of low cost, safe filtration, convenient use and capability of feeding medicine.
Description
[ technical field ] A method for producing a semiconductor device
The invention relates to the technical field of medical instruments, in particular to a soft material high polymer precision filter for infusion.
[ background of the invention ]
At present, infusion therapy is an essential means for clinical treatment and medication as an important means for supplementing body fluid and an effective means for providing various nutrient components in vivo. However, for many years, in clinical treatment, infusion has been exposed to the potential risk of blood contamination and the insoluble particles in the veins are a serious risk to human health.
In the process of infusion by using a common filtering infusion set, insoluble particles in the medicine enter the human body while infusion, when the insoluble particles reach a certain amount, cardiovascular and cerebrovascular diseases and pulmonary artery embolism are easily induced, mild patients can cause blood circulation disorder, severe patients can cause organ necrosis, and serious life crisis. Therefore, the control of insoluble particles has become a subject of general attention in medical care in the world.
In order to solve the above problems, the drug production process should be strictly controlled to regulate the production and quality of infusion sets and injection sets, but the safest, simple and effective method is to use terminal filtration.
At present, infusion sets with terminal filtering functions are widely used clinically in the process of drip infusion for disease treatment. However, the insoluble particles of 15 μm or more can be filtered, and the particles of 15 μm or less cannot be filtered. In recent years, filters capable of filtering insoluble particles of more than 5 microns appear in the market, but because the problem of product structure easily generates gathered bubbles in the using process, although the top of the filter is provided with an exhaust hole, most of the bubbles cannot be removed, and the bubbles have the risk of entering a transfusion pipeline at any time, the risk of air entering blood circulation is greatly improved, and potential safety hazards are caused. Moreover, the material of the existing medical infusion tube filter is a transparent plastic shell, so that the cost is high, the manufacturing process is complex, mass production cannot be realized, manual assembly is realized during assembly, and the production efficiency and the yield are low.
[ summary of the invention ]
In order to avoid the above-mentioned situation, the invention provides a soft material high-molecular precision filter for transfusion and a manufacturing method thereof. The filter is low in cost, safe in filtering and convenient to use, and can be used for adding medicine midway.
In order to achieve the purpose, the invention adopts the following technical means:
a soft material polymer precision filter for transfusion comprises: the filter bag is made of a light film material, and a filter cavity and a liquid discharge cavity are formed in the filter bag by arranging a precise filter screen; the upper end of the filter bag is provided with an input joint and a dosing joint which are both communicated with the liquid discharge cavity; the lower end of the filter bag is provided with an output joint which is communicated with the liquid discharge cavity, and the filter bag is also provided with an exhaust device.
The precise filter screen comprises a silk screen, a filter membrane and a lining membrane, wherein the silk screen is arranged on one side close to the liquid discharge cavity, the filter membrane is arranged on the silk screen, the lining membrane covers the filter membrane, and the lining membrane is arranged on one side close to the filter cavity.
The filter membrane is a nuclear microporous filter membrane, a polyether sulfone membrane, a polyester membrane or a nylon membrane; the lining film is a fiber film, a nylon film or a polyester film.
The filtering aperture of the filter membrane is 1.2-15 microns.
The exhaust device is an exhaust pipe, the exhaust pipe is arranged at the top of the filter bag, and the exhaust pipe is communicated with the filter cavity or the liquid discharge cavity.
The exhaust device is an exhaust hole, one side surface of the filter bag is provided with an exhaust hole or both side surfaces of the filter bag are provided with exhaust holes, and one or more exhaust holes are arranged on the side surface of the filter bag; and a water-blocking film is arranged on the inner wall of the filter bag provided with the exhaust holes.
Before the air vent is not used, an air film for sealing the air vent is arranged on the air vent.
The precise filter screen is arranged between two side walls of the filter bag and is integrally welded by ultrasonic waves or formed by high-frequency heat welding.
