CN106605918A - Chewable tablets containing gamma-aminobutyric acid (GABA) and preparation method of chewable tablets - Google Patents

Chewable tablets containing gamma-aminobutyric acid (GABA) and preparation method of chewable tablets Download PDF

Info

Publication number
CN106605918A
CN106605918A CN201510684509.7A CN201510684509A CN106605918A CN 106605918 A CN106605918 A CN 106605918A CN 201510684509 A CN201510684509 A CN 201510684509A CN 106605918 A CN106605918 A CN 106605918A
Authority
CN
China
Prior art keywords
parts
powder
lubricant
formula
gained
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510684509.7A
Other languages
Chinese (zh)
Inventor
王永群
李成
张晓凤
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shijiazhuang Yiling Pharmaceutical Co Ltd
Original Assignee
Shijiazhuang Yiling Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shijiazhuang Yiling Pharmaceutical Co Ltd filed Critical Shijiazhuang Yiling Pharmaceutical Co Ltd
Priority to CN201510684509.7A priority Critical patent/CN106605918A/en
Publication of CN106605918A publication Critical patent/CN106605918A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The invention provides chewable tablets containing gamma-aminobutyric acid (GABA). The chewable tablets are tabletting sweets made by using gamma-aminobutyric acid, dietary fiber powder, galactooligosaccharide, mango powder, apple powder, xylooligosaccharide and the like as raw materials, have the functions of resisting anxiety, regulating emotion, improving brain vitality, and reducing blood pressure, and are convenient to take and worth of popularization and application.

