CN106620166A - Externally-used antidote for detoxicating bee venom, and preparation method of antidote - Google Patents
Externally-used antidote for detoxicating bee venom, and preparation method of antidote Download PDFInfo
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Abstract
In order to making up the gap in the prior art, the invention provides an externally-used antidote for detoxicating bee venom. The externally-used antidote is prepared from the following components in parts by weight: 5-1050 parts of a first herbal medicine component, 20-1600 parts of a second herbal medicine component and 50-500 parts of acetic acid, wherein the first herbal medicine component is prepared from one or more of pokeberry root, Chinese honeylocust spine, rhizoma paridis and radix oenotherae odoratae; the second herbal medicine component is prepared from one or more of leaf of winter jasmine, herba moslae chinensis, herba taraxaci, herba violae and herba lobeliae chinensis. A preparation method of the externally-used antidote for detoxicating the bee venom comprises the steps of S1, cleaning the herbal medicines, and preparing an acetic acid solution, wherein the acetic acid content of the acetic acid solution is more than or equal to 2.0g/100ml; S2, enabling the cleaned herbal medicines to be submerged into the acetic acid solution for soaking; S3, carrying out solid-liquid separation after the soaking is finished, wherein an obtained liquid phase product is the externally-used antidote for detoxicating the bee venom. After the externally-used antidote for detoxicating the bee venom is used, the spread of the bee venom can be obviously relieved within 10 seconds, and the swelling can be diminished within 2h.
Description
Technical field
The invention belongs to externally applied drug preparing technical field, and in particular to a kind of bee venom external application antidote and preparation method thereof.
Background technology
Honeybee is insect common in a kind of life, that includes honeybee, hornet, Mount Huang hair honeybee, yellow bow-tie honeybee, Chinese honeybee,
Red pin bees with slender waist, suede mutillid, Taiwan pompilid, yellow waist tiger head honeybee, black abdomen tiger head honeybee, yellow pin tiger head honeybee, black tail wasp, yellow long pin
Honeybee, becomes the different wasp in side, the thin honeybee of blattaria etc..And almost all of honeybee can all cause the different degrees of poisoning of human body after human body is bitten
Reaction, light bee venom can cause the malaise symptoms such as human body pain, redness, but can be completed certainly by human body itself over time
So removing toxic substances.But there are many honeybees, such as wasp, biting can produce violent acute poisoning reaction after human body, such as can not locate in time
Reason, gently then makes human body fall old complaint or cause deformity, heavy then make one shock even death.Every year the country or state nearly all occurs
Outward because being bitten the casualties event for causing by wasp.
Then, for honeybee sting, currently still without a specific drug, common processing method among the people is to use soap
Or caustic dip, the method can it is certain cross in degree to alleviate honeybee and bite the uncomfortable or poisoning that causes manifest, but for
The wasp of severe toxicity is bitten almost without effect.Additionally, honeybee sting often occurs in field or woodland, soap is not that people go out
Standing article, alkali lye is not only standing and not portable, not easy to maintain.Therefore, when there is acute bee venom poisoning, generally
Need to hospital to be rescued, but due to lacking wasp aptoxin specific drug, and give to examine and be necessarily required to the regular hour,
Irreversible damage or even dead generally also can be caused to human body.
The content of the invention
The present invention lacks bee venom specific drug, the especially vacancy of wasp aptoxin specific drug to make up prior art, there is provided
One kind can be with emergency processing honeybee sting, the specific drug that especially wasp bites.The medicine is bee venom external application antidote, by weight
Number meter, including：First herbal medicine component 5-1050 parts and acetic acid 50-500 parts.Wherein, the first herbal medicine component includes：Phytolacca acinosa,
One or more in spina gleditsiae, Paris polyphylla, cordate telosma.
Further, the first herbal medicine component includes Phytolacca acinosa 150-300 parts and Paris polyphylla 5-50 parts.
Further, the first herbal medicine component include Phytolacca acinosa 150-300 parts, Paris polyphylla 5-50 parts, spina gleditsiae 30-500 parts,
Cordate telosma 10-150 parts.
