CN106620621A - Colla corii asini composition for treating uterus cold and preparation method of colla corii asini composition - Google Patents

Colla corii asini composition for treating uterus cold and preparation method of colla corii asini composition Download PDF

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Publication number
CN106620621A
CN106620621A CN201710024772.2A CN201710024772A CN106620621A CN 106620621 A CN106620621 A CN 106620621A CN 201710024772 A CN201710024772 A CN 201710024772A CN 106620621 A CN106620621 A CN 106620621A
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parts
donkey
hide gelatin
cold
corii asini
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伊成龙
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Shandong Chang Ye Trade Co Ltd
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Shandong Chang Ye Trade Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/14Alkali metal chlorides; Alkaline earth metal chlorides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/235Foeniculum (fennel)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/52Juglandaceae (Walnut family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738Rosa (rose)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/754Evodia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9064Amomum, e.g. round cardamom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

The invention discloses a colla corii asini composition for treating uterus cold and a preparation method of the colla corii asini composition, and belongs to the technical field of health-care food. The colla corii asini composition is prepared from the following raw materials in parts by weight: 1 to 3 parts of cinnamon, 1 to 3 parts of fennel, 1 to 3 parts of fructus amomi, 1 to 3 parts of rose flowers, 1 to 3 parts of raw gingers, 5 to 20 parts of honey, 10 to 20 parts of black sesames, 10 to 20 parts of walnuts, 10 to 70 parts of colla corii asini and 10 to 70 parts of yellow wine. The colla corii asini composition for treating the uterus cold is relatively good in treating effect on infertility, easy abortion, irregular menstruation, dysmenorrhea, cold hands and feet, dizziness, sallow complexion, palpitation and hidrosis, takes quick response, and does not have side effects.

Description

Cold donkey-hide gelatin composition in treatment palace and preparation method thereof
Technical field
Cold donkey-hide gelatin composition in treatment palace and preparation method thereof, belongs to technical field of health care food.
Background technology
The pathological phenomenon that qi-blood deficiency described in the traditional Chinese medical science refers to oligemia or blood matter is not normal or blood function is not normal.Typically recognize For causing the cause of disease of the deficiency of blood has weakness of the spleen and the stomach, dietary deficiency, excessive blood loss, kidney qi virtual loss, work excessively etc..So-called palace is trembled with fear, and is Refer to women's insufficiency of the kidney yang, uterus lost in warm occurred lower abdomen falling inflation, pain obtains hot, relaxes, leukorrhea is more, dysmenorrhoea, menstruation Imbalance, deep tense pulse, many Tianjin of thin white fur of tongue are main symptom, and the cold cause of disease in palace mostly is to be suffered from cold in dressing and suffers from cold, covets cool on diet Drink cold, quick weight-lossing, miscarriage or excessive blood loss, kidney qi virtual loss, work excessively.
Applicant has found under study for action:Palace is trembled with fear and qi-blood deficiency, is the common disease for perplexing people, and above illness is to patient Work and life bring larger pain.In prior art to adopt drug therapy, its treatment cycle is longer, medical expense is held high more There is toxic and side effect expensive, medicine more, and cure rate and efficient relatively low, illness is difficult to effect a radical cure.
The content of the invention
The technical solution adopted for the present invention to solve the technical problems is:The cold donkey-hide gelatin composition in the treatment palace, its feature It is to be made up of the raw material of following weight portion:1 ~ 3 part of Chinese cassia tree, 1 ~ 3 part of fennel seeds, 1 ~ 3 part of fructus amomi, 1 ~ 3 part of rose, ginger 1 ~ 3 parts, 5 ~ 20 parts of honey, 10 ~ 20 parts of Semen sesami nigrum, walnut 10 ~ 20,10 ~ 70 parts of donkey-hide gelatin, 10 ~ 70 parts of yellow rice wine.
The cold donkey-hide gelatin composition in the treatment palace, it is characterised in that including the raw material of following weight portion:2 parts of Chinese cassia tree, fennel seeds 2 parts, 2 parts of fructus amomi, 2 parts of rose, 2 parts of ginger, 7 ~ 10 parts of honey, 16 ~ 17 parts of Semen sesami nigrum, walnut 13 ~ 14,20 ~ 40 parts of donkey-hide gelatin, 20 ~ 40 parts of yellow rice wine.