Description

A kind of chewable tablet containing γ-aminobutyric acid and preparation method thereof
Technical field
The present invention relates to a kind of chewable tablet containing γ-aminobutyric acid and preparation method thereof, belongs to field of health care food.
Background technology
γ-aminobutyric acid is the natural material extracted from the Testa oryzae rich in glutamic acid, is needed by human body nutritional labeling, is deposited It is that in human body, long-term taking also will not product harmful effect.γ-aminobutyric acid(GABA)It is a kind of naturally occurring non-protein Matter aminoacid, GABA is the important inhibitory neurotransmitter in central nervous system, with important physiological function, has been ground The physiologically active for studying carefully report reduces blood pressure, promote ataraxy, promote brain blood flow, promote brain vigor, trophic nerve cell, Increase growth hormone secretion, strong liver profit kidney, improve climacteric syndrome, senile dementia etc..
Food fibre powder adopts imported raw material --- and water soluble dietary fiber, the product, with native starch as raw material, is current Unique a kind of water soluble dietary fiber used as raw-food material in the world, its fiber content is up to 85%-95%.The product is Obtain U.S. FDA " popular safety and Health food(GRAS)" certification, and obtain Japanese " specific health food " certification.Meals are fine Dimension belongs to low molecule water soluble dietary fiber, and dietary fiber is referred to as " the 7th nutrient " by nutrition educational circles, the appropriate meals of supplement Fiber can effectively pre- preventing obesity, diabetes, coronary heart disease, rectal cancer, colon cancer etc., dietary fiber is by absorbing the water of stomach enteral Point, rapid expansion makes human body produce satiety, and reduces intestinal absorption saccharide, lipid material, lubricates intestinal, promotes defecation, Suppress fat.Dietary fiber can promote intestinal peristalsis promoting, soften stool, Constipation, colon cancer and rectal cancer;In reducing blood Cholesterol, triglyceride, beneficial to obesity control;Remove the skin problems such as vivotoxin, prevention mottle formation, comedo;Reduce Absorption of the saccharide in intestinal, reduces post-prandial glycemia;Promote intestinal beneficial bacterium propagation, improve absorption of human body ability.
Oligomeric galactose is described as third generation functional factor, is one of internationally recognized prebioticses, is confirmed as by U.S. FDA GRAS materials, by Japanese legislative orientation health food.Oligomeric galactose can be utilized by the selective zymolysis of bacillus bifiduss, and with The probioticss such as the bacillus bifiduss in 40 times of incremental speed propagation human body intestinal canals, suppress the generation of harmful bacteria, the micro- life of regulating intestinal canal State is balanced, and generation is conducive to the health-care effect of host.Synthesis vitamin B group can be promoted, the absorption rate of protein is improved, promoted Enter mineral absorption;Strengthen the colonization resistance and immunity of human body intestinal canal;Human body intestinal canal is promoted to wriggle.
The selected high-quality Fructus Mangifera Indicae generated under the nonpollution environment of Hainan, Jing special process processed was both remained The local flavor fragrance of Fructus Mangifera Indicae itself, also saves the abundant nutritional labeling of Fructus Mangifera Indicae itself.Mango Fruit nutritive value is high, vitamin A contents are up to 3.8%, and containing sugared 11-19%, protein 0.65-1.31%, crude fibre 14-24.8%, Fructus Mangifera Indicae contains abundant Hu Luo Bu Su 22.81-63.04ug/g, and trace element needed by human(Selenium, calcium, phosphorus, potassium)Content is also very high.Fructus Mangifera Indicae can reduce gallbladder Sterin, triglyceride, are conducive to placing cardiovascular disease.The carotene carotene content of Fructus Mangifera Indicae is especially high, is beneficial to vision, can moisten Skin, is the good fruit of beauty of Ms.Contain chimonin in Fructus Mangifera Indicae, there is the work of obvious anti peroxidation of lipid and protection brain neuron With energy delaying cell aging, raising brain function.It can significantly improve erythrocyte catalase vigor and reduce erythrocyte blood Lactoferrin.