The input joint and the output joint are both luer joints or quick-plug joints.
The filter bag is made of a medical transparent soft material.
Compared with the prior art, the invention has the following advantages:
the invention realizes the impurity filtration of the liquid medicine before being injected into the body of a patient by arranging the precise filter screen in the filter bag, and simultaneously discharges bubbles through the exhaust pipe, thereby ensuring that no bubbles exist in the liquid medicine. The whole production process is realized by mechanical automation, batch production can be realized, manual assembly is not needed in the production process, the production efficiency is improved, and the product percent of pass is improved.
Furthermore, the precise filter screen is formed by compounding or welding the filter membrane and the lining membrane on a silk screen, so that the filter bag is ensured to have certain support. The coarse filtration of the lining membrane and the further fine filtration of the filter membrane form a three-layer filtration structure, so that the filtration efficiency and the effect are both greatly improved.
[ description of the drawings ]
FIG. 1 is a schematic view of a soft polymer precision filter for infusion;
FIG. 2 is a sectional view of a soft polymer precision filter for transfusion;
FIG. 3 is a schematic view of a filter mesh;
FIG. 4 is a diagram of an embodiment of a soft polymer precision filter for infusion;
FIG. 5 is a view showing another embodiment of a soft polymer precision filter for transfusion;
wherein, 1 is an input joint; 2 is an exhaust pipe; 3 is a dosing joint; 4 is a filter bag; 5 is a breather hole; 6 is an output joint; 7 is a precision filter screen; 8 is a water-resistant film; 9 is a silk screen; 10 is a filter membrane; and 11 is a lining film.
[ detailed description ] A
The invention will be further described with reference to the accompanying drawings and specific examples, which are not intended to limit the invention to the following examples.
As shown in fig. 1, a soft polymer precision filter for infusion, comprising: the filter bag 4 is made of light film material, and a filter cavity and a liquid discharge cavity are formed in the filter bag 4 by arranging a precise filter screen 7; the upper end of the filter bag 4 is provided with an input joint 1 and a dosing joint 3, and the input joint 1 and the dosing joint 3 are both communicated with the liquid discharge cavity; the lower end of the filter bag 4 is provided with an output joint 6, the output joint 6 is communicated with the liquid discharge cavity, and the filter bag 4 is also provided with an exhaust device. Before the air vent 5 is not used, an air film for sealing the air vent is arranged on the air permeable shell 9. The precise filter screen 7 is arranged between two side walls of the filter bag 4 and is integrally welded by ultrasonic waves or formed by high-frequency heat welding. The input connector 1 and the output connector 6 are both luer connectors or quick connectors. The material of the filter bag 4 is medical transparent soft material, such as PVC.
As shown in fig. 1, the exhaust device is an exhaust pipe 2, the exhaust pipe 2 is arranged on the top of the filter bag 4, and the exhaust pipe 2 is communicated with the filter chamber or the liquid discharge chamber.
As shown in fig. 3, the fine filter screen 7 includes a screen 9, a filter membrane 10 and a lining membrane 11, the screen 9 is disposed near one side of the liquid discharge chamber, the filter membrane 10 is disposed on the screen 9, the lining membrane 11 covers the filter membrane 10, and the lining membrane 11 is disposed near one side of the filter chamber. The filter membrane 10 is a nuclear microporous filter membrane (heavy ion membrane), a polyether sulfone membrane, a polyester membrane or a nylon membrane; the lining film 11 is a fiber film, a nylon film or a polyester film. The filtration pore diameter of the filter membrane 10 is 1.2-15 microns.
As shown in fig. 2, 4 and 5, a vent 5 is provided on one side wall of the filter bag 4, and the vent 5 prevents the liquid medicine from flowing out through a water-blocking film 8 provided on the inner wall of the filter bag 4. The exhaust device is an exhaust hole 5, one side surface of the filter bag 4 is provided with the exhaust hole 5 or both side surfaces are provided with the exhaust holes 5, and one or more exhaust holes 5 are arranged on the side surface of the filter bag 4; the inner wall of the filter bag 4 provided with the exhaust holes 5 is provided with a water-resisting film 8.