Further, count by weight, the bee venom external application antidote includes second herbal medicine component 20-1600 parts.Institute
Stating the second herbal medicine component includes：One or more in winter jasmine leaf, wild catmint, dandelion, Chinese violet, Chinese lobelia.
Further, the second herbal medicine component includes：Winter jasmine leaf 30-500 parts, wild catmint 20-200 parts.
Further, the second herbal medicine component includes：Winter jasmine leaf 30-500 parts, wild catmint 20-200 parts, dandelion
20-200 parts, Chinese violet 50-300 parts.
Further, above-mentioned bee venom external application antidote is prepared by the following method：
S1. herbal medicine is cleaned, and configures the acetum of acetic acid content >=2.0g/100ml.
S2. clean herbal medicine is completely immersed in aqueous acetic acid and is soaked.
S3. separation of solid and liquid is carried out after the completion of soaking, gained liquid product is the bee venom external application antidote.
Further, described in step S1 in acetum, the acetum of acetic acid content 2.0-6.0g/100ml is adopted
Vinegar allotment is obtained.The acetum of more than acetic acid content 6.0g/100ml is by the way that vinegar to be placed in 10-60 DEG C of subnormal ambient
In be concentrated to give.
Further, the herbal medicine cleaned described in step S2, for dry product is crushed to after 20-50 mesh aqueous acetic acid is immersed
In.For fresh goods, it is cut to after the section of 1-10cm and immerses in aqueous acetic acid.
Further, the method for separation of solid and liquid described in step S3 is：Filtered using the screen cloth of 60-100 mesh.
The present invention is at least to have one of the following advantages：
1., there is honeybee sting after affected part external application in present invention gained bee venom external application antidote, can obviously relieve within 10 seconds
Bee venom spreads phenomenon, can sterilization, detumescence typically within 2 hours.
2. the present invention gained bee venom external application antidote, obvious scar is hardly produced after use, will not leave behind because
Bubble hole caused by red and swollen, the damage to human body is less.
3. bee venom external application antidote of the present invention, preparation process is simple, and the gained liquid phase antidote shelf-life is typically at 12 months
More than, and it is easy to carry, it is easy to use, can be used as the conventional deposit medicine of the personnel such as field trip, bee raising.
Specific embodiment
In order that the objects, technical solutions and advantages of the present invention become more apparent, below to of the invention further detailed
Explanation.It should be appreciated that specific embodiment described herein is not intended to limit the present invention only to explain the present invention.
Embodiment 1
A kind of bee venom external application antidote, including Phytolacca acinosa 150g, acetic acid 50g.Its preparation method is：It is stand-by after Phytolacca acinosa is cleaned, will
Acetic acid is configured to after the aqueous solution of 2.0g/100ml, by clean Phytolacca acinosa immersion aqueous acetic acid.Immersion completes leaching after 15 days
Bubble operation, takes liquid phase component therein after separation of solid and liquid, obtain the bee venom external application antidote.
Embodiment 2
A kind of bee venom external application antidote, including Phytolacca acinosa 200g, Paris polyphylla 50g, acetic acid 500g.Its preparation method is：Spina gleditsiae is washed
It is stand-by after net, acetic acid is configured to after the aqueous solution of 6.0g/100ml, by clean Phytolacca acinosa, Paris polyphylla immersion aqueous acetic acid.
Immersion completes dip operation after 6 days, and liquid phase component therein is taken after separation of solid and liquid, obtains the bee venom external application antidote.
Embodiment 3
A kind of bee venom external application antidote, including Phytolacca acinosa 300g, Paris polyphylla 5g, spina gleditsiae 500g, acetic acid 450g.Its preparation method is：
It is stand-by after winter jasmine leaf is cleaned, acetic acid is configured to after the aqueous solution of 3.5g/100ml, by clean Phytolacca acinosa, Paris polyphylla, Chinese honey locust
Thorn is smashed to pieces in immersion aqueous acetic acid.Immersion completes dip operation after 10 days, and liquid phase component therein is taken after separation of solid and liquid, obtains
The bee venom external application antidote.