Fructus Mali pumilae, is not only the topmost fruit of China, is also to plant the most most fruit of wide, yield in the world.Its taste Sour and sweet palatability, it is nutritious.According to surveying and determination, per 6.5-11.2 containing Fructose gram of hectogram Fructus Mali pumilae, 2.5-3.5 gram of glucose, sucrose 1.0- 5.2 gram;Spread a kind of saying in the U.S.:" regular meal eats a Fructus Mali pumilae, just without asking doctor ".Although this talks about some exaggerations, Herba Marsileae Quadrifoliae Thus the nutrition of fruit and medical value can know something about.Again because the nutrition contained by Fructus Mali pumilae was not only comprehensive but also easily digested, So, it is especially suitable for infant, old man and patients.
The fragrance of Fructus Mali pumilae is depressed and sense of depression the good medicine for the treatment of.Brainstrust finds through test of many times, in many abnormal smells from the patients In, the fragrance of Fructus Mali pumilae is maximum to the psychological impact of people, and it has the effect for significantly eliminating psychological sense of depression.Clinical practice is demonstrate,proved It is bright, allow depression patient to smell after Fructus Mali pumilae fragrance, mental state takes a favorable turn, spiritual relaxation and happiness, and sense of depression disappears.Experiment is also demonstrate,proved Bright, insomniac smells apple aroma before sleep, can make one very fast quiet sleep.The element such as the phosphorus contained in Fructus Mali pumilae and ferrum, easily Absorbed by intestinal wall, there is supplementing the brain blood-nourishing, tranquilizing effect.Contain more potassium in Fructus Mali pumilae, sodium salt that can be superfluous with human body is combined, It is allowed to excrete.When human body intake sodium salt is excessive, a little Fructus Mali pumilaes are eaten, be conducive to balancing cylinder electrolyte.Cleaned with Fructus Mali pumilae and squeezed Juice, each serving 100 milliliters, 3 times a day, continuously takes, and is within 15 days a course for the treatment of, and Fructus Mali pumilae has the effect for reducing cholesterol level; Fructus Mali pumilae also has the double effects of relieving constipation and antidiarrheal and effect.
The oligomeric xylose that this product is obtained using corn cob enzyme process, oligomeric xylose is referred to as xylooligosaccharide, also known as " superpower bifid The factor ", " oligomeric xylose " product is recommended as nutrient health and advocates product by national Public nutrition and centre of development, with usual people Soybean oligo saccharide, oligofructose, oligomeric isomaltose used etc. are compared with unique advantage, and it can be selectively promoted The proliferation activity of intestinal bifidobacteria.Its bifidobacterium factor functional is 10-20 times of other polymerization saccharides.Oligomeric xylose has suppression Oral Pathogens and diarrhoea, the effects such as prevent constipation, the liver protecting function, reduce serum cholesterol, enhancing human body immunity power also Body can be promoted to generate various nutrient substance, including vitamin B1, B2, B6, B12, nicotinic acid and Folic Acid.
Erythritol heat is extremely low, is diabeticss and the preferable low-calorie diet of high blood glucose person.This product is selected " 0 card " sugar alcohol --- erythritol, is achieved the low heat value of product, meets the demand of more consumer groups.Erythritol exists It is distributed in nature very extensively, not only has presence on a small quantity in tissue and body fluid, in being also present in some biologies, such as:Lichens Class biology, bast-fibre biological, mushroom class biology etc., while in some fermented foods such as rice wine, medicated beer, bean milk, cheese, soy sauce all There is the presence of erythritol.Erythritol adopts fermentative Production, and closer to natural conversion and extraction, erythritol is natural The sweeting agent of zero calory, and impact of the erythritol to blood glucose is little, carbohydrate metabolism and change of blood sugar is not involved in, also with certain Antioxidant activity.Erythritol is the hot highest of solution absorption, so its refrigerant sense is highest in sugar alcohol, is had after eating Silk silk refrigerant sense.
