CN106620233A - Medicament for treating diabetes mellitus in dogs and cats in adjuvant way and preparation method thereof - Google Patents

Medicament for treating diabetes mellitus in dogs and cats in adjuvant way and preparation method thereof Download PDF

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Publication number
CN106620233A
CN106620233A CN201710132278.8A CN201710132278A CN106620233A CN 106620233 A CN106620233 A CN 106620233A CN 201710132278 A CN201710132278 A CN 201710132278A CN 106620233 A CN106620233 A CN 106620233A
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root
grams
radix
percent
medicament
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郑小波
彭代国
肖榕
吴柏青
王立斌
胥辉豪
杨丽辉
杨忠明
张东彦
栾司琦
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Southwest University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/342Adenophora
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/62Nymphaeaceae (Water-lily family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718Coptis (goldthread)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/808Scrophularia (figwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8964Anemarrhena
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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Abstract

The invention discloses a medicament for treating diabetes mellitus in dogs and cats in an adjuvant way and a preparation method thereof. The medicament is prepared from the following components in percentage by weight: 5.68 percent of rhizoma coptidis, 17.05 percent of pollen, 17.05 percent of radix rehmanniae, 5.68 percent of radix ophiopogonis, 5.68 percent of anemarrhenae, 11.36 percent of radix scrophulariae, 5.68 percent of radix scutellariae, 9.09 percent of radix adenophorae, 5.68 percent of cortex lycii radices and 17.05 percent of lotus root juice. The preparation method comprises the following steps: washing the rhizoma coptidis, radix rehmanniae, radix ophiopogonis, anemarrhenae, radix scrophulariae, radix scutellariae, radix adenophorae and cortex lycii radices, and baking, drying or airing the pollen for later use; weighing 5g of rhizoma coptidis, 15g of pollen, 15g of radix rehmanniae, 5g of radix ophiopogonis, 5g of anemarrhenae, 10g of radix scrophulariae, 5g of radix scutellariae, 8g of radix adenophorae and 5g of cortex lycii radices for every dose of medicament, mixing and decocting to obtain a decoction, and adding 15g of lotus root juice to be taken together. Each dose of the medicament has no side effect; the formula and the process are simple, the cost is low, and the blood glucose of the dogs and cats can be lowered effectively after the medicament is taken for a while.