The cold donkey-hide gelatin composition in the treatment palace, also including the raw material of following weight portion:1 ~ 3 part of Radix Angelicae Sinensis, 1 ~ 3 part of evodia rutaecarpa With 10 ~ 20 parts of amethyst.
The preparation method of the cold donkey-hide gelatin composition in the treatment palace, it is characterised in that comprise the following steps:
1)The mixing of Chinese cassia tree, fennel seeds, fructus amomi, rose and ginger, adds water, 90 ~ 95 DEG C of circumfluence distillations 2 ~ 3 times, every time 2 ~ 3h, Filter and merge extract, concentrate, be dried, crush to obtain extract powder;
2)Donkey-hide gelatin is weighed by weight ratio, extract powder is added, yellow rice wine and soaking in Mel dissolving is poured into, obtains mixed liquor;
3)Hot mixing liquid is boiled, slow fire is boiled in sticky lotion, adds Semen sesami nigrum and walnut, stirred, in pouring mould into, Cooling, obtains colla corii asini cake.
The preparation method of the cold donkey-hide gelatin composition in the treatment palace, it is characterised in that comprise the following steps:
1)The mixing of Chinese cassia tree, fennel seeds, fructus amomi, rose and ginger, adds water, 90 ~ 95 DEG C of circumfluence distillations 2 ~ 3 times, every time 2 ~ 3h, Filter and merge extract, concentrate, be dried, crush to obtain extract powder;
2)Donkey-hide gelatin is weighed by weight ratio, pours yellow rice wine and soaking in Mel dissolving, concentration, dry gelatin powder into;
3)Semen sesami nigrum and walnut are weighed by weight ratio, and stirring mixing was crushed 100 ~ 500 mesh sieves and obtains fine powder;By extract powder, Gelatin powder and fine powder mix, and obtain donkey-hide gelatin electuary.
Applicant is described as follows for the present invention's:
Chinese cassia tree, taste is pungent, sweet, big heat.Return kidney, spleen, the heart, Liver Channel.Indication:Mends fire supporing yang, let the fire back to its origin, eliminating cold to stop pain is living Blood stimulates the menstrual flow.For impotence, Gong Leng, waist and knee crymodynia, kidney deficiency is breathed heavily, dizziness due to yang deficiency, hot eyes pharyngalgia, trusted subordinate's crymodynia, cold of insufficiency type vomiting and diarrhea, is trembled with fear Hernia, run quickly globefish, Amenorrhea, dysmenorrhoea.
Fennel seeds, taste is pungent, temperature.Return liver,kidney,spleen, stomach.Indication:Eliminating cold to stop pain, regulating qi-flowing for harmonizing stomach, sharp liver and gall, sterilization Anti-inflammatory.For cold hernia stomachache, the testis swelling and hanging down of either of the testes, dysmenorrhoea, few abdomen crymodynia, abdominal distention, deficiency of food is vomited and diarrhoea, hydrocele testis.Salt is little The warm kidney eliminating cold to stop pain of fennel.For cold hernia stomachache, the testis swelling and hanging down of either of the testes, the cold stomachache of Jing.
Fructus amomi, taste is pungent, temperature.Returns spleen, stomach, kidney channel.Indication:Dampness elimination appetizing, warming spleen and stopping diarrha, regulates the flow of vital energy antiabortive.For wet Turbid middle resistance, gastral cavity ruffian is not hungry, deficiency-cold in spleen and stomach, vomiting is had loose bowels, pernicious vomiting, fetal irritability.
Rose, sweet, slight bitter, temperature.Return liver, the spleen channel.Indication:Promoting qi circulation and removing obstruction in the collateral, and blood, pain relieving.For liver stomach Qi Bitterly, deficiency of food evil of vomitting, irregular menstruation, the pain of injury caused by falling and tumbling.Pharmacological action:Rose wate decoction can release the toxicity of oral antimony agent(It is little Mouse).But only it is limited with tartar emetic oral medication, and the anti-schistosome function of tartar emetic is also released with toxicity and disappeared.