Embodiment 4
A kind of bee venom external application antidote, including Phytolacca acinosa 230g, Paris polyphylla 30g, spina gleditsiae 30g, cordate telosma 150g, acetic acid 150g.Its
Preparation method is：It is stand-by after Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma are cleaned, acetic acid is configured into the aqueous solution of 4.5g/100ml
Afterwards, by clean Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma immersion aqueous acetic acid.Immersion completes dip operation, solid-liquid after 7 days
Liquid phase component therein is taken after separation, the bee venom external application antidote is obtained.
Applicant has found that acetic acid can effectively suppress long range diffusion of the wasp aptoxin in human body, have through research
The effect of certain neutralization bee venom, but acetic acid is used alone can not fundamentally treat wasp aptoxin, and acetic acid to honey
The bee venom therapy effect on driving birds is not good of honeybee class.Directly it is applied directly to honeybee sting affected part, when coming into force of medicine using aqueous acetic acid
Between generally more than 30 minutes, treatment time short then 4-5 hours, long then a couple of days, or even can not subside a swelling.The entry-into-force time is bee venom
Diffusion be substantially suppressed the time for needing, the treatment time is the time that detumescence needs.
, through substantial amounts of research and trial, finding can after Phytolacca acinosa, spina gleditsiae, Paris polyphylla, cordate telosma and acetic acid compounding for applicant
With substantially play a part of suppress bee venom diffusion, neutralize bee venom and detumescence of drawing out pus by applying a plaster to the affected part, its entry-into-force time in 3-10 minutes, during treatment
Between be less than 4 hours, in its Chinese herbal medicine component contain Phytolacca acinosa when, compound product drug effect it is optimal.Then, applicant attempts only adopting
After being compounded with other medicinal materials with Phytolacca acinosa and Phytolacca acinosa, its juice external application is squeezed, its entry-into-force time is often longer than 1 hour, and needs 6 are little
When more than could subside a swelling.The reason for producing the phenomenon may is that：Synergy is defined between Phytolacca acinosa and acetic acid, both are common
The infiltration and absorption of Phytolacca acinosa are promoted while bee venom diffusion, neutralization bee venom is suppressed using rear acetic acid, Phytolacca acinosa has for bee venom
There is the stronger effect of drawing out pus by applying a plaster to the affected part, can reversely suppress the diffusion of bee venom, bee venom is concentrated near wound, so as to improve acetic acid
Neutralization efficiency.
Then at acetic acid compounding after one or more in Phytolacca acinosa compounding spina gleditsiae, Paris polyphylla, cordate telosma, can further reduce
Entry-into-force time and treatment time, under optimum formula, the entry-into-force time is about 3 minutes, and treatment time is about 2 hours.Its possible original
Because being：Spina gleditsiae, Paris polyphylla, cordate telosma further enhance the effect of drawing out pus by applying a plaster to the affected part of Phytolacca acinosa, and with the effect of certain neutralization bee venom
Really.Meanwhile, it is found by the applicant that after one or more compounding in Phytolacca acinosa and spina gleditsiae, Paris polyphylla, cordate telosma, can also be obviously reduced
Bubble pit-size caused by being corroded due to bee venom.
Embodiment 5
A kind of bee venom external application antidote, including Phytolacca acinosa 230g, Paris polyphylla 40g, spina gleditsiae 100g, cordate telosma 10g, winter jasmine 500g,
Acetic acid 100g.Its preparation method is：It is stand-by after Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine are cleaned, acetic acid is configured to
After the aqueous solution of 4.0g/100ml, by clean Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine immersion aqueous acetic acid.
Immersion completes dip operation after 7 days, and liquid phase component therein is taken after separation of solid and liquid, obtains the bee venom external application antidote.
Embodiment 6
A kind of bee venom external application antidote, including Phytolacca acinosa 160g, Paris polyphylla 40g, spina gleditsiae 100g, cordate telosma 30g, winter jasmine 30g, open country
Schizonepeta 200g, acetic acid 150g.Its preparation method is：After Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine, wild catmint are cleaned
It is stand-by, acetic acid is configured to after the aqueous solution of 4.5g/100ml, by clean Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine,
In wild catmint immersion aqueous acetic acid.Immersion completes dip operation after 7 days, and liquid phase component therein is taken after separation of solid and liquid, obtains
The bee venom external application antidote.
