WO2019024827A1

WO2019024827A1 - Precision medicinal solution filter

Info

Publication number: WO2019024827A1
Application number: PCT/CN2018/097643
Authority: WO
Inventors: 付渊; 元彰; 张溢波; 姬志峰; 荆春喜
Original assignee: 西安互邦过滤膜新材料科技有限公司; 郑州康佳医疗器械有限公司
Priority date: 2017-07-31
Filing date: 2018-07-27
Publication date: 2019-02-07
Also published as: CN107469196B; CN107469196A

Abstract

A precision medicinal solution filter comprising: a filter body (1) provided within a syringe (2) or connected to a needle base of the syringe (2). The front extremity of the filter body (1) is a conical extremity (6); the rear extremity is a filter extremity (5). The filter body (1) comprises a filter block (8) and a floating plug (7) movably provided within the filter block (8). A filter cavity is formed inside the filter block (8). An annular filter membrane (9) is provided within the filter cavity. When the syringe is drawing a solution, the floating plug (7) moves to the top part of a floating plug channel (81) of the filter block (8), the solution enters the filter cavity via a blind hole (71) of the floating plug (7). When the syringe is discharging the solution, the floating plug (7) moves away from the top part of the floating plug channel (81) of the filter block (8). The solution of the filter cavity enters the blind hole (71) of the floating plug (7) via the annular filter membrane (9) and a peripheral channel of the filter block (8). The filter is inexpensive, filters safely, is convenient to use, and, during a dosing process, allows microparticles and sediments to be filtered directly when preparing the solution, thus achieving the effect of precision filtration and ensuring medicament use safety for a patient.

Description

Precision chemical liquid filter

Technical field

The invention relates to the technical field of medical instruments, in particular to a precision medical liquid filter.

Background technique

With the continuous improvement of modern medical level and people's material living standards, the harm of clinical drug insoluble particles to the human body has been widely recognized by medical workers. At the same time, some patients also have various ways to harm the insoluble particles in the liquid. Recognizing that they are increasingly aware of the quality and safety of clinical medications, and their requirements are getting higher and higher. However, the syringes used in clinical practice on the domestic market do not have the function of filtering insoluble particles in the drug solution, and a large amount of insoluble particles in the drug solution are injected into the blood of the human body together with the drug solution. Larger (larger than the diameter of the blood vessels, generally 6-8 μm for adults; children, especially infants and young children with capillaries generally up to 2 ~ 3 μm), can directly cause local circulatory disorders, causing partial clogging and insufficient oxygen supply. Tissue hypoxia produces edema and inflammation; blood flow less than this diameter can directly cause thrombosis or due to foreign matter invading the tissue, causing red blood cells to accumulate around the particles to increase the volume, resulting in granuloma, and due to the large number of blood vessels can also cause embolism. In the modern age, especially infants and children, the risk is greater, because the human capillaries are generally 6-8 μm, and the capillaries of children, especially infants, are generally 2 to 3 μm. It is conceivable that infants and children are receiving medication. How much security risk it bears. However, there is currently no simple and feasible filter for liquid filtration.

Summary of the invention

In order to solve the technical defect problem existing in the prior art syringe, the present invention provides a precision medical liquid filter. The syringe is not only low in cost, safe in filtration, and convenient to use. During the dosing process, it directly filters particles and precipitates when formulating a liquid, thereby achieving the effect of precision filtration and ensuring patient safety.

In order to achieve the above object, the present invention adopts the following technical means:

A precision chemical liquid filter comprising: a filter body disposed inside or connected to a syringe needle hub, the filter body front end having a tapered end and a rear end being a filter end; the filter The body comprises a filter block and a floating plug disposed inside the filter block, a filter cavity is formed inside the filter block, and an annular filter membrane is arranged in the filter cavity; when the syringe is pumped, the float plug moves to the top of the float channel of the filter block, and the liquid is from The blind hole of the floating plug enters the filtering chamber; when the syringe is drained, the floating plug is away from the top of the floating plug channel of the filter block, and the liquid of the filtering chamber passes through the annular filtering membrane and the peripheral passage of the filter block to enter the blind hole of the floating plug.

The floating plug is a boss structure, and a blind hole is arranged along the axis thereof. The side wall of the boss on the floating plug is provided with a liquid outlet hole and a liquid inlet hole communicating with the blind hole; the filter block is provided with a floating plug The shape matching floating plug channel, the small end of the floating plug channel is connected with the filtering chamber, and the filtering chamber is provided with an annular filtering membrane except the small end outlet of the floating plug channel; the filter block is also provided with a connecting filter chamber and a large end of the floating plug channel The liquid passage; when the floating plug shoulder and the floating plug channel are in close contact, the blind hole communicates with the filter chamber through the liquid inlet hole, and the liquid outlet hole and the liquid outlet channel are in a sealed state; when the floating plug shoulder and the floating plug channel are in a gap setting The blind hole communicates with the filter chamber through the liquid outlet hole and the liquid outlet channel, and the liquid inlet hole is in a sealed state.

