CN106619885A - Clinic enema for treating ulcerative colitis - Google Patents
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Abstract
The invention discloses clinic enema for treating ulcerative colitis. The clinic enema for treating ulcerative colitis is prepared from the following raw materials by decoction and concentration: 20-25 g of Cortex syzygii cumini, 15-25 g of Herba Adianti Flabellulati, 10-12 g of Herba Pteridis multifidae, 15-17 g of Herba Stellariae paniculigerae, 6-8 g of Radix Sophorae Flavescentis, 30-40 g of Radix Fici comatae, 6-12 g of Rhizoma Polygoni coriacei, 12-15 g of Rhizoma Corydalis, 10-12 g of Radix Paeoniae Alba, 7-9 g of Fructus pruni pubescentis and 4-6 g of Radix Glycyrrhizae. The clinic enema has the beneficial effects that (1) the clinic enema can directly act on an affected part, blood circulation of a colon part is improved by clearing heat and expelling damp, benefiting qi and checking blood, and promoting blood circulation to remove obstruction in the collateral, inflammation diminishing is promoted, repair of colonic ulcer is promoted, colonic inflammation is inhibited, and the treatment effect is good; (2) the clinic enema is short in course of treatment and good in curative effect, and does not have toxic or side effects; and (3) the clinic enema is simple and reasonable in preparation, wide in medicinal herbs resource and convenient to use.
Description
Technical field
The present invention relates to a kind of clinical enema, and in particular to a kind of clinical coloclysis for treating ulcerative colitiss
Liquid, belongs to field of medicaments.
Background technology
Ulcerative colitiss (UC) typically refer to the chronic inflammatory disease and exedens pathological changes of colorectal mucosa, and its pathological changes is generally from straight
Intestinal, colon start, and reversibility proximally develops, and are often distributed in diffusivity, occasionally in segmental, and sigmoid colon and descending colon are main
Pathological changes are broken-hearted, and severe patient can involve total colectomy, or even terminal ileum.If focus only involves rectum, we it be called exedens
Proctitis.UC is more common in the young and the middle aged of -40 years old 20 years old, is occasionally found in child and old age, with suffer from abdominal pain, diarrhoea, mucopurulent bloody stool and
Tenesmus are cardinal symptom.The easy recurrent exerbation of primary disease, protracted course of disease have a strong impact on the quality of life of patient, are defended by the world
Raw tissue is set to one of modern difficult treatment.
" having loose bowels ", " lower profit ", " intestinal is warded off " category in ulcerative colitiss (UC) category Chinese medicine.Morbidity it is many because being invaded by exogenous pathogen,
Internal organs are damp and hot, injury of small vessels, and gradually cause stagnation of liver-QI with deficiency of the spleen, qi depression to blood stasis, weakened body resistance large intestine to slide and rush down not admittedly.
Western medical treatment is only capable of receiving short term effect using antibiotic or sulfa drugss, and long-term effect is not good, and drug withdrawal is then suffered from diarrhoea
Stomachache is as before.
The content of the invention
To solve the deficiencies in the prior art, it is an object of the invention to provide a kind of for treating facing for ulcerative colitiss
Bed enema, which can directly act on affected part, with good therapeutic effect.
In order to realize above-mentioned target, the present invention is adopted the following technical scheme that：
A kind of clinical enema for treating ulcerative colitiss, it is characterised in that by following raw material Jing decoctings, concentration
Make：
Cortex syzygii cumini 20-25g, Herba Adianti Flabellulati 15-25g, Herba Pteridis multifidae 10-12g, Herba Stellariae paniculigerae 15-17g, Radix Sophorae Flavescentiss 6-8g, clump
Mao Ronggen 30-40g, Rhizoma Polygoni coriacei 6-12g, Rhizoma Corydalis 12-15g, Radix Paeoniae Alba 10-12g, Fructus pruni pubescentis 7-9g, Radix Glycyrrhizae 4-6g.
It is previously described for treating the clinical enema of ulcerative colitiss, it is characterised in that by following raw material Jing decoctings, dense
Contraction into：
Cortex syzygii cumini 22g, Herba Adianti Flabellulati 20g, Herba Pteridis multifidae 11g, Herba Stellariae paniculigerae 16g, Radix Sophorae Flavescentiss 7g, Radix Fici comatae 35g, companion Serpentiss
Lotus 8g, Rhizoma Corydalis 13g, Radix Paeoniae Alba 11g, Fructus pruni pubescentis 8g, Radix Glycyrrhizae 5g.