A report of mechanism Datamonitor according to the study claims, and increasing consumer is look for the leisure of health Food succedaneum.In the whole world, the consumer that there are about 42% starts to select healthy snack food.Meanwhile, survey data is displayed that, people Sense of guilt is had when leisure food is eaten, therefore, low sugar, less salt, low fat, fibre rich, the healthy snack food of naturalization To be praised highly by market.
The content of the invention
The present invention provides a kind of containing γ-aminobutyric acid chewable tablet and preparation method thereof, fine with γ-aminobutyric acid, meals Dimension powder, oligomeric galactose, mango powder, apple powder, oligomeric xylose etc. are pressed candy made by raw material, with anxiety, are adjusted Emotion;Improve brain vigor;The function of reducing blood pressure.Simultaneously chewable tablet tablet surface area increase Jing after chewing, can promote nutrition into Divide dissolving in vivo and absorption.Taking convenience, can swallow, chew to contain and suck or take after water-dispersible.It is especially suitable old man, little Child, paralytic, the patient for swallowing difficulty and gastrointestinal function difference.
What the present invention was provided is made up containing γ-aminobutyric acid formula of chewable tablets of the raw material of following percentage of weight parts:Red moss Sugar alcohol 40-60 parts, apple powder 2-8 parts, mango powder 2-10 parts, oligomeric galactose 5-15 parts, water soluble dietary fiber 20-40 parts, Oligomeric xylose 1-6 parts, essence 0.1-0.5 parts, γ-aminobutyric acid 0.01-0.1 part, vitamin C 0.1-0.5 parts, lubricant 0.5-1 parts.
The raw material containing γ-aminobutyric acid formula of chewable tablets percentage of weight part that the present invention is provided is preferably:Erythritol 40 parts, 8 parts of apple powder, 2 parts of mango powder, 15 parts of oligomeric galactose, 20 parts of water soluble dietary fiber, 6 parts of oligomeric xylose, essence 0.1 part, 0.1 part of γ-aminobutyric acid, 0.1 part of vitamin C, 1 part of lubricant.
The raw material containing γ-aminobutyric acid formula of chewable tablets percentage of weight part that the present invention is provided is also preferably:Erythrose 60 parts of alcohol, 2 parts of apple powder, 10 parts of mango powder, 5 parts of oligomeric galactose, 40 parts of water soluble dietary fiber, 1 part of oligomeric xylose, essence 0.5 part, 0.01 part of γ-aminobutyric acid, 0.5 part of vitamin C, 0.5 part of lubricant.
The raw material containing γ-aminobutyric acid formula of chewable tablets percentage of weight part that the present invention is provided is also preferably:Erythrose 48 parts of alcohol, 4 parts of apple powder, 6 parts of mango powder, 10 parts of oligomeric galactose, 28 parts of water soluble dietary fiber, 3 parts of oligomeric xylose, essence 0.25 part, 0.05 part of γ-aminobutyric acid, 0.3 part of vitamin C, 0.8 part of lubricant.
Essence of the present invention is preferably solid essence.
Solid essence of the present invention is preferably apple banana and/or Fructus Mangifera Indicae essence.
Lubricant of the present invention is preferably the conventional lubrication of the tablets such as magnesium stearate, micropowder silica gel, polyethylene glycol 6000 Agent.
Preparation method containing γ-aminobutyric acid chewable tablet of the present invention, comprises the following steps:
(1)Crush, weigh:Vitamin C is crushed, formula material sieves respectively, weighed respectively according to formula ratio, must be weighed Powder, it is standby;
(2)Mixing:By step(1)Weighing powder of the gained in addition to lubricant is mixed, and obtains total mixed powder;
(3)Granulation:By step(2)The total mixed powder of gained, granulation is dried, and granulate obtains dry particl;
(4)Tabletting:By step(3)Gained dry particl, adds formula ratio lubricant, mixing, tabletting.
Preparation method containing γ-aminobutyric acid chewable tablet of the present invention, preferably:
(1)Crush, weigh:Vitamin C is crushed, by formula material, 50-80 mesh sieves is crossed respectively, weighed respectively according to formula ratio, Powder must be weighed, it is standby;
(2)Mixing:By step(1)Weighing powder of the gained in addition to lubricant is mixed, in putting mixer, 20-60 point of mixing Clock, obtains total mixed powder;
(3)Granulation:By step(2)The total mixed powder of gained adopts wet granulation, crosses 16 mesh sieves, and 40-70 DEG C of drying, granulate obtains dry Granule, it is standby;