The outlet channels are pluralityed and disposed along the axis of the filter block.

The liquid outlet hole and the liquid inlet hole are evenly distributed along the circumferential direction of the float.

When the filter body is coupled to the syringe needle hub, the connection end of the filter end is coupled to the needle holder, the attachment hole is matched to the shape of the outer wall of the needle holder, and the tapered end is for connection with the needle.

When the filter body is disposed inside the syringe, the filter body has a size matching the inner cavity of the front end of the syringe, the tapered end is inserted into the inner cavity of the needle holder, and the inner wall of the syringe is sealingly connected with the filter body.

The filter end lumen matches the shape of the piston at the front end of the injection rod.

The annular filter membrane is a nuclear microporous membrane, a polyethersulfone membrane, a polyester membrane or a nylon membrane.

The annular filtration membrane has a filtration pore size of 1.2 to 15 microns.

The needle seat and the tapered end are threaded joints or push-in fittings.

Compared with the prior art, the present invention has the following advantages:

The chemical liquid precision floating plug filter of the invention can be used for the syringe or can be placed in the syringe, and is used for filtering the liquid medicine by using the same with the syringe. The filtering device comprises a filter block and a floating device arranged inside the filter block. Plug, when the syringe is pumping, the float plug moves to the top of the float channel of the filter block, and the liquid enters the filter chamber from the blind hole in the center of the float plug. When the syringe drains, the float plug is away from the top of the float channel of the filter block, and the filter is filtered. The liquid in the cavity passes through the annular filter membrane and the peripheral passage of the filter block enters the blind hole of the floating plug. Thereby, the function of pumping without filtering and draining filtration is realized. The built-in filtering device of the present invention does not cause other workload to the user, and the liquid medicine is filtered while being used normally. Not only low cost, safe filtration, easy to use, during the dosing process, particles and precipitates that are difficult to detect by the naked eye are injected into the infusion bottle (bag) with the needle of the syringe, which causes safety hazards in the infusion, and the precision infusion device is used to filter the particles. The high cost makes it possible to directly filter particles and precipitates when formulating liquids, achieving the effect of precision filtration and ensuring patient safety.

Further, the floating plug is a boss structure, and the filter block is provided with a floating plug channel matching the shape of the floating plug. When the floating plug shoulder and the floating plug channel are in close contact, the blind hole communicates with the filtering cavity through the liquid inlet hole, and the liquid is discharged. The hole and the liquid outlet channel are in a sealed state; when the gap between the floating plug shoulder and the floating plug channel is set, the blind hole communicates with the filter chamber through the liquid outlet hole and the liquid outlet channel, and the liquid inlet hole is in a sealed state. Compared with ordinary syringes, it is easy to operate, easy to use, and has a filtering function.

Further, the advantage of the center setting of the liquid outlet channel is that the liquid medicine is easily discharged when the center is squeezed, the liquid discharge force is small, and the filtration is sufficient. The symmetric distribution of the center of the inlet channel facilitates shunting into the syringe during pumping, and the pumping efficiency is high.

Further, the filter body inside the syringe is a combined structure; it can be separately manufactured at the time of manufacture, and combined in use, which is convenient for manufacture and transportation.

DRAWINGS

1 is a schematic view of a precision float filter of Embodiment 1;

Figure 2 is a state diagram of the use of the precision float filter;

3 is a schematic view of a precision float filter of Embodiment 2;

Figure 4 is a state diagram of the use of the precision float filter;

Figure 5 is a schematic view of a floating plug;

Figure 6 is a schematic view of a filter block;

Figure 7 is a cross-sectional view of the filter block along A-A;

Figure 8 is a schematic diagram of the filter body;

Wherein, 1 is the filter body; 2 is the syringe; 3 is the injection rod; 4 is the piston; 5 is the filter end; 6 is the tapered end; 7 is the floating plug; 71 is the blind hole; 72 is the liquid outlet, 73 For the inlet hole, 8 is the filter block, 81 is the float channel, and 82 is the outlet channel.

Detailed ways

The invention is further illustrated by the following figures and specific embodiments, which are not limited to the following embodiments.