Description

A kind of auxiliary treatment dog cat diabetes medicament and preparation method thereof
Technical field
The invention belongs to pet medicine technology field, more particularly to a kind of auxiliary treatment dog cat diabetes medicament and its preparation Method.
Background technology
Diabetes are a kind of lifelong diseases, and its treatment in the middle of the pets such as dog cat is related to living-pattern preservation, various The reasonable application of medicine.Diabetes can be completely effectively effected a radical cure currently without any medicine.In traditional Chinese medicine, diabetes spp in " quenching one's thirst ", " oedema " disease category, is the card of " asthenia in origin and asthenia in superficiality, simulataneous insufficiency and excessive ", is referred to because of lung, stomach, the dirty scorching deficiency of Yin of kidney three, water paddy Thirsty many drink, rapid digestion of food and polyorexia, urinary micturition or turbid urines caused by defeated cloth is not normal and pleasantly sweet, body is gradually become thin as main spy The disease levied.When being developed simultaneously with eliminating evil with righting, clinic should be based on supplementing qi and nourishing yin, enriching yin and nourishing kidney treatment for treatment.Western modern medicine is being controlled Treat and secondary failure, large side effects are gradually shown in diabetes and not enough shortcoming is prevented and treated to chronic complicating diseases;Chinese medicine is with it Toxic and side effect is little, action temperature and persistently, have the advantages that complex treatment is acted on and can delay complication, searching hypoglycemic of can yet be regarded as One important channel of new drug.By reading substantial amounts of document, it is understood that Coptis herbaceos perennial, bitter It is cold, it is heat-clearing and damp-drying drug class Chinese medicine;Root of Chinese trichosanthes, radix rehmanniae recen can promote insulin level to raise, and Plasma Glucagon Level is reduced, so as to Blood sugar is effectively reduced, in conjunction with the curative effects such as the supplementing qi and nourishing yin in Chinese traditional treatment theory, enriching yin and nourishing kidney and modern Chinese medicine blood sugar-reduction formula Blood-sugar lowering tcm drug is commonly used in agent, has formulated exclusive prescription " ten taste blood sugar reducing liquids ":The coptis, pollen, the dried rhizome of rehmannia, the tuber of dwarf lilyturf, the wind-weed, radix scrophulariae, scutellaria, The root of straight ladybell, the root bark of Chinese wolf-berry, lotus root juice, in this, as our research medicine.
In sum, western modern medicine treatment diabetes in gradually show secondary failure, large side effects and to it is chronic simultaneously Send out the not enough shortcoming of disease preventing and treating.
The content of the invention
It is an object of the invention to provide a kind of auxiliary treatment dog cat diabetes medicament and preparation method thereof, it is intended to solve west Medicine gradually shows secondary failure, large side effects in treatment diabetes and prevents and treats not enough problem to chronic complicating diseases.
The present invention is achieved in that a kind of auxiliary treatment dog cat diabetes medicament, the treatment dog cat diabetes medicament According to percentage by weight by the coptis 5.68%, pollen 17.05%, the dried rhizome of rehmannia 17.05%, the tuber of dwarf lilyturf 5.68%, the wind-weed 5.68%, radix scrophulariae 11.36%th, the root of large-flowered skullcap 5.68%, the root of straight ladybell 9.09%, the root bark of Chinese wolf-berry 5.68% and lotus root juice 17.05% are constituted.
Another object of the present invention is to a kind of preparation method of the auxiliary treatment dog cat diabetes medicament is provided, it is described The preparation method of auxiliary treatment dog cat diabetes medicament is comprised the following steps:
Step one, first the coptis, radix rehmanniae recen, the tuber of dwarf lilyturf, the wind-weed, radix scrophulariae, the root of large-flowered skullcap, the root of straight ladybell, the root bark of Chinese wolf-berry, it is clean after, Yi Jihua Powder dries, dries or dries standby;
Step 2, the component per auxiliary carry out weighing by weight 5 grams of the coptis, 15 grams of pollen, 15 grams of the dried rhizome of rehmannia, 5 grams of the tuber of dwarf lilyturf, 5 grams of the wind-weed, 10 grams of radix scrophulariae, 5 grams of the root of large-flowered skullcap, 8 grams of the root of straight ladybell, 5 grams of the root bark of Chinese wolf-berry, are brewed into decoction after mixing plus 15 grams of lotus root juice takes.
Further, the using method of the auxiliary treatment dog cat diabetes medicament is:By the coptis, pollen, the dried rhizome of rehmannia, the tuber of dwarf lilyturf, Decoction is brewed into after the wind-weed, radix scrophulariae, the root of large-flowered skullcap, the root of straight ladybell, root bark of Chinese wolf-berry mixing, plus lotus root juice takes, one time a day gavages.
Auxiliary treatment dog cat diabetes medicament that the present invention is provided and preparation method thereof, shows from traditional doctor trained in Western medicine theory;West Doctor's viewpoint:Diabetes are the metabolic diseases being characterized with hyperglycaemia, and chronic hyperglycemia often results in various internal organs, especially eye, Kidney, neural and cardiovascular long-term damage, be one group by defect of insulin secretion and (or) infringement, insufficiency and exhaustion.But Consider from traditional Chinese medical science viewpoint:Diabetes can belong in diabetes category, and diabetes clinical manifestation is many drinks, many foods, diuresis, body disappear It is thin, or urinate pleasantly sweet, the traditional Chinese medical science thinks that its interpretation of the cause, onset and process of an illness mainly examines tax deficiency, YIN fluid deficiency, scorching inclined victory.TCM Treatment of Diabetes More with supplementing qi and nourishing yin and enriching yin and nourishing kidney as the main rules for the treatment of.The present invention has no side effect per auxiliary, can long-term taking, inventive formulation, Process is simple, it is with low cost, can effectively reduce dog cat blood sugar after taking a period of time.In order to ensure curative effect, initial stage is treated Using the method for the combination of Chinese tradiational and Western medicine, to make up the shortcoming that alone " ten taste blood sugar reducing liquids " can not take effect in a short time.