The filter bags 4 are, in practice, about 7.5 x 5cm in size. The precise filter screen 7 is arranged between two side walls of the filter bag 4 and is integrally welded and formed by ultrasonic waves.
The working principle of the invention is as follows:
when the filter is used, the input connector 1 of the filter is connected with an infusion tube, liquid medicine enters the filter cavity from the input connector 1, bubbles carried by the liquid medicine enter the cavity and are discharged from the exhaust tube 2, the liquid medicine in the filter cavity sequentially enters the liquid discharge cavity from the lining film 11, the filter film 10 and the silk screen 9 of the precise filter screen 7 to carry out a filtering process, and the filtered liquid medicine enters a scalp acupuncture from the output connector 6 to carry out normal infusion. When the medicine needs to be added, the medicine adding connector 3 can be connected for adding medicine. The connector all uses luer to connect, and convenient and the joint of transfer line realize quick installation, realize the standardization that the medicine field connects, avoid unmatched situation. All the liquid medicine entering the human body is filtered, so that the safety of the patient is ensured.
In the production process, holes (exhaust holes 5) are uniformly distributed on a rectangular transparent soft material, then a water blocking film 8 is welded (or compounded) on the side wall of the corresponding exhaust hole 5, then a precise filter screen 7 is stacked on the transparent soft material with the holes, and then another rectangular transparent soft material is stacked on the precise filter screen 7. Then, an input connector 1, a dosing connector 3 and an exhaust pipe 2 are welded (or compounded) and fixed at one end of the transparent soft material in the length direction, an output connector 6 is welded (or compounded) and fixed at the other end of the transparent soft material, and after the end connector on the width of one filter bag 4 is welded (or compounded), the width of the next group of filter bags 4 is welded (or compounded) until the whole rectangular transparent material is welded (or compounded). Finally, the contour of each filter bag 4 is formed by high-frequency hot welding according to the size of the single filter bag 4, sealing is carried out, and the production process is finished after the machine cutting is carried out. The whole production process is realized by mechanical automation, batch production can be realized, manual assembly is not needed in the production process, the production efficiency is improved, and the product percent of pass is improved.
When in use, the invention can be used for filtering liquid medicine, is arranged at the lower end of a transfusion tube, can also be used for filtering salt water and is directly arranged on a water outlet of a salt water bag. Is small and practical, and is simple and convenient to use.
The above description is only a preferred embodiment of the present invention, and is not intended to limit the scope of the present invention, and all equivalent changes and modifications made within the scope of the present invention should be considered as the technical scope of the present invention.