Embodiment 7
A kind of bee venom external application antidote, including Phytolacca acinosa 160g, Paris polyphylla 40g, spina gleditsiae 100g, cordate telosma 30g, winter jasmine 30g, open country
Schizonepeta 20g, dandelion 200g, acetic acid 250g.Its preparation method is：By Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine, open country
Schizonepeta, dandelion are stand-by after cleaning, and acetic acid is configured to after the aqueous solution of 4.5g/100ml, by clean Phytolacca acinosa, Paris polyphylla, Chinese honey locust
In thorn, cordate telosma, winter jasmine, wild catmint, dandelion immersion aqueous acetic acid.Immersion completes dip operation, separation of solid and liquid after 7 days
After take liquid phase component therein, obtain the bee venom external application antidote.
Embodiment 8
A kind of bee venom external application antidote, including Phytolacca acinosa 160g, Paris polyphylla 40g, spina gleditsiae 100g, cordate telosma 30g, winter jasmine 30g, open country
Schizonepeta 50g, dandelion 20g, Chinese violet 300g, acetic acid 350g.Its preparation method is：By Phytolacca acinosa, Paris polyphylla, spina gleditsiae, yesterday
Perfume, winter jasmine, wild catmint, dandelion, Chinese violet are stand-by after cleaning, and acetic acid is configured to after the aqueous solution of 4.5g/100ml,
By clean Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine, wild catmint, dandelion, Chinese violet immersion aqueous acetic acid
In.Immersion completes dip operation after 7 days, and liquid phase component therein is taken after separation of solid and liquid, obtains the bee venom external application antidote.
Embodiment 9
A kind of bee venom external application antidote, including Phytolacca acinosa 280g, Paris polyphylla 35g, spina gleditsiae 120g, cordate telosma 80g, winter jasmine 400g,
Wild catmint 120g, dandelion 120g, Chinese violet 50g, acetic acid 350g.Its preparation method is：By Phytolacca acinosa, Paris polyphylla, spina gleditsiae, night
Come stand-by after fragrant, winter jasmine, wild catmint, dandelion, Chinese violet are cleaned, acetic acid is configured into the aqueous solution of 4.5g/100ml
Afterwards, it is clean Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine, wild catmint, dandelion, Chinese violet immersion acetic acid is water-soluble
In liquid.Immersion completes dip operation after 7 days, and liquid phase component therein is taken after separation of solid and liquid, obtains the bee venom external application antidote.
Embodiment 10
A kind of bee venom external application antidote, including Phytolacca acinosa 260g, Paris polyphylla 25g, spina gleditsiae 350g, cordate telosma 110g, winter jasmine 350g,
Wild catmint 150g, dandelion 120g, Chinese violet 130g, acetic acid 350g.Its preparation method is：By Phytolacca acinosa, Paris polyphylla, spina gleditsiae,
Cordate telosma, winter jasmine, wild catmint, dandelion, Chinese violet are stand-by after cleaning, and acetic acid is configured into the aqueous solution of 4.5g/100ml
Afterwards, it is clean Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine, wild catmint, dandelion, Chinese violet immersion acetic acid is water-soluble
In liquid.Immersion completes dip operation after 7 days, and liquid phase component therein is taken after separation of solid and liquid, obtains the bee venom external application antidote.
Applicant has found through research, on the basis of Phytolacca acinosa, spina gleditsiae, Paris polyphylla, cordate telosma, aids in winter jasmine, open country
One or more in schizonepeta, dandelion, Chinese violet, Chinese lobelia, can further improve the drug effect of medicine.Optimal formula
Under, within the entry-into-force time of antidote can be allowd to foreshorten to 10 seconds, draw out pus by applying a plaster to the affected part, within swelling time foreshortens to 2 hours.And
And there is alleviation and therapeutic action for most of honeybee sting, especially wasp is bitten with specific treatment effect.
Additionally, bubble hole caused by corroding for bee venom, because the entry-into-force time of the medicine is very short, therefore can substantially suppress honeybee
Erosion of the poison to human body.Under optimum formula, almost do not steep hole and formed, only exist the wound produced due to honeybee sting, wound
The vestige that bee venom corrodes almost is not seen after stammerer.