(4)Tabletting:In step(3)The lubricant of formula ratio is added in gained dry particl, mixing 10-30 minutes in mixer are put, Hybrid particles, tabletting are obtained, tablet format is 0.5-1g/ pieces.
Preparation method containing γ-aminobutyric acid chewable tablet of the present invention, also preferably:
(1)Crush, weigh:Vitamin C is crushed, formula material, 60 mesh sieves are crossed respectively, weighed respectively according to formula ratio, must be claimed Amount powder, it is standby;
(2)Mixing:By step(1)Weighing powder of the gained in addition to lubricant is mixed, and in putting mixer, is mixed 30 minutes, Obtain total mixed powder;
(3)Granulation:By step(2)The total mixed powder of gained adopts wet granulation, crosses 16 mesh sieves, 50 DEG C of dryings, granulate, must do Grain, it is standby;
(4)Tabletting:In step(3)The lubricant of formula ratio is added in gained dry particl, is put in mixer and is mixed 20 minutes, obtain mixed Granule, tabletting are closed, piece weight-normality lattice are 0.7g/ pieces.
It is embodied as
Embodiment 1
Formula:
Erythritol 48g, apple powder 4g, mango powder 6g, oligomeric galactose 10g, water soluble dietary fiber 28g, oligomeric xylose 3g, Apple essence 0.15g, Fructus Mangifera Indicae essence 0.1g, γ-aminobutyric acid 0.05g, vitamin C 0.3g, magnesium stearate 0.8g
Preparation method:
((1)Crush, weigh:Vitamin C is crushed, formula material, 60 mesh sieves are crossed respectively, weighed respectively according to formula ratio, must be claimed Amount powder, it is standby;
(2)Mixing:By step(1)Weighing powder of the gained in addition to magnesium stearate is mixed, and in putting mixer, mixes 30 points Clock, obtains total mixed powder;
(3)Granulation:By step(2)The total mixed powder of gained adopts wet granulation, crosses 16 mesh sieves, 50 DEG C of dryings, granulate, must do Grain, it is standby;
(4)Tabletting:In step(3)The magnesium stearate of formula ratio is added in gained dry particl, is put in mixer and is mixed 20 minutes, obtained Hybrid particles, tabletting, piece weight-normality lattice are 0.7g/ pieces.
Embodiment 2
Formula:
Erythritol 40g, apple powder 8g, mango powder 2g, oligomeric galactose 15g, water soluble dietary fiber 20g, oligomeric xylose 6g, Apple essence 0.1g, γ-aminobutyric acid 0.1g, vitamin C 0.1g, magnesium stearate 1g.
Preparation method:
(1)Crush, weigh:Vitamin C is crushed, by formula material, 40 mesh sieves is crossed respectively, weighed respectively according to formula ratio, obtained Powder is weighed, it is standby;
(2)Mixing:By step(1)Weighing powder of the gained in addition to profit magnesium stearate is mixed, and in putting mixer, mixes 60 points Clock, obtains total mixed powder;
(3)Granulation:By step(2)The total mixed powder of gained adopts wet granulation, crosses 16 mesh sieves, 70 DEG C of dryings, granulate, must do Grain, it is standby;
(4)Tabletting:In step(3)The magnesium stearate of formula ratio is added in gained dry particl, is put in mixer and is mixed 30 minutes, obtained Hybrid particles, tabletting, piece weight-normality lattice are 0.5g/ pieces.
Embodiment 3
Formula:
Erythritol 60g, apple powder 2g, mango powder 10g, oligomeric galactose 5g, water soluble dietary fiber 40g, oligomeric xylose 1g, Fructus Mangifera Indicae essence 0.5g, γ-aminobutyric acid 0.01g, vitamin C 0.5g, magnesium stearate 0.5g.
Preparation method:
(1)Crush, weigh:Vitamin C is crushed, by formula material, 50 mesh sieves is crossed respectively, weighed respectively according to formula ratio, obtained Powder is weighed, it is standby;
(2)Mixing:By step(1)Weighing powder of the gained in addition to magnesium stearate is mixed, and in putting mixer, mixes 20 points Clock, obtains total mixed powder;
(3)Granulation:By step(2)The total mixed powder of gained adopts wet granulation, crosses 16 mesh sieves, 40 DEG C of dryings, granulate, must do Grain, it is standby;
(4)Tabletting:In step(3)The magnesium stearate of formula ratio is added in gained dry particl, is put in mixer and is mixed 10 minutes, obtained Hybrid particles, tabletting, piece weight-normality lattice are 1g/ pieces.
Embodiment 4
Formula:
Erythritol 55g, apple powder 3g, mango powder 7g, oligomeric galactose 8g, water soluble dietary fiber 22g, oligomeric xylose 5g, Fructus Mangifera Indicae essence 0.15g, γ-aminobutyric acid 0.08g, vitamin C 0.4g, micropowder silica gel 0.7g.
Preparation method:
(1)Crush, weigh:Vitamin C is crushed, by formula material, 80 mesh sieves is crossed respectively, weighed respectively according to formula ratio, obtained Powder is weighed, it is standby;