Description of the drawings
Fig. 1 is the preparation method flow chart of auxiliary treatment dog cat diabetes medicament provided in an embodiment of the present invention.
Specific embodiment
In order that the objects, technical solutions and advantages of the present invention become more apparent, with reference to embodiments, to the present invention It is further elaborated.It should be appreciated that specific embodiment described herein is not used to only to explain the present invention Limit the present invention.
The application principle of the present invention is explained in detail below in conjunction with the accompanying drawings.
Auxiliary treatment dog cat diabetes medicament provided in an embodiment of the present invention is according to percentage by weight by the coptis 5.68%, flower Powder 17.05%, the dried rhizome of rehmannia 17.05%, the tuber of dwarf lilyturf 5.68%, the wind-weed 5.68%, radix scrophulariae 11.36%, the root of large-flowered skullcap 5.68%, the root of straight ladybell 9.09%th, the root bark of Chinese wolf-berry 5.68% and lotus root juice 17.05% are constituted.
As shown in figure 1, the preparation method of auxiliary treatment dog cat diabetes medicament provided in an embodiment of the present invention is including following Step:
S101:First the coptis, radix rehmanniae recen, the tuber of dwarf lilyturf, the wind-weed, radix scrophulariae, the root of large-flowered skullcap, the root of straight ladybell, the root bark of Chinese wolf-berry, it is clean after, and pollen Dry, dry or dry and be standby;
S102:Component per auxiliary carries out weighing by weight 5 grams of the coptis, 15 grams of pollen, 15 grams of the dried rhizome of rehmannia, 5 grams of the tuber of dwarf lilyturf, knows Female 5 grams, 10 grams of radix scrophulariae, 5 grams of the root of large-flowered skullcap, 8 grams of the root of straight ladybell, 5 grams of the root bark of Chinese wolf-berry, are brewed into decoction plus 15 grams of lotus root juice take after mixing.
A kind of using method of auxiliary treatment dog cat diabetes medicament of the present invention, the using method is:Above medicinal material (is removed Lotus root juice) decoction is brewed into plus 15 grams of lotus root juice takes after mixing, one time a day gavages, can long-term taking.
Analyze with reference to pharmacological and the application principle of the present invention is explained in detail.
The present invention treats method of the initial stage using the combination of Chinese tradiational and Western medicine in order to ensure curative effect, to make up alone " ten tastes drop The shortcoming that liquid glucose " can not take effect in a short time;For the new approaches that medical worker from now on provides treatment;It is theoretical from traditional doctor trained in Western medicine Show;Doctor trained in Western medicine viewpoint:Diabetes are the metabolic diseases being characterized with hyperglycaemia, and chronic hyperglycemia often results in various internal organs, especially It is eye, kidney, neural and cardiovascular long-term damage, be one group by defect of insulin secretion and (or) infringement, insufficiency and Exhaustion.But consider from traditional Chinese medical science viewpoint:Diabetes can belong in diabetes category, and diabetes clinical manifestation is many drinks, many foods, many Urine, body are become thin, or urinate pleasantly sweet, and the traditional Chinese medical science thinks that its interpretation of the cause, onset and process of an illness mainly examines tax deficiency, YIN fluid deficiency, scorching inclined victory.Traditional Chinese medicine Treatment diabetes with supplementing qi and nourishing yin and control kidney method as the main rules for the treatment of more.The present invention has no side effect per auxiliary, can long-term taking.This Bright formula, process is simple, it is with low cost, the blood sugar for suffering from diabetes dog cat can be substantially reduced after taking a period of time.
The application effect of the present invention is explained in detail with reference to specific embodiment.
Embodiment:
The old bitch at one about 11 years old age, with drowsiness, pain over renal region, drinks many food diuresis but build more in September, 2014 The symptom such as lose weight of becoming thin is gone to a doctor in Rongchang County of Southwestern University school district pets hospital, and menses sugar instrument monitoring and routine blood test monitor it Afterwards, it is diagnosed as:Diabetes.At that time hospital took insulin injection to control blood sugar, insulin injection after two hours blood sugar it is obvious Reduce, doctor's suggestion is suffered from dog and need to daily inject quantitative insulin to control blood sugar, and be possible to insulin occur later to resist Property need to improve insulin dosage.Afterwards really as described in doctor, insulin dosage is gradually increased and just make glycemic control in normal model Enclose interior and pain over renal region symptom not improving.Adopt the technical scheme, insulin dosage simultaneously in December, 2014 later Slowly successively decrease, insulin is stopped using in November, 2015, continue to adopt the patent treatment, later Jing the method treatment phase Between glycemic control in normal range (NR), pain over renal region slightly mitigates, and drinks diuresis symptom mitigation more, and fur is gradually bright, and build is returned Reform often, this treatment method also stops after in May, 2016.So far insulin stops injection more than 1 year, the technology treatment method Stop eight months as long as, blood sugar is constantly in normal level.During being treated using the treatment technology, hospital also sees and treat patients successively The diabetes of several old dog cats, are treated using above method, and the case of the Jing patent of invention auxiliary treatments reaches Preferably adjuvant treatment effect is so as to reaching good therapeutic effect.
Presently preferred embodiments of the present invention is the foregoing is only, not to limit the present invention, all essences in the present invention Any modification, equivalent and improvement made within god and principle etc., should be included within the scope of the present invention.