It is previously described for treating the clinical enema of ulcerative colitiss, it is characterised in that by following raw material Jing decoctings, dense
Contraction into：
Cortex syzygii cumini 21g, Herba Adianti Flabellulati 16g, Herba Pteridis multifidae 11g, Herba Stellariae paniculigerae 16g, Radix Sophorae Flavescentiss 6g, Radix Fici comatae 32g, companion Serpentiss
Lotus 7g, Rhizoma Corydalis 12g, Radix Paeoniae Alba 10g, Fructus pruni pubescentis 7g, Radix Glycyrrhizae 6g.
It is previously described for treating the clinical enema of ulcerative colitiss, it is characterised in that by following raw material Jing decoctings, dense
Contraction into：
Cortex syzygii cumini 22g, Herba Adianti Flabellulati 17g, Herba Pteridis multifidae 10g, Herba Stellariae paniculigerae 17g, Radix Sophorae Flavescentiss 8g, Radix Fici comatae 37g, companion Serpentiss
Lotus 10g, Rhizoma Corydalis 14g, Radix Paeoniae Alba 12g, Fructus pruni pubescentis 8g, Radix Glycyrrhizae 4g.
It is previously described for treating the clinical enema of ulcerative colitiss, it is characterised in that by following raw material Jing decoctings, dense
Contraction into：
Cortex syzygii cumini 23g, Herba Adianti Flabellulati 24g, Herba Pteridis multifidae 11g, Herba Stellariae paniculigerae 15g, Radix Sophorae Flavescentiss 7g, Radix Fici comatae 36g, companion Serpentiss
Lotus 9g, Rhizoma Corydalis 13g, Radix Paeoniae Alba 11g, Fructus pruni pubescentis 9g, Radix Glycyrrhizae 5g.
Fang Zhong, the pharmacological action of ingredients are as follows：
Cortex syzygii cumini：Heat-clearing and toxic substances removing；
Herba Adianti Flabellulati：Clearing away heat-damp and promoting diuresis, dissipating blood stasis for subsidence of swelling；
Herba Pteridis multifidae：Clearing away heat-damp and promoting diuresis, hemostasia and promoting granulation, removing toxic substances and promoting subsidence of swelling；
Herba Stellariae paniculigerae：Regulating QI to expel dampness, promoting blood circulation and hemostasis, removing food stagnancy removing toxic substances；
Radix Sophorae Flavescentiss：Heat clearing and damp drying, parasite killing diuresis；
Radix Fici comatae：Expelling wind and removing dampness, spleen invigorating；
Rhizoma Polygoni coriacei：Convergence, granulation promoting, heat-clearing and toxic substances removing；
Rhizoma Corydalis：Blood-activating and qi-promoting pain relieving；
The Radix Paeoniae Alba：Nourishing blood for regulating menstruation, smooth liver and relieve pain, astringing YIN to stop sweating；
Fructus pruni pubescentis：Spleen reinforcing, stopping leak are rushed down；
Radix Glycyrrhizae：Invigorating middle warmer and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough alleviate pain relieving.
Prescription is parsed：In side, Cortex syzygii cumini, Radix Sophorae Flavescentiss, Herba Stellariae paniculigerae heat-clearing and toxic substances removing, removing food stagnancy removing toxic substances, are monarch drug；Herba Pteridis multifidae,
Rhizoma Polygoni coriacei hemostasia and promoting granulation, regulating QI to expel dampness, are ministerial drug；Radix Fici comatae, Radix Glycyrrhizae, Fructus pruni pubescentis invigorating middle warmer and replenishing QI, stopping leak rush down, and are adjuvant drug；Rhizoma Corydalis
Rope, the Radix Paeoniae Alba, Herba Adianti Flabellulati reducing swelling and alleviating pain, to make medicine.Full side is made a general survey of, compatibility is rigorous, monarch, minister, help, make that clearly demarcated, hit exedens knot
The pathogenesis of enteritis, has fully demonstrated clearing heat, detoxicating, dispelling dampness, promoting blood circulation and hemostasis removing heat from blood, invigorating the spleen and benefiting QI the kidney invigorating, and promoting the circulation of QI to relieve pain antidiarrheal is controlled
Treat principle.