(2)Mixing:By step(1)Weighing powder of the gained in addition to micropowder silica gel is mixed, and in putting mixer, mixes 20 points Clock, obtains total mixed powder;
(3)Granulation:By step(2)The total mixed powder of gained adopts wet granulation, crosses 16 mesh sieves, 50 DEG C of dryings, granulate, must do Grain, it is standby;
(4)Tabletting:In step(3)The micropowder silica gel of formula ratio is added in gained dry particl, is put in mixer and is mixed 30 minutes, obtained Hybrid particles, tabletting, piece weight-normality lattice are 0.8g/ pieces.
Embodiment 5
Formula:
Erythritol 53g, apple powder 3g, mango powder 3g, oligomeric galactose 12g, water soluble dietary fiber 33g, oligomeric xylose 2g, Fructus Mangifera Indicae essence 0.2g, γ-aminobutyric acid 0.03g, vitamin C 0.2g, micropowder silica gel 0.6g.
Preparation method:
(1)Crush, weigh:Vitamin C is crushed, by formula material, 20 mesh sieves is crossed respectively, weighed respectively according to formula ratio, obtained Powder is weighed, it is standby;
(2)Mixing:By step(1)Weighing powder of the gained in addition to micropowder silica gel is mixed, and in putting mixer, mixes 60 points Clock, obtains total mixed powder;
(3)Granulation:By step(2)The total mixed powder of gained adopts wet granulation, crosses 16 mesh sieves, 70 DEG C of dryings, granulate, must do Grain, it is standby;
(4)Tabletting:In step(3)The micropowder silica gel of formula ratio is added in gained dry particl, is put in mixer and is mixed 10 minutes, obtained Hybrid particles, tabletting, piece weight-normality lattice are 0.6g/ pieces.
Embodiment 6
Formula:
Erythritol 46g, apple powder 7g, mango powder 3g, oligomeric galactose 6g, water soluble dietary fiber 34g, oligomeric xylose 5g, Apple essence 0.4g, γ-aminobutyric acid 0.03g, vitamin C 0.4g, polyethylene glycol 6000 0.7g.
Preparation method:
(1)Crush, weigh:Vitamin C is crushed, by formula material, 80 mesh sieves is crossed respectively, weighed respectively according to formula ratio, obtained Powder is weighed, it is standby;
(2)Mixing:By step(1)Weighing powder of the gained in addition to polyethylene glycol 6000 is mixed, in putting mixer, mixing 40 Minute, obtain total mixed powder;
(3)Granulation:By step(2)The total mixed powder of gained adopts wet granulation, crosses 16 mesh sieves, 60 DEG C of dryings, granulate, must do Grain, it is standby;
(4)Tabletting:In step(3)The polyethylene glycol 6000 of formula ratio is added in gained dry particl, is put and mix in mixer 10 points Clock, obtains hybrid particles, tabletting, and piece weight-normality lattice are 0.9g/ pieces.
Test example:In order to identify the performance of chewable tablet, the evaluation group of 15 people is constituted by professional, with the hard of chewable tablet Degree, outward appearance, mouthfeel are index, and the chewable tablet of above example is scored respectively, and 10 points is full marks, illustrates the property of chewable tablet Can preferably, test concrete outcome is as follows:
Outward appearance Mouthfeel Hardness(kg/cm2 Scoring
Embodiment 1 Surface is complete, bright and clean Tasty and refreshing, fine and smooth, sweet and sour taste, free from extraneous odour 4.8 9.0
Embodiment 2 Surface is complete, bright and clean Tasty and refreshing, fine and smooth, sweet and sour taste, free from extraneous odour 5.3 9.5
Embodiment 3 Surface is complete, bright and clean Tasty and refreshing, fine and smooth, sweet and sour taste, free from extraneous odour 5.1 9.1
Embodiment 4 Surface is complete, bright and clean Tasty and refreshing, fine and smooth, sweet and sour taste, free from extraneous odour 5.2 9.3
Embodiment 5 Surface is complete, bright and clean Tasty and refreshing, fine and smooth, sweet and sour taste, free from extraneous odour 5.5 8.7
Embodiment 6 Surface is complete, bright and clean Tasty and refreshing, fine and smooth, sweet and sour taste, free from extraneous odour 5.2 9.1
From above result of the test, the chewable tablet prepared using the formula and preparation method thereof of embodiment 1-6, the complete light in surface Sliding, mouthfeel is tasty and refreshing, fine and smooth, sweet and sour taste, and free from extraneous odour, hardness is suitable, and expert analysis mode is illustrated using we more than 8.5 points Chewable tablet better performances prepared by face method, are suitable for industrialized great production.