Embodiment 11
A kind of bee venom external application antidote, including Phytolacca acinosa 260g, Paris polyphylla 25g, spina gleditsiae 350g, cordate telosma 110g, winter jasmine 350g,
Wild catmint 150g, dandelion 120g, Chinese violet 130g, acetic acid 350g.Its preparation method is：
S1. after Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine, wild catmint, dandelion, Chinese violet being cleaned, will wherein
Dry product be crushed to 40 mesh, and the section that fresh goods therein is cut into 3cm is stand-by.Acetic acid is configured into the water-soluble of 4.5g/100ml
Liquid.
S2. by clean Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine, wild catmint, dandelion, Chinese violet immersion
In aqueous acetic acid.
S3. dip operation is completed after soaking 7 days, after being filtered using the screen cloth of 80 mesh, filtrate portion is removed, institute is obtained
State bee venom external application antidote.
Embodiment 12
A kind of bee venom external application antidote, including Phytolacca acinosa 260g, Paris polyphylla 25g, spina gleditsiae 350g, cordate telosma 110g, winter jasmine 350g,
Wild catmint 150g, dandelion 120g, Chinese violet 130g, acetic acid 350g.Its preparation method is：
S1. after Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine, wild catmint, dandelion, Chinese violet being cleaned, will wherein
Dry product be crushed to 40 mesh, and the section that fresh goods therein is cut into 3cm is stand-by.By the coloured food that acetic acid content is 4.5g/100ml
Vinegar is diluted to stand-by after 3.0g/100ml.
S2. by clean Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine, wild catmint, dandelion, Chinese violet immersion
In coloured vinegar.
S3. dip operation is completed after soaking 7 days, after being filtered using the screen cloth of 80 mesh, filtrate portion is removed, institute is obtained
State bee venom external application antidote.
After comparative example 11 and 12, it has been found that in the case of acetic acid content identical, being adjusted using vinegar or vinegar
With the aqueous solution soaking medicinal material for obtaining, the drug effect of gained filtrate is significantly stronger than using glacial acetic acid allotment solution immersion medicinal material gained filter
The drug effect of liquid.The reason for its is possible be：Vinegar is typically obtained using grain fermentation, in vinegar in addition to containing acetic acid, is also contained
There is substantial amounts of nutriment, these nutriments promote infiltration rate and uptake of the human body to active ingredient in liquid, from
And improve the drug effect of medicine.
Embodiment 13
A kind of bee venom external application antidote, including Phytolacca acinosa 260g, Paris polyphylla 25g, spina gleditsiae 350g, cordate telosma 110g, winter jasmine 350g,
Wild catmint 150g, dandelion 120g, Chinese violet 130g, acetic acid 350g.Its preparation method is：
S1. after Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine, wild catmint, dandelion, Chinese violet being cleaned, will wherein
Dry product be crushed to 40 mesh, and the section that fresh goods therein is cut into 3cm is stand-by.By the colourless food that acetic acid content is 4.5g/100ml
Vinegar is diluted to stand-by after 3.0g/100ml.
S2. by clean Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine, wild catmint, dandelion, Chinese violet immersion
In colourless vinegar.
S3. dip operation is completed after soaking 7 days, after being filtered using the screen cloth of 80 mesh, filtrate portion is removed, institute is obtained
State bee venom external application antidote.
Comparative example 12 and 13, it has been found that being better than colourless vinegar using the effect of coloured vinegar.Its possible original
Because being that colourless vinegar in decolorization, deviate from a large number by the nutriment for including, and causes it approximate with glacial acetic acid composition,
Lack the nutriment for promoting absorption of human body liquid active ingredient.
Embodiment 14
A kind of bee venom external application antidote, including Phytolacca acinosa 260g, Paris polyphylla 25g, spina gleditsiae 350g, cordate telosma 110g, winter jasmine 350g,
Wild catmint 150g, dandelion 120g, Chinese violet 130g, acetic acid 350g.Its preparation method is：
S1. after Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine, wild catmint, dandelion, Chinese violet being cleaned, will wherein
Dry product be crushed to 50 mesh, and the section that fresh goods therein is cut into 10cm is stand-by.It is the coloured of 4.5g/100ml by acetic acid content
Vinegar is diluted to stand-by after 3.0g/100ml.