Ginger, pungent, tepor is nontoxic.Middle benefit gas of coughing are controlled, turgor is controlled, cholera is more than, and stomachache, cold dysentery, blood is closed.Sufferer it is empty and It is cold, preferably in addition.Ginger is considered to be worth doing, and wine clothes, controls inclined wind.The medicine of lung channel gas point, can beneficial lung.
Honey, it is sweet, put down, it is nontoxic.Spleen;Stomach;Lung;Large intestine channel.Bowl spares is moisturized, pain relieving, removing toxic substances.Trusted subordinate's perverse trend, all frightened epilepsies, Five viscera settling various symptims and signs of deficiency, invigorating middle warmer and replenishing QI, analgesic antidotal, except many diseases, and hundred medicines.Long term usage, strong will is made light of one's life by commiting suicide, not hungry not old, macrobiosis god It is celestial.Foster temper, except vexed, inappetence, only intestines, pain in flesh, aphtha, bright knowledge.Tooth infantile malnutrition due to digestive disturbances or intestinalparasites, lip sore, the red barrier of mesh skin, Desinsection.Control pained and dysentery, informal dress face such as premium;Soup fire is applied, taste are adjusted.Honey is with the addition of in the present invention not only there is bowl spares The effect moisturize, detoxified can also be obviously improved
Evodia rutaecarpa, taste is pungent, hardship, heat;It is slightly poisonous.Return liver, spleen, stomach, kidney channel.Indication:Eliminating cold to stop pain, stopping nausea and vomiting by lowering the adverse flow of QI is supporing yang Antidiarrheal.For jueyin headache, cold hernia stomachache, the disturbance of lower legs due to pathogenic cold and dampness, dysmenorrhea, abdominal distention, acid regurgitation is vomitted, Diarrhoea is controlled outward Aphtha;Hypertension.
Amethyst, sweet, temperature.The thoughts of returning home, lung, kidney channel.Indication:Tranquilizing mind, warm lung warms up palace.For insomnia and dreamful sleep, Palpitation and being susceptible to fright, deficiency syndrome of the lung cough and asthma, fertility.
Semen sesami nigrum, is the black seeds of Pedaliaceae sesame, containing substantial amounts of fat and protein, also containing carbohydrate, dimension life Plain A, vitamin E, lecithin, trace element(Calcium, iron, chromium).There are stomach invigorating, liver protection, promote red blood cell growth, while can To increase internal melanin, be conducive to natural on-off cycles of hair growth.
Walnut.Nature and flavor are sweet, temperature.Return kidney, lung, large intestine channel.Indication:Kidney tonifying, warm lung, ease constipation.For soreness and weakness of waist and knees, sun Impotence is passed out semen, and the cold of insufficiency type is breathed heavily and coughed, constipation.
Date, Gan Ping is nontoxic, main trusted subordinate's perverse trend, An Zhong, supports temper, and flat stomach gas are led to nine orifices, help 12 Jing, mend few gas, Not enough in few body fluid, body, frightened, heaviness of limbs, and hundred medicines, long term usage is made light of one's life by commiting suicide macrobiosis, can make perspiration, antiallergy, except smelling as of rotten fish, strange taste, Antitoxic heart-soothing and sedative, brain healthy, whet the appetite.To prevention and cure of cardiovascular disease, acute, chronic hepatitis, cirrhosis, anaemia, anaphylactoid purpura There is preferable curative effect.Preferably, date used in the present invention is the date after stoning peeling(That is jujube meat part), the jujube of date Even if core and fructus corni Jing boiling water brew or boil boil it is broken after still hardness it is higher, mouthfeel unpolished rice when patient swallows affects to suffer from after addition The enthusiasm that person takes.
Donkey-hide gelatin, it is sweet, it is mild-natured.Return lung, liver and kidney channel.Indication:Enrich blood enriching yin, moisturize, stop blooding.For blood deficiency chlorosis, Dizziness palpitaition, flesh impotence is unable, dysphoria and insomnia, endogenous deficient wind, xeropulmonary cough, labor is coughed spitting of blood, haematemesis hematuria, uterine bleeding of having blood in stool, gestation Threatened abortion.
Yellow rice wine, it is bitter, pungent, it is warm in nature, enter liver meridian, the gallbladder channel of foot-Shaoyang.Yellow rice wine pungent-warm rise send out, homoiothermy arteries and veins and disappear it is cold puckery, Deficiency of yang fire loses, battalion defend cold stagnant person preferably it, outstanding preferably woman, therefore tire produces all sides, multiplex yellow rice wine.