Claims (10)

1. a kind of chewable tablet containing γ-aminobutyric acid, it is characterised in that the formula of chewable tablets is by following percentage of weight parts Raw material is made:Erythritol 40-60 parts, apple powder 2-8 parts, mango powder 2-10 parts, oligomeric galactose 5-15 parts, aqueous soluble dietary Fiber 20-40 parts, oligomeric xylose 1-6 parts, essence 0.1-0.5 parts, γ-aminobutyric acid 0.01-0.1 part, vitamin C 0.1-0.5 Part, lubricant 0.5-1 parts.
2. chewable tablet according to claim 1, it is characterised in that the formula of chewable tablets by following percentage of weight parts original Material is made:It is 40 parts of erythritol, 8 parts of apple powder, 2 parts of mango powder, 15 parts of oligomeric galactose, 20 parts of water soluble dietary fiber, low 6 parts of xylan, 0.1 part of essence, 0.1 part of γ-aminobutyric acid, 0.1 part of vitamin C, 1 part of lubricant.
3. chewable tablet according to claim 1, it is characterised in that the formula of chewable tablets by following percentage of weight parts original Material is made:It is 60 parts of erythritol, 2 parts of apple powder, 10 parts of mango powder, 5 parts of oligomeric galactose, 40 parts of water soluble dietary fiber, low 1 part of xylan, 0.5 part of essence, 0.01 part of γ-aminobutyric acid, 0.5 part of vitamin C, 0.5 part of lubricant.
4. chewable tablet according to claim 1, it is characterised in that formula of chewable tablets by following percentage of weight parts raw material system Into:48 parts of erythritol, 4 parts of apple powder, 6 parts of mango powder, 10 parts of oligomeric galactose, 28 parts of water soluble dietary fiber, oligomeric wood 3 parts of sugar, 0.25 part of essence, 0.05 part of γ-aminobutyric acid, 0.3 part of vitamin C, 0.8 part of lubricant.
5. the chewable tablet according to any one of claim 1-4, it is characterised in that the essence is solid essence.
6. chewable tablet according to claim 5, it is characterised in that the solid essence is that apple essence and/or Fructus Mangifera Indicae are fragrant Essence.
7. the chewable tablet according to any one of claim 1-4, it is characterised in that the lubricant is magnesium stearate.
8. the preparation method of the chewable tablet according to any one of claim 1-4, it is characterised in that comprise the following steps:
(1)Crush, weigh:Vitamin C is crushed, formula material sieves respectively, weighed respectively according to formula ratio, must be weighed Powder, it is standby;
(2)Mixing:By step(1)Weighing powder of the gained in addition to lubricant is mixed, and obtains total mixed powder;
(3)Granulation:By step(2)The total mixed powder of gained, granulation is dried, and granulate obtains dry particl;
(4)Tabletting:By step(3)Gained dry particl, adds formula ratio lubricant, mixing, tabletting.
9. the preparation method of chewable tablet according to claim 8, it is characterised in that comprise the following steps:
(1)Crush, weigh:Vitamin C is crushed, by formula material, 20-80 mesh sieves is crossed respectively, weighed respectively according to formula ratio, Powder must be weighed, it is standby;
(2)Mixing:By step(1)Weighing powder of the gained in addition to lubricant is mixed, in putting mixer, 20-60 point of mixing Clock, obtains total mixed powder;
(3)Granulation:By step(2)The total mixed powder of gained adopts wet granulation, crosses 16 mesh sieves, and 40-70 DEG C of drying, granulate obtains dry Granule, it is standby;
(4)Tabletting:In step(3)The lubricant of formula ratio is added in gained dry particl, mixing 10-30 minutes in mixer are put, Hybrid particles, tabletting are obtained, tablet format is 0.5-1g/ pieces.
10. the preparation method of chewable tablet according to claim 9, it is characterised in that comprise the following steps:
(1)Crush, weigh:Vitamin C is crushed, formula material, 60 mesh sieves are crossed respectively, weighed respectively according to formula ratio, must be claimed Amount powder, it is standby;
(2)Mixing:By step(1)Weighing powder of the gained in addition to lubricant is mixed, and in putting mixer, is mixed 30 minutes, Obtain total mixed powder;
(3)Granulation:By step(2)The total mixed powder of gained adopts wet granulation, crosses 16 mesh sieves, 50 DEG C of dryings, granulate, must do Grain, it is standby;
(4)Tabletting:In step(3)The lubricant of formula ratio is added in gained dry particl, is put in mixer and is mixed 20 minutes, obtain mixed Granule, tabletting are closed, piece weight-normality lattice are 0.7g/ pieces.
CN201510684509.7A 2015-10-22 2015-10-22 Chewable tablets containing gamma-aminobutyric acid (GABA) and preparation method of chewable tablets Pending CN106605918A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510684509.7A CN106605918A (en) 2015-10-22 2015-10-22 Chewable tablets containing gamma-aminobutyric acid (GABA) and preparation method of chewable tablets