S2. by clean Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine, wild catmint, dandelion, Chinese violet immersion
In coloured vinegar.
S3. dip operation is completed after soaking 7 days, after being filtered using the screen cloth of 100 mesh, filtrate portion is removed, institute is obtained
State bee venom external application antidote.
Embodiment 15
A kind of bee venom external application antidote, including Phytolacca acinosa 260g, Paris polyphylla 25g, spina gleditsiae 350g, cordate telosma 110g, winter jasmine 350g,
Wild catmint 150g, dandelion 120g, Chinese violet 130g, acetic acid 350g.Its preparation method is：
S1. after Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine, wild catmint, dandelion, Chinese violet being cleaned, will wherein
Dry product be crushed to 20 mesh, and the section that fresh goods therein is cut into 1cm is stand-by.By the coloured food that acetic acid content is 4.5g/100ml
Vinegar is diluted to stand-by after 3.0g/100ml.
S2. by clean Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine, wild catmint, dandelion, Chinese violet immersion
In colourless vinegar.
S3. dip operation is completed after soaking 7 days, after being filtered using the screen cloth of 60 mesh, filtrate portion is removed, institute is obtained
State bee venom external application antidote.
Applicant has found through research, although after dry product medicinal material is crushed and cut off fresh goods medicinal material, its extraction time can
With relative shortening, although more broken medicinal material, the soak time of needs is general also shorter, but the behaviour needed in its subsequent filter
Make difficulty bigger.When needing to be filtered with screen clothes more than 100 mesh, the drug effect of gained medicinal material occurs a certain degree of
Decline, be the reason for its is possible：Too small mesh size can stay in the part active ingredient in liquid in filter residue, cause most
There is certain decline for crossing degree in the drug effect of whole filtrate.Additionally, fresh goods is cut excessively tiny, what it was lost in during segment
Active ingredient is excessive, so as to the active constituent content in filtrate can be caused to decline, so as to reduce drug effect.
Embodiment 16
A kind of bee venom external application antidote, including Phytolacca acinosa 260g, Paris polyphylla 25g, spina gleditsiae 350g, cordate telosma 110g, winter jasmine 350g,
Wild catmint 150g, dandelion 120g, Chinese violet 130g, acetic acid 350g.Its preparation method is：
S1. after Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine, wild catmint, dandelion, Chinese violet being cleaned, will wherein
Dry product be crushed to 40 mesh, and the section that fresh goods therein is cut into 3cm is stand-by.Acetic acid is configured into the water-soluble of 2.0g/100ml
Liquid.
S2. by clean Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine, wild catmint, dandelion, Chinese violet immersion
In aqueous acetic acid.
S3. dip operation is completed after soaking 7 days, after being filtered using the screen cloth of 80 mesh, filtrate portion is removed, institute is obtained
State bee venom external application antidote.
Embodiment 17
A kind of bee venom external application antidote, including Phytolacca acinosa 260g, Paris polyphylla 25g, spina gleditsiae 350g, cordate telosma 110g, winter jasmine 350g,
Wild catmint 150g, dandelion 120g, Chinese violet 130g, acetic acid 350g.Its preparation method is：
S1. after Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine, wild catmint, dandelion, Chinese violet being cleaned, will wherein
Dry product be crushed to 40 mesh, and the section that fresh goods therein is cut into 3cm is stand-by.Acetic acid is configured into the water-soluble of 10.0g/100ml
Liquid.
S2. by clean Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine, wild catmint, dandelion, Chinese violet immersion
In aqueous acetic acid.
S3. dip operation is completed after soaking 7 days, after being filtered using the screen cloth of 80 mesh, filtrate portion is removed, institute is obtained
State bee venom external application antidote.