When colla corii asini cake and donkey-hide gelatin electuary is prepared, step 1)Using Chinese cassia tree, fennel seeds, fructus amomi, rose and ginger are mixed Close, when Radix Angelicae Sinensis, evodia rutaecarpa and amethyst is added, step 1)Using Chinese cassia tree, fennel seeds, fructus amomi, rose, ginger, Radix Angelicae Sinensis, Wu The fruit of medicinal cornel and amethyst mix.Step 1)Amount of water need to not have mixing medicinal material;Preferably, concentration, be dried using reduced pressure concentration, 40 ~ 45 DEG C of low-temperature heats are dried or lyophilized, to prevent effective component to be destroyed because of high temperature.Step 2)Described slow fire is boiled in glutinous The concrete operations of thick paste body are:Mixed liquor is heated into 100 ~ 120 DEG C, to heating is stopped during mixed liquor moisture content 15 ~ 25%, is obtained Obtain sticky lotion.
Compared with prior art, the beneficial effect that cold donkey-hide gelatin composition in treatment palace of the invention and preparation method thereof has It is really:
1st, infertile, easy miscarriage, the menstruation that the cold donkey-hide gelatin composition in treatment palace of the invention is cold for palace, qi-blood deficiency causes is not Tune, dysmenorrhoea, ice-cold, dizzy trick, sallow complexion, nervous, hidrosis have preferable curative effect, instant effect, and have no side effect.Application People devises the donkey-hide gelatin composition that the treatment palace of the present invention is trembled with fear, and the cold donkey-hide gelatin composition in the treatment palace is taken in oral mode, Dietotherapy takes into account, and has reached therapeutic purposes, and long-term taking has no toxic side effect.Jing applicant's clinical statisticses, with 1 month as one The course for the treatment of, takes to 2 ~ 3 courses for the treatment of(2 ~ 3 months)It is effective, take to 6 courses for the treatment of(6 months)Cure, qi-blood deficiency cold for palace The cure rate of the illness of initiation reaches 80 ~ 100%, efficient to reach 85 ~ 100%.
The preparation method is simple of the cold donkey-hide gelatin composition in treatment palace the 2nd, of the invention is easy, taking convenience.Applicant designs Two kinds of different preparation methods, by the present composition make colla corii asini cake or donkey-hide gelatin electuary, have both been easy to oral edible, its preparation Method improves drug effect again.Colla corii asini cake made by the cold donkey-hide gelatin composition in treatment palace, using 90 ~ 95 DEG C of circumfluence distillations of adding water Mode is extracted to Chinese cassia tree, fennel seeds, fructus amomi, rose and ginger, obtains the extract powder rich in effective component, is both reduced The volume of medicine, the drug effect of concentration again, while improve the eating mouth feel of donkey-hide gelatin composition.
3rd, the cold donkey-hide gelatin composition in treatment palace of the invention for palace tremble with fear cause infertile have preferable curative effect.Application People has found, when formula is 1 ~ 3 part of Chinese cassia tree, 1 ~ 3 part of fennel seeds, 1 ~ 3 part of fructus amomi, 1 ~ 3 part of rose, 1 ~ 3 part of ginger, honey 5 ~ 20 When 10 ~ 70 parts of part, 10 ~ 20 parts of Semen sesami nigrum, walnut 10 ~ 20,10 ~ 70 parts of donkey-hide gelatin and yellow rice wine, for palace tremble with fear cause it is infertile Cure rate reach 85 ~ 90%, and made by colla corii asini cake and donkey-hide gelatin electuary mouthfeel it is excellent.And work as and increased 1 ~ 3 part of Radix Angelicae Sinensis, Wu After 10 ~ 20 parts of 1 ~ 3 part of the fruit of medicinal cornel and amethyst, the donkey-hide gelatin composition of the present invention treatment palace tremble with fear cause it is infertile on have protrusion Therapeutic effect, cure rate can reach 99 ~ 100%.