Claims (5)
1. The manufacturing method of the soft polymer precision filter for transfusion is characterized by comprising the following steps:
uniformly arranging a row of exhaust holes (5) on a transparent soft material, and then compounding water-blocking films (8) on the corresponding exhaust holes (5) to form a bottom film; then compounding corresponding end joints in the width direction of the bottom film, wherein each end joint comprises an input joint (1), a dosing joint (3) and an exhaust pipe (2);
a row of vent holes (5) are uniformly formed in the other transparent soft material, and then water-blocking films (8) are compounded on the corresponding vent holes (5) to form a mask; then compounding a corresponding end joint in the width direction of the facial mask, wherein the end joint comprises an output joint (6);
sequentially arranging a filter membrane (10) and a lining membrane (11) on a silk screen (9) and compounding into a long-strip structure, and cutting a precise filter screen (7) with corresponding size according to the length and width of the base membrane and the face membrane;
stacking a precise filter screen (7) on the basement membrane, and then stacking the facial mask on the precise filter screen (7), wherein the side of the silk screen (9) faces the basement membrane; then integrally welding or high-frequency heat welding a plurality of arranged filter bags by ultrasonic waves according to the outline size of the single filter bag (4), and finally cutting by a machine to finish the mass production process of the filter bags;
the soft material high polymer precision filter comprises a filter bag (4) made of a light film material, wherein a filter cavity and a liquid discharge cavity are formed in the filter bag (4) by arranging a precision filter screen (7); the upper end of the filter bag (4) is provided with an input joint (1) and a dosing joint (3), and the input joint (1) and the dosing joint (3) are both communicated with the liquid discharge cavity; the lower end of the filter bag (4) is provided with an output joint (6), and the output joint (6) is communicated with the liquid discharge cavity;
the precise filter screen (7) comprises a silk screen (9), a filter membrane (10) and a lining membrane (11), wherein the silk screen (9) is arranged close to one side of the liquid discharge cavity, the filter membrane (10) is arranged on the silk screen (9), the lining membrane (11) covers the filter membrane (10), and the lining membrane (11) is arranged close to one side of the filter cavity; the precise filter screen (7) is arranged between two side walls of the filter bag (4) and is integrally welded by ultrasonic waves or formed by high-frequency hot welding.
2. The soft polymer precision filter for transfusion manufactured by the manufacturing method according to claim 1, characterized in that: the filter membrane (10) is a nuclear microporous filter membrane, a polyether sulfone membrane, a polyester membrane or a nylon membrane; the lining film (11) is a fiber film, a nylon film or a polyester film.
3. The soft polymer precision filter for infusion as claimed in claim 2, wherein: the filtering aperture of the filter membrane (10) is 1.2-15 microns.
4. The soft polymer precision filter for transfusion manufactured by the manufacturing method according to claim 1, characterized in that:
before the exhaust hole (5) is not used, an air film for sealing the exhaust hole (5) is arranged on the exhaust hole (5).
5. The soft polymer precision filter for transfusion manufactured by the manufacturing method according to claim 1, characterized in that: the input connector (1) and the output connector (6) are both luer connectors or quick connectors; the filter bag (4) is made of a medical transparent soft material.
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CN201710039624.8A CN106621510B (en) | 2017-01-19 | 2017-01-19 | Soft material polymer precision filter for transfusion and manufacturing method thereof |
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CN201710039624.8A CN106621510B (en) | 2017-01-19 | 2017-01-19 | Soft material polymer precision filter for transfusion and manufacturing method thereof |
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CN106621510B true CN106621510B (en) | 2022-09-27 |
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Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
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CN107158523A (en) * | 2017-05-26 | 2017-09-15 | 河南曙光健士医疗器械集团股份有限公司 | A kind of syringe uses decoction macromolecule accurate filter |
CN109092074A (en) * | 2018-08-09 | 2018-12-28 | 常州费曼生物科技有限公司 | Silicon-on-insulator material infusion filter membrane and preparation method thereof, filter and infusion apparatus |
CN109092077A (en) * | 2018-08-09 | 2018-12-28 | 常州费曼生物科技有限公司 | Silicon nitride material infusion filter membrane and preparation method thereof, filter and infusion apparatus |
CN109092076A (en) * | 2018-08-09 | 2018-12-28 | 常州费曼生物科技有限公司 | Monocrystalline silicon material precision transfusion filter membrane and preparation method thereof, filter and infusion apparatus |
CN109092075B (en) * | 2018-08-09 | 2020-07-10 | 常州费曼生物科技有限公司 | Precision transfusion filter membrane and preparation method thereof, precision transfusion filter membrane structure and preparation process thereof, precision transfusion filter and transfusion device |
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CA1027495A (en) * | 1973-08-13 | 1978-03-07 | Paul R. Henri | Bag filter support cage |
CN2061480U (en) * | 1989-12-13 | 1990-09-05 | 潍坊市人民医院 | Drum finely filtering device |
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