The invention has benefit that：
(1) this product can be done directly on affected part, by clearing heat and expelling damp, benefiting qi and checking blood, promoting blood circulation to remove obstruction in the collateral, make colon portion blood circulation
Improve, promote inflammatory resolution, promote the reparation of colonic ulcer, suppress colitis reaction, with good therapeutic effect.
(2) this product short treating period, good effect, have no toxic side effect.
(3) this product prepares simple, reasonable, and medicine source is wide, easy to use.
Specific embodiment
Make specific introduction to the present invention below in conjunction with specific embodiment.
First, prepare clinical enema
1st, get the raw materials ready
Medical material used includes：Cortex syzygii cumini, Herba Adianti Flabellulati, Herba Pteridis multifidae, Herba Stellariae paniculigerae, Radix Sophorae Flavescentiss, Radix Fici comatae, Rhizoma Polygoni coriacei,
Rhizoma Corydalis, the Radix Paeoniae Alba, Fructus pruni pubescentis, Radix Glycyrrhizae.
Each raw material is cleaned, it is then by the cleaning of each raw material, sterilizing, drying, crushing, stand-by.
2nd, mix
Jing clinical verifications in many years, following formula have good therapeutic effect, and the crowd being suitable for is also relatively broad：
Formula 1：Cortex syzygii cumini 22g, Herba Adianti Flabellulati 20g, Herba Pteridis multifidae 11g, Herba Stellariae paniculigerae 16g, Radix Sophorae Flavescentiss 7g, Radix Fici comatae
35g, Rhizoma Polygoni coriacei 8g, Rhizoma Corydalis 13g, Radix Paeoniae Alba 11g, Fructus pruni pubescentis 8g, Radix Glycyrrhizae 5g；
Formula 2：Cortex syzygii cumini 21g, Herba Adianti Flabellulati 16g, Herba Pteridis multifidae 11g, Herba Stellariae paniculigerae 16g, Radix Sophorae Flavescentiss 6g, Radix Fici comatae
32g, Rhizoma Polygoni coriacei 7g, Rhizoma Corydalis 12g, Radix Paeoniae Alba 10g, Fructus pruni pubescentis 7g, Radix Glycyrrhizae 6g；
Formula 3：Cortex syzygii cumini 22g, Herba Adianti Flabellulati 17g, Herba Pteridis multifidae 10g, Herba Stellariae paniculigerae 17g, Radix Sophorae Flavescentiss 8g, Radix Fici comatae
37g, Rhizoma Polygoni coriacei 10g, Rhizoma Corydalis 14g, Radix Paeoniae Alba 12g, Fructus pruni pubescentis 8g, Radix Glycyrrhizae 4g；
Formula 4：Cortex syzygii cumini 23g, Herba Adianti Flabellulati 24g, Herba Pteridis multifidae 11g, Herba Stellariae paniculigerae 15g, Radix Sophorae Flavescentiss 7g, Radix Fici comatae
36g, Rhizoma Polygoni coriacei 9g, Rhizoma Corydalis 13g, Radix Paeoniae Alba 11g, Fructus pruni pubescentis 9g, Radix Glycyrrhizae 5g.
It should be noted that those skilled in the art are according to the knowledge grasped, with reference to the concrete condition of patient, Ke Yi
Appropriate adjustment is done to the concrete consumption of ingredients in following ranges, it is specific as follows：
Cortex syzygii cumini 20-25g, Herba Adianti Flabellulati 15-25g, Herba Pteridis multifidae 10-12g, Herba Stellariae paniculigerae 15-17g, Radix Sophorae Flavescentiss 6-8g, clump
Mao Ronggen 30-40g, Rhizoma Polygoni coriacei 6-12g, Rhizoma Corydalis 12-15g, Radix Paeoniae Alba 10-12g, Fructus pruni pubescentis 7-9g, Radix Glycyrrhizae 4-6g.
In the present embodiment, the consumption that we are recorded according to formula 1, formula 2, formula 3 and formula 4, accurately weighs each original
Material, it is stand-by.
3rd, decocting and concentration
Take after each taste Chinese medicine by formula, each taste Chinese medicine is put in water and soaks 1h, then decocting takes liquid 150mL, heat water
Two take liquid about 300mL, and finally mixing is concentrated into 400ml, adapt to be advisable with temperature and human body temperature, retention enema.