Specific embodiment
Embodiment 1 ~ 7 is the specific embodiment of the donkey-hide gelatin composition that the treatment palace of the present invention is trembled with fear and preparation method thereof, wherein Embodiment 1 is preferred forms.Donkey-hide gelatin used by embodiment 1 ~ 7 is 3 years of Dong-E donkey-hide Gelatin Co., Ltd., Shandong Prov.'s production Old glue.Yellow rice wine used is the burnt odor type Jimo yellow rice wine of Jimo yellow rice wine factory production.Rose is that Jinan Pingyin area produces Rosa rugosa Bud.The weight portion of raw material in embodiment and comparative example, calculates according to the dry weight of raw material.
Embodiment 1
It is made up of the raw material of following weight portion:2 parts of Chinese cassia tree, 2 parts of fennel seeds, 2 parts of fructus amomi, 2 parts of rose, 2 parts of ginger, honey 7 20 parts of part, 17 parts of Semen sesami nigrum, walnut 13,20 parts of donkey-hide gelatin and yellow rice wine;
Preparation method is as follows:
1)The mixing of Chinese cassia tree, fennel seeds, fructus amomi, rose and ginger, adds water, 90 ~ 95 DEG C of circumfluence distillations 2 ~ 3 times, every time 2 ~ 3h, Filter and merge extract, concentrate, be dried, crush to obtain extract powder;
2)Donkey-hide gelatin is weighed by weight ratio, extract powder is added, yellow rice wine and soaking in Mel dissolving is poured into, obtains mixed liquor;
3)Hot mixing liquid is boiled, slow fire is boiled in sticky lotion, adds Semen sesami nigrum and walnut, stirred, in pouring mould into, Cooling, obtains colla corii asini cake.
Embodiment 2
It is made up of the raw material of following weight portion:2 parts of Chinese cassia tree, 2 parts of fennel seeds, 2 parts of fructus amomi, 2 parts of rose, 2 parts of ginger, honey 10 Part, 16 parts of Semen sesami nigrum, walnut 14,20 parts of donkey-hide gelatin, 20 parts of yellow rice wine;
Preparation method is as follows:
1)The mixing of Chinese cassia tree, fennel seeds, fructus amomi, rose and ginger, adds water, 90 ~ 95 DEG C of circumfluence distillations 2 ~ 3 times, every time 2 ~ 3h, Filter and merge extract, concentrate, be dried, crush to obtain extract powder;
2)Donkey-hide gelatin is weighed by weight ratio, extract powder is added, yellow rice wine and soaking in Mel dissolving is poured into, obtains mixed liquor;
3)Hot mixing liquid is boiled, slow fire is boiled in sticky lotion, adds Semen sesami nigrum and walnut, stirred, in pouring mould into, Cooling, obtains colla corii asini cake.
Embodiment 3
It is made up of the raw material of following weight portion:2 parts of Chinese cassia tree, 2 parts of fennel seeds, 2 parts of fructus amomi, 2 parts of rose, 2 parts of ginger, honey 10 20 parts of part, 16 parts of Semen sesami nigrum, walnut 14,20 parts of donkey-hide gelatin, 20 parts of yellow rice wine, 3 parts of Radix Angelicae Sinensis, 1 part of evodia rutaecarpa and amethyst;
Preparation method is as follows:
1)The mixing of Chinese cassia tree, fennel seeds, fructus amomi, rose, ginger, Radix Angelicae Sinensis, evodia rutaecarpa and amethyst, adds water, 90 ~ 95 DEG C of heat backflows Extraction 2 ~ 3 times, every time 2 ~ 3h, filters and merges extract, concentrates, is dried, crushes to obtain extract powder;
2)Donkey-hide gelatin is weighed by weight ratio, extract powder is added, yellow rice wine and soaking in Mel dissolving is poured into, obtains mixed liquor;
3)Hot mixing liquid is boiled, slow fire is boiled in sticky lotion, adds Semen sesami nigrum and walnut, stirred, in pouring mould into, Cooling, obtains colla corii asini cake.