Applicant has found through research, in the present invention, optimum medicine efficacy can be formed between acetum and herbal medicine and is cooperateed with
The scope of effect is the acetum of acetic acid content 2.0-10.0g/100ml.The reason for its is possible be：The too low nothing of acetic acid content
Method forms sufficient concentrations of filtrate, causes drug effect not good.Acetic acid content is too high to be suppressed in leaching process to medicinal material active ingredient
Extracting effect, cause active constituent content in filtrate relatively low, and acetic acid content is too high is likely to inhibit in herbal medicine effectively
The property of medicine of composition, causes its partial failure.
Embodiment 18
A kind of bee venom external application antidote, including Phytolacca acinosa 260g, Paris polyphylla 25g, spina gleditsiae 350g, cordate telosma 110g, winter jasmine 350g,
Wild catmint 150g, dandelion 120g, Chinese violet 130g, acetic acid 350g.Its preparation method is：
S1. after Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine, wild catmint, dandelion, Chinese violet being cleaned, will wherein
Dry product be crushed to 40 mesh, and the section that fresh goods therein is cut into 3cm is stand-by.Vinegar is placed in 40 DEG C of subnormal ambient and is concentrated
Obtain the vinegar solution of 10.0g/100ml.
S2. by clean Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine, wild catmint, dandelion, Chinese violet immersion
In aqueous acetic acid.
S3. dip operation is completed after soaking 7 days, after being filtered using the screen cloth of 80 mesh, filtrate portion is removed, institute is obtained
State bee venom external application antidote.
Embodiment 19
A kind of bee venom external application antidote, including Phytolacca acinosa 260g, Paris polyphylla 25g, spina gleditsiae 350g, cordate telosma 110g, winter jasmine 350g,
Wild catmint 150g, dandelion 120g, Chinese violet 130g, acetic acid 350g.Its preparation method is：
S1. after Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine, wild catmint, dandelion, Chinese violet being cleaned, will wherein
Dry product be crushed to 40 mesh, and the section that fresh goods therein is cut into 3cm is stand-by.Vinegar is placed in 60 DEG C of subnormal ambient and is concentrated
Obtain the vinegar solution of 6.0g/100ml.
S2. by clean Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine, wild catmint, dandelion, Chinese violet immersion
In aqueous acetic acid.
S3. dip operation is completed after soaking 7 days, after being filtered using the screen cloth of 80 mesh, filtrate portion is removed, institute is obtained
State bee venom external application antidote.
Embodiment 20
A kind of bee venom external application antidote, including Phytolacca acinosa 260g, Paris polyphylla 25g, spina gleditsiae 350g, cordate telosma 110g, winter jasmine 350g,
Wild catmint 150g, dandelion 120g, Chinese violet 130g, acetic acid 350g.Its preparation method is：
S1. after Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine, wild catmint, dandelion, Chinese violet being cleaned, will wherein
Dry product be crushed to 40 mesh, and the section that fresh goods therein is cut into 3cm is stand-by.Vinegar is placed in 10 DEG C of subnormal ambient and is concentrated
Obtain the vinegar solution of 8.0g/100ml.
S2. by clean Phytolacca acinosa, Paris polyphylla, spina gleditsiae, cordate telosma, winter jasmine, wild catmint, dandelion, Chinese violet immersion
In aqueous acetic acid.
S3. dip operation is completed after soaking 7 days, after being filtered using the screen cloth of 80 mesh, filtrate portion is removed, institute is obtained
State bee venom external application antidote.
Applicant has found through research, because the acetate concentration in common vinegar is typically not greater than 5.0g/100ml, therefore,
For acetum of the acetate concentration more than 5.0g/100ml, need to be used after traditional vinegar is concentrated.However, such as utilizing more than
60 DEG C of temperature is evaporated concentration, and the entry-into-force time of final products occurs a certain degree of prolongation, the reason for its is possible
In high temperature changes the composition of some nutriments in vinegar so as to inactivate, and causes the promotion assimilation effect of vinegar and reduces, and prolongs
The entry-into-force time of final products is grown.By additional negative pressure, it is possible to achieve the rapid evaporation concentration below 60 DEG C, that is, protect
Nutriment in vinegar, in turn ensure that production efficiency.
The present invention at least has one of the following advantages：
1., there is honeybee sting after affected part external application in present invention gained bee venom external application antidote, can obviously relieve within 10 seconds
Bee venom spreads phenomenon, can sterilization, detumescence typically within 2 hours.