2nd, case selection
Selected case is in May, 2013 in November, 2015 our hospital out-patient, 300 altogether, random by medical order
It is divided into treatment group and matched group, wherein：
Treatment group 150, male 76, female 74, -70 years old 17 years old age, average 46.8 ± 4.1 years old, the course of disease 6 months -62
Individual month, average 22.5 ± 2.6 months, state of an illness moderate 68, slight 82；
Matched group 150, male 71, female 79, -68 years old 20 years old age, average 45.8 ± 3.6 years old, the course of disease 5 months -61
Individual month, average 21.0 ± 3.0 months, state of an illness moderate 59, slight 91.
Two groups of patient ages, the course of disease, state of an illness comparing differences are not statistically significant (P ＞ 0.05), and two groups have comparability.
3rd, Therapeutic Method
Treatment group：Using the Chinese medicinal herbs decoction of the present invention.
Matched group：Salazosulfamide 1g, dioctahedral smectite 3g are given, 100ml normal saline, retention enema is dissolved in.
Two groups of daily retention enemas 2 times, the upper and lower noon is each 1 time, and two groups equal 10 days is 1 course for the treatment of.
4th, the criterion of curative effect
Cure：Clinical primary symptom disappears, and secondary disease disappears or basic disappearance, and pathological changes recovery is normal or ulcer focus has formed scar
Trace, stool routine examination are continuous 3 subnormal.
It is effective：Clinical primary symptom disappears substantially, and secondary disease improves degree up to more than 1 grade (the slight dull pain of abdominal part, lower abdomen pendant alleviation of pain
Gently, borborygmus are slight, and abdominal distention mitigates), intestinal mucosa pathological changes are recovered up to more than 1 grade (mild hyperaemia edema, without ulcer), stool routine examination
Red, 3/HP of leukocyte ＜.
Take a turn for the better：Clinical primary symptom improves up to more than 1 grade (3 times/day of ＜ of diarrhoea, a small amount of bloody purulent stool, stomachache are slight), intestinal mucosa disease
Become recovery extent up to more than 2 grades (intestinal mucosa gently, intermediate edema, be dispersed in ulcer ＜ 3), stool routine examination is red, leukocyte 5/
HP or so.
It is invalid：Above standard is not reached.
5th, therapeutic outcome
After two groups of treatments, four courses for the treatment of, compare curative effect：
Treatment group 150, wherein, 106 (70.7%) of fully recovering, take a turn for the better 38 (25.3%), and invalid 6 (4%) always have
Efficiency 96%；
Matched group 150, wherein, 36 (24%) of fully recovering, take a turn for the better 27 (18%), invalid 87 (58%), total effective
Rate 42%.
As can be seen here, treatment group's cure rate, total effective rate are substantially better than matched group, with comparability (P ＜ 0.05).
6th, Clinic Case
Medical record 1：Patient it is ancient certain, man, 36 years old, teacher told mucopurulent bloody stool, stomachache for 2 months 2015, suffers from diarrhoea March when medical
It is remaining, ulcerative colitiss are diagnosed as through local county people's hospital's fibercolonscopy, use herbal enema of the present invention
After 3 courses for the treatment of of liquid enema treatment, mucopurulent bloody stool, stomachache disappear, and also suffer from diarrhoea, issue then 15 days doses again, go to a doctor again
When symptom disappeared.
Medical record 2：Patient Wang, female, peasant, Jing hospital diagnosis are stain ulcer colitis.Patient's emaciated physique, complexion wither
Huang, dizzy, stomachache, tastelessness.Stool checks：Pyocyte is a little, erythrocyte, mucosanguineous fecess, stool culture, fibercolonscopy,
Colon 14cm section mucosas, edema, dense blood, being dispersed in property of intestinal segment shallow stain infectionss at rectum 8-10cm, courageous and upright mucus point in enteric cavity
Secretion is more.After two courses for the treatment of of Chinese medicinal herbs decoction enema treatment of the present invention, colitis symptoms disappear, and 1 year without recurrence.
As can be seen here, clinical enema of the invention, which can be done directly on affected part, by clearing heat and expelling damp, benefiting qi and checking blood,
Promoting blood circulation to remove obstruction in the collateral, improves colon portion blood circulation, promotes inflammatory resolution, promote the reparation of colonic ulcer, suppresses colitis reaction,
With good therapeutic effect.