Embodiment 4
It is made up of the raw material of following weight portion:1 part of Chinese cassia tree, 3 parts of fennel seeds, 1 part of fructus amomi, 3 parts of rose, 1 part of ginger, honey 20 10 parts of part, 10 parts of Semen sesami nigrum, walnut 20,10 parts of donkey-hide gelatin and yellow rice wine;
Preparation method is as follows:
1)The mixing of Chinese cassia tree, fennel seeds, fructus amomi, rose and ginger, adds water, 90 ~ 95 DEG C of circumfluence distillations 2 ~ 3 times, every time 2 ~ 3h, Filter and merge extract, concentrate, be dried, crush to obtain extract powder;
2)Donkey-hide gelatin is weighed by weight ratio, pours yellow rice wine and soaking in Mel dissolving, concentration, dry gelatin powder into;
3)Semen sesami nigrum and walnut are weighed by weight ratio, and stirring mixing was crushed 500 mesh sieves and obtains fine powder;By extract powder, donkey-hide gelatin Powder and fine powder mix, and obtain donkey-hide gelatin electuary.
Embodiment 5
It is made up of the raw material of following weight portion:3 parts of Chinese cassia tree, 1 part of fennel seeds, 3 parts of fructus amomi, 1 part of rose, 3 parts of ginger, honey 5 Part, 20 parts of Semen sesami nigrum, walnut 10,70 parts of donkey-hide gelatin, 70 parts of yellow rice wine;
Preparation method is as follows:
1)The mixing of Chinese cassia tree, fennel seeds, fructus amomi, rose and ginger, adds water, 90 ~ 95 DEG C of circumfluence distillations 2 ~ 3 times, every time 2 ~ 3h, Filter and merge extract, concentrate, be dried, crush to obtain extract powder;
2)Donkey-hide gelatin is weighed by weight ratio, pours yellow rice wine and soaking in Mel dissolving, concentration, dry gelatin powder into;
3)Semen sesami nigrum and walnut are weighed by weight ratio, and stirring mixing was crushed 100 mesh sieves and obtains fine powder;By extract powder, donkey-hide gelatin Powder and fine powder mix, and obtain donkey-hide gelatin electuary.
Embodiment 6
It is made up of the raw material of following weight portion:2 parts of Chinese cassia tree, 2 parts of fennel seeds, 2 parts of fructus amomi, 2 parts of rose, 2 parts of ginger, honey 7 10 parts of part, 17 parts of Semen sesami nigrum, walnut 13,20 parts of donkey-hide gelatin, 20 parts of yellow rice wine, 1 part of Radix Angelicae Sinensis, 3 parts of evodia rutaecarpa and amethyst;
Preparation method is as follows:
1)The mixing of Chinese cassia tree, fennel seeds, fructus amomi, rose, ginger, Radix Angelicae Sinensis, evodia rutaecarpa and amethyst, adds water, 90 ~ 95 DEG C of heat backflows Extraction 2 ~ 3 times, every time 2 ~ 3h, filters and merges extract, concentrates, is dried, crushes to obtain extract powder;
2)Donkey-hide gelatin is weighed by weight ratio, extract powder is added, yellow rice wine and soaking in Mel dissolving is poured into, obtains mixed liquor;
3)Hot mixing liquid is boiled, slow fire is boiled in sticky lotion, adds Semen sesami nigrum and walnut, stirred, in pouring mould into, Cooling, obtains colla corii asini cake.
Embodiment 7
The formula of the present embodiment is with embodiment 1;
Preparation method is as follows:
1)The mixing of Chinese cassia tree, fennel seeds, fructus amomi, rose and ginger, adds water, 90 ~ 95 DEG C of circumfluence distillations 2 ~ 3 times, every time 2 ~ 3h, Filter and merge extract, concentrate, be dried, crush to obtain extract powder;
2)Donkey-hide gelatin is weighed by weight ratio, pours yellow rice wine and soaking in Mel dissolving, concentration, dry gelatin powder into;
3)Semen sesami nigrum and walnut are weighed by weight ratio, and stirring mixing was crushed 200 mesh sieves and obtains fine powder;By extract powder, donkey-hide gelatin Powder and fine powder mix, and obtain donkey-hide gelatin electuary.
Comparative example 1
The formula and technique of this comparative example is same as Example 1, and difference is:Chinese cassia tree, fennel seeds are not added with this comparative example.
Clinical practice is summarized
It is below the medicable illness of donkey-hide gelatin composition that the treatment palace of the present invention is cold, and the Symptoms of illness.