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510684509.7A CN106605918A (en) 2015-10-22 2015-10-22 Chewable tablets containing gamma-aminobutyric acid (GABA) and preparation method of chewable tablets

Publications (1)

Publication Number Publication Date
CN106605918A true CN106605918A (en) 2017-05-03

Family

ID=58610325

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510684509.7A Pending CN106605918A (en) 2015-10-22 2015-10-22 Chewable tablets containing gamma-aminobutyric acid (GABA) and preparation method of chewable tablets

Country Status (1)

Country Link
CN (1) CN106605918A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107156411A (en) * 2017-05-10 2017-09-15 苏州工业园区尚融科技有限公司 It is a kind of to improve the tasty and refreshing sugar of sugar-free of immune function of human body

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103385471A (en) * 2013-07-10 2013-11-13 山东禹城禹王生态食业有限公司 Nutrition and healthcare double-protein chewing tablet and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103385471A (en) * 2013-07-10 2013-11-13 山东禹城禹王生态食业有限公司 Nutrition and healthcare double-protein chewing tablet and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107156411A (en) * 2017-05-10 2017-09-15 苏州工业园区尚融科技有限公司 It is a kind of to improve the tasty and refreshing sugar of sugar-free of immune function of human body

Similar Documents

Publication Publication Date Title
CN104643250B (en) It is a kind of can bidirectional modulation body weight improve inferior health solid beverage
CN102224891B (en) Sugar alcohol honey apple jam and preparation method thereof
CN106509856A (en) Chewing tablet containing collagen and preparation method thereof
CN106605904A (en) Chewable tablets containing acerola cherry powder and preparation method of chewable tablets
CN102511861A (en) Thickened red jujube pulp added with oligosaccharide
CN104664370A (en) Chewable flax tablet
CN105379927A (en) Low-calorie sugar-free hard candy containing meso-erythritol and preparation method thereof
CN102511864B (en) Jujube high-consistency stock
CN107455625A (en) A kind of nutrient for plants beverage and its preparation technology with antifatigue weight losing function
CN103371318B (en) Dietary nutrition replenishing food
CN102090563B (en) Relaxing and sleeping health-care food and preparation method thereof
CN102919648B (en) Nutrient and health-care highland barley jelly and preparation method thereof
CN106387900A (en) Composition for regulating blood lipid, blood pressure and blood sugar, as well as application thereof
CN105341300A (en) Health-care candies suitable for children to eat
CN107410631A (en) A kind of multi-functional glycoconjugate and preparation method and application
CN106605918A (en) Chewable tablets containing gamma-aminobutyric acid (GABA) and preparation method of chewable tablets
CN102048134A (en) Five-material vegetable nutraceutical and preparation method thereof
CN106509589A (en) Chewing tablet containing xanthophyll and preparation method thereof
CN108634177A (en) A kind of health type high protein rice flour
CN107439866A (en) Matrimony vine chickpea plant nutrients beverage and its preparation technology
CN105087284B (en) A kind of compound raspberry health preserving wine and preparation method thereof
CN102511870A (en) Thickened red jujube pulp beneficial to losing weight
CN102511860B (en) Thickened red jujube pulp added with phytosterin and being suitable for being taken by pregnant women
CN106262882A (en) Tremella sweet potato flour instant food and preparation method thereof
CN102885364A (en) Corn beverage and its preparation method

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20170503