It should be noted that above-described embodiment the invention is not limited in any way, all employing equivalents or equivalent change
The technical scheme obtained by the mode changed, all falls within protection scope of the present invention.
Claims (5)
1. a kind of clinical enema for treating ulcerative colitiss, it is characterised in that by following raw material Jing decoctings, concentration system
Into：
Cortex syzygii cumini 20-25g, Herba Adianti Flabellulati 15-25g, Herba Pteridis multifidae 10-12g, Herba Stellariae paniculigerae 15-17g, Radix Sophorae Flavescentiss 6-8g, feathering banyan
Root 30-40g, Rhizoma Polygoni coriacei 6-12g, Rhizoma Corydalis 12-15g, Radix Paeoniae Alba 10-12g, Fructus pruni pubescentis 7-9g, Radix Glycyrrhizae 4-6g.
2. the clinical enema for treating ulcerative colitiss according to claim 1, it is characterised in that by following original
Material Jing decoctings, concentration are made：
Cortex syzygii cumini 22g, Herba Adianti Flabellulati 20g, Herba Pteridis multifidae 11g, Herba Stellariae paniculigerae 16g, Radix Sophorae Flavescentiss 7g, Radix Fici comatae 35g, Rhizoma Polygoni coriacei
8g, Rhizoma Corydalis 13g, Radix Paeoniae Alba 11g, Fructus pruni pubescentis 8g, Radix Glycyrrhizae 5g.
3. the clinical enema for treating ulcerative colitiss according to claim 1, it is characterised in that by following original
Material Jing decoctings, concentration are made：
Cortex syzygii cumini 21g, Herba Adianti Flabellulati 16g, Herba Pteridis multifidae 11g, Herba Stellariae paniculigerae 16g, Radix Sophorae Flavescentiss 6g, Radix Fici comatae 32g, Rhizoma Polygoni coriacei
7g, Rhizoma Corydalis 12g, Radix Paeoniae Alba 10g, Fructus pruni pubescentis 7g, Radix Glycyrrhizae 6g.
4. the clinical enema for treating ulcerative colitiss according to claim 1, it is characterised in that by following original
Material Jing decoctings, concentration are made：
Cortex syzygii cumini 22g, Herba Adianti Flabellulati 17g, Herba Pteridis multifidae 10g, Herba Stellariae paniculigerae 17g, Radix Sophorae Flavescentiss 8g, Radix Fici comatae 37g, Rhizoma Polygoni coriacei
10g, Rhizoma Corydalis 14g, Radix Paeoniae Alba 12g, Fructus pruni pubescentis 8g, Radix Glycyrrhizae 4g.
5. the clinical enema for treating ulcerative colitiss according to claim 1, it is characterised in that by following original
Material Jing decoctings, concentration are made：
Cortex syzygii cumini 23g, Herba Adianti Flabellulati 24g, Herba Pteridis multifidae 11g, Herba Stellariae paniculigerae 15g, Radix Sophorae Flavescentiss 7g, Radix Fici comatae 36g, Rhizoma Polygoni coriacei
9g, Rhizoma Corydalis 13g, Radix Paeoniae Alba 11g, Fructus pruni pubescentis 9g, Radix Glycyrrhizae 5g.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611064474.8A CN106619885A (en) | 2016-11-28 | 2016-11-28 | Clinic enema for treating ulcerative colitis |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102988559A (en) * | 2012-12-04 | 2013-03-27 | 娄长丽 | Chinese medicinal enema for treating ulcerative colitis |
| CN103656090A (en) * | 2013-12-12 | 2014-03-26 | 青岛市市立医院 | Enema for treating ulcerative colitis and application thereof |
| CN103751298A (en) * | 2014-02-08 | 2014-04-30 | 曹营卿 | Traditional Chinese medicine enema for treating chronic non-specific ulcerative colitis |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102988559A (en) * | 2012-12-04 | 2013-03-27 | 娄长丽 | Chinese medicinal enema for treating ulcerative colitis |
| CN103656090A (en) * | 2013-12-12 | 2014-03-26 | 青岛市市立医院 | Enema for treating ulcerative colitis and application thereof |
| CN103751298A (en) * | 2014-02-08 | 2014-04-30 | 曹营卿 | Traditional Chinese medicine enema for treating chronic non-specific ulcerative colitis |
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