Qi-blood deficiency:Pale complexion, have a dizzy spell, dizziness and tinnitus, two xerophtalmias, blurring of vision or night blindness, extremity numbness, Four limbs are not warm, and muscle arteries and veins contraction, palpitation and severe palpitation, insomnia and dreamful sleep, dry skin, hair is dried-up, and dry feces, difficult urination, One or more of above symptom.
It is infertile:Referred to herein as because palace tremble with fear cause it is infertile, do not ovulate, endometrium is thin, easy miscarriage, complexion are withered Huang, gets fat from head to foot, and lower abdomen is not warmed up, and four limbs are not warm, waist soreness, one or more of above symptom.
Irregular menstruation:Referred to herein as because trembling with fear the irregular menstruation for causing in palace, menstruation color it is light and measure it is few, it is wrong during menstrual period after, OK Trans-abdominal pain, the soreness of waist or pain, two mammary swellings pain, spiritual poor, mouth are tasteless, and eating is pungent dry, one or more of above symptom.
Clinic diagnosis are reported
The usage and dosage of the donkey-hide gelatin composition that the treatment palace of the present invention is trembled with fear:Take the cold donkey-hide gelatin composition in the treatment palace of the present invention(Bag Include colla corii asini cake and donkey-hide gelatin electuary)2 times a day, each orally edible 10 ~ 15g, need to eat before meals, avoid eating anything raw or cold during taking, oil Fried, maror.1 month is a course for the treatment of, can continuously be taken between the course for the treatment of and the course for the treatment of.
The donkey-hide gelatin composition that the treatment palace that applicant obtains respectively to each embodiment is trembled with fear carries out clinic diagnosis.In order to reduce Variable, during to each embodiment clinic diagnosis, qi-blood deficiency illness choose 300 patients counted, wherein patient age 20 ~ 40 years old, men and women respectively accounted for 50%;Infertile illness is chosen 300 patients and is counted, patient age 20 ~ 35 years old, is women trouble Person, irregular menstruation illness is chosen 300 patients and is counted, and patient age 18 ~ 40 years old is female patient.Outcome measure mark It is accurate:Curative effect is divided into healing, effective and invalid according to the improvement situation of above-mentioned symptom, according to aforementioned disorders classification effective effect is used In the described course for the treatment of, total effective rate is cure rate and obvious effective rate sum.Continuously use 6 courses for the treatment of(6 months)After count each reality The case treatment effect of example is applied, the clinical treatment mode of comparative example 1 is with embodiment 1 ~ 7, and statistics is as shown in the table:
The case statistics of the cold donkey-hide gelatin composition in the treatment of 1 embodiment of table 1 palace
The case statistics of the cold donkey-hide gelatin composition in the treatment of 2 embodiment of table 2 palace
The case statistics of the cold donkey-hide gelatin composition in the treatment of 3 embodiment of table 3 palace
The case statistics of the cold donkey-hide gelatin composition in the treatment of 4 embodiment of table 4 palace
The case statistics of the cold donkey-hide gelatin composition in the treatment of 5 embodiment of table 5 palace
The case statistics of the cold donkey-hide gelatin composition in the treatment of 6 embodiment of table 6 palace
The case statistics of the cold donkey-hide gelatin composition in the treatment of 7 embodiment of table 7 palace
The case statistics of the composition of 8 comparative example of table 1
Can be seen that by table 1 ~ 8, after taking 6 courses for the treatment of, the cure rate of embodiment 1 ~ 7 reaches 80 ~ 100%, efficient to reach 85 ~ 100%, it was demonstrated that after the cold donkey-hide gelatin composition in the treatment palace for taking the present invention, substantially changing occurs most of patients in its ill disease of institute It is kind.Radix Angelicae Sinensis, evodia rutaecarpa and amethyst are with the addition of in embodiment 3 and embodiment 6, the infertile curative effect for causing of trembling with fear to women palace is obtained Must significantly improve.The donkey-hide gelatin composition of the present invention, after making colla corii asini cake and donkey-hide gelatin electuary, there is preferable curative effect.Jing applicant Statistics, in embodiment 1 ~ 7, except embodiment 3 and the mouthfeel of embodiment 6 are slightly bitter, the mouthfeel of remaining embodiment is excellent, and patient takes actively Property it is high, can adhere to taking more than 6 courses for the treatment of.