2. the present invention gained bee venom external application antidote, obvious scar is hardly produced after use, will not leave behind because
Bubble hole caused by red and swollen, the damage to human body is less.
3. bee venom external application antidote of the present invention, preparation process is simple, and the gained liquid phase antidote shelf-life is typically at 12 months
More than, and it is easy to carry, it is easy to use, can be used as the conventional deposit medicine of the personnel such as field trip, bee raising.
It should be noted that and understand, in the case of without departing from the spirit and scope required by the claims in the present invention, energy
Enough present invention to foregoing detailed description make various modifications and improvements.It is therefore desirable to the scope of the technical scheme of protection is not received
The restriction of given any specific exemplary teachings.
Claims (10)
1. bee venom external application antidote, it is characterised in that count by weight, including：First herbal medicine component 5-1050 parts and acetic acid
50-500 parts；Wherein, the first herbal medicine component includes：One or more in Phytolacca acinosa, spina gleditsiae, Paris polyphylla, cordate telosma.
2. bee venom external application antidote according to claim 1, it is characterised in that the first herbal medicine component includes Phytolacca acinosa 150-
300 parts and Paris polyphylla 5-50 parts.
3. bee venom external application antidote according to claim 1, it is characterised in that the first herbal medicine component includes Phytolacca acinosa 150-
300 parts, Paris polyphylla 5-50 parts, spina gleditsiae 30-500 parts, cordate telosma 10-150 parts.
4. bee venom external application antidote according to claim 1, it is characterised in that count by weight, the bee venom external application solution
Toxic agent includes second herbal medicine component 20-1600 parts；The second herbal medicine component includes：Winter jasmine leaf, wild catmint, dandelion, purple
One or more in flower Chinese violet, Chinese lobelia.
5. bee venom external application antidote according to claim 4, it is characterised in that the second herbal medicine component includes：Winter jasmine
Leaf 30-500 parts, wild catmint 20-200 parts.
6. bee venom external application antidote according to claim 4, it is characterised in that the second herbal medicine component includes：Winter jasmine
Leaf 30-500 parts, wild catmint 20-200 parts, dandelion 20-200 parts, Chinese violet 50-300 parts.
7. the bee venom external application antidote according to claim 1-6 any one, it is characterised in that the bee venom external application antidote
It is prepared by the following method：
S1. herbal medicine is cleaned, and configures the acetum of acetic acid content >=2.0g/100ml；
S2. clean herbal medicine is completely immersed in aqueous acetic acid and is soaked；
S3. separation of solid and liquid is carried out after the completion of soaking, gained liquid product is the bee venom external application antidote.
8. bee venom external application antidote according to claim 7, it is characterised in that described in step S1 in acetum, acetic acid
The acetum of content 2.0-6.0g/100ml is obtained using vinegar allotment；The acetum of more than acetic acid content 6.0g/100ml
It is concentrated to give in by the way that vinegar to be placed in 10-60 DEG C of subnormal ambient.
9. bee venom external application antidote according to claim 7, it is characterised in that the herbal medicine cleaned described in step S2, for dry
Product are crushed to after 20-50 mesh and immerse in aqueous acetic acid；For fresh goods, it is cut to after the section of 1-10cm and immerses in aqueous acetic acid.
10. bee venom external application antidote according to claim 7, it is characterised in that the method for separation of solid and liquid described in step S3 is：
Filtered using the screen cloth of 60-100 mesh.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113209196A (en) * | 2021-03-16 | 2021-08-06 | 宁夏医科大学 | Traditional Chinese medicine composition related to atherosclerotic plaque stability and application thereof |
| CN114886995A (en) * | 2022-05-07 | 2022-08-12 | 李广科 | Disinfecting and sterilizing composition |
-
2017
- 2017-01-19 CN CN201710039686.9A patent/CN106620166A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113209196A (en) * | 2021-03-16 | 2021-08-06 | 宁夏医科大学 | Traditional Chinese medicine composition related to atherosclerotic plaque stability and application thereof |
| CN114886995A (en) * | 2022-05-07 | 2022-08-12 | 李广科 | Disinfecting and sterilizing composition |
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