Example 1

As shown in FIG. 1 and FIG. 2, a precision floating plug filter for a syringe of the present invention comprises: a filter body 1, a front end of the filter body 1 is a tapered end 6 for connecting a needle, and a rear end is used for The filter body 5 is connected to the filter end 5 of the syringe holder 4; the filter body 1 includes a filter block 8 and a floating plug 7 movably disposed inside the filter block 8, a filter chamber is formed inside the filter block 8, and an annular filter membrane 9 is disposed in the filter chamber; When the syringe is pumping, the float 7 moves to the top of the float channel 81 of the filter block 8, and the liquid enters the filter chamber from the blind hole 71 of the float 7. When the syringe drains, the float 7 is away from the float of the filter block 8. At the top of the channel 81, the liquid in the filter chamber passes through the annular filter membrane 9, and the peripheral passage of the filter block 8 enters the blind hole 71 of the float plug 7.

As shown in FIG. 5 to FIG. 8 , the floating plug 7 is a boss structure, and a blind hole 71 is disposed along the axis thereof. The side wall of the boss on the floating plug 7 is provided with a liquid outlet hole 72 and a liquid inlet hole communicating with the blind hole 71. 73; a filter plug 8 is provided with a float plug channel 81 matching the shape of the float plug 7, the small end of the float plug passage 81 is connected with the filter chamber, and the filter chamber is provided with an annular filter membrane 9 except for the small end outlet of the float plug passage 81; The filter block 8 is further provided with a liquid outlet passage 82 connecting the filter chamber and the large end of the float passage 81; when the shoulder of the float plug 7 is in close contact with the float passage 81, the blind hole 71 communicates with the filter chamber through the liquid inlet hole 73. The liquid outlet hole 72 and the liquid outlet channel 82 are in a sealed state; when the floating plug 7 shoulder is disposed in the gap between the floating plug channel 81, the blind hole 71 communicates with the filter chamber through the liquid outlet hole 72 and the liquid outlet channel 82, and the liquid inlet hole 73 It is in a sealed state.

Example 2

As shown in FIG. 3 and FIG. 4 , a precision floating plug filter for a syringe includes: a filter body 1 , the filter body 1 is disposed inside the syringe 2 , and the size and shape of the filter body 1 and the syringe 2 The front end cavity is matched, the tapered end 6 is inserted into the inner cavity of the needle holder 4, and the inner wall of the syringe 2 is sealingly connected with the filter body 1. The inner cavity of the filter end 5 matches the shape of the piston at the front end of the injection rod 3.

The filter body 1 comprises a filter block 8 and a floating plug 7 disposed inside the filter block 8. The filter block 8 forms a filter chamber inside, and an annular filter membrane 9 is arranged in the filter chamber; when the syringe is pumped, the float 7 moves to the filter. At the top of the float channel 81 of the block 8, liquid enters the filter chamber from the blind hole 71 of the float 7. When the syringe is drained, the float 7 is away from the top of the float channel 81 of the filter block 8, and the liquid in the filter chamber passes through the annular filter membrane. 9. The peripheral passage of the filter block 8 enters the blind hole 71 of the float 7.

The filtration membrane 1-3 is a medical grade material such as a nuclear microporous membrane, a polyethersulfone membrane, a polyester membrane or a nylon membrane; and the filtration membrane 1-3 has a filtration pore size of 1.2 to 15 μm.

To facilitate the use of different needles, the needle hub is a threaded joint or a push-in fitting.

As shown in FIG. 2 and FIG. 8, when the present invention is used, the filter device end 1 is screwed to the syringe 2, and the injection rod 3 is inserted into the syringe 2, so that the liquid medicine can be configured and can be performed. The liquid is precisely filtered. First, the injection rod 3 is removed from the syringe 2, and the filter device end 1 is loaded into the syringe 2, pushed to the bottom, and finally the injection rod 3 is inserted into the syringe 2, and the liquid medicine can be configured. And can carry out precision filtration of liquid medicine. When the injection rod 3 is pulled outward to move the liquid, the syringe 2 generates a negative pressure, and the liquid medicine enters the blind hole 71 of the floating plug 7 from the needle under the action of the negative pressure, and the shoulder of the floating plug 7 is attached to the floating plug channel 81. When it is tight, the blind hole 71 communicates with the filter chamber through the liquid inlet hole 73, and the liquid outlet hole 72 and the liquid outlet channel 82 are in a sealed state; the liquid medicine can only be connected through several blind holes 71, the liquid inlet hole 73 and the filter cavity. The liquid is pumped into the syringe 2. When the squeeze injection rod 3 is moved inwardly to discharge liquid, the chemical liquid is first filtered through the annular filter membrane 9, and then enters the blind hole 71 through the liquid outlet passage 82 to be discharged. The entire operation did not cause other workload to the user, and the liquid medicine was filtered while being used normally.