The above, is only presently preferred embodiments of the present invention, is not the restriction for making other forms to the present invention, is appointed What those skilled in the art changed possibly also with the technology contents of the disclosure above or be modified as equivalent variations etc. Effect embodiment.But it is every without departing from technical solution of the present invention content, according to the technical spirit of the present invention to above example institute Any simple modification, equivalent variations and the remodeling made, still falls within the protection domain of technical solution of the present invention.

Claims (5)

1. the cold donkey-hide gelatin composition in palace is treated, it is characterised in that including the raw material of following weight portion:1 ~ 3 part of Chinese cassia tree, fennel seeds 1 ~ 3 parts, 1 ~ 3 part of fructus amomi, 1 ~ 3 part of rose, 1 ~ 3 part of ginger, 5 ~ 20 parts of honey, 10 ~ 20 parts of Semen sesami nigrum, walnut 10 ~ 20, donkey-hide gelatin 10 ~ 70 parts, 10 ~ 70 parts of yellow rice wine.
2. the donkey-hide gelatin composition that treatment palace according to claim 1 is trembled with fear, it is characterised in that including the original of following weight portion Material:2 parts of Chinese cassia tree, 2 parts of fennel seeds, 2 parts of fructus amomi, 2 parts of rose, 2 parts of ginger, 7 ~ 10 parts of honey, 16 ~ 17 parts of Semen sesami nigrum, walnut 13 ~ 14,20 ~ 40 parts of donkey-hide gelatin, 20 ~ 40 parts of yellow rice wine.
3. the donkey-hide gelatin composition that treatment palace according to claim 1 is trembled with fear, it is characterised in that also including the original of following weight portion Material:10 ~ 20 parts of 1 ~ 3 part of Radix Angelicae Sinensis, 1 ~ 3 part of evodia rutaecarpa and amethyst.
4. the preparation method of the cold donkey-hide gelatin composition in treatment palace described in claim 1 ~ 3 any one, it is characterised in that include Following steps:
1)The mixing of Chinese cassia tree, fennel seeds, fructus amomi, rose and ginger, adds water, 90 ~ 95 DEG C of circumfluence distillations 2 ~ 3 times, every time 2 ~ 3h, Filter and merge extract, concentrate, be dried, crush to obtain extract powder;
2)Donkey-hide gelatin is weighed by weight ratio, extract powder is added, yellow rice wine and soaking in Mel dissolving is poured into, obtains mixed liquor;
3)Hot mixing liquid is boiled, slow fire is boiled in sticky lotion, adds Semen sesami nigrum and walnut, stirred, in pouring mould into, Cooling, obtains colla corii asini cake.
5. the preparation method of the cold donkey-hide gelatin composition in treatment palace described in claim 1 ~ 3 any one, it is characterised in that include Following steps:
1)The mixing of Chinese cassia tree, fennel seeds, fructus amomi, rose and ginger, adds water, 90 ~ 95 DEG C of circumfluence distillations 2 ~ 3 times, every time 2 ~ 3h, Filter and merge extract, concentrate, be dried, crush to obtain extract powder;
2)Donkey-hide gelatin is weighed by weight ratio, pours yellow rice wine and soaking in Mel dissolving, concentration, dry gelatin powder into;
3)Semen sesami nigrum and walnut are weighed by weight ratio, and stirring mixing was crushed 100 ~ 500 mesh sieves and obtains fine powder;By extract powder, Gelatin powder and fine powder mix, and obtain donkey-hide gelatin electuary.
CN201710024772.2A 2017-01-13 2017-01-13 Colla corii asini composition for treating uterus cold and preparation method of colla corii asini composition Pending CN106620621A (en)

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CN112971124A (en) * 2021-03-09 2021-06-18 甘肃黑驴王子生物科技有限公司 Donkey-hide gelatin cake with channel warming and blood nourishing functions and preparation method thereof
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CN112544753A (en) * 2020-12-02 2021-03-26 王猛 Cold-dispelling tea and preparation method thereof
CN112971124A (en) * 2021-03-09 2021-06-18 甘肃黑驴王子生物科技有限公司 Donkey-hide gelatin cake with channel warming and blood nourishing functions and preparation method thereof
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