Claims (3)

1. a kind of auxiliary treatment dog cat diabetes medicament, it is characterised in that the auxiliary treatment dog cat diabetes medicament is according to weight Amount percentage is by the coptis 5.68%, pollen 17.05%, the dried rhizome of rehmannia 17.05%, the tuber of dwarf lilyturf 5.68%, the wind-weed 5.68%, radix scrophulariae 11.36%th, the root of large-flowered skullcap 5.68%, the root of straight ladybell 9.09%, the root bark of Chinese wolf-berry 5.68% and lotus root juice 17.05% are constituted.
2. a kind of preparation method of auxiliary treatment dog cat diabetes medicament as claimed in claim 1, it is characterised in that the auxiliary The preparation method for the treatment of dog cat diabetes medicament is comprised the following steps:
Step one, first the coptis, radix rehmanniae recen, the tuber of dwarf lilyturf, the wind-weed, radix scrophulariae, the root of large-flowered skullcap, the root of straight ladybell, the root bark of Chinese wolf-berry, clean after, and pollen roasts Do, dry or dry and be standby;
Step 2, the component per auxiliary carries out weighing 5 grams of the coptis, 15 grams of pollen, 15 grams of the dried rhizome of rehmannia, 5 grams of the tuber of dwarf lilyturf, the wind-weed by weight 5 grams, 10 grams of radix scrophulariae, 5 grams of the root of large-flowered skullcap, 8 grams of the root of straight ladybell, 5 grams of the root bark of Chinese wolf-berry, decoction is brewed into after mixing plus 15 grams of lotus root juice takes.
3. the preparation method of auxiliary treatment dog cat diabetes medicament as claimed in claim 2, it is characterised in that the auxiliary is controlled Treat dog cat diabetes medicament using method be:By the coptis, pollen, the dried rhizome of rehmannia, the tuber of dwarf lilyturf, the wind-weed, radix scrophulariae, the root of large-flowered skullcap, the root of straight ladybell, the root bark of Chinese wolf-berry Decoction is brewed into after mixing, plus lotus root juice takes, one time a day gavages.
CN201710132278.8A 2017-03-07 2017-03-07 Medicament for treating diabetes mellitus in dogs and cats in adjuvant way and preparation method thereof Pending CN106620233A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112826890A (en) * 2021-03-25 2021-05-25 潘淑艳 Medicine for treating diabetes

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112826890A (en) * 2021-03-25 2021-05-25 潘淑艳 Medicine for treating diabetes

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Application publication date: 20170510