As shown in FIG. 4 and FIG. 8, when the present invention is used, the injection rod 3 is first removed from the syringe 2, the filter device 1 is loaded into the syringe 2, and pushed to the bottom, and finally the injection rod 3 is inserted. In the syringe 2, the liquid medicine can be disposed, and the chemical liquid can be precisely filtered. When the injection rod 3 is pulled outward to move the liquid, the syringe 2 generates a negative pressure, and the liquid medicine enters the blind hole 71 of the floating plug 7 from the needle under the action of the negative pressure, and the shoulder of the floating plug 7 is attached to the floating plug channel 81. When it is tight, the blind hole 71 communicates with the filter chamber through the liquid inlet hole 73, and the liquid outlet hole 72 and the liquid outlet channel 82 are in a sealed state; the liquid medicine can only be connected through several blind holes 71, the liquid inlet hole 73 and the filter cavity. The liquid is pumped into the syringe 2. When the squeeze injection rod 3 is moved inwardly to discharge liquid, the chemical liquid is first filtered through the annular filter membrane 9, and then enters the blind hole 71 through the liquid outlet passage 82 to be discharged. The entire operation did not cause other workload to the user, and the liquid medicine was filtered while being used normally.

The above is only the preferred embodiment of the present invention, and is not intended to be limited to the scope of the present invention. The equivalent changes and modifications made by the content of the invention are intended to be the technical scope of the present invention.

Claims

A precision chemical liquid filter, comprising: a filter body (1) disposed inside a syringe barrel (2) or connected to a syringe barrel (2) needle holder (4), the filter body ( 1) The front end is a tapered end (6), and the rear end is a filter end (5); the filter body (1) includes a filter block (8) and a floating plug (7) that is disposed inside the filter block (8). a filter chamber is formed inside the filter block (8), and an annular filter membrane (9) is arranged in the filter chamber; when the syringe is pumped, the float plug (7) moves to the top of the float passage (81) of the filter block (8). The liquid enters the filter chamber from the blind hole (71) of the float (7); when the syringe is drained, the float (7) is away from the top of the float channel (81) of the filter block (8), and the liquid in the filter chamber is filtered through the ring. The peripheral passage of the membrane (9) and the filter block (8) enters the blind hole (71) of the floating plug (7).
A precision medical liquid filter according to claim 1, wherein said floating plug (7) is a boss structure, and a blind hole (71) is provided along the axis thereof, and the floating plug (7) is provided. The side wall of the boss is provided with a liquid outlet hole (72) and a liquid inlet hole (73) communicating with the blind hole (71); the filter block (8) is provided with a floating plug channel matching the shape of the floating plug (7) ( 81), the small end of the floating plug channel (81) is in communication with the filter chamber, and the filter chamber is provided with an annular filter membrane (9) except for the small end outlet of the float plug passage (81); the filter block (8) is also provided with a connected filter The outlet passage (82) at the large end of the chamber and the float passage (81); when the float (7) shoulder is in close contact with the float passage (81), the blind hole (71) passes through the inlet (73) and is filtered. The cavity is connected, the liquid outlet hole (72) and the liquid outlet channel (82) are in a sealed state; when the floating plug (7) shoulder is disposed in the gap between the floating plug channel (81), the blind hole (71) passes through the liquid outlet hole (72). The liquid outlet channel (82) is in communication with the filter chamber, and the liquid inlet hole (73) is in a sealed state.
A precision medical liquid filter according to claim 2, wherein said plurality of liquid outlet passages (82) are provided along the axis of the filter block (8).
A precision chemical liquid filter according to claim 2, wherein said liquid outlet hole (72) and said liquid inlet hole (73) are uniformly distributed circumferentially along the floating plug (7).
A precision chemical liquid filter according to claim 1, characterized in that the connection of the filter end (5) when the filter body (1) is connected to the syringe holder (2) needle holder (4) The hole is connected to the needle holder (4), the connection hole is matched to the shape of the outer wall of the needle holder (4), and the tapered end (6) is for connection with the needle.
A precision medical fluid filter according to claim 1, characterized in that the filter body (1) is sized and injected when the filter body (1) is disposed inside the syringe (2) The inner cavity of the front end of the cylinder (2) is matched, the tapered end (6) is inserted into the inner cavity of the needle seat (4), and the inner wall of the syringe (2) is sealingly connected with the filter body (1).
A precision medical fluid filter according to claim 6, characterized in that the inner end of the filter end (5) matches the shape of the piston at the front end of the injection rod (3).
A precision chemical liquid filter according to claim 1, wherein said annular filtration membrane (9) is a nuclear microporous membrane, a polyethersulfone membrane, a polyester membrane or a nylon membrane.
A precision chemical liquid filter according to claim 8, wherein said annular filtration membrane (9) has a filtration pore size of 1.2 to 15 μm.
A precision medical fluid filter according to claim 1, wherein said needle holder (4) and tapered end (6) are threaded joints or push